Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

1.11e-052672GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

1.11e-052672GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

3.32e-053672GO:0043993
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

PPARGC1A CREBBP EP300

4.60e-0521673GO:0042975
GeneOntologyBiologicalProcessbody morphogenesis

IFT122 SSBP3 CREBBP EP300

6.26e-0564694GO:0010171
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

6.59e-054692GO:0018076
GeneOntologyBiologicalProcessorganelle assembly

PLK2 ARHGEF9 CEP83 DNAH2 RNF213 GPSM2 IFT122 LRBA TMEM231 NEB EP300 WDPCP ZMYND12

8.83e-0511386913GO:0070925
GeneOntologyBiologicalProcessGolgi to plasma membrane transport

VPS35L OSBPL5 PREPL RAB26

8.90e-0570694GO:0006893
GeneOntologyBiologicalProcessembryonic digit morphogenesis

IFT122 TMEM231 CREBBP WDPCP

1.11e-0474694GO:0042733
HumanPhenoWidened distal phalanges

FLNB CREBBP EP300

1.18e-064353HP:0006200
HumanPhenoLarge foramen magnum

GPSM2 CREBBP EP300

5.86e-066353HP:0002700
HumanPhenoAbnormal foramen magnum morphology

FLNB GPSM2 CREBBP EP300

1.51e-0523354HP:0002699
HumanPhenoBroad distal phalanx of finger

FLNB IFT122 CREBBP EP300

2.93e-0527354HP:0009836
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

4.59e-052352HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

4.59e-052352HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

4.59e-052352HP:0001042
HumanPhenoAbnormality of the distal phalanx of the thumb

FLNB CREBBP CWF19L1 EP300

9.41e-0536354HP:0009617
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

1.37e-043352HP:0008752
HumanPhenoPoorly ossified vertebrae

FLNB VPS35L

1.37e-043352HP:0100856
HumanPhenoPhobia

CREBBP EP300

1.37e-043352HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

1.37e-043352HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

1.37e-043352HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

1.37e-043352HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

1.37e-043352HP:0005895
HumanPhenoAbnormal hallux phalanx morphology

VPS35L IFT122 CREBBP EP300

2.48e-0446354HP:0010057
HumanPhenoTrichiasis

CREBBP EP300

2.73e-044352HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

2.73e-044352HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

2.73e-044352HP:0011087
HumanPhenoVascular ring

CREBBP EP300

2.73e-044352HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

2.73e-044352HP:0031207
HumanPhenoAbnormal proximal phalanx morphology of the hand

FLNB VPS35L CREBBP EP300

4.00e-0452354HP:0009834
HumanPhenoShort first metatarsal

VPS35L EP300

4.53e-045352HP:0010105
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

4.53e-045352HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

4.53e-045352HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

4.53e-045352HP:0030421
HumanPhenoAbnormal cheek morphology

TMEM260 FLNB VPS35L IFT122 SIM1 TMEM231 CREBBP EP300

5.06e-04282358HP:0004426
MousePhenoanisocytosis

JAK2 PRKAG1 TF EP300

2.78e-0544564MP:0002642
Domain-

TTC29 VPS41 CSTF3 GPSM2 PSMD3 TTC13 IFT122 TTC9 ZMYND12

5.94e-082076891.25.40.10
DomainTPR-like_helical_dom

TTC29 VPS41 CSTF3 GPSM2 PSMD3 TTC13 IFT122 TTC9 ZMYND12

1.63e-07233689IPR011990
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

1.31e-052682IPR014744
DomainHAT_KAT11

CREBBP EP300

1.31e-052682PF08214
DomainKIX

CREBBP EP300

1.31e-052682PS50952
DomainZnF_TAZ

CREBBP EP300

1.31e-052682SM00551
DomainCBP_P300_HAT

CREBBP EP300

1.31e-052682IPR031162
DomainDUF902

CREBBP EP300

1.31e-052682PF06001
Domain-

CREBBP EP300

1.31e-0526821.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

1.31e-052682IPR010303
Domain-

CREBBP EP300

1.31e-0526821.10.1630.10
DomainCreb_binding

CREBBP EP300

1.31e-052682PF09030
Domain-

CREBBP EP300

1.31e-0526821.10.246.20
Domainzf-TAZ

CREBBP EP300

1.31e-052682PF02135
DomainZF_TAZ

CREBBP EP300

1.31e-052682PS50134
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

1.31e-052682IPR013178
DomainKAT11

CREBBP EP300

1.31e-052682SM01250
DomainZnf_TAZ

CREBBP EP300

1.31e-052682IPR000197
DomainKIX_dom

CREBBP EP300

1.31e-052682IPR003101
DomainKIX

CREBBP EP300

1.31e-052682PF02172
DomainCBP_P300_HAT

CREBBP EP300

1.31e-052682PS51727
DomainTPR_REGION

TTC29 DNAH2 GPSM2 TTC13 TTC9 ZMYND12

3.02e-05165686PS50293
DomainTPR

TTC29 DNAH2 GPSM2 TTC13 TTC9 ZMYND12

3.02e-05165686PS50005
DomainNuc_rcpt_coact

CREBBP EP300

1.94e-046682IPR009110
DomainTPR-contain_dom

TTC29 GPSM2 TTC13 TTC9 ZMYND12

2.17e-04150685IPR013026
DomainPeptidase_M28

FOLH1 ERMP1

8.42e-0412682IPR007484
DomainPeptidase_M28

FOLH1 ERMP1

8.42e-0412682PF04389
DomainPH_dom-like

JAK2 FRMD6 BTK ARHGEF9 OSBPL5 DOCK10 LRBA

8.94e-04426687IPR011993
DomainTPR

TTC29 GPSM2 TTC13 TTC9

1.26e-03129684SM00028
DomainTPR_repeat

TTC29 GPSM2 TTC13 TTC9

1.41e-03133684IPR019734
DomainZZ

CREBBP EP300

1.92e-0318682PF00569
DomainZF_ZZ_2

CREBBP EP300

1.92e-0318682PS50135
DomainZF_ZZ_1

CREBBP EP300

1.92e-0318682PS01357
DomainZnf_ZZ

CREBBP EP300

2.15e-0319682IPR000433
DomainZnF_ZZ

CREBBP EP300

2.15e-0319682SM00291
DomainBromodomain_CS

CREBBP EP300

4.01e-0326682IPR018359
DomainTPR_1

GPSM2 TTC13 TTC9

4.33e-0390683PF00515
DomainTPR_1

GPSM2 TTC13 TTC9

4.33e-0390683IPR001440
Domain-

VPS41 IFT122 LRBA WDPCP PLXNA1

7.29e-033336852.130.10.10
DomainWD40/YVTN_repeat-like_dom

VPS41 IFT122 LRBA WDPCP PLXNA1

7.47e-03335685IPR015943
DomainBROMODOMAIN_1

CREBBP EP300

8.01e-0337682PS00633
DomainBromodomain

CREBBP EP300

8.44e-0338682PF00439
PathwayBIOCARTA_PPARG_PATHWAY

PPARGC1A CREBBP EP300

1.74e-067533MM1573
PathwayBIOCARTA_PPARG_PATHWAY

PPARGC1A CREBBP EP300

2.77e-068533M22058
PathwayREACTOME_HEME_SIGNALING

PPARGC1A CHD9 CREBBP EP300

3.33e-0549534M41832
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CHD9 CREBBP EP300

3.93e-0518533M26942
PathwayBIOCARTA_CARM_ER_PATHWAY

PPARGC1A CREBBP EP300

1.23e-0426533M2499
PathwayPID_HDAC_CLASSIII_PATHWAY

PPARGC1A CREBBP EP300

1.23e-0426533M32
PathwayREACTOME_CIRCADIAN_CLOCK

PPARGC1A CHD9 CREBBP EP300

1.36e-0470534M938
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

1.38e-045532MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

1.38e-045532M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

1.38e-045532M48023
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

1.38e-045532M27228
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

2.06e-046532M22062
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

PPARGC1A CHD9 CREBBP EP300

2.75e-0484534M1008
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

3.83e-048532M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

3.83e-048532M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

3.83e-048532M46443
PathwayPID_IFNG_PATHWAY

JAK2 CREBBP EP300

4.49e-0440533M161
PathwayREACTOME_MITOCHONDRIAL_BIOGENESIS

PPARGC1A PRKAG1 CHD9 CREBBP

4.58e-0496534M26973
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

BTK ITPR3

4.91e-049532M47852
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

4.91e-049532M47451
PathwayWP_IL6_SIGNALING_PATHWAY

JAK2 BTK CREBBP EP300

5.35e-04100534MM15826
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

PPARGC1A CREBBP EP300

5.96e-0444533M27295
PathwayWP_GENES_RELATED_TO_PRIMARY_CILIUM_DEVELOPMENT_BASED_ON_CRISPR

CEP83 IFT122 TMEM231 WDPCP

5.98e-04103534M39826
PathwayREACTOME_ACTIVATION_OF_PPARGC1A_PGC_1ALPHA_BY_PHOSPHORYLATION

PPARGC1A PRKAG1

6.12e-0410532M27146
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

6.12e-0410532M27945
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

7.46e-0411532MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

7.46e-0411532M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

7.46e-0411532M26924
PathwayREACTOME_ADIPOGENESIS

PPARGC1A CHD9 CREBBP EP300

7.66e-04110534M48259
PathwayWP_ENERGY_METABOLISM

PPARGC1A PRKAG1 EP300

7.70e-0448533M39590
PathwayPID_HES_HEY_PATHWAY

JAK2 CREBBP EP300

7.70e-0448533M288
PathwayREACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE

PPARGC1A CEP83 PRKAG1 CHD9 IFT122 CREBBP

8.31e-04297536M27050
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

8.94e-0412532M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

8.94e-0412532M27765
PathwayBIOCARTA_PPARA_PATHWAY

PPARGC1A CREBBP EP300

9.74e-0452533M2404
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

PPARGC1A CHD9 CREBBP EP300

9.96e-04118534M27316
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS

PPARGC1A CHD9 CREBBP

1.15e-0355533M27145
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

1.23e-0314532M27808
PathwayWP_EBOLA_VIRUS_INFECTION_IN_HOST

FLNB VPS41 CREBBP EP300

1.39e-03129534M39693
PathwayWP_KIT_RECEPTOR_SIGNALING

JAK2 BTK EP300

1.41e-0359533M39350
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.41e-0315532MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.41e-0315532M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.41e-0315532MM1439
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

1.41e-0315532M953
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP EP300

1.61e-0316532M27121
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.61e-0316532M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.61e-0316532MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.61e-0316532M8516
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

1.61e-0316532M27940
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

1.82e-0317532MM1509
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

1.82e-0317532M48025
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

CREBBP EP300 FGF16

1.86e-0365533M39682
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

PSMD3 CREBBP EP300 ITPR3

1.87e-03140534M27484
PathwayPID_HIF1_TFPATHWAY

TF CREBBP EP300

1.94e-0366533M255
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION

PPARGC1A CREBBP EP300

1.94e-0366533M27938
PathwayKEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY

JAK2 PPARGC1A PRKAG1

2.03e-0367533M10462
PathwayWP_PATHOPHYSIOLOGICAL_ROLES_OF_DUX4_IN_FSHD1

PPARGC1A EP300

2.04e-0318532M48069
PathwayWP_UROTENSINIIMEDIATED_SIGNALING

JAK2 CREBBP EP300

2.21e-0369533M48052
PathwayREACTOME_FORMATION_OF_PARAXIAL_MESODERM

PSMD3 CREBBP EP300

2.21e-0369533M46439
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

2.28e-0319532M18933
PathwayREACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES

CREBBP EP300

2.28e-0319532M46442
PathwayKEGG_LONG_TERM_POTENTIATION

CREBBP EP300 ITPR3

2.30e-0370533M3115
PathwayWP_KIT_RECEPTOR_SIGNALING_PATHWAY

JAK2 BTK EP300

2.39e-0371533MM15947
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

2.52e-0320532M27881
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300

2.78e-0321532M39593
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

CREBBP EP300

2.78e-0321532M27485
PathwayREACTOME_CELLULAR_RESPONSE_TO_HYPOXIA

PSMD3 CREBBP EP300

2.80e-0375533M641
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

JAK2 FLNB FOLH1 VPS35L ARHGEF9 OSBPL5 VPS41 PRKAG1 CSTF3 RNF213 CHD9 CPD IFT122 LRBA SSBP3 CREBBP RSU1 EP300

4.55e-101489691828611215
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NDST1 FLNB PLK2 SLF2 FOLH1 VPS35L NUCB1 NAP1L1 GPSM2 CHD9 IFT122 LRBA TF CREBBP PREPL EP300

3.32e-091285691635914814
Pubmed

Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro.

NAP1L1 CREBBP EP300

2.99e-08469311940655
Pubmed

Natural helix 9 mutants of PPARγ differently affect its transcriptional activity.

PPARGC1A CREBBP EP300

8.88e-071069330595551
Pubmed

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.

PPARGC1A CREBBP EP300

1.22e-061169315681609
Pubmed

Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.

PPARGC1A CREBBP EP300

1.62e-061269312189208
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

RASSF2 VPS35 MRPS27 PRKAG1 NEB CREBBP RSU1 EP300

2.29e-0643269823455922
Pubmed

Defining the membrane proteome of NK cells.

NUCB1 OSBPL5 NAP1L1 DOCK10 PRKAG1 RNF213 PSMD3 CPD IFT122 ERMP1 LRBA ITPR3

2.93e-061168691219946888
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

FLNB SPTLC2 VPS35 MRPS27 PSMD3 CPD TTC13 TIPRL TF PREPL ITPR3

3.25e-06974691128675297
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

3.88e-06269227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

3.88e-06269234845315
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

3.88e-06269219729597
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

3.88e-06269215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

3.88e-06269229460469
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

3.88e-06269224551300
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

3.88e-06269233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

3.88e-0626929018065
Pubmed

Activation of RASSF2A by p300 induces late apoptosis through histone hyperacetylation.

RASSF2 EP300

3.88e-06269220716062
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

3.88e-06269224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

3.88e-06269230135524
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

3.88e-06269239287984
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

3.88e-06269216596650
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

3.88e-06269229217654
Pubmed

Lysine acetylation regulates Bruton's tyrosine kinase in B cell activation.

BTK EP300

3.88e-06269219949111
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

3.88e-06269220717166
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

3.88e-06269210049825
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

3.88e-06269227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

3.88e-06269229170789
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

3.88e-06269225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

3.88e-06269211559821
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

3.88e-06269221555743
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

3.88e-06269212646247
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

3.88e-06269232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

3.88e-06269219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

3.88e-06269224522976
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

3.88e-06269211867645
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

3.88e-06269221847097
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

3.88e-06269211963968
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

3.88e-06269234813504
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

3.88e-0626929528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

3.88e-06269212696060
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

3.88e-06269220301699
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

3.88e-06269236109165
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

3.88e-06269224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

3.88e-06269237816914
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

3.88e-06269212242694
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

3.88e-06269211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

3.88e-06269210918613
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

3.88e-06269231182547
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

3.88e-06269235502657
Pubmed

Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.

CREBBP EP300

3.88e-06269230635043
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

3.88e-06269231898871
Pubmed

Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.

CREBBP EP300

3.88e-06269227648933
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

3.88e-06269230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

3.88e-06269227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

3.88e-06269219272189
Pubmed

Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.

CREBBP EP300

3.88e-06269210610021
Pubmed

Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.

CREBBP EP300

3.88e-06269237314181
Pubmed

Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.

CREBBP EP300

3.88e-06269212397173
Pubmed

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.

CREBBP EP300

3.88e-06269215641773
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

3.88e-06269232690000
Pubmed

Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.

CREBBP EP300

3.88e-0626929733868
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

3.88e-06269230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

3.88e-06269221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

3.88e-0626929811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

3.88e-06269224089570
Pubmed

Rubinstein-Taybi syndrome in Chinese population with four novel mutations.

CREBBP EP300

3.88e-06269233063428
Pubmed

EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.

CREBBP EP300

3.88e-06269234506759
Pubmed

Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.

CREBBP EP300

3.88e-06269222177454
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

3.88e-06269215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

3.88e-06269239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

3.88e-06269222303793
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

3.88e-06269234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

3.88e-06269234019788
Pubmed

Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior.

PPARGC1A ARHGEF9 CREBBP EP300

4.82e-065669429184203
Pubmed

Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling.

PPARGC1A CREBBP EP300

4.98e-061769328291835
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

PPARGC1A CREBBP EP300

9.69e-062169319596656
Pubmed

Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.

CREBBP EP300

1.16e-05369214716005
Pubmed

NAP1L1 Promotes Endometrial Cancer Progression via EP300-Mediated DDX5 Promoter Acetylation.

NAP1L1 EP300

1.16e-05369238953887
Pubmed

The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.

CREBBP EP300

1.16e-05369218070920
Pubmed

The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression.

CREBBP EP300

1.16e-05369221967847
Pubmed

CBP and p300 are essential for renin cell identity and morphological integrity of the kidney.

CREBBP EP300

1.16e-05369219252086
Pubmed

Glucose-stimulated PGC-1α couples with CBP and Runx2 to mediate intervertebral disc degeneration through transactivation of ADAMTS4/5 in diet-induced obesity mice.

PPARGC1A CREBBP

1.16e-05369236403758
Pubmed

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.

CREBBP EP300

1.16e-05369227903646
Pubmed

Inhibition of p300/CBP by early B-cell factor.

CREBBP EP300

1.16e-05369212748286
Pubmed

Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription.

JAK2 BTK

1.16e-0536927925280
Pubmed

p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively.

CREBBP EP300

1.16e-05369210075656
Pubmed

Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.

CREBBP EP300

1.16e-05369224340053
Pubmed

Associations of genetic variants in the estrogen receptor coactivators PPARGC1A, PPARGC1B and EP300 with familial breast cancer.

PPARGC1A EP300

1.16e-05369216704985
Pubmed

Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response.

CREBBP EP300

1.16e-05369219273602
Pubmed

Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation.

CREBBP EP300

1.16e-05369215649887
Pubmed

Expression patterns of histone acetyltransferases p300 and CBP during murine tooth development.

CREBBP EP300

1.16e-05369222179676
Pubmed

CBP/p300 are bimodal regulators of Wnt signaling.

CREBBP EP300

1.16e-05369217410209
Pubmed

DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.

CREBBP EP300

1.16e-05369226951377
Pubmed

CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.

CREBBP EP300

1.16e-05369221789216
Pubmed

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex.

CREBBP EP300

1.16e-05369212050117
Pubmed

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

CREBBP EP300

1.16e-05369216237459
Pubmed

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.

CREBBP EP300

1.16e-05369212384703
Pubmed

Regulation of transcription factor C/ATF by the cAMP signal activation in hippocampal neurons, and molecular interaction of C/ATF with signal integrator CBP/p300.

CREBBP EP300

1.16e-05369210350644
Pubmed

Loss of p300 and CBP disrupts histone acetylation at the mouse Sry promoter and causes XY gonadal sex reversal.

CREBBP EP300

1.16e-05369229145650
Cytoband9p24

JAK2 ERMP1

6.20e-0586929p24
Cytoband10q24.31

SLF2 CWF19L1

3.74e-041969210q24.31
CytobandEnsembl 112 genes in cytogenetic band chr10q24

SLF2 CWF19L1 STN1

2.95e-03189693chr10q24
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC29 GPSM2 TTC13 TTC9

1.44e-04115424769
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

7.01e-0417422486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

7.87e-041842291
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

BTK ARHGEF9 OSBPL5 DOCK10

1.31e-03206424682
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

JAK2 FRMD6

6.01e-03504221293
GeneFamilyUbiquitin specific peptidases

USP51 USP24

7.49e-0356422366
CoexpressionTRAVAGLINI_LUNG_CILIATED_CELL

USP51 TTC29 VPS35 CEP83 DNAH2 NAP1L1 IFT122 TTC9 TMEM231 SSBP3 PPP1R36 ZMYND12 CSTPP1

4.73e-0610936913M41649
CoexpressionGSE28237_FOLLICULAR_VS_LATE_GC_BCELL_UP

PPARGC1A DOCK10 CHD9 SIM1 CWF19L1 ITPR3

1.43e-05199696M4886
ToppCellDendritic_Cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

JAK2 FLNB RASSF2 DOCK10 ADAM28

3.77e-06151695e089bf197ed60e7243160521d4390d4b40a3832b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-B_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FCRL3 RASSF2 BTK DOCK10 ADAM28

8.16e-06177695b07e6139618d888a9fd7cf43cad0d86a3f63e09e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-B_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FCRL3 RASSF2 BTK DOCK10 ADAM28

8.16e-061776956376ec12322c04d5d37ec2fdc376700464cbc7fb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 ERMP1 LRBA SIM1

9.34e-061826955f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCRL3 ADGRB2 PPP1R36 RSU1 STN1

9.59e-06183695cea27d5e0ec1145d4606c41c18de29035b4aeabe
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse|TCGA-Stomach / Sample_Type by Project: Shred V9

FCRL3 RASSF2 BTK DOCK10

4.83e-051296947d537680b0dfb764f7914d0475c66b678b5cb8d2
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRB2 IFT122 RAB26 ADAM28

5.76e-051356945113bb1713f99d01103b9a99de5d80393081cf87
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BTK DOCK10 TF ADAM28

8.23e-0514869412fa2c4922f03803006c606b1b16e79441e3bb13
ToppCellHippocampus-Macroglia-CSF_related|Hippocampus / BrainAtlas - Mouse McCarroll V32

TTC29 DNAH2 PPP1R36 ZMYND12

9.13e-05152694c2b6cc41546cbd46b9ea5d28a7c66f6330a27df2
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK2 USP51 LRBA PREPL

9.84e-05155694441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

JAK2 RASSF2 TTC29 ADAM28

1.06e-04158694e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCellCiliated_cells-A-HP_01|World / lung cells shred on cell class, cell subclass, sample id

FOLH1 TTC29 DNAH2 PPP1R36

1.09e-041596940c65ae6140abd48c79b04758a6217709ddd15385
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTC29 DNAH2 TF ADAM28

1.22e-04164694e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9

FCRL3 RASSF2 BTK DOCK10

1.31e-04167694d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCell10x5'-Liver-Lymphocytic_B-ABC_aged-B_memory|Liver / Manually curated celltypes from each tissue

FCRL3 BTK NEB ADAM28

1.44e-04171694eb47f4a09a630ed14a0898377039ed50ef7cc292
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JAK2 BTK DOCK10 PLXNA1

1.50e-0417369420f7dfe7d92a3dbec9da9a1f3185aa10cb8f0a3c
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

FCRL3 TMEM231 NEB ADAM28

1.50e-04173694f135cc9dcf34f33ced3210171ab40ae6d77cfae0
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCRL3 BTK CHD9 ADAM28

1.50e-04173694d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

FCRL3 TMEM231 NEB ADAM28

1.50e-0417369423248019c819f6e38337dcc4edb763ef1992e89e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FCRL3 BTK DOCK10 ADAM28

1.60e-04176694274458d80f9f3f080248cbf64e4784ef351e7254
ToppCellBAL-Mild-cDC_3|Mild / Compartment, Disease Groups and Clusters

ARHGEF9 TTC13 IFT122 ADAM28

1.60e-04176694f9b0c3ced391e7ebe6b242d3f12ba14741f88d22
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FCRL3 BTK DOCK10 ADAM28

1.60e-04176694d0a3e176df1270968efa79c00dc941c5e1c4f7aa
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

1.75e-041806949e09b3dfe344b5d50520711513d389865d73a861
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCRL3 BTK DOCK10 ADAM28

1.75e-0418069465c069585737302a69b9a01476f4eb8b50cb2bfd
ToppCellcontrol-Lymphoid-B_cell|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FCRL3 RASSF2 BTK DOCK10

1.79e-04181694e414303bb90e5fe7b667c2acf9a50f8694b90e54
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 DOCK10 CHD9 EP300

1.82e-04182694f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellNS-control-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FCRL3 RASSF2 BTK DOCK10

1.82e-041826944b9b55154a79992112c1c467e8752c3cdbb541d9
ToppCellsevere_influenza-B_intermediate|World / disease group, cell group and cell class (v2)

FCRL3 TTC9 ADAM28 LRRC17

1.82e-04182694e633a908a2fb30ed362cf22fbb8d6839f31f1751
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

1.86e-041836945472cdce6d99314d229418412acf1fff6340db7d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A LOXHD1 FOLH1 NEB

1.90e-041846942cbed6462fea2622871bb7e49b0df3d984239281
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

1.90e-041846945939527d24d299e562e707469c9123890edd76be
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

1.90e-04184694a2191dd5546efd357b23e625beb3c5820476f243
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLF2 DOCK10 CHD9 EP300

1.90e-041846941154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A LOXHD1 FOLH1 NEB

1.90e-04184694ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A LOXHD1 FOLH1 NEB

1.90e-041846942b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FCRL3 BTK DOCK10 ADAM28

1.90e-04184694f81209e6bc01a0140f4487aa8b22eb02fbf0c39c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

1.94e-0418569403f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

DOCK10 RNF213 ERMP1 LRBA

1.94e-04185694a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 DOCK10 CHD9 EP300

1.94e-041856947adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

1.94e-041856941d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

1.94e-04185694b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

1.98e-04186694d57c40b3fe5cfc87e771df76533d9a3e94678b04
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

1.98e-041866941850583d23903d08226aeb0edb3e07b0994330e4
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

1.98e-0418669490eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCellCiliated-cil-1|World / Class top

TTC29 CEP83 PPP1R36 ZMYND12

1.98e-04186694283de646a0e8a322c42a714ae19db9918011146e
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

DOCK10 RNF213 ERMP1 LRBA

1.98e-041866948571956890fc9894d766ba294a28e376b4aba428
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

1.98e-041866944dafc215c42e7949f932a3627359c107943b5d6b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

1.98e-04186694bd8a9753df219084e19e7f94447856e86608325c
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

2.02e-04187694f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCRL3 BTK DOCK10 ADAM28

2.02e-041876948fa454dc4e6a3e8e2bb2ad803acc579e0d3f76da
ToppCellsevere_influenza-B_intermediate|severe_influenza / disease group, cell group and cell class (v2)

FCRL3 TTC9 ADAM28 LRRC17

2.02e-04187694d6db8595aa72fdabc4a056ba6ce09876868a66d5
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

2.02e-0418769497e520705491c8f52a32025311a9fa7b9176979a
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

2.02e-04187694b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCRL3 BTK DOCK10 ADAM28

2.02e-04187694edad646d5eb1d70b768dc21fe02ef5265214e8e6
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

2.06e-0418869414072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

2.06e-0418869460242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP24 DOCK10 RNF213 LRBA

2.06e-04188694ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

2.06e-04188694bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

2.06e-04188694eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

2.06e-04188694b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

TTC29 DNAH2 TMEM231 PPP1R36

2.06e-04188694606907c865bd2f11bb6474932716550f7723d858
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

2.11e-04189694f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

2.11e-0418969470eea8c94fa56bb15bee8065de47acea156794e9
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEST FRMD6 VPS35 PLXNA1

2.11e-0418969409dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCellControl-B_intermediate-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FLNB RASSF2 DOCK10 RNF213

2.11e-0418969411cb9a16f1de8f60af2073ed7ea6d4f41c02f299
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

2.11e-04189694977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

2.11e-04189694975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

2.11e-04189694b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

2.11e-041896947eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellCF-Lymphoid-B_cell|CF / Disease state, Lineage and Cell class

FCRL3 MRPS27 LRBA ADAM28

2.15e-04190694374d8fd63c733178acab07682ed1519693efab45
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A ERMP1 LRBA SIM1

2.15e-04190694c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCellfacs-Lung-nan-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC29 PPP1R36 ADAM28 ZMYND12

2.15e-04190694e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCRL3 DOCK10 RNF213 TTC13

2.15e-04190694d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

2.15e-04190694b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A ERMP1 LRBA SIM1

2.15e-041906945cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCellfacs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC29 PPP1R36 ADAM28 ZMYND12

2.15e-04190694fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOLH1 RASSF2 DOCK10 TF

2.15e-04190694396b7225c2430db3dc55a3d0db70239b71987229
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

2.15e-04190694e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RASSF2 BTK DOCK10 ADAM28

2.19e-04191694baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A ERMP1 LRBA SIM1

2.19e-04191694297bc79adc5fef211497819b4861b52cd26ac754
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A ERMP1 LRBA SIM1

2.19e-04191694e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RASSF2 BTK DOCK10 ADAM28

2.24e-0419269486d792682ba51696f503c79625dd20f87bcf651f
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

RASSF2 SPTLC2 RNF213 ADAM28

2.24e-04192694a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RASSF2 BTK DOCK10 ADAM28

2.24e-04192694d0ad6a205ad50a3c523fa68676996b289eabc5de
ToppCellChildren_(3_yrs)-Immune-monocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

JAK2 RASSF2 DOCK10 ADAM28

2.28e-0419369458e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEST DTWD1 NAP1L1 LRRC17

2.28e-04193694164cc8d51a67c2df3112338acbb1f93c5f838376
ToppCellControl-NK_CD56bright|Control / Disease condition and Cell class

FLNB CHD9 ERMP1 ADAM28

2.28e-041936948b1e7a226a6057e1097c1525984127b54e823876
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RASSF2 BTK DOCK10 ADAM28

2.28e-04193694f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCellCF-Lymphoid|CF / Disease state, Lineage and Cell class

RNASEH2B FCRL3 MRPS27 LRBA

2.28e-0419369411de07d13a7da223990b56fa89ba7fc1c3dd0122
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RASSF2 BTK DOCK10 ADAM28

2.33e-04194694badefcec2af86cbcd97305f4843e84db0f3ebc66
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

RASSF2 SPTLC2 DOCK10 ADAM28

2.33e-04194694ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RASSF2 BTK DOCK10 ADAM28

2.37e-041956942d485373bfd9bb4bb9236bf0b31d03e132c8018f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A LRBA SIM1 CSTPP1

2.37e-041956946477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A USP24 LRBA SIM1

2.37e-04195694a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell(4)_B_follicular|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

FCRL3 BTK NAP1L1 ADAM28

2.37e-04195694defffb7a58a30d2745d2f93dc4aca7be1b53c4ef
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RASSF2 BTK DOCK10 ADAM28

2.42e-041966944370473693d2dd4a8c451a4c477eb79baa33ae12
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FCRL3 BTK DOCK10 ADAM28

2.42e-04196694fc67d8aad1ec4d7f98ffe44fb103e230b9b42c35
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCRL3 USP24 LRBA ADAM28

2.42e-041966940175b097ad1338a07afebe3b5c7fd0bb0bb950f7
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FRMD6 VPS35L VPS41 GPSM2

2.42e-04196694b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_cell-B_naive|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FCRL3 BTK NEB ADAM28

2.42e-04196694de43dd0697e1daf4d50800957cf0b27b54a7a333
Drugdexamethasone; Down 200; 1uM; MCF7; HG-U133A

SPTLC2 CTDP1 NAP1L1 GPSM2 LRBA TIPRL PREPL

2.39e-06199697123_DN
DiseaseMenke-Hennekam syndrome

CREBBP EP300

5.39e-062692cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

5.39e-062692DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

5.39e-062692cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

5.39e-062692C4551859
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

5.39e-062692180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

5.39e-062692cv:C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

5.39e-062692DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

5.39e-062692C0035934
Diseaseautism spectrum disorder (implicated_via_orthology)

NDST1 CHD9 LRBA CREBBP ITPR3

2.93e-05152695DOID:0060041 (implicated_via_orthology)
Diseasemuscle measurement

PLK2 NEB

3.22e-054692EFO_0004515
Diseaseliver cancer (is_marker_for)

JAK2 ADAM28

1.92e-049692DOID:3571 (is_marker_for)
Diseaseattention deficit hyperactivity disorder, asthma

WDPCP ITPR3

2.40e-0410692EFO_0003888, MONDO_0004979
DiseaseDiffuse Large B-Cell Lymphoma

JAK2 CREBBP EP300

2.94e-0455693C0079744
DiseasePrecursor Cell Lymphoblastic Leukemia Lymphoma

JAK2 CREBBP EP300

4.00e-0461693C1961102
DiseaseMeckel-Gruber syndrome

TMEM231 WDPCP

5.55e-0415692C0265215
Diseasediabetic retinopathy (implicated_via_orthology)

PPARGC1A EP300

6.33e-0416692DOID:8947 (implicated_via_orthology)
Diseaseblood urea nitrogen measurement

PPARGC1A SLF2 CHD9 LRBA SIM1 SSBP3

6.63e-04452696EFO_0004741
Diseaseheart disease (biomarker_via_orthology)

JAK2 EP300

7.16e-0417692DOID:114 (biomarker_via_orthology)
DiseaseEye Abnormalities

NDST1 IFT122

7.16e-0417692C0015393
DiseaseMeckel syndrome type 1

TMEM231 WDPCP

8.05e-0418692C3714506
Diseaseglomerulonephritis (is_marker_for)

TF EP300

8.98e-0419692DOID:2921 (is_marker_for)
DiseaseAdenocarcinoma of lung (disorder)

PLK2 TF CREBBP EP300

1.40e-03206694C0152013
Diseasemultisite chronic pain

PLK2 ADGRB2 ITPR3

1.45e-0395693EFO_0010100
DiseaseAdenoid Cystic Carcinoma

CREBBP EP300 FGF16

1.68e-03100693C0010606
Diseasebrain cancer (implicated_via_orthology)

VPS35 GPSM2

1.69e-0326692DOID:1319 (implicated_via_orthology)
DiseaseDrug-Induced Stevens Johnson Syndrome

NUCB1 EP300

2.10e-0329692C1274933
DiseaseToxic Epidermal Necrolysis

NUCB1 EP300

2.10e-0329692C0014518
DiseaseMycoplasma-Induced Stevens-Johnson Syndrome

NUCB1 EP300

2.10e-0329692C3658301
DiseaseStevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum

NUCB1 EP300

2.10e-0329692C3658302
DiseaseStevens-Johnson Syndrome

NUCB1 EP300

2.25e-0330692C0038325
Diseaseceramide measurement

SPTLC2 PSMD3 PPP1R36 PREPL

2.26e-03235694EFO_0010222

Protein segments in the cluster

PeptideGeneStartEntry
EYRYLYLSLREHLAK

ADGRB2

591

O60241
IYLEEILVRVHTDYY

CTDP1

591

Q9Y5B0
ILVRVHTDYYAKYDR

CTDP1

596

Q9Y5B0
RAEYYHLLAEKIYKI

EP300

626

Q09472
HRYYKSALVQIYELE

PRKAG1

96

P54619
DRKVQEHEKYIEYYL

ADAM28

196

Q9UKQ2
LLTVHKLSYYEYDFE

BTK

31

Q06187
SRDEYYHLLAEKIYK

CREBBP

646

Q92793
DLAYVPYYLDLSDHK

C14orf28

236

Q4W4Y0
VEKYRAVYNKLRYEH

CEP83

141

Q9Y592
YIYHTKYDTADRILT

ERMP1

351

Q7Z2K6
LLKYTAQDHSDYRYV

ARHGEF9

256

O43307
HAYYRDAHALLLLYD

RAB26

131

Q9ULW5
NELLLHLKTYNLYYE

RASSF2

21

P50749
VYLYHSLGKSEADYL

JAK2

41

O60674
YEEVHDLERKYAVLY

NAP1L1

96

P55209
HDENVLSYYRYQLKL

ITPR3

721

Q14573
EIQTTIREYYKHLYA

nan

406

O00370
TYTLLQDYEKAIDYH

GPSM2

291

P81274
IYELYSEDLSDMHYR

IFT122

411

Q9HBG6
VYTYLHEKYLDCQER

LRRC17

56

Q8N6Y2
LYHSVYETYELVEKF

FOLH1

551

Q04609
EHEYYKARVYEVVTA

LOXHD1

36

Q8IVV2
RYHFAALEKTYYERL

CWF19L1

191

Q69YN2
LDIIDNYDYSHTVKY

FLNB

896

O75369
ALHEIYSYITKYKDE

PLXNA1

1851

Q9UIW2
YVLAYIDYLSHLNED

CSTF3

446

Q12996
YYRDHNIELSKLLYK

NDST1

851

P52848
YAIFRILLYHAVKYE

LRBA

891

P50851
DTGLYYHRYLQEVID

NUCB1

46

Q02818
SYEEYQHERLKREEY

PPARGC1A

636

Q9UBK2
HIADRDIGIYQYYDK

WDPCP

51

O95876
LDDVAVHYYRLYKDK

FRMD6

226

Q96NE9
VHYYRLYKDKREIEA

FRMD6

231

Q96NE9
LDILEDYLIHKRYLY

CHD9

1211

Q3L8U1
DYLIHKRYLYERIDG

CHD9

1216

Q3L8U1
FKKLSDLYYDIHRSY

DOCK10

1846

Q96BY6
DLYYDIHRSYLKVAE

DOCK10

1851

Q96BY6
DYEYLAQRHVLTYME

CSTPP1

11

Q9H6J7
LALALYRYHSYKDLS

CPD

926

O75976
YHCTAYRKFYILDIE

FCRL3

161

Q96P31
EDRIDYLNDYHTYAV

DNAH2

3656

Q9P225
HDYGDIVAQELLYRY

MEST

146

Q5EB52
IEAIYYFLVDYHTDI

DTWD1

251

Q8N5C7
YFLVDYHTDILKEKY

DTWD1

256

Q8N5C7
NKLSDYYYHADLLSR

OSBPL5

401

Q9H0X9
YYYHADLLSRAAVEE

OSBPL5

406

Q9H0X9
SHVFEYIRSETYKYL

RSU1

231

Q15404
SREEIDHAEYYLYKF

MRPS27

81

Q92552
YREEREIHATTYYKV

STN1

141

Q9H668
AREKLALYVYEYLLH

SSBP3

16

Q9BWW4
LYKHSDSERQYYVAL

FGF16

151

O43320
YALEHLYDSETIRNY

SIM1

716

P81133
SLHLELEKQAYYLTY

SLF2

1076

Q8IX21
RHILELEEVYDYLYQ

RNF213

1266

Q63HN8
EDLLYSEGYLLFYHK

USP51

691

Q70EK9
YLREYSRYLHAHLDT

TTC13

431

Q8NBP0
HDRLDSYSIEKMYYL

ZNF804B

851

A4D1E1
YLYHIDKVDSNDSLY

VPS35L

836

Q7Z3J2
HDRNTYEKYLGEEYV

TF

661

P02787
RNYLHYSLYDQAEKL

PSMD3

256

O43242
EDYIRYAHGLISDYI

RNASEH2B

206

Q5TBB1
KYKAYLYLDEAHSIG

SPTLC2

336

O15270
LYHEADKTYMLREYT

TIPRL

201

O75663
KSYYELYMAISDELH

VPS35

61

Q96QK1
LYMAISDELHYLEVY

VPS35

66

Q96QK1
LLYYLSHYLEKNSLE

PPP1R36

156

Q96LQ0
YYVEHRDDELYILTN

PREPL

301

Q4J6C6
RYHEKQISLYAEYDR

VPS41

611

P49754
LYIAKKNYEEARYHL

ZMYND12

181

Q9H0C1
YDYDLTHIVAAYQER

TMEM231

206

Q9H6L2
RYTYREYLEAHLKFL

USP24

701

Q9UPU5
KLDYLYHYLTRAEDA

TTC29

116

Q8NA56
YHYFEDKENIYILLE

PLK2

146

Q9NYY3
AYDLYKEIVYLQKEH

TMEM260

621

Q9NX78
HLGDYDKALYYLKEA

TTC9

176

Q92623
ERYEDSHLGKYRRIY

TTLL13

466

A6NNM8
YRADYEQRKDKYHLV

NEB

5406

P20929