Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

EMILIN2 FBLN5 FBN1

1.88e-0612423GO:0030023
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

EMILIN2 FBLN5 FBN1

3.10e-0614423GO:0097493
GeneOntologyMolecularFunctionextracellular matrix structural constituent

EMILIN2 FBLN5 FBN1 TECTA

6.44e-04188424GO:0005201
MousePhenoabnormal aorta wall morphology

DDR1 FBLN5 FBN1 PLOD1

9.77e-0650384MP:0009866
MousePhenoabnormal aorta morphology

ATMIN DDR1 FBLN5 FBN1 TULP4 PLOD1

2.92e-05225386MP:0000272
DomaincEGF

FBLN5 FBN1

1.62e-0326432IPR026823
DomaincEGF

FBLN5 FBN1

1.62e-0326432PF12662
DomainBROMODOMAIN_1

TRIM33 CECR2

3.28e-0337432PS00633
DomainBromodomain

TRIM33 CECR2

3.45e-0338432PF00439
DomainBROMODOMAIN_2

TRIM33 CECR2

4.01e-0341432PS50014
DomainBROMO

TRIM33 CECR2

4.20e-0342432SM00297
DomainBromodomain

TRIM33 CECR2

4.20e-0342432IPR001487
Domain-

TRIM33 CECR2

4.20e-03424321.20.920.10
DomainFERM_M

MYO15A FERMT1

5.03e-0346432PF00373
DomainFERM_central

MYO15A FERMT1

5.69e-0349432IPR019748
DomainFERM_domain

MYO15A FERMT1

5.69e-0349432IPR000299
DomainFERM_1

MYO15A FERMT1

5.91e-0350432PS00660
DomainFERM_2

MYO15A FERMT1

5.91e-0350432PS00661
DomainFERM_3

MYO15A FERMT1

5.91e-0350432PS50057
DomainBand_41_domain

MYO15A FERMT1

5.91e-0350432IPR019749
DomainB41

MYO15A FERMT1

5.91e-0350432SM00295
DomainTumour_necrosis_fac-like_dom

EMILIN2 TULP4

7.89e-0358432IPR008983
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

EMILIN2 FBLN5 FBN1

6.62e-0532353MM14854
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

EMILIN2 FBLN5 FBN1

1.03e-0437353M27134
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

EMILIN2 FBLN5 FBN1

1.21e-0439353MM14601
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

EMILIN2 FBLN5 FBN1

1.73e-0444353M26969
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

EMILIN2 DDR1 FBLN5 FBN1 PLOD1

4.09e-04258355MM14572
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

EMILIN2 DDR1 FBLN5 FBN1 PLOD1

8.12e-04300355M610
Pubmed

Fibulin-5 interacts with fibrillin-1 molecules and microfibrils.

FBLN5 FBN1

4.69e-06344215790312
Pubmed

DANCE/fibulin-5 promotes elastic fiber formation in a tropoelastin isoform-dependent manner.

FBLN5 FBN1

4.69e-06344219167375
Pubmed

Reversion-inducing cysteine-rich protein with Kazal motifs and MT1-MMP promote the formation of robust fibrillin fibers.

FBN1 RECK

4.69e-06344232730638
Pubmed

Developmental gene expression profiling along the tonotopic axis of the mouse cochlea.

FZD4 TECTA MYO15A

6.05e-062844322808246
Pubmed

A DNA pooling-based case-control study of myopia candidate genes COL11A1, COL18A1, FBN1, and PLOD1 in a Chinese population.

FBN1 PLOD1

9.37e-06444221527992
Pubmed

Corn1: a mouse model for corneal surface disease and neovascularization.

FBN1 HAO1

9.37e-0644428603845
Pubmed

Fibulin-2 and fibulin-5 alterations in tsk mice associated with disorganized hypodermal elastic fibers and skin tethering.

FBLN5 FBN1

9.37e-06444215610515
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

AAK1 SHISA9 ATMIN DDR1 TECTA TULP4 TRIO PLOD1 RECK RALGAPB

1.31e-051489441028611215
Pubmed

Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.

FBLN5 FBN1

1.56e-05544217255108
Pubmed

Differential regulation of elastic fiber formation by fibulin-4 and -5.

FBLN5 FBN1

1.56e-05544219570982
Pubmed

Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.

FBLN5 FBN1

2.34e-05644219349279
Pubmed

Synaptic, transcriptional and chromatin genes disrupted in autism.

TRIO RALGAPB

3.27e-05744225363760
Pubmed

EMILIN proteins are novel extracellular constituents of the dentin-pulp complex.

EMILIN2 FBN1

4.36e-05844232948785
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

EMILIN2 FBLN5 FBN1 PLOD1

5.99e-0516744422159717
Pubmed

Microarray-based detection of CYP1A1, CYP2C9, CYP2C19, CYP2D6, GSTT1, GSTM1, MTHFR, MTRR, NQO1, NAT2, HLA-DQA1, and AB0 allele frequencies in native Russians.

NAT2 ABO

8.54e-051144220373852
Pubmed

Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.

NAT2 ABO

8.54e-051144224586186
Pubmed

Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy.

NAT2 TRIO

1.02e-041244223776197
Pubmed

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.

NAT2 ABO

1.02e-041244225352340
Pubmed

Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome.

TRIM33 MYBL1

1.21e-041344226624618
Pubmed

α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo.

FBLN5 FBN1

1.63e-041544225670798
Pubmed

MicroRNA expression and regulation in mouse uterus during embryo implantation.

VMP1 RECK

1.63e-041544218556655
Pubmed

A primary expression map of the chromosome 15q15 region containing the recessive form of limb-girdle muscular dystrophy (LGMD2A) gene.

UBR1 FBN1

1.86e-04164427633422
Pubmed

A genome-wide association study identifies two new risk loci for Graves' disease.

ABO RBM45

1.86e-041644221841780
Pubmed

Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network.

AAK1 ABO

2.10e-041744225436638
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

AAK1 TRIM33 WASHC4

3.15e-0410444310470851
Pubmed

Transforming growth factor-β signaling in myogenic cells regulates vascular morphogenesis, differentiation, and matrix synthesis.

FBLN5 FBN1

3.56e-042244221979435
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

RNF41 FBLN5 FBN1 WASHC4 PLOD1 RALGAPB

3.56e-0475444633060197
Pubmed

Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice.

NAT2 MYBL1

4.24e-042444224067652
Pubmed

Gene network analysis in a pediatric cohort identifies novel lung function genes.

SHISA9 MED12L

4.24e-042444224023788
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AAK1 MED12L TRIM33 WASHC4 CECR2

5.32e-0452944514621295
Pubmed

Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.

PPP1R16B FBN1

5.38e-042744235894043
Pubmed

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

RNF41 FBLN5 FBN1 WASHC4

5.47e-0429844432353859
Pubmed

ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.

FBLN5 FBN1

6.65e-043044232882513
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

EMILIN2 FBLN5 FBN1

6.74e-0413544328675934
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

EMILIN2 FBLN5 FBN1

9.69e-0415344325037231
Pubmed

Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set.

FBLN5 WASHC4 RALGAPB

1.04e-0315744312466305
Pubmed

Genome-scale RNAi screen for host factors required for HIV replication.

AAK1 FZD4 RNASEL ABO

1.12e-0336144418976975
Cytoband20q11.23

PPP1R16B RALGAPB

5.85e-043744220q11.23
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

MYO15A FERMT1

2.33e-03502621293
GeneFamilyAnkyrin repeat domain containing

PPP1R16B RNASEL ARAP2

4.91e-03242263403
GeneFamilyActins|Deafness associated genes

TECTA MYO15A

1.14e-021132621152
ToppCellwk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FZD4 EMILIN2 FBLN5 FBN1 TRIO

1.41e-06196445eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 FBLN5 FBN1 RECK

2.32e-051694448bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 FBLN5 FBN1 RECK

2.32e-05169444bb43abad2c049b7f4d307737347290e01b3339a3
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 FBLN5 FBN1 RECK

2.32e-051694445f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_MEMP|lymph-node_spleen / Manually curated celltypes from each tissue

MED12L FBN1 ABO FERMT1

2.72e-0517644423a8ec42ebd42c539865a12d09773af90f3f8848
ToppCell3'-Adult-SmallIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MED12L PPP1R16B PIK3AP1 MYBL1

2.84e-05178444da1695a936dbe3ca9ee3fb28ceb60511c47b35f8
ToppCell3'-Adult-SmallIntestine-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MED12L PPP1R16B PIK3AP1 MYBL1

2.84e-05178444580fc1d45b82010c665a313b2e7a21e0116819ef
ToppCellfacs-Skin-nan-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 FBLN5 FBN1 RECK

3.59e-0518944429287525120be2953b76881ba3cfc4379c265e7a
ToppCellfacs-Skin-nan-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 FBLN5 FBN1 RECK

3.59e-051894447150dad9a92a715487c2d8130fa01b752ea69663
ToppCellfacs-Skin-nan-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 FBLN5 FBN1 RECK

3.59e-051894446e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 FBLN5 FBN1 PLOD1

3.82e-05192444beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EMILIN2 FBLN5 FBN1 TRIO

4.14e-05196444ed6047b48b6a96baa6a90c7af784e7c34b32824d
ToppCellmild_COVID-19_(asymptomatic)-CD4+_CTL|World / disease group, cell group and cell class (v2)

AAK1 PPP1R16B ARAP2 MYBL1

4.30e-0519844403c01fc384d46eec55ff730edbab8a3fde618ed8
ToppCellwk_15-18-Mesenchymal-Fibroblast-Adventitial_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FZD4 FBLN5 FBN1 TRIO

4.39e-051994448de6d7b2067b22cb9b5f01aa56a3803aebc4406d
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

AAK1 RNF41 EVC2 TRIO

4.48e-052004441fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCellCOVID-19_Severe-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

FZD4 ERVK13-1 TECTA

2.49e-0412444354b42ffb161eece4ae308782e43a0e0dc360281e
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-|Striatum / BrainAtlas - Mouse McCarroll V32

FZD4 FBN1 CCDC158

3.13e-04134443a3547a68012d879d4dfe80394eace70808722e43
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)|Striatum / BrainAtlas - Mouse McCarroll V32

FZD4 FBN1 CCDC158

3.13e-041344439458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-common_myeloid_progenitor|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MED12L FBN1 FERMT1

3.34e-041374436d90da42dcc06aa895f920218055068f3c76d57d
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPP1R16B FBLN5 RECK

4.27e-041494431328ce0104d40215ee68abfdbf74eb47b87a7b5b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FAM135B ARAP2 MYBL1

4.44e-04151443b545823113a3450c5f841f7de48bf0937593544f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FAM135B ARAP2 MYBL1

4.44e-041514430cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EVC2 ABO RECK

4.52e-04152443aa88084ba1851d879ece82baa516f6b46cbd2eb8
ToppCell367C-Fibroblasts-Fibroblast-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

FBLN5 FBN1 DACH2

4.70e-04154443dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell367C-Fibroblasts-Fibroblast-D|367C / Donor, Lineage, Cell class and subclass (all cells)

FBLN5 FBN1 DACH2

4.70e-041544434bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VMP1 FBLN5 FBN1

4.88e-04156443bb505f639dbcad2b788db62d6084c2cb4e884bec
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l8|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EMILIN2 PIK3AP1 CECR2

4.97e-041574435098675f64342c41c5ca3551b24962d10c83e64d
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPP1R16B ARAP2 MYBL1

5.06e-04158443da060f5b61c7088f700d138b02ea596adacf7d60
ToppCellBac-SEP-Lymphocyte-T_NK-dnT|Bac-SEP / Disease, Lineage and Cell Type

RNASEL EID3 RBM45

5.25e-04160443f5ca49801c981b903a85a64b21ece6b59fe91cbc
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SHISA9 TECTA DACH2

5.35e-041614433b5d7a3dab479c6959a428f3954dedd989900276
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

FZD4 FBLN5 FBN1

5.45e-04162443e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

FZD4 FBLN5 FBN1

5.45e-04162443ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MED12L ARAP2 MYBL1

5.54e-04163443e6213900f56257fe38ac7852351bea0340294be0
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MED12L ARAP2 MYBL1

5.54e-04163443ed7319185c1ec384444309bb8be95691a0c2091c
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MED12L ARAP2 MYBL1

5.54e-04163443ef35d7ff09aa364734fea7fdaab6260c0a3fbf09
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBLN5 OTUD5 MYBL1

5.74e-04165443cca3ba9d7d30404e3e683b8cfd500c348a4974b9
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MED12L PPP1R16B PIK3AP1

5.74e-041654438b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SHISA9 FBLN5 FBN1

5.74e-041654434e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MED12L ATMIN EID3

5.74e-04165443c39f0479955c4e23921f7a450d3bc251a002200f
ToppCellsevere_COVID-19-gd_T|severe_COVID-19 / disease group, cell group and cell class (v2)

AAK1 TECTA MYBL1

5.74e-0416544349f31173da71c1841616d69b7062852ad7a5090f
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

SHISA9 FAM135B ARAP2

5.74e-041654436ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAT2 ABO CECR2

5.85e-04166443c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

MED12L FBN1 ABO

5.85e-04166443a853005a5587d42daecdf2e23a93109919021a4f
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Trm_gut_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ARAP2 MYBL1 FERMT1

5.95e-0416744369de7d7fc69d699eab03dfea84fdb54263aa5a47
ToppCellHealthy_donor-HSPC|World / disease group, cell group and cell class (v2)

MED12L ABO FERMT1

5.95e-0416744370630ebdfee8171d625811844f8a7c94736d101e
ToppCellmild_COVID-19-HSPC|mild_COVID-19 / disease group, cell group and cell class (v2)

MED12L FBN1 FERMT1

6.05e-0416844390b33962adb77d8326dee403712118398b4d1315
ToppCellLA-16._Neuronal|World / Chamber and Cluster_Paper

SHISA9 FAM135B ARAP2

6.05e-041684432fd1fd2a16ac1c5eb028f93cc3a2477c7747693e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SHISA9 FBN1 DACH2

6.05e-04168443f3879a8e11eaf866f37c52e67021be43f0b8784a
ToppCellBronchial_Biopsy-Immune-T_and_NK|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

FZD4 FBLN5 RECK

6.05e-04168443435b2f238fbb3f50427e8cdecf2220615015153c
ToppCellLA-16._Neuronal|LA / Chamber and Cluster_Paper

SHISA9 FAM135B ARAP2

6.05e-04168443c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC|GW23 / Sample Type, Dataset, Time_group, and Cell type.

RBM45 PLOD1 FERMT1

6.16e-04169443b1611e61f635f8f9b87250e026ad30999cbee041
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

SHISA9 FAM135B ARAP2

6.16e-04169443a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related|GW23 / Sample Type, Dataset, Time_group, and Cell type.

RBM45 PLOD1 FERMT1

6.16e-0416944329db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCell3'-Adult-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MED12L PPP1R16B MYBL1

6.16e-04169443203971cceeba150d0e8891c92662545e84c77837
ToppCellmild_COVID-19-HSPC|World / disease group, cell group and cell class (v2)

MED12L FBN1 FERMT1

6.26e-0417044385c476e0bc496445e868a88849960598d97bdea2
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

MED12L ABO FERMT1

6.37e-041714433ecd0a074344179c57eb2d9a857ba594904d00fa
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPP1R16B ARAP2 MYBL1

6.37e-04171443f16cb64b8844c2668922c786888efaa9f873afcc
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AAK1 RBM45 RALGAPB

6.37e-041714432e7cc311005958af52f39ca6c310c85b43a85aaf
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AAK1 RBM45 RALGAPB

6.37e-041714434b599f953c8e5b947b2c8bbbf7fe6f9dc388e336
ToppCellHealthy_donor-HSPC|Healthy_donor / disease group, cell group and cell class (v2)

MED12L ABO FERMT1

6.48e-04172443bc7549faadfc92c683c0e26bea380458706774b5
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TULP4 ARAP2 FERMT1

6.48e-041724431f335ccb92b22d0412954e8fc3af212f96410b67
ToppCelldroplet-Liver-nan-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TULP4 ARAP2 FERMT1

6.48e-04172443bb96c896d125e10b71e94e2bdad243899045af5c
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBN1 TECTA TRIO

6.48e-04172443e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MED12L PIK3AP1 MYBL1

6.59e-04173443b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCellLV-17._Lymphocyte|World / Chamber and Cluster_Paper

PPP1R16B ARAP2 MYBL1

6.59e-04173443212f013ff761cbab24a537071739867c08c402a4
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors|lymph-node_spleen / Manually curated celltypes from each tissue

MED12L ABO FERMT1

6.70e-041744436d9bdf4d28ff8ebb66ffd1ccdd6a4fe9440a83f3
ToppCellsevere_COVID-19-HSPC|severe_COVID-19 / disease group, cell group and cell class (v2)

MED12L FBN1 FERMT1

6.70e-041744436d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPP1R16B ARAP2 MYBL1

6.93e-041764436b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic-B_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R16B CECR2 ARAP2

6.93e-04176443318dc722b95e269002fb01a0feb91c0c8539e150
ToppCellfacs-MAT-Fat-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R16B CRBN ARAP2

6.93e-04176443359a57aea89d8e6776eaefb0c3553a0dbcad5e58
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-HSC-MPP|lymph-node_spleen / Manually curated celltypes from each tissue

MED12L ABO FERMT1

6.93e-0417644332ed5623b8809b9f1aaf7a42dff9807d9376e9c2
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBLN5 ABO TECTA

6.93e-0417644372a2a01618ce836bc843395d5095e9090759b4a6
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic-B_cell-B_cell_of_the_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R16B CECR2 ARAP2

6.93e-04176443f6891006d816309edabe75b2abf60675f2958e55
ToppCellsevere_COVID-19-HSPC|World / disease group, cell group and cell class (v2)

MED12L FBN1 FERMT1

7.04e-04177443289f6aed6f054b04b01659434d8c8b467d1bf5dd
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPP1R16B ARAP2 MYBL1

7.04e-041774439edfb50856f5e10672ab194ce0076d6a190e64de
ToppCellcontrol-Others-CD34+_GATA2+_cells|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FBN1 ABO FERMT1

7.16e-041784432120bd3e099b0b271bf079db9827a2f3eee2f909
ToppCell3'_v3-Lung-Hematopoietic_progenitors|Lung / Manually curated celltypes from each tissue

MED12L ABO FERMT1

7.16e-04178443c7895ba2e2e93b26da91faa2a3bf9d070dd4c3bd
ToppCell356C-Fibroblasts-Fibroblast-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

FBLN5 FBN1 FERMT1

7.16e-04178443a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell356C-Fibroblasts-Fibroblast-E|356C / Donor, Lineage, Cell class and subclass (all cells)

FBLN5 FBN1 FERMT1

7.16e-04178443371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCell3'_v3-Lung-Hematopoietic_progenitors-HSC-MPP|Lung / Manually curated celltypes from each tissue

MED12L ABO FERMT1

7.27e-041794432c03b82ec9b4dee2501752b8d83e7028f0aaed77
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

FZD4 PPP1R16B MYBL1

7.27e-04179443d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MED12L FBN1 ABO

7.39e-04180443f598bb9df0d784120847fada2d9a2a88b8b68cd1
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Lymphocytic-B_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R16B PIK3AP1 ARAP2

7.39e-0418044314ca8875af7cceead88fec147a4c0ef4d5a41f26
ToppCellRA-16._Neuronal|RA / Chamber and Cluster_Paper

SHISA9 FAM135B ARAP2

7.39e-041804435842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

AAK1 VMP1 MYBL1

7.39e-04180443d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MED12L FBN1 ABO

7.39e-04180443b4fa047f271c7b56940bdc85c912f50aa5b5ca82
ToppCellCOVID-19-kidney-NK|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPP1R16B ARAP2 MYBL1

7.51e-041814438906ee8a7a1616dfe8c3b5c73988416641213629
ToppCellBLOOD-unannotated|BLOOD / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

AAK1 FBLN5 ABO

7.51e-041814433a5c0c701fc2c078e1504bbf88ae708546cc74a3
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBLN5 ABO TECTA

7.51e-0418144308f44323bf71b6004a921bbc969c954c75feeb66
ToppCellfacs-Kidney-nan-24m-Mesenchymal-kidney_interstitial_fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 FBLN5 FBN1

7.51e-041814430ec9621a078d004bbd25a587757d24b5cf162959
ToppCellLV-17._Lymphocyte|LV / Chamber and Cluster_Paper

PPP1R16B ARAP2 MYBL1

7.51e-0418144381fafa69c8c240250a667a5f3b321e8be1b9a288
ToppCellRA-16._Neuronal|World / Chamber and Cluster_Paper

SHISA9 FAM135B ARAP2

7.51e-041814437d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PPP1R16B PIK3AP1 ARAP2

7.51e-0418144351e4d6bfdbf414d8e30aee2e6f7492f4f7f54373
ToppCell5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHISA9 PIK3AP1 ABO

7.51e-04181443c7a220891567c7539ad5a9ac9db375f0de08ea00
ToppCellfacs-Kidney-nan-24m-Mesenchymal-kidney_interstitial_fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 FBLN5 FBN1

7.51e-04181443c7f5aedcb74c21fb587a95a16d700e2a38a380ee
ToppCellfacs-GAT-Fat-3m-Lymphocytic-T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R16B DACH2 ARAP2

7.63e-04182443751bd3e3b49de961523e98197688a05c998c121a
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR1 CECR2 FERMT1

7.63e-041824438a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR1 CECR2 FERMT1

7.63e-04182443e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

MED12L DACH2 FERMT1

7.75e-0418344300a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 FBLN5 FBN1

7.75e-041834435cfcd589a480e67654d3d94e71916f122150db10
DiseaseArachnodactyly

FZD4 FBN1

1.18e-054422C0003706
Diseaseleukemia (is_implicated_in)

NAT2 ABO

1.53e-0413422DOID:1240 (is_implicated_in)
Diseasecancer biomarker measurement

ABO FAM135B

2.05e-0415422EFO_0005127
DiseaseProstatic Neoplasms

NAT2 DDR1 FBLN5 RNASEL HAO1 ABO

2.24e-04616426C0033578
DiseaseMalignant neoplasm of prostate

NAT2 DDR1 FBLN5 RNASEL HAO1 ABO

2.24e-04616426C0376358
Diseasemethylcobalamin deficiency type cblE, brain serotonin transporter measurement

NAT2 TRIO

2.34e-0416422EFO_0004569, MONDO_0009354
Diseasefree cholesterol:total lipids ratio, intermediate density lipoprotein measurement

NAT2 MAU2 ABO

2.53e-0486423EFO_0008595, EFO_0020945
Diseasesystemic scleroderma (is_implicated_in)

NAT2 FBN1

5.35e-0424422DOID:418 (is_implicated_in)
DiseaseIniencephaly

NAT2 CECR2

7.30e-0428422C0152234
DiseaseTethered Cord Syndrome

NAT2 CECR2

7.30e-0428422C0080218
DiseaseSpinal Cord Myelodysplasia

NAT2 CECR2

7.30e-0428422C0344479
DiseaseExencephaly

NAT2 CECR2

7.30e-0428422C0266453
DiseaseNeurenteric Cyst

NAT2 CECR2

7.30e-0428422C0027806
DiseaseAcrania

NAT2 CECR2

7.30e-0428422C0702169
DiseaseDiastematomyelia

NAT2 CECR2

7.30e-0428422C0011999
DiseaseCraniorachischisis

NAT2 CECR2

7.84e-0429422C0152426
DiseaseNeural Tube Defects

NAT2 CECR2

8.39e-0430422C0027794
Diseasepyridoxate measurement

EMILIN2 RNASEL

8.96e-0431422EFO_0010527
Diseaseessential tremor

NAT2 FBLN5 TRIO

9.64e-04136423EFO_0003108
Diseasesensorineural hearing loss (is_implicated_in)

TECTA MYO15A

1.02e-0333422DOID:10003 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
GDRVMNLQHRMQLQC

ERVK13-1

361

Q9NX77
TRACHQAMMVDQANG

ABO

281

P16442
MDFCRGGQVVNLMNQ

AAK1

126

Q2M2I8
QAMQVHCNNMHTLGA

DDR1

281

Q08345
DGMNEMYLRCDHENQ

FERMT1

446

Q9BQL6
MAGEGDQQDAAHNMG

CRBN

1

Q96SW2
FCLQMQEVQGDRMHL

ARAP2

1046

Q8WZ64
MEGLQFGNECLNKMH

CHMP6

101

Q96FZ7
GNSMGMTNLERDQCH

PIK3AP1

491

Q6ZUJ8
CMGNSQHQGRQMGAA

CCDC74B

241

Q96LY2
GNTNTNECRMVDMHG

DACH2

61

Q96NX9
RCQEEGLGHFQAVMM

CECR2

1411

Q9BXF3
RAMEEMHGQCLGPND

RBM45

81

Q8IUH3
GQSGLLENCMEMHCI

RECK

561

O95980
MNVCMGHQDAGRIND

MED12L

1016

Q86YW9
QAVCQHRLMQAMGRA

MYO15A

2181

Q9UKN7
MNVNQMGEGNDSSCH

EID3

286

Q8N140
CVGATAMQRMAHVDG

HAO1

76

Q9UJM8
MRQEVHGCFAQMDRS

EVC2

851

Q86UK5
MANADARNMGADLCR

PLOD1

356

Q02809
QQMIADIHCMIAAGQ

PPP1R16B

206

Q96T49
QNDHNHMCMEGPGDE

FZD4

151

Q9ULV1
PTDDHVQMDQAGMCG

ATMIN

501

O43313
VAMAEDRGNGLMEHC

C2CD3

991

Q4AC94
VNGGNNCMDMRRSLC

FBN1

1681

P35555
NMHCGQAMELGLEAI

NAT2

41

P11245
QKEMSNCRAGENAGM

EMILIN2

626

Q9BXX0
ECQGQMERQMAAIQG

CCDC158

441

Q5M9N0
EPGENVATQNHMDMC

FAM135B

481

Q49AJ0
EACRGDMMCVNQNGG

FBLN5

51

Q9UBX5
CENQHMGDDMVQEPG

RNF41

291

Q9H4P4
ACGNAMDAHEAAQMH

MAU2

551

Q9Y6X3
MRIQHNEGAMECQFN

MYBL1

396

P10243
NNCHGNHIEMQAMAE

OTUD5

276

Q96G74
QRGNMNCGAFQAHQM

TRIM33

576

Q9UPN9
MGADVNACDNMGRNA

RNASEL

191

Q05823
ADVMRPQGHCNTDHM

SHISA9

191

B4DS77
MCDNVHIQKMQGDGY

TECTA

1676

O75443
TADGQVIVMDCHGRM

TULP4

186

Q9NRJ4
CMQGMEEIRRQVGQH

UBR1

511

Q8IWV7
CQMEMGGGENNLKSH

RALGAPB

701

Q86X10
ASMVEGDCQIQMGRF

WASHC4

126

Q2M389
RCNDMMNVGRLQGFD

TRIO

2141

O75962
MAENGKNCDQRRVAM

VMP1

1

Q96GC9