Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDUF3398

DOCK11 DOCK9

3.01e-056272PF11878
DomainDOCK_C/D_N

DOCK11 DOCK9

3.01e-056272IPR021816
DomainDOCK_C

DOCK11 DOCK9

1.10e-0411272IPR010703
DomainDHR-1_domain

DOCK11 DOCK9

1.10e-0411272IPR027007
DomainDHR_2

DOCK11 DOCK9

1.10e-0411272PS51651
DomainDHR_1

DOCK11 DOCK9

1.10e-0411272PS51650
DomainDOCK-C2

DOCK11 DOCK9

1.10e-0411272PF14429
DomainDHR-2

DOCK11 DOCK9

1.10e-0411272IPR027357
DomainDHR-2

DOCK11 DOCK9

1.10e-0411272PF06920
DomainDOCK

DOCK11 DOCK9

1.10e-0411272IPR026791
Domain-

PAOX KMO

2.95e-03562723.50.50.60
DomainFAD/NAD-binding_dom

PAOX KMO

3.06e-0357272IPR023753
PathwayKEGG_MEDICUS_REFERENCE_CHRNA7_E2F_SIGNALING_PATHWAY

RAF1 RB1

3.47e-056222M47788
PathwayREACTOME_IFNG_SIGNALING_ACTIVATES_MAPKS

IFNGR2 RAF1

4.86e-057222MM17070
PathwayREACTOME_IFNG_SIGNALING_ACTIVATES_MAPKS

IFNGR2 RAF1

6.47e-058222M48010
PathwayKEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_CHRNA7_E2F_SIGNALING_PATHWAY

RAF1 RB1

1.04e-0410222M47789
PathwayWP_MAPK_AND_NFKB_SIGNALING_INHIBITED_BY_YERSINIA_YOPJ

RAF1 TRAF6

1.52e-0412222M39552
PathwayKEGG_COMPLEMENT_AND_COAGULATION_CASCADES

C1S FGG BDKRB2

1.62e-0469223M16894
PathwayBIOCARTA_TID_PATHWAY

IFNGR2 RB1

3.91e-0419222M9546
PathwayREACTOME_INTERFERON_GAMMA_SIGNALING

IFNGR2 RAF1

3.91e-0419222MM15473
Pubmed

Rb-Raf-1 interaction disruptor RRD-251 induces apoptosis in metastatic melanoma cells and synergizes with dacarbazine.

RAF1 RB1

6.25e-07228221139044
Pubmed

A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice.

RAF1 RB1

6.25e-07228218483265
Pubmed

Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulation.

RAF1 RB1

1.87e-0632829819434
Pubmed

Physical mapping confirms that sheep chromosome 10 has extensive conserved synteny with cattle chromosome 12 and human chromosome 13.

GJA3 RB1

1.87e-0632828856922
Pubmed

Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.

DOCK11 DOCK9

1.87e-06328232241915
Pubmed

Bradykinin inhibits oxidative stress-induced senescence of endothelial progenitor cells through the B2R/AKT/RB and B2R/EGFR/RB signal pathways.

RB1 BDKRB2

1.87e-06328226360782
Pubmed

Receptor accessory factor enhances specific DNA binding of androgen and glucocorticoid receptors.

IFNGR2 RAF1

3.75e-0642828349631
Pubmed

Rb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signals.

RAF1 RB1

3.75e-06428210523633
Pubmed

Sorafenib induces growth inhibition and apoptosis in human synovial sarcoma cells via inhibiting the RAF/MEK/ERK signaling pathway.

RAF1 RB1

6.24e-06528219633425
Pubmed

Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation.

RAF1 RB1

6.24e-06528219703998
Pubmed

Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.

DOCK11 DOCK9

6.24e-06528215710388
Pubmed

JNK-binding protein 1 regulates NF-kappaB activation through TRAF2 and TAK1.

RAF1 TRAF6

9.36e-06628219385034
Pubmed

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand.

TRAF6 CTSK

9.36e-06628210097072
Pubmed

The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.

DOCK11 DOCK9

9.36e-06628225851601
Pubmed

Akt regulates vitamin D3-induced leukemia cell functional differentiation via Raf/MEK/ERK MAPK signaling.

RAF1 RB1

1.74e-05828219058874
Pubmed

Gene and pseudogene of the mouse cation-dependent mannose 6-phosphate receptor. Genomic organization, expression, and chromosomal localization.

RAF1 FGG

1.74e-0582821376319
Pubmed

Restricting direct interaction of CDC37 with HSP90 does not compromise chaperoning of client proteins.

RAF1 RB1

1.74e-05828224292678
Pubmed

Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis.

RAF1 RB1

1.74e-05828215485920
Pubmed

Direct interaction of p21 cyclin-dependent kinase inhibitor with the retinoblastoma tumor suppressor protein.

RAF1 RB1

2.80e-051028210486249
Pubmed

Chromosomal assignment of five cancer-associated rat genes: two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma gene.

RAF1 RB1

3.42e-05112821679528
Pubmed

Gene-expression profile of collagen-induced arthritis.

RAF1 CTSK

4.10e-051228211908948
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

FAM200A SIPA1L2 RB1 BDKRB2 SEC11A

4.46e-0549928522810586
Pubmed

Phylogenetic relationships among laboratory and wild-origin Mus musculus strains on the basis of genomic DNA RFLPs.

RAF1 RB1

4.85e-05132827906967
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK11 DOCK9

5.65e-051428212432077
Pubmed

Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities.

SIPA1L2 BDKRB2

9.49e-051828220602751
Pubmed

A major susceptibility locus to murine lung carcinogenesis maps on chromosome 6.

RAF1 RB1

1.06e-04192828499946
Pubmed

Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping.

GJA3 FGG

1.18e-04202821370487
Pubmed

HIV-1-mediated apoptosis of neuronal cells: Proximal molecular mechanisms of HIV-1-induced encephalopathy.

IFNGR2 RB1

1.43e-042228215103018
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

GRIN2B SIPA1L2 DOCK9 JPH3

1.65e-0434728417114649
Pubmed

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.

RAF1 TRAF6 GRIN2B FGG

2.13e-0437128425241761
Pubmed

Identification of differentially expressed genes in mouse spermatogenesis.

MYO7B ZNF347

2.17e-042728214581517
Pubmed

Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays.

RB1 CTSK

2.86e-043128214684825
Pubmed

Characterization of molecules binding to the 70K N-terminal region of fibronectin by IFAST purification coupled with mass spectrometry.

C1S FGG

3.05e-043228223750785
Pubmed

The DNA sequence and analysis of human chromosome 13.

GJA3 RB1 DOCK9

3.44e-0417028315057823
Pubmed

Association of gene polymorphisms with chronic kidney disease in Japanese individuals.

MYO7B JPH3

4.55e-043928219724895
Pubmed

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.

VIL1 MYO7B

6.06e-044528222114352
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOCK11 DOCK9

2.35e-02206212682
GeneFamilyEndogenous ligands

FGG RB1

3.05e-02237212542
CoexpressionHOSHIDA_LIVER_CANCER_SUBCLASS_S3

C1S GCKR FGG ABHD2 KMO

8.42e-06266285M1286
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SIPA1L2 MYO7B DOCK11 KMO

7.14e-06200284a443e475e7a10c26a6173d1af961de6219e0e567
ToppCellLPS_only-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARSF KMO KLHL31

4.70e-051122839801227fe5a6f5ae1b6c5a9e7fa7f35c4c52efe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S GRIN2B MYO7B

1.35e-04160283c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S GRIN2B MYO7B

1.35e-0416028325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-mLTo|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1S CTSK BDKRB2

1.62e-041702837653f1205d4e62abe7e31b1d76f9bbd665e45667
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK9 KLHL31 JPH3

1.71e-041732837dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIL1 FGG MYO7B

1.79e-0417628324eedbbb406d788630bb16678cceef4492d3999c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VIL1 MYO7B DOCK11

1.89e-0417928358ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SIPA1L2 ARSF KMO

1.89e-04179283c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VIL1 ARSF MYO7B

1.98e-041822834a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARSF MYO7B KMO

1.98e-0418228357bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

VIL1 SIPA1L2 MYO7B

2.01e-0418328315d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SIPA1L2 BDKRB2 DOCK9

2.04e-04184283c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIL1 TRAF6 FGG

2.08e-04185283d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FGG SIPA1L2 DOCK11

2.18e-04188283874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FGG SIPA1L2 DOCK11

2.18e-04188283b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellMacrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

SIPA1L2 MYO7B DOCK11

2.21e-04189283c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PAOX TRAF6 MYO7B

2.25e-04190283d0297d678498e346e56cf95fe9e3db7d3ad3b837
ToppCell15-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

C1S DOCK11 CTSK

2.25e-04190283b47472dc9fe6ed99c2365203a3d8a59879e74a70
ToppCell10x5'-Liver-Myeloid_Mac-Macrophage|Liver / Manually curated celltypes from each tissue

IFNGR2 RB1 ZNF347

2.28e-04191283bd7fd445e3d6316d0336c109889e7e6dc394a55e
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.6.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK11 KMO SEC11A

2.32e-04192283b9d6cf6068ffa104968f4944cbf8af6faa2b8942
ToppCell21-Trachea-Epithelial-Epithelial|Trachea / Age, Tissue, Lineage and Cell class

C1S GRIN2B CTSK

2.35e-041932839a8bb44a37f3202e3123a6680bd5545dc91a6d40
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

SIPA1L2 DOCK11 KMO

2.39e-0419428369cf7c989ac355c459db13f9d4267b55adc3c174
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GJA3 C1S SIPA1L2

2.39e-041942831374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCellfacs-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S CTSK BDKRB2

2.42e-0419528318b01ab63ee1deae3cf29669d66fff9ca4efc5c4
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor

SIPA1L2 DOCK11 KMO

2.42e-0419528355e25f702af19146a161861cfd15f40bbda1dc35
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

C1S FGG CTSK

2.46e-04196283988a3e0688e0a7ba69774497d3b130631bb26c50
ToppCellControl_saline-Endothelial-Endothelial-Activated_Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

GRIN2B RB1 BDKRB2

2.54e-041982833c3a5d2555f6af4aa33f9ea778808315d0e39d86
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SIPA1L2 DOCK11 KMO

2.54e-04198283e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SIPA1L2 DOCK11 KMO

2.54e-041982830baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRIN2B CTSK DOCK9

2.54e-0419828302d0d8a212e09c0962ab1dae6a885d26d357f66a
ToppCelldistal-3-mesenchymal-Myofibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WDR91 C1S CTSK

2.57e-041992831f20addc0d138fec02ed6ca4c518169c568de263
ToppCelldistal-3-mesenchymal-Adventitial_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

C1S CTSK BDKRB2

2.57e-04199283547a7c30abc730af2670aee00c7a6af60426c9ac
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuroepithelial-Proteoglycan-expressing_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

C1S CTSK BDKRB2

2.61e-04200283eed2bafddcd041ef5fcc4d1d31edb8be4d83ce01
ToppCelldistal-mesenchymal-Myofibroblast-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WDR91 C1S CTSK

2.61e-04200283069c8949b33ecfdb6da32992002d4060ff6082bc
ToppCellbackground-Hepatocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

C1S FGG ABHD2

2.61e-04200283787d35b5c2f2ad967ae14e99496a0299ac7e72fd
ToppCellLPS_IL1RA|World / Treatment groups by lineage, cell group, cell type

SIPA1L2 BDKRB2 DOCK9

2.61e-04200283a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SIPA1L2 BDKRB2 DOCK9

2.61e-042002832d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuroepithelial|2m / Sample Type, Dataset, Time_group, and Cell type.

C1S CTSK BDKRB2

2.61e-042002833da9441c0f1e242f0d195de47ecd4c24dfdca232
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO7B DOCK11 KMO

2.61e-04200283ed785a6d08ca2b350dc3307b587eadfb2886d1f9
ToppCelldistal-mesenchymal-Myofibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WDR91 C1S CTSK

2.61e-0420028361854a459385cd9295be37157a8f81a2c227dff3
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Slc30a3_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

C1S MYO7B

4.86e-0452282106dd69be38d8ebd298d825c14ac0eefd8366a1a
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Slc30a3_(Deep_layer_pyramidal_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

C1S MYO7B

4.86e-04522829eaf9c1276a3e074cf6c476a419546cbbe4d525c
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Cd9_(Mural.Rgs5Acta2.Cd9)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FGG KLHL31

9.81e-04742827c7e45cf219b0be5cf0d0e5ea5daeb32284c8ccd
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Cd9_(Mural.Rgs5Acta2.Cd9)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FGG KLHL31

9.81e-04742826183baf43010268f54a6db9332296338f4f74009
ToppCelldroplet-Liver-Npc-21m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFNGR2 SIPA1L2

1.01e-03752827f3be37cc378ee115fcb4b0eb9653fc77447aa0a
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat-Inhibitory_Neuron.Gad1Gad2-Chat-Slc17a8.Chat_(cholinergic_interneuron)|Striatum / BrainAtlas - Mouse McCarroll V32

GCKR BDKRB2

1.03e-03762823073a8ace46ad18bddd22ec8f3a1b59ee2fd989d
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat-Inhibitory_Neuron.Gad1Gad2-Chat-Slc17a8.Chat_(cholinergic_interneuron)-|Striatum / BrainAtlas - Mouse McCarroll V32

GCKR BDKRB2

1.03e-03762823f5865b9cb6648b88eb873018e513c5efb457ae5
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Cacng4_(Non-anterior_nuclei)|Thalamus / BrainAtlas - Mouse McCarroll V32

GCKR KMO

1.03e-03762824afc8d0e79870c635a89dd8e7ca91ebfe482b4ab
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat|Striatum / BrainAtlas - Mouse McCarroll V32

GCKR BDKRB2

1.03e-0376282041a8984b3ae4bb03ae6db8234c1333ac73098fa
ToppCellPND07-28-samps-Myeloid-Macrophage-macrophage-C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MYO7B JPH3

1.15e-03802823413ac5e1c1e59eab6a83b889b870a8db4efccb9
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

GCKR BDKRB2

1.26e-03842829417fffe0ba79f5851920258dcd0f6c09218be13
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

C1S KLHL31

1.41e-038928242432936a6b4289cc4b42fcb576fb09073f2264b
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

C1S KLHL31

1.41e-03892826c594e13f169970b337c2fc3ab969faf6db1a27a
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6|Thalamus / BrainAtlas - Mouse McCarroll V32

GCKR GRIN2B

1.78e-031002821de3895e16f14ff32b901b18ce14d965afaa7e76
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Thalamus / BrainAtlas - Mouse McCarroll V32

GCKR GRIN2B

1.78e-0310028220675fc2ffc5ab63047d38da083b50d470f3db19
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora|Thalamus / BrainAtlas - Mouse McCarroll V32

GCKR GRIN2B

1.78e-03100282ff1bdb511700a041a90034d1d30dfc25f51d6c82
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Desmoid_Tumor|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

GCKR JPH3

2.51e-03119282d8fbea9ded96fcc3ebdfb4d28873c563427ce811
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Desmoid_Tumor-7|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

GCKR JPH3

2.51e-031192829e38f13bf98b9ee44b178300e6f80fd08a006296
ToppCellControl-Endothelial-Endothelial-Activated_Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GCKR BDKRB2

2.59e-03121282a5962d1c476e6966870832b72d511607e047248b
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-5|TCGA-Breast / Sample_Type by Project: Shred V9

FGG KMO

2.72e-0312428274f756a50036bd2a825f359529da4fbf691e64f0
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Undifferentiated_Pleomorphic_Sarcoma-7|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

WDR91 ABHD2

2.85e-03127282c4809d8502f460370f824719d69b13b400a2b202
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

C1S CTSK

2.94e-0312928213cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-C1ql2-Excitatory_Neuron.Slc17a7.C1ql2-Cck_(Dentate_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

XRRA1 FGG

2.94e-0312928208ecebb7f09d105dfdfd2191fc310910d3baec0f
ToppCellTCGA-Mesothelium|World / Sample_Type by Project: Shred V9

DOCK11 KLHL31

2.98e-031302823ef1733eb57e2a9a3298ce0d65401f19e2084df1
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIN2B JPH3

3.16e-0313428264979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

KLHL31 JPH3

3.30e-03137282ed81624b9167255ce88dcf6ad7f1636376ea0525
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-8|TCGA-Lung / Sample_Type by Project: Shred V9

VIL1 FGG

3.30e-0313728205ca83c30e3dbe74c81278b3636d57da2c20b458
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

KLHL31 JPH3

3.30e-0313728247859aa25f32367461c1ec75ed9060bee430c6b7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIN2B JPH3

3.40e-03139282c9bf98bed77415a1438f3f9e441a1346e75c26b0
ToppCellTCGA-Bile_Duct|World / Sample_Type by Project: Shred V9

GCKR FGG

3.45e-03140282ca8a0ccbc2f501b759864fe9bb06dc8b44b6b31f
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|367C / Donor, Lineage, Cell class and subclass (all cells)

IFNGR2 VIL1

3.49e-03141282e409da87da5a38ba4d0ccc5e3f8bd89f480f9dab
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIN2B JPH3

3.54e-031422825690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIPA1L2 CTSK

3.59e-0314328239060dc1d87505a16e2df95140087c731f099570
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma_Heterologous_Type-3|TCGA-Uterus / Sample_Type by Project: Shred V9

VIL1 MYO7B

3.59e-03143282bcf702f976ab91f82a5a4beb0b7c74a372c42ae6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VIL1 DOCK11

3.59e-031432828f897278f9ccc82ae35e4f30c5f930b2a3eb509d
ToppCellCOVID-19-Mast_cells-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

BDKRB2 JPH3

3.69e-031452825c5fed4620c4c312d1052b8acad910453f7e8fcc
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma-3|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

VIL1 MYO7B

3.74e-03146282e55b4acecf4e363b5afa287c747c2e58c4597f3a
ToppCelldroplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S FGG

3.79e-0314728200619115b9a1ec2b967c2992043b41974ece63c4
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1S GRIN2B

3.84e-031482825983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCellE16.5-samps-Mesenchymal-Pericyte-pericyte_A|E16.5-samps / Age Group, Lineage, Cell class and subclass

C1S DOCK11

3.84e-03148282c87fe2373418ec0cfe37279003d1c4df4c0d0aac
ToppCellE16.5-samps-Mesenchymal-Pericyte|E16.5-samps / Age Group, Lineage, Cell class and subclass

C1S DOCK11

3.84e-03148282e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

VIL1 MYO7B

3.89e-0314928292a8931a51db619fb5f0638d319c02e7838f6559
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GCKR SIPA1L2

3.89e-0314928224a7538b54b2a5291503c7493fefed4e45e8d710
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GCKR SIPA1L2

3.89e-03149282cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S FGG

3.99e-03151282cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S FGG

3.99e-03151282e243b6c76e59035f10519a86399b598dd2123f87
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S FGG

3.99e-03151282cdd2ce0969da446616627e3569bbe5a5d9b475bd
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic-naive_B_cell|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RB1 MYO7B

3.99e-031512820f8f07e44c6edaf09574930b416fdce14d67095a
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_3|390C / Donor, Lineage, Cell class and subclass (all cells)

VIL1 KMO

4.05e-03152282f717aae4882e9b67e5e40f4ef5b0d35f74a89165
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYO7B DOCK11

4.05e-031522820652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARSF KMO

4.05e-0315228288a810d41edb5a917c23cb5ba5a387227e1312cb
ToppCell367C-Fibroblasts-Fibroblast-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

C1S CTSK

4.15e-03154282dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell367C-Fibroblasts-Fibroblast-D|367C / Donor, Lineage, Cell class and subclass (all cells)

C1S CTSK

4.15e-031542824bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_ACHE|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO7B KMO

4.15e-0315428287de3be89e92d2e3980eaf973ee729ad871342aa
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd|Liver / Manually curated celltypes from each tissue

XRRA1 CTSK

4.15e-03154282c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCellPBMC-Mild-cDC_6|Mild / Compartment, Disease Groups and Clusters

RAF1 TRAF6

4.26e-031562823db686849844120b3e376599929d11ad06f0d577
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

C1S ARSF

4.26e-03156282bb505f639dbcad2b788db62d6084c2cb4e884bec
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCKR FGG

4.31e-03157282b6ecf1d8c6a465ff31cbc181e00ea88b76b38e19
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCKR FGG

4.31e-0315728201ad5cbaf91010e79216e1fb37b7b890618c5f28
DiseaseMechanical Allodynia

RAF1 GRIN2B BDKRB2

5.52e-0584263C2936719
DiseaseAllodynia

RAF1 GRIN2B BDKRB2

5.52e-0584263C0458247
DiseaseHyperalgesia, Secondary

RAF1 GRIN2B BDKRB2

5.52e-0584263C0751212
DiseaseHyperalgesia, Primary

RAF1 GRIN2B BDKRB2

5.52e-0584263C0751211
DiseaseHyperalgesia, Thermal

RAF1 GRIN2B BDKRB2

5.52e-0584263C0751214
DiseaseTactile Allodynia

RAF1 GRIN2B BDKRB2

5.52e-0584263C0751213
DiseaseHyperalgesia

RAF1 GRIN2B BDKRB2

5.52e-0584263C0020429
DiseaseBMI-adjusted leptin measurement

GCKR KLHL31

7.78e-0515262EFO_0007793
Diseaseprotein C measurement

GCKR MYO7B

1.01e-0417262EFO_0004633
Diseaseprothrombin time measurement

GCKR FGG

1.55e-0421262EFO_0008390
Diseaseinsulin sensitivity measurement

IFNGR2 GCKR

1.87e-0423262EFO_0004471
Diseasepartial thromboplastin time

C1S FGG

2.04e-0424262EFO_0004310
Diseaseglycerol measurement

SIPA1L2 HERC2P3

2.40e-0426262EFO_0010115
DiseaseIschemic stroke, factor VII measurement

GCKR JPH3

2.99e-0429262EFO_0004619, HP_0002140
Diseaseresponse to bronchodilator, FEV/FEC ratio

GCKR GRIN2B RB1 CTSK JPH3

4.87e-04766265EFO_0004713, GO_0097366
Diseasevenous thromboembolism, factor VII measurement

GCKR FGG

5.15e-0438262EFO_0004286, EFO_0004619
DiseaseHypotension

GRIN2B BDKRB2

1.00e-0353262C0020649
Diseaseserum gamma-glutamyl transferase measurement

C1S GCKR SIPA1L2 DOCK11 JPH3

1.08e-03914265EFO_0004532
Diseasefatty acid measurement, linoleic acid measurement

C1S GCKR

1.64e-0368262EFO_0005110, EFO_0006807

Protein segments in the cluster

PeptideGeneStartEntry
VGYGIQKGNKHWIIK

CTSK

281

P43235
KKQGYSTGLIGKWHQ

ARSF

126

P54793
KKSWEVYQGVCQKGG

BDKRB2

341

P30411
IWGKSGHIQTALYGK

ABHD2

71

P08910
LGQYKLNWKHCKGIS

FAM200A

196

Q8TCP9
GVLGGYIQKKKELWG

RB1

86

P06400
GTVYKGKWHGDVAVK

RAF1

361

P04049
GGWNEGEKKYKKCIQ

KLHL31

571

Q9H511
KKGHVYLVGWQTLGI

GCKR

326

Q14397
KKNWIQYKEGFGHLS

FGG

231

P02679
HWQKKVINKGLFFLG

KMO

416

O15229
SQKGGVIKQGWLHKA

DOCK11

161

Q5JSL3
QKGGITKHGWLYKGN

DOCK9

171

Q9BZ29
LTGQKKGWKLRYHGD

C1S

276

P09871
YVHYWEKGGIQQVKG

IFNGR2

176

P38484
EIYHLGWKKLKQGVT

GJA3

221

Q9Y6H8
GEYLKKEIGQHVAGW

PAOX

156

Q6QHF9
GAVNKYVIGWKKSEG

SIPA1L2

1391

Q9P2F8
TGVHKYKWLKQNVQG

HERC2P3

341

Q9BVR0
GGLKIYVWKGKKANE

VIL1

291

P09327
GIYIWKIGNFGMHLK

TRAF6

351

Q9Y4K3
YKQGQHWLEKKDVVG

SEC11A

126

P67812
IHTGGKPYKCNVWKV

ZNF347

811

Q96SE7
GKFIQWNIHKSGLKV

WDR91

626

A4D1P6
EGQGHWLVVQKGNLK

XRRA1

31

Q6P2D8
HGIGLESKGKWVYKG

JPH3

71

Q8WXH2
GIYGHLFLWIVKKIN

MYO7B

401

Q6PIF6
VTNGKHGKKINGTWN

GRIN2B

481

Q13224