Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentcostamere

AHNAK CMYA5 SDC4

3.68e-0522623GO:0043034
DomainFN3

MPL ATF7IP IL20RA CMYA5 TNXB

5.16e-04199625PS50853
DomainFN3_dom

MPL ATF7IP IL20RA CMYA5 TNXB

6.45e-04209625IPR003961
DomainNicotinic_acetylcholine_rcpt

CHRNB3 CHRNE

1.26e-0316622IPR002394
Domain-

MPL ATF7IP GPCPD1 IL20RA CMYA5 IL18RAP TNXB ALPK2

1.51e-036636282.60.40.10
DomainIg-like_fold

MPL ATF7IP GPCPD1 IL20RA CMYA5 IL18RAP TNXB ALPK2

2.23e-03706628IPR013783
Domain-

CHRNB3 CHRNE

2.62e-03236221.20.120.370
DomainAcetylcholine_rcpt_TM

CHRNB3 CHRNE

2.62e-0323622IPR027361
DomainNeurotransmitter_ion_chnl_CS

CHRNB3 CHRNE

9.79e-0345622IPR018000
Pubmed

AUF1 contributes to Cryptochrome1 mRNA degradation and rhythmic translation.

RPS3 EIF4G1 CRY1

5.93e-08564324423872
Pubmed

A DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulator.

TOPBP1 TOP2B

3.33e-0626429461304
Pubmed

Syndecan-4 regulates ATF-2 transcriptional activity in a Rac1-dependent manner.

ATF2 SDC4

9.99e-06364215371457
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

BDP1 CASP8AP2 RESF1 ATF7IP TOPBP1 SECISBP2 LRIF1 STAT2

1.23e-0558864838580884
Pubmed

IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling.

IL20RA STAT2

2.00e-05464237884352
Pubmed

A human MAP kinase interactome.

CCDC14 CASP8AP2 TSC22D1 ATF7IP HERPUD1 COG4 MSL2

3.11e-0548664720936779
Pubmed

E3 ubiquitin ligase RBX1 drives the metastasis of triple negative breast cancer through a FBXO45-TWIST1-dependent degradation mechanism.

ATF2 CRBN

4.98e-05664235802537
Pubmed

Human transcription factor protein interaction networks.

ZNF536 NOP14 RESF1 PITRM1 RBM27 ATF7IP BCL7B EIF4G1 TADA3 LRIF1 STAT2

5.44e-051429641135140242
Pubmed

Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates.

CASP8AP2 TOP2B ADD3

6.03e-054164315561718
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

ARFGAP2 AHNAK EIF4G1 NHS SRGAP2 STAT2 ADD3

8.03e-0556564725468996
Pubmed

Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.

ARFGAP2 RPS3 AHNAK EIF4G1 TOP2B

9.05e-0524564521182205
Pubmed

Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter.

RPS3 CRY1

9.27e-05864219129230
Pubmed

Deubiquitinase OTUD6A promotes breast cancer progression by increasing TopBP1 stability and rendering tumor cells resistant to DNA-damaging therapy.

TOPBP1 TOP2B

9.27e-05864235768646
Pubmed

Allelic variants between mouse substrains BALB/cJ and BALB/cByJ influence mononuclear cardiomyocyte composition and cardiomyocyte nuclear ploidy.

NHS GDI1

9.27e-05864232371981
Pubmed

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.

TSC22D1 RPS3 EIF4G1 GDI1 TOP2B

1.45e-0427164525737280
Pubmed

The chromosomal mapping of four genes encoding winged helix proteins expressed early in mouse development.

MPL FOXC2

1.49e-04106428661058
Pubmed

Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes.

RPS3 EIF4G1

1.49e-041064212388085
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

TSC22D1 EIF4G1 GPCPD1 NASP GDI1 NACAD HERPUD1 COG4 LRIF1

2.08e-04112464921900206
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

AHNAK BCL7B EIF4G1 TOPBP1 CRBN TOP2B NUFIP1 MSL2 CRY1

2.54e-04115564920360068
Pubmed

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates.

ATF2 TOP2B

2.57e-04136429155018
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

CCDC14 AFAP1L2 SRGAP2 GDI1 LRIF1 NUFIP1 FOXC2

2.71e-0468964736543142
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

AFAP1L2 TOP2B NUFIP1 FOXC2

2.85e-0417164420201926
Pubmed

Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties.

CHRNB3 CHRNE

2.99e-041464219059502
Pubmed

Analysis of nicotinic acetylcholine receptor subunits in the cochlea of the mouse.

CHRNB3 CHRNE

3.45e-04156428838678
Pubmed

Quantitative trait loci affecting initial sensitivity and acute functional tolerance to ethanol-induced ataxia and brain cAMP signaling in BXD recombinant inbred mice.

SLC6A4 CHRNE

3.45e-041564212183685
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

RBM27 RPS3 ATF7IP AHNAK EIF4G1 TOPBP1 TADA3 TOP2B

3.54e-0495464836373674
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

RBM27 AHNAK EIF4G1 SECISBP2 SRGAP2 TADA3 TOP2B

3.65e-0472464736232890
Pubmed

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.

CHRNB3 CHRNE

3.93e-041664219259974
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

ARFGAP2 PITRM1 RPS3 AHNAK EIF4G1 STAT2

4.67e-0453864628524877
Pubmed

Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis.

RPS3 NASP ATF2

5.09e-048464319135240
Pubmed

Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection.

SLC40A1 STAT2

5.59e-041964232075740
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

CASP8AP2 RBM27 AHNAK TOPBP1 ATF2 TADA3 LRIF1 TOP2B MSL2

5.80e-04129464930804502
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

ARFGAP2 NOP14 EIF4G1 TOPBP1 ADD3

6.05e-0437064522922362
Pubmed

PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis.

NOP14 RPS3 TOP2B

6.23e-049064330699358
Pubmed

ATRX proximal protein associations boast roles beyond histone deposition.

ZNF536 NOP14 LRIF1

6.43e-049164334780483
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

AHNAK EIF4G1 NASP RPL3L

6.75e-0421564435973513
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

NOP14 RESF1 TOPBP1 LRIF1

7.61e-0422264437071664
Pubmed

Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.

NOP14 RPS3 AHNAK EIF4G1

7.73e-0422364420020773
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NOP14 RESF1 RBM27 BCL7B ATF2 TADA3 LRIF1 TOP2B

9.16e-04110364834189442
Pubmed

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.

RPS3 EIF4G1 NASP GDI1 RPL3L

9.68e-0441164536652389
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

ZNF536 NOP14 RPS3 EIF4G1 ATF2 TOP2B FOXC2

9.87e-0485764725609649
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

ATF7IP AHNAK TOP2B

1.00e-0310664319394292
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CASP8AP2 ZNF536 RESF1 ATF7IP AHNAK

1.04e-0341864534709266
Pubmed

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.

RBM27 AHNAK NASP CRY1

1.10e-0324564435652658
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

CCDC14 RBM27 AHNAK TOPBP1 NASP LRIF1

1.20e-0364564625281560
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NOP14 TTC16 AHNAK EIF4G1 GATB RPL3L SH3D21 TOP2B CHRNB3

1.25e-03144264935575683
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

RBM27 AHNAK EIF4G1 NASP

1.29e-0325664433397691
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

RESF1 AHNAK EIF4G1 TOP2B ADD3

1.36e-0344464534795231
Pubmed

Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.

ADD3 FOXC2

1.40e-033064229555813
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

ARFGAP2 RPS3 AHNAK EIF4G1 NASP

1.43e-0344964531732153
Pubmed

Mapping the Genetic Landscape of Human Cells.

BDP1 PITRM1 EIF4G1 GATB CENPK

1.46e-0345164530033366
Pubmed

Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening.

AHNAK FOXC2

1.50e-033164232546759
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

TSC22D1 NOP14 RBM27 RPS3 AHNAK EIF4G1 HERPUD1 TOP2B

1.59e-03120364829180619
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RBM27 ATF7IP AHNAK NASP SRGAP2 TOP2B ADD3

1.62e-0393464733916271
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

NOP14 RBM27 RPS3 EIF4G1

1.65e-0327464434244482
Pubmed

ROR2 Downregulation Activates the MSX2/NSUN2/p21 Regulatory Axis and Promotes Dental Pulp Stem Cell Senescence.

RPS3 EIF4G1 NASP

1.84e-0313164335356984
Cytoband2q32

ATF2 SLC40A1

1.72e-04146422q32
Cytoband13q14

TSC22D1 NUFIP1

4.75e-042364213q14
GeneFamilyFibronectin type III domain containing

MPL ATF7IP PTPRQ CMYA5 TNXB

2.02e-05160385555
GeneFamilyCholinergic receptors nicotinic subunits

CHRNB3 CHRNE

5.07e-0416382173
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL20RA IL18RAP

3.51e-0342382602
CoexpressionPYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP

CCDC14 CASP8AP2 TOPBP1 NASP CENPK MSL2

8.22e-06195646M13736
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

BDP1 RESF1 RBM27 RPS3 ATF7IP AHNAK GPCPD1 SECISBP2 IL18RAP GDI1 ATF2 CRBN TOP2B

5.39e-0514926413M40023
CoexpressionMENON_FETAL_KIDNEY_0_CAP_MESENCHYME_CELLS

CCDC14 BDP1 NASP TOP2B

7.05e-0590644M39250
CoexpressionGSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN

TSC22D1 AHNAK SLC40A1 STAT2 MX2

7.33e-05177645M7632
CoexpressionGSE3982_MEMORY_CD4_TCELL_VS_TH2_UP

TSC22D1 TNXB MX2 ADD3 MSL2

1.18e-04196645M5381
CoexpressionGSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_DN

NASP SRGAP2 CTNS STAT2 MX2

1.21e-04197645M6835
CoexpressionGSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP

TSC22D1 DCBLD1 CTNS CDH7 SDC4

1.24e-04198645M6112
CoexpressionGSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_UP

RBM27 GDI1 HERPUD1 TOP2B ADD3

1.27e-04199645M6443
CoexpressionGSE30083_SP3_VS_SP4_THYMOCYTE_DN

ZNF536 AHNAK IL18RAP SDC4 MX2

1.30e-04200645M5037
CoexpressionGSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP

TSC22D1 NASP SRGAP2 CMYA5 ATF2

1.30e-04200645M7795
CoexpressionGSE36527_CD62L_HIGH_VS_CD62L_LOW_TREG_CD69_NEG_KLRG1_NEG_UP

RESF1 TOPBP1 IL18RAP STAT2 MX2

1.30e-04200645M9023
CoexpressionGSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP

CASP8AP2 TSC22D1 TOPBP1 NASP ADD3

1.30e-04200645M4456
CoexpressionGSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_UP

AHNAK GPCPD1 GDI1 TOP2B CRY1

1.30e-04200645M5630
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5

BDP1 CASP8AP2 ZNF536 NASP NHS CENPK

1.55e-05186616Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 RESF1 ATF7IP AHNAK STAT2 MX2

4.33e-0720064612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellfacs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK CMYA5 SDC4 STAT2

6.27e-06181645782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCellfacs-Marrow-B-cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK CMYA5 SDC4 STAT2

6.27e-06181645e2481291c236105774c53883e6f20da11941df9b
ToppCellfacs-Skin-Anagen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 TSC22D1 IL20RA HERPUD1 SH3D21

6.44e-0618264522d6f4790950508e8aa27e02a8133af5f53f13c8
ToppCellfacs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 TSC22D1 IL20RA TNXB HERPUD1

7.35e-061876459c1013720c248ef201d010806b6e7ad24205e8ee
ToppCellfacs-Skin-Telogen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 TSC22D1 IL20RA TNXB HERPUD1

7.54e-061886458cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCellCaecum-T_cell-Activated_CD4_T|T_cell / Region, Cell class and subclass

RESF1 RPS3 GPCPD1 MX2 ADD3

9.93e-0619964513173cc4dcc8e856680372b0a4ad4f36afa892c1
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature|E16.5-samps / Age Group, Lineage, Cell class and subclass

TTC16 CMYA5 TADA3 TNXB

3.59e-051296445e4783cc63afdeaebdfaecb72f95f3efc8d3c4a3
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A4 SRGAP2 STAT2 FOXC2

6.97e-05153644991782d111d66e25b40319d4e6dea40f2c2c0805
ToppCellICU-NoSEP-Lymphocyte-T_NK-MAIT|ICU-NoSEP / Disease, Lineage and Cell Type

AFAP1L2 EFCAB13 DCBLD1 CTNS

9.56e-05166644d3fa2e42497201f1ca57f4f977fbaa0def950033
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MPL PTPRQ CMYA5 RPL3L

9.78e-05167644d78356bf0c473816dbabaee51984940bd822f84e
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

ZNF536 AFAP1L2 TNXB FOXC2

9.78e-05167644d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCellRSV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

AHNAK STAT2 MX2 MSL2

1.17e-04175644ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCellRSV-Healthy-1|RSV / Virus stimulation, Condition and Cluster

AHNAK STAT2 MX2 MSL2

1.17e-04175644ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCellfacs-Skin-nan-24m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 TSC22D1 RPS3 TNXB

1.17e-0417564421542be95059983d2c8bdf01ec711fdbf1ec1f62
ToppCellASK452-Immune-T_cell|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

RESF1 RPS3 IL18RAP CENPK

1.20e-0417664451cafa10f2569f5909bb84b134e68c61abca8a13
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATF7IP AHNAK CMYA5 TOP2B

1.20e-04176644749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 NHS SLC40A1 CHRNB3

1.22e-04177644fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFAP1L2 NASP CENPK CHRNE

1.22e-041776444553ee8cd9c24db6511b09fe49ed11a89e7cde9e
ToppCellfacs-Marrow-KLS-24m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 IL20RA CENPK RPL3L

1.28e-041796445297f7459b40ca780a1983fecc1bb9c035c7677e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 PTPRQ SRGAP2 CMYA5

1.28e-041796447394e77e665bf16d3733df91bb12907be460ab44
ToppCellILEUM-non-inflamed-(7)_Lymphatics|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CMYA5 TNXB ADD3 FOXC2

1.28e-0417964499777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPL SLC6A4 ZNF536 AFAP1L2

1.39e-04183644876b4f128c2168fdae7488201ff44f19c06c8415
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPL SLC6A4 ZNF536 AFAP1L2

1.39e-04183644b190b650e61b1b20baf5e42d04acac82d3fd1400
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK GPCPD1 SLC40A1

1.45e-041856447f46ea82a663181957f88e4e83114aef8a78820c
ToppCelldroplet-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AFAP1L2 SH3D21 FOXC2

1.45e-04185644eeb6f55a6f79adf80247baa2c4b0df44553557ad
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 NHS CDH7 CHRNB3

1.45e-04185644487fa382232564f075960899d50afa0edae5d258
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK GPCPD1 SLC40A1

1.45e-04185644956fb0043c0c3e4e5c4d6f58ff95faf6209c380e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 NHS SLC40A1 CDH7

1.45e-04185644e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK GPCPD1 SLC40A1

1.48e-04186644ba6ba75218efc26371cea24ddbb0e9b3e3f421ac
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK GPCPD1 SLC40A1

1.48e-04186644a58c9d1567da0961e0e295a156773d2252ee5a1a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK GPCPD1 SLC40A1

1.48e-0418664465e25a9dcef5fc71510aaf170e220deef5b2feb2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK GPCPD1 SLC40A1

1.48e-04186644e4f1259725160719e5fd13d76e5a707efed70013
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DCBLD1 GPCPD1 LRRC37B SDC4

1.51e-04187644c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 NHS CDH7 CHRNB3

1.51e-0418764402105c82a9ba79d2f19e002188377fc3440770c2
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK GPCPD1 SLC40A1

1.54e-041886444dc89c7843ebd078e3414e835c56f11fa27f0c5f
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK GPCPD1 SLC40A1

1.54e-04188644d577b3c2a844e3062c7ca9e9ebc1722d0ac95caa
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK GPCPD1 SLC40A1

1.54e-041886441e788b60dd643bf220d8dfafa82d85fd083cbc71
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

DCBLD1 GPCPD1 LRRC37B SDC4

1.57e-0418964499b01893da9f9f7c9528afaffad178285211738b
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 TSC22D1 IL20RA TNXB

1.57e-041896441cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCell3'_v3-Lung-Lymphocytic_T_CD8-Trm/em_CD8|Lung / Manually curated celltypes from each tissue

RESF1 RPS3 ATF7IP HERPUD1

1.61e-0419064474638e470ece8016465bbebc1756ffa6d605b25f
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CMYA5 TNXB ADD3 FOXC2

1.61e-041906449ce301841ce9486701fa28eb2a9929e35d476878
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 NHS SLC40A1 CDH7

1.61e-041906440acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 TNXB ALPK2 ADD3

1.64e-041916449214655dca96d766737c9f30b624d7fe7050342e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK GPCPD1 SLC40A1

1.67e-041926449d53b42cdb537b30233cdfdc08052c8b13a1113f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK GPCPD1 SLC40A1

1.67e-04192644042391162df2e3d0027688dd14163c4c6821afe0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 AHNAK GPCPD1 SLC40A1

1.67e-0419264471b0bfee0461ff64cef35881db3959c517e9731b
ToppCellControl-PLT_1|World / Disease Group and Platelet Clusters

SLC6A4 TSC22D1 SLC40A1 SDC4

1.67e-04192644f595eba81911eb860dce964f1d8269287f50d3ea
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CMYA5 TNXB ADD3 FOXC2

1.67e-04192644d43caf42ec744e895137f31ef65a990e250669d2
ToppCellhealthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

RESF1 TTC16 RPS3 AHNAK

1.81e-04196644af00c31612e4fe068e5fccae05368edba46bbd20
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CASP8AP2 TOPBP1 NASP CENPK

1.81e-04196644df366d76ea55f49e349d622effa57c1535df8400
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RESF1 TTC16 RPS3 AHNAK

1.81e-04196644578afe58962a24874b99b0407a647b12e972344b
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RESF1 RPS3 ATF7IP IL18RAP

1.81e-041966444a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

RESF1 TTC16 AHNAK ADD3

1.84e-04197644836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCellmLN-T_cell-Th1|T_cell / Region, Cell class and subclass

AHNAK IL18RAP HERPUD1 SDC4

1.84e-041976445e39a49dddef04469ff2b615d755ddf6a926e58e
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF536 NHS CDH7 ALPK2

1.84e-04197644dfeb4a0eb4dfba90f4a3e6ba31e0ab0e4aba5849
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TTC16 RPS3 AHNAK ADD3

1.88e-0419864488bb764b21ca50e56f6c536a2d61d35afd8c3f36
ToppCell(1)_T_cell-(14)_Tcm|(1)_T_cell / shred on Cell_type and subtype

RPS3 NHS SLC40A1 ADD3

1.88e-0419864440d9adb32247ab18db21a0f215b99a29b9a839b7
ToppCellmLN-T_cell-Th17|mLN / Region, Cell class and subclass

AHNAK IL18RAP SDC4 CRY1

1.88e-0419864404905f62941b193864704a10ad692faf777fa51d
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

SLC6A4 AHNAK IL18RAP MX2

1.88e-0419864476d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCellmLN-(1)_T_cell-(13)_Th17|mLN / shred on region, Cell_type, and subtype

AHNAK IL18RAP SDC4 CRY1

1.88e-04198644c575e9aeee4e034e8c4d171fe754403652343731
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

AHNAK GPCPD1 STAT2 MX2

1.88e-0419864461ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4|GI_small-bowel / Manually curated celltypes from each tissue

AHNAK IL18RAP SDC4 CRY1

1.88e-041986446333e46cd1ccf5841ce15aea98a4b2f5e3ae4675
ToppCellLAM-Endothelial-VasEndo-2|Endothelial / Condition, Lineage and Cell class

SLC6A4 TSC22D1 IL20RA HERPUD1

1.88e-0419864492bccaec01f1dbb17d5efcba30f7f800f674ca96
ToppCellcontrol-Platelet|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC6A4 TSC22D1 TNXB SLC40A1

1.88e-04198644fc066f428340478605e7d9ff3c0c645c427c4876
ToppCellCaecum-T_cell-Activated_CD4_T|Caecum / Region, Cell class and subclass

RESF1 RPS3 MX2 ADD3

1.95e-042006447de96254a51dee1375a34b5ae680fe9cce1dbebf
ToppCellCOVID-19_Moderate-CD4+_CTL|COVID-19_Moderate / disease group, cell group and cell class

TTC16 RPS3 AHNAK IL18RAP

1.95e-04200644a9c73559e2c9fda1b065bfb5ce84978995505924
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2--L2-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

ZNF536 NHS SLC40A1 CDH7

1.95e-04200644c65e6336725856c4b5f6aeba1cf86a23ec815d34
ToppCellsevere-CD8+_Tem|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TTC16 RPS3 AHNAK HERPUD1

1.95e-04200644aaa2cd326dc15dee2fd975ca133359c5826f6a75
ToppCellVE|World / Condition, Cell_class and T cell subcluster

RESF1 NASP STAT2 MX2

1.95e-042006448ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellhealthy_donor|World / Disease condition, Lineage, Cell class and subclass

RESF1 RPS3 AHNAK IL18RAP

1.95e-04200644afd4d5609adaa470e3d880f8be4a4d55e162b3d6
ToppCellCaecum-(1)_T_cell-(11)_Activated_CD4_T|Caecum / shred on region, Cell_type, and subtype

RESF1 RPS3 MX2 ADD3

1.95e-04200644aef861cb03dd4eb6c571af1f7c32fc0166b50b2c
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ZNF536 NHS SLC40A1 CDH7

1.95e-04200644117a25b3b9cdbc2e198381350a8362bee25e82e7
ToppCellTransverse-T_cell-Activated_CD4_T|T_cell / Region, Cell class and subclass

RPS3 GPCPD1 CRBN ADD3

1.95e-04200644d89d3c16406d77cb08e1aa00d7df6887a692c337
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ZNF536 NHS SLC40A1 CDH7

1.95e-04200644d459e51507bf26865e6e7e04411379ec82a3edf8
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-MAIT|ICU-NoSEP / Disease, condition lineage and cell class

AFAP1L2 EFCAB13 DCBLD1 CTNS

1.95e-042006444f03b5f4110ed1637ffe17cb6ff309265a3af9a8
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)|Striatum / BrainAtlas - Mouse McCarroll V32

ZAN IL18RAP CHRNE

2.01e-0479643239d34f40c3a96186231f3aabd41c4988af3f372
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Striatum / BrainAtlas - Mouse McCarroll V32

ZAN IL18RAP CHRNE

2.01e-0479643a60fcbb278ba629af922c53faf58e4d96c537b15
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

BDP1 RESF1 ATF7IP AHNAK

4.13e-0549434GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Diseaseinterleukin 18 receptor accessory protein measurement

IL18RAP TNXB

1.60e-049632EFO_0008179
DiseaseSeasonal Affective Disorder

SLC6A4 CRY1

5.28e-0416632C0085159
Diseasecongenital myasthenic syndrome (implicated_via_orthology)

CHRNB3 CHRNE

5.28e-0416632DOID:3635 (implicated_via_orthology)
Diseasedepressive disorder (is_implicated_in)

SLC6A4 CHRNB3

5.98e-0417632DOID:1596 (is_implicated_in)
DiseaseFEV/FEC ratio

DCBLD1 NASP SRGAP2 LRRC37B TNXB SH3D21 SDC4 TOP2B ADD3

1.14e-031228639EFO_0004713
Diseasemalaria

ZNF536 IL20RA CRBN

1.37e-03102633EFO_0001068
Diseasebone fracture

ARFGAP2 AHNAK SLC40A1

1.79e-03112633EFO_0003931

Protein segments in the cluster

PeptideGeneStartEntry
TSEEVRTLEELLKPP

TADA3

166

O75528
VIEEIIPSSSKVIPL

CHRNB3

281

Q05901
PREKTPEVTDATEEI

BDP1

966

A6H8Y1
PREKTPEVIDATEEI

BDP1

1021

A6H8Y1
PKILESSVDPIDEIS

ALPK2

1396

Q86TB3
TIKSPEKIEEVLSPE

ADD3

661

Q9UEY8
KIEPRELDPILTEVT

COG4

346

Q9H9E3
LEPEDPSLRITTVKI

AFAP1L2

601

Q8N4X5
IPDTEDEISPDKVIL

CRBN

426

Q96SW2
IKSPSLDVTVPEAEL

AHNAK

4991

Q09666
TPIIRSKIEEPSVVE

ATF2

116

P15336
ETLPELPSVTREKLV

GATB

371

O75879
EKEPEVTISSIRPIS

ARFGAP2

386

Q8N6H7
LTKEEPVPLETQVVE

BCL7B

161

Q9BQE9
SLEKIVPIIAVPSSE

CASP8AP2

1021

Q9UKL3
SEPLSTIKNEETIEP

CCDC14

706

Q49A88
PVREPEDTVTISLKV

CHRNE

41

Q04844
PKVPSISTETEEEEV

RBM27

1016

Q9P2N5
MESETEPEPVTLLVK

HERPUD1

1

Q15011
EELPEITEVPESIKR

CDRT15

131

Q96T59
PVEDTLEVELGKPLT

IL18RAP

256

O95256
VTPPELEETIRDEKI

LRIF1

731

Q5T3J3
LELSITTEPTTEVKP

LRRC37B

421

Q96QE4
ALPVITKVETLSPES

FOXC2

221

Q99958
TDDPPDLTVIDKLVV

NOP14

486

P78316
ESDSEKVQPLPISTI

MSL2

346

Q9HCI7
PIEPQTSIERLTETK

NASP

391

P49321
ESLSRTIPPDKTVIE

IL20RA

386

Q9UHF4
KTEEDVPETSPIINT

PTPRQ

1186

Q9UMZ3
SPEVIVTSLSLPVKE

PCDHA10

346

Q9Y5I2
PRSITPLESEIIIDD

GPCPD1

96

Q9NPB8
LEEPEKEEIETSLPI

CMYA5

501

Q8N3K9
KEEIETSLPIAITPE

CMYA5

506

Q8N3K9
ITEPSKIAPSDLLVE

CMYA5

1806

Q8N3K9
TKESEKPESIILPVE

CMYA5

2401

Q8N3K9
KKTPETIPLTEDVLI

CENPK

76

Q9BS16
EPLEIPVETITSEVI

CRY1

161

Q16526
IEKEISPEIRSLSPE

EFCAB13

46

Q8IY85
AEPILEVEVTLSKPV

EIF4G1

321

Q04637
ETDEIIPILEKLAPS

ATF7IP

431

Q6VMQ6
TVETTDPEKEVEPAL

GDI1

356

P31150
ESSVSLTVPPVVKLE

CTNS

21

O60931
TTTVKIIVEDVDEPP

CDH7

361

Q9ULB5
KEDETITRPIPSEET

DCBLD1

436

Q8N8Z6
VIPKRISPVEESEDV

SDC4

111

P31431
LESVLESTLEPVIEP

STAT2

751

P52630
SIIPEETLTVDKPST

SH3D21

316

A4FU49
DEAPTLEKVLTPELS

SH3D21

361

A4FU49
KSESDLEETEPVVIP

TOP2B

1341

Q02880
VTKDQVRTETEPIPE

NHS

1246

Q6T4R5
EEVEAVTIVETPPLV

RPL3L

71

Q92901
LAEPQKEEPITEVVS

RESF1

1131

Q9HCM1
KVSDIEPTIPVTELD

PITRM1

561

Q5JRX3
DHVSIVEPKDEILPT

RPS3

206

P23396
ELISTPSVEDKSEEP

SECISBP2

586

Q96T21
ESITPTKIPEITTEI

SLC40A1

416

Q9NP59
KVLPLTTPLVDGEDE

TSC22D1

956

Q15714
IPLPEIKTKIEEATV

CLRN2

211

A0PK11
SEPEETPIKTEADVL

NUFIP1

376

Q9UHK0
IEVISEPPEEKVTAR

SRGAP2

801

O75044
DVVLDTLEPLKTSPV

SRGAP2

971

O75044
PIKPRLEELTVTDAT

TNXB

2301

P22105
EEVEPSLLEILPKSS

MPL

561

P40238
SEEDVPILIPETTSK

ZNF536

1141

O15090
EPLIATSEELKATPE

TTC16

546

Q8NEE8
ERIIKSITPETPTEI

SLC6A4

606

P31645
SEELETPIKDSHLIP

TOPBP1

1216

Q92547
EETIISTEKPTISPE

ZAN

701

Q9Y493
LEITSPEVPDLTIID

MX2

211

P20592
VTAEKLPTPQEETSL

NACAD

541

O15069