Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	TRC complex	SGTB SGTA	2.42e-06	2	33	2	GO:0072380
GeneOntologyCellularComponent	ER membrane insertion complex	SGTB SGTA	2.17e-04	14	33	2	GO:0072379
GeneOntologyCellularComponent	node of Ranvier	NFASC NRCAM	4.51e-04	20	33	2	GO:0033268
GeneOntologyCellularComponent	axon initial segment	NFASC NRCAM	9.55e-04	29	33	2	GO:0043194
HumanPheno	Decreased circulating level of specific antibody	CD19 FASLG ALG12	4.81e-05	50	8	3	HP:0012475
HumanPheno	Impaired antigen-specific response	CD19 FASLG ALG12	7.15e-05	57	8	3	HP:0031404
Domain	Neurofascin/L1/NrCAM_C	CHL1 NFASC NRCAM	2.01e-08	4	33	3	IPR026966
Domain	Bravo_FIGEY	CHL1 NFASC NRCAM	2.01e-08	4	33	3	PF13882
Domain	SGTA_dimer	SGTB SGTA	3.03e-06	2	33	2	PF16546
Domain	SGTA_dimer	SGTB SGTA	3.03e-06	2	33	2	IPR032374
Domain	Ig_I-set	CHL1 IGSF10 NFASC NRCAM CDON	1.95e-05	190	33	5	IPR013098
Domain	I-set	CHL1 IGSF10 NFASC NRCAM CDON	1.95e-05	190	33	5	PF07679
Domain	HELP	EML5 EML6	4.52e-05	6	33	2	PF03451
Domain	HELP	EML5 EML6	4.52e-05	6	33	2	IPR005108
Domain	IGc2	CHL1 IGSF10 NFASC NRCAM CDON	5.38e-05	235	33	5	SM00408
Domain	Ig_sub2	CHL1 IGSF10 NFASC NRCAM CDON	5.38e-05	235	33	5	IPR003598
Domain	EGF	ADAM23 ATRNL1 PCSK6 JAG1 TMEFF2	5.38e-05	235	33	5	SM00181
Domain	EGF-like_dom	ADAM23 ATRNL1 PCSK6 JAG1 TMEFF2	7.08e-05	249	33	5	IPR000742
Domain	IG	CHL1 IGSF10 NFASC NRCAM CD19 CDON	8.37e-05	421	33	6	SM00409
Domain	Ig_sub	CHL1 IGSF10 NFASC NRCAM CD19 CDON	8.37e-05	421	33	6	IPR003599
Domain	EGF_extracell	ADAM23 ATRNL1 JAG1	1.61e-04	60	33	3	IPR013111
Domain	EGF_2	ADAM23 ATRNL1 JAG1	1.61e-04	60	33	3	PF07974
Domain	fn3	CHL1 NFASC NRCAM CDON	1.83e-04	162	33	4	PF00041
Domain	IG_LIKE	CHL1 IGSF10 NFASC NRCAM CD19 CDON	1.94e-04	491	33	6	PS50835
Domain	TPR	TOMM70 DELE1 SGTB SGTA	1.97e-04	165	33	4	PS50005
Domain	TPR_REGION	TOMM70 DELE1 SGTB SGTA	1.97e-04	165	33	4	PS50293
Domain	Ig-like_dom	CHL1 IGSF10 NFASC NRCAM CD19 CDON	2.21e-04	503	33	6	IPR007110
Domain	FN3	CHL1 NFASC NRCAM CDON	3.05e-04	185	33	4	SM00060
Domain	ig	CHL1 NFASC NRCAM CDON	3.37e-04	190	33	4	PF00047
Domain	Immunoglobulin	CHL1 NFASC NRCAM CDON	3.37e-04	190	33	4	IPR013151
Domain	FN3	CHL1 NFASC NRCAM CDON	4.02e-04	199	33	4	PS50853
Domain	-	TOMM70 DELE1 SGTB SGTA	4.66e-04	207	33	4	1.25.40.10
Domain	FN3_dom	CHL1 NFASC NRCAM CDON	4.83e-04	209	33	4	IPR003961
Domain	VWC_out	MUC5AC JAG1	5.08e-04	19	33	2	SM00215
Domain	TPR_1	TOMM70 SGTB SGTA	5.32e-04	90	33	3	PF00515
Domain	TPR_1	TOMM70 SGTB SGTA	5.32e-04	90	33	3	IPR001440
Domain	Apc4_WD40_dom	EML5 EML6	5.64e-04	20	33	2	IPR024977
Domain	ANAPC4_WD40	EML5 EML6	5.64e-04	20	33	2	PF12894
Domain	TPR-like_helical_dom	TOMM70 DELE1 SGTB SGTA	7.27e-04	233	33	4	IPR011990
Domain	EGF_3	ADAM23 ATRNL1 JAG1 TMEFF2	7.51e-04	235	33	4	PS50026
Domain	-	CHL1 IGSF10 NFASC NRCAM CD19 CDON	9.55e-04	663	33	6	2.60.40.10
Domain	EGF_1	ADAM23 ATRNL1 JAG1 TMEFF2	1.02e-03	255	33	4	PS00022
Domain	EGF-like_CS	ADAM23 ATRNL1 JAG1 TMEFF2	1.11e-03	261	33	4	IPR013032
Domain	EGF_2	ADAM23 ATRNL1 JAG1 TMEFF2	1.17e-03	265	33	4	PS01186
Domain	Ig-like_fold	CHL1 IGSF10 NFASC NRCAM CD19 CDON	1.32e-03	706	33	6	IPR013783
Domain	TPR	TOMM70 SGTB SGTA	1.51e-03	129	33	3	SM00028
Domain	TPR_repeat	TOMM70 SGTB SGTA	1.65e-03	133	33	3	IPR019734
Domain	VWC	MUC5AC JAG1	2.05e-03	38	33	2	SM00214
Domain	TPR-contain_dom	TOMM70 SGTB SGTA	2.32e-03	150	33	3	IPR013026
Domain	VWF_dom	MUC5AC JAG1	2.49e-03	42	33	2	IPR001007
Domain	TPR_8	TOMM70 SGTA	3.94e-03	53	33	2	PF13181
Domain	Quinoprotein_ADH-like_supfam	EML5 EML6	3.94e-03	53	33	2	IPR011047
Pathway	REACTOME_NEUROFASCIN_INTERACTIONS	NFASC NRCAM	5.80e-05	7	24	2	M27380
Pubmed	Structural and functional evolution of the L1 family: are four adhesion molecules better than one?	CHL1 NFASC NRCAM	3.11e-09	4	33	3	10662501
Pubmed	EphB regulates L1 phosphorylation during retinocollicular mapping.	CHL1 NFASC NRCAM	2.72e-08	7	33	3	22579729
Pubmed	A role for Nr-CAM in the patterning of binocular visual pathways.	CHL1 NFASC NRCAM	1.70e-07	12	33	3	16701205
Pubmed	Abnormal axonal guidance and brain anatomy in mouse mutants for the cell recognition molecules close homolog of L1 and NgCAM-related cell adhesion molecule.	CHL1 NRCAM	8.73e-07	2	33	2	18588951
Pubmed	A brain-specific isoform of small glutamine-rich tetratricopeptide repeat-containing protein binds to Hsc70 and the cysteine string protein.	SGTB SGTA	8.73e-07	2	33	2	12878599
Pubmed	Neurofascin induces neurites by heterophilic interactions with axonal NrCAM while NrCAM requires F11 on the axonal surface to extend neurites.	NFASC NRCAM	8.73e-07	2	33	2	8922386
Pubmed	Intratumoral CRH modulates immuno-escape of ovarian cancer cells through FasL regulation.	FASLG CRHR1	2.62e-06	3	33	2	17667919
Pubmed	Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity.	CD19 FASLG	2.62e-06	3	33	2	17509906
Pubmed	T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.	CD19 FASLG	2.62e-06	3	33	2	15148335
Pubmed	Peptide analogs of thymopentin distinguish distinct thymopoietin receptor specificities on two human T cell lines.	SGTB SGTA	2.62e-06	3	33	2	2158125
Pubmed	Bergmann glia and the recognition molecule CHL1 organize GABAergic axons and direct innervation of Purkinje cell dendrites.	CHL1 NRCAM	2.62e-06	3	33	2	18447583
Pubmed	Prevention of autoimmunity and control of recall response to exogenous antigen by Fas death receptor ligand expression on T cells.	CD19 FASLG	2.62e-06	3	33	2	19013083
Pubmed	Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas.	CD19 FASLG	5.23e-06	4	33	2	27573825
Pubmed	Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments.	NFASC NRCAM	5.23e-06	4	33	2	11724816
Pubmed	Expression of four immunoglobulin superfamily adhesion molecules (L1, Nr-CAM/Bravo, neurofascin/ABGP, and N-CAM) in the developing mouse spinal cord.	NFASC NRCAM	5.23e-06	4	33	2	7706555
Pubmed	Proteome-wide analysis of phospho-regulated PDZ domain interactions.	FASTKD5 NET1 CRHR1	8.71e-06	42	33	3	30126976
Pubmed	A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier.	NFASC NRCAM	1.31e-05	6	33	2	20188654
Pubmed	Myocilin mediates myelination in the peripheral nervous system through ErbB2/3 signaling.	NFASC NRCAM	1.31e-05	6	33	2	23897819
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	CHL1 IGSF10 NRCAM CDON	1.67e-05	162	33	4	25826454
Pubmed	Genes for the neuronal immunoglobulin domain cell adhesion molecules neurofascin and Nr-CAM map to mouse chromosomes 1 and 12 and homologous human chromosomes.	NFASC NRCAM	1.83e-05	7	33	2	8672144
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SGTB NRCAM ADAM23 ARHGAP21 ATRNL1 SGTA PCSK6 USP33	2.07e-05	1285	33	8	35914814
Pubmed	p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts in mouse fetal liver.	CD19 JAG1	2.44e-05	8	33	2	18515089
Pubmed	Neurofascin 140 is an embryonic neuronal neurofascin isoform that promotes the assembly of the node of Ranvier.	NFASC NRCAM	3.13e-05	9	33	2	25653379
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	MUC5AC ATRNL1 RASGRP3	4.26e-05	71	33	3	33541421
Pubmed	Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study.	MUC5AC CRHR1	4.78e-05	11	33	2	24429156
Pubmed	Notch-Tnf signalling is required for development and homeostasis of arterial valves.	FASLG JAG1	4.78e-05	11	33	2	26491108
Pubmed	Neuronal Ig/Caspr recognition promotes the formation of axoaxonic synapses in mouse spinal cord.	CHL1 NRCAM	5.73e-05	12	33	2	24411736
Pubmed	Pioneering axons regulate neuronal polarization in the developing cerebral cortex.	CHL1 NRCAM	6.77e-05	13	33	2	24559674
Pubmed	Interferon-driven deletion of antiviral B cells at the onset of chronic infection.	CD19 FASLG	7.89e-05	14	33	2	27872905
Pubmed	Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development.	JAG1 CDON	1.64e-04	20	33	2	16169709
Pubmed	Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors.	MUC5AC JAG1	3.02e-04	27	33	2	32878924
Pubmed	Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.	MUC5AC JAG1	3.02e-04	27	33	2	21791528
Pubmed	Notch signaling in stomach epithelial stem cell homeostasis.	MUC5AC JAG1	3.49e-04	29	33	2	21402740
Pubmed	Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP.	FASTKD5 MYO1B	3.74e-04	30	33	2	37019383
Pubmed	EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.	SGTB SGTA USP33	3.90e-04	150	33	3	32423001
Pubmed	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	CHL1 TMEFF2	4.53e-04	33	33	2	21658281
Pubmed	Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility.	TOMM70 SGTA	4.53e-04	33	33	2	17558393
Pubmed	The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways.	MUC5AC JAG1	4.53e-04	33	33	2	23213461
Pubmed	Notch signaling in postnatal pituitary expansion: proliferation, progenitors, and cell specification.	CRHR1 JAG1	5.69e-04	37	33	2	24673559
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TOMM70 NRCAM ARHGAP21 USP33	5.78e-04	407	33	4	12693553
Pubmed	Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.	MUC5AC JAG1	7.00e-04	41	33	2	22675208
Pubmed	Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors.	CHL1 NRCAM	8.43e-04	45	33	2	22696295
Interaction	CDH15 interactions	SGTB SGTA CDON	3.81e-06	19	33	3	int:CDH15
Interaction	UPK3A interactions	SGTB SGTA	1.56e-05	4	33	2	int:UPK3A
Interaction	PRB4 interactions	SGTB SGTA	2.59e-05	5	33	2	int:PRB4
Interaction	PAGE3 interactions	SGTB SGTA	3.88e-05	6	33	2	int:PAGE3
Interaction	C1QTNF5 interactions	SGTB SGTA	3.88e-05	6	33	2	int:C1QTNF5
Interaction	ZDHHC15 interactions	MUC5AC ATRNL1 RASGRP3 TMEFF2	5.02e-05	125	33	4	int:ZDHHC15
Interaction	WFDC12 interactions	SGTB SGTA	7.24e-05	8	33	2	int:WFDC12
Interaction	KCNE5 interactions	SGTB SGTA	9.29e-05	9	33	2	int:KCNE5
Interaction	RNASE10 interactions	SGTB SGTA	1.16e-04	10	33	2	int:RNASE10
Interaction	C1QTNF6 interactions	SGTB SGTA	1.16e-04	10	33	2	int:C1QTNF6
Interaction	MAGI3 interactions	NRCAM NET1 CRHR1	1.49e-04	63	33	3	int:MAGI3
Interaction	L1CAM interactions	CHL1 NFASC NRCAM	1.56e-04	64	33	3	int:L1CAM
Interaction	ZG16 interactions	SGTB SGTA	1.70e-04	12	33	2	int:ZG16
Interaction	FGF21 interactions	SGTB SGTA	1.70e-04	12	33	2	int:FGF21
Interaction	SHISA5 interactions	SGTB SGTA	2.01e-04	13	33	2	int:SHISA5
Interaction	SOD3 interactions	SGTB SGTA	2.01e-04	13	33	2	int:SOD3
Interaction	C5orf46 interactions	SGTB SGTA	3.08e-04	16	33	2	int:C5orf46
Interaction	SERPINI2 interactions	SGTB SGTA	3.91e-04	18	33	2	int:SERPINI2
Interaction	PRAP1 interactions	SGTB SGTA	3.91e-04	18	33	2	int:PRAP1
Interaction	SRGAP1 interactions	TOMM70 FASLG ARHGAP21	4.55e-04	92	33	3	int:SRGAP1
Interaction	SRGN interactions	SGTB SGTA	4.85e-04	20	33	2	int:SRGN
Interaction	SYT4 interactions	SGTB SGTA	5.36e-04	21	33	2	int:SYT4
Cytoband	Ensembl 112 genes in cytogenetic band chr2q32	MYO1B TMEFF2	2.86e-03	110	33	2	chr2q32
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	CHL1 IGSF10 NFASC NRCAM CDON	4.38e-06	161	28	5	593
GeneFamily	Fibronectin type III domain containing	CHL1 NFASC NRCAM CDON	1.02e-04	160	28	4	555
GeneFamily	Immunoglobulin like domain containing	CHL1 NRCAM CD19 CDON	2.11e-04	193	28	4	594
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TOMM70 SGTB SGTA	7.31e-04	115	28	3	769
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	CD19 FASLG JAG1	2.25e-02	394	28	3	471
Coexpression	GSE22886_DC_VS_MONOCYTE_UP	SLC6A8 TOMM70 NET1 RASGRP3 JAG1	4.91e-06	200	33	5	M4471
Coexpression	ZHENG_GLIOBLASTOMA_PLASTICITY_UP	CHL1 MYO1B NRCAM JAG1 TMEFF2	1.42e-05	249	33	5	M1796
Coexpression	ZHENG_GLIOBLASTOMA_PLASTICITY_UP	CHL1 MYO1B NRCAM JAG1 TMEFF2	1.65e-05	257	33	5	MM1231
Coexpression	ZHONG_PFC_C4_PTGDS_POS_OPC	NFASC ADAM23 SGTA TMEFF2	3.42e-05	147	33	4	M39099
CoexpressionAtlas	Myeloid Cells, DC.4+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3	MYO1B PLA2G2D ADAM23 ATRNL1 RASGRP3 JAG1 CDON	2.24e-06	400	33	7	GSM538242_500
CoexpressionAtlas	Myeloid Cells, DC.IIhilang+103+11blo.SLN, MHCIIhi CD11c+ Langerin+ CD103+ CD11b-, Lymph Node, avg-3	EML5 NET1 ADAM23 ATRNL1 JAG1 EML6	2.81e-05	393	33	6	GSM538268_500
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b-.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-2	EML5 NET1 ADAM23 ATRNL1 RASGRP3 JAG1	3.23e-05	403	33	6	GSM605834_500
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b-.MLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-3	EML5 NET1 ADAM23 ATRNL1 RASGRP3 JAG1	3.96e-05	418	33	6	GSM605836_500
CoexpressionAtlas	lymph node	CD19 FASLG PLA2G2D GZMK EML6	5.48e-05	268	33	5	lymph node
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_1000	IGSF10 SGTB NET1 ATRNL1 TMEFF2	1.11e-04	311	33	5	gudmap_dev gonad_e11.5_M_GonMes_Sma_k3_1000
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000	IGSF10 EML5 NRCAM ADAM23 ATRNL1 RASGRP3 TMEFF2	1.12e-04	734	33	7	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	IGSF10 NET1 ATRNL1 RASGRP3 PCSK6 JAG1 TMEFF2	1.48e-04	768	33	7	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	IGSF10 ADAM23 ATRNL1 PCSK6 JAG1 TMEFF2 CDON	1.54e-04	773	33	7	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	IGSF10 SGTB ADAM23 ATRNL1 PCSK6 JAG1 TMEFF2	1.59e-04	777	33	7	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500	IGSF10 ADAM23 JAG1 TMEFF2 CDON	2.08e-04	356	33	5	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlas	Myeloid Cells, DC.103-11b+.LuLN, MHCII+ CD11c+ CD8- CD11b+ CD103-, Lymph Node, avg-3	NET1 ADAM23 ATRNL1 RASGRP3 JAG1	2.36e-04	366	33	5	GSM854255_500
CoexpressionAtlas	Myeloid Cells, DC.IIhilang+103+11blo.SLN, MHCIIhi CD11c+ Langerin+ CD103+ CD11b-, Lymph Node, avg-3	NET1 ADAM23 JAG1	2.50e-04	79	33	3	GSM538268_100
CoexpressionAtlas	dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_1000	SGTB EML5 NRCAM ADAM23	2.62e-04	202	33	4	gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k3_1000
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b-.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-2	NET1 ADAM23 JAG1	2.69e-04	81	33	3	GSM605834_100
CoexpressionAtlas	dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_1000	NFASC SGTB EML5 NRCAM ADAM23 SGTA TMEFF2	2.70e-04	847	33	7	gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_1000
CoexpressionAtlas	Myeloid Cells, DC.103+11b-.LuLN, MHCII+ CD11c+ CD8- CD11b- CD103+, Lymph Node, avg-3	NET1 ADAM23 JAG1	2.79e-04	82	33	3	GSM854243_100
CoexpressionAtlas	Myeloid Cells, DC.IIhilang-103-11blo.SLN, MHCIIhi CD11c+ Langerin- CD103- CD11b-, Lymph Node, avg-3	NET1 ADAM23 JAG1	2.79e-04	82	33	3	GSM538277_100
CoexpressionAtlas	Myeloid Cells, DC.4+.Sp, CD11b CD45 CD4 CD11c CD8a, Spleen, avg-1	MYO1B ADAM23 RASGRP3 JAG1 CDON	2.88e-04	382	33	5	GSM538248_500
CoexpressionAtlas	Myeloid Cells, DC.4+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1	MYO1B ADAM23 RASGRP3 JAG1 CDON	2.91e-04	383	33	5	GSM605826_500
CoexpressionAtlas	Myeloid Cells, DC.IIhilang-103-11blo.SLN, MHCIIhi CD11c+ Langerin- CD103- CD11b-, Lymph Node, avg-3	NET1 ADAM23 ATRNL1 RASGRP3 JAG1	3.02e-04	386	33	5	GSM538277_500
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_1000	EML5 NRCAM ADAM23 TMEFF2	3.09e-04	211	33	4	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_1000
CoexpressionAtlas	Myeloid Cells, DC.4+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-3	MYO1B ADAM23 RASGRP3 JAG1 CDON	3.20e-04	391	33	5	GSM538249_500
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b-.SLN, CD11b-FITC CD4-PE CD11c-eFluor780 CD8a-eFluor450 C, Lymph Node, avg-3	NET1 ADAM23 JAG1	3.21e-04	86	33	3	GSM854291_100
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b-.MLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-3	NET1 ADAM23 JAG1	3.32e-04	87	33	3	GSM605836_100
CoexpressionAtlas	Myeloid Cells, DC.IIhilang+103-11b+.SLN, MHCIIhi CD11c+ Langerin+ CD103- CD11b+, Lymph Node, avg-3	NET1 PLA2G2D ADAM23 ATRNL1 JAG1	4.03e-04	411	33	5	GSM538271_500
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b+.MLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-2	NET1 ADAM23 ATRNL1 RASGRP3 JAG1	4.12e-04	413	33	5	GSM538263_500
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-1	NET1 ADAM23 ATRNL1 RASGRP3 JAG1	4.16e-04	414	33	5	GSM538262_500
CoexpressionAtlas	Myeloid Cells, DC.8+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3	NET1 ADAM23 RASGRP3 JAG1 CDON	4.44e-04	420	33	5	GSM538252_500
CoexpressionAtlas	Myeloid Cells, DC.8+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3	NET1 ADAM23 RASGRP3 JAG1 CDON	4.69e-04	425	33	5	GSM538255_500
CoexpressionAtlas	dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_top-relative-expression-ranked_500	NFASC EML5 NRCAM ADAM23 TMEFF2	5.49e-04	440	33	5	gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#2	NRCAM ALG12 EML6	8.90e-04	122	33	3	Facebase_RNAseq_e8.5_Floor Plate_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#4	SGTB EML5 JAG1	9.33e-04	124	33	3	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K4
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#1_top-relative-expression-ranked_500	NET1 ATRNL1 TMEFF2	9.55e-04	125	33	3	gudmap_dev gonad_e11.5_M_GonMes_Sma_k1_500
CoexpressionAtlas	dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000	EML5 ADAM23 TMEFF2	1.09e-03	131	33	3	gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k4_1000
CoexpressionAtlas	cerebral cortex	CHL1 NFASC SGTB NRCAM ADAM23 ATRNL1 CRHR1 TMEFF2	1.25e-03	1428	33	8	cerebral cortex
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000	IGSF10 SGTB NET1 ATRNL1 PCSK6 CDON	1.28e-03	797	33	6	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	IGSF10 NET1 ATRNL1 TMEFF2	1.31e-03	310	33	4	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CHL1 NRCAM MEIOC ADAM23 USP33	1.83e-07	175	33	5	bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3\|TCGA-Lung / Sample_Type by Project: Shred V9	SLC6A8 NRCAM ADAM23 ATRNL1 JAG1	2.34e-07	184	33	5	ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 NFASC EML5 NRCAM TMEFF2	3.37e-07	198	33	5	800ade4261695f2efd869d2b1243571de963c431
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CHL1 MYO1B CD19 RASGRP3	3.24e-06	138	33	4	76be06136c83c167cedece7515228ed4d29dd1f0
ToppCell	droplet-Liver-LIVER_NPC-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CD19 FASLG GZMK	5.67e-06	159	33	4	997963d879e5819683793cddf5e1acff1b81a1b8
ToppCell	droplet-Liver-LIVER_NPC\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CD19 FASLG GZMK	5.67e-06	159	33	4	e4eaa88772835d6b78e1a18a0cec52de51e80339
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-Klrb1a/b/c(-)_NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 FASLG JAG1 GZMK	6.57e-06	165	33	4	eeb58d4db64ad37dc6b441eab22b05c24862e1a9
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CHL1 MYO1B CD19 RASGRP3	6.57e-06	165	33	4	fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCell	droplet-Lung-nan-3m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 EML5 FASLG GZMK	7.22e-06	169	33	4	9df20ce0c2661eb4b3ce4c0b857e38485fabd46d
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 EML5 FASLG GZMK	7.22e-06	169	33	4	7ec2b6b55f51edc0084db73eaf42ae319a24f77a
ToppCell	droplet-Liver-LIVER_NPC-30m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CD19 FASLG GZMK	7.39e-06	170	33	4	26178277bf9c7f2f06b5c0b03d4b69d78e9580c4
ToppCell	normal_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	DELE1 NET1 ARHGAP21 GZMK	7.74e-06	172	33	4	0657c736f3c52d25cf7f652eac005ddcde9232ef
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CHL1 MYO1B CD19 RASGRP3	7.74e-06	172	33	4	62ed3b70fa1f6c84ea80ff00f60d2562be292e9d
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CHL1 MYO1B CD19 RASGRP3	8.47e-06	176	33	4	ad05dd934f4ac2e656b3455de091f4c8772de6c8
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CD19 FASLG GZMK	8.47e-06	176	33	4	4e79c215cb6ace7d79b362a2e29a5228c54ce375
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CHL1 NFASC EML5 TMEFF2	9.06e-06	179	33	4	df6d2cdc4e204ce1a4628dc71dfbc5e6c6309b2a
ToppCell	wk_15-18-Epithelial-PNS-KCNIP4+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CHL1 NFASC EML5 TMEFF2	9.06e-06	179	33	4	e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCell	Healthy-B_memory\|Healthy / disease group, cell group and cell class	CD19 PLA2G2D RASGRP3 EML6	9.46e-06	181	33	4	7b903076efb90026b9845af0c7a840901451193a
ToppCell	wk_15-18-Epithelial-PNS-SST+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CHL1 EML5 NRCAM TMEFF2	9.67e-06	182	33	4	a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCell	droplet-Lung-nan-21m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CD19 FASLG GZMK	9.88e-06	183	33	4	d03a35fd69a1307b99928b73fd5879aed2fda2b5
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CHL1 NRCAM CD19 RASGRP3	9.88e-06	183	33	4	01664fce6b70a02c9d39d747b6a6aabc86d57bc2
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CHL1 NFASC EML5 TMEFF2	1.01e-05	184	33	4	571136c832cb8c08457744152231537aa8e8abd7
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-Memory_B_cells\|bone_marrow / Manually curated celltypes from each tissue	CD19 ATRNL1 RASGRP3 EML6	1.01e-05	184	33	4	ffc9eec123de34a4f17ed27fe4f0a1b3cb84697f
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CD19 FASLG GZMK	1.03e-05	185	33	4	c9ab7a3584d25f0ed73b20919c3dba00f502eac4
ToppCell	COVID-19-Fibroblasts-Pericytes\|COVID-19 / group, cell type (main and fine annotations)	NFASC MYO1B NRCAM JAG1	1.03e-05	185	33	4	4905adaeeffd353e089578e5ea614437dbe794e6
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 GIMAP8 ADAM23 RASGRP3	1.03e-05	185	33	4	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 EML5 NRCAM TMEFF2	1.03e-05	185	33	4	94d0f283d63d932f310cc5a17ea893d71ba60f5e
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CHL1 NFASC EML5 TMEFF2	1.05e-05	186	33	4	2fdd0a80ad31cf017aafcf5dcf760ebd786b98c1
ToppCell	Healthy_donor-B_memory\|World / disease group, cell group and cell class (v2)	CD19 ATRNL1 RASGRP3 EML6	1.08e-05	187	33	4	4f68e3243071a4549c80aff8bff32c6ad892ee7f
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GIMAP8 CD19 FASLG GZMK	1.08e-05	187	33	4	66cf67c76067e4ba8c09c110adfa0ccc0d1c5ee9
ToppCell	facs-MAT-Fat-18m-Lymphocytic-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CD19 FASLG GZMK	1.10e-05	188	33	4	6cd04603bf5ca4d23a31ebced7535999583e1265
ToppCell	facs-MAT-Fat-18m-Lymphocytic\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CD19 FASLG GZMK	1.10e-05	188	33	4	613d4484d8d00ed18e5061bd0957b6beef6be8dd
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1B NRCAM ADAM23 EML6	1.12e-05	189	33	4	bfc76a72b600d641c8fe58346e5d8986c34f3981
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	NFASC MYO1B NET1 JAG1	1.12e-05	189	33	4	f4865b7db16de15120504147a8016ac522ad242a
ToppCell	10x5'-GI_large-bowel-Lymphocytic_B-GC_B_(II)\|GI_large-bowel / Manually curated celltypes from each tissue	IGSF10 CD19 NET1 EML6	1.15e-05	190	33	4	fee64bacbb330d04dc1dc63909838f2c605d9f1f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1B NRCAM ADAM23 EML6	1.15e-05	190	33	4	b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1B NRCAM ADAM23 EML6	1.15e-05	190	33	4	078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCell	wk_08-11-Epithelial-PNS-SST+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CHL1 EML5 NRCAM TMEFF2	1.17e-05	191	33	4	df2bef74a54f4c23c99bd3b93225fd36bcd90723
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1B NRCAM ADAM23 EML6	1.19e-05	192	33	4	fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1B NRCAM ADAM23 EML6	1.19e-05	192	33	4	bae236c9f1fac77bce28d0a9cf090100d391ff77
ToppCell	COVID-19-kidney-CD-PC\|kidney / Disease (COVID-19 only), tissue and cell type	MYO1B NRCAM ADAM23 EML6	1.22e-05	193	33	4	738689d009e4b118d7ce3171a207294b95cbe78b
ToppCell	distal-Hematologic-Plasma-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	EML5 CD19 PLA2G2D RASGRP3	1.29e-05	196	33	4	8201aded3c7109fae5e6ca12bac2076acc7bf070
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRCAM ADAM23 ATRNL1 EML6	1.29e-05	196	33	4	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 NFASC NRCAM TMEFF2	1.29e-05	196	33	4	e874aa82a20bb59582c8cd7f8d30b2ed02903a85
ToppCell	distal-1-Hematologic-Plasma\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	EML5 CD19 PLA2G2D RASGRP3	1.32e-05	197	33	4	f5499bfa9dbc111f12563b7006bc45c2423ad0cd
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 EML5 NRCAM TMEFF2	1.32e-05	197	33	4	f7eaac1c321710a55e09ffb047a7db2baf7b7e28
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NRCAM CD19 RASGRP3 EML6	1.32e-05	197	33	4	0f489d26e4013d1b5a90559856ed2de32a0bb772
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 NFASC EML5 TMEFF2	1.32e-05	197	33	4	a07e1a9b95c9f8a09452cbfe5a9f06648f66e29e
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NRCAM CD19 ATRNL1 RASGRP3	1.35e-05	198	33	4	4aa4ae2571effcfb6eb6923f7173cd3e7e4af9ef
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRCAM ADAM23 ATRNL1 EML6	1.35e-05	198	33	4	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRCAM ADAM23 ATRNL1 EML6	1.35e-05	198	33	4	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRCAM ADAM23 ATRNL1 EML6	1.35e-05	198	33	4	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 NFASC EML5 TMEFF2	1.37e-05	199	33	4	ce8dbfd969b3b9c08e1c57c2bfd899818e878731
ToppCell	Macroglial-Oligodendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	NFASC RASGRP3 PCSK6 TMEFF2	1.40e-05	200	33	4	4dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCell	Macroglial-Oligodendrocytes-OPALIN--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	NFASC RASGRP3 PCSK6 TMEFF2	1.40e-05	200	33	4	26b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCell	severe-B_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHL1 MYO1B CD19 RASGRP3	1.40e-05	200	33	4	0e86f52b6e146d9bbc728d8fb176fc2b53696558
ToppCell	Macroglial-Oligodendrocytes-OPALIN---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	NFASC RASGRP3 PCSK6 TMEFF2	1.40e-05	200	33	4	1314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCell	Macroglial-Oligodendrocytes-OPALIN-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	NFASC RASGRP3 PCSK6 TMEFF2	1.40e-05	200	33	4	8b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCell	severe-B_naive\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHL1 MYO1B CD19 RASGRP3	1.40e-05	200	33	4	306df1f498ac2188eaf9f2a8d002bb73bdb9642d
ToppCell	Macroglial-Oligodendrocytes-OPALIN----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	NFASC RASGRP3 PCSK6 TMEFF2	1.40e-05	200	33	4	272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCell	Macroglial-Oligodendrocytes-OPALIN\|Macroglial / cells hierarchy compared to all cells using T-Statistic	NFASC RASGRP3 PCSK6 TMEFF2	1.40e-05	200	33	4	5f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCell	mild-B_naive\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHL1 MYO1B CD19 RASGRP3	1.40e-05	200	33	4	d0467cab6a42bf780aa49046bf3231ca161dc144
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a\|Striatum / BrainAtlas - Mouse McCarroll V32	TOMM70 CRHR1 GZMK	7.16e-05	109	33	3	e8e0f2c5f8c9e45f2b4d173569c94275eedfe432
ToppCell	(05)_Ciliated-(2)_48hpi\|(05)_Ciliated / shred by cell type and Timepoint	SGTB NRCAM ADAM23	1.05e-04	124	33	3	fc8cce8c1809edafbc4e69e501dd4f016f5dfc0b
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells-iNKT-MAIT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP8 FASLG GZMK	1.32e-04	134	33	3	92981dc68c1b3cdc53f9cf83386c47f0c6c98ae7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 IGSF10 SGTB	1.44e-04	138	33	3	2e46d546ad962aa0fde5b1c18c2a5370a4424e9f
ToppCell	Control-Fibroblasts-Mesothelial_FB\|Control / group, cell type (main and fine annotations)	NFASC NRCAM ATRNL1	1.47e-04	139	33	3	e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-T-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FASLG ADAM23 GZMK	1.47e-04	139	33	3	ecc2a6ecc27748c50885cd4f0ad8a8cd1252aee6
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_activate-7\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD19 RASGRP3 EML6	1.47e-04	139	33	3	693ca81f5831b63fe6148ac755631e09f67d0ebf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 IGSF10 SGTB	1.63e-04	144	33	3	163c591fedad2beb7f92531e6240e9554f90ea40
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NRCAM CD19 ATRNL1	1.63e-04	144	33	3	fca32b38d23fa4d213e553b929604a2796e9a929
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TOMM70 FASTKD5 DELE1	1.67e-04	145	33	3	c0894c738815ff54790caddb4bccfa1503fd555b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	IGSF10 ADAM23 GZMK	1.74e-04	147	33	3	9566398275cad79223db90ffe640830acf2db864
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC6A8 FASLG GZMK	1.74e-04	147	33	3	48d72b6770cd029dd299676e5d83e6ac62102049
ToppCell	Control-Lymphocytic_NKT-iNKT/MAIT-T-cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP8 ADAM23 GZMK	1.77e-04	148	33	3	003e10bf477984248211b99d75daa8f7dcdb12c8
ToppCell	facs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CHL1 NFASC PLA2G2D	1.77e-04	148	33	3	5983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD19 RASGRP3 EML6	1.81e-04	149	33	3	2cd860b96ed4be4d26844085d464961c1418054a
ToppCell	COVID-19_Severe-B_cell\|World / disease group, cell group and cell class	CHL1 MYO1B CD19	1.81e-04	149	33	3	9a9fcbf7e8a6811958f3fd2d36315e19ab2b1127
ToppCell	facs-GAT-Fat-3m-Lymphocytic-NK_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 GIMAP8 FASLG	1.88e-04	151	33	3	3d07b79ecbcfad13116f0f2b039bd181a7ffe853
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FASLG PCSK6 GZMK	1.88e-04	151	33	3	09405a450af3ea246d9685a6d3137dfaec80e9bf
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MEIOC RASGRP3 GZMK	1.91e-04	152	33	3	5adcdf93fd3ca066402aaaf308c363e4648f871d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC NET1 JAG1	1.91e-04	152	33	3	0cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC NET1 JAG1	1.91e-04	152	33	3	ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 FASLG CDON	2.03e-04	155	33	3	c58a5fb8d853f12204e961d633e83452eb12a659
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|356C / Donor, Lineage, Cell class and subclass (all cells)	CHL1 PCSK6 CDON	2.03e-04	155	33	3	e1a20e88b9c0eaf7ca7004acc0eda096d1588563
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 FASLG CDON	2.03e-04	155	33	3	9cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 FASLG GZMK	2.07e-04	156	33	3	39aa3adbee9f04cdc0055487d393edfa515e062b
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 FASLG GZMK	2.07e-04	156	33	3	a09e3aefe78d63ad5428ad48c6f83e547eb819f6
ToppCell	COVID-19-lung-Mesothelial\|lung / Disease (COVID-19 only), tissue and cell type	ATRNL1 TMEFF2 CDON	2.07e-04	156	33	3	e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCell	droplet-Lung-nan-3m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP8 CD19 FASLG	2.11e-04	157	33	3	b337937a88f62030114a28d70a63168417672767
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYO1B NET1 CRHR1	2.11e-04	157	33	3	5aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCell	COVID-naiveBc-\|COVID / Condition, Cell_class and T cell subcluster	NRCAM CD19 EML6	2.19e-04	159	33	3	4e6783b0f69c0c70150f9f3594881dc1bac7038a
ToppCell	COVID-naiveBc\|COVID / Condition, Cell_class and T cell subcluster	NRCAM CD19 EML6	2.19e-04	159	33	3	52cd36b4412f69a935b3f76da96c166a9481eb0c
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	NFASC JAG1 GZMK	2.23e-04	160	33	3	fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 NFASC PLA2G2D	2.23e-04	160	33	3	f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD19 RASGRP3 EML6	2.23e-04	160	33	3	7ad065337ac802de52c15ee715f6b78a3eed0cef
ToppCell	mild_COVID-19_(asymptomatic)-B_intermediate\|World / disease group, cell group and cell class (v2)	MYO1B CD19 RASGRP3	2.23e-04	160	33	3	6722934e153b72039c3c4308557d0ef879a30638
ToppCell	normal-na-Lymphocytic_B-B_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CHL1 CD19 RASGRP3	2.31e-04	162	33	3	ae292318d339305932457bb0e91430594f7a3dfa
ToppCell	facs-Marrow-KLS-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 RASGRP3 JAG1	2.35e-04	163	33	3	b83a35c4426d66b5734a98fa6c72b345fe462030
ToppCell	TCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Seminoma-_NOS-5\|TCGA-Testes / Sample_Type by Project: Shred V9	NRCAM ADAM23 EML6	2.35e-04	163	33	3	80bc3732afd8501938753120b8403098c7c5e928
Drug	alpha-chaconine	SGTB SGTA JAG1	1.53e-06	16	33	3	CID000104750
Drug	Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; PC3; HT_HG-U133A	NFASC ADAM23 ATRNL1 CRHR1 PCSK6	8.34e-06	194	33	5	3676_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A	NRCAM ADAM23 ALG12 JAG1 GZMK	8.76e-06	196	33	5	4526_UP
Drug	Buflomedil hydrochloride [35543-24-9]; Up 200; 11.6uM; PC3; HT_HG-U133A	NFASC NRCAM FASLG CRHR1 PCSK6	9.21e-06	198	33	5	4258_UP
Drug	Nialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A	CHL1 ADAM23 MUC5AC CRHR1 PCSK6	9.21e-06	198	33	5	3790_UP
Disease	MASA syndrome (implicated_via_orthology)	CHL1 NFASC NRCAM	4.45e-08	7	33	3	DOID:0060246 (implicated_via_orthology)
Disease	biliary tract benign neoplasm (is_marker_for)	FASLG MUC5AC	2.54e-05	7	33	2	DOID:0050625 (is_marker_for)
Disease	gastric ulcer (biomarker_via_orthology)	FASLG MUC5AC	2.51e-04	21	33	2	DOID:10808 (biomarker_via_orthology)
Disease	epilepsy (implicated_via_orthology)	CHL1 NFASC NRCAM	7.99e-04	163	33	3	DOID:1826 (implicated_via_orthology)
Disease	rhinitis (is_marker_for)	MUC5AC CRHR1	1.22e-03	46	33	2	DOID:4483 (is_marker_for)
Disease	pulmonary fibrosis (biomarker_via_orthology)	MUC5AC JAG1	1.44e-03	50	33	2	DOID:3770 (biomarker_via_orthology)
Disease	severe acute respiratory syndrome, COVID-19	NFASC SGTB ADAM23 PCSK6	1.50e-03	447	33	4	EFO_0000694, MONDO_0100096
Disease	pancreatic ductal carcinoma (is_marker_for)	FASLG MUC5AC	2.13e-03	61	33	2	DOID:3587 (is_marker_for)
Disease	cystic fibrosis (is_marker_for)	FASLG MUC5AC	2.20e-03	62	33	2	DOID:1485 (is_marker_for)
Disease	Mammary Neoplasms, Human	NRCAM CRHR1 JAG1 APOBEC3A	2.69e-03	525	33	4	C1257931
Disease	Mammary Carcinoma, Human	NRCAM CRHR1 JAG1 APOBEC3A	2.69e-03	525	33	4	C4704874
Disease	Nonorganic psychosis	CRHR1 APOBEC3A	2.72e-03	69	33	2	C0349204
Disease	Mammary Neoplasms	NRCAM CRHR1 JAG1 APOBEC3A	2.73e-03	527	33	4	C1458155
Disease	Schizophrenia	CHL1 NFASC FASTKD5 EML5 JAG1	2.81e-03	883	33	5	C0036341
Disease	Breast Carcinoma	NRCAM CRHR1 JAG1 APOBEC3A	2.94e-03	538	33	4	C0678222
Disease	multiple sclerosis (is_implicated_in)	FASLG JAG1	3.03e-03	73	33	2	DOID:2377 (is_implicated_in)
Disease	urinary bladder cancer (is_implicated_in)	FASLG TMEFF2	3.28e-03	76	33	2	DOID:11054 (is_implicated_in)
Disease	sudden cardiac arrest	CHL1 TMEFF2	3.90e-03	83	33	2	EFO_0004278
Disease	neuroimaging measurement, brain volume measurement	SGTB RASGRP3 JAG1	3.96e-03	286	33	3	EFO_0004346, EFO_0006930
Disease	thalamus volume	NFASC SGTB	4.09e-03	85	33	2	EFO_0006935

Protein segments in the cluster

Peptide	Gene	Start	Entry
KQDGYACNQNQGRCY	ADAM23	586	O75077
NFNNGIGRHKTYLCY	APOBEC3A	21	P31941
LSRKLCNSQSYYNGD	GZMK	176	P49863
NITAARGCSYLLNNY	ALG12	321	Q9BV10
NAYRGYCSNQLAAKA	NET1	261	Q7Z628
SYQDKGNYRCTASNF	CHL1	301	O00533
QCNASNEYGYLLANA	NRCAM	431	Q92823
ASANNSYCIVGIAYN	PCSK6	256	P29122
CRNREQASGLCYNYQ	MUC5AC	1456	P98088
YQCFARNKFGTALSN	NFASC	116	O94856
KLAVQFTNRNQYCYG	FASTKD5	696	Q7L8L6
ATAYDRGNYICKAQN	IGSF10	2496	Q6WRI0
ATAQDAGKYYCHRGN	CD19	251	P15391
LLGYYQCLANNSIGA	CDON	91	Q4KMG0
YGLIQKCKNRYSAFN	GIMAP8	386	Q8ND71
NAKLYCYNLSGNLAS	ATRNL1	771	Q5VV63
RYNTTNNGYRECLAN	CRHR1	76	P34998
GHQCRNNLYYTAAKE	EML5	21	Q05BV3
GHQCRNNLYYTAGKE	EML6	21	Q6ZMW3
AAARGYSKAQYNAGL	DELE1	271	Q14154
NGAQCYNRASDYFCK	JAG1	536	P78504
NGFCDNYSAQKYGII	MEIOC	586	A2RUB1
NPANAVYFCNRAAAY	SGTA	121	O43765
VYFCNRAAAYSKLGN	SGTA	126	O43765
NGESYQNECYLRQAA	TMEFF2	106	Q9UIK5
ELVSSNGNYCNYRKA	RASGRP3	276	Q8IV61
NGNYCNYRKAFADCD	RASGRP3	281	Q8IV61
ALGSYNRFNNNCYKD	SLC6A8	326	P48029
YRYNFSQGNIHCSDK	PLA2G2D	86	Q9UNK4
KCFALYRQAYTGNNS	TOMM70	441	O94826
VYSKVYFRGQSCNNL	FASLG	191	P48023
PNNAVYYCNRAAAQS	SGTB	116	Q96EQ0
AYLKGNEAYSGNARN	ARHGAP21	181	Q5T5U3
SGHYIAYCRNNLNNL	USP33	671	Q8TEY7
NVAQAYYARDALAKN	MYO1B	341	O43795