Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein phosphatase regulator activity

PPP1R2 PPP1R2B PPP1R2P1 RCAN3 PPP6R3

1.47e-05100625GO:0019888
GeneOntologyMolecularFunctionphosphatase regulator activity

PPP1R2 PPP1R2B PPP1R2P1 RCAN3 PPP6R3

2.66e-05113625GO:0019208
GeneOntologyMolecularFunctionretromer complex binding

WASHC2C WASHC2A

4.20e-0410622GO:1905394
GeneOntologyMolecularFunctionprotein phosphatase inhibitor activity

PPP1R2 PPP1R2B PPP1R2P1

5.04e-0450623GO:0004864
GeneOntologyMolecularFunctionphosphatase inhibitor activity

PPP1R2 PPP1R2B PPP1R2P1

6.32e-0454623GO:0019212
GeneOntologyBiologicalProcessmesenchyme migration

ACTA1 ACTA2 ACTC1

2.58e-075623GO:0090131
GeneOntologyBiologicalProcessregulation of phosphatase activity

PPP1R2 PPP1R2B PPP1R2P1 HTT PPP6R3

2.86e-0674625GO:0010921
GeneOntologyBiologicalProcessregulation of dephosphorylation

PPP1R2 PPP1R2B PPP1R2P1 HTT PPP6R3

4.15e-05128625GO:0035303
GeneOntologyBiologicalProcessmesenchyme morphogenesis

ACTA1 ACTA2 ACTC1 HTT

4.37e-0565624GO:0072132
GeneOntologyBiologicalProcessprotein dephosphorylation

PPP1R2 PPP1R2B PPP3CB PPP1R2P1 HTT PPP6R3

1.18e-04256626GO:0006470
GeneOntologyBiologicalProcessribonucleoprotein complex biogenesis

NOP58 URB1 GNL3L TSR1 GEMIN8 ZNF622 USP4 SNRNP200

1.48e-04515628GO:0022613
GeneOntologyBiologicalProcessskeletal muscle thin filament assembly

ACTA1 ACTC1

1.85e-047622GO:0030240
HumanPhenoDisinhibition

MYT1L KMT2C FRMPD4 GLDC ASXL3 NSD1 ABCA7 CIC PUS7 LUZP1 HTT ZNF292

1.69e-058072112HP:0000734
HumanPhenoInappropriate behavior

MYT1L KMT2C FRMPD4 GLDC ASXL3 NSD1 ABCA7 CIC PUS7 LUZP1 HTT ZNF292

1.69e-058072112HP:0000719
HumanPhenoAbnormal response to social norms

MYT1L KMT2C FRMPD4 GLDC ASXL3 NSD1 ABCA7 CIC PUS7 LUZP1 HTT ZNF292

1.69e-058072112HP:5200123
HumanPhenoSocial disinhibition

MYT1L KMT2C FRMPD4 GLDC ASXL3 NSD1 ABCA7 CIC PUS7 LUZP1 HTT ZNF292

1.69e-058072112HP:5200029
HumanPhenoAbnormally increased volition

MYT1L KMT2C FRMPD4 GLDC ASXL3 NSD1 ABCA7 CIC PUS7 LUZP1 HTT ZNF292

3.68e-058692112HP:5200263
HumanPhenoAbnormal social development

MYT1L KMT2C FRMPD4 GLDC ASXL3 NSD1 ABCA7 CIC PUS7 LUZP1 HTT ZNF292

5.80e-059082112HP:0025732
HumanPhenoVentriculomegaly

MYT1L KMT2C ASXL3 ACTA2 NSD1 NUP188 ZBTB11 PUS7 LUZP1 HTT ZNF292

9.20e-057902111HP:0002119
HumanPhenoAggressive behavior

MYT1L KMT2C FRMPD4 GLDC ASXL3 NSD1 PUS7 LUZP1 HTT

1.01e-04516219HP:0000718
HumanPhenoAbnormal aggressive, impulsive or violent behavior

MYT1L KMT2C FRMPD4 GLDC ASXL3 NSD1 PUS7 LUZP1 HTT

1.01e-04516219HP:0006919
HumanPhenoReduced impulse control

MYT1L KMT2C FRMPD4 GLDC ASXL3 NSD1 ABCA7 CIC PUS7 LUZP1 HTT ZNF292

2.13e-0410322112HP:5200045
HumanPhenoTall stature

KMT2C ASXL3 ACTA1 ACTA2 NSD1 CIC

2.16e-04225216HP:0000098
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

4.36e-0812594PF15371
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

4.36e-0812594IPR027970
DomainACTINS_1

ACTA1 ACTA2 ACTC1

1.66e-068593PS00406
DomainFAM21

WASHC2C WASHC2A

9.81e-062592IPR027308
DomainARM-type_fold

GPRASP1 URB1 CEBPZ NUP188 HTT PPP6R3 KPNB1 XPO7

1.07e-05339598IPR016024
DomainActin_CS

ACTA1 ACTA2 ACTC1

1.63e-0516593IPR004001
DomainACTINS_2

ACTA1 ACTA2 ACTC1

1.97e-0517593PS00432
DomainActin/actin-like_CS

ACTA1 ACTA2 ACTC1

2.36e-0518593IPR020902
DomainACTINS_ACT_LIKE

ACTA1 ACTA2 ACTC1

2.80e-0519593PS01132
DomainFAM21/CAPZIP

WASHC2C WASHC2A

2.94e-053592IPR029341
DomainCAP-ZIP_m

WASHC2C WASHC2A

2.94e-053592PF15255
DomainActin

ACTA1 ACTA2 ACTC1

1.26e-0431593IPR004000
DomainActin

ACTA1 ACTA2 ACTC1

1.26e-0431593PF00022
DomainACTIN

ACTA1 ACTA2 ACTC1

1.26e-0431593SM00268
DomainZF_PHD_2

KMT2C ASXL3 NSD1 SP140

2.31e-0495594PS50016
DomainZF_PHD_1

KMT2C ASXL3 NSD1 SP140

2.40e-0496594PS01359
DomainIMPORTIN_B_NT

KPNB1 XPO7

8.71e-0414592PS50166
DomainIBN_N

KPNB1 XPO7

1.00e-0315592PF03810
DomainPost-SET_dom

KMT2C NSD1

1.14e-0316592IPR003616
DomainPostSET

KMT2C NSD1

1.14e-0316592SM00508
DomainIBN_N

KPNB1 XPO7

1.14e-0316592SM00913
DomainPOST_SET

KMT2C NSD1

1.14e-0316592PS50868
DomainImportin-beta_N

KPNB1 XPO7

1.29e-0317592IPR001494
DomainARM-like

GPRASP1 HTT PPP6R3 KPNB1 XPO7

1.61e-03270595IPR011989
DomainPHD

KMT2C NSD1 SP140

1.72e-0375593PF00628
DomainZnf_PHD-finger

KMT2C NSD1 SP140

2.00e-0379593IPR019787
DomainPHD

KMT2C NSD1 SP140

2.80e-0389593SM00249
DomainZnf_PHD

KMT2C NSD1 SP140

2.99e-0391593IPR001965
DomaincEGF

LTBP1 LRP1B

3.04e-0326592IPR026823
DomaincEGF

LTBP1 LRP1B

3.04e-0326592PF12662
DomainPkinase_C

RPS6KA4 PKN3

6.09e-0337592IPR017892
DomainSET

KMT2C NSD1

7.43e-0341592PF00856
DomainPkinase_C

RPS6KA4 PKN3

7.79e-0342592PF00433
DomainSET

KMT2C NSD1

9.29e-0346592SM00317
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

9.93e-14663520850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

9.93e-14663525930072
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A1 SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

6.86e-102463532212159
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NOP58 URB1 TSR1 CEBPZ NSD1 NUP188 ZBTB11 DDX24 SNRNP200 PPP6R3 KPNB1 XPO7

1.93e-09653631222586326
Pubmed

Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.

ACTA1 ACTA2 ACTC1

5.66e-0936337780165
Pubmed

Structural basis for regulation of protein phosphatase 1 by inhibitor-2.

PPP1R2 PPP1R2B PPP1R2P1

5.66e-09363317636256
Pubmed

Cloning and characterization of human phosphatase inhibitor-2 (IPP-2) sequences.

PPP1R2 PPP1R2B PPP1R2P1

2.26e-0846337949733
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PPP1R2 PPP3CB SLC4A1AP TSR1 CEBPZ ACTA1 PPP1R13B LTBP1 CIC RCAN3 LUZP1 PPP6R3 KPNB1

4.11e-081049631327880917
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KMT2C NOP58 CEBPZ NSD1 PPP1R13B SNRNP200 LUZP1 HTT PPP6R3 KPNB1

5.35e-08549631038280479
Pubmed

Regulators of the protein phosphatase PP1γ2, PPP1R2, PPP1R7, and PPP1R11 are involved in epididymal sperm maturation.

PPP1R2 PPP1R2B PPP1R2P1

5.65e-08563330144392
Pubmed

Protein Phosphatase-1 Inhibitor-2 Is a Novel Memory Suppressor.

PPP1R2 PPP1R2B PPP1R2P1

5.65e-08563326558779
Pubmed

Virus assembly and plasma membrane domains: which came first?

ACTA1 ACTA2 ACTC1

1.13e-07663322989508
Pubmed

HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.

ACTA1 ACTA2 ACTC1

1.13e-0766331540415
Pubmed

HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.

ACTA1 ACTA2 ACTC1

1.13e-07663311709093
Pubmed

Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.

ACTA1 ACTA2 ACTC1

1.13e-0766339971772
Pubmed

Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.

ACTA1 ACTA2 ACTC1

1.13e-07663310049817
Pubmed

Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.

ACTA1 ACTA2 ACTC1

1.13e-07663312009869
Pubmed

HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.

ACTA1 ACTA2 ACTC1

1.13e-07663323811015
Pubmed

Retroviral assembly and budding occur through an actin-driven mechanism.

ACTA1 ACTA2 ACTC1

1.13e-07663319883584
Pubmed

Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.

ACTA1 ACTA2 ACTC1

1.13e-07663321917091
Pubmed

HIV-1 Gag protein associates with F-actin present in microfilaments.

ACTA1 ACTA2 ACTC1

1.13e-0766338661406
Pubmed

A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.

ACTA1 ACTA2 ACTC1

1.13e-07663323017337
Pubmed

Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.

ACTA1 ACTA2 ACTC1

1.13e-07663310074138
Pubmed

Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.

ACTA1 ACTA2 ACTC1

1.13e-07663323875777
Pubmed

Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.

ACTA1 ACTA2 ACTC1

1.13e-0766339841925
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

NOP58 GNL3L RPS6KA4 FRMPD4 TSR1 CEBPZ ACTA1 ACTA2 ACTC1 SNRNP200 LUZP1 KPNB1

1.18e-07949631236574265
Pubmed

HIV-1 replication from after cell entry to the nuclear periphery.

ACTA1 ACTA2 ACTC1

1.97e-07763317504171
Pubmed

The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.

ACTA1 ACTA2 ACTC1

1.97e-07763322535526
Pubmed

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.

ACTA1 ACTA2 ACTC1

1.97e-07763322465675
Pubmed

Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.

ACTA1 ACTA2 ACTC1

1.97e-0776339384381
Pubmed

Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.

PPP1R2 PPP1R2B PPP1R2P1

1.97e-07763318689497
Pubmed

A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.

ACTA1 ACTA2 ACTC1

1.97e-07763330289203
Pubmed

Selective targeting of ITK blocks multiple steps of HIV replication.

ACTA1 ACTA2 ACTC1

1.97e-07763318443296
Pubmed

The trinity of the cortical actin in the initiation of HIV-1 infection.

ACTA1 ACTA2 ACTC1

1.97e-07763322640593
Pubmed

Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.

ACTA1 ACTA2 ACTC1

3.15e-07863314694110
Pubmed

Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis.

PPP1R2 PPP1R2B PPP1R2P1

3.15e-07863336693320
Pubmed

Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.

ACTA1 ACTA2 ACTC1

3.15e-07863320147394
Pubmed

Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.

ACTA1 ACTA2 ACTC1

3.15e-07863323260110
Pubmed

Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.

ACTA1 ACTA2 ACTC1

3.15e-07863320096780
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

SLC4A1AP ACTA1 ACTC1 WASHC2A SNRNP200 CIC PUS7 LUZP1 KPNB1

3.21e-0750663930890647
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

NOP58 URB1 GNL3L WASHC2C TSR1 CEBPZ GEMIN8 DDX24 SNRNP200 LUZP1 KPNB1

3.25e-07847631135850772
Pubmed

Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.

ACTA1 ACTA2 ACTC1

4.72e-07963312297046
Pubmed

Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.

ACTA1 ACTA2 ACTC1

4.72e-0796338892894
Pubmed

Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.

ACTA1 ACTA2 ACTC1

4.72e-07963310556093
Pubmed

HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.

ACTA1 ACTA2 ACTC1

4.72e-07963318775311
Pubmed

Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.

ACTA1 ACTA2 ACTC1

6.74e-071063321749862
Pubmed

Non-viral cellular substrates for human immunodeficiency virus type 1 protease.

ACTA1 ACTA2 ACTC1

6.74e-07106331991513
Pubmed

Gelsolin activity controls efficient early HIV-1 infection.

ACTA1 ACTA2 ACTC1

6.74e-071063323575248
Pubmed

Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.

ACTA1 ACTA2 ACTC1

6.74e-07106331907279
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

PPP1R2B GNL3L WASHC2C ACTA1 ZNF622 SNRNP200 CIC PKN3 PUS7 PPP6R3 KPNB1

8.51e-07934631133916271
Pubmed

CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.

ACTA1 ACTA2 ACTC1

9.25e-071163330962377
Pubmed

N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.

ACTA1 ACTA2 ACTC1

9.25e-071163323294842
Pubmed

Quantitative proteomic analysis of lentiviral vectors using 2-DE.

ACTA1 ACTA2 ACTC1

9.25e-071163319639585
Pubmed

FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity.

ACTA1 ACTA2 ACTC1

9.25e-071163322207710
Pubmed

HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.

ACTA1 ACTA2 ACTC1

1.23e-061263323071112
Pubmed

SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.

ACTA1 ACTA2 ACTC1

1.23e-061263331042497
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

NOP58 GNL3L SLC4A1AP TSR1 NSD1 ZBTB11 DDX24 CIC ZNF292

1.47e-0660863936089195
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

NOP58 URB1 GNL3L SLC4A1AP TSR1 CEBPZ ACTA1 ZBTB11 DDX24 SNRNP200 KPNB1

1.48e-06989631136424410
Pubmed

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice.

ACTA1 ACTA2 ACTC1

1.60e-061363318400219
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

PPP1R2 PPP3CB TSR1 ACTA1 ZNF622 NUP188 WASHC2A SNRNP200 PUS7 HTT PPP6R3 KPNB1 XPO7

1.69e-061455631322863883
Pubmed

LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.

ACTA1 ACTA2 ACTC1

2.03e-061463321923909
Pubmed

Regulating the functions of the HIV-1 matrix protein.

ACTA1 ACTA2 ACTC1

2.03e-061463317411366
Pubmed

Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance.

ACTA1 ACTA2 ACTC1

2.54e-061563324598388
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

NOP58 GNL3L TSR1 ACTA1 ACTA2 DDX24 SNRNP200 PKN3

2.71e-0648663830940648
Pubmed

Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose.

ACTA1 ACTA2 ACTC1

3.12e-061663316638982
Pubmed

Serum response factor is essential for mesoderm formation during mouse embryogenesis.

ACTA1 ACTA2 ACTC1

3.12e-06166339799237
Pubmed

Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin.

ACTA1 ACTC1

3.23e-06263219468071
Pubmed

Identification and characterization of two distinct PPP1R2 isoforms in human spermatozoa.

PPP1R2 PPP1R2B

3.23e-06263223506001
Pubmed

Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts.

ACTA1 ACTC1

3.23e-06263220706863
Pubmed

Identification of a novel Rev-interacting cellular protein.

WASHC2C WASHC2A

3.23e-06263215847701
Pubmed

alpha-Actin proteins and gene transcripts are colocalized in embryonic mouse muscle.

ACTA1 ACTC1

3.23e-0626321893870
Pubmed

Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer.

ACTA2 RBP4

3.23e-06263226927700
Pubmed

A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.

ACTA1 ACTC1

3.23e-0626323023046
Pubmed

Inhibition of the calcineurin-NFAT signalling cascade in the treatment of heart failure.

PPP3CB KPNB1

3.23e-06263219925438
Pubmed

Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).

WASHC2C WASHC2A

3.23e-06263220827171
Pubmed

Muscle specific expression of Cre recombinase under two actin promoters in transgenic mice.

ACTA2 ACTC1

3.23e-06263210686609
Pubmed

FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.

WASHC2C WASHC2A

3.23e-06263236717248
Pubmed

Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo.

ACTA1 ACTC1

3.23e-0626323075543
Pubmed

A developmental study of the abnormal expression of alpha-cardiac and alpha-skeletal actins in the striated muscle of a mutant mouse.

ACTA1 ACTC1

3.23e-0626322731651
Pubmed

A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA.

ACTA1 ACTC1

3.23e-0626326897014
Pubmed

Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.

ACTA1 ACTA2 ACTC1

3.78e-061763317360745
Pubmed

The cleavage of host cell proteins by HIV-1 protease.

ACTA1 ACTA2 ACTC1

3.78e-06176338997639
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KMT2C URB1 NSD1 NUP188 ZNF236 WASHC2A ABCA7 CIC PKN3 HTT BAHCC1

4.30e-061105631135748872
Pubmed

A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.

ACTA1 ACTA2 ACTC1

4.53e-061863324840128
Pubmed

Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets.

ACTA1 ACTA2 ACTC1

4.53e-061863315929941
Pubmed

Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice.

ACTA1 ACTA2 ACTC1

5.38e-061963330700554
Pubmed

Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.

ACTA1 ACTA2 ACTC1

5.38e-061963318316483
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

NOP58 URB1 CEBPZ ACTA2 ZNF622 WASHC2A DDX24 LUZP1 ZNF292

6.06e-0672463936232890
Pubmed

Protein phosphatase 1α interacting proteins in the human brain.

PPP1R2 FRMPD4 PPP1R13B ZBTB11

6.88e-066763422321011
Pubmed

Retinoic acid regulates differentiation of the secondary heart field and TGFbeta-mediated outflow tract septation.

ACTA1 ACTA2 ACTC1

7.36e-062163320230754
Pubmed

Myocardial Mycn is essential for mouse ventricular wall morphogenesis.

ACTA1 ACTA2 ACTC1

7.36e-062163323063798
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

KMT2C TSR1 GEMIN8 ACTA2 ACTC1 ZNF292 BAHCC1

7.77e-0639863735016035
Pubmed

Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression.

ACTA1 ACTA2 ACTC1

8.51e-062263316526095
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

NOP58 URB1 GNL3L TMEM183A CEBPZ ACTA2 ZNF622 NUP188 DDX24 SNRNP200 PPP6R3 KPNB1

9.13e-061440631230833792
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

NOP58 TSR1 CEBPZ ACTC1 ZNF622 ZBTB11 DDX24 SNRNP200 PPP6R3 KPNB1

9.19e-06971631033306668
Pubmed

Bmp2 regulates the interaction between EPDCs and myocytes in cardiac OFT.

ACTA1 ACTC1

9.68e-06363222647617
Pubmed

Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing.

ACTA1 ACTC1

9.68e-06363222855565
Pubmed

Actin and myosin genes are transcriptionally regulated during mouse skeletal muscle development.

ACTA1 ACTC1

9.68e-0636321728592
Pubmed

Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenes.

PPP1R2 PPP1R2B

9.68e-06363224195737
Pubmed

Crystal structure of the complex between actin and human vitamin D-binding protein at 2.5 A resolution.

ACTA1 ACTA2

9.68e-06363212119014
InteractionZNF330 interactions

NOP58 URB1 GNL3L SLC4A1AP TSR1 CEBPZ NSD1 ZNF622 NUP188 ZBTB11 DDX24 PUS7 ZNF292 XPO7

4.81e-114466114int:ZNF330
InteractionPOLR1G interactions

NOP58 URB1 GNL3L SLC4A1AP TSR1 CEBPZ NSD1 NUP188 ZBTB11 DDX24 CIC ZNF292 XPO7

1.96e-094896113int:POLR1G
InteractionSIRT7 interactions

NOP58 URB1 TSR1 CEBPZ NSD1 NUP188 ZBTB11 DDX24 SNRNP200 PPP6R3 KPNB1 XPO7

1.94e-067446112int:SIRT7
InteractionKPNB1 interactions

NOP58 TSR1 GLDC ASXL3 ACTC1 NUP188 SNRNP200 CIC HTT KPNB1

4.95e-065446110int:KPNB1
InteractionCOIL interactions

NOP58 URB1 CEBPZ NSD1 NUP188 ZBTB11 DDX24 SNRNP200 ZNF292 XPO7

5.63e-065526110int:COIL
InteractionRPL23AP32 interactions

URB1 CEBPZ NSD1 ZNF622 DDX24

6.57e-0687615int:RPL23AP32
InteractionRAE1 interactions

GNL3L NUP188 DDX24 CIC HTT KPNB1 XPO7

7.04e-06236617int:RAE1
InteractionDHX40 interactions

RNF7 URB1 CEBPZ NSD1 ACTC1 SNRNP200 PKN3

9.98e-06249617int:DHX40
InteractionRPS6 interactions

NOP58 URB1 GNL3L TSR1 CEBPZ PPP1R13B NUP188 ZBTB11 DDX24 CIC HTT KPNB1

1.01e-058746112int:RPS6
InteractionPOLR1E interactions

NOP58 URB1 CEBPZ NSD1 NUP188 ZBTB11 ZNF292 KPNB1

1.01e-05350618int:POLR1E
InteractionHNRNPU interactions

NOP58 GNL3L TSR1 CEBPZ GLDC ASXL3 ZNF622 USP4 DDX24 SNRNP200 CIC PKN3 KPNB1

1.06e-0510356113int:HNRNPU
InteractionWASHC4 interactions

RPS6KA4 WASHC2C WASHC2A SNRNP200 KPNB1

1.43e-05102615int:WASHC4
InteractionING1 interactions

WASHC2C ACTC1 CIC KPNB1 BAHCC1

1.50e-05103615int:ING1
InteractionNUP43 interactions

NOP58 GNL3L CEBPZ NSD1 ACTC1 ZBTB11 DDX24 SNRNP200 ZNF292 KPNB1

1.66e-056256110int:NUP43
InteractionREG3A interactions

ACTA2 ACTC1 PUS7

1.74e-0517613int:REG3A
InteractionPOTEJ interactions

ACTA1 ACTA2 ACTC1 DDX24

1.84e-0552614int:POTEJ
InteractionBRD7 interactions

NOP58 GNL3L TSR1 ACTA1 ACTA2 ACTC1 DDX24 SNRNP200 PKN3 KPNB1

1.95e-056376110int:BRD7
InteractionLARP7 interactions

NOP58 GNL3L TSR1 CEBPZ GLDC ACTA1 ACTA2 NSD1 ACTC1 USP4 ZBTB11 DDX24 KPNB1

2.28e-0511136113int:LARP7
InteractionRPS24 interactions

NOP58 URB1 GNL3L TSR1 CEBPZ ACTC1 NUP188 DDX24 CIC

2.85e-05529619int:RPS24
InteractionNMD3 interactions

RNF7 NOP58 GNL3L ZNF622 PUS7

3.14e-05120615int:NMD3
InteractionHAPSTR1 interactions

URB1 SLC4A1AP TSR1 FSIP1 ASXL3 ACTC1 DGKG USP4 NUP188 PPP6R3 KPNB1

3.40e-058296111int:HAPSTR1
InteractionGC interactions

RPS6KA4 ACTA1 ACTA2 ACTC1

3.72e-0562614int:GC
InteractionFZR1 interactions

GPRASP1 RNF7 NOP58 GNL3L TSR1 CEBPZ ACTC1 ZNF622 ZBTB11 DDX24 SNRNP200 PPP6R3 KPNB1

3.91e-0511726113int:FZR1
InteractionDYRK1A interactions

MYT1L PPP1R2 GEMIN8 ZBTB11 LRP1B CIC LUZP1 KPNB1 XPO7

3.97e-05552619int:DYRK1A
InteractionACTC1 interactions

SLC4A1AP ACTA1 ACTA2 ACTC1 WASHC2A SNRNP200 CIC PUS7 LUZP1 KPNB1

4.05e-056946110int:ACTC1
InteractionLIMA1 interactions

GLDC ACTA1 ACTA2 ACTC1 USP4 DDX24 CIC LUZP1

4.33e-05429618int:LIMA1
InteractionNIFK interactions

NOP58 URB1 GNL3L CEBPZ NSD1 NUP188 ZBTB11 DDX24

4.48e-05431618int:NIFK
InteractionNUP153 interactions

NOP58 TSR1 ACTC1 NUP188 KPNB1 XPO7

4.80e-05216616int:NUP153
InteractionMEN1 interactions

KMT2C NOP58 URB1 GNL3L WASHC2C TSR1 CEBPZ GEMIN8 NUP188 DDX24 SNRNP200 LUZP1

5.04e-0510296112int:MEN1
InteractionNOP56 interactions

NOP58 URB1 GNL3L TSR1 CEBPZ ACTA2 NSD1 DDX24 KPNB1

5.09e-05570619int:NOP56
InteractionRUVBL1 interactions

NOP58 TSR1 ASXL3 ACTC1 SNRNP200 CIC HTT PPP6R3 KPNB1

5.44e-05575619int:RUVBL1
InteractionNOP14 interactions

NOP58 TSR1 CEBPZ GLDC DGKG DDX24

5.59e-05222616int:NOP14
InteractionDUSP10 interactions

ACTA2 ACTC1 HTT PPP6R3

6.34e-0571614int:DUSP10
InteractionPPP1CB interactions

PPP1R2 PPP1R2B GNL3L ACTA1 PPP1R13B DDX24 LUZP1 KPNB1

8.09e-05469618int:PPP1CB
InteractionTNNI3 interactions

ACTA1 ACTA2 RCAN3

8.19e-0528613int:TNNI3
InteractionRPL4 interactions

NOP58 URB1 CEBPZ GLDC NSD1 ZBTB11 DDX24 SNRNP200 CIC HTT

9.05e-057646110int:RPL4
InteractionTMSB4X interactions

ACTA1 ACTA2 ACTC1 PKN3

1.01e-0480614int:TMSB4X
InteractionADARB1 interactions

URB1 TSR1 CEBPZ ACTA1 ACTA2 ACTC1 ZBTB11 DDX24

1.08e-04489618int:ADARB1
InteractionPPP1R11 interactions

PPP1R2 PPP3CB PPP1R13B

1.12e-0431613int:PPP1R11
InteractionCAPZA1 interactions

WASHC2C ASXL3 ACTC1 USP4 WASHC2A CIC HTT

1.16e-04366617int:CAPZA1
InteractionSPTAN1 interactions

GLDC ACTA1 ACTA2 ACTC1 NUP188 WASHC2A DDX24 HTT

1.19e-04496618int:SPTAN1
InteractionNOPCHAP1 interactions

NOP58 WASHC2C KPNB1

1.23e-0432613int:NOPCHAP1
InteractionDHX15 interactions

RNF7 NOP58 GLDC ACTC1 SNRNP200 CIC PUS7 HTT

1.30e-04502618int:DHX15
InteractionCENPA interactions

URB1 TSR1 CEBPZ NSD1 NUP188 DDX24 ZNF292

1.39e-04377617int:CENPA
InteractionDOT1L interactions

NOP58 URB1 GNL3L TSR1 CEBPZ GEMIN8 DDX24 SNRNP200 LUZP1 KPNB1

1.42e-048076110int:DOT1L
InteractionH1-4 interactions

CEBPZ GLDC ASXL3 NSD1 ACTC1 ZBTB11 DDX24 HTT KPNB1

1.48e-04656619int:H1-4
InteractionNAA40 interactions

PPP1R2B GNL3L WASHC2C ACTA1 ZNF622 SNRNP200 CIC PKN3 PUS7 PPP6R3 KPNB1

1.49e-049786111int:NAA40
InteractionPHAX interactions

TSR1 GEMIN8 ACTC1 SNRNP200 KPNB1

1.50e-04167615int:PHAX
InteractionRPLP0 interactions

URB1 CEBPZ ACTC1 USP4 ZBTB11 WASHC2A DDX24 CIC HTT

1.55e-04660619int:RPLP0
InteractionWASHC5 interactions

WASHC2C ACTC1 WASHC2A PPP6R3

1.60e-0490614int:WASHC5
InteractionH1-2 interactions

URB1 SLC4A1AP CEBPZ ASXL3 NSD1 DDX24 HTT KPNB1 SP140

1.66e-04666619int:H1-2
InteractionALB interactions

ASXL3 SPATA31A7 RBP4 DGKG DDX24 CIC ZNF292

1.74e-04391617int:ALB
InteractionGNL1 interactions

NOP58 HTT PPP6R3 KPNB1

1.74e-0492614int:GNL1
InteractionABRA interactions

ACTA1 ACTA2 ACTC1

1.75e-0436613int:ABRA
InteractionDNASE1 interactions

ACTA1 ACTA2

1.87e-047612int:DNASE1
InteractionWASHC1 interactions

WASHC2C ACTA1 ACTA2 WASHC2A

1.89e-0494614int:WASHC1
InteractionRPL31 interactions

NOP58 URB1 GNL3L TSR1 CEBPZ NSD1 NUP188 ZBTB11 DDX24

1.94e-04680619int:RPL31
InteractionZNF467 interactions

URB1 GNL3L CEBPZ NSD1 DDX24

2.08e-04179615int:ZNF467
InteractionPFKP interactions

USP4 CIC PKN3 HTT PPP6R3 KPNB1

2.15e-04284616int:PFKP
InteractionPPP3CB interactions

PPP1R2 PPP3CB PPP1R13B RCAN3

2.22e-0498614int:PPP3CB
InteractionPPP1CA interactions

PPP1R2 PPP1R2B FRMPD4 ACTA1 PPP1R13B ZBTB11 CIC HTT KPNB1

2.31e-04696619int:PPP1CA
InteractionRPL10 interactions

NOP58 GNL3L TSR1 ACTC1 ZNF622 ZBTB11 DDX24 LRP1B PPP6R3

2.46e-04702619int:RPL10
InteractionTNIP1 interactions

NOP58 GNL3L RPS6KA4 FRMPD4 TSR1 CEBPZ ACTA1 ACTA2 ACTC1 SNRNP200 LUZP1 KPNB1

2.46e-0412176112int:TNIP1
InteractionTERF2IP interactions

PPP1R2 SLC4A1AP NSD1 DDX24 CIC PUS7 PPP6R3 ZNF292

2.47e-04552618int:TERF2IP
InteractionWWTR1 interactions

NOP58 CEBPZ PPP1R13B LUZP1 HTT PPP6R3 KPNB1

2.77e-04422617int:WWTR1
InteractionZNF692 interactions

CEBPZ NSD1 DDX24

2.78e-0442613int:ZNF692
InteractionDDX21 interactions

URB1 TSR1 CEBPZ GLDC ACTC1 DDX24 SNRNP200 CIC KPNB1

2.90e-04718619int:DDX21
InteractionFASN interactions

KMT2C GLDC ASXL3 ACTC1 ZNF622 USP4 LTBP1 NUP188 ZNF236 HTT ZNF292

3.05e-0410626111int:FASN
InteractionPLEC interactions

GLDC ACTA1 ACTA2 ACTC1 USP4 LUZP1 HTT

3.10e-04430617int:PLEC
InteractionCAPZA2 interactions

WASHC2C ASXL3 ACTA1 ACTC1 WASHC2A LUZP1 HTT

3.10e-04430617int:CAPZA2
InteractionERRFI1 interactions

ACTA1 ACTA2 ACTC1 PUS7

3.11e-04107614int:ERRFI1
InteractionH2AB2 interactions

URB1 CEBPZ ZBTB11 DDX24

3.11e-04107614int:H2AB2
InteractionPPP1R7 interactions

PPP1R2 PPP3CB ACTA1 PPP1R13B

3.57e-04111614int:PPP1R7
InteractionADISSP interactions

PPP1R2 PPP3CB PPP1R13B

3.65e-0446613int:ADISSP
InteractionANGPTL8 interactions

ACTA1 ACTA2

3.99e-0410612int:ANGPTL8
InteractionPFN3 interactions

ACTA2 ACTC1

3.99e-0410612int:PFN3
InteractionZBTB2 interactions

NOP58 GNL3L CEBPZ DDX24 SNRNP200 PUS7 KPNB1

4.07e-04450617int:ZBTB2
InteractionCHD3 interactions

NOP58 TSR1 CEBPZ ACTC1 ZNF622 DDX24 SNRNP200 HTT KPNB1

4.28e-04757619int:CHD3
InteractionACTG2 interactions

ACTA1 ACTA2 ACTC1

4.40e-0449613int:ACTG2
InteractionNOLC1 interactions

NOP58 GNL3L CEBPZ ACTC1 USP4 KPNB1

4.42e-04325616int:NOLC1
InteractionGSN interactions

ACTA1 ACTA2 ACTC1 HTT BAHCC1

4.53e-04212615int:GSN
InteractionZMAT2 interactions

ACTC1 USP4 SNRNP200 HTT

4.65e-04119614int:ZMAT2
InteractionWASH8P interactions

ACTA2 ACTC1

4.87e-0411612int:WASH8P
InteractionGSK3A interactions

PPP1R2 PPP1R2B PPP3CB TSR1 WASHC2A LUZP1 PPP6R3

4.89e-04464617int:GSK3A
InteractionWASHC2A interactions

WASHC2C ACTC1 WASHC2A PPP6R3

5.11e-04122614int:WASHC2A
InteractionCSNK2A1 interactions

PPP1R2 RNF7 NOP58 SLC4A1AP TSR1 ASXL3 DDX24 CIC HTT KPNB1

5.49e-049566110int:CSNK2A1
InteractionHSP90AB1 interactions

KMT2C RPS6KA4 WASHC2C GLDC ASXL3 DDX24 CIC PKN3 HTT PPP6R3

5.67e-049606110int:HSP90AB1
InteractionRSL1D1 interactions

NOP58 GLDC NSD1 ZBTB11 DDX24 PPP6R3 KPNB1

5.91e-04479617int:RSL1D1
InteractionHNRNPC interactions

TSR1 GLDC DDX24 SNRNP200 CIC HTT PPP6R3 KPNB1

6.22e-04634618int:HNRNPC
InteractionSNRNP40 interactions

NOP58 URB1 SLC4A1AP CEBPZ ACTC1 ZBTB11 DDX24 SNRNP200

6.41e-04637618int:SNRNP40
InteractionFBL interactions

NOP58 URB1 TSR1 CEBPZ NUP188 DDX24 CIC PUS7

6.54e-04639618int:FBL
InteractionGAR1 interactions

TSR1 CEBPZ NSD1 CIC PUS7

6.82e-04232615int:GAR1
InteractionBUB3 interactions

KMT2C ASXL3 ACTA2 CIC KPNB1

6.82e-04232615int:BUB3
InteractionPPP1R1A interactions

ACTA1 ACTA2

6.88e-0413612int:PPP1R1A
InteractionPCYT1B interactions

ACTA1 ACTA2

6.88e-0413612int:PCYT1B
InteractionSNORD3A interactions

NOP58 NSD1

6.88e-0413612int:SNORD3A
InteractionSUZ12 interactions

NOP58 TSR1 GLDC ACTC1 KIAA1958 SNRNP200 HTT KPNB1

6.88e-04644618int:SUZ12
InteractionH3C3 interactions

NOP58 GNL3L TSR1 NSD1 DDX24 CIC ZNF292

7.17e-04495617int:H3C3
InteractionSCIN interactions

ACTA1 ACTA2 ACTC1

7.23e-0458613int:SCIN
InteractionMAGEA3 interactions

PPP3CB ACTC1 HTT KPNB1

7.27e-04134614int:MAGEA3
CytobandEnsembl 112 genes in cytogenetic band chr9q12

SPATA31A7 SPATA31A5

5.16e-058632chr9q12
Cytoband9p13.1

SPATA31A1 SPATA31A3

5.02e-04246329p13.1
CytobandXp22.2

FRMPD4 GEMIN8

1.40e-0340632Xp22.2
Cytoband15q14

FSIP1 ACTC1

2.09e-034963215q14
Cytoband9q34.11

NUP188 PKN3

2.44e-03536329q34.11
CytobandEnsembl 112 genes in cytogenetic band chr15q14

FSIP1 ACTC1

3.22e-0361632chr15q14
GeneFamilyActins

ACTA1 ACTA2 ACTC1

1.85e-076393929
GeneFamilyWASH complex

WASHC2C WASHC2A

6.76e-0563921331
GeneFamilyPHD finger proteins

KMT2C NSD1 SP140

9.58e-049039388
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2C NSD1

2.44e-0334392487
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

GPRASP1 KPNB1

3.87e-0343392409
CoexpressionLEE_CALORIE_RESTRICTION_MUSCLE_UP

PPP1R2 PPP1R2B ACTC1 PPP1R2P1

3.06e-0643614MM669
CoexpressionLEE_AGING_MUSCLE_DN

PPP1R2 PPP1R2B PPP1R2P1 USP4

4.03e-0646614MM670
CoexpressionAPRELIKOVA_BRCA1_TARGETS

ACTA1 ACTA2 ACTC1 DDX24

4.78e-0648614M1568
CoexpressionAPRELIKOVA_BRCA1_TARGETS

ACTA1 ACTA2 ACTC1 DDX24

5.20e-0649614MM1178
CoexpressionTABULA_MURIS_SENIS_LIMB_MUSCLE_B_CELL_AGEING

PPP1R2 PPP1R2B NOP58 PPP1R2P1 DDX24 SP140

1.63e-05231616MM3741
CoexpressionGSE27786_CD8_TCELL_VS_NEUTROPHIL_UP

CEBPZ ZNF622 DDX24 SNRNP200 PUS7

1.01e-04199615M4846
CoexpressionGSE46143_CTRL_VS_LMP2A_TRANSDUCED_CD10_POS_GC_BCELL_UP

TSR1 RBP4 NSD1 PPP1R2P1 HTT

1.03e-04200615M9771
CoexpressionRAMALHO_STEMNESS_UP

PPP1R2 PPP1R2B NOP58 TMEM183A PPP1R2P1

1.11e-04203615MM1017
CoexpressionSHEPARD_CRASH_AND_BURN_MUTANT_UP

TSR1 RBP4 ZNF622 GCNT4 CIC

1.16e-04205615M10828
CoexpressionBURTON_ADIPOGENESIS_PEAK_AT_8HR

PPP1R2 PPP1R2B PPP1R2P1

1.29e-0442613MM691
CoexpressionVANASSE_BCL2_TARGETS_UP

PPP1R2 PPP1R2B PPP1R2P1

1.39e-0443613MM799
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5

PPP1R2B NOP58 CEBPZ GLDC LUZP1 KPNB1

2.37e-05204606Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#4_top-relative-expression-ranked_100

ACTA1 ACTA2 ACTC1

5.32e-0526603gudmap_developingLowerUrinaryTract_P1_bladder_J_100_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#3_top-relative-expression-ranked_100

ACTA1 ACTA2 ACTC1

6.68e-0528603gudmap_developingLowerUrinaryTract_P1_bladder_B_100_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_k-means-cluster#4_top-relative-expression-ranked_200

ACTA1 ACTA2 RBP4

9.11e-0531603gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_200_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#1_top-relative-expression-ranked_500

ACTA1 ACTA2 RBP4 ACTC1

1.03e-0486604gudmap_developingLowerUrinaryTract_P1_ureter_500_k1
ToppCellStriatum-Neuronal|Striatum / BrainAtlas - Mouse McCarroll V32

MYT1L GPRASP1 GNL3L PPP3CB FRMPD4 DDX24

3.58e-07200626c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

GPRASP1 PADI4 NOP58 DDX24 RCAN3

4.94e-0617862573936c2e7e8855b4ab65cad425686513dba331a3
ToppCellPericytes|World / shred by cell class for parenchyma

ACTA1 ACTA2 ACTC1 DGKG LTBP1

7.89e-061966258e7ecbe77d312a7fc6aadd8fd52c13dd1834cc7e
ToppCell(5)_Fibroblast-K_(Pericytes)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ACTA1 ACTA2 ACTC1 DGKG LTBP1

7.89e-06196625e3c89c5bd674289738d5590ebfd30c605f5156a5
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA1 ACTA2 ACTC1 DGKG LTBP1

7.89e-0619662570b2e0b4ff4f1bc03fb72ace07a8a44f4b415922
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA1 ACTA2 ACTC1 DGKG LTBP1

7.89e-06196625ac4c8571bd792538f8df7b9bdd90ef58405fd3b1
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ELAPOR2 ACTA1 ACTA2 DGKG LTBP1

8.28e-061986251e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ACTA1 ACTA2 ACTC1 DGKG LTBP1

8.49e-06199625534dcfe8b65ad92bb8d749d1c7036ad4807e09cd
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GPRASP1 ELAPOR2 NOP58 ZNF236

6.31e-05154624ec920cae12ea1d14b6c973f6e903f895f80e3c50
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

ACTA2 DGKG LTBP1 GCNT4

7.50e-0516162464891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PPP3CB CD163L1 ACTA2 CIC

8.84e-051686248459d0a1bf6d4b5c83001097331f8b78fceb9305
ToppCellPericytes-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

MYT1L GLDC ACTA2 LTBP1

9.46e-05171624bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

ACTA2 ACTC1 LTBP1 LRP1B

1.03e-04175624fed9e4120c758fdcc23bb248d1801002b0e0d485
ToppCellPericytes-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

ACTA2 ACTC1 DGKG LTBP1

1.03e-04175624ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCellCOPD-Stromal-SMC|World / Disease state, Lineage and Cell class

ACTA2 ACTC1 DGKG LTBP1

1.13e-04179624b2709537ec1b46457ab85261f4cdd354e60a8b29
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ACTA1 ACTC1 DGKG LTBP1

1.18e-04181624719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRMPD4 ACTA2 ACTC1 LTBP1

1.20e-0418262437547b36264090b49a193a8ef3a8d88e647f0b79
ToppCellPericytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

ACTA1 ACTA2 ACTC1 LTBP1

1.23e-04183624d04deef7cd4e1738227a6593b84874ce0168c773
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

ACTA1 ACTC1 DGKG LTBP1

1.25e-04184624ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ACTA1 ACTC1 DGKG LTBP1

1.28e-04185624549eeb521c3985bff396ea0f202db21822efa51f
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRMPD4 LTBP1 LRP1B PKN3

1.31e-041866242d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRMPD4 LTBP1 LRP1B PKN3

1.31e-0418662492092f11ecce22c14f244e42c499af0822977e6f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACTA2 ACTC1 DGKG LTBP1

1.31e-041866244780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-VSMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ACTA2 ACTC1 DGKG LTBP1

1.31e-04186624c7885fd6dc7dc8fffc96f0112c51a365cf8a8f80
ToppCellPericytes-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ACTA2 ACTC1 DGKG LTBP1

1.34e-0418762435f25780d113f60bf4c13749013c09612ee4ff41
ToppCellIPF-Stromal-SMC|World / Disease state, Lineage and Cell class

ACTA2 ACTC1 DGKG LTBP1

1.36e-04188624b66264e8f8d536ed2beec31e6746c687718f239b
ToppCellIPF-Stromal-SMC|IPF / Disease state, Lineage and Cell class

ACTA2 ACTC1 DGKG LTBP1

1.36e-04188624e98b24c0de41285f01f7ac194ff0a1b59fd5c333
ToppCellCOVID-19-kidney-vSMC/Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

ACTA2 ACTC1 DGKG LTBP1

1.45e-04191624fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA1 ACTA2 ACTC1 LTBP1

1.45e-041916242a107e9096eb58b81b3da61547904d85754f6b2f
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA1 ACTA2 ACTC1 LTBP1

1.45e-04191624d35692c652977500a3c36aa26c347a072b71e441
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRMPD4 ACTA2 ACTC1 LTBP1

1.51e-041936244aa976b596830b585e8d9c808d5072ed23d13a7c
ToppCellThalamus-Neuronal|Thalamus / BrainAtlas - Mouse McCarroll V32

MYT1L GPRASP1 PPP3CB FRMPD4

1.51e-04193624712a4acd1167e43543950bc819ff11984e6f718d
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ACTA1 ACTA2 ACTC1 DGKG

1.51e-041936245ec917931b438dd0e7fb03eb6af459d3ef6b84ba
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ACTA1 ACTA2 ACTC1 DGKG

1.51e-041936245260ac95a15cc43a19909badad0c7e3854da920d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

GPRASP1 GCNT4 DDX24 RCAN3

1.51e-041936244e78ddc96d8e403a21c4a303b1f26512d2ac91e8
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYT1L GPRASP1 GNL3L DDX24

1.54e-041946248aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACTA2 ACTC1 DGKG LTBP1

1.57e-0419562426a3a5daf389606ef1ebb35533f12e60853b3a12
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_memory_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PPP1R2 GCNT4 DDX24 RCAN3

1.60e-04196624b10810c6a2ad3d3b968bfef46a68a38e0ce31331
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PPP1R2 NOP58 FSIP1 CEBPZ

1.60e-04196624ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA2 ACTC1 DGKG LTBP1

1.60e-04196624208ddedd29e1b9ca89cbb9b527c2e193a44cada2
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACTA2 DGKG LTBP1 LRP1B

1.60e-041966249830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell(5)_Fibroblasts-(5)_Fibroblast-K_(Pericytes)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

ACTA1 ACTA2 ACTC1 DGKG

1.60e-04196624541b1fcf509e362f6f48720046cb5378aaf7c591
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KMT2C DDX24 SNRNP200 ZNF292

1.63e-0419762457ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACTA2 ACTC1 DGKG LTBP1

1.63e-04197624d16bb765afdc02406ffd7ce6a75bae72b66db66c
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)|343B / Donor, Lineage, Cell class and subclass (all cells)

ACTA1 ACTA2 ACTC1 LTBP1

1.63e-0419762478d45d11820ec379942c4c3defd619d5f8cc8e1f
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ACTA1 ACTA2 ACTC1 LTBP1

1.63e-0419762431bc9fd679d78550541d4158568e8dd09ff29e8e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACTA1 ACTA2 ACTC1 DGKG

1.63e-04197624b7e399b8e1a1ffc2b359f14929f199b93d9bbcce
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GLDC ACTA2 DGKG LTBP1

1.66e-04198624d1827e3707b929e3a3562989a0c11537d344e164
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACTA2 ACTC1 DGKG LTBP1

1.66e-041986247dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACTA2 DGKG LTBP1 LRP1B

1.66e-0419862422e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)|390C / Donor, Lineage, Cell class and subclass (all cells)

ACTA1 ACTA2 ACTC1 LTBP1

1.66e-04198624c82a151f9f1477d4a401457173b8d72af776c137
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)-|390C / Donor, Lineage, Cell class and subclass (all cells)

ACTA1 ACTA2 ACTC1 LTBP1

1.66e-04198624dc63b56bb6291e527b172d603569376286262845
ToppCellCaecum-T_cell-Tfh|Caecum / Region, Cell class and subclass

GNL3L LTBP1 GCNT4 PKN3

1.69e-04199624fb40f37d842f170ed101dfa3bffdb8f3b2c94f19
ToppCellParenchyma_COVID-19-Stromal-TX-Smooth_muscle-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ACTA2 ACTC1 DGKG LTBP1

1.69e-04199624c8bc05dece8b8a87d4a7a3e8112b924e15217de1
ToppCellcontrol-unassigned|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PADI4 FSIP1 ACTA2 PPP1R13B

1.69e-041996245db7c8089172ac8e796613b3cef618d87007a0ab
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

NOP58 CEBPZ DDX24 SP140

1.69e-04199624952fac67588ad5676f5939e3c7f8bac803c27064
ToppCellCaecum-(1)_T_cell-(16)_Tfh|Caecum / shred on region, Cell_type, and subtype

GNL3L LTBP1 GCNT4 PKN3

1.69e-04199624d07d77ae426dd1164d80d7031f14befa0369d3e5
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ACTA2 ACTC1 DGKG LTBP1

1.69e-04199624c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOP58 CEBPZ DDX24 RCAN3

1.69e-041996243003badee037d4d63a8018a74c0aea213d049e43
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ACTA2 ACTC1 DGKG LTBP1

1.69e-041996248ff0fdcbe9661b013913731ec8b53d84836ca865
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYT1L GPRASP1 PPP3CB DDX24

1.69e-04199624f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ACTA2 ACTC1 DGKG LTBP1

1.69e-0419962478b245d40c1e169ff2d26907b63d732e34529c5f
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ACTA2 ACTC1 DGKG LTBP1

1.69e-041996248e1e95c3a4b856415af208be6ad977e575bac189
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ACTA1 ACTA2 ACTC1 LTBP1

1.73e-042006242bc7f462a551292de2501028164573935232f899
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ACTA2 ACTC1 DGKG LTBP1

1.73e-042006249169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellproximal-3-mesenchymal-Airway_Smooth_Muscle|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ACTA2 ACTC1 DGKG LTBP1

1.73e-04200624e9a008bfe336002218c63d1c2231986e1b237621
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal|10w / Sample Type, Dataset, Time_group, and Cell type.

NOP58 CD163L1 ACTA1 ZNF622

1.73e-04200624c968d077b7fd24fb06cedb51c737996f25667eb7
ToppCellproximal-mesenchymal-Airway_Smooth_Muscle|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ACTA2 ACTC1 DGKG LTBP1

1.73e-042006245eeb8eb3fe74f5a8055c52ec77e38237bb63ed90
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ACTA2 ACTC1 DGKG LTBP1

1.73e-04200624f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ACTA2 ACTC1 DGKG LTBP1

1.73e-04200624a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACTA2 ACTC1 DGKG LTBP1

1.73e-04200624a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3|Control_saline / Treatment groups by lineage, cell group, cell type

ACTA2 ACTC1 DGKG LTBP1

1.73e-04200624b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCellproximal-mesenchymal-Airway_Smooth_Muscle-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ACTA2 ACTC1 DGKG LTBP1

1.73e-042006246fa339666c4032b29ac521e88f0e917a57013cde
ToppCelldistal-3-mesenchymal-Airway_Smooth_Muscle|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ACTA2 ACTC1 DGKG LTBP1

1.73e-042006244072cfb3047954f507289587b4bfaf1526936992
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_only / Treatment groups by lineage, cell group, cell type

ACTA2 ACTC1 DGKG LTBP1

1.73e-042006247c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ACTA1 ACTA2 ACTC1 LTBP1

1.73e-042006248b80a65b69b36ed405214564b939452c90aa40d6
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

GNL3L RPS6KA4 PPP3CB TSR1 CIC PUS7 KPNB1

5.30e-071905871612_DN
DrugAmphotericin B [1397-89-3]; Down 200; 4.4uM; HL60; HT_HG-U133A

PADI4 URB1 RPS6KA4 DGKG ABCA7 RCAN3

1.05e-051965862441_DN
DrugNsc687160

ACTA1 ACTA2 ACTC1

1.25e-0518583CID005459290
Drugtolytoxin

ACTA1 ACTA2 ACTC1

1.48e-0519583CID006440827
Drugm2-19

ACTA1 ACTA2 ACTC1

1.48e-0519583CID000079129
DrugAC1L8NVR

ACTA1 ACTA2 ACTC1

2.02e-0521583CID000384633
DrugNSC312786

ACTA1 ACTA2 ACTC1

2.02e-0521583CID000329495
DrugAC1L1ERT

ACTA1 ACTA2 ACTC1 PKN3

2.90e-0569584CID000002920
DrugCID5288653

ACTA1 ACTA2 ACTC1

4.91e-0528583CID005288653
Drugazaspiracid

ACTA1 ACTA2 ACTC1

6.07e-0530583CID006451158
DrugD-myo-inositol 1,4-bisphosphate

ACTA1 ACTA2 ACTC1 PKN3

6.89e-0586584CID000000805
DrugAC1L1HS4

ACTA1 ACTA2 ACTC1

7.38e-0532583CID000004267
DrugAC1L1BDQ

ACTA1 ACTA2 ACTC1 DGKG PKN3

7.91e-05173585CID000001394
DrugN,N'-p-phenylenedimaleimide

ACTA1 ACTA2 ACTC1

8.88e-0534583CID000076765
Drug1,N6-ethenoadenosine 5'-diphosphate

ACTA1 ACTA2 ACTC1

8.88e-0534583CID000001312
DrugPergolide mesylate [66104-23-2]; Down 200; 9.8uM; HL60; HT_HG-U133A

URB1 PPP3CB TSR1 PUS7 BAHCC1

9.79e-051815852403_DN
DrugAC1NSKFN

ACTA1 ACTA2 ACTC1

1.06e-0436583CID005311324
DrugAstemizole [68844-77-9]; Down 200; 8.8uM; HL60; HG-U133A

PADI4 URB1 GNL3L RPS6KA4 ZNF236

1.29e-041925851365_DN
DrugFenoterol hydrobromide [1944-12-3]; Down 200; 10.4uM; HL60; HT_HG-U133A

URB1 GNL3L TSR1 PUS7 BAHCC1

1.29e-041925852378_DN
Drugradicicol, diheterospora chlamydosporia; Down 200; 0.1uM; HL60; HT_HG-U133A

URB1 RPS6KA4 CIC PUS7 BAHCC1

1.39e-041955851160_DN
DrugEthisterone [434-03-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A

GPRASP1 LTBP1 LUZP1 PPP6R3 ZNF292

1.39e-041955853864_DN
Drugetheno-NAD

PADI4 ACTA1 ACTA2 ACTC1

1.44e-04104584CID005288160
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

PADI4 URB1 RPS6KA4 PUS7 HTT

1.46e-041975852375_DN
DrugEstrone [53-16-7]; Down 200; 14.8uM; HL60; HT_HG-U133A

NSD1 DGKG RCAN3 BAHCC1 SP140

1.46e-041975853071_DN
Drugepsilon-ATP

ACTA1 ACTA2 ACTC1

1.56e-0441583CID000162262
DrugBenzocaine [94-09-7]; Up 200; 24.2uM; HL60; HT_HG-U133A

BNC1 ACTA2 NUP188 SNRNP200 SP140

1.56e-042005852167_UP
DrugBeta-sistosterol [83-46-5]; Up 200; 9.6uM; HL60; HT_HG-U133A

NUP188 ABCA7 RCAN3 BAHCC1 SP140

1.56e-042005852912_UP
DrugAC1OAGGW

ACTA1 ACTA2 ACTC1 DGKG PKN3

1.67e-04203585CID006857364
DiseaseIntellectual Disability

MYT1L KMT2C FRMPD4 NSD1 ZBTB11 CIC PUS7 HTT ZNF292

1.56e-07447569C3714756
Diseaseautosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

3.60e-078563DOID:0110550 (implicated_via_orthology)
DiseaseBaraitser-Winter syndrome 1 (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

3.60e-078563DOID:0081112 (implicated_via_orthology)
DiseaseMoyamoya disease (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

3.60e-078563DOID:13099 (implicated_via_orthology)
Diseasethoracic aortic aneurysm (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

3.60e-078563DOID:14004 (implicated_via_orthology)
Diseaseintestinal atresia (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

7.70e-0710563DOID:10486 (implicated_via_orthology)
Diseasepatent ductus arteriosus (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

7.70e-0710563DOID:13832 (implicated_via_orthology)
DiseaseNeurodevelopmental Disorders

MYT1L KMT2C ASXL3 ZNF292

3.00e-0593564C1535926
Diseasewhite matter volume measurement

LRP1B CIC ZNF292

3.09e-0532563EFO_0008320
Diseasefemoral neck bone geometry

NSD1 PPP6R3

3.17e-0414562EFO_0004511
DiseaseAttention deficit hyperactivity disorder

CIC ZNF292

9.51e-0424562C1263846
Diseaseneutrophil count

WASHC2C NSD1 DGKG PPP1R2P1 ABCA7 CIC PKN3 HTT ZNF292

1.10e-031382569EFO_0004833
Diseasecaudate nucleus volume

MYT1L KIAA1958

1.49e-0330562EFO_0004830
Diseaseapolipoprotein B measurement

NOP58 SLC4A1AP GCNT4 PKN3 HTT KPNB1

1.57e-03663566EFO_0004615

Protein segments in the cluster

PeptideGeneStartEntry
DELGQQSMEDSEEDC

BAHCC1

1261

Q9P281
MCDEDETTALVCDNG

ACTA1

1

P68133
EEGTVLMEDSDGNCE

BNC1

881

Q01954
MCEEEDSTALVCDNG

ACTA2

1

P62736
EDVGVICSDASDMEL

CD163L1

676

Q9NR16
SDIETAADKCEEMEE

PPP1R13B

986

Q96KQ4
LVCESELDGTDMAEA

ASXL3

96

Q9C0F0
VVEECAADTDMEDGS

ABCA7

1146

Q8IZY2
MADVEDGEETCALAS

RNF7

1

Q9UBF6
LCSTDQEEEEEMIFG

RCAN3

16

Q9UKA8
FTCVDDADVDSEMDP

NSD1

156

Q96L73
SSAMDCEDDEVLDSE

PADI4

161

Q9UM07
AAAEISMGTEVSEED

NOP58

236

Q9Y2X3
EEVENVADIGFDCSM

KMT2C

1121

Q8NEZ4
DGSDEMDCVTECKED

LRP1B

3621

Q9NZR2
EMETESDAEVECDLS

GEMIN8

121

Q9NWZ8
HSTMGDDEDACSDTE

PPP1R2P1

76

Q96PQ5
DDEDACSDTETTEAM

PPP1R2P1

81

Q96PQ5
ETEENIEGEMSSEDC

KIAA1109

306

Q2LD37
FMASEEGTNCIDVDE

LTBP1

946

Q14766
MGDEDDDESCAVELR

RPS6KA4

1

O75676
AADSCAIMEGEDNEE

ELAPOR2

976

A8MWY0
DDEDACSDTEATEAM

PPP1R2

81

P41236
ADEACAPDTESNMAE

DGKG

116

P49619
SDDAESDVRMVADEC

HTT

136

P42858
IDLEDDDVVAMTSDC

GCNT4

96

Q9P109
EDEVSCEEDLVVGEM

FRMPD4

751

Q14CM0
SASMEEEGEDCTLSV

LUZP1

1021

Q86V48
VCDEEMDLAIEASEA

KPNB1

286

Q14974
DGQMDDLVCFEELTD

DDX24

41

Q9GZR7
EDADMLESEECEASK

FSIP1

466

Q8NA03
CSDDELMTEGEDQFD

PPP3CB

381

P16298
VSLGSMDDEEFAEVD

CEBPZ

901

Q03701
GDTEEEVFDCIVNMD

PKN3

761

Q6P5Z2
AETSCDTMQGAEEEE

GPRASP1

596

Q5JY77
ATCESGAGSEVEVDM

SPATA31A6

841

Q5VVP1
DIEDTEQANEDTMEC

GNL3L

426

Q9NVN8
TCESGAGSEVEVDMF

SPATA31A7

846

Q8IWB4
EECEEEESESFADMM

PUS7

91

Q96PZ0
MVCEAADDAPSSEEE

URB1

2241

O60287
MCDDEETTALVCDNG

ACTC1

1

P68032
MVICEEEGDDDVIAD

CIC

441

Q96RK0
TCESGAGSEVEVDMF

SPATA31A3

846

Q5VYP0
MGNDISAEDICAEDI

ZBTB11

456

O95625
GSRNSCEGEDEEEME

USP4

651

Q13107
MEICATDAVDDMEEG

TSR1

326

Q2NL82
CDIIDSSDEMDAQEE

TMEM183A

91

Q8IXX5
TCESGAGSEVEVDMF

SPATA31A1

846

Q5TZJ5
TCESGAGSEVEVDMF

SPATA31A5

846

Q5VU36
DDEDACRDTETTEAM

PPP1R2B

81

Q6NXS1
DVCADMVGTFTDTED

RBP4

86

P02753
MADEEAEQERLSCGE

ZNF292

1

O60281
GSATEDKDSMETDDC

NUP188

1256

Q5SRE5
TTQMSDEEEDDDGCD

WASHC2C

246

Q9Y4E1
DDDMEGDEAVVRCTL

SNRNP200

226

O75643
TTQMSDEEEDDDGCD

WASHC2A

246

Q641Q2
ASTDEQDAMDGELVC

XPO7

511

Q9UIA9
TEGGDICMEEEEEHS

ZNF236

1086

Q9UL36
EEGSDDCSEMCDGEE

SP140

386

Q13342
DCSEMCDGEERQEAS

SP140

391

Q13342
CEDTEAMDDVVEQDA

ZNF622

221

Q969S3
VAMEASSDGEEDAES

PPP6R3

771

Q5H9R7
ESSAELVAESMGEEC

GLDC

491

P23378
DMVCESSVTDEDSDF

KIAA1958

146

Q8N8K9
CTWGMGEDAVEDDAE

SLC4A1AP

336

Q9BWU0
SVDECDDSDGTEDMD

MYT1L

86

Q9UL68