Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal protein binding	LGMN KIF6 SHROOM3 IQGAP2 MAP2 DISC1 SPTAN1 SPTBN1 SPTBN2 EML6 OBSCN GBP2 NEB MPRIP CEP350 NF1 ABITRAM MACF1 DAAM2 MYH15 AATF CEP295 KIF5A GOLGA8A WASF1	9.30e-06	1099	173	25	GO:0008092
GeneOntologyMolecularFunction	ATP-dependent activity	KIF6 ERCC6 ABCB5 DNAH2 DHX57 MCM5 DDX56 CHD7 ABCA7 NLRP3 DNAH1 MLH3 IQCA1 ACSBG1 MACF1 MYH15 KIF5A	2.56e-05	614	173	17	GO:0140657
GeneOntologyMolecularFunction	actin filament binding	SHROOM3 IQGAP2 SPTAN1 SPTBN1 SPTBN2 NEB MPRIP ABITRAM MACF1 MYH15	2.99e-05	227	173	10	GO:0051015
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF6 ERCC6 ABCB5 DNAH2 DHX57 MCM5 DDX56 CHD7 ABCA7 NLRP3 MLH3 IQCA1 MACF1 KIF5A	3.16e-05	441	173	14	GO:0016887
GeneOntologyMolecularFunction	methionine adenosyltransferase activity	MAT1A MAT2A	7.46e-05	2	173	2	GO:0004478
GeneOntologyMolecularFunction	actin binding	SHROOM3 IQGAP2 MAP2 SPTAN1 SPTBN1 SPTBN2 GBP2 NEB MPRIP ABITRAM MACF1 DAAM2 MYH15 WASF1	7.69e-05	479	173	14	GO:0003779
GeneOntologyMolecularFunction	testosterone 16-alpha-hydroxylase activity	CYP3A4 CYP3A43	4.43e-04	4	173	2	GO:0008390
GeneOntologyMolecularFunction	endopeptidase activator activity	LGMN NLRP3 PSME3	5.59e-04	19	173	3	GO:0061133
GeneOntologyMolecularFunction	testosterone 6-beta-hydroxylase activity	CYP3A4 CYP3A43	7.34e-04	5	173	2	GO:0050649
GeneOntologyMolecularFunction	vitamin D 23-hydroxylase activity	CYP3A4 CYP3A43	7.34e-04	5	173	2	GO:0062179
GeneOntologyMolecularFunction	1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity	CYP3A4 CYP3A43	7.34e-04	5	173	2	GO:0062181
GeneOntologyMolecularFunction	calmodulin binding	IQGAP2 MAP2 SPTAN1 SPTBN1 OBSCN MYH15 TRPV6 FKBP8	9.11e-04	230	173	8	GO:0005516
GeneOntologyMolecularFunction	vitamin D3 25-hydroxylase activity	CYP3A4 CYP3A43	1.09e-03	6	173	2	GO:0030343
GeneOntologyMolecularFunction	MAP kinase kinase kinase kinase activity	MAP4K3 MAP4K5	1.09e-03	6	173	2	GO:0008349
GeneOntologyMolecularFunction	vitamin D 24-hydroxylase activity	CYP3A4 CYP3A43	1.09e-03	6	173	2	GO:0070576
GeneOntologyMolecularFunction	microtubule binding	KIF6 MAP2 EML6 CEP350 NF1 MACF1 CEP295 KIF5A GOLGA8A	1.50e-03	308	173	9	GO:0008017
GeneOntologyMolecularFunction	vitamin D 25-hydroxylase activity	CYP3A4 CYP3A43	1.52e-03	7	173	2	GO:0070643
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor	CYP3A4 CYP3A43	2.02e-03	8	173	2	GO:0033695
GeneOntologyMolecularFunction	caffeine oxidase activity	CYP3A4 CYP3A43	2.02e-03	8	173	2	GO:0034875
GeneOntologyMolecularFunction	estrogen 2-hydroxylase activity	CYP3A4 CYP3A43	2.02e-03	8	173	2	GO:0101021
GeneOntologyCellularComponent	spectrin	SPTAN1 SPTBN1 SPTBN2	4.75e-05	9	176	3	GO:0008091
GeneOntologyCellularComponent	methionine adenosyltransferase complex	MAT1A MAT2A	2.10e-04	3	176	2	GO:0048269
GeneOntologyCellularComponent	cell cortex	FNBP1 SHROOM3 IQGAP2 GLRX3 SPTAN1 SPTBN1 SPTBN2 FRYL TRIP10 MACF1 PHLDB2	3.20e-04	371	176	11	GO:0005938
Domain	SH3	FNBP1 CACNB1 CACNB4 SPTAN1 OBSCN SAMSN1 NEB TRIP10 MACF1 UBASH3B	3.10e-05	216	171	10	PS50002
Domain	SH3_domain	FNBP1 CACNB1 CACNB4 SPTAN1 OBSCN SAMSN1 NEB TRIP10 MACF1 UBASH3B	3.63e-05	220	171	10	IPR001452
Domain	Spectrin	SPTAN1 SPTBN1 SPTBN2 MACF1	5.24e-05	23	171	4	PF00435
Domain	CCDC74	CCDC74B CCDC74A	8.33e-05	2	171	2	IPR033226
Domain	S-AdoMet_synt_N	MAT1A MAT2A	8.33e-05	2	171	2	PF00438
Domain	DUF4061	CCDC28B CCDC28A	8.33e-05	2	171	2	PF13270
Domain	CCDC74_C	CCDC74B CCDC74A	8.33e-05	2	171	2	IPR029422
Domain	DUF4061	CCDC28B CCDC28A	8.33e-05	2	171	2	IPR025271
Domain	S-AdoMet_synthetase	MAT1A MAT2A	8.33e-05	2	171	2	IPR002133
Domain	CCDC74_C	CCDC74B CCDC74A	8.33e-05	2	171	2	PF14917
Domain	S-AdoMet_synt_M	MAT1A MAT2A	8.33e-05	2	171	2	PF02772
Domain	S-AdoMet_synt_C	MAT1A MAT2A	8.33e-05	2	171	2	PF02773
Domain	ADOMET_SYNTHASE_CS	MAT1A MAT2A	8.33e-05	2	171	2	IPR022631
Domain	S-AdoMet_synt_C	MAT1A MAT2A	8.33e-05	2	171	2	IPR022630
Domain	S-AdoMet_synthetase_sfam	MAT1A MAT2A	8.33e-05	2	171	2	IPR022636
Domain	S-AdoMet_synt_central	MAT1A MAT2A	8.33e-05	2	171	2	IPR022629
Domain	S-AdoMet_synt_N	MAT1A MAT2A	8.33e-05	2	171	2	IPR022628
Domain	ADOMET_SYNTHASE_1	MAT1A MAT2A	8.33e-05	2	171	2	PS00376
Domain	ADOMET_SYNTHASE_2	MAT1A MAT2A	8.33e-05	2	171	2	PS00377
Domain	Spectrin_repeat	SPTAN1 SPTBN1 SPTBN2 MACF1	1.35e-04	29	171	4	IPR002017
Domain	SH3	FNBP1 CACNB1 CACNB4 SPTAN1 OBSCN SAMSN1 NEB TRIP10 UBASH3B	1.73e-04	216	171	9	SM00326
Domain	SPEC	SPTAN1 SPTBN1 SPTBN2 MACF1	2.00e-04	32	171	4	SM00150
Domain	Spectrin/alpha-actinin	SPTAN1 SPTBN1 SPTBN2 MACF1	2.00e-04	32	171	4	IPR018159
Domain	RHIM	RIPK3 RIPK1	2.49e-04	3	171	2	PF12721
Domain	RHIM_dom	RIPK3 RIPK1	2.49e-04	3	171	2	IPR025735
Domain	VDCC_L_bsu	CACNB1 CACNB4	4.94e-04	4	171	2	IPR000584
Domain	Spectrin_bsu	SPTBN1 SPTBN2	4.94e-04	4	171	2	IPR016343
Domain	MAPKKKK	MAP4K3 MAP4K5	4.94e-04	4	171	2	IPR021160
Domain	VGCC_beta4Aa_N	CACNB1 CACNB4	4.94e-04	4	171	2	PF12052
Domain	SH3_1	FNBP1 CACNB1 CACNB4 SPTAN1 NEB TRIP10 UBASH3B	7.96e-04	164	171	7	PF00018
Domain	Cyt_P450_E_grp-II	CYP3A4 CYP3A43	8.18e-04	5	171	2	IPR002402
Domain	TPR_REGION	DNAH2 TTC27 SRP72 ZFC3H1 TMTC3 VPS13A FKBP8	8.25e-04	165	171	7	PS50293
Domain	TPR	DNAH2 TTC27 SRP72 ZFC3H1 TMTC3 VPS13A FKBP8	8.25e-04	165	171	7	PS50005
Domain	Ank_2	ANKRD37 ANKRD20A2P ANKRD20A3P SNCAIP ANKRD20A4P ANKDD1B TRPV6 ANKRD20A1	8.37e-04	215	171	8	PF12796
Domain	ACTININ_2	SPTBN1 SPTBN2 MACF1	1.17e-03	23	171	3	PS00020
Domain	ACTININ_1	SPTBN1 SPTBN2 MACF1	1.17e-03	23	171	3	PS00019
Domain	Actinin_actin-bd_CS	SPTBN1 SPTBN2 MACF1	1.17e-03	23	171	3	IPR001589
Domain	-	TDRD15 TDRD6	1.22e-03	6	171	2	2.40.50.90
Domain	Cyt_P450_E_CYP3A	CYP3A4 CYP3A43	1.22e-03	6	171	2	IPR008072
Domain	Staphylococal_nuclease_OB-fold	TDRD15 TDRD6	1.22e-03	6	171	2	IPR016071
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	COL5A1 CACNB1 CACNB4 SPTAN1 SPTBN1 SPTBN2	2.12e-05	63	127	6	M11187
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTAN1 SPTBN1 SPTBN2	8.18e-05	10	127	3	MM15112
Pathway	REACTOME_TRP_CHANNELS	TRPM6 RIPK3 RIPK1 TRPV6	1.09e-04	28	127	4	MM14943
Pathway	REACTOME_TRP_CHANNELS	TRPM6 RIPK3 RIPK1 TRPV6	1.09e-04	28	127	4	M27241
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN11A SPTAN1 SPTBN1 SPTBN2	1.64e-04	31	127	4	M877
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	COL5A1 SPTAN1 SPTBN1 SPTBN2 BAZ1B SRP72 DHX57 MCM5 DDX56 FRYL CHD7 UBE2O NF1 GEMIN4 MACF1 AATF PCM1 TP53BP1 SON	2.53e-09	653	185	19	22586326
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNB1 CACNB4 SHROOM3 IQGAP2 SPTAN1 SPTBN1 SPTBN2 HECTD4 CHD7 MPRIP UBE2O NF1 TRIM67 MACF1 KIF5A UBASH3B GOLGA8A WASF1 PCM1 TP53BP1 PHLDB2	5.30e-08	963	185	21	28671696
Pubmed	Inhibition of RIPK1/RIPK3 ameliorates osteoclastogenesis through regulating NLRP3-dependent NF-κB and MAPKs signaling pathways.	RIPK3 RIPK1 NLRP3	1.48e-07	3	185	3	32321638
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SCN11A IQGAP2 PCDHGB3 ABCB5 SPTAN1 SPTBN1 SPTBN2 EML6 DNAH2 SRP72 DHX57 MCM5 ZFC3H1 NEB OGDH RINT1 TRIM67 VPS13A MACF1 MYH15 AATF CEP295 KIF5A MAPK6 PCDHGC3	2.17e-07	1442	185	25	35575683
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ERCC6 MAP4K3 MAT2A SPTAN1 SPTBN1 TTC27 BAZ1B DHX57 MCM5 DDX56 CHD7 POLR3A MPRIP RLF NF1 CLIC1 MAP4K5 GEMIN4 MACF1 AATF PSME3 TP53BP1 PHLDB2 SON	2.57e-07	1353	185	24	29467282
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	BRPF3 ERCC6 TRIM4 ZNF460 TTC27 BAZ1B DDX56 ABCA7 MLH3 COQ8A CCNB3 ZFP91 MACF1 MAIP1 CEP295 LRRC8B FKBP8 UNC80 PCM1 PHLDB2 SON	5.99e-07	1116	185	21	31753913
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 SHROOM3 MAP2 SEC24A SPTAN1 SPTBN1 FRYL MAP3K6 RSRC1 MPRIP CEP350 NF1 SLF2 TET1 RNF10 MACF1 PCM1 PHLDB2	9.19e-07	861	185	18	36931259
Pubmed	Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.	RIPK3 RIPK1 ZFP91	1.47e-06	5	185	3	34942311
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TRPM6 LARGE2 FNBP1 LGMN IQGAP2 MAP4K3 SPTBN1 OBSCN BAZ1B FRYL CHD7 MTMR6 COQ8A TET1 RBPJ MACF1 AATF CEP295 ESPL1 TP53BP1	1.53e-06	1084	185	20	11544199
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	DISC1 SPTAN1 SPTBN1 FRYL MACF1 CEP295 PSME3 KIF5A	1.60e-06	151	185	8	17043677
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	PALD1 COL5A1 IQGAP2 GLRX3 SPTAN1 SPTBN1 SPTBN2 TTC27 SRP72 DHX57 MCM5 DDX56 OGDH POLR3A DNAAF5 RINT1 COQ8A CLIC1 GEMIN4 MAIP1 PSME3 FKBP8 PCM1	2.76e-06	1440	185	23	30833792
Pubmed	ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors.	SPTAN1 SPTBN1 SPTBN2	2.93e-06	6	185	3	37069398
Pubmed	RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.	RIPK3 RIPK1 NLRP3	2.93e-06	6	185	3	23708968
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF3 NBPF8 NBPF12 NBPF1	4.32e-06	21	185	4	16079250
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	FNBP1 CACNB1 CACNB4 MAP2 SPTAN1 SPTBN1 MPRIP PTPRZ1 MACF1	4.49e-06	231	185	9	16452087
Pubmed	RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway.	RIPK3 RIPK1 NLRP3	8.13e-06	8	185	3	25326752
Pubmed	Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease.	RIPK3 RIPK1 NLRP3	8.13e-06	8	185	3	31869420
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A3P ANKRD20A4P ANKRD20A1	8.13e-06	8	185	3	12634303
Pubmed	cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation.	RIPK3 RIPK1 NLRP3	8.13e-06	8	185	3	32193329
Pubmed	Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.	RIPK3 RIPK1 NLRP3	8.13e-06	8	185	3	26104484
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	FNBP1 DNAH2 CHD7 NEB CEP350 NF1 TMTC3 COQ8A VPS13A AATF MAIP1 CEP295 WASF1 TARBP1	9.13e-06	638	185	14	31182584
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	MAP2 ZNF460 ABCB5 PIDD1 BAZ1B NEB MTMR6 MACF1 ESPL1 TANGO6	9.75e-06	322	185	10	26514267
Pubmed	Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.	RIPK3 RIPK1 NLRP3	1.21e-05	9	185	3	24799678
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	CCDC28B SPTAN1 SPTBN1 EML6 BAZ1B MPRIP EYS MACF1 PCM1 SON	1.27e-05	332	185	10	37433992
Pubmed	Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.	LAMC3 BGN DAAM2 KAZN	1.44e-05	28	185	4	33953184
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	RALGAPA1 TACO1 SHROOM3 MAP2 SPTAN1 SPTBN1 SPTBN2 BAZ1B ZFC3H1 OGDH MPRIP RINT1 UBE2O TMTC3 MAP4K5 VPS13A MACF1 MRPL40 FKBP8 ESPL1 PCM1 TP53BP1	1.52e-05	1487	185	22	33957083
Pubmed	TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation.	RIPK3 RIPK1 NLRP3	1.73e-05	10	185	3	29500178
Pubmed	Cell organization, growth, and neural and cardiac development require αII-spectrin.	SPTAN1 SPTBN1 SPTBN2	1.73e-05	10	185	3	22159418
Pubmed	Evolutionary history and genome organization of DUF1220 protein domains.	NBPF8 NBPF12 NBPF1	1.73e-05	10	185	3	22973535
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	MAT2A SPTAN1 SPTBN1 FRYL UBE2O CLIC1 GEMIN4	2.15e-05	156	185	7	22952844
Pubmed	Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.	SPTAN1 SPTBN1 SPTBN2	2.37e-05	11	185	3	17607528
Pubmed	RIP1K and RIP3K provoked by shikonin induce cell cycle arrest in the triple negative breast cancer cell line, MDA-MB-468: necroptosis as a desperate programmed suicide pathway.	RIPK3 RIPK1	2.81e-05	2	185	2	26496737
Pubmed	The Bcr-Abl inhibitor GNF-7 inhibits necroptosis and ameliorates acute kidney injury by targeting RIPK1 and RIPK3 kinases.	RIPK3 RIPK1	2.81e-05	2	185	2	32247850
Pubmed	RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome.	RIPK3 RIPK1	2.81e-05	2	185	2	28176780
Pubmed	The frameshift polymorphism CYP3A43_74_delA is associated with poor differentiation of breast tumors.	CYP3A4 CYP3A43	2.81e-05	2	185	2	20715157
Pubmed	Positive and negative phosphorylation regulates RIP1- and RIP3-induced programmed necrosis.	RIPK3 RIPK1	2.81e-05	2	185	2	24059293
Pubmed	The Role of RIPK1/3 in Adult Onset Still's Disease Patients With Liver Damage: A Preliminary Study.	RIPK3 RIPK1	2.81e-05	2	185	2	33329521
Pubmed	Mosaic composition of RIP1-RIP3 signalling hub and its role in regulating cell death.	RIPK3 RIPK1	2.81e-05	2	185	2	35256774
Pubmed	Distinctive roles of receptor-interacting protein kinases 1 and 3 in caspase-independent cell death of L929.	RIPK3 RIPK1	2.81e-05	2	185	2	23584955
Pubmed	Role of transcriptional and posttranscriptional regulation of methionine adenosyltransferases in liver cancer progression.	MAT1A MAT2A	2.81e-05	2	185	2	22318685
Pubmed	Necroptosis in cardiovascular disease - a new therapeutic target.	RIPK3 RIPK1	2.81e-05	2	185	2	29524460
Pubmed	The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis.	RIPK3 RIPK1	2.81e-05	2	185	2	24314238
Pubmed	The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice.	RIPK3 RIPK1	2.81e-05	2	185	2	25674205
Pubmed	RIP1 kinase mediates angiogenesis by modulating macrophages in experimental neovascularization.	RIPK3 RIPK1	2.81e-05	2	185	2	31685620
Pubmed	Investigation on the expression regulation of RIPK1/RIPK3 in the retinal ganglion cells (RGCs) cultured in high glucose.	RIPK3 RIPK1	2.81e-05	2	185	2	34281454
Pubmed	Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis.	FNBP1 TRIP10	2.81e-05	2	185	2	17512409
Pubmed	Identification of a mouse brain beta-spectrin cDNA and distribution of its mRNA in adult tissues.	SPTAN1 SPTBN1	2.81e-05	2	185	2	1742606
Pubmed	A novel mechanism of the M1-M2 methionine adenosyltransferase switch-mediated hepatocellular carcinoma metastasis.	MAT1A MAT2A	2.81e-05	2	185	2	29749642
Pubmed	K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo.	RIPK3 RIPK1	2.81e-05	2	185	2	27258786
Pubmed	The diverse role of RIP kinases in necroptosis and inflammation.	RIPK3 RIPK1	2.81e-05	2	185	2	26086143
Pubmed	Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo.	RIPK3 RIPK1	2.81e-05	2	185	2	25015821
Pubmed	Programmed necrosis and necroptosis signalling.	RIPK3 RIPK1	2.81e-05	2	185	2	25327580
Pubmed	The design of coiled-coil structures and assemblies.	CCDC168 CCDC74A	2.81e-05	2	185	2	15837514
Pubmed	RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury.	RIPK3 RIPK1	2.81e-05	2	185	2	34404478
Pubmed	Sensitizing acute myeloid leukemia cells to induced differentiation by inhibiting the RIP1/RIP3 pathway.	RIPK3 RIPK1	2.81e-05	2	185	2	27748372
Pubmed	CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.	CHD7 TP53BP1	2.81e-05	2	185	2	33188175
Pubmed	Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury.	RIPK3 RIPK1	2.81e-05	2	185	2	25950489
Pubmed	The DISC1 Ser704Cys substitution affects centrosomal localization of its binding partner PCM1 in glia in human brain.	DISC1 PCM1	2.81e-05	2	185	2	20360304
Pubmed	RIP3 dependent NLRP3 inflammasome activation is implicated in acute lung injury in mice.	RIPK3 NLRP3	2.81e-05	2	185	2	30126430
Pubmed	Alterations of Methionine Metabolism as Potential Targets for the Prevention and Therapy of Hepatocellular Carcinoma.	MAT1A MAT2A	2.81e-05	2	185	2	31234428
Pubmed	Spectrin-actin interaction is required for neurite extension in NB 2a/dl neuroblastoma cells.	SPTAN1 SPTBN1	2.81e-05	2	185	2	8776664
Pubmed	Histological expression of methionine adenosyl transferase (MAT) 2A as a post-surgical prognostic surrogate in patients with hepatocellular carcinoma.	MAT1A MAT2A	2.81e-05	2	185	2	29448301
Pubmed	Targeting RIP Kinases in Chronic Inflammatory Disease.	RIPK3 RIPK1	2.81e-05	2	185	2	33924766
Pubmed	Enhancement of CYP3A4 activity in Hep G2 cells by lentiviral transfection of hepatocyte nuclear factor-1 alpha.	HNF1A CYP3A4	2.81e-05	2	185	2	24733486
Pubmed	Caspase-3/7-mediated Cleavage of β2-spectrin is Required for Acetaminophen-induced Liver Damage.	SPTBN1 SPTBN2	2.81e-05	2	185	2	26884715
Pubmed	Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis.	RIPK3 RIPK1	2.81e-05	2	185	2	21098270
Pubmed	CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment.	CCDC74B CCDC74A	2.81e-05	2	185	2	31521166
Pubmed	Receptor-interacting protein 1 and 3 kinase activity are required for high-fat diet induced liver injury in mice.	RIPK3 RIPK1	2.81e-05	2	185	2	38161978
Pubmed	Evaluation of RIP1K and RIP3K expressions in the malignant and benign breast tumors.	RIPK3 RIPK1	2.81e-05	2	185	2	26749282
Pubmed	Frequency and amplitude control of cortical oscillations by phosphoinositide waves.	FNBP1 TRIP10	2.81e-05	2	185	2	26751515
Pubmed	RIP3 S-nitrosylation contributes to cerebral ischemic neuronal injury.	RIPK3 RIPK1	2.81e-05	2	185	2	26319693
Pubmed	Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis.	RIPK3 RIPK1	2.81e-05	2	185	2	29686269
Pubmed	RIPK1 and RIPK3 regulate TNFα-induced β-cell death in concert with caspase activity.	RIPK3 RIPK1	2.81e-05	2	185	2	36030035
Pubmed	Molecular Pathways: The Necrosome-A Target for Cancer Therapy.	RIPK3 RIPK1	2.81e-05	2	185	2	27932417
Pubmed	The N-end rule ubiquitin ligase UBR2 mediates NLRP1B inflammasome activation by anthrax lethal toxin.	UBR2 UBE2O	2.81e-05	2	185	2	31268597
Pubmed	Expression of Protein Kinases RIPK-1 and RIPK-3 in Mouse and Human Hair Follicle.	RIPK3 RIPK1	2.81e-05	2	185	2	33119828
Pubmed	Cell Death and Inflammation - A Vital but Dangerous Liaison.	RIPK3 RIPK1	2.81e-05	2	185	2	31003931
Pubmed	Astrocyte-Derived TNF-α-Activated Platelets Promote Cerebral Ischemia/Reperfusion Injury by Regulating the RIP1/RIP3/AKT Signaling Pathway.	RIPK3 RIPK1	2.81e-05	2	185	2	35781632
Pubmed	RIPK3 and RIPK1 gene expression in pterygium: unveiling molecular insights into pathogenesis.	RIPK3 RIPK1	2.81e-05	2	185	2	38630344
Pubmed	DISC-1 Leu607Phe alleles differentially affect centrosomal PCM1 localization and neurotransmitter release.	DISC1 PCM1	2.81e-05	2	185	2	19455170
Pubmed	S-adenosyl-L-methionine modifies antioxidant-enzymes, glutathione-biosynthesis and methionine adenosyltransferases-1/2 in hepatitis C virus-expressing cells.	MAT1A MAT2A	2.81e-05	2	185	2	27076759
Pubmed	Characterization of a new beta-spectrin gene which is predominantly expressed in brain.	SPTAN1 SPTBN2	2.81e-05	2	185	2	9675416
Pubmed	Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3.	RIPK3 RIPK1	2.81e-05	2	185	2	11734559
Pubmed	Altered expression of proteoglycan, collagen and growth factor genes in a TGF-β1 stimulated genetic risk model for musculoskeletal soft tissue injuries.	COL5A1 BGN	2.81e-05	2	185	2	32061523
Pubmed	Functional characterization of the human biglycan 5'-flanking DNA and binding of the transcription factor c-Krox.	ZBTB7B BGN	2.81e-05	2	185	2	9421237
Pubmed	Structures of the murine genes for the beta1- and beta4-subunits of the voltage-dependent calcium channel.	CACNB1 CACNB4	2.81e-05	2	185	2	14500989
Pubmed	Role of receptor-interacting protein 1/receptor-interacting protein 3 in inflammation and necrosis following chronic constriction injury of the sciatic nerve.	RIPK3 RIPK1	2.81e-05	2	185	2	30192300
Pubmed	Activation of MAT2A-RIP1 signaling axis reprograms monocytes in gastric cancer.	RIPK1 MAT2A	2.81e-05	2	185	2	33593829
Pubmed	RIP3, a novel apoptosis-inducing kinase.	RIPK3 RIPK1	2.81e-05	2	185	2	10358032
Pubmed	Receptor-interacting protein kinases modulate noise-induced sensory hair cell death.	RIPK3 RIPK1	2.81e-05	2	185	2	24874734
Pubmed	Herpes simplex virus suppresses necroptosis in human cells.	RIPK3 RIPK1	2.81e-05	2	185	2	25674983
Pubmed	RIP1/RIP3 binding to HSV-1 ICP6 initiates necroptosis to restrict virus propagation in mice.	RIPK3 RIPK1	2.81e-05	2	185	2	25674982
Pubmed	Virus inhibition of RIP3-dependent necrosis.	RIPK3 RIPK1	2.81e-05	2	185	2	20413098
Pubmed	Cloning of a portion of the chromosomal gene and cDNA for human beta-fodrin, the nonerythroid form of beta-spectrin.	SPTAN1 SPTBN1	2.81e-05	2	185	2	8406479
Pubmed	Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity.	RIPK3 RIPK1	2.81e-05	2	185	2	31227597
Pubmed	Curcumin alleviates experimental colitis in mice by suppressing necroptosis of intestinal epithelial cells.	RIPK3 RIPK1	2.81e-05	2	185	2	37089942
Pubmed	Shikonin induces glioma cell necroptosis in vitro by ROS overproduction and promoting RIP1/RIP3 necrosome formation.	RIPK3 RIPK1	2.81e-05	2	185	2	28816233
Pubmed	Cis-acting regulatory elements regulating CYP3A4 transcription in human liver.	CYP3A4 CYP3A43	2.81e-05	2	185	2	32301865
Pubmed	Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis.	RIPK3 RIPK1 NLRP3	3.14e-05	12	185	3	30451870
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	MMS22L BRPF3 CYP3A4 CYP3A43 SEC24A SPTBN1 BAZ1B LAMC3 FRYL CHD7 OGDH NF1 KLHL30 TET1 VPS13A RNF10 DAAM2 KAZN FHIP1A	3.85e-05	1242	185	19	30973865
Interaction	YWHAG interactions	RALGAPA1 HNF1A SHROOM3 MAP2 MAP4K3 DISC1 SEC24A SPTAN1 SPTBN1 HECTD4 MCM5 FRYL SAMSN1 MAP3K6 RSRC1 MPRIP CEP350 CFD NF1 TRIM67 MAP4K5 TET1 MACF1 MTBP KIF5A WASF1 PCM1 PHLDB2 SON	2.54e-06	1248	182	29	int:YWHAG
Interaction	NTAN1 interactions	UBR2 RIPK1 ATE1 MAP4K5	4.32e-06	13	182	4	int:NTAN1
Interaction	ANK1 interactions	NBPF3 SPTAN1 SPTBN1 OBSCN TRIM67 FKBP8	1.12e-05	56	182	6	int:ANK1
Interaction	ANKRD20A4P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	1.42e-05	6	182	3	int:ANKRD20A4P
Interaction	YWHAB interactions	RALGAPA1 HNF1A SHROOM3 MAP2 SEC24A SPTAN1 SPTBN1 HECTD4 FRYL SAMSN1 NEB SHOC2 MPRIP CEP350 CFD NF1 TRIM67 MACF1 MTBP KIF5A WASF1 PCM1 PHLDB2 SON	1.52e-05	1014	182	24	int:YWHAB
Interaction	YWHAH interactions	RALGAPA1 LGMN SHROOM3 MAP2 SEC24A SPTAN1 SPTBN1 HECTD4 FRYL SAMSN1 MAP3K6 MPRIP CEP350 SNCAIP NF1 TRIM67 SLF2 TET1 RNF10 MACF1 MTBP KIF5A WASF1 PCM1 PHLDB2	2.03e-05	1102	182	25	int:YWHAH
Interaction	ANKRD20A2P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	2.47e-05	7	182	3	int:ANKRD20A2P
Interaction	KALRN interactions	DISC1 SPTAN1 SPTBN1 SPTBN2 SNCAIP TRIM67 MACF1	2.64e-05	96	182	7	int:KALRN
Interaction	MRPS25 interactions	TACO1 ERCC6 ZNF460 MAP4K3 DDX56 CEP76 ZFC3H1 ZBTB7B CFD TRIM67 AATF	3.49e-05	269	182	11	int:MRPS25
Interaction	SIRT7 interactions	COL5A1 SPTAN1 SPTBN1 SPTBN2 BAZ1B SRP72 DHX57 MCM5 DDX56 FRYL CHD7 UBE2O NF1 GEMIN4 MACF1 AATF PCM1 TP53BP1 SON	4.60e-05	744	182	19	int:SIRT7
Interaction	RTL1 interactions	MAP4K3 TRIM67 MAP4K5	5.85e-05	9	182	3	int:RTL1
GeneFamily	EF-hand domain containing\|Spectrins	SPTAN1 SPTBN1 SPTBN2	9.07e-06	7	117	3	1113
GeneFamily	Neuroblastoma breakpoint family	NBPF3 NBPF8 NBPF12 NBPF1	1.34e-05	23	117	4	662
GeneFamily	Ankyrin repeat domain containing	ANKRD37 ANKRD20A2P ANKRD20A3P SNCAIP ANKRD20A4P ANKDD1B TRPV6 ANKRD20A1	1.79e-04	242	117	8	403
GeneFamily	Mitogen-activated protein kinase kinase kinase kinases	MAP4K3 MAP4K5	4.10e-04	5	117	2	655
GeneFamily	Cytochrome P450 family 3	CYP3A4 CYP3A43	1.13e-03	8	117	2	1002
GeneFamily	Tudor domain containing	TDRD15 TDRD6 TP53BP1	1.75e-03	37	117	3	780
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	RALGAPA1 IQGAP2 BAZ1B FRYL CHD7 CEP350 NF1 MACF1 ESPL1 PCM1	5.89e-07	180	183	10	M8239
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	BHLHE41 PALD1 DISC1 LAMC3 NEB ZBTB7B BGN APOBEC3F PHLDB2	1.58e-07	200	184	9	25f4c051c2e869481f33c22ad54de97efac444ad
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial-Proteoglycan-expressing_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	BHLHE41 PALD1 DISC1 LAMC3 NEB ZBTB7B BGN APOBEC3F PHLDB2	1.58e-07	200	184	9	da45a85a4667965b24ba824af871157af5b4cd19
ToppCell	Control-B_naive-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	LARGE2 SPTBN1 NBPF1 COQ8A SLF2 MACF1 CEP295 GOLGA8A	5.85e-07	171	184	8	d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PALD1 OBSCN LAMC3 CHN1 ERVMER34-1 BGN DAAM2 PDZD2	1.19e-06	188	184	8	ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RALGAPA1 UBR2 FRYL ZFC3H1 VPS13A MACF1 GOLGA8A PCM1	1.83e-06	199	184	8	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	UBR2 FRYL ZFC3H1 CEP350 MACF1 GOLGA8A PCM1 SON	1.90e-06	200	184	8	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	facs-Heart-LV-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP76 SAMSN1 ZBTB7B IL18RAP UBE2O TLR5 PSME3	3.21e-06	151	184	7	5893a51585a65f1902cf85124a5ed9f02b4eb82a
ToppCell	facs-Heart-LV-18m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP76 SAMSN1 ZBTB7B IL18RAP UBE2O TLR5 PSME3	3.21e-06	151	184	7	771224e0d6fccfa4225b3adccd7bc22a89a40793
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	HECTD4 OBSCN SLC45A4 USP40 ANKDD1B NEK11 SON	5.99e-06	166	184	7	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	CACNB1 CCDC28B ZNF460 OBSCN PIDD1 POMZP3 MRPL40	6.47e-06	168	184	7	8697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCell	normal_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	OBSCN LAMC3 CHD7 CHN1 ZUP1 BGN KLHL30	7.00e-06	170	184	7	d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCell	Basal_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	TRPM6 LARGE2 COL5A1 ANKRD20A2P ANKRD20A3P ANKRD20A4P TDRD6	8.14e-06	174	184	7	a0060be3940043015dcc49a5157de5541aed24a1
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CACNB1 RIPK3 DISC1 SEC24A SRP72 POLR3A GOLGA8A	1.30e-05	187	184	7	c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CACNB1 RIPK3 DISC1 SEC24A SRP72 POLR3A GOLGA8A	1.39e-05	189	184	7	99b01893da9f9f7c9528afaffad178285211738b
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	RALGAPA1 SRP72 FRYL CEP350 ZFP91 LRRC8B SON	1.60e-05	193	184	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)\|Adult / Lineage, Cell type, age group and donor	FNBP1 LGMN IQGAP2 DISC1 SAMSN1 RBPJ UBASH3B	1.60e-05	193	184	7	31c0978ba78c9516d498aec0798902e57555e557
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRYL VPS13A MACF1 UNC80 PCM1 PHLDB2 SON	1.71e-05	195	184	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRYL VPS13A MACF1 UNC80 PCM1 PHLDB2 SON	1.71e-05	195	184	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FRYL ZFC3H1 SNCAIP VPS13A MACF1 GOLGA8A PCM1	1.82e-05	197	184	7	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Bronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PALD1 KIF6 OBSCN LAMC3 CHN1 BGN DAAM2	1.94e-05	199	184	7	929f809579368201331d9099d8904b6e3c41797b
ToppCell	Bronchial-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PALD1 KIF6 OBSCN LAMC3 CHN1 BGN DAAM2	1.94e-05	199	184	7	854628ce91068093c14bd4d45ba38c41469f3549
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuroepithelial\|5w / Sample Type, Dataset, Time_group, and Cell type.	PALD1 COL5A1 SAMSN1 BGN CCNB3 DAAM2 FHIP1A	2.01e-05	200	184	7	69707f9576d326a06faac49701ef5cd632e760f6
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuroepithelial-Proteoglycan-expressing_cell\|5w / Sample Type, Dataset, Time_group, and Cell type.	PALD1 COL5A1 SAMSN1 BGN CCNB3 DAAM2 FHIP1A	2.01e-05	200	184	7	f94381d0a3b5b81cdbb13b75fc0e4910cbd70382
ToppCell	Sepsis-URO-Myeloid-cDC1\|URO / Disease, condition lineage and cell class	PALD1 LGMN MCM5 RAVER2 CCDC74A MYH15 C19orf18	2.01e-05	200	184	7	c5ca81218be40b30e2f9252c1a004cb95d988447
ToppCell	droplet-Spleen-nan-18m-Hematologic-erythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRPF3 UBE2O RNF10 GEMIN4 PSME3	3.59e-05	90	184	5	85e5280b5b7d79fed3d356070843a26b50af944b
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|356C / Donor, Lineage, Cell class and subclass (all cells)	NBPF1 ANKRD20A4P TET1 MTBP TDRD6 NEK11	4.55e-05	155	184	6	e1a20e88b9c0eaf7ca7004acc0eda096d1588563
ToppCell	Control-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	LARGE2 NBPF1 COQ8A MACF1 CEP295 GOLGA8A	4.55e-05	155	184	6	0a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCell	IIF-Lymphocyte-T_NK-ILC\|IIF / Disease, Lineage and Cell Type	CACNB4 ERCC6 CYP3A43 NEB DNAH1 FHIP1A	5.24e-05	159	184	6	55e4f21548f480ca414c00cbff5ec3b13bafd271
ToppCell	CV-Mild-4\|Mild / Virus stimulation, Condition and Cluster	FNBP1 ANKRD37 NLRP3 NBPF1 UBE2O IQCA1	5.43e-05	160	184	6	2e24f8de5086b086863d3bf4d9afbd9bc93f4d5e
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ZNF460 DISC1 OBSCN ZFC3H1 IQCA1 MTBP	5.62e-05	161	184	6	58381131e651744b5141b202f9d6063f55432db5
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRPF3 HECTD4 UBE2O TRIM67 MAP4K5 RNF10	5.81e-05	162	184	6	08ee7ae56e4927874515c47adc86dd845bf29a26
ToppCell	facs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRPF3 CXorf38 EML6 LAMC3 UBE2O RAVER2	6.22e-05	164	184	6	1d0d88132baaa3154c3e6e4ef0aff795afab08a2
ToppCell	facs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRPF3 CXorf38 EML6 LAMC3 UBE2O RAVER2	6.22e-05	164	184	6	bd2e10b015d5e6a338675500ec5d81dc39583b3e
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL5A1 OBSCN BGN CFD PCDHGC3 PDZD2	6.22e-05	164	184	6	a764b79a127c8f360af0b79a1da64658badf0dfa
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TRIM4 BGN GEMIN4 C19orf18 GOLGA8A NEK11	7.59e-05	170	184	6	c1f7f1bb8865e954bb499963d82bb51923d5d8d6
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	SHROOM3 MAP2 SPTBN1 FHIP1A PHLDB2 PDZD2	7.59e-05	170	184	6	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	wk_20-22-Mesenchymal-Chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SCN11A MAP2 BGN IQCA1 PTPRZ1 DAAM2	7.84e-05	171	184	6	d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DISC1 EML6 HECTD4 PIDD1 MCM5 IL18RAP	8.10e-05	172	184	6	eba1568d4307e91c94fc616549057cbed8df5840
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RIPK1 IQGAP2 DISC1 IL18RAP MLH3 ACSBG1	8.36e-05	173	184	6	b6bb2a136a40f0946bbcde8d5972d3f059d080c7
ToppCell	COVID-19-kidney-PCT-S3-2\|kidney / Disease (COVID-19 only), tissue and cell type	TDRD15 CYP3A4 MAT1A CYP3A43 AMDHD1 ANKRD20A2P	8.63e-05	174	184	6	5aa2fb631505600f37d2b87b02def7be139dc262
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BHLHE41 PALD1 EML6 MCM5 SAMSN1 RINT1	9.19e-05	176	184	6	a9e77681bcd36c382d53eb6f771349d55f98d744
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP2 ZUP1 POLR3A OPTC NF1 TARBP1	9.48e-05	177	184	6	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	Endothelial-Endothelial-C\|Endothelial / shred on cell class and cell subclass (v4)	CCDC28B MAP4K3 DHX57 SLC45A4 MYH15 SON	9.48e-05	177	184	6	b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	OBSCN LAMC3 CHN1 BGN DAAM2 PDZD2	9.78e-05	178	184	6	185b44700f06ec58b3c09c80520502166c965fd6
ToppCell	droplet-Marrow-nan-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRPF3 HECTD4 UBE2O MAP4K5 RNF10 PSME3	9.78e-05	178	184	6	b4e15c176875cd226854a0019495309d02730c42
ToppCell	droplet-Marrow-nan-24m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRPF3 HECTD4 UBE2O MAP4K5 RNF10 PSME3	1.01e-04	179	184	6	7e6da098976c7801d31dcc0201f813d2bc8b07fc
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|356C / Donor, Lineage, Cell class and subclass (all cells)	CACNB1 RIPK3 DISC1 SRP72 POLR3A GOLGA8A	1.01e-04	179	184	6	f378307eb20f002450c748b7be2289d6db2fcbcb
ToppCell	Control-Myeloid-Dendritic_cells\|Control / group, cell type (main and fine annotations)	PALD1 IQGAP2 DISC1 SAMSN1 NLRP3 RBPJ	1.04e-04	180	184	6	25ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCell	facs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DISC1 MYOM3 DNAAF5 CFD GEMIN4 CAPN5	1.04e-04	180	184	6	7368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCell	droplet-Lung-LUNG-30m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAT1A ENO4 IQCA1 PTPRZ1 CCDC74A NEK11	1.14e-04	183	184	6	3991830726d05cf19606d540de04093985b7bdeb
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SCN11A KIF6 MAP2 IQCA1 MAP4K5 DAAM2	1.14e-04	183	184	6	1464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAT1A ENO4 IQCA1 PTPRZ1 CCDC74A NEK11	1.14e-04	183	184	6	cc844f54c7564bf432b179ca63bc7c4b9b8cfdd9
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN NEB DNAH1 MYH15 KIF5A UNC80	1.17e-04	184	184	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	PALD1 ANKRD20A2P ANKRD20A3P ANKRD20A4P FHIP1A ANKRD20A1	1.17e-04	184	184	6	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 BAZ1B CEP350 SLF2 MACF1 PCM1	1.17e-04	184	184	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN NEB DNAH1 MYH15 KIF5A UNC80	1.17e-04	184	184	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	Healthy/Control-B_memory\|World / Disease group and Cell class	BHLHE41 LARGE2 ZYG11A LGMN EML6 CHD7	1.17e-04	184	184	6	9e1879d86b535ede9b47deb0752e291f987a5d5e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN NEB DNAH1 MYH15 KIF5A UNC80	1.17e-04	184	184	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	SHROOM3 MAP2 SPTBN1 GOLGA8A PHLDB2 PDZD2	1.17e-04	184	184	6	561592edc3083fad41b91811151b442207c65dd9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 MAP2 SPTBN1 GOLGA8A PHLDB2 PDZD2	1.21e-04	185	184	6	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC6 DNAH2 DNAH1 ENO4 MTBP FHIP1A	1.21e-04	185	184	6	05bc89a566b0db90ae06506e067190a4739a0974
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OBSCN LAMC3 CHN1 BGN DAAM2 PDZD2	1.24e-04	186	184	6	888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMC3 MAP3K6 BGN SNCAIP PTPRZ1 DAAM2	1.28e-04	187	184	6	ddfc2d1d9fcc3d8e4d3d015576bb17eebf44ada9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 MAP2 SPTBN1 GOLGA8A FHIP1A PHLDB2	1.28e-04	187	184	6	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	COPD-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	PALD1 LAMC3 CHN1 BGN DAAM2 PDZD2	1.28e-04	187	184	6	406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LGMN IQGAP2 DISC1 SAMSN1 NLRP3 SLC45A4	1.28e-04	187	184	6	39b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	TRPM6 MMS22L CACNB4 SHROOM3 KAZN FHIP1A	1.32e-04	188	184	6	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	LGMN SRP72 RINT1 CLIC1 MTBP UNC80	1.32e-04	188	184	6	34873972dff9284dfcd26bb698c9d1df007f1cbb
ToppCell	Healthy/Control-B_memory\|Healthy/Control / Disease group and Cell class	BHLHE41 LARGE2 ZYG11A LGMN EML6 CHD7	1.32e-04	188	184	6	3aff07f77b2b15e7a30e47b30115178abe64474e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB4 MAP4K3 SPTBN2 EML6 TRPV6 KAZN	1.36e-04	189	184	6	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP2 MAP4K3 MAT2A CHN1 KAZN PDZD2	1.36e-04	189	184	6	ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LGMN IQGAP2 DISC1 SAMSN1 NLRP3 RBPJ	1.40e-04	190	184	6	f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LGMN IQGAP2 DISC1 NLRP3 RBPJ DAAM2	1.40e-04	190	184	6	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	(1)_T_cells-(1)_T_CD4_reg\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	LGMN GBP2 SAMSN1 CHN1 CLIC1 TLR5	1.40e-04	190	184	6	ff42af092173c2d4472bb9a02f5a334c272e05a0
ToppCell	Control-Myeloid-Transitioning_MDM\|Control / group, cell type (main and fine annotations)	IQGAP2 MAT2A SAMSN1 NLRP3 RBPJ UBASH3B	1.40e-04	190	184	6	d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 MAP2 SPTBN1 FHIP1A PHLDB2 PDZD2	1.40e-04	190	184	6	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPTAN1 SPTBN1 MPRIP MACF1 PHLDB2 SON	1.40e-04	190	184	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	PALD1 FNBP1 ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	1.44e-04	191	184	6	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 EML6 SLC45A4 IQCA1 TRPV6 KAZN	1.48e-04	192	184	6	fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FRYL SNCAIP TMTC3 VPS13A MACF1 GOLGA8A	1.52e-04	193	184	6	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	Immune-interstitial_macrophage_(C1Q_positive)\|World / Lineage, Cell type, age group and donor	LGMN IQGAP2 DISC1 SAMSN1 NLRP3 RBPJ	1.52e-04	193	184	6	64d598162a256ac6c9f8280c8a9133661dfbb10f
ToppCell	RA-08._Macrophage\|World / Chamber and Cluster_Paper	IQGAP2 SAMSN1 NLRP3 CSGALNACT2 RBPJ UBASH3B	1.52e-04	193	184	6	5fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCDC74B MAP2 IQCA1 PTPRZ1 CCDC74A KIF5A	1.52e-04	193	184	6	c3522693439c23830d8a3f20854539ccb7a666e0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 SPTBN1 SPTBN2 EML6 SLC45A4 TRPV6	1.56e-04	194	184	6	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D231\|Adult / Lineage, Cell type, age group and donor	FNBP1 LGMN IQGAP2 DISC1 SAMSN1 NLRP3	1.56e-04	194	184	6	800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FNBP1 IQGAP2 DISC1 SAMSN1 NLRP3 RBPJ	1.56e-04	194	184	6	663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LGMN IQGAP2 DISC1 SAMSN1 NLRP3 RBPJ	1.56e-04	194	184	6	1dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CACNB4 SHROOM3 TRIM67 MYH15 UNC80 ANKRD26P1	1.61e-04	195	184	6	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SPTAN1 SPTBN1 OBSCN MPRIP MACF1 GOLGA8A	1.61e-04	195	184	6	4bdedd924564a260841a9153604026b57487c83d
ToppCell	distal-Hematologic-Classical_Monocyte-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MAT2A SAMSN1 NLRP3 CFD CSGALNACT2 SERPINB2	1.61e-04	195	184	6	32c34741e35006b7238896fd04a497011297dd22
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CCDC74B MAT1A E2F7 ANKRD20A3P ENO4 CCDC74A	1.61e-04	195	184	6	e525b69145059b66417589601f7109af63730f3a
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CACNB4 SHROOM3 TRIM67 MYH15 UNC80 ANKRD26P1	1.61e-04	195	184	6	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	390C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	FNBP1 CCDC28B MCM5 MAP3K6 TRIP10 CEP350	1.61e-04	195	184	6	ecf7d9856a5b507ec17c325c9a772dc5a184bc8e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LGMN IQGAP2 DISC1 SAMSN1 NLRP3 RBPJ	1.61e-04	195	184	6	34a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCell	ASK452\|World / Donor, Lineage and Cell class of Lung cells from Dropseq	GBP2 SAMSN1 NLRP3 BGN CFD SERPINB2	1.61e-04	195	184	6	7efd9d3a3f5e7dfe9698a4143ce4a0f9bf3a862c
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_macrophage\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LGMN BAZ1B CFD RBPJ TBC1D23 SON	1.70e-04	197	184	6	e3349a381723393cd255f202afedd0c99037939b
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_macrophage-macrophage\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LGMN BAZ1B CFD RBPJ TBC1D23 SON	1.70e-04	197	184	6	e567886d69c6ea8dec87019c2ebc593793cb3107
ToppCell	distal-2-Hematologic-Classical_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MAT2A SAMSN1 NLRP3 CFD CSGALNACT2 SERPINB2	1.70e-04	197	184	6	9a1c9221904ad1e46e64e3785516804e87128adc
ToppCell	distal-Hematologic-IGSF21+_Dendritic-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LGMN IQGAP2 NLRP3 CFD RBPJ TLR5	1.70e-04	197	184	6	e77c91f5a1f5a292eda41abf3b1e31180f2c61e1
ToppCell	distal-3-Hematologic-IGSF21+_Dendritic\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LGMN IQGAP2 NLRP3 CFD RBPJ TLR5	1.70e-04	197	184	6	52e9dc35dd8cc2605fa4894bb16bb5c6086faa76
Disease	neutrophil count, eosinophil count	UBR2 HNF1A EML6 HECTD4 CHD7 ABCA7 NLRP3 SLC45A4 COQ8A MAP4K5	5.38e-07	213	172	10	EFO_0004833, EFO_0004842
Disease	neutrophil count, basophil count	UBR2 HNF1A EML6 HECTD4 CHD7 ABCA7 NLRP3 SLC45A4 COQ8A MAP4K5	8.52e-07	224	172	10	EFO_0004833, EFO_0005090
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	TDRD15 HNF1A DDX56 OGDH MAP4K5 ANKDD1B MACF1 TP53BP1	2.17e-06	144	172	8	EFO_0004611, EFO_0020943
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	TDRD15 HNF1A SHROOM3 MAP4K5 ANKDD1B MACF1 TP53BP1	2.96e-05	150	172	7	EFO_0004611, EFO_0020947
Disease	neutrophil percentage of leukocytes	PALD1 UBR2 HNF1A CHD7 SHOC2 ABCA7 NLRP3 SLC45A4 UBE2O TMTC3 COQ8A MAP4K5 UBASH3B	6.45e-05	610	172	13	EFO_0007990
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	TDRD15 HNF1A SHROOM3 MAP4K5 MACF1 TP53BP1	7.94e-05	121	172	6	EFO_0008595, EFO_0020943
Disease	Inherited neuropathies	CACNB4 SPTBN2 COQ8A KIF5A	8.65e-05	40	172	4	C0598589
Disease	hematocrit	RALGAPA1 ZYG11A TDRD15 HNF1A NR2E3 BRPF3 SHROOM3 RIPK3 MAT1A HECTD4 DNAH2 ZBTB7B MPRIP ACSBG1 MAP4K5 FKBP8 TP53BP1	9.35e-05	1011	172	17	EFO_0004348
Disease	Intrahepatic cholestasis of pregnancy	HNF1A SHROOM3 MAP4K5	1.03e-04	16	172	3	EFO_0009048
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	HNF1A SHROOM3 MAP4K5 ANKDD1B MACF1 TP53BP1	1.04e-04	127	172	6	EFO_0008595, EFO_0020947
Disease	granulocyte count	HNF1A EML6 HECTD4 CHD7 NLRP3 SLC45A4 COQ8A MAP4K5	1.29e-04	254	172	8	EFO_0007987
Disease	Hypertriglyceridemia	TDRD15 BAZ1B MAP4K5	1.76e-04	19	172	3	EFO_0004211
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTBN1 SPTBN2	2.01e-04	4	172	2	DOID:0050882 (implicated_via_orthology)
Disease	C-reactive protein measurement	NBPF3 UBR2 TDRD15 HNF1A MMS22L CYP3A4 BAZ1B CCDC168 CHD7 IL18RAP NLRP3 MAP4K5 RAVER2 RNF10 MACF1 PSME3 MAPK6 TP53BP1	2.53e-04	1206	172	18	EFO_0004458
Disease	aspartate aminotransferase measurement	HNF1A SHROOM3 IQGAP2 HECTD4 OBSCN DNAH2 SHOC2 IL18RAP NLRP3 SLC45A4 NF1 MAP4K5 RBPJ KAZN UBASH3B	2.82e-04	904	172	15	EFO_0004736
Disease	urate measurement, bone density	TRPM6 FNBP1 COL5A1 KIF6 ABCB5 OGDH DNAH1 EYS MAP4K5 USP40 KAZN PDZD2	2.95e-04	619	172	12	EFO_0003923, EFO_0004531
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	HNF1A HECTD4 NLRP3 MAP4K5	3.23e-04	56	172	4	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	response to platinum based chemotherapy, cytotoxicity measurement	EYS SNCAIP	3.34e-04	5	172	2	EFO_0004647, EFO_0006952
Disease	serum alpha-1-antitrypsin measurement	HNF1A MAP4K5	3.34e-04	5	172	2	EFO_0005415
Disease	lactosyl-N-palmitoyl-sphingosine (d18:1/16:0) measurement	CHD7 ABCA7	3.34e-04	5	172	2	EFO_0800429
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	TDRD15 HNF1A SHROOM3 DNAH1 MAP4K5 MACF1 TP53BP1	3.58e-04	224	172	7	EFO_0004530, EFO_0008317
Disease	triglycerides in IDL measurement	TDRD15 HNF1A MAP4K5 TP53BP1	3.70e-04	58	172	4	EFO_0022149
Disease	fibrinogen measurement, factor VII measurement	HNF1A HECTD4 NLRP3 MAP4K5	3.70e-04	58	172	4	EFO_0004619, EFO_0004623
Disease	epiandrosterone sulfate measurement	TRIM4 CYP3A4 CYP3A43	4.07e-04	25	172	3	EFO_0021120
Disease	cholesterol to total lipids in IDL percentage	MAP4K5 ANKDD1B MACF1 TP53BP1	4.22e-04	60	172	4	EFO_0022233
Disease	Lissencephaly	TMTC3 MACF1	4.99e-04	6	172	2	C0266463
Disease	magnesium measurement	TRPM6 SHROOM3 CCDC168 ATE1	6.06e-04	66	172	4	EFO_0004845
Disease	1-palmitoyl-GPE (16:0) measurement	MAP4K5 TP53BP1	6.96e-04	7	172	2	EFO_0800245
Disease	cholesteryl ester measurement	TDRD15 HNF1A BAZ1B EYS MAP4K5 ANKDD1B TP53BP1	8.09e-04	257	172	7	EFO_0010351
Disease	alkaline phosphatase measurement	NBPF3 RALGAPA1 TDRD15 HNF1A SPTBN1 BAZ1B ERGIC2 NLRP3 NF1 SLF2 MAP4K5 RNF10 MACF1 UBASH3B TP53BP1	9.27e-04	1015	172	15	EFO_0004533
Disease	fatty acid measurement	UBR2 TDRD15 HNF1A MMS22L BAZ1B MAP4K5 MACF1 PSME3 TP53BP1	1.09e-03	436	172	9	EFO_0005110
Disease	low density lipoprotein cholesterol measurement, C-reactive protein measurement	HNF1A HECTD4 MAP4K5	1.11e-03	35	172	3	EFO_0004458, EFO_0004611
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	TDRD15 SHROOM3 DNAH1 MAP4K5 MACF1 TP53BP1	1.17e-03	200	172	6	EFO_0004611, EFO_0020945
Disease	lactosyl-N-nervonoyl-sphingosine (d18:1/24:1) measurement	CHD7 ABCA7	1.18e-03	9	172	2	EFO_0800517
Disease	level of Sterol ester (27:1/16:1) in blood serum	HNF1A MAP4K5	1.18e-03	9	172	2	OBA_2045190
Disease	calcium measurement	TRPM6 NBPF3 MAP4K3 SPTBN1 DNAH2 MAP4K5 RBPJ USP40 MACF1 KIF5A UBASH3B	1.20e-03	628	172	11	EFO_0004838
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	TDRD15 HNF1A BAZ1B DDX56 MAP4K5	1.28e-03	137	172	5	EFO_0004611, EFO_0008591
Disease	testosterone measurement	TRPM6 HNF1A SHROOM3 TRIM4 CYP3A4 GLYCTK DNAH2 TTC27 BAZ1B CHD7 ZBTB7B NF1 MAP4K5 ANKDD1B MACF1 DAAM2 KAZN	1.31e-03	1275	172	17	EFO_0004908
Disease	total blood protein measurement	IQGAP2 MAP4K3 SLC45A4 DNAH1 MAP4K5 RBPJ MACF1 LRRC8B UBASH3B	1.34e-03	449	172	9	EFO_0004536
Disease	phosphatidylcholine measurement	TDRD15 COL5A1 HNF1A KIF6 CHD7 MAP4K5 MACF1	1.44e-03	284	172	7	EFO_0010226
Disease	level of Sterol ester (27:1/18:3) in blood serum	HNF1A MAP4K5	1.47e-03	10	172	2	OBA_2045193
Disease	level of Phosphatidylcholine (18:0_22:5) in blood serum	HNF1A MAP4K5	1.47e-03	10	172	2	OBA_2045096
Disease	intermediate density lipoprotein measurement	TDRD15 HNF1A BAZ1B DDX56	1.70e-03	87	172	4	EFO_0008595
Disease	follistatin measurement	MAP4K5 TP53BP1	1.79e-03	11	172	2	EFO_0010614
Disease	lymphocyte percentage of leukocytes	PALD1 UBR2 HNF1A CHD7 IL18RAP ABCA7 NLRP3 UBE2O TMTC3 COQ8A UBASH3B	1.88e-03	665	172	11	EFO_0007993
Disease	sleep duration, low density lipoprotein cholesterol measurement	TDRD15 HNF1A DDX56 OGDH	2.01e-03	91	172	4	EFO_0004611, EFO_0005271
Disease	triglycerides in large LDL measurement	TDRD15 MAP4K5 TP53BP1	2.02e-03	43	172	3	EFO_0022319
Disease	red blood cell density measurement	RALGAPA1 ZYG11A HNF1A SHROOM3 SPTBN1 FKBP9 DNAH2 TMTC3 ACSBG1 KLHL30 MAP4K5 MRPL40 UBASH3B	2.03e-03	880	172	13	EFO_0007978
Disease	free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	TDRD15 HNF1A TTC27 BAZ1B MAP4K5 TP53BP1 TANGO6	2.08e-03	303	172	7	EFO_0004612, EFO_0020945
Disease	cholesteryl ester measurement, very low density lipoprotein cholesterol measurement	TDRD15 HNF1A BAZ1B DDX56 MAP4K5 TP53BP1	2.12e-03	225	172	6	EFO_0008317, EFO_0010351
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	TDRD15 HNF1A DDX56 MAP4K5 MACF1 TP53BP1	2.12e-03	225	172	6	EFO_0008317, EFO_0020947
Disease	methionine sulfone measurement	CYP3A4 CYP3A43	2.15e-03	12	172	2	EFO_0800072
Disease	response to carboplatin, methylcobalamin deficiency type cblE, response to antineoplastic agent	LRRC8B KAZN	2.15e-03	12	172	2	GO_0097327, GO_0097328, MONDO_0009354
Disease	alcohol consumption measurement, alcohol drinking	HECTD4 MAP4K5	2.15e-03	12	172	2	EFO_0004329, EFO_0007878
Disease	cortical surface area measurement	TRPM6 PALD1 KIF6 SHROOM3 IQGAP2 MAP2 SPTBN1 LAMC3 FRYL CHD7 SLC45A4 MPRIP CSGALNACT2 MACF1 MAPK6 TANGO6 PDZD2	2.31e-03	1345	172	17	EFO_0010736
Disease	fibrinogen measurement, tissue plasminogen activator measurement	HNF1A HECTD4 NLRP3	2.31e-03	45	172	3	EFO_0004623, EFO_0004791
Disease	fibrinogen measurement, plasminogen activator inhibitor 1 measurement	HNF1A HECTD4 NLRP3	2.31e-03	45	172	3	EFO_0004623, EFO_0004792
Disease	saturated fatty acids measurement	HNF1A MAP4K5 TP53BP1	2.31e-03	45	172	3	EFO_0022304
Disease	lipid measurement, intermediate density lipoprotein measurement	TDRD15 HNF1A BAZ1B DDX56	2.44e-03	96	172	4	EFO_0004529, EFO_0008595
Disease	carbohydrate measurement	SAMSN1 ATE1 EYS	2.46e-03	46	172	3	EFO_0004998
Disease	cystatin C measurement	HNF1A NR2E3 SHROOM3 MAT1A HECTD4 BAZ1B DNAH1 MAP4K5	2.57e-03	402	172	8	EFO_0004617
Disease	serum albumin measurement	HNF1A SHROOM3 MAP4K3 NLRP3 SLC45A4 MAP4K5 RBPJ MACF1 UBASH3B TP53BP1	2.59e-03	592	172	10	EFO_0004535
Disease	mean reticulocyte volume	ZYG11A IQGAP2 DNAH2 NEB ABCA7 CEP350 TMTC3 ACSBG1 MAP4K5 VPS13A INTS4 PCM1	2.63e-03	799	172	12	EFO_0010701
Disease	mean platelet volume	IQGAP2 PCDHGB3 SPTBN1 EML6 FRYL CHD7 SLC45A4 MPRIP CLIC1 MAP4K5 INTS4 UBASH3B ESPL1 PCDHGC3	2.70e-03	1020	172	14	EFO_0004584
Disease	total lipids in lipoprotein particles measurement	TDRD15 HNF1A MAP4K5	2.78e-03	48	172	3	EFO_0022309
Disease	phosphoglycerides measurement	TDRD15 HNF1A MAP4K5	2.78e-03	48	172	3	EFO_0022291
Disease	alpha fetoprotein measurement	HNF1A MAP4K5 TET1 TP53BP1	2.83e-03	100	172	4	EFO_0010583
Disease	Asbestosis	NLRP3 CFD	2.94e-03	14	172	2	C0003949
Disease	Pulmonary Fibrosis - from Asbestos Exposure	NLRP3 CFD	2.94e-03	14	172	2	C2930617
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	TDRD15 HNF1A DNAH1 MAP4K5 MACF1 TP53BP1	3.10e-03	243	172	6	EFO_0004612, EFO_0020944
Disease	triglycerides to total lipids in medium LDL percentage	MAP4K5 ANKDD1B TP53BP1	3.12e-03	50	172	3	EFO_0022334
Disease	cholesteryl esters to total lipids in IDL percentage	MAP4K5 MACF1 TP53BP1	3.12e-03	50	172	3	EFO_0022247
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	HNF1A MAP4K5 MACF1 TP53BP1	3.15e-03	103	172	4	EFO_0008595, EFO_0020944
Disease	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	TDRD15 BAZ1B MAP4K5	3.30e-03	51	172	3	EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Disease	triglycerides to total lipids in large LDL percentage	MAP4K5 ANKDD1B TP53BP1	3.30e-03	51	172	3	EFO_0022331
Disease	liver volume	MAP4K5 TP53BP1	3.37e-03	15	172	2	EFO_0600048
Disease	RASopathy	SHOC2 NF1	3.37e-03	15	172	2	cv:C5555857
Disease	YKL40 measurement	OPTC MAP4K5	3.37e-03	15	172	2	EFO_0004869
Disease	lipid metabolism disorder (implicated_via_orthology)	MAT1A MAT2A	3.37e-03	15	172	2	DOID:3146 (implicated_via_orthology)
Disease	myeloid white cell count	UBR2 HNF1A SPTBN1 EML6 HECTD4 CHD7 ABCA7 NLRP3 SLC45A4 UBE2O MAP4K5 RBPJ UBASH3B	3.48e-03	937	172	13	EFO_0007988
Disease	episodic memory	TRPM6 EML6 CEP350	3.49e-03	52	172	3	EFO_0004333
Disease	Familial thoracic aortic aneurysm and aortic dissection	COL5A1 MAT2A BGN	3.68e-03	53	172	3	C4707243
Disease	total phospholipids in lipoprotein particles measurement	TDRD15 HNF1A MAP4K5	3.68e-03	53	172	3	EFO_0022315
Disease	triglycerides in HDL measurement	HNF1A MAP4K5 TP53BP1	3.68e-03	53	172	3	EFO_0022317
Disease	serum metabolite measurement	NBPF3 RALGAPA1 TDRD15 LGMN HNF1A RIPK1 TRIM4 CYP3A4 CYP3A43 LAMC3 ABCA7 SLC45A4 MAP4K5	3.73e-03	945	172	13	EFO_0005653
Disease	monocyte percentage of leukocytes	UBR2 ZYG11A CHD7 NLRP3 NF1 COQ8A MAP4K5 RBPJ TLR5 LRRC8B UBASH3B	3.87e-03	731	172	11	EFO_0007989
Disease	total lipids in medium VLDL	TDRD15 MAP4K5 TP53BP1	3.88e-03	54	172	3	EFO_0022153
Disease	triglycerides in medium HDL measurement	HNF1A MAP4K5 TP53BP1	3.88e-03	54	172	3	EFO_0022321
Disease	triglycerides in medium VLDL measurement	TDRD15 MAP4K5 TP53BP1	4.09e-03	55	172	3	EFO_0022155
Disease	Ischemic stroke, fibrinogen measurement	HNF1A HECTD4 NLRP3	4.09e-03	55	172	3	EFO_0004623, HP_0002140
Disease	triglycerides in very large HDL measurement	HNF1A MAP4K5 TP53BP1	4.09e-03	55	172	3	EFO_0022324
Disease	triglyceride measurement, intermediate density lipoprotein measurement	HNF1A SHROOM3 MAP4K5 TP53BP1	4.11e-03	111	172	4	EFO_0004530, EFO_0008595
Disease	response to statin	TDRD15 DISC1 ABCB5	4.30e-03	56	172	3	GO_0036273
Disease	triglycerides in LDL measurement	TDRD15 MAP4K5 TP53BP1	4.30e-03	56	172	3	EFO_0022320
Disease	cholesterol to total lipids in large LDL percentage	TDRD15 MAP4K5 ANKDD1B	4.30e-03	56	172	3	EFO_0022235
Disease	response to phenylephrine	IQGAP2 NEK11	4.34e-03	17	172	2	EFO_0010152
Disease	protein C measurement	BAZ1B MAP4K5	4.34e-03	17	172	2	EFO_0004633
Disease	oral motor function measurement	LGMN SHROOM3	4.34e-03	17	172	2	EFO_0021793
Disease	heel bone mineral density, urate measurement	EML6 FKBP9 PCM1 PHLDB2 SON	4.37e-03	182	172	5	EFO_0004531, EFO_0009270
Disease	free cholesterol measurement	TDRD15 HNF1A DDX56 MAP4K5	4.38e-03	113	172	4	EFO_0008591

Protein segments in the cluster

Peptide	Gene	Start	Entry
ILHADIKPDNILVNE	PRPF4B	811	Q13523
AVILLEHGANPNLKD	ANKRD20A1	116	Q5TYW2
GAHIEALDKDNNTPL	ANKRD20A1	156	Q5TYW2
LQLVALDADTINHPA	CACNB1	316	Q02641
NECIAQLKDLLPEHL	BHLHE41	61	Q9C0J9
PLDEIKEAANAANIH	ABCB5	1121	Q2M3G0
AVILLEHGANPNLKD	ANKRD20A4P	116	Q4UJ75
GAHIEALDKDNNTPL	ANKRD20A4P	156	Q4UJ75
SQKELDELLNCLHPQ	BAZ1B	996	Q9UIG0
NPLDGTEKIAIDHNQ	ERGIC2	231	Q96RQ1
AVILLEHGANPNLKD	ANKRD20A5P	116	A0PJZ0
THLLPENENELEKFI	C19orf18	161	Q8NEA5
EVNENILHKPSILQE	ABITRAM	121	Q9NX38
TLDLLQEKDPAHIFA	BRPF3	601	Q9ULD4
DELTPFLLAVHEQKQ	ANKRD26P1	181	Q6NSI1
HLKADPDNLQALHTL	CAPN5	596	O15484
APDQQHLSTEDLIKA	CEP76	41	Q8TAP6
SQKADLEEEPLLHNS	CCDC74A	201	Q96AQ1
PQKADLEEEPLLHNS	CCDC74B	201	Q96LY2
LDADTINHPAQLIKT	CACNB4	311	O00305
ILNDPELSFLDAHKN	CHD7	2116	Q9P2D1
EDLEQEKISLHFQLP	DISC1	381	Q9NRI5
HQTQEALGALLDKEP	IQCA1	11	Q86XH1
AQEPLHSLLEAAEDL	ABCA7	176	Q8IZY2
CSNHEEVSLLEKLQP	CCNB3	181	Q8WWL7
DLNQQDVLGEAPLHK	ANKRD37	56	Q7Z713
LPQDSNCQEVHDLLK	RAVER2	76	Q9HCJ3
LKDPEHVEALQDQSQ	NR2E3	336	Q9Y5X4
IADLPHLQDSFVDKL	INTS4	766	Q96HW7
LADQDIFNAVIKEHP	LARGE2	291	Q8N3Y3
PDQLETLEAQLKAHL	PALD1	571	Q9ULE6
HDGAPLALQQKLEEV	KLHL30	256	Q0D2K2
AVILLEHGANPNLKD	ANKRD20A2P	116	Q5SQ80
GAHIEALDKDNNTPL	ANKRD20A2P	156	Q5SQ80
SQPDTIDHDLLLLQL	CFD	106	P00746
NLHVADNANLDPVDK	ERCC6	696	P0DP91
SELQHLPEAAKVNLA	DAAM2	861	Q86T65
LAIELLDKVNNPDHS	MAP4K3	281	Q8IVH8
EHLALSLFPDVLENK	IL18RAP	431	O95256
SHLLNDEDLTQAKPI	MPRIP	31	Q6WCQ1
HNPIVQSLEDLEDQK	KAZN	361	Q674X7
LPDNHKNALAANIDE	MAIP1	186	Q8WWC4
INNSLILSEDIDPHK	EYS	3081	Q5T1H1
QPAEHLQLLEEAAKE	MCM5	91	P33992
EDEHLLQAISKANPV	MTMR6	216	Q9Y217
FLPSANEHLKEDLNL	GLRX3	121	O76003
DVASHVLDLLNFLKP	MMS22L	546	Q6ZRQ5
DCLLLPHAVLQQEKE	MMS22L	971	Q6ZRQ5
VLDAHLQQDPDAKVA	MAT2A	41	P31153
LHEASENLKNVPLLD	ERVMER34-1	461	Q9H9K5
SIQKLHLADAQDVPN	CCDC28A	256	Q8IWP9
NEDVQALKELILHNP	DDX56	201	Q9NY93
LATHPDVQQKLQEEI	CYP3A4	321	P08684
AVLEQELPALAENLH	MAP3K6	1006	O95382
ILEDEQPLNSAAHKE	PCM1	1876	Q15154
LPLADIDHLEQEKQI	MLH3	1401	Q9UHC1
HALQDLILPENQLEA	OPTC	201	Q9UBM4
HEPTDVVDKLNDLNS	MAPK6	541	Q16659
HISESQDLDDLLQKP	PDZD2	1776	O15018
DLPETLNELHLDHNK	BGN	226	P21810
HIDLSAAPAKQFNLE	FRYL	2211	O94915
ANLEAQLLSKLDHPA	NEK11	76	Q8NG66
EDPDQNIHLKNLTLH	KIF6	176	Q6ZMV9
QISDAVLDAHLKQDP	MAT1A	36	Q00266
LKELENLSPEEAAHQ	HNF1A	86	P20823
AHLEQLKEEELNPDF	GBP2	246	P32456
EPLNTLINKLIHSDE	PTPRZ1	1321	P23471
HLIFADSLQEIQPDL	PCDHGB3	661	Q9Y5G1
ASLPIHIKVLDANDN	PCDHGC3	226	Q9UN70
HLLSNTILIKPDEND	HECTD4	456	Q9Y4D8
NQHLQALLTPDEPDK	NBPF1	666	Q3BBV0
VVDHPALAFLEENLK	LRRC8B	476	Q6P9F7
DTAELLSLENHPAKQ	MACF1	741	Q9UPN3
DKTPLHANELNEIDA	OBSCN	3041	Q5VST9
FDVALLDLHNPKDSI	FKBP9	246	O95302
AQHLVQKLSPENDDD	NBPF3	211	Q9H094
AQPNVDKLVEDHLAV	OGDH	116	Q02218
AIHPNTILNSKLEEA	OSGIN2	46	Q9Y236
ILKSPDEASQLLDDH	DNAH1	1186	Q9P2D7
AKLAEFLAEHPNVTL	APOBEC3F	101	Q8IUX4
AVILLEHGANPNLKD	ANKRD20A3P	116	Q5VUR7
GAHIEALDKDNNTPL	ANKRD20A3P	156	Q5VUR7
APSDLLEFLHSQIDK	CSGALNACT2	116	Q8N6G5
SLVLEHQPDNIKALF	FKBP8	296	Q14318
PEFLKELAALAQEHS	FHIP1A	1011	Q05DH4
PSNSHLVLVLDKDLQ	ESPL1	1886	Q14674
KLDLLPENHAVFLQE	FER1L6-AS2	91	Q96M78
AAKILIEESQDAPDH	E2F7	311	Q96AV8
LATHPDVQQKLQEEI	CYP3A43	321	Q9HB55
DAQLHELAAELQIPD	GLYCTK	371	Q8IVS8
PASLDHKLAEVSQNI	FNBP1	451	Q96RU3
LHLQDQDSVKDAVPD	DHX57	781	Q6P158
HLLANKFDPKVDDNA	GCNT3	406	O95395
DSLENVPALHLLKEL	CEP350	2221	Q5VT06
LSIQDDAFINPHLAK	COQ8A	281	Q8NI60
SLNHALELSVPEKVN	ACSBG1	56	Q96GR2
AAQPADLLKVLDFHN	COL5A1	36	P20908
TEAADDIINNHLPKL	AMDHD1	201	Q96NU7
DLIFESLPENASHKL	ATE1	256	O95260
VHENALPELAKAEEA	ENO4	111	A6NNW6
AEDQAKLFPLHQETA	KIF5A	1016	Q12840
LDSLCLHQKLDSQEP	CXorf38	296	Q8TB03
NDDIISLALHPDKTL	EML6	61	Q6ZMW3
EEHKVLLEAAPQLSQ	CCDC168	1466	Q8NDH2
EALQPHLAAIATELA	DNAAF5	466	Q86Y56
DPDEQLETLHEALKL	CHN1	371	P15882
NSIQKLHLAENAEPE	CCDC28B	181	Q9BUN5
KTDLQELEHIFPNLH	CEP295	2061	Q9C0D2
ADNAQKDLEEALPAL	DNAH2	3081	Q9P225
LAVELLDKVNNPDNH	MAP4K5	286	Q9Y4K4
EAAENLHQLSDKLPA	MTBP	146	Q96DY7
THEDPQLLEATLAQL	PIDD1	71	Q9HB75
PDAILQAQAADKIHS	SERPINB2	91	P05120
FDPQTHDLLLNEKLD	PCDHB6	76	Q9Y5E3
LLHPDCKLQVLELDN	NLRP3	936	Q96P20
QAVQFIHKDSADLLP	NRIP3	31	Q9NQ35
QLAEPQSDLEELKHE	GOLGA8A	386	A7E2F4
ALEELQLESPKLHAE	MRPL40	146	Q9NQ50
PHANETKEILELNSL	TDRD6	1821	O60522
DVALLQLEPHDLSNV	PRSS29P	161	A6NIE9
DTSLDIQHVLDKLQP	TDRD15	221	B5MCY1
HLQALLTLDEPDKSQ	NBPF8	91	Q3BBV2
AQHLVQKLSPENDED	NBPF12	426	Q5TAG4
NEHLQALLTPDEPDK	NBPF12	666	Q5TAG4
VQLAEPDLEQAAHLI	TACO1	266	Q9BSH4
NLHEDIQKLNCNPEL	SEC24A	371	O95486
IKESHLIELNIENPD	SAMSN1	276	Q9NSI8
LLLEHQDAIAPEKND	IQGAP2	1221	Q13576
QKELHDLLLVSANPS	MYH15	306	Q9Y2K3
PALILEEKNEANHLG	MARCOL	36	A0A1B0GUY1
NLHLPQTEEAKAEAL	POLR3A	506	O14802
LDLQHNELLDLPDTI	SHOC2	266	Q9UQ13
VHQDKSLADILDPDS	SHROOM3	1676	Q8TF72
ISLLPHLAADNLDKI	SNCAIP	331	Q9Y6H5
LDEKHEDVPNASNLQ	SLF2	1026	Q8IX21
KAIELLQEFSDQHPE	SRP72	356	O76094
LGEKDLPHSVIDNDN	PHLDB2	286	Q86SQ0
PENILVDNDFHIKIA	RIPK1	141	Q13546
KLESEHPDQAQAILS	SPTBN1	1021	Q01082
PLHEKNLEDNLQSLA	TET1	1606	Q8NFU7
LPQAPANAHLKDLDE	AATF	441	Q9NY61
LIQDLHLKDLNQPDE	ANKDD1B	186	A6NHY2
FLLSENVDLHQKVEP	ANKDD1B	286	A6NHY2
ANAVDPKNDSHVLIE	TRIP10	256	Q15642
NELTLADCNLLPKLH	CLIC1	171	O00299
LDSFLKEPILNIHDL	PSME3	41	P61289
ETLLDNHLNEAKVPN	SLC45A4	371	Q5BKX6
SAELALLLHPVDQAN	UHRF1BP1L	866	A0JNW5
LDSEPLLQAIHQLDF	TRIM67	491	Q6ZTA4
SHLALPEEVSLQEQL	ZNF460	66	Q14592
LHQDNLAPGLDSQDK	ZBTB7B	321	O15156
DFSAPKINLEIELHN	VPS13A	271	Q96RL7
QLPVHEDTQFEALLK	UNC80	2011	Q8N2C7
QCKLLAQPAENHEEL	UNC80	2856	Q8N2C7
AHLLDGQDKAEQVLP	TRPM6	1411	Q9BX84
LEPANEIKNLLDEHT	RALGAPA1	541	Q6GYQ0
HLLNQTDKSHLPEDL	RLF	856	Q13129
TLPEAEALLAQHAAL	SPTBN2	1096	O15020
NHTEFLDEKIQPILD	RINT1	346	Q6NUQ1
SNVLLDPELHVKLAD	RIPK3	146	Q9Y572
FAAKLIQEQHPEEEL	SPTAN1	211	Q13813
ALEQQLAEEKHTPES	RNF10	351	Q8N5U6
DGILDLPEQNTIHKD	TBC1D23	71	Q9NUY8
LETHALLEKAQALPN	UBE2O	1146	Q9C0C9
EPDDVAKLHAQLALE	TANGO6	1056	Q9C0B7
ESPLLLAAKDNDVQA	TRPV6	86	Q9H1D0
HEQQKLPAATLALEE	NF1	1721	P21359
DDLLNLIHAPSVVAK	RHPN2P1	376	A8MT19
DSPQKLAILDQELEH	TP53BP1	726	Q12888
DDNSLAHPNLFIEKA	RSRC1	296	Q96IZ7
TALLDADDPVSQLHK	RBPJ	271	Q06330
HKDQTAALPLAAEET	MAP2	116	P11137
KHANLLDIPLEDCDQ	ZUP1	176	Q96AP4
HLNPLESIQLELDSV	TSPYL6	201	Q8N831
EDVHLENQPKIQELL	SCN11A	1076	Q9UI33
KSHPEVLIAEALAAN	ZFP91	451	Q96JP5
AIDQKPELQLDSLHA	TARBP1	821	Q13395
PELAEDDANLLHKHI	WASF1	211	Q92558
ASHLPTLEKLAQNID	UBASH3B	221	Q8TF42
DDVSAILDNKDLHPS	TMTC3	31	Q6ZXV5
QVAVNLAEDTAHPKL	TRIM4	306	Q9C037
LSHNDLPANLEILDI	TLR5	541	O60602
TPQEHLTKNLELNDD	TTC27	306	Q6P3X3
KLFASLVPNDSHEEL	UBR2	1391	Q8IWV8
HLKVTLAEQDPDELN	POMZP3	121	Q6PJE2
NLKDLQSEEEIDHPL	USP40	331	Q9NVE5
KLIELNATAVHADLP	ZYG11A	126	Q6WRX3
SDLAFHLLQQKDILP	ZYG11A	271	Q6WRX3
QPSLHDLTQDKLTLD	ZFC3H1	1011	O60293
LDECKIVPQNHSLLE	nan	126	Q499Y3
AKDIHLDLPSNNNLV	SON	1661	P18583
FLKHQAEAQPEDLSL	ZNF500	156	O60304
LAEQLFHPKALAELT	GEMIN4	21	P57678
DKQNLEAILHSLPEN	LAMC3	1556	Q9Y6N6
FPNEDLHVKDLNETI	LGMN	156	Q99538
LSPAAELHLIFNNKE	MYOM3	1031	Q5VTT5
IPDNLEQLHLKEATE	NEB	5881	P20929