Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B RGS16 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.69e-06	279	160	12	GO:0005096
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E RALGDS TBC1D3 TBC1D3H TBC1D3L TBC1D3D ARHGEF17 TBC1D3C TBC1D3B RGS16 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	6.03e-05	507	160	14	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E RALGDS TBC1D3 TBC1D3H TBC1D3L TBC1D3D ARHGEF17 TBC1D3C TBC1D3B RGS16 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	6.03e-05	507	160	14	GO:0030695
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	8.08e-10	109	159	11	GO:0090630
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B RGS16 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	4.40e-07	244	159	12	GO:0043547
GeneOntologyBiologicalProcess	positive regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H PRELID1 TBC1D3L TBC1D3D PIDD1 NLRP1 TBC1D3C TBC1D3B RGS16 MAP3K5 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.65e-06	499	159	16	GO:0051345
GeneOntologyBiologicalProcess	regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B RGS16 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.17e-05	335	159	12	GO:0043087
GeneOntologyBiologicalProcess	Rab protein signal transduction	RAB4B RAB30 RAB39B RAB4A	1.84e-05	21	159	4	GO:0032482
GeneOntologyBiologicalProcess	regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H PRELID1 TBC1D3L TBC1D3D PIDD1 NLRP1 TBC1D3C TBC1D3B ITIH1 RGS16 MAP3K5 VCAN TBC1D3I PPP6R2 TBC1D3G TBC1D3K TBC1D3F	4.82e-05	878	159	19	GO:0051336
Domain	TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	8.72e-12	49	158	10	SM00164
Domain	RabGAP-TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.01e-11	53	158	10	PF00566
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.97e-11	55	158	10	IPR000195
Domain	TBC_RABGAP	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.97e-11	55	158	10	PS50086
Domain	WD40_repeat_dom	SEH1L DCAF6 RBBP5 ARHGEF17 ZNF106 NWD2 NBEAL2 ATG16L2 WDR44 TBL1X	2.24e-04	297	158	10	IPR017986
Domain	RAB	RAB4B RAB30 RAB39B RAB37 RAB4A	3.84e-04	73	158	5	PS51419
Domain	Lys_sp_deMease-like_dom	KDM5C KDM5D	4.22e-04	4	158	2	IPR013637
Domain	PLU-1	KDM5C KDM5D	4.22e-04	4	158	2	PF08429
Domain	WD40	SEH1L DCAF6 RBBP5 ZNF106 NWD2 NBEAL2 ATG16L2 WDR44 TBL1X	4.71e-04	268	158	9	SM00320
Domain	Fibrinogen_CS	ANGPT2 FCN2 FIBCD1	5.21e-04	19	158	3	IPR020837
Domain	WD40_repeat	SEH1L DCAF6 RBBP5 ZNF106 NWD2 NBEAL2 ATG16L2 WDR44 TBL1X	5.24e-04	272	158	9	IPR001680
Domain	-	SEH1L DCAF6 RBBP5 ARHGEF17 ZNF106 NWD2 NBEAL2 ATG16L2 WDR44 TBL1X	5.52e-04	333	158	10	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	SEH1L DCAF6 RBBP5 ARHGEF17 ZNF106 NWD2 NBEAL2 ATG16L2 WDR44 TBL1X	5.79e-04	335	158	10	IPR015943
Domain	WD_REPEATS_1	SEH1L DCAF6 RBBP5 ZNF106 NWD2 NBEAL2 ATG16L2 WDR44 TBL1X	6.13e-04	278	158	9	PS00678
Domain	WD_REPEATS_2	SEH1L DCAF6 RBBP5 ZNF106 NWD2 NBEAL2 ATG16L2 WDR44 TBL1X	6.29e-04	279	158	9	PS50082
Domain	WD_REPEATS_REGION	SEH1L DCAF6 RBBP5 ZNF106 NWD2 NBEAL2 ATG16L2 WDR44 TBL1X	6.29e-04	279	158	9	PS50294
Domain	VWFA	COL6A1 CPNE9 MATN4 ITIH1 HMCN2	6.57e-04	82	158	5	PS50234
Domain	zf-C5HC2	KDM5C KDM5D	6.99e-04	5	158	2	PF02928
Domain	Znf_C5HC2	KDM5C KDM5D	6.99e-04	5	158	2	IPR004198
Domain	VWA	COL6A1 CPNE9 MATN4 ITIH1 HMCN2	7.33e-04	84	158	5	SM00327
Domain	Fibrinogen_a/b/g_C_2	ANGPT2 FCN2 FIBCD1	1.06e-03	24	158	3	IPR014715
Domain	JmjC	KDM5C KDM5D JMJD1C	1.06e-03	24	158	3	PF02373
Domain	-	ANGPT2 FCN2 FIBCD1	1.06e-03	24	158	3	4.10.530.10
Pathway	WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K	1.27e-07	99	117	9	M46448
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.24e-26	11	167	11	16863688
Pubmed	DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.	TBC1D3E SDK2 TBC1D3 TBC1D3H TBC1D3D TBC1D3B TBC1D3G TBC1D3F	2.75e-09	74	167	8	16625196
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3D TBC1D3F	4.33e-07	4	167	3	12359748
Pubmed	Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.	TBC1D3 TBC1D3D TBC1D3F	4.33e-07	4	167	3	8406013
Pubmed	The Tre2 (USP6) oncogene is a hominoid-specific gene.	TBC1D3 TBC1D3D TBC1D3C	1.08e-06	5	167	3	12604796
Pubmed	Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.	TBC1D3 TBC1D3D TBC1D3F	1.08e-06	5	167	3	8471161
Pubmed	Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.	KDM5C KDM5D	2.29e-05	2	167	2	10441747
Pubmed	Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.	KDM5C KDM5D	2.29e-05	2	167	2	16416087
Pubmed	Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.	KDM5C KDM5D	2.29e-05	2	167	2	32081420
Pubmed	Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium.	DUOX2 NOX1	2.29e-05	2	167	2	27930931
Pubmed	A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.	KDM5C KDM5D	2.29e-05	2	167	2	7524912
Pubmed	Lysine demethylase 5C epigenetically reduces transcription of ITIH1 that results in augmented progression of liver hepatocellular carcinoma.	KDM5C ITIH1	2.29e-05	2	167	2	35080113
Pubmed	Cisplatin-induced ototoxicity in pediatric solid tumors: the role of glutathione S-transferases and megalin genetic polymorphisms.	GSTT1 LRP2	2.29e-05	2	167	2	23274376
Pubmed	Increased NOX1 and DUOX2 expression in the colonic mucosa of patients with chronic functional constipation.	DUOX2 NOX1	2.29e-05	2	167	2	35960091
Pubmed	Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.	KDM5C KDM5D	2.29e-05	2	167	2	9060413
Pubmed	Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity.	RAB4B RAB30 RAB39B RAB37 RAB4A	2.59e-05	72	167	5	16923123
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	STBD1 SYNM GIGYF1 UNC45A JMJD1C AXIN1 PLSCR3 LZTS2	4.32e-05	263	167	8	34702444
Pubmed	Galectin-8 Favors the Presentation of Surface-Tethered Antigens by Stabilizing the B Cell Immune Synapse.	HLA-DQB2 LGALS8	6.85e-05	3	167	2	30540943
Pubmed	Diversity of human copy number variation and multicopy genes.	TBC1D3E TBC1D3G	6.85e-05	3	167	2	21030649
Pubmed	Rab4b is a small GTPase involved in the control of the glucose transporter GLUT4 localization in adipocyte.	RAB4B RAB4A	6.85e-05	3	167	2	19590752
Pubmed	Identification of a mouse male-specific transplantation antigen, H-Y.	KDM5C KDM5D	6.85e-05	3	167	2	7544442
Pubmed	Congenital Muscular Dystrophy Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	POMT2 COL6A1 FKRP	7.04e-05	17	167	3	20301468
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SPHK2 B4GALNT4 RNPEPL1 MYOM3 ZDHHC7 RELB MIB2 TTYH3 FBXO46 RGS16 MAP3K5 NBEAL2 KANK3 PKD1 DOT1L SNAPC4	9.11e-05	1105	167	16	35748872
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KDM5C KDM5D JMJD1C DOT1L	9.18e-05	49	167	4	34368113
Pubmed	Identification and characterization of the potential promoter regions of 1031 kinds of human genes.	COL6A1 RBBP5 TOR1A SLC35B1	1.16e-04	52	167	4	11337467
Pubmed	Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.	KDM5C KDM5D	1.37e-04	4	167	2	16541399
Pubmed	The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.	KDM5C KDM5D	1.37e-04	4	167	2	17320160
Pubmed	A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.	KDM5C KDM5D	1.37e-04	4	167	2	7951230
Pubmed	Plasmacytoid dendritic cells prime alloreactive T cells to mediate graft-versus-host disease as antigen-presenting cells.	HLA-DQB2 TICAM1	1.37e-04	4	167	2	19144988
Pubmed	GST M1/T1 and MTHFR polymorphisms as risk factors for hypertension.	GSTT1 NOX1	1.37e-04	4	167	2	17182005
Pubmed	Functional cross-talk between Rab14 and Rab4 through a dual effector, RUFY1/Rabip4.	RAB4B RAB4A	1.37e-04	4	167	2	20534812
Pubmed	Fragile TIM-4-expressing tissue resident macrophages are migratory and immunoregulatory.	HLA-DQB2 SIGLEC1	1.37e-04	4	167	2	24983317
Pubmed	Double-stranded RNA induces shedding of the 34-kDa soluble TNFR1 from human airway epithelial cells via TLR3-TRIF-RIP1-dependent signaling: roles for dual oxidase 2- and caspase-dependent pathways.	TICAM1 DUOX2	1.37e-04	4	167	2	21148036
Pubmed	TLR3 ligand stimulates fully functional memory CD8+ T cells in the absence of CD4+ T-cell help.	HLA-DQB2 TICAM1	1.37e-04	4	167	2	17339421
Pubmed	X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.	KDM5C KDM5D	1.37e-04	4	167	2	32732223
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL6A1 LAMA3 MATN4 ITIH1 HMCN2 VCAN	1.63e-04	167	167	6	22159717
Pubmed	Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport.	RAB4B RAB30 RAB37 RAB4A	1.78e-04	58	167	4	11856727
Pubmed	Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.	RAB4B RAB30 RAB39B RAB37	2.16e-04	61	167	4	12578829
Pubmed	Epithelial TLR4 Signaling Activates DUOX2 to Induce Microbiota-Driven Tumorigenesis.	DUOX2 NOX1	2.27e-04	5	167	2	33127391
Pubmed	c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease.	MAP3K5 PKD1	2.27e-04	5	167	2	34962918
Pubmed	Mechanoprotection by polycystins against apoptosis is mediated through the opening of stretch-activated K(2P) channels.	PKD1 KCNK10	2.27e-04	5	167	2	22832196
Pubmed	Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation.	DUOX2 NOX1	2.27e-04	5	167	2	34784249
Pubmed	The Gastric Mucosa from Patients Infected with CagA+ or VacA+ Helicobacter pylori Has a Lower Level of Dual Oxidase-2 Expression than Uninfected or Infected with CagA-/VacA- H. pylori.	DUOX2 NOX1	2.27e-04	5	167	2	27048452
Pubmed	The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.	RAB4B RAB30 RAB37 RAB4A	2.30e-04	62	167	4	11773082
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGDS SDK2 PACSIN1 KDM5C ADGRV1 TUBGCP6 NBEAL2 LZTS2 EDEM1 NIN	2.56e-04	529	167	10	14621295
Pubmed	Genetic link between renal birth defects and congenital heart disease.	BMP10 PKD1 LRP2	3.26e-04	28	167	3	27002738
Pubmed	The Rab protein family: genetic mapping of six Rab genes in the mouse.	RAB4B RAB4A	3.39e-04	6	167	2	8825628
Pubmed	APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury.	DUOX2 NOX1	3.39e-04	6	167	2	28165467
Pubmed	Versican is produced by Trif- and type I interferon-dependent signaling in macrophages and contributes to fine control of innate immunity in lungs.	TICAM1 VCAN	3.39e-04	6	167	2	28912382
Pubmed	Congenital muscular dystrophies with defective glycosylation of dystroglycan: a population study.	POMT2 FKRP	3.39e-04	6	167	2	19299310
Pubmed	Mouse models of human ocular disease for translational research.	RPGRIP1 FKRP	3.39e-04	6	167	2	28859131
Pubmed	TLR and B cell receptor signals to B cells differentially program primary and memory Th1 responses to Salmonella enterica.	HLA-DQB2 TICAM1	3.39e-04	6	167	2	20675594
Pubmed	Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells.	HLA-DQB2 TICAM1	3.39e-04	6	167	2	21098219
Pubmed	Syndapin I and endophilin I bind overlapping proline-rich regions of dynamin I: role in synaptic vesicle endocytosis.	SYNM PACSIN1	3.39e-04	6	167	2	17437541
Pubmed	Three novel collagen VI chains with high homology to the alpha3 chain.	COL6A1 LAMA3	4.74e-04	7	167	2	18276594
Pubmed	Resident cardiac macrophages mediate adaptive myocardial remodeling.	TICAM1 SIGLEC1	4.74e-04	7	167	2	34320366
Pubmed	Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase.	DUOX2 NOX1	4.74e-04	7	167	2	19005069
Pubmed	A human MAP kinase interactome.	RALGDS PACSIN1 LAMA3 MUC12 MAP3K5 ZNF106 MAP3K21 WDR44 TBC1D3F	6.03e-04	486	167	9	20936779
Pubmed	Reduced polyalanine-expanded Arx mutant protein in developing mouse subpallium alters Lmo1 transcriptional regulation.	KDM5C RAB39B	6.30e-04	8	167	2	24122442
Pubmed	Regulation of TRIF-mediated innate immune response by K27-linked polyubiquitination and deubiquitination.	TICAM1 USP19	6.30e-04	8	167	2	31511519
Pubmed	Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).	HLA-DQB2 RELB	6.30e-04	8	167	2	10925280
Pubmed	The microbiota regulates hematopoietic stem cell fate decisions by controlling iron availability in bone marrow.	TICAM1 SIGLEC1	6.30e-04	8	167	2	35065706
Pubmed	Essential role of Hand2 in interventricular septum formation and trabeculation during cardiac development.	BMP10 VCAN	6.30e-04	8	167	2	16530167
Pubmed	Host response. Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection.	TICAM1 SIGLEC1	6.30e-04	8	167	2	25657250
Pubmed	Sexually dimorphic gene expression in the developing mouse gonad.	AARD KDM5D DHH	6.36e-04	35	167	3	12617826
Pubmed	Donor colonic CD103+ dendritic cells determine the severity of acute graft-versus-host disease.	HLA-DQB2 TICAM1	8.07e-04	9	167	2	26169940
Pubmed	Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node.	SPHK2 SIGLEC1	8.07e-04	9	167	2	27487469
Pubmed	Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF.	TICAM1 RELB	8.07e-04	9	167	2	34529751
Pubmed	MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota.	HLA-DQB2 TICAM1	8.07e-04	9	167	2	31542340
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	NLRP1 IQCN LGALS8 GALNT8 LRP2 SIGLEC1 SLC35B1	8.30e-04	313	167	7	20800603
Pubmed	WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.	SEH1L ZNF106 ATG16L2	9.43e-04	40	167	3	29078390
Pubmed	Interaction cloning and characterization of the cDNA encoding the human prenylated rab acceptor (PRA1).	RAB4B RAB4A	1.01e-03	10	167	2	10329441
Pubmed	Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development.	SPHK2 NBEAL2	1.01e-03	10	167	2	25908104
Pubmed	Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis.	AXIN1 DHH	1.01e-03	10	167	2	21652647
Pubmed	Memory CD4+ T cells induce innate responses independently of pathogen.	HLA-DQB2 TICAM1	1.01e-03	10	167	2	20436484
Pubmed	Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis.	KDM5D TAF6L	1.01e-03	10	167	2	36646704
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DCAF6 KDM5C MMP21 GIGYF1 C11orf16 ZNF8 TUBGCP6 TAF6L HMCN2 PRPF40B LRP2 SIGLEC1 LZTS2 NIN	1.03e-03	1116	167	14	31753913
Pubmed	Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.	SPHK2 TBC1D3 TBC1D3D PACSIN1 IQCN ADGRV1 MAGT1 SNTG1 RAB39B WDR44 TBC1D3F	1.06e-03	750	167	11	11230166
Pubmed	Endothelial Cyp26b1 restrains murine heart valve growth during development.	IL11RA COL6A1 MXRA8 TRIL SCN1B	1.18e-03	163	167	5	35364055
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	POMT2 COL6A1 LAMA3 PIGT EDEM1	1.21e-03	164	167	5	32409323
Pubmed	Mitochondrial reactive oxygen species enable proinflammatory signaling through disulfide linkage of NEMO.	DUOX2 NOX1	1.23e-03	11	167	2	30755476
Pubmed	Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1.	BMP10 VCAN	1.23e-03	11	167	2	37254794
Pubmed	Zinc transporter Slc39a8 is essential for cardiac ventricular compaction.	BMP10 VCAN	1.23e-03	11	167	2	29337306
Pubmed	CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma.	HLA-DQB2 SIGLEC1	1.23e-03	11	167	2	37572655
Pubmed	An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity.	RELB SIGLEC1	1.23e-03	11	167	2	35148840
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RALGDS RBBP5 NOL6 MIB2 GIGYF1 NOL9 JMJD1C CHTF18 EDEM1 PPP6R2	1.25e-03	650	167	10	38777146
Pubmed	Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.	GABRP PGGHG LAMA3 TRIL	1.30e-03	98	167	4	19834535
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	POMT2 DNAH10 TRO IQCN SNED1	1.35e-03	168	167	5	30631154
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	MMP21 BMP10 PKD1 LRP2	1.41e-03	100	167	4	25807483
Pubmed	AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan.	POMT2 FKRP	1.47e-03	12	167	2	24256719
Pubmed	Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis.	HLA-DQB2 TICAM1	1.47e-03	12	167	2	22036947
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	RBBP5 NOL6 NLRP1 USP19 MAP3K5 UBASH3B	1.57e-03	257	167	6	30945288
Pubmed	Fukutin-related protein alters the deposition of laminin in the eye and brain.	FKRP LAMA3	1.73e-03	13	167	2	21900571
Pubmed	Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.	KDM5C KDM5D	1.73e-03	13	167	2	14660691
Pubmed	Establishment of fetomaternal tolerance through glycan-mediated B cell suppression.	HLA-DQB2 SIGLEC1	1.73e-03	13	167	2	35236989
Pubmed	Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development.	NR1D1 KANK3	1.73e-03	13	167	2	25681390
Pubmed	Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.	KDM5C KDM5D	1.73e-03	13	167	2	24619213
Pubmed	CD40 Mediates Maturation of Thymic Dendritic Cells Driven by Self-Reactive CD4+ Thymocytes and Supports Development of Natural Regulatory T Cells.	HLA-DQB2 TICAM1	1.73e-03	13	167	2	29321275
Pubmed	Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.	TICAM1 SIGLEC1	2.01e-03	14	167	2	32515732
Pubmed	The genetics of NOD-like receptors in Crohn's disease.	NLRP1 NLRP5	2.01e-03	14	167	2	20403135
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	9.46e-12	149	167	11	chr17q12
Cytoband	17q12	TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F	3.25e-05	99	167	5	17q12
Cytoband	Xp11.22-p11.21	TRO KDM5C	7.85e-05	4	167	2	Xp11.22-p11.21
Cytoband	11p15.5	B4GALNT4 PGGHG PIDD1 LMNTD2	9.39e-04	118	167	4	11p15.5
GeneFamily	RAB, member RAS oncogene GTPases	RAB4B RAB30 RAB39B RAB37 RAB4A	3.76e-05	65	105	5	388
GeneFamily	Immunoglobulin like domain containing	IL11RA SDK2 MYOM3 TMEM81 HMCN2 SCN1B VSIG10L	1.33e-04	193	105	7	594
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5C KDM5D JMJD1C	3.53e-04	24	105	3	485
GeneFamily	Fibrinogen C domain containing	ANGPT2 FCN2 FIBCD1	3.99e-04	25	105	3	554
GeneFamily	WD repeat domain containing	SEH1L DCAF6 RBBP5 NBEAL2 ATG16L2 WDR44 TBL1X	8.43e-04	262	105	7	362
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05	SPHK2 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	1.82e-09	90	163	10	PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	COL6A1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D PACSIN1 LMNTD2 CCDC57 TBC1D3C TBC1D3B GSTT1 SNAPC4 TBC1D3G TBC1D3K TBC1D3F	4.79e-09	281	163	15	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	COL6A1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D PACSIN1 LMNTD2 CCDC57 TBC1D3C TBC1D3B GSTT1 SNAPC4 TBC1D3G TBC1D3K TBC1D3F	4.79e-09	281	163	15	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05	B4GALNT4 TBC1D3 TBC1D3H TBC1D3L PGGHG TBC1D3D SYNM PACSIN1 TBC1D3C TBC1D3B GSTT1 TBC1D3G TBC1D3K TBC1D3F	5.74e-09	242	163	14	PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	IL11RA RALGDS ASXL1 SDK2 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TRO MXRA8 PIDD1 LMNTD2 NLRP1 MIB2 CREG1 ARHGEF17 TBC1D3C TBC1D3B TUBGCP6 PKD1 KCNK10 LRP2 GREB1 DOT1L PPP6R2 TBC1D3G ATG16L2 TBC1D3K TBC1D3F NIN	7.16e-07	1466	163	30	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D PACSIN1 TBC1D3C TBC1D3B GSTT1 TBC1D3G TBC1D3K TBC1D3F	8.08e-07	213	163	11	PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D PACSIN1 TBC1D3C TBC1D3B GSTT1 TBC1D3G TBC1D3K TBC1D3F	8.08e-07	213	163	11	PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	IL11RA SDK2 TBC1D3 TBC1D3H TBC1D3L TBC1D3D PIDD1 LMNTD2 NLRP1 MIB2 CREG1 ARHGEF17 TBC1D3C TBC1D3B TUBGCP6 KCNK10 LRP2 GREB1 DOT1L TBC1D3G ATG16L2 TBC1D3K TBC1D3F NIN	2.47e-06	1075	163	24	PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L PGGHG TBC1D3D TBC1D3C TBC1D3B VCAN TBC1D3G TBC1D3K TBC1D3F	3.85e-05	320	163	11	PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlas	MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05	GABRP RALGDS SDK2 B4GALNT4 PGGHG SYNM ATOH7 PIDD1 LMNTD2 MIB2 GIGYF1 CCDC57 TAF6L LUC7L CHTF18 ZNF436 PKD1 FIBCD1 LRP2 CARNMT1 GREB1 LZTS2 DOT1L	8.15e-05	1245	163	23	PCBC_ratio_MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05	IL11RA GABRP DCAF6 TBC1D3 STBD1 TBC1D3H TBC1D3L TBC1D3D STARD10 CREG1 TBC1D3C TBC1D3B ITIH1 LGALS8 LRP2 EDEM1 TBC1D3G RAB4A TBC1D3K TBC1D3F	1.63e-04	1049	163	20	PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05
ToppCell	5'-Adult-LymphNode-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	POMT2 IL11RA MXRA8 ARHGEF17 ZNF251 ABHD16B SCN1B DACT3	4.69e-07	183	167	8	d67454baf0cf791a743b51afd1cb25bfb5765385
ToppCell	5'-Adult-LymphNode-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	POMT2 IL11RA MXRA8 ARHGEF17 ZNF251 ABHD16B SCN1B DACT3	4.69e-07	183	167	8	e49ac8314b6fe98426b1514ea68d646297b8bc0f
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PHF24 LAMA3 TTYH3 ADGRV1 JMJD1C OTOGL VCAN TBL1X	5.30e-07	186	167	8	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	droplet-Heart-nan-24m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 GSTT1 DACT3 SNTG1	7.01e-07	193	167	8	d08919db9601941569b9a143dad4d8e6f56a4389
ToppCell	Adult-Mesenchymal-chondrocyte-D231\|Adult / Lineage, Cell type, age group and donor	COL6A1 SDK2 SNED1 NOX1 SCN1B PHACTR3 FIBCD1	2.92e-06	164	167	7	2ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRP SDK2 ADGRV1 C1orf198 DHH PHACTR3 RETREG1	4.15e-06	173	167	7	789ab8b2709f4b8728e3733bc72744e9d92ea5ea
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 SDK2 STBD1 MXRA8 SNED1 TRIL NLRP5	5.20e-06	179	167	7	948c2a01ec7a626c68281e6e796a9f0527a88591
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	B3GALT1 SNED1 TRIL NWD2 PHACTR3 KCNK10 DACT3	5.59e-06	181	167	7	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|World / Stress and Cell class	B3GNT9 MXRA8 U2AF1L4 MATN4 NR1D1 PKD1 DACT3	6.23e-06	184	167	7	684d05340a3dfb8aa08b881516a37f9627a10448
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GALT1 COL6A1 SYNM MATN4 RGS16 DHH VCAN	6.45e-06	185	167	7	ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCell	AT1-AT2_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	PGGHG AARD STARD10 LAMA3 C1orf167 TRIL C1orf198	7.17e-06	188	167	7	be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCell	droplet-Lung-immune-endo-depleted\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 MXRA8 NR1D1 GSTT1 TRIL	7.42e-06	189	167	7	c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCell	droplet-Lung-immune-endo-depleted-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 MXRA8 NR1D1 GSTT1 TRIL	7.42e-06	189	167	7	2a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCell	droplet-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA COL6A1 B3GNT9 MXRA8 NR1D1 GSTT1 TRIL	7.42e-06	189	167	7	5a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 MXRA8 NR1D1 GSTT1 TRIL	7.68e-06	190	167	7	9cd147a174017ebda23cc47b6d4552d898acd092
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL6A1 B3GNT9 STBD1 MXRA8 TRIL VCAN PHACTR3	7.95e-06	191	167	7	a05e9a7eb137d804570dd7d8905975d735738767
ToppCell	droplet-Heart-nan-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 GSTT1 DACT3	7.95e-06	191	167	7	1f660ea2841324d13f63e01f1789e606c2843fc4
ToppCell	droplet-Heart-nan-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 GSTT1 DACT3	8.50e-06	193	167	7	0ca0439dfdcb2361ca8d1015fb874a5b5c635d31
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 TRIL VCAN	8.50e-06	193	167	7	b637e1c47a98009e7d19a6daac78f888fd12748f
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 STBD1 MXRA8 SNED1 TRIL VCAN PHACTR3	8.50e-06	193	167	7	8d05805295c5d3aa93aeb38be5fbefa81e1be1f0
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 STBD1 MXRA8 SNED1 TRIL VCAN PHACTR3	8.50e-06	193	167	7	1b2cc627b2aa002b442358bd1188d470e67ce7d9
ToppCell	facs-Heart-RA-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 MXRA8 GSTT1 SCN1B VCAN DACT3	8.80e-06	194	167	7	bc945450b350f597c3ff910d3a14a533d90086a8
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 STBD1 MXRA8 SNED1 TRIL VCAN PHACTR3	9.09e-06	195	167	7	b616ee6f1d878935d293c8e0a8bbc5b4385301f0
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 STBD1 MXRA8 SNED1 TRIL VCAN PHACTR3	9.09e-06	195	167	7	1c1135be421af98cd0077bec1ff2c4158d42aa21
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 B3GNT9 STBD1 MXRA8 SNED1 TRIL VCAN	9.09e-06	195	167	7	598b69032a8441a23749b27863d80f7a1fc82a96
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 MXRA8 GSTT1 SCN1B VCAN DACT3	9.09e-06	195	167	7	690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCell	PND10-Mesenchymal-Mesenchymal_structural\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 STBD1 MXRA8 SNED1 TRIL VCAN PHACTR3	9.09e-06	195	167	7	11d421bbbb71425d59cbdd673e052e00d5f0a768
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 STBD1 MXRA8 SNED1 TRIL VCAN PHACTR3	9.09e-06	195	167	7	1f005ee1da66b539bd200aaa98f46edbbc7f12e4
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 B3GNT9 STBD1 MXRA8 SNED1 TRIL VCAN	9.09e-06	195	167	7	8aa753934debffe5ae4b5eecb6b50c46d17cc3ec
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 STBD1 MXRA8 SNED1 TRIL VCAN PHACTR3	9.09e-06	195	167	7	10f307aef8f4d9e71c501d5bcedb84d3be7a4d1b
ToppCell	PND07-Mesenchymal-Mesenchymal_structural\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 STBD1 MXRA8 SNED1 TRIL VCAN PHACTR3	9.09e-06	195	167	7	2f9a274b26fc528a85f50933ec2f4db1dc9da0ca
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 MXRA8 GSTT1 SCN1B VCAN DACT3	9.09e-06	195	167	7	5c05e2bcea3d5d7ebe6325f7187ccf83301053d8
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 MXRA8 MATN4 NR1D1 VCAN	9.40e-06	196	167	7	59b5b5a0c123d0423abd19c312514849004b903b
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 MXRA8 MATN4 NR1D1 VCAN	9.72e-06	197	167	7	b16add329bb35a558287ede51353010dde5bc029
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRELID1 ZDHHC7 DUOX2 CREG1 CHTF18 SIGLEC1 SPRYD4	9.72e-06	197	167	7	179b56147cfb0a5f53c58615f2612b8ef68c8bb8
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 AARD MXRA8 GSTT1 VCAN	1.00e-05	198	167	7	8f202ed4692ea2c139ff05d4805c704ee4be095c
ToppCell	PBMC-Control-cDC_0\|Control / Compartment, Disease Groups and Clusters	ZDHHC7 NLRP1 TTYH3 CREG1 MTMR11 NBEAL2 VCAN	1.04e-05	199	167	7	ebf03979ef56e978d72db475bb635b43b9cbe402
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	U2AF1L4 LMNTD2 GIGYF1 DHH KANK3 ATG16L2	2.64e-05	155	167	6	a4f2fffa8d0de760c556c3f8f1c91804eedbfa68
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DNAH10 DUOX2 ADGRV1 NWD2 OTOGL SIGLEC1	3.39e-05	162	167	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAM180B MARCHF10 LAMA3 IQCN SNED1 PHACTR3	3.39e-05	162	167	6	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SYNM ADGRV1 SNED1 HMCN2 RAB39B RAB37	3.75e-05	165	167	6	3d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCell	facs-Marrow-B-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RALGDS DCAF6 RAB30 DNAH17 PKD1 RAB37	3.88e-05	166	167	6	13027ae342994db4540e64eb910df1f42b160931
ToppCell	facs-Marrow-B-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RALGDS DCAF6 RAB30 DNAH17 PKD1 RAB37	3.88e-05	166	167	6	b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	RGS16 SNED1 TRIL SCN1B RETREG1 UBASH3B	4.73e-05	172	167	6	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	B3GNT9 DNAH10 PACSIN1 KDM5C ZNF251 EDEM1	5.05e-05	174	167	6	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A1 ARHGEF17 NWD2 HMCN2 VCAN DNAH17	5.55e-05	177	167	6	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	IL11RA GABRP MARCHF10 MYOM3 HMCN2 DHH	5.91e-05	179	167	6	8c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TTYH3 CREG1 SCN1B FIBCD1 ANKDD1B SIGLEC1	6.09e-05	180	167	6	ba4c1fb55e8f1095bea6968417fefcf5f700926b
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 SNED1 NWD2 PHACTR3 KCNK10 DACT3	6.09e-05	180	167	6	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 SNED1 NWD2 PHACTR3 KCNK10 DACT3	6.09e-05	180	167	6	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|(2)_5-FU / Stress and Cell class	B3GNT9 PACSIN1 MXRA8 NR1D1 PKD1 RETREG1	6.28e-05	181	167	6	56ae86072858c156681507aecd1bc6cb0a3372d2
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A1 FAM180B MXRA8 TRIL GALNT8 FAM87A	6.48e-05	182	167	6	d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SDK2 C1orf198 DHH VCAN PHACTR3 RETREG1	6.68e-05	183	167	6	547b1fb9f9940cfc8d6e351d96acc0da44def57e
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A1 AARD MXRA8 TRIL VCAN DACT3	6.68e-05	183	167	6	af8d86f15a549064530d94bd47081daf59d58ecd
ToppCell	Pericytes-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	COL6A1 SYNM MXRA8 ITIH1 OTOGL DACT3	6.88e-05	184	167	6	cd10d351d91a81dd6dc806cb4e0c8d7861c98e0b
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 RALGDS B3GNT9 KCP RAB39B EDEM1	6.88e-05	184	167	6	42cadfdb5d29a50bd7e901ddd14d42b39e8474f0
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	RELB TBC1D3C MAP3K5 VCAN PHACTR3 RETREG1	6.88e-05	184	167	6	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANGPT2 SYNM KCP ARHGEF17 KANK3 ADAMTS14	7.09e-05	185	167	6	a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|390C / Donor, Lineage, Cell class and subclass (all cells)	POMT2 CCDC57 TRMT2B ZNF251 TUBGCP6 CHTF18	7.30e-05	186	167	6	064b6047215597465bb51a8a1547ef5a226552f9
ToppCell	LPS_only-Unknown-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CPNE9 SYNM KCP MMP21 SNTG1	7.33e-05	115	167	5	ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCell	LPS_only-Unknown\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CPNE9 SYNM KCP MMP21 SNTG1	7.33e-05	115	167	5	7a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCell	LPS_only-Unknown-Endothelial-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CPNE9 SYNM KCP MMP21 SNTG1	7.33e-05	115	167	5	c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	POMT2 CCDC57 TRMT2B ZNF251 TUBGCP6 CHTF18	7.75e-05	188	167	6	2c4e791df69a9df29922f9117e5cac7787c129ce
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	POMT2 CCDC57 TRMT2B ZNF251 TUBGCP6 CHTF18	7.75e-05	188	167	6	b1ec7c45aedcc3d22cac898c6a3679e7f8b44c77
ToppCell	Fibroblast-A\|World / shred on cell class and cell subclass (v4)	COL6A1 STBD1 MXRA8 TRIL VCAN DACT3	7.75e-05	188	167	6	6740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 B3GNT9 MXRA8 NR1D1 GSTT1 DACT3	7.98e-05	189	167	6	32e6d6285b258831b965281224ff2aaeecdcb5f5
ToppCell	facs-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 GSTT1	7.98e-05	189	167	6	bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	COL6A1 STBD1 MXRA8 TRIL VCAN DACT3	7.98e-05	189	167	6	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 GSTT1	7.98e-05	189	167	6	40cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 B3GNT9 MXRA8 NR1D1 GSTT1 DACT3	7.98e-05	189	167	6	385ef7bbd76c8047aeecf6542377d4213b5da5db
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 GSTT1	7.98e-05	189	167	6	e76dc36a01d8ad7590b3acc4c46abfcb76857448
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	COL6A1 STBD1 MXRA8 TRIL VCAN DACT3	8.21e-05	190	167	6	1196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCell	droplet-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 GSTT1	8.21e-05	190	167	6	0b7200897b2c389632c9b1ee37e272b811555dbc
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA COL6A1 B3GNT9 MXRA8 NR1D1 GSTT1	8.45e-05	191	167	6	44a9a6768084dafc641ad455b65862bfd4cc0cb9
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 GSTT1	8.45e-05	191	167	6	094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 GSTT1	8.45e-05	191	167	6	8a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A1 B3GNT9 STBD1 MXRA8 ARHGEF17 GSTT1	8.45e-05	191	167	6	c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCell	facs-Lung-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 GSTT1	8.45e-05	191	167	6	ba02cbdfda6a94374a6472eb88499059979af472
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A1 B3GNT9 STBD1 MXRA8 ARHGEF17 GSTT1	8.45e-05	191	167	6	243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCell	droplet-Lung-21m-Mesenchymal\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 GSTT1	8.45e-05	191	167	6	10a9db1caa0fdb51ace8537f42b2c66f7c97e0f5
ToppCell	3'-Distal_airway-Endothelial-Lymphatic_EC\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANGPT2 SYNM PHF24 RGS16 KANK3 ACSM5	8.70e-05	192	167	6	2ec132a1740e865e7cc0f82ffd4772d43f7ac086
ToppCell	3'-Distal_airway-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANGPT2 SYNM PHF24 RGS16 KANK3 ACSM5	8.70e-05	192	167	6	3792c53b5d4b759573e1c7bb89ef9b654c9cbfcd
ToppCell	3'-Distal_airway-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANGPT2 SYNM PHF24 RGS16 KANK3 ACSM5	8.70e-05	192	167	6	64022a47dccd7966777f6741d1c68e298f37ca9d
ToppCell	3'-Distal_airway-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANGPT2 SYNM PHF24 RGS16 KANK3 ACSM5	8.70e-05	192	167	6	f67a88bd039944d3d7a5a4a9f2e053985075155c
ToppCell	droplet-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11RA COL6A1 B3GNT9 MXRA8 NR1D1 GSTT1	8.70e-05	192	167	6	086b47f87283cd41139cd56686011f8b5821b0da
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL6A1 STBD1 MXRA8 TRIL VCAN PHACTR3	8.70e-05	192	167	6	0afb9dbe468e0be442c326e11c5fc0f699b32f23
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 STBD1 MXRA8 GSTT1	8.70e-05	192	167	6	5876ff75e273a48e7ad8236423fb41e4ae4c0a91
ToppCell	E15.5-Mesenchymal\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL6A1 STBD1 AARD MXRA8 TRIL VCAN	8.95e-05	193	167	6	22a9f5b61f197757f72840b9cb849cdb20430e72
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B3GALT1 COL6A1 B3GNT9 STBD1 MXRA8 DACT3	9.21e-05	194	167	6	7826fe5eb254ac032de0d978f39585a40e0b3ee4
ToppCell	droplet-Heart-nan-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 MXRA8 GSTT1 DACT3	9.21e-05	194	167	6	20a0439fa02c5f8107612e34c7ab54120b9b8573
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 B3GNT9 MXRA8 NR1D1 GSTT1 DACT3	9.21e-05	194	167	6	d47e3c7b22444aef0c7a37bc8cd8853b590a56dd
ToppCell	droplet-Heart-nan-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 MXRA8 GSTT1 DACT3	9.47e-05	195	167	6	613bea20c3d82c22a6af4c1a668af6fcf11fec0a
ToppCell	facs-Heart-LA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 MXRA8 GSTT1 VCAN	9.47e-05	195	167	6	79a6e8e6de040ff07539e8901fc407363a50e355
ToppCell	Bronchus_Control_(B.)-Immune-TX-TRAM-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	ANGPT2 HLA-DQB2 ACSM5 SIGLEC1 RAB39B NOP2	9.47e-05	195	167	6	dabf667875ed48fdce4f803f5ead39c71a6df42b
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL6A1 SDK2 AARD MXRA8 TRIL VCAN	9.74e-05	196	167	6	028a06ed92f1c058dcbeacd335625bf529e87a7b
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 B3GNT9 STBD1 MXRA8 TRIL VCAN	9.74e-05	196	167	6	97e26622d9582b092c18ff5b7e957818f99d9631
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 B3GNT9 STBD1 MXRA8 TRIL VCAN	9.74e-05	196	167	6	f429f045ba45e24717963315832150b12a115bfa
ToppCell	droplet-Heart-HEART-1m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 B3GNT9 MXRA8 MATN4 ARHGEF17 NR1D1	9.74e-05	196	167	6	1eb14182ef26e6141f510d397b00bf8a12efda3e
ToppCell	facs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11RA COL6A1 B3GNT9 MXRA8 GSTT1 VCAN	9.74e-05	196	167	6	ad1838dabd043cb140260843e3527d8c7d58850e
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A1 STBD1 MXRA8 SNED1 TRIL VCAN	9.74e-05	196	167	6	14246f00c90741a5f8683f377e22e3a7c99661b9
Disease	Congenital muscular dystrophy	POMT2 COL6A1 FKRP	2.79e-05	12	151	3	cv:C0699743
Disease	carpal tunnel syndrome	HLA-DQB2 ITIH1 MTMR11 VCAN ADAMTS14	9.65e-05	89	151	5	EFO_0004143
Disease	syndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)	KDM5C KDM5D	1.55e-04	4	151	2	DOID:0060809 (implicated_via_orthology)
Disease	MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYE ANOMALIES), TYPE A, 1	POMT2 FKRP	2.58e-04	5	151	2	236670
Disease	Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1	POMT2 FKRP	2.58e-04	5	151	2	cv:C4284790
Disease	Walker-Warburg syndrome (is_implicated_in)	POMT2 FKRP	2.58e-04	5	151	2	DOID:0050560 (is_implicated_in)
Disease	Ovarian cyst	IFNL4 GREB1	2.58e-04	5	151	2	HP_0000138
Disease	SUN domain-containing protein 3 measurement	ITIH1 FCN2	2.58e-04	5	151	2	EFO_0802102
Disease	bacterial infectious disease (implicated_via_orthology)	RELB MAGT1	2.58e-04	5	151	2	DOID:104 (implicated_via_orthology)
Disease	Qualitative or quantitative defects of alpha-dystroglycan	POMT2 FKRP	3.85e-04	6	151	2	cv:C2936406
Disease	autosomal dominant polycystic kidney disease (biomarker_via_orthology)	ANGPT2 LRP2	5.37e-04	7	151	2	DOID:898 (biomarker_via_orthology)
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	HLA-DQB2 RELB JMJD1C ZNF106 ANKDD1B	8.93e-04	144	151	5	EFO_0004611, EFO_0020943
Disease	primary bacterial infectious disease (implicated_via_orthology)	DUOX2 DHH	9.15e-04	9	151	2	DOID:0050338 (implicated_via_orthology)
Disease	Generalized Epilepsy with Febrile Seizures Plus	ADGRV1 SCN1B	9.15e-04	9	151	2	C3502809
Disease	intracranial aneurysm (is_implicated_in)	VCAN PKD1	1.66e-03	12	151	2	DOID:10941 (is_implicated_in)
Disease	salicylurate measurement	B3GALT1 CHTF18	1.96e-03	13	151	2	EFO_0010532
Disease	membranous glomerulonephritis (biomarker_via_orthology)	MAP3K5 LRP2	2.27e-03	14	151	2	DOID:10976 (biomarker_via_orthology)
Disease	MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K	POMT2 FKRP	2.27e-03	14	151	2	C1836373
Disease	alpha-Dystroglycanopathies	POMT2 FKRP	2.27e-03	14	151	2	C2936406
Disease	Fukuyama Type Congenital Muscular Dystrophy	POMT2 FKRP	2.27e-03	14	151	2	C0410174
Disease	Muscle eye brain disease	POMT2 FKRP	2.27e-03	14	151	2	C0457133
Disease	Muscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 1	POMT2 FKRP	2.27e-03	14	151	2	C4284790
Disease	Walker-Warburg congenital muscular dystrophy	POMT2 FKRP	2.61e-03	15	151	2	C0265221
Disease	liver neoplasm	HLA-DQB2 IFNL4	2.61e-03	15	151	2	EFO_1001513
Disease	syndromic intellectual disability (implicated_via_orthology)	KDM5C KDM5D	2.98e-03	16	151	2	DOID:0050888 (implicated_via_orthology)
Disease	gastroparesis	HLA-DQB2 SNTG1	2.98e-03	16	151	2	EFO_1000948
Disease	obsolete aging	NLRP1 AXIN1 LUC7L ZNF106 SNTG1 UBASH3B	3.22e-03	279	151	6	GO_0007568
Disease	muscular dystrophy (is_implicated_in)	POMT2 FKRP	3.36e-03	17	151	2	DOID:9884 (is_implicated_in)
Disease	triglycerides in small VLDL measurement	DNAH10 JMJD1C KANK3	3.81e-03	61	151	3	EFO_0022145
Disease	transitional cell carcinoma (is_marker_for)	ANGPT2 RELB GSTT1	4.17e-03	63	151	3	DOID:2671 (is_marker_for)
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	RELB JMJD1C ZNF106 ANKDD1B	4.19e-03	127	151	4	EFO_0008595, EFO_0020947
Disease	Sarcomatoid Renal Cell Carcinoma	KDM5C PIDD1 FPGT GSTT1	4.30e-03	128	151	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	KDM5C PIDD1 FPGT GSTT1	4.30e-03	128	151	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	KDM5C PIDD1 FPGT GSTT1	4.30e-03	128	151	4	C1266044
Disease	Papillary Renal Cell Carcinoma	KDM5C PIDD1 FPGT GSTT1	4.30e-03	128	151	4	C1306837
Disease	Renal Cell Carcinoma	KDM5C PIDD1 FPGT GSTT1	4.30e-03	128	151	4	C0007134
Disease	CCL4 measurement	TBC1D3 TBC1D3F	4.65e-03	20	151	2	EFO_0004751
Disease	polymyositis	SDK2 HLA-DQB2	4.65e-03	20	151	2	EFO_0003063
Disease	keratoconus	COL6A1 PIDD1 ZNF106	4.75e-03	66	151	3	MONDO_0015486
Disease	phospholipids:total lipids ratio, intermediate density lipoprotein measurement	HLA-DQB2 JMJD1C ZNF106	4.95e-03	67	151	3	EFO_0008595, EFO_0020946

Protein segments in the cluster

Peptide	Gene	Start	Entry
TAVGRSEVWFRFNEG	CHTF18	946	Q8WVB6
AAAREEQSWTGVEAT	AARD	86	Q4LEZ3
FATWREAQEVAAGAQ	C1orf167	1061	Q5SNV9
QAVTGSRDRTVKEWD	ATG16L2	436	Q8NAA4
DWEERQTSGRITEEF	VCAN	621	P13611
EEVEVQFSAGRWGSA	CARNMT1	26	Q8N4J0
FDARQAIRETWGDEN	B3GALT1	91	Q9Y5Z6
DGARGVIEWQQSRFE	ADGRV1	2956	Q8WXG9
GWTIIQRREDGSVDF	ANGPT2	321	O15123
FVASGRRWVALTESD	ACSM5	251	Q6NUN0
RWFEEASEVAQSNRG	DCAF6	351	Q58WW2
GDFLSEEWRERIANT	DOT1L	221	Q8TEK3
AAQSWRERLADGEFT	ASXL1	316	Q8IXJ9
GSSVEWQEDFRELFR	ADAMTS14	131	Q8WXS8
VAFRWDDVRAVGRSS	ABHD16B	31	Q9H3Z7
ENTSAVFFWRRDTGQ	NWD2	1251	Q9ULI1
QIWDTAGQERFRSIT	RAB39B	61	Q96DA2
QIWDTAGQERFRSIT	RAB30	61	Q15771
LQIWDTAGQERFRSV	RAB37	81	Q96AX2
IWDTAGQERFRSVTR	RAB4A	66	P20338
IWDTAGQERFRSVTR	RAB4B	61	P61018
EDISVVFSRASWEGR	RELB	331	Q01201
VFSRASWEGRADFSQ	RELB	336	Q01201
SWEGRADFSQADVHR	RELB	341	Q01201
DRSWFQDGRARTVSD	IQCN	1016	Q9H0B3
FEGRRTNEINEVLSW	MSL3P1	341	P0C860
DWAGDVTRGQRSQEE	ARHGEF17	621	Q96PE2
RAAGDWTENLIRAFE	NOX1	356	Q9Y5S8
DWREGARQVSRAAAA	NOL9	61	Q5SY16
DEVAAGRRAWTDGFE	ESPNL	906	Q6ZVH7
VRVSARDFLDAGTWS	IL11RA	291	Q14626
VFTDGRSQDDISVWA	MATN4	496	O95460
EQRDSFEGERLAWQA	LZTS2	591	Q9BRK4
FSAEQIARWIADRTD	MAGT1	161	Q9H0U3
FSRERASREESWESG	LUC7L	326	Q9NQ29
QSWDDRGERRFEKSA	GIGYF1	156	O75420
VPSGDFSREWAEAQR	LAMA3	1961	Q16787
WTELAGCTADFRNRD	LMAN2	196	Q12907
WNVVDVNSAGERSRE	GREB1	1651	Q4ZG55
VFSWRDQAVLRQDGV	ITIH1	761	P19827
RNSFLQESWGEEERN	LGALS8	241	O00214
ARGWRVSTVNERFDV	MTMR11	211	A4FU01
SNSAGVDAWEVELRV	HMCN2	1231	Q8NDA2
TGFALAWDDRNCRDV	HMCN2	4656	Q8NDA2
WAQSSGNADARVEEI	CELF2-AS1	36	Q8N7Q2
CVAVGDEARSERWES	JMJD1C	16	Q15652
RAESFDTWANKVRVA	KDM5D	756	Q9BY66
SSEEERGAFVQQLWD	DUOX2	721	Q9NRD8
EEASFWKINAERSRG	C1orf198	186	Q9H425
RWFRNDQEETAGVVS	HLA-DQB2	161	P05538
AERVETFLGWETCNR	PLSCR3	91	Q9NRY6
IIEAFGVRATDSRWS	FBXO46	506	Q6PJ61
GSFDTAFDWIRKERN	MMP21	331	Q8N119
EQARWVEVLGFSESS	NLRP1	471	Q9C000
RFQDGAIREAVVWEA	NOL6	591	Q9H6R4
VTWCEFRARLATVGD	TUBGCP6	1691	Q96RT7
AEWKANVTAEFRETR	KCNK10	341	P57789
TGEGFRLEDVDWNSV	LMNTD2	206	Q8IXW0
EEDVRRSFENTAADW	NLRP5	246	P59047
WSAFQNGTDRRVVFD	LRP2	1491	P98164
FREAGGWDVVRAVAE	PGGHG	391	Q32M88
TVEWEAAAFVARGSD	MFSD11	431	O43934
SQWDVLSGDCDQRFR	RBBP5	91	Q15291
FQATSRREAEWGRVA	OR1K1	261	Q8NGR3
RGADAQEDLRWFRST	PACSIN1	276	Q9BY11
GRSGRTVQEIWEDFS	NR1D1	426	P20393
FDVTDAIRRWQKSGS	BMP10	201	O95393
WRSTAEIDAADGRRV	DACT3	476	Q96B18
FTVLGEARGDQVDWS	CSAG1	11	Q6PB30
RNFTAADWGQSRDAE	COL6A1	211	P12109
IRWAESVENFRSQGV	DNAH17	3336	Q9UFH2
DLQRRASFVAVETEW	DHH	246	O43323
GWTVFQRRVDGSVDF	FCN2	141	Q15485
ARNTGWEAATADVVA	GALNT8	261	Q9NY28
EAEATRRAQSSFAWG	AXIN1	551	O15169
ASQEWREFGRTEVID	CPNE9	46	Q8IYJ1
LAEAERFGSERDWVG	ATOH7	96	Q8N100
AAFAQAREWEEARRA	CCDC57	76	Q2TAC2
GDSTFEWVARRAVKA	EDEM1	321	Q92611
EEEALSWGQRNCSFR	IFNL4	51	K9M1U5
EQFGAWFRAVERLSE	RALGDS	621	Q12967
KRDQFWGQETSFERS	MARCHF10	46	Q8NA82
NFEESRDGRVDSWRN	DNAJC8	211	O75937
GWTVFQRREDGSVNF	FIBCD1	281	Q8N539
QRREDGSVNFFRGWD	FIBCD1	286	Q8N539
SDGGAVRLVAQEWFR	KANK3	571	Q6NY19
ITEWRFLARDEGESA	C2orf81	96	A6NN90
ARVARFVTHVSDWGA	CREG1	56	O75629
AEAGSVVDERGFVWE	FKRP	381	Q9H9S5
RDWTDGVLSNIFREI	DNAH10	2161	Q8IVF4
RTAAVWEEIVGESND	SEH1L	81	Q96EE3
RGVDEASADLVVWAR	SDK2	481	Q58EX2
LCEESQQGAWSEFRR	FAM87A	271	P0C7U9
RGEFWDIVAITAADE	FPGT	46	O14772
NDVEFTWLRGNDSVR	GABRP	186	O00591
CRGRWESFVEETLTE	PPP6R2	511	O75170
EVRNARVFGDSWALG	OTOGL	1096	Q3ZCN5
VVVRTRNDNSWGDLE	PIDD1	411	Q9HB75
GDFTVRVAGWNEVSR	PKD1	1521	P98161
DRGDVRVQFNHETRW	MIB2	301	Q96AX9
SEAEERGRWAQVFAL	FAM180B	136	Q6P0A1
WLRVNGADEDTISRF	MAP3K5	1316	Q99683
SSVERGKEREEAWSF	PHACTR3	331	Q96KR7
LATWRQRVEAAVGED	GSTT1	191	P30711
EDFNRALRWSSVEAV	TAF6L	66	Q9Y6J9
EQSVDCRAGLEFERW	RNPEPL1	496	Q9HAU8
EQAVEDARWTAAFNG	TRMT2B	376	Q96GJ1
GGRKAQEEEFRSESW	RPGRIP1	781	Q96KN7
RSFRSECEAEVGWNL	STARD10	31	Q9Y365
RDSCIGVDDRSWVFT	SPRYD4	111	Q8WW59
GTGDSNDFWRIEVVN	POMT2	446	Q9UKY4
DRGSWRDADSRNDQA	SYNM	1486	O15061
KTWGRNTVFRQEEFE	MAP3K21	566	Q5TCX8
ASFEREREGLQSSAW	NIN	736	Q8N4C6
QVEEAAGRAAAAVTW	RETREG1	56	Q9H6L5
WERAFQTATFLEVER	SNTG1	381	Q9NSN8
NDDRGRSGVAWTQEV	KCP	1256	Q6ZWJ8
SDEAAWRERGQVFSV	NBEAL2	1461	Q6ZNJ1
VNSDNSGWTEIRREA	PRELID1	116	Q9Y255
NRFVDTWARDEDTVL	TBC1D3L	326	B9A6J9
AREAAAGIQWSEEET	NOP2	171	P46087
SVVQEESSAGRAAWE	PHF24	66	Q9UPV7
IQFFDTARVDRTRSW	SLC35B1	71	P78383
VAAFWADVDNRRAGD	SNED1	101	Q8TER0
AEDFERRQAVRQTWG	B3GNT9	126	Q6UX72
REDAIDWQRTFSVGA	B4GALNT4	676	Q76KP1
FTDDQIRAIEEQWSG	ANKDD1B	451	A6NHY2
IRAIEEQWSGNESFR	ANKDD1B	456	A6NHY2
GDAANTWVLARREAD	C11orf16	81	Q9NQ32
ASFDSTVRLWDIERG	TBL1X	481	O60907
NRFVDTWARDEDTVL	TBC1D3B	326	A6NDS4
NRFVDTWARDEDTVL	TBC1D3H	326	P0C7X1
RSSQRSDVGWRLFDD	USP19	1176	O94966
RVSDFRELGSRSWED	TICRR	61	Q7Z2Z1
FESGDRSERQWGDLT	ZNF436	96	Q9C0F3
AERITDVALDFWRSG	TOR1A	211	O14656
SGDVAATFQFRTRWD	PIGT	41	Q969N2
AWGFVSDVDIQSERF	SPHK2	336	Q9NRA0
VTRWEECSNRFLETG	STBD1	331	O95210
DAQAWSRFSFEIEAR	TRO	696	Q12816
NRFVDTWARDEDTVL	TBC1D3F	326	A6NER0
RLVARQWAGVDSTED	TICAM1	71	Q8IUC6
EEDERFEGRVVWNGS	SCN1B	81	Q07699
VAWDGAARELVGNRS	TRIL	466	Q7L0X0
TVEAVGADSASVRWA	TRIL	591	Q7L0X0
KFTSVRRDRNDFWEG	WDR44	821	Q5JSH3
LGTAWEEVRERFVCD	PRPF40B	646	Q6NWY9
NRFVDTWARDEDTVL	TBC1D3E	326	A0A087X179
ENRNFSEDVLGWRES	RGS16	51	O15492
RFEISEVNRWSDVKG	SIGLEC1	116	Q9BZZ2
EDGERAVAELSNRWF	U2AF1L4	121	Q8WU68
DFWRERSGEHTQETN	SKOR2	911	Q2VWA4
WRLARGVISTDDEVF	TMEM81	121	Q6P7N7
DNAQAAEFREAWGRE	ZNF251	126	Q9BRH9
TFRDVAVDFTQEEWG	ZNF8	26	P17098
SEADVADRVWFIRDG	ZDHHC7	31	Q9NXF8
FEGSRSAEEIRKFWQ	SNAPC4	271	Q5SXM2
NRFVDTWARDEDTVL	TBC1D3D	326	A0A087WVF3
DWVATIFSRDIRFAN	UBASH3B	241	Q8TF42
ARDAAVLTWDVERGA	VSIG10L	681	Q86VR7
TAGRLARAAVWEVDF	LCMT2	101	O60294
NRFVDTWARDEDTVL	TBC1D3G	326	Q6DHY5
NRFVDTWARDEDTVL	TBC1D3	326	Q8IZP1
NRTVAGVQDRVWDTA	TTYH3	126	Q9C0H2
WEDSRTGREQESVRD	ZNF106	1401	Q9H2Y7
NRFVDTWARDEDTVL	TBC1D3K	326	A0A087X1G2
NDQIDAGTRRWAVEG	UNC45A	536	Q9H3U1
AEQWRFSSAARDDEV	TYSND1	156	Q2T9J0
NRFVDTWARDEDTVL	TBC1D3I	326	A0A087WXS9
NRFVDTWARDEDTVL	TBC1D3C	326	Q6IPX1
RAESFDTWANKVRVA	KDM5C	766	P41229
TAIWEDQNLRESRFG	MUC12	5431	Q9UKN1
VVSESAVSWEAGARA	MXRA8	36	Q9BRK3
RVGFGNDWERTEIAF	MYOM3	101	Q5VTT5