Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainTIL

TECTA SSPOP

4.20e-0412482PF01826
DomainC8

TECTA SSPOP

4.20e-0412482PF08742
DomainUnchr_dom_Cys-rich

TECTA SSPOP

4.95e-0413482IPR014853
DomainC8

TECTA SSPOP

4.95e-0413482SM00832
DomainTIL_dom

TECTA SSPOP

5.77e-0414482IPR002919
DomainVWD

TECTA SSPOP

7.58e-0416482SM00216
DomainVWF_type-D

TECTA SSPOP

7.58e-0416482IPR001846
DomainVWFD

TECTA SSPOP

7.58e-0416482PS51233
DomainVWD

TECTA SSPOP

7.58e-0416482PF00094
DomainVWC_out

TECTA SSPOP

1.08e-0319482SM00215
DomainARM-type_fold

DOCK3 CUL9 ZYG11B URB1 XPO5

1.73e-03339485IPR016024
DomainVWC

TECTA SSPOP

4.29e-0338482SM00214
DomainVWFC_2

TECTA SSPOP

4.29e-0338482PS50184
DomainVWF_dom

TECTA SSPOP

5.22e-0342482IPR001007
DomainC2

CPNE9 WWC3 RASA1

5.80e-03142483PS50004
Domain-

CPNE9 WWC3 RASA1

6.50e-031484832.60.40.150
DomainC2_dom

CPNE9 WWC3 RASA1

8.61e-03164483IPR000008
DomainDH_1

AKAP13 PLEKHG3

1.14e-0263482PS00741
DomainUSP_CS

USP36 USP10

1.25e-0266482IPR018200
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CXXC5 NLRC5 WASHC3 USP10 AKAP13 MIA3 TECTA SPPL2B RASA1 SSPOP PLEKHG3 CASZ1 TERF2IP NOTCH3 TRPM2

8.00e-101489481528611215
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MED14 DOCK3 NAV2 NLRC5 CUL9 AKAP13 URB1 SETD1B SPPL2B SPEN CASZ1

2.44e-071105481135748872
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

ZNF8 NAV2 USP10 AKAP13 TACC2 SPEN ZCCHC8 TERF2IP

4.11e-0750348816964243
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CYC1 MED14 USP36 CXXC5 USP10 URB1 SPEN ZCCHC8 PLEKHG3 CASZ1 TERF2IP RAD21

6.39e-071497481231527615
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

MED14 DOCK3 CUL9 URB1 SPEN NOTCH3

6.01e-0632948617474147
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

USP36 CXXC5 URB1 DEAF1 SPEN ZCCHC8 CASZ1 TERF2IP RAD21 EFTUD2

8.84e-061294481030804502
Pubmed

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.

MED14 AKAP13 SETD1B SPEN RAD21

4.43e-0528348518854154
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MED14 USP10 DEAF1 SPEN ZCCHC8 TERF2IP EFTUD2

8.76e-0577448715302935
Pubmed

The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.

SPEN RAD21 EFTUD2

2.17e-048448326299517
Pubmed

Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling.

USP10 RAD21 EFTUD2

2.41e-048748324169447
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CUL9 ZYG11B SETD1B SPEN XPO5

2.42e-0440748512693553
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CUL9 URB1 SPEN XPO5 ZCCHC8 RAD21

2.69e-0465348622586326
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

USP36 USP10 TACC2 ZCCHC8 UBFD1 RAD21 EFTUD2

2.78e-0493448733916271
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

USP36 USP10 URB1 XPO5 ZCCHC8 RAD21 EFTUD2

3.92e-0498948736424410
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

URB1 SSPOP PLEKHG3

4.19e-041054839628581
Pubmed

Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.

NAV2 USP10 SETD1B TECTA

4.39e-0425748430945288
Pubmed

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.

USP36 FIBP TERF2IP EFTUD2

4.52e-0425948430404004
Pubmed

A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.

CUL9 EFTUD2

5.05e-042448233705438
Pubmed

USP37 is a SNAI1 deubiquitinase.

USP36 USP10

5.05e-042448231911859
Pubmed

Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.

FIBP MYL9

5.93e-042648223382103
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MED14 USP10 TACC2 URB1 TERF2IP RAD21

5.96e-0475948635915203
Pubmed

Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.

MED14 SETD1B TERF2IP

6.04e-0411948323508102
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

CUL9 SPEN XPO5 ZCCHC8

6.22e-0428248423667531
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

PEX19 USP10 URB1 MYL9 XPO5 ZCCHC8 PLEKHG3 EFTUD2

7.30e-04144048830833792
Pubmed

SARS-CoV-2 nucleocapsid protein interacts with immunoregulators and stress granules and phase separates to form liquid droplets.

USP10 EFTUD2

7.92e-043048234780058
Pubmed

Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.

CXXC5 RAD21

8.45e-043148227321927
Pubmed

Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin.

USP36 USP10

9.58e-043348230323974
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

CYC1 MED14 XPO5 RAD21 EFTUD2

1.03e-0356048535241646
Pubmed

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.

USP36 FIBP USP10

1.11e-0314748329576527
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

CUL9 MYL9 SPEN CASZ1 HSD17B8 NOTCH3

1.12e-0385748625609649
Pubmed

Tagging genes with cassette-exchange sites.

PEX19 NAV2 AKAP13 XPO5

1.18e-0333548415741177
Pubmed

ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2.

USP10 TERF2IP

1.27e-033848230629181
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CUL9 TACC2 SETD1B SPEN ZCCHC8

1.28e-0358848538580884
InteractionAZU1 interactions

USP36 ZYG11B RAD21

2.17e-0523483int:AZU1
InteractionHACD3 interactions

PEX19 DOCK3 SPPL2B ADIPOR2 EFTUD2 NMRAL1

2.27e-05242486int:HACD3
InteractionTOP3B interactions

MED14 DOCK3 NAV2 NLRC5 CUL9 USP10 AKAP13 URB1 SETD1B SPPL2B SPEN XPO5 CASZ1

2.71e-0514704813int:TOP3B
GeneFamilyUbiquitin specific peptidases

USP36 USP10

5.25e-0356352366
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AKAP13 PLEKHG3

7.23e-0366352722
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AKAP13 RASA1 PLEKHG3

7.30e-03206353682
GeneFamilyShort chain dehydrogenase/reductase superfamily

HSD17B8 NMRAL1

9.49e-0376352743
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NLRC5 DIPK1C PLEKHG3 NOTCH3 BGN

1.12e-06171485285533ca2a6a411773313166bee35542f34d1a3c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXXC5 DIPK1C PLEKHG3 NOTCH3 BGN

1.74e-061874856820bfbe552ea5e62cfe699687b051a17d9fda61
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK3 TACC2 MYL9 NOTCH3 BGN

2.03e-06193485000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYL9 PLEKHG3 NOTCH3 BGN

2.53e-0515848408806240228c5b780f5aef92ce2c278ae4d797cc
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYL9 PLEKHG3 NOTCH3 BGN

2.53e-05158484496b6988f7b3439968351840ae22f56ffa1643f1
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell-SMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYL9 PLEKHG3 NOTCH3 BGN

2.53e-051584845b3d30f92b619f14a7b48502170000fa5783358a
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYL9 PLEKHG3 NOTCH3 BGN

3.68e-05174484778e0317c0c63fa4efd74114feb760975b819d92
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DIPK1C MYL9 NOTCH3 BGN

4.02e-051784848f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF8 NAV2 MYL9 NOTCH3

4.20e-05180484455d1e3ccf2ab609954f3b870e8f514ddca735f4
ToppCellfacs-Heart-LV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP PLEKHG3 NOTCH3 EFTUD2

4.29e-051814841db1eb7d330a7e5090994007ae287e11f0a74450
ToppCellfacs-Heart-LV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP PLEKHG3 NOTCH3 EFTUD2

4.29e-0518148406174ce9240c9261c0f51a1b0d875335d60722e5
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)|Cerebellum / BrainAtlas - Mouse McCarroll V32

MYL9 PLEKHG3 NOTCH3 BGN

4.39e-05182484da61e7cb2537c567968d8bd8baf537ecdff0ab18
ToppCellCerebellum-Endothelial-MURAL|Cerebellum / BrainAtlas - Mouse McCarroll V32

MYL9 PLEKHG3 NOTCH3 BGN

4.39e-05182484b2f03f61aebb5920595fed8b9d6799a09353419b
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYL9 PLEKHG3 NOTCH3 BGN

4.48e-05183484b4f29dd3994009bb5eb769d36d95886664e7f87d
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 MYL9 NOTCH3 BGN

4.48e-051834848de4b616a06be03e1cb6ae6a9ce6bf06485629d3
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

MYL9 PLEKHG3 NOTCH3 BGN

4.87e-0518748462759efb660179402fb574ce5701c89a2e17bcfe
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK3 NAV2 TACC2 MYL9

4.98e-051884844d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK3 NAV2 TACC2 MYL9

4.98e-05188484f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NAV2 MYL9 CASZ1 BGN

4.98e-051884843004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYL9 CASZ1 NOTCH3 BGN

5.08e-05189484f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DIPK1C MYL9 NOTCH3 BGN

5.08e-051894841ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 MYL9 NOTCH3 BGN

5.08e-051894847ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CXXC5 MYL9 NOTCH3 BGN

5.18e-051904842ab604d35456beba71c25511e0f819000e6642d2
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 MYL9 NOTCH3 BGN

5.29e-051914847853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYL9 PLEKHG3 NOTCH3 BGN

5.29e-051914849431ffd6b758f756609d9057de2023596e22b5d4
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 MYL9 NOTCH3 BGN

5.29e-0519148408042952431ca1a6fd7dfc13f36eb28643979598
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXXC5 DIPK1C NOTCH3 BGN

5.40e-0519248471863f18a82394ed9f8e5ec8a4017215382a8284
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 MYL9 NOTCH3 BGN

5.40e-05192484992d08092edbc68c47b945deb8708379738c239a
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYL9 PLEKHG3 NOTCH3 BGN

5.40e-051924845000440dc1ed17e7474d340921bdff945646f27e
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYL9 PLEKHG3 NOTCH3 BGN

5.51e-05193484469a7f1c2ff7137cc5a064464456911f67f92e70
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYL9 PLEKHG3 NOTCH3 BGN

5.51e-05193484323d1f3f4fbeb93ba857fc135d8aa0b897f98ac5
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TACC2 MYL9 NOTCH3 BGN

5.62e-05194484aaecde88bd54134a938e76cdf059c1c2653e4e77
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TACC2 MYL9 NOTCH3 BGN

5.62e-0519448467f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYL9 PLEKHG3 NOTCH3 BGN

5.73e-05195484c51b1bee79e77aa2ac444a4883ef533c0095eaad
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TACC2 MYL9 NOTCH3 BGN

5.73e-0519548456e7cd980f8fc2dae842e6a7bd919d4b41cebbbb
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYL9 PLEKHG3 NOTCH3 BGN

5.73e-0519548443d372373367b71243c6ea958aedccde4478618f
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 AKAP13 TACC2 CASZ1

5.73e-0519548475fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TACC2 MYL9 NOTCH3 BGN

5.73e-05195484a28a504c69bc4dda7de023e1b4ea4f62390b158e
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TACC2 MYL9 NOTCH3 BGN

5.85e-051964844740ef6e428f1ccc81fc98c3b868afd38ce60535
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MYL9 PLEKHG3 NOTCH3 BGN

5.97e-05197484b67ffd27d386c8186ef71ecdac96a462504507f0
ToppCellIPF-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

USP36 NAV2 AKAP13 TACC2

6.08e-05198484b8bd1ba268480f54451648e01631b615a3401144
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TACC2 MYL9 NOTCH3 BGN

6.08e-05198484c9c96066c7fa897b583657f0b77ea093920ae9ba
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MYL9 TECTA NOTCH3 BGN

6.20e-051994848ff0fdcbe9661b013913731ec8b53d84836ca865
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

MYL9 PLEKHG3 NOTCH3 BGN

6.33e-052004840c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TACC2 PLEKHG3 NOTCH3 BGN

6.33e-052004849169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MYL9 PLEKHG3 NOTCH3 BGN

6.33e-0520048494f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TACC2 MIA3 CASZ1 ENTPD8

6.33e-05200484c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCelldistal-1-mesenchymal|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TMEM176A MYL9 NOTCH3 BGN

6.33e-052004847623f82bd85a0ff7e2097e9281551208dfc602a8
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TACC2 PLEKHG3 NOTCH3 BGN

6.33e-05200484a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TMEM176A MYL9 NOTCH3 BGN

6.33e-05200484fc2fc3bfcf1ad9bfb9fe07bbed8068126930bee6
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

URB1 MIA3 CASZ1 ENTPD8

6.33e-05200484ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright|ICU-NoSEP / Disease, condition lineage and cell class

MED14 MYL9 RASA1 CASZ1

6.33e-05200484c2df917900872453ea17a39928e39d071a6d3339
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYL9 PLEKHG3 NOTCH3 BGN

6.33e-05200484522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYL9 NOTCH3 BGN

3.08e-04122483c16110934172f174f4aefe14b81abce8514b30f0
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell-Peri|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYL9 NOTCH3 BGN

3.08e-04122483006ac4f6807e688554d36557d29d5e5a0bc3c36f
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYL9 NOTCH3 BGN

3.08e-04122483f3d9a5893fdee3562880fb6fc132b88169a7d997
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CXXC5 EFCC1 SSPOP

3.71e-041304836c6a8b77af08b30b424d4f5def37315d3c6e28b2
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_fibroblast-mesenchymal_B|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CXXC5 EFCC1 SSPOP

3.71e-041304830706092f6b466585b3b4808b3b982a122d66cfcf
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

NLRC5 AKAP13 BGN

4.14e-04135483ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-matrix_-_mature_3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ZNF8 TACC2 HSD17B8

4.32e-041374839bfdbc102cdd861996b3c4eac35b606be8af97eb
ToppCellfacs-Skin-Anagen-24m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV2 NLRC5 NOTCH3

4.51e-04139483da8874d441b8e69c94bad771635f378ddafb49fe
ToppCellControl-NK|World / Disease group and Cell class

DOCK3 CXXC5 NAV2

4.90e-04143483fe08adc9472dfd4242497d6c614d0490713261da
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYL9 NOTCH3 BGN

4.90e-041434839bfb3674c8f011b9cf928b522777b8d54478db8d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-VLMC-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYL9 NOTCH3 BGN

5.10e-041454837d90d95dc80b7d6230bc24ef6a524a8bb243a65e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-VLMC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYL9 NOTCH3 BGN

5.10e-0414548318e958b7435fb4d7384f4ad5ab31d7a464a55eb9
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CPNE9 NOTCH3 BGN

5.20e-041464832ac9b487a7991fdc15444aeb93533030e09825bb
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TMEM176A SSPOP CASZ1

5.20e-04146483cffa91d76606f74553d81150adbb23b003746316
ToppCell368C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

MYL9 NOTCH3 BGN

5.85e-041524833a1414ba6a4972698c3262a00b124428835c35cb
ToppCell368C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

MYL9 NOTCH3 BGN

5.85e-04152483ee7855d76a49d07a032677a4dc83aa6116d50518
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TMEM176A SSPOP CASZ1

5.96e-04153483e7d20c88466ff81db613869cf7a6a4bb95fd6c2f
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

TACC2 MYL9 CASZ1

5.96e-04153483ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYL9 PLEKHG3 BGN

6.19e-04155483d8b5145258f075b15080f8739f537f48dd22225e
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYL9 PLEKHG3 BGN

6.19e-04155483ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYL9 PLEKHG3 BGN

6.19e-041554830f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Teffector/EM_CD4|GI_large-bowel / Manually curated celltypes from each tissue

CUL9 ZYG11B PLEKHG3

6.31e-0415648301f2c0c6a936dfb59bc727feef428a906ad2a80b
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE9 PLEKHG3 TRPM2

6.43e-041574830ad242320ada7bcb9e29548d3050bf4fd3a07115
ToppCellfacs-Lung-Endomucin-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE9 PLEKHG3 TRPM2

6.43e-04157483fe4c9556806203e57522d1986754ebe5a20aa2de
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYL9 NOTCH3 BGN

6.54e-0415848332c95c1bc9e50fccd6d06e828f29258fc5e568cb
ToppCellControl-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

MYL9 NOTCH3 BGN

6.67e-041594836f50c381cd8a26a5a90bf0ce909713cea96910d7
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MYL9 NOTCH3 BGN

6.67e-041594837cda111bb98f1241989e49d490bdf51a712ea589
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

PLEKHG3 NOTCH3 BGN

6.79e-04160483fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-3|TCGA-Adrenal / Sample_Type by Project: Shred V9

EFCC1 NOTCH3 BGN

6.91e-0416148352239a887799362256ecd7e740b716b88ed59a62
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYL9 NOTCH3 BGN

7.04e-04162483c5eee02836efde2108534679850c28d2b2cfce3f
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYL9 PLEKHG3 BGN

7.29e-041644839eed945e9b0c1ee5fc62724ac2bbbed4267b0678
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYL9 PLEKHG3 BGN

7.29e-04164483f510f20e37e31b486cdd0e3f597ce4ff00877c5d
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYL9 PLEKHG3 BGN

7.29e-041644835c932a462cbf81d029c8d11ec3aea3191529527b
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

AKAP13 TACC2 WWC3

7.29e-04164483beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

AKAP13 TACC2 WWC3

7.29e-04164483d005cfd821b87548b075120bffe65a0be9860463
ToppCell15-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

DOCK3 TACC2 CASZ1

7.42e-04165483531804467601e1ee1f771cffa21501f6d464ae10
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYL9 NOTCH3 BGN

7.42e-041654839de841c1c95967c562720feba930246debc626fd
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYL9 NOTCH3 BGN

7.42e-04165483a612a7d3a5415ecacc3df8fbff0ce498f982aad0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYL9 NOTCH3 BGN

7.42e-04165483cdc94a640ec01c6892521bcd6f0ee0a66ff23866
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CXXC5 MYL9 BGN

7.55e-04166483dc443a3327dc8f9a0d808c3c6e06b0834d45f5c2
ToppCellICU-NoSEP-Lymphocyte-T_NK-NK_CD56bright|ICU-NoSEP / Disease, Lineage and Cell Type

MED14 MYL9 CASZ1

7.68e-04167483f4f188a8efca8cdd0ecfb857fe4538c10847eadd
ToppCellControl-NK|Control / Disease group and Cell class

DOCK3 CXXC5 NAV2

7.82e-04168483683d389c8a1e791bfc773e63148115a21a6566db
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MYL9 NOTCH3 BGN

7.82e-04168483b220e732eb7b204fc263a9f2e8ddae6bf9fa98f4
ToppCellSubstantia_nigra-Endothelial-MURAL|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MYL9 NOTCH3 BGN

7.82e-04168483271a81c59a9a75bac6107c68fead03e7f35bc192
ToppCellPosterior_cortex-Endothelial-MURAL|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MYL9 NOTCH3 BGN

7.95e-041694830ae65daf092396b71f790b65c7a2feed90397417
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MYL9 NOTCH3 BGN

7.95e-041694838cd70ce27b1cecb83f8a376230e7ef41b079b124
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

MYL9 NOTCH3 BGN

8.09e-04170483d69c0ea4cb6b204f19d0a5d2164afb42184779ac
DiseaseMalignant neoplasm of breast

MED14 NLRC5 TACC2 TECTA SPEN HSD17B8 NOTCH3 BGN

2.29e-041074468C0006142
Diseasebrain cancer (implicated_via_orthology)

NOTCH3 RAD21

7.55e-0426462DOID:1319 (implicated_via_orthology)
Diseasecholesteryl ester 20:4 measurement

NAV2 CASZ1

2.16e-0344462EFO_0010348
Diseasehepatocellular carcinoma (is_implicated_in)

XPO5 RAD21 EFTUD2

2.84e-03181463DOID:684 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
GPPGLMDAETDECMD

CASZ1

1341

Q86V15
PDTAGEMEHGLMNPD

AKAP13

476

Q12802
DGPNEDGEMFMRPGK

CYC1

156

P08574
MEPVSTGAEAGMEGA

EFCC1

1

Q9HA90
DEAPQEDEGFMGMSP

ADIPOR2

66

Q86V24
MMAAEAGSEEGGPVT

RASA1

1

P20936
AGVMLPEQPAHDDMD

RAD21

251

O60216
GDVPMDGMSVSDLGP

NMRAL1

181

Q9HBL8
PEEMLVGALDMGGAS

ENTPD8

196

Q5MY95
GAHTMEDLEGMAPDP

C9orf131

256

Q5VYM1
TDEYLEGMMSEAPGP

MYL9

66

P24844
DGPFMMNDEEASGAD

BGN

31

P21810
MALTPPQGDADADGM

NOTCH3

1766

Q9UM47
PLMSEAGAGLPDMEA

CXXC5

181

Q7LFL8
PAEAAMVHMLGFDGP

NLRC5

356

Q86WI3
DDNPPSPIGGDMMDS

MED14

981

O60244
GMDEGDGEGNILPIM

PEX19

161

P40855
VMLGDGSMGDAPEDL

DOCK3

1696

Q8IZD9
AEPGHMDMGAEALPG

DEAF1

71

O75398
MDMGAEALPGPDEAA

DEAF1

76

O75398
MIPMGHLGDPEDVAD

HSD17B8

221

Q92506
VGPAMFEAMEELDGD

CPNE9

461

Q8IYJ1
PRDPGGLDEVAMGEM

CUL9

101

Q8IWT3
GEGGQDMPEAELLLM

DIPK1C

136

Q0P6D2
GADRSDMDDDMDPTP

KRBA2

461

Q6ZNG9
GEAPTDPDSQMDDMD

FIBP

216

O43427
EDDFMEPGGGLAMLA

SSPOP

331

A2VEC9
MGTADSDEMAPEAPQ

TMEM176A

1

Q96HP8
PLEEGLGGAMEEMQP

MIA3

1046

Q5JRA6
LLGMDPPGDMVDFVA

PLEKHG3

551

A1L390
GDEMDLEGISMDAPG

NAV2

871

Q8IVL1
GEDMEISDDEMPSAP

SETD1B

636

Q9UPS6
PGEAEEMADPELMAS

URB1

2036

O60287
GNPDDDLEMPMGLLA

TECTA

1246

O75443
MPEDQAGAAMEEASP

ZYG11B

1

Q9C0D3
APDGMEEPGMDTEAE

UBFD1

6

O14562
PADMELDSDMEVPHG

ZCCHC8

441

Q6NZY4
ADPDKEAAMMPAGVE

SPEN

1706

Q96T58
EAAMMPAGVEEGSSG

SPEN

1711

Q96T58
MIGDGATDMEACPPA

PSPH

176

P78330
KDAAAMDPMGDTLEP

TRPM2

1281

O94759
SEEMGAGAPMREPGS

SPPL2B

556

Q8TCT7
SSAPPADGDDEEMMA

XPO5

986

Q9HAV4
AAGETEGSMERMGEP

TACC2

1366

O95359
MDPEDEGVAGVMSVG

ZNF8

1

P17098
AEDAEFMGDMPPSVT

USP10

191

Q14694
LGEAMSDCDPDGPLM

EFTUD2

461

Q15029
MDEDGLPLMGSGIDL

WASHC3

1

Q9Y3C0
MGDEDLPGMAALQPH

WWC3

506

Q9ULE0
MGDGDPEAMEESPRK

USP36

941

Q9P275
MAEAMDLGKDPNGPT

TERF2IP

1

Q9NYB0