Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainAT_hook

BOD1L1 ZNF653

7.43e-0427282SM00384
DomainAT_hook_DNA-bd_motif

BOD1L1 ZNF653

7.43e-0427282IPR017956
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PTPN3 BOD1L1 CLASP2 IRS2 CDC25B ABTB2

5.35e-0586128636931259
Pubmed

Genome-wide association study for serum complement C3 and C4 levels in healthy Chinese subjects.

C3 BTNL2

8.44e-051728223028341
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

BLM C3 CLASP2 HAUS4 TBKBP1 CDC25B

5.45e-04132128627173435
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

BLM USP36 C3 STAU1

5.77e-0448328436912080
Pubmed

Congenital Diaphragmatic Hernia Overview

RIPPLY2 HDAC8

6.33e-044628220301533
Pubmed

Substrate-trapping techniques in the identification of cellular PTP targets.

PTPN3 IRS2

7.18e-044928215588985
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BLM FOXS1 COL16A1 HECW1 ADAM23

4.76e-081592857ed659163f45e0c4df4782997c0786900c8186c8
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BLM KLHDC1 CDC25B

1.21e-04154283ec920cae12ea1d14b6c973f6e903f895f80e3c50
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRME1 GSPT2 CDC25B

1.35e-041602839f24ee4fe1ba4590dce5dd4d43707fb007dca82f
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRME1 GSPT2 CDC25B

1.35e-041602833b3b99305558f5b49d050fb9b249007630ea9085
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BLM FOXS1 COL16A1

1.59e-04169283335619507857383c3b0b507cdf05d786ed59e585
ToppCellCV-Mild-7|CV / Virus stimulation, Condition and Cluster

KLHDC1 ABTB2 ALPK2

1.62e-0417028325ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCellCV-Mild-7|Mild / Virus stimulation, Condition and Cluster

KLHDC1 ABTB2 ALPK2

1.71e-04173283c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXS1 GSPT2 ABTB2

1.71e-04173283a37f38478473290fe35aea8684befc3bf95b161f
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDC42BPG ADAM23 ZNF653

1.79e-0417628324b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDC42BPG ADAM23 ZNF653

1.82e-04177283f360f7099570d248531897b96e0de282e58f59e9
ToppCellfacs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLM BRME1 HECW1

1.89e-04179283d76a05f1fee7f2f7b7b7994d3622e96f02b49432
ToppCellfacs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLM BRME1 HECW1

1.89e-041792836be47c877250968a916c711ba0787eb7b4c5443d
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL16A1 ADAM23 ITPK1

1.92e-041802831e819c5c87704ec6535dfeaae56561895e239d07
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXS1 C3 ALPK2

1.92e-04180283f103e161e966c257eac97e1b30a461c4ed9cafc2
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXS1 COL16A1 GSPT2

1.98e-04182283be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXS1 COL16A1 GSPT2

1.98e-0418228374dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLM HAUS4 CDC25B

2.01e-04183283769a022fe8568ec49e66f792cc5777e713a7571c
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLM HAUS4 CDC25B

2.01e-04183283aac0695fafa59cabd920ee18b1139d3e00d898e8
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXS1 COL16A1 GSPT2

2.08e-04185283a6cd90f8f30c7bdf66958cf403e73c193aa32f5e
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXS1 COL16A1 GSPT2

2.08e-041852835053f932e2adfcf4d6faaecff2999ac53d8d7aa5
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BLM COL16A1 GSPT2

2.14e-041872838e8b147258982b359447add5027318f5b6d51963
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs|metastatic_Lymph_Node / Location, Cell class and cell subclass

C3 COL16A1 ALPK2

2.14e-04187283e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

C3 PTPN3 IRS2

2.18e-041882834bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

C3 COL16A1 ABTB2

2.18e-04188283706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

USP36 IRS2 ADAM23

2.21e-04189283284f39dfacec76004daae9dd5317fb7b1f04fa99
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3 IRS2 ALPK2

2.32e-041922830dc1f46e40346ed0b286e53b106a812441575100
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXS1 C3 ALPK2

2.35e-04193283c5bd0ed6f57459e54d2463318e8d9b1879718e63
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

C3 IRS2 ABTB2

2.39e-04194283014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXS1 C3 ALPK2

2.39e-04194283c45e9d09b5cd6973de6c3f1713b3bf36fa4bfe57
ToppCellfacs-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLASP2 IRS2 COL16A1

2.42e-04195283c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3 IRS2 COL16A1

2.46e-04196283b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3 IRS2 COL16A1

2.46e-04196283787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXS1 C3 ALPK2

2.50e-041972835fbbc570a4e77c703f569a4f85ce2d8af67d6297
ToppCellSigmoid-(1)_T_cell-(16)_Tfh|Sigmoid / shred on region, Cell_type, and subtype

CDC42BPG ADAM23 ZNF653

2.57e-04199283a61bf52d2d359746433623ee00337124f1f84f61
ToppCellSigmoid-T_cell-Tfh|Sigmoid / Region, Cell class and subclass

CDC42BPG ADAM23 ZNF653

2.57e-04199283fa9404a021a015d1d571c324780b6eef2da47c4c
ToppCellSigmoid-T_cell-Tfh|T_cell / Region, Cell class and subclass

CDC42BPG ADAM23 ZNF653

2.61e-04200283dd7dcf25520f065bf0d33d589f3c176f63875dc9
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FOXS1 C3 COL16A1

2.61e-042002834c3c11dd5e71ebc3d62264eeaeb71a850b149779
Diseaseasthma, body mass index

USP36 COL16A1

7.85e-0514282EFO_0004340, MONDO_0004979
DiseaseImmunologic Deficiency Syndromes

BLM C3

2.17e-0423282C0021051
Diseasethoracic aortic aneurysm

PTPN3 COL16A1

3.72e-0430282EFO_0004282
DiseaseHeart Failure, Diastolic

PTPN3 CDC25B

4.50e-0433282C1135196
DiseaseInsulin Sensitivity

C3 IRS2

1.49e-0360282C0920563
DiseaseInsulin Resistance

C3 IRS2

1.49e-0360282C0021655
Diseaseintellectual disability (implicated_via_orthology)

BOD1L1 IRS2

2.31e-0375282DOID:1059 (implicated_via_orthology)
Diseasechronic obstructive pulmonary disease (is_marker_for)

C3 HDAC8

3.82e-0397282DOID:3083 (is_marker_for)
Diseaseloneliness measurement

BTNL2 STAU1

6.17e-03124282EFO_0007865
DiseaseRS-warfarin measurement

PTPN3 CDC25B

6.56e-03128282EFO_0803325

Protein segments in the cluster

PeptideGeneStartEntry
GYVEDGTPCGPSMMC

ADAM23

706

O75077
GQEDGEMQPMCSSDG

BTNL2

371

Q9UIR0
MGCGSRVSGDAGPMV

ALPK2

381

Q86TB3
GHCNPSDCFGAMPME

COL16A1

1576

Q07092
TPSGCGEQNMIGMTP

C3

1006

P01024
PMCPEGGDTLEGSMA

PTPN3

621

P26045
ASMGSEGLGGDADPM

CDC42BPG

1491

Q6DT37
SASPGCCGSMMGQDA

ITPK1

356

Q13572
DSPMNNLMESGSGEP

HECW1

366

Q76N89
SGDSGPPEESGQEMM

GSPT2

166

Q8IYD1
SSDAGLCMDSPSPMD

CDC25B

106

P30305
MASDGASALPGPDMS

NUTM1

1

Q86Y26
GSGSCRSDDYMPMSP

IRS2

666

Q9Y4H2
VPGGCEGPMTSAASD

BOD1L1

1971

Q8NFC6
LAPGSGESMMGAGDS

BRME1

421

Q0VDD7
DGPMEGDSCPTGNSM

BLM

436

P54132
GAMPASMCPATTDGR

FOXS1

171

O43638
MEGELPASMSGSCGA

KLHDC1

61

Q8N7A1
GDPMCSFNMTPVGIG

HDAC8

271

Q9BY41
MASGDFCSPGEGMEI

HAUS4

1

Q9H6D7
GQGPMCESNSTMPGP

NIT1

171

Q86X76
GPDGVNTMDDQGMTP

ABTB2

511

Q8N961
DGDSMCGGPGMSDPR

CLASP2

971

O75122
PGSGLGEEVPCAMME

ZNF653

346

Q96CK0
TEMPRTGNGPMSVCG

STAU1

561

O95793
AEAMPDGPGMTAASG

RIPPLY2

56

Q5TAB7
SPGDPSLGGDMCSAS

TBKBP1

26

A7MCY6
HSCSPMGDGDPEAME

USP36

936

Q9P275