Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessendocardial cell differentiation

NRG1 SMAD4

2.11e-056252GO:0060956
GeneOntologyBiologicalProcesscardiac endothelial cell differentiation

NRG1 SMAD4

3.93e-058252GO:0003348
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

ROBO1 NRG1 PRAG1 DENND3 SPRY4

4.34e-05333255GO:0051056
GeneOntologyBiologicalProcessendocardium development

NRG1 SMAD4

1.09e-0413252GO:0003157
GeneOntologyBiologicalProcesspositive regulation of small GTPase mediated signal transduction

ROBO1 NRG1 PRAG1

1.84e-0492253GO:0051057
DomainWD40_repeat_CS

GEMIN5 NEDD1 WDFY4 DENND3

5.31e-05164244IPR019775
DomainWD40

GEMIN5 NEDD1 WDFY4 DENND3

3.09e-04259244PF00400
DomainWD40

GEMIN5 NEDD1 WDFY4 DENND3

3.51e-04268244SM00320
DomainWD40_repeat

GEMIN5 NEDD1 WDFY4 DENND3

3.72e-04272244IPR001680
DomainWD_REPEATS_1

GEMIN5 NEDD1 WDFY4 DENND3

4.04e-04278244PS00678
DomainWD_REPEATS_2

GEMIN5 NEDD1 WDFY4 DENND3

4.09e-04279244PS50082
DomainWD_REPEATS_REGION

GEMIN5 NEDD1 WDFY4 DENND3

4.09e-04279244PS50294
DomainWD40_repeat_dom

GEMIN5 NEDD1 WDFY4 DENND3

5.18e-04297244IPR017986
Domain-

GEMIN5 NEDD1 WDFY4 DENND3

7.95e-043332442.130.10.10
DomainWD40/YVTN_repeat-like_dom

GEMIN5 NEDD1 WDFY4 DENND3

8.13e-04335244IPR015943
DomainIg_I-set

ROBO1 NRG1 SDK1

1.79e-03190243IPR013098
DomainI-set

ROBO1 NRG1 SDK1

1.79e-03190243PF07679
DomainIGc2

ROBO1 NRG1 SDK1

3.27e-03235243SM00408
DomainIg_sub2

ROBO1 NRG1 SDK1

3.27e-03235243IPR003598
DomainIG

ROBO1 NRG1 SDK1

1.62e-02421243SM00409
DomainIg_sub

ROBO1 NRG1 SDK1

1.62e-02421243IPR003599
Domainfn3

ROBO1 SDK1

1.82e-02162242PF00041
PathwayREACTOME_ROLE_OF_ABL_IN_ROBO_SLIT_SIGNALING

ROBO1 CAP2

4.80e-058192M27351
Pubmed

Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.

MUC16 SMAD4

5.37e-06526228287406
Pubmed

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

ZNF43 ZNF114

6.41e-05162628467795
Pubmed

Slit2 activity in the migration of guidepost neurons shapes thalamic projections during development and evolution.

ROBO1 NRG1

7.26e-051726221435555
Pubmed

Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction.

ROBO1 SMAD4

2.47e-043126222282597
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

MUC16 SDK1 TNRC6A

2.75e-0417026323314748
Pubmed

A human MAP kinase interactome.

ROBO1 KIAA1549L CAP2 TNRC6A

4.41e-0448626420936779
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DIP2C WDFY4 ATRNL1 DENND3

4.66e-0449326415368895
Pubmed

Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up.

ROBO1 NRG1

5.22e-044526221041608
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF43 ZNF826P

2.18e-03122262chr19p12
GeneFamilyWD repeat domain containing

GEMIN5 NEDD1 WDFY4 DENND3

1.12e-04262184362
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ROBO1 NRG1 SDK1

5.13e-04161183593
GeneFamilyFibronectin type III domain containing

ROBO1 SDK1

1.09e-02160182555
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DIP2C ROBO1 NRG1 ATRNL1

3.07e-06182254ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DIP2C NRG1 ATRNL1 MAMLD1

3.27e-06185254e58a009aaf342be019a909747b1895d5987d4daf
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ROBO1 NRG1 SDK1 SPRY4

3.49e-06188254997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ROBO1 PRAG1 SDK1 TNRC6A

3.79e-06192254916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ROBO1 PRAG1 SDK1 TNRC6A

3.87e-06193254e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ROBO1 SDK1 ATRNL1 MAMLD1

4.03e-061952543d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMD4A KIAA1549L ATRNL1 CAP2

4.11e-06196254676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMD4A KIAA1549L ATRNL1 CAP2

4.28e-06198254c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMD4A KIAA1549L ATRNL1 CAP2

4.28e-061982546d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMD4A KIAA1549L ATRNL1 CAP2

4.28e-061982548ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMD4A KIAA1549L ATRNL1 CAP2

4.28e-061982540ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMD4A KIAA1549L ATRNL1 CAP2

4.28e-061982544ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

FRMD4A KIAA1549L ATRNL1 CAP2

4.46e-0620025448d801219bc771d6c7e151dc88ca4c179988de85
ToppCellPBMC-Control-cDC_2|Control / Compartment, Disease Groups and Clusters

MUC16 SDK1 MAMLD1

8.39e-051532534ee37266b0054f276c7a73ab9220f681b9d74c71
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRMD4A ATRNL1 SPRY4

9.06e-05157253bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PRAG1 WDFY4 CHRNA2

9.41e-051592532881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC16 ROBO1 FRMD4A

1.09e-041672538b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 SDK1 ATRNL1

1.11e-04168253a086c306be430adf0632ba53e98cd8014d2de330
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 DENND3 CAP2

1.15e-0417025399dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 DENND3 CAP2

1.15e-041702533a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 FRMD4A MAMLD1

1.15e-04170253876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 FRMD4A MAMLD1

1.15e-041702531f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 DENND3 CAP2

1.15e-04170253cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIP2C GEMIN5 DENND3

1.17e-04171253d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRG1 PRAG1 SDK1

1.19e-041722530c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

FRMD4A SDK1 ATRNL1

1.19e-0417225336a96714a0eb6ac438648135336c9791881ddadb
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRG1 PRAG1 SDK1

1.19e-04172253eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.23e-04174253fdadac1eaab2c4a67e4832f0901df22e893add6a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.23e-041742538d8cf8ad17dcc364f867e36b10834a21c0e36ad2
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.29e-0417725384116796ca4c7007508c0f1a68a1135c7b922278
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.31e-041782533c973aac16988e88f5677d3d695dd772ccfd6570
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 SDK1 ATRNL1

1.31e-04178253544379f5a6145429762258d426b876bb36c112f5
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMD4A PRAG1 GBGT1

1.31e-04178253de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.34e-0417925397ba67a856680f24846244c0b92c886cc0e79537
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRG1 SDK1 SPRY4

1.34e-04179253a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRMD4A DENND3 SPRY4

1.36e-04180253efc4c5a4dea456527526bbfd88cf70d803893671
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-4|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

ROBO1 FRMD4A SMAD4

1.36e-04180253886ebaf9cf8992e8dd13fca799a1d1a2a9ce73d8
ToppCellcritical-Lymphoid-NK|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

KIAA1549L ATRNL1 SPRY4

1.36e-041802535abf778395392244daaec876f306ed7e4f388686
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.38e-04181253062f00736eed96e4f4327615d093558dd7d82b20
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.38e-041812537846c7b33d1b89364c5a704edaa86520db731c89
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.40e-04182253d3a037268f026eb2f84428b1821022503cef7756
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.40e-04182253420a8fd30543e37a66ba0786215d056d308660d0
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRMD4A ATRNL1 SPRY4

1.43e-041832538a799807fbf24456a9811e0c64068187940a2f71
ToppCell3'_v3-Lung-Myeloid_Dendritic-DC1|Lung / Manually curated celltypes from each tissue

ROBO1 WDFY4 SDK1

1.43e-04183253e4cbd39575b5a4612d9934532e3bad63286f8aa5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.45e-0418425332473dbdb2de66391157c5814ef34e790806e4f2
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRMD4A ATRNL1 SPRY4

1.45e-04184253102b6f621a5b551e622f97b12d787c080b052a72
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRMD4A ATRNL1 SPRY4

1.45e-04184253689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellControl-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ROBO1 WDFY4 SDK1

1.45e-04184253c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

KIAA1549L SDK1 ATRNL1

1.45e-04184253ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell3'_v3-GI_small-bowel-Myeloid_Dendritic-DC1|GI_small-bowel / Manually curated celltypes from each tissue

ROBO1 WDFY4 SDK1

1.45e-041842538e393eea7240584a3cef718bee094e2705ec1891
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.47e-041852530b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCellCOPD-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

DIP2C MUC16 ATRNL1

1.47e-0418525323579988036fc1925992c31919750f9b3fe9f790
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.47e-04185253bdfa8c284bbc5e85c806327fbb7778cf16242a38
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRMD4A SDK1 CAP2

1.50e-041862534780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell10x5'-Liver-Myeloid_Dendritic-DC1|Liver / Manually curated celltypes from each tissue

ROBO1 WDFY4 SDK1

1.50e-04186253e823529ffd06352c6bdec102f221fdf27f7c7369
ToppCellControl-Myeloid-cDC1|Control / Disease state, Lineage and Cell class

ROBO1 WDFY4 SDK1

1.50e-04186253b05c394aa3573ba855abc3066739ca193883b0c3
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.52e-04187253ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SDK1 ATRNL1 MAMLD1

1.52e-0418725376bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.54e-041882536ee3f8f94ea7bdf652c9575fc65bff08070093a4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 ATRNL1 MAMLD1

1.57e-0418925371397e993a77d70b2eeede240bdfc7660b558987
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 ATRNL1 MAMLD1

1.57e-041892534eea4759520c312bd17a681034d8074e47093d2b
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

DIP2C NRG1 DENND3

1.57e-041892535a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ROBO1 PRAG1 ATRNL1

1.59e-04190253d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 ATRNL1 MAMLD1

1.59e-041902531121eb607a984c59fbffe7220837fc178745aa55
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRG1 KIAA1549L ATRNL1

1.59e-04190253d594da827e3c16644952b9589cc12b947ce36279
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 ATRNL1 MAMLD1

1.59e-04190253048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROBO1 FRMD4A SDK1

1.59e-0419025345df8fee00f8949937863159d7aa042e72748d9b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 ATRNL1 MAMLD1

1.62e-04191253a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRMD4A SDK1 MAMLD1

1.62e-0419125308720998aa55131d7377c4c67c4c935865bd7d79
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 ATRNL1 MAMLD1

1.62e-041912538f6d592edc32fdb901af30501d4360512334e8c2
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.64e-041922536a252e298f8a454623fa9c1c893a7a45a886d694
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.64e-041922533abee376c37c3646da33ac381aa63d50a01607a6
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.64e-0419225367d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ROBO1 PRAG1 ATRNL1

1.64e-0419225372881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROBO1 FRMD4A SDK1

1.64e-04192253df1545670370fb1010c567cd059c2783eab315f7
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

DIP2C SDK1 TNRC6A

1.64e-04192253e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

ROBO1 SDK1 TNRC6A

1.67e-04193253503a979328c68b096680b71359a26f02fafdff35
ToppCellLA|World / Chamber and Cluster_Paper

ROBO1 FRMD4A SDK1

1.67e-04193253d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ROBO1 PRAG1 ATRNL1

1.67e-041932532f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ROBO1 SDK1 MAMLD1

1.67e-0419325399525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 ATRNL1 MAMLD1

1.69e-04194253ba7f971fb9a19423602da60770f23d9fead4a451
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 ATRNL1 MAMLD1

1.69e-04194253cf0244a29934e515446ac917d3c30672b460fb04
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRG1 KIAA1549L CAP2

1.72e-041952532e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ROBO1 FRMD4A PRAG1

1.72e-041952530e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 SDK1 CHRNA2

1.74e-041962537af6c5147ac859353504d19727dbe24f63a29dd4
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

PRAG1 ATRNL1 SPRY4

1.74e-04196253e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 SDK1 CAP2

1.74e-04196253b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 SDK1 CAP2

1.74e-04196253c366f980cc04abfe1c0c14746c11810c812a42c0
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

DIP2C ROBO1 SDK1

1.77e-04197253f1c8936986123a3151140c374fcd62d6705c530b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 ATRNL1 MAMLD1

1.77e-041972539b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

DIP2C ROBO1 SDK1

1.77e-04197253fb847f2277609c31fffcdf49517243ce0684facf
ToppCellEpithelial_cells-AT1-AT2_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

NRG1 PRAG1 DENND3

1.80e-04198253fbc46b20bcd44f2083170aacbc6f5dd00fba685c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 ATRNL1 MAMLD1

1.80e-04198253a860246bcea847249a78fd2e86ed8e04371060db
ToppCellhuman_hepatoblastoma-Tumor_cells-T9|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NRG1 PRAG1 CAP2

1.82e-04199253e9c83555d2197b740797a9f33b64f8f7a7ba1ee2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATRNL1 SPRY4 MAMLD1

1.82e-04199253333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATRNL1 SPRY4 MAMLD1

1.82e-04199253e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-ADAMTSL1|Neuronal / cells hierarchy compared to all cells using T-Statistic

ROBO1 SDK1 CHRNA2

1.85e-04200253e1fca7ee2dc18c7fded53c3561f519c1fcd9767a
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CBLN1-L2-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

ROBO1 SDK1 CHRNA2

1.85e-042002532086024ce808b8796ed508a229b098eb02f8828a
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial|GW10 / Sample Type, Dataset, Time_group, and Cell type.

KIAA1549L NEDD1 SPRY4

1.85e-04200253ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

ROBO1 FRMD4A PRAG1

1.85e-04200253332905a686356cd1e024d40679be98e9d8b1b5e8
DrugVanadates

DIP2C FLG FRMD4A NRG1 PRAG1 ZNF43 GBGT1 ZNF114 MAMLD1

5.64e-061302259ctd:D014638
Diseasea disintegrin and metalloproteinase with thrombospondin motifs 13 measurement

NRG1 GBGT1

1.01e-0417262EFO_0008011
Diseaseresponse to vaccine, cytokine measurement

DIP2C SMAD4 MAMLD1

2.06e-04131263EFO_0004645, EFO_0004873
Diseaseinternet addiction disorder

NRG1 NEDD1

3.88e-0433262EFO_0803368
Diseaseasthma

MUC16 FLG PRAG1 SPRY4 SMAD4

4.45e-04751265MONDO_0004979
DiseaseAlzheimer disease

FRMD4A SDK1 DENND3 TNRC6A

8.09e-04485264MONDO_0004975
DiseaseHepatic fibrosis

KIAA1549L SDK1

8.56e-0449262HP_0001395
Diseasehair morphology measurement

FRMD4A PRAG1

1.04e-0354262EFO_0007821
Diseaseovarian cancer (is_implicated_in)

MUC16 SMAD4

1.12e-0356262DOID:2394 (is_implicated_in)
Diseaseage at initiation of smoking

SDK1 CHRNA2

1.55e-0366262EFO_0021784
DiseaseLung Neoplasms

ROBO1 NRG1 CHRNA2

1.60e-03265263C0024121
DiseaseMalignant neoplasm of lung

ROBO1 NRG1 CHRNA2

1.62e-03266263C0242379
Diseaseovarian cancer (is_marker_for)

NRG1 SMAD4

1.64e-0368262DOID:2394 (is_marker_for)
DiseaseContact hypersensitivity

FLG NRG1

1.79e-0371262C0162351
DiseaseContact Dermatitis

FLG NRG1

1.79e-0371262C0011616
Diseasepsychotic symptoms

DIP2C WDFY4

1.94e-0374262EFO_0005940
Diseasewhite matter hyperintensity measurement

FRMD4A PRAG1 DENND3

2.32e-03302263EFO_0005665
Diseaseresponse to selective serotonin reuptake inhibitor

NRG1 CAP2

2.37e-0382262EFO_0005658
Diseasecarotid plaque build

ROBO1 ATRNL1

2.49e-0384262EFO_0006501
DiseaseEczema

FLG SPRY4 SMAD4

2.50e-03310263HP_0000964

Protein segments in the cluster

PeptideGeneStartEntry
TKAHLFSTGTVHWVP

CHRNA2

161

Q15822
QVSTHKQSESSHGWT

FLG

796

P20930
ASSWTIHQHSFKVGT

DENND3

931

A2RUS2
AHHSTTVTQTPSHSW

NRG1

341

Q02297
TVTQTPSHSWSNGHT

NRG1

346

Q02297
PSHSWSNGHTESILS

NRG1

351

Q02297
WVTSSEHASHSTIPA

MUC16

3956

Q8WXI7
HTSPHGISSICWSSN

NEDD1

31

Q8NHV4
EHHTTGLTWSKTGPV

CAP2

201

P40123
KHQNTPSIGLHWRSS

CSNKA2IP

96

A0A1B0GTH6
PHLGVSGSSTKWHSE

KIAA1549L

16

Q6ZVL6
SSPHHILTWQTGEAT

FRMD4A

1006

Q9P2Q2
KTSVPHHVVWSLFNT

nan

51

C9JQL5
SSIPIQGHSHWEETS

GBGT1

166

Q8N5D6
EHWISQAIHGSTTST

DIP2C

161

Q9Y2E4
HSQSWSTKTPTVLGH

ATRNL1

391

Q5VV63
AWTSAASSVKPQHQH

MAMLD1

646

Q13495
HGIGTASWNHSTTVP

HOMEZ

241

Q8IX15
VSPNSSHSHAVVLSW

SDK1

676

Q7Z5N4
THHWISFSGRPSSVS

SPRY4

86

Q9C004
HHNSTTTWTGSRTAP

SMAD4

261

Q13485
NGIKTFTWSSSPHKH

ZNF826P

96

Q6ZT77
SWTHSKARTPEGTHS

SPEM3

241

A0A1B0GUW6
SGHTAKITSVAWSPH

GEMIN5

636

Q8TEQ6
SNVAHHSKVTLWSGS

WDFY4

2186

Q6ZS81
HNPTVLSSSSIEVHW

ROBO1

681

Q9Y6N7
SNSTTWHRLHPTDGS

PRAG1

666

Q86YV5
NWPSTLTKHNRIHTG

ZNF43

436

P17038
LTWSPGSVTNTSLAH

TNRC6A

1701

Q8NDV7
KSSTWTGSQNTVHHI

ZNF114

196

Q8NC26