Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	poly(U) RNA binding	DIS3L2 PABPC3 PABPC1 HNRNPH1	5.28e-06	34	68	4	GO:0008266
GeneOntologyMolecularFunction	poly-pyrimidine tract binding	DIS3L2 PABPC3 PABPC1 HNRNPH1	9.25e-06	39	68	4	GO:0008187
GeneOntologyMolecularFunction	protein tyrosine phosphatase activity	PALD1 PTPRF PTPRJ PTPRU	4.22e-04	103	68	4	GO:0004725
GeneOntologyMolecularFunction	single-stranded RNA binding	DIS3L2 PABPC3 PABPC1 HNRNPH1	5.60e-04	111	68	4	GO:0003727
GeneOntologyCellularComponent	mCRD-mediated mRNA stability complex	PABPC3 PABPC1	1.51e-04	6	67	2	GO:0106002
GeneOntologyCellularComponent	catalytic step 2 spliceosome	PABPC3 DHX35 PABPC1 HNRNPH1	2.67e-04	97	67	4	GO:0071013
GeneOntologyCellularComponent	postsynapse	TNIK ABLIM1 PTPRF ATAD1 MTOR PLEKHA5 ZZEF1 LRRC4 MUSK HNRNPH1 HNRNPH2	3.63e-04	1018	67	11	GO:0098794
GeneOntologyCellularComponent	postsynaptic density	TNIK ABLIM1 PTPRF PLEKHA5 LRRC4 HNRNPH1 HNRNPH2	5.92e-04	451	67	7	GO:0014069
GeneOntologyCellularComponent	asymmetric synapse	TNIK ABLIM1 PTPRF PLEKHA5 LRRC4 HNRNPH1 HNRNPH2	8.23e-04	477	67	7	GO:0032279
GeneOntologyCellularComponent	postsynaptic specialization	TNIK ABLIM1 PTPRF PLEKHA5 LRRC4 HNRNPH1 HNRNPH2	1.12e-03	503	67	7	GO:0099572
Domain	zf-RNPHF	HNRNPH1 HNRNPH2	3.79e-05	3	67	2	PF08080
Domain	Znf_CHHC	HNRNPH1 HNRNPH2	3.79e-05	3	67	2	IPR012996
Domain	PTPc_motif	PALD1 PTPRF PTPRJ PTPRU	5.93e-05	59	67	4	SM00404
Domain	Tyr_Pase_cat	PALD1 PTPRF PTPRJ PTPRU	5.93e-05	59	67	4	IPR003595
Domain	-	KLHL5 KLHL24 KLHL4	1.21e-04	27	67	3	2.130.10.80
Domain	PolyA	PABPC3 PABPC1	1.26e-04	5	67	2	SM00517
Domain	-	PABPC3 PABPC1	1.26e-04	5	67	2	1.10.1900.10
Domain	PABP	PABPC3 PABPC1	1.26e-04	5	67	2	PF00658
Domain	PABC	PABPC3 PABPC1	1.26e-04	5	67	2	PS51309
Domain	PABP_1234	PABPC3 PABPC1	1.26e-04	5	67	2	IPR006515
Domain	PABP_HYD	PABPC3 PABPC1	1.26e-04	5	67	2	IPR002004
Domain	Gal_Oxidase_b-propeller	KLHL5 KLHL24 KLHL4	2.44e-04	34	67	3	IPR015916
Domain	PTPc	PTPRF PTPRJ PTPRU	2.89e-04	36	67	3	SM00194
Domain	-	PALD1 PTPRF PTPRJ PTPRU	3.33e-04	92	67	4	3.90.190.10
Domain	TYR_PHOSPHATASE_PTP	PTPRF PTPRJ PTPRU	3.68e-04	39	67	3	PS50055
Domain	PTPase_domain	PTPRF PTPRJ PTPRU	4.27e-04	41	67	3	IPR000242
Domain	Y_phosphatase	PTPRF PTPRJ PTPRU	4.27e-04	41	67	3	PF00102
Domain	Prot-tyrosine_phosphatase-like	PALD1 PTPRF PTPRJ PTPRU	4.41e-04	99	67	4	IPR029021
Domain	Kelch	KLHL5 KLHL24 KLHL4	1.18e-03	58	67	3	SM00612
Domain	Gal_Oxase/kelch_b-propeller	KLHL5 KLHL24 KLHL4	1.24e-03	59	67	3	IPR011043
Domain	BACK	KLHL5 KLHL24 KLHL4	1.30e-03	60	67	3	SM00875
Domain	BACK	KLHL5 KLHL24 KLHL4	1.37e-03	61	67	3	PF07707
Domain	BACK	KLHL5 KLHL24 KLHL4	1.37e-03	61	67	3	IPR011705
Domain	IG_LIKE	PTPRF CD28 UNC5C PTPRU LRRC4 MUSK AMIGO2	1.85e-03	491	67	7	PS50835
Domain	Kelch_1	KLHL5 KLHL24 KLHL4	2.03e-03	70	67	3	PF01344
Domain	Kelch_1	KLHL5 KLHL24 KLHL4	2.03e-03	70	67	3	IPR006652
Domain	Ig-like_dom	PTPRF CD28 UNC5C PTPRU LRRC4 MUSK AMIGO2	2.12e-03	503	67	7	IPR007110
Domain	Tyr_Pase_AS	PTPRF PTPRJ PTPRU	2.29e-03	73	67	3	IPR016130
Domain	-	PTPRF PTPRJ CD28 UNC5C PTPRU LRRC4 MUSK AMIGO2	2.49e-03	663	67	8	2.60.40.10
Domain	RRM_dom_euk	PABPC3 PABPC1	3.06e-03	23	67	2	IPR003954
Domain	RRM_1	PABPC3 PABPC1	3.06e-03	23	67	2	SM00361
Domain	TYR_PHOSPHATASE_1	PTPRF PTPRJ PTPRU	3.65e-03	86	67	3	PS00383
Domain	Ig-like_fold	PTPRF PTPRJ CD28 UNC5C PTPRU LRRC4 MUSK AMIGO2	3.65e-03	706	67	8	IPR013783
Domain	TYR_PHOSPHATASE_2	PTPRF PTPRJ PTPRU	3.77e-03	87	67	3	PS50056
Domain	TYR_PHOSPHATASE_dom	PTPRF PTPRJ PTPRU	3.77e-03	87	67	3	IPR000387
Domain	IG	PTPRF UNC5C PTPRU LRRC4 MUSK AMIGO2	3.96e-03	421	67	6	SM00409
Domain	Ig_sub	PTPRF UNC5C PTPRU LRRC4 MUSK AMIGO2	3.96e-03	421	67	6	IPR003599
Domain	Ig_I-set	PTPRF UNC5C LRRC4 MUSK	4.83e-03	190	67	4	IPR013098
Domain	I-set	PTPRF UNC5C LRRC4 MUSK	4.83e-03	190	67	4	PF07679
Domain	RRM_1	PABPC3 PABPC1 HNRNPH1 HNRNPH2	6.63e-03	208	67	4	PF00076
Pubmed	Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis.	PABPC3 PABPC1 HNRNPH2	8.49e-07	10	68	3	16798735
Pubmed	Defining the membrane proteome of NK cells.	ATAD1 MTOR ANXA6 MARCHF6 CEP41 ELOVL1 PLEKHA5 CHST11 NUF2 PABPC1 HNRNPH1 HNRNPH2	2.50e-06	1168	68	12	19946888
Pubmed	Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells.	PABPC3 PABPC1	3.77e-06	2	68	2	19020299
Pubmed	IDO1 involvement in mTOR pathway: a molecular mechanism of resistance to mTOR targeting in medulloblastoma.	IDO1 MTOR	3.77e-06	2	68	2	27174915
Pubmed	Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis.	PABPC3 PABPC1	3.77e-06	2	68	2	26971890
Pubmed	Levels of free PABP are limited by newly polyadenylated mRNA in early Spisula embryogenesis.	PABPC3 PABPC1	3.77e-06	2	68	2	10954604
Pubmed	The promoter of the Poly(A) binding protein 2 (Pabp2) retroposon is derived from the 5'-untranslated region of the Pabp1 progenitor gene.	PABPC3 PABPC1	3.77e-06	2	68	2	10534404
Pubmed	The mouse gene encoding the testis-specific isoform of Poly(A) binding protein (Pabp2) is an expressed retroposon: intimations that gene expression in spermatogenic cells facilitates the creation of new genes.	PABPC3 PABPC1	3.77e-06	2	68	2	9732454
Pubmed	Nucleotide sequence of a mouse testis poly(A) binding protein cDNA.	PABPC3 PABPC1	3.77e-06	2	68	2	1630930
Pubmed	Developmental expression of poly(A) binding protein mRNAs during spermatogenesis in the mouse.	PABPC3 PABPC1	3.77e-06	2	68	2	7893484
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TNIK STK3 ABLIM1 GGA2 MTOR CSNK2B AAK1 CEP41 PLEKHA5 DHX35 PABPC1	5.14e-06	1038	68	11	26673895
Pubmed	Embryonic Poly(A)-Binding Protein Is Required During Early Stages of Mouse Oocyte Development for Chromatin Organization, Transcriptional Silencing, and Meiotic Competence.	PABPC3 PABPC1	1.13e-05	3	68	2	26134869
Pubmed	Infectious tolerance via the consumption of essential amino acids and mTOR signaling.	IDO1 MTOR	1.13e-05	3	68	2	19567830
Pubmed	Human testis expresses a specific poly(A)-binding protein.	PABPC3 PABPC1	1.13e-05	3	68	2	11328870
Pubmed	Superovulation alters embryonic poly(A)-binding protein (Epab) and poly(A)-binding protein, cytoplasmic 1 (Pabpc1) gene expression in mouse oocytes and early embryos.	PABPC3 PABPC1	1.13e-05	3	68	2	25034140
Pubmed	Epab is dispensable for mouse spermatogenesis and male fertility.	PABPC3 PABPC1	1.13e-05	3	68	2	24599567
Pubmed	Co-Localization of Insulin-Like Growth Factor Binding Protein-1, Casein Kinase-2β, and Mechanistic Target of Rapamycin in Human Hepatocellular Carcinoma Cells as Demonstrated by Dual Immunofluorescence and in Situ Proximity Ligation Assay.	MTOR CSNK2B	1.13e-05	3	68	2	29037858
Pubmed	Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription.	STK3 HNRNPH1	1.13e-05	3	68	2	20145135
Pubmed	Differential 3' Processing of Specific Transcripts Expands Regulatory and Protein Diversity Across Neuronal Cell Types.	PABPC3 PABPC1	1.13e-05	3	68	2	29578408
Pubmed	SIRT1 Functions as a Negative Regulator of Eukaryotic Poly(A)RNA Transport.	PABPC3 PABPC1	1.13e-05	3	68	2	28756945
Pubmed	The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.	PABPC3 PABPC1	1.13e-05	3	68	2	26843391
Pubmed	Domain-functional analyses of PIWIL1 and PABPC1 indicate their synergistic roles in protein translation via 3'-UTRs of meiotic mRNAs.	PABPC3 PABPC1	1.13e-05	3	68	2	29701755
Pubmed	Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.	PABPC3 PABPC1	1.13e-05	3	68	2	21940797
Pubmed	hnRNPs H, H' and F behave differently with respect to posttranslational cleavage and subcellular localization.	HNRNPH1 HNRNPH2	1.13e-05	3	68	2	10456323
Pubmed	Translation repression via modulation of the cytoplasmic poly(A)-binding protein in the inflammatory response.	PABPC3 PABPC1	1.13e-05	3	68	2	28635594
Pubmed	The mouse Y-box protein, MSY2, is associated with a kinase on non-polysomal mouse testicular mRNAs.	PABPC3 PABPC1	1.13e-05	3	68	2	10076007
Pubmed	Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries.	PABPC3 PABPC1	1.13e-05	3	68	2	25370180
Pubmed	Heterogeneous nuclear ribonucleoproteins F and H/H' show differential expression in normal and selected cancer tissues.	HNRNPH1 HNRNPH2	1.13e-05	3	68	2	14980514
Pubmed	The pseudogene PRELID1P6 promotes glioma progression via the hnHNPH1-Akt/mTOR axis.	MTOR HNRNPH1	1.13e-05	3	68	2	34108621
Pubmed	Epab and Pabpc1 are differentially expressed during male germ cell development.	PABPC3 PABPC1	1.13e-05	3	68	2	22814100
Pubmed	Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance.	HNRNPH1 HNRNPH2	1.13e-05	3	68	2	21068389
Pubmed	Cytoplasmic poly(A)-binding protein 1 (PABPC1) interacts with the RNA-binding protein hnRNPLL and thereby regulates immunoglobulin secretion in plasma cells.	PABPC3 PABPC1	1.13e-05	3	68	2	28611064
Pubmed	A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway.	PABPC3 PABPC1	1.13e-05	3	68	2	37665675
Pubmed	De novo variants in the PABP domain of PABPC1 lead to developmental delay.	PABPC3 PABPC1	1.13e-05	3	68	2	35511136
Pubmed	Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes.	HNRNPH1 HNRNPH2	1.13e-05	3	68	2	7499401
Pubmed	Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R.	PABPC3 TLE4 PABPC1	1.40e-05	24	68	3	25157170
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	STK3 ABLIM1 TIMM10B ATAD1 MTOR CSNK2B PLEKHA5 RNF41 PABPC1	1.59e-05	754	68	9	33060197
Pubmed	Regulation of poly(A) binding protein function in translation: Characterization of the Paip2 homolog, Paip2B.	PABPC3 PABPC1	2.25e-05	4	68	2	16804161
Pubmed	Evolution of complexity in the zebrafish synapse proteome.	PABPC3 PABPC1	2.25e-05	4	68	2	28252024
Pubmed	The TSC-mTOR signaling pathway regulates the innate inflammatory response.	MTOR CD28	2.25e-05	4	68	2	18848473
Pubmed	An embryonic poly(A)-binding protein (ePAB) is expressed in mouse oocytes and early preimplantation embryos.	PABPC3 PABPC1	2.25e-05	4	68	2	15630085
Pubmed	Indoleamine 2,3-dioxygenase 1 is essential for sustaining durable antibody responses.	IDO1 CD28	2.25e-05	4	68	2	34788602
Pubmed	Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP.	PABPC3 PABPC1	2.25e-05	4	68	2	18490513
Pubmed	UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant.	PABPC3 PABPC1	2.25e-05	4	68	2	15314026
Pubmed	Stress granules inhibit apoptosis by reducing reactive oxygen species production.	PABPC3 PABPC1	2.25e-05	4	68	2	23230274
Pubmed	Transthyretin Upregulates Long Non-Coding RNA MEG3 by Affecting PABPC1 in Diabetic Retinopathy.	PABPC3 PABPC1	2.25e-05	4	68	2	31847264
Pubmed	RNA-binding proteins in mouse oocytes and embryos: expression of genes encoding Y box, DEAD box RNA helicase, and polyA binding proteins.	PABPC3 PABPC1	2.25e-05	4	68	2	9883581
Pubmed	Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.	PABPC3 PABPC1	2.25e-05	4	68	2	24129315
Pubmed	cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation.	PABPC3 PABPC1	2.25e-05	4	68	2	28910620
Pubmed	ATXN2-CAG42 sequesters PABPC1 into insolubility and induces FBXW8 in cerebellum of old ataxic knock-in mice.	PABPC3 PABPC1	2.25e-05	4	68	2	22956915
Pubmed	Netrin-G1: a novel glycosyl phosphatidylinositol-linked mammalian netrin that is functionally divergent from classical netrins.	UNC5C LRRC4	2.25e-05	4	68	2	10964959
Pubmed	Functional cloning of genes that suppress oxidative stress-induced cell death: TCTP prevents hydrogen peroxide-induced cell death.	PABPC3 PABPC1	2.25e-05	4	68	2	19328788
Pubmed	TERRA transcripts are bound by a complex array of RNA-binding proteins.	PABPC3 PABPC1 HNRNPH2	2.26e-05	28	68	3	20975687
Pubmed	Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis.	PABPC3 NSUN2 PABPC1 HNRNPH1 HNRNPH2	2.26e-05	172	68	5	26336360
Pubmed	A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.	TIMM10B MTOR CSNK2B PLEKHA5 RNF41 PABPC1	2.64e-05	298	68	6	32353859
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	TNIK RASGRP4 BRDT IDO1 MTOR ANXA6 LARS1 CEP41 DHX35 CHST11 NSUN2	2.73e-05	1242	68	11	30973865
Pubmed	Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression.	STK3 PABPC1 HNRNPH1 HNRNPH2	3.01e-05	90	68	4	33087562
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	DIS3L2 PABPC3 RNF41 PABPC1 HNRNPH1 HNRNPH2 RYR2	3.36e-05	462	68	7	31138677
Pubmed	NFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cells.	PABPC3 PABPC1 HNRNPH1	3.40e-05	32	68	3	17267499
Pubmed	HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage.	PABPC3 PABPC1	3.75e-05	5	68	2	19956697
Pubmed	Interaction of HuDA and PABP at 5'UTR of mouse insulin2 regulates insulin biosynthesis.	PABPC3 PABPC1	3.75e-05	5	68	2	29590218
Pubmed	Poly(A) tail length regulates PABPC1 expression to tune translation in the heart.	PABPC3 PABPC1	3.75e-05	5	68	2	28653618
Pubmed	Embryonic Poly(A)-Binding Protein (EPAB) Is Required for Granulosa Cell EGF Signaling and Cumulus Expansion in Female Mice.	PABPC3 PABPC1	3.75e-05	5	68	2	26492470
Pubmed	Isolation of cDNAs from a mouse astroglial cell line by a subtracted cDNA library.	PABPC3 PABPC1	3.75e-05	5	68	2	1701491
Pubmed	AKAP3 synthesis is mediated by RNA binding proteins and PKA signaling during mouse spermiogenesis.	PABPC3 PABPC1	3.75e-05	5	68	2	24648398
Pubmed	MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of GNRH1 mRNA in mammalian puberty.	PABPC3 PABPC1	3.75e-05	5	68	2	33744966
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	RASGRP4 KLHL5 ANXA6 MARCHF6 RNF41 HNRNPH1	4.06e-05	322	68	6	26514267
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	STK3 PHLDB3 PALD1 ABLIM1 ATAD1 MTOR CSNK2B LARS1 AAK1 PLEKHA5 NUF2	4.78e-05	1321	68	11	27173435
Pubmed	Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.	MUSK RYR2	5.62e-05	6	68	2	26025922
Pubmed	Disruption of mouse poly(A) polymerase mGLD-2 does not alter polyadenylation status in oocytes and somatic cells.	PABPC3 PABPC1	5.62e-05	6	68	2	17927953
Pubmed	CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1.	MTOR CD28	5.62e-05	6	68	2	18337562
Pubmed	Translation of insulin granule proteins are regulated by PDI and PABP.	PABPC3 PABPC1	5.62e-05	6	68	2	32248978
Pubmed	The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein.	PABPC3 PABPC1	5.62e-05	6	68	2	10358005
Pubmed	Embryonic poly(A)-binding protein is differently expressed and interacts with the messenger RNAs in the mouse oocytes and early embryos.	PABPC3 PABPC1	5.62e-05	6	68	2	30302808
Pubmed	Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice.	DHX35 CHST11 NSUN2	6.71e-05	40	68	3	27996060
Pubmed	Update on the Kelch-like (KLHL) gene family.	KLHL5 KLHL24 KLHL4	7.23e-05	41	68	3	23676014
Pubmed	E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.	PABPC3 PABPC1	7.86e-05	7	68	2	34143182
Pubmed	Genetic imbalances in preleukemic thymuses.	PABPC3 PABPC1	7.86e-05	7	68	2	11322760
Pubmed	Chromosomal localization of three human poly(A)-binding protein genes and four related pseudogenes.	PABPC3 PABPC1	7.86e-05	7	68	2	10543404
Pubmed	NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome.	PABPC3 PABPC1	7.86e-05	7	68	2	34784943
Pubmed	A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins.	HNRNPH1 HNRNPH2	7.86e-05	7	68	2	31704785
Pubmed	Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.	HNRNPH1 HNRNPH2	7.86e-05	7	68	2	25846207
Pubmed	Transmembrane homodimerization of receptor-like protein tyrosine phosphatases.	PTPRJ PTPRU	7.86e-05	7	68	2	15978577
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	GGA2 RNF44 MARCHF6 LARS1 AAK1 PLEKHA5 ZZEF1	7.87e-05	529	68	7	14621295
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TNIK ZNF462 ABLIM1 DIP2C PLEKHA5	8.11e-05	225	68	5	12168954
Pubmed	Viral immune modulators perturb the human molecular network by common and unique strategies.	PHLDB3 CSNK2B HNRNPH1 HNRNPH2	8.11e-05	116	68	4	22810585
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TNIK PALD1 ABLIM1 CSNK2B LARS1 AAK1 NSUN2 PABPC1 HNRNPH1	8.34e-05	934	68	9	33916271
Pubmed	ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center.	NSUN2 PABPC1 HNRNPH1	1.02e-04	46	68	3	20890123
Pubmed	Near-Infrared Luciferase Complementation Assay with Enhanced Bioluminescence for Studying Protein-Protein Interactions and Drug Evaluation Under Physiological Conditions.	MTOR PABPC1	1.05e-04	8	68	2	36135776
Pubmed	Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse.	PABPC3 PABPC1	1.05e-04	8	68	2	21262862
Pubmed	Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.	PABPC3 PABPC1	1.05e-04	8	68	2	22621333
Pubmed	Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome.	CSNK2B HNRNPH1 HNRNPH2	1.23e-04	49	68	3	27352031
Pubmed	RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis.	PABPC3 PABPC1	1.34e-04	9	68	2	36001654
Pubmed	Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.	KLHL5 RYR2	1.34e-04	9	68	2	23829686
Pubmed	Embryonic poly(A)-binding protein is required at the preantral stage of mouse folliculogenesis for oocyte-somatic communication.	PABPC3 PABPC1	1.34e-04	9	68	2	28203794
Pubmed	Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase.	PABPC3 PABPC1	1.34e-04	9	68	2	24396066
Pubmed	Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells.	PABPC3 PABPC1	1.34e-04	9	68	2	18625844
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	TNIK ABLIM1 CD28 HNRNPH1	1.38e-04	133	68	4	15144186
Pubmed	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	ABLIM1 PTPRU AMIGO2	1.48e-04	52	68	3	22219177
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	ABLIM1 PTPRF CSNK2B ANXA6 LARS1 NSUN2 PABPC1 HNRNPH1 HNRNPH2	1.67e-04	1024	68	9	24711643
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRF PTPRJ PTPRU	2.88e-05	21	52	3	813
GeneFamily	Kelch like\|BTB domain containing	KLHL5 KLHL24 KLHL4	2.38e-04	42	52	3	617
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	PTPRF UNC5C LRRC4 MUSK	1.18e-03	161	52	4	593
GeneFamily	RNA binding motif containing	PABPC3 PABPC1 HNRNPH1 HNRNPH2	3.26e-03	213	52	4	725
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL5 KLHL24 KLHL4	6.75e-03	134	52	3	861
GeneFamily	Ring finger proteins	RNF44 RNF19B MARCHF6 RNF41	8.00e-03	275	52	4	58
GeneFamily	Fibronectin type III domain containing	PTPRF PTPRJ PTPRU	1.09e-02	160	52	3	555
Coexpression	GSE29164_DAY3_VS_DAY7_CD8_TCELL_TREATED_MELANOMA_DN	PTPRJ CSNK2B ANXA6 AAK1 CEP41 CA10	1.14e-05	200	66	6	M8494
Coexpression	GSE7852_THYMUS_VS_FAT_TCONV_UP	ABLIM1 CACNA2D4 GGA2 PTPRF DIP2C AMIGO2	1.14e-05	200	66	6	M5749
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	TNIK ABLIM1 KLHL24 AAK1 PLEKHA5 RYR2	4.61e-07	190	68	6	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	moderate-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CD28 TLE4 AAK1 CA10 PABPC1 HNRNPH1	5.54e-07	196	68	6	9152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ABLIM1 BCO2 AAK1 PLEKHA5 RYR2	9.41e-06	185	68	5	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	ABLIM1 KLHL24 AAK1 PLEKHA5 RYR2	1.10e-05	191	68	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	TNIK KLHL24 BCO2 AAK1 RYR2	1.13e-05	192	68	5	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TNIK ABLIM1 PTPRJ DIP2C PLEKHA5	1.18e-05	194	68	5	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	PBMC-Control-Lymphocyte-T/NK\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TNIK ABLIM1 CD28 ANXA6 AAK1	1.37e-05	200	68	5	1dd0141e87902d96a76edcd966988f61a532c808
ToppCell	PBMC-Control-Lymphocyte-T/NK\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	TNIK ABLIM1 CD28 ANXA6 AAK1	1.37e-05	200	68	5	7f79ab7737188b1f7fb5c2a0b1d6d2a565d36385
ToppCell	Control-Lymphoid_T/NK\|Control / Disease group, lineage and cell class	TNIK ABLIM1 CD28 ANXA6 AAK1	1.37e-05	200	68	5	b5d5eead192a22c6b5ea699fe36873809fe6e3e2
ToppCell	Control-Control-Lymphocyte-T/NK\|Control / Disease, condition lineage and cell class	TNIK ABLIM1 CD28 ANXA6 AAK1	1.37e-05	200	68	5	6a399d9fa005547e5fadd3c0dafd7e4381732460
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA3 PTPRF IDO1 ARMC12	6.44e-05	141	68	4	3fa3d2a8ebd9c285168ecea6db9cad74d3a3e85a
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA3 PTPRF IDO1 ARMC12	6.44e-05	141	68	4	cabb5b8c0874813c713508af2ac620ab0d61ab6f
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-7\|TCGA-Bladder / Sample_Type by Project: Shred V9	PALD1 RASGRP4 CACNA2D4 KLHL4	8.19e-05	150	68	4	3ab17045b2c43bb4f0ebba6aa0cfb22e076a24f9
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-3\|TCGA-Thryoid / Sample_Type by Project: Shred V9	TLE4 AOX1 RYR2 KLHL4	9.07e-05	154	68	4	4e9203c220a44c70cd7979796a0b461991422257
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue\|TCGA-Thryoid / Sample_Type by Project: Shred V9	TLE4 AOX1 RYR2 KLHL4	1.00e-04	158	68	4	8e48952af0831a1fc71ad422e8216b5a92a75991
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue\|TCGA-Thryoid / Sample_Type by Project: Shred V9	TLE4 AOX1 RYR2 KLHL4	1.00e-04	158	68	4	e5b55c15a8c99c8d7fc94949f0d3c22e0c3fee7b
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal\|TCGA-Thryoid / Sample_Type by Project: Shred V9	TLE4 AOX1 RYR2 KLHL4	1.00e-04	158	68	4	55214d674808584e4d48f8c5e3b8c0e206cb9bb8
ToppCell	facs-Liver-Non-hepatocytes-24m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 CD28 ANXA6 NUF2	1.10e-04	162	68	4	15d5d31a75e26bcd41919a00300c68e9f00f0002
ToppCell	normal-na-Lymphocytic_T-T4_reg-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	TNIK CD28 AAK1 KLHL4	1.13e-04	163	68	4	43887e7687fc6367efac0c1f56a9534b06f47b7f
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-9\|TCGA-Brain / Sample_Type by Project: Shred V9	TNIK ABLIM1 KLHL5 PLEKHA5	1.24e-04	167	68	4	013971700e80b71e4b8c79b8fff0d8beeac295c3
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Regulatory_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK PHLDB3 CD28 ANXA6	1.27e-04	168	68	4	1df3c8c7a6dceb901805eaba7f86f9943f4f1a9d
ToppCell	droplet-Lung-nan-3m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK PHLDB3 CD28 ANXA6	1.27e-04	168	68	4	1586451d437b70b2dffe41d782b694702dcaf50b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK BCO2 BRDT CD28	1.33e-04	170	68	4	adb625124832b0786a590e8f75b61e7263a1e0d4
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK3 BCO2 AAK1 DIP2C	1.36e-04	171	68	4	d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCell	droplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHLDB3 RASGRP4 IDO1 AAK1	1.36e-04	171	68	4	e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 RASGRP4 TEX53 CHST11	1.39e-04	172	68	4	f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF462 IDO1 ANXA6 PLEKHA5	1.45e-04	174	68	4	991f7eab69ea3ee1045a4e44ce60a96db13df6d1
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZNF462 IDO1 ANXA6 PLEKHA5	1.45e-04	174	68	4	c8cec89369cf3896c5626e447051e76a142cb6df
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABLIM1 CACNA2D4 CD28 PABPC1	1.52e-04	176	68	4	8960b3b9aca11f6edf990dd35a01bb289c176523
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABLIM1 CD28 AAK1 HNRNPH1	1.55e-04	177	68	4	64b8f665fdaf975558af2ad7d9b54d206de8350c
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABLIM1 CACNA2D4 CD28 PABPC1	1.55e-04	177	68	4	5b8fdf88c3a99c827dd1934beb5be102c411025a
ToppCell	367C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PTPRF IDO1 ANXA6 PTPRU	1.55e-04	177	68	4	a0ff337f11bdb11959ac71805ff94be6b4ec1083
ToppCell	LPS-antiTNF-Myeloid-Neutrophils-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRJ IDO1 RNF19B CHST11	1.58e-04	178	68	4	afcc92e8fe313c85eaf617cf4dbc3058da6c99d6
ToppCell	droplet-Marrow-nan-3m-Hematologic-hematopoietic_precursor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK ABLIM1 CD28 PLEKHA5	1.58e-04	178	68	4	8aef208b6351143562c87715bb11628880abce94
ToppCell	LPS-antiTNF-Myeloid-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRJ IDO1 RNF19B CHST11	1.58e-04	178	68	4	bd689205bc92cda5f71df64c2332ff76adcd84b4
ToppCell	normal-na-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ABLIM1 CD28 AAK1 PABPC1	1.58e-04	178	68	4	fa3585383a1e7da460c88a802aaa81246d681b6b
ToppCell	Mild-Lymphoid-T-innate_T\|Mild / Condition, Lineage, Cell class and cell subclass	ABLIM1 CD28 ANXA6 CA10	1.62e-04	179	68	4	abc0fbe101a464a2c85755a974a3d5c2b968fe46
ToppCell	BAL-Control-Lymphocyte-T/NK-CD8+_T-MAIT-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABLIM1 CD28 ANXA6 CA10	1.65e-04	180	68	4	163c34783f013b3904ae2d43b7edde4d55a3e2e5
ToppCell	BAL-Control-Lymphocyte-T/NK-CD8+_T-MAIT\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABLIM1 CD28 ANXA6 CA10	1.65e-04	180	68	4	12cd0b1c8cdf4b11f057657e2196c20ed54d222a
ToppCell	COVID-19-T_cells-Tregs\|COVID-19 / group, cell type (main and fine annotations)	TNIK PTPRJ CD28 CHST11	1.69e-04	181	68	4	534659cf754326c6a73c0daa30e9d610612a0292
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABLIM1 CACNA2D4 CD28 PABPC1	1.69e-04	181	68	4	6a32eb83aa39484ca43c91e6b58302d8dea84b7e
ToppCell	wk_20-22-Hematologic-Meg-ery-Platelet\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TNIK KLHL5 KLHL24 AMIGO2	1.69e-04	181	68	4	724efbc200e8388829bc7d81830c2689a95fa838
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Neutrophils\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRJ IDO1 RNF19B CHST11	1.72e-04	182	68	4	243c783675df495ea4112dbf710712c44ea6b4f1
ToppCell	CTRL-Myeloid-cDC\|Myeloid / Disease state, Lineage and Cell class	PALD1 IDO1 ANXA6 PLEKHA5	1.72e-04	182	68	4	ee137574b8f0e684a4a7cb26226877c471cae433
ToppCell	IIH-Treg-proli_CD4\|IIH / Condition, Cell_class and T cell subcluster	KLHL5 DIS3L2 MTOR ABHD11	1.72e-04	182	68	4	5c7d02da9ca2bca49db9832704b6894dfaa08a71
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK ABLIM1 CD28 PLEKHA5	1.72e-04	182	68	4	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK ABLIM1 CD28 PLEKHA5	1.72e-04	182	68	4	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Neutrophils-Neutrophils\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRJ IDO1 RNF19B CHST11	1.72e-04	182	68	4	18790a394dc32b3cef99cdbf826392c520e38b4a
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK ABLIM1 CD28 ANXA6	1.76e-04	183	68	4	317b756378a9efd8ecb754acf7273f83f996e106
ToppCell	CTRL-Myeloid-cDC\|CTRL / Disease state, Lineage and Cell class	PALD1 IDO1 ANXA6 PLEKHA5	1.76e-04	183	68	4	20c4d16de7e090df3556a4458f783383a26871b6
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK ABLIM1 CD28 AAK1	1.76e-04	183	68	4	f2ef110bf29b1a8276ef216238363e542db262c1
ToppCell	normal-na-Lymphocytic_T-T8_naive-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ABLIM1 AAK1 CEP41 PABPC1	1.80e-04	184	68	4	4a81190b36d197736663e6177d3b76c1cb6282d6
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_2\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PALD1 KLHL5 IDO1 PLEKHA5	1.80e-04	184	68	4	0a26bcc6610f756939e32a4d6dfeebcbf3a1db86
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	ABLIM1 AAK1 PLEKHA5 RYR2	1.80e-04	184	68	4	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK ABLIM1 CD28 AAK1	1.80e-04	184	68	4	5350b58aa9979631228835d11eb45ddf81d08bff
ToppCell	droplet-Thymus\|droplet / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 PTPRF BRDT CD28	1.83e-04	185	68	4	83a78d17ad59503a694c1250082c4d8ae74d63e1
ToppCell	Control-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	PHLDB3 PALD1 IDO1 PLEKHA5	1.87e-04	186	68	4	3de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TNIK ZNF462 DIP2C PLEKHA5	1.91e-04	187	68	4	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	LPS-IL1RA+antiTNF-Myeloid\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRJ IDO1 RNF19B CHST11	1.91e-04	187	68	4	4e0bbef6ba0d1b3e1f8d900d4a9dbd41f09a7bc5
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	TNIK KLHL24 BCO2 AAK1	1.95e-04	188	68	4	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-double_negative_T_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK RASGRP4 CD28 KLHL4	1.95e-04	188	68	4	e0184d9f6687d7ecb8fc461294ff7208f49c437c
ToppCell	CF-Lymphoid-T_cell_&_NK_cell\|Lymphoid / Disease state, Lineage and Cell class	TNIK PTPRJ CD28 AAK1	1.95e-04	188	68	4	15057036b46c9df621ec4955aa94ca3036245d45
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK ABLIM1 CD28 AAK1	1.99e-04	189	68	4	9ab77c6fcb573854da5922412f53d2168bda6b58
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	ABLIM1 KLHL24 PLEKHA5 RYR2	1.99e-04	189	68	4	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK ABLIM1 CD28 AAK1	1.99e-04	189	68	4	5a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TNIK PTPRJ CD28 AAK1	2.03e-04	190	68	4	b69709323a9f1b368b5a4f87295b9f7fd9c9be8e
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_em\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZNF462 CD28 ANXA6 AAK1	2.03e-04	190	68	4	1634a6044dce4e026a63976031a498c7460e3dce
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	UNC5C AOX1 MUSK RYR2	2.03e-04	190	68	4	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	ABLIM1 KLHL24 PLEKHA5 RYR2	2.03e-04	190	68	4	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_em-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZNF462 CD28 ANXA6 AAK1	2.03e-04	190	68	4	08813c2f9321b82f0ec66854bb7a383aa1171780
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK ABLIM1 CD28 AAK1	2.07e-04	191	68	4	9bb6a6b88f351217455765ba07a6acf11fda98f4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TNIK ABLIM1 AOX1 PLEKHA5	2.07e-04	191	68	4	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TNIK ABLIM1 AOX1 PLEKHA5	2.07e-04	191	68	4	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK ABLIM1 CD28 AAK1	2.07e-04	191	68	4	d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCell	LV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	STK3 UNC5C PLEKHA5 MUSK	2.07e-04	191	68	4	d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	STK3 UNC5C AOX1 MUSK	2.07e-04	191	68	4	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	control-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TNIK ZNF462 TIMM10B APOBEC3F	2.07e-04	191	68	4	afebdc59a1f884ce3f2f5fe040e16b0e95e4e7c5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK ABLIM1 CD28 AAK1	2.07e-04	191	68	4	696921a4f160b6b55698652488ed781e855e5e51
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	UNC5C AOX1 MUSK RYR2	2.07e-04	191	68	4	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	NS-critical-d_07-13-Lymphoid-Treg\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TNIK CD28 ANXA6 AAK1	2.11e-04	192	68	4	cd34defac6565d34db507918e791b09c79f7d1f8
ToppCell	NS-moderate-d_16-33-Lymphoid-Treg\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CD28 ANXA6 AAK1 CA10	2.11e-04	192	68	4	48d557071bad80edd3ec6e5ad8dcd97037da9553
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK ABLIM1 CD28 AAK1	2.11e-04	192	68	4	1c0ce299cee9ab5cdea256f3e8c1e5598577a8b6
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	TNIK ABLIM1 AAK1 HNRNPH1	2.11e-04	192	68	4	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	UNC5C AOX1 MUSK RYR2	2.11e-04	192	68	4	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK ABLIM1 CD28 HNRNPH1	2.11e-04	192	68	4	348d39da3016dc6dbfa65d108e5def35aa7f19dd
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	STK3 PTPRJ DIP2C PLEKHA5	2.11e-04	192	68	4	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL5 AAK1 PTPRU MUSK	2.16e-04	193	68	4	c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	TNIK ABLIM1 BCO2 RYR2	2.16e-04	193	68	4	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABLIM1 CD28 PABPC1 HNRNPH1	2.16e-04	193	68	4	4e78ddc96d8e403a21c4a303b1f26512d2ac91e8
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	UNC5C AOX1 MUSK RYR2	2.16e-04	193	68	4	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	UNC5C DIP2C PLEKHA5 RYR2	2.16e-04	193	68	4	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABLIM1 PTPRJ DIP2C PLEKHA5	2.16e-04	193	68	4	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	UNC5C AOX1 MUSK RYR2	2.20e-04	194	68	4	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	T/NK_cells-CD4+_Naive_T_cell\|World / Lineage and Cell class	ABLIM1 CD28 AAK1 PABPC1	2.20e-04	194	68	4	4c6cdedf35c5416a52cb931637715b23d5d07996
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	STK3 UNC5C AOX1 PLEKHA5	2.20e-04	194	68	4	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK ABLIM1 CD28 AAK1	2.20e-04	194	68	4	a44be2f021cfdd0fcdc698c3f04d66db7a1aa6c2
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TNIK CD28 AAK1 PABPC1	2.24e-04	195	68	4	e4caa01d2040a6f4dd90e68c2e1e99c5405e2eba
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TNIK ABLIM1 CD28 HNRNPH1	2.24e-04	195	68	4	4bdedd924564a260841a9153604026b57487c83d
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABLIM1 CD28 ANXA6 PABPC1	2.24e-04	195	68	4	068210aa57e733cbcb54a0b20616f0cb2a1ff639
ToppCell	Healthy_Control-Myeloid-mDC\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	PALD1 KLHL5 BCO2 IDO1	2.24e-04	195	68	4	32f505b2c24f4386367706b775e79271f99156f2
Disease	Pena-Shokeir syndrome type I	SLC18A3 MUSK	1.37e-04	8	66	2	C1276035
Disease	salicylurate measurement	ABLIM1 RYR2	3.78e-04	13	66	2	EFO_0010532
Disease	acute lymphoblastic leukemia	KLHL5 PTPRJ RYR2	4.42e-04	66	66	3	EFO_0000220
Disease	phosphatidylcholine 36:3 measurement	PABPC1 MUSK	5.08e-04	15	66	2	EFO_0010381
Disease	carotid plaque build	BRDT PTPRU MUSK	8.95e-04	84	66	3	EFO_0006501
Disease	Autism Spectrum Disorders	CEP41 NSUN2 RYR2	9.26e-04	85	66	3	C1510586
Disease	Myasthenic Syndromes, Congenital	SLC18A3 MUSK	1.32e-03	24	66	2	C0751882
Disease	unipolar depression, response to selective serotonin reuptake inhibitor	CYP2D6 CHST11	1.32e-03	24	66	2	EFO_0003761, EFO_0005658
Disease	diacylglycerol 34:2 measurement	CACNA2D4 MUSK	1.43e-03	25	66	2	EFO_0010353
Disease	hypertension, COVID-19	ULK3 PTPRJ	1.67e-03	27	66	2	EFO_0000537, MONDO_0100096
Disease	Adult T-Cell Lymphoma/Leukemia	CD28 CSNK2B	2.20e-03	31	66	2	C0023493
Disease	triacylglycerol 54:3 measurement	CACNA2D4 MUSK	2.20e-03	31	66	2	EFO_0010421

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLHSDYMNMTPRRPG	CD28	186	P10747
RDYQTLPDGHMPAMR	ABLIM1	686	O14639
MHCLIRYMLEPDPDK	AAK1	286	Q2M2I8
YNPPDHEVVTMARML	BRDT	351	Q58F21
HPEIMRLFPRAQMQT	ABHD11	276	Q8NFV4
MSLRRHIGNPEYLMK	CEP41	1	Q9BYV8
MLVMYARLRGIPERH	ABCA3	1476	Q99758
YNRIPSMPMHHINLV	AMIGO2	201	Q86SJ2
MSHPDYRMNLRPLGT	DIS3L2	1	Q8IYB7
LPVMVHRLPVFKRYM	BCO2	21	Q9BYV7
DYVHPQLRRVMPALM	ARMC12	181	Q5T9G4
ARLILGLMMPPAHYD	ANXA6	426	P08133
MVMSIYTLLRNHPEP	AOX1	121	Q06278
MDVANFRRVPRMPIY	PALD1	501	Q9ULE6
MLGERLFPLIQAMHP	PABPC1	561	P11940
PKNERLHYLRMMGLE	NSUN2	691	Q08J23
RLFYMVAPSPEAMRI	PHLDB3	611	Q6NSJ2
FLQDMRRYMPPAHRN	IDO1	291	P14902
VYDLRMHRPLMVQTE	PTPRJ	1271	Q12913
IEARLHMPMYLLLGQ	OR2AG2	51	A6NM03
HPMRYEVRMTLGLVA	GPR61	146	Q9BZJ8
VRTHYDPPRKLMAMQ	HNRNPH2	191	P55795
ICKPLHYMVIMNPRL	OR2W3	126	Q7Z3T1
KPEVLHMIYMRALQI	NUF2	41	Q9BZD4
RYWLMRHPEVMHQDP	RASGRP4	126	Q8TDF6
APMHMRGRYLVEVDQ	LRRC4	331	Q9HBW1
MQNLVHRRIYPFLLM	MARCHF6	841	O60337
HRRIYPFLLMVVVLM	MARCHF6	846	O60337
HVKVLQEMLSMYRRP	GGA2	241	Q9UJY4
VRTHYDPPRKLMAMQ	HNRNPH1	191	P31943
AMKYHLLPERRPMLQ	KLHL5	441	Q96PQ7
YHLLPERRSMMQSPR	KLHL4	406	Q9C0H6
MLGERLFPLIQAMHP	PABPC3	556	Q9H361
PMPAYDRHRVKLHPM	PTPRU	921	Q92729
EILRNPMEAMYPHIF	APOBEC3F	186	Q8IUX4
YHILGNEMMSPRTRP	KLHL24	291	Q6TFL4
VMEYLHVLSRPMVIN	CACNA2D4	466	Q7Z3S7
QVRRPEMGDQAHMPY	CYP2D6	341	P10635
MKRHLRVLPMYAGLP	DHX35	306	Q9H5Z1
AMELRGMRYHPIDIE	DIP2C	1446	Q9Y2E4
VMKHADPRIQGYPLM	ELOVL1	11	Q9BW60
MLFMVHPEYRPKRPA	CSNK2B	166	P67870
EYRHRKMKPVQMVPA	GPR173	211	Q9NS66
PVYITRMQMHSLRLL	CA10	256	Q9NS85
TVAHLRPVPRIMRNM	RNF41	61	Q9H4P4
IRYTQMPHVMEVILP	RYR2	3226	Q92736
MRRLNYQTPGMRDHP	PTPRF	1316	P10586
YMRPVVTHPIDKAMA	OR4C6	256	Q8NH72
LNIEHRIMLRMAPDY	MTOR	2261	P42345
HRLMAAYVQLMPALV	TIMM10B	61	Q9Y5J6
MVIVPIVPDYIAHMR	SLC18A3	51	Q16572
DPPLMHKYEEFMLRR	RNF19B	181	Q6ZMZ0
AENPVTPMLRHLMYK	NDUFAF7	36	Q7L592
THDLRLRLKNYMMPA	LARS1	906	Q9P2J5
HPRLPYDNRMMLKAC	TEX53	51	A0A1B0GU33
AIMRRMPTRFHINQP	ATAD1	246	Q8NBU5
MLHPVMRRNPFGVDI	CHST11	36	Q9NPF2
SMPRLPEHCIEYVRM	UBA3	241	Q8TBC4
YADIHPMRAIFMIPT	STK3	221	Q13188
MHPMRALFLIPRNPA	TNIK	236	Q9UKE5
MIRDLSKMYPQTRHP	TLE4	1	Q04727
GVPYSHMMPRRLSTQ	RNF44	266	Q7L0R7
HRNRLSSAVMPYPML	ZZEF1	191	O43149
NVRSLMPHYQRMHPT	ZNF462	936	Q96JM2
PHNRDINIFRARMMP	ZNF782	121	Q6ZMW2
RNMPSHRAQIMARYP	PLEKHA5	441	Q9HAU0
EMYVTVHRKETMRPP	UNC5C	566	O95185
HVLRGSPLYMAPEMV	ULK3	171	Q6PHR2
DRLHPNPMYQRMPLL	MUSK	546	O15146