Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionkinase activity

CDC42BPG FLT4 RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B PIK3R3 TRRAP CDC42BPB STK32A MET TNNI3K BRD2 IKBKE STKLD1 ADPGK

1.34e-0876410419GO:0016301
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

CDC42BPG FLT4 RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B PIK3R3 CDC42BPB STK32A MET TNNI3K BRD2 IKBKE STKLD1 ADPGK

2.47e-0870910418GO:0016773
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

CDC42BPG FLT4 RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B PIK3R3 TRRAP CDC42BPB STK32A MET TNNI3K TRNT1 BRD2 IKBKE STKLD1 ADPGK

6.75e-0893810420GO:0016772
GeneOntologyMolecularFunctionprotein kinase activity

CDC42BPG FLT4 RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B CDC42BPB STK32A MET TNNI3K BRD2 IKBKE STKLD1

8.30e-0860010416GO:0004672
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

CDC42BPG RPS6KA4 CDC42BPA KALRN SPEG DAPK2 STK32B CDC42BPB STK32A TNNI3K BRD2 IKBKE STKLD1

5.59e-0744610413GO:0004674
GeneOntologyMolecularFunctionprotein serine kinase activity

CDC42BPG RPS6KA4 CDC42BPA KALRN SPEG DAPK2 STK32B CDC42BPB STK32A TNNI3K

2.00e-0536310410GO:0106310
GeneOntologyMolecularFunctionhistone deacetylase activity

HDAC9 HDAC3 HDAC1

2.57e-04241043GO:0004407
GeneOntologyMolecularFunctionprotein decrotonylase activity

HDAC3 HDAC1

2.66e-0451042GO:0160008
GeneOntologyMolecularFunctionhistone decrotonylase activity

HDAC3 HDAC1

2.66e-0451042GO:0160009
GeneOntologyMolecularFunctionprotein lysine deacetylase activity

HDAC9 HDAC3 HDAC1

2.90e-04251043GO:0033558
GeneOntologyMolecularFunctionmagnesium ion binding

CDC42BPG RPS6KA4 CDC42BPA WEE1 CDC42BPB ADCY2 GCLC

3.12e-042471047GO:0000287
GeneOntologyMolecularFunctionL-leucine binding

SESN3 SESN1

5.55e-0471042GO:0070728
GeneOntologyMolecularFunctiondeacetylase activity

HDAC9 HDAC3 HDAC1

1.18e-03401043GO:0019213
GeneOntologyCellularComponentGATOR2 complex

SZT2 SESN3 SESN1

2.55e-05121043GO:0061700
GeneOntologyCellularComponentSeh1-associated complex

SZT2 SESN3 SESN1

6.39e-05161043GO:0035859
GeneOntologyCellularComponenthistone deacetylase complex

HDAC9 TRRAP HDAC3 HDAC1

8.59e-04851044GO:0000118
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class I

PIK3R3 PIK3R2

8.63e-0491042GO:0097651
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class IA

PIK3R3 PIK3R2

8.63e-0491042GO:0005943
DomainKinase-like_dom

CDC42BPG FLT4 RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B WDR81 TRRAP CDC42BPB STK32A MET TNNI3K IKBKE STKLD1

8.83e-0954210517IPR011009
DomainProtein_kinase_ATP_BS

CDC42BPG FLT4 RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B CDC42BPB STK32A MET TNNI3K IKBKE

2.72e-0837910514IPR017441
DomainPROTEIN_KINASE_ATP

CDC42BPG FLT4 RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B CDC42BPB STK32A MET TNNI3K IKBKE STKLD1

4.22e-0845910515PS00107
DomainProt_kinase_dom

CDC42BPG FLT4 RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B CDC42BPB STK32A MET TNNI3K IKBKE STKLD1

9.64e-0848910515IPR000719
DomainPROTEIN_KINASE_DOM

CDC42BPG FLT4 RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B CDC42BPB STK32A MET TNNI3K IKBKE STKLD1

1.07e-0749310515PS50011
DomainMyotonic_dystrophy_kinase_coil

CDC42BPG CDC42BPA CDC42BPB

6.88e-0741053IPR014930
DomainMyotonic_dystrophy_kinase_coil

CDC42BPG CDC42BPA CDC42BPB

6.88e-0741053PD011252
DomainDMPK_coil

CDC42BPG CDC42BPA CDC42BPB

6.88e-0741053PF08826
DomainSer/Thr_kinase_AS

CDC42BPG RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B CDC42BPB STK32A TNNI3K IKBKE

7.83e-0735710512IPR008271
DomainPROTEIN_KINASE_ST

CDC42BPG RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B CDC42BPB STK32A TNNI3K IKBKE

9.07e-0736210512PS00108
DomainPkinase

CDC42BPG RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B CDC42BPB STK32A IKBKE STKLD1

1.55e-0638110512PF00069
DomainS_TKc

CDC42BPG RPS6KA4 CDC42BPA KALRN WEE1 SPEG DAPK2 STK32B CDC42BPB STK32A IKBKE

5.64e-0635910511SM00220
DomainHist_deacetyl

HDAC9 HDAC3 HDAC1

2.76e-05111053PF00850
Domain-

HDAC9 HDAC3 HDAC1

2.76e-051110533.40.800.20
DomainHis_deacetylse_dom

HDAC9 HDAC3 HDAC1

2.76e-05111053IPR023801
DomainHis_deacetylse

HDAC9 HDAC3 HDAC1

2.76e-05111053IPR000286
DomainKELK

CDC42BPA CDC42BPB

3.13e-0521052IPR031597
DomainKELK

CDC42BPA CDC42BPB

3.13e-0521052PF15796
DomainPkinase_C

CDC42BPG RPS6KA4 CDC42BPA CDC42BPB

5.40e-05371054IPR017892
DomainCNH

CDC42BPG CDC42BPA CDC42BPB

6.01e-05141053SM00036
DomainCNH

CDC42BPG CDC42BPA CDC42BPB

7.48e-05151053PF00780
DomainCNH

CDC42BPG CDC42BPA CDC42BPB

7.48e-05151053PS50219
DomainCNH_dom

CDC42BPG CDC42BPA CDC42BPB

7.48e-05151053IPR001180
DomainANK

TRPA1 POTEB2 SHANK3 ANKRD44 TNNI3K ANKRD28 POTEJ POTEB

8.64e-052511058SM00248
DomainPkinase_C

CDC42BPG RPS6KA4 CDC42BPA CDC42BPB

8.96e-05421054PF00433
DomainANK_REPEAT

TRPA1 POTEB2 SHANK3 ANKRD44 TNNI3K ANKRD28 POTEJ POTEB

9.13e-052531058PS50088
DomainSestrin

SESN3 SESN1

9.36e-0531052IPR006730
DomainPI3K_P85_iSH2

PIK3R3 PIK3R2

9.36e-0531052IPR032498
DomainAhpD-like

SESN3 SESN1

9.36e-0531052IPR029032
DomainPA26

SESN3 SESN1

9.36e-0531052PF04636
DomainPI3K_P85_iSH2

PIK3R3 PIK3R2

9.36e-0531052PF16454
Domain-

SESN3 SESN1

9.36e-05310521.20.1290.10
DomainAnkyrin_rpt-contain_dom

TRPA1 POTEB2 SHANK3 ANKRD44 TNNI3K ANKRD28 POTEJ POTEB

9.38e-052541058IPR020683
DomainANK_REP_REGION

TRPA1 POTEB2 SHANK3 ANKRD44 TNNI3K ANKRD28 POTEJ POTEB

9.38e-052541058PS50297
DomainAnkyrin_rpt

TRPA1 POTEB2 SHANK3 ANKRD44 TNNI3K ANKRD28 POTEJ POTEB

1.16e-042621058IPR002110
DomainCRIB

CDC42BPG CDC42BPA CDC42BPB

1.84e-04201053PS50108
DomainHis_deacetylse_1

HDAC3 HDAC1

1.86e-0441052IPR003084
DomainCRIB_dom

CDC42BPG CDC42BPA CDC42BPB

2.13e-04211053IPR000095
DomainAGC-kinase_C

CDC42BPG RPS6KA4 CDC42BPA CDC42BPB

2.77e-04561054IPR000961
DomainAGC_KINASE_CTER

CDC42BPG RPS6KA4 CDC42BPA CDC42BPB

2.77e-04561054PS51285
DomainS_TK_X

CDC42BPG RPS6KA4 CDC42BPA CDC42BPB

2.77e-04561054SM00133
DomainPI3kinase_P85

PIK3R3 PIK3R2

3.10e-0451052IPR001720
DomainVWC

FRAS1 NELL2 CHRD

5.11e-04281053PF00093
DomainVWFC_1

FRAS1 NELL2 CHRD

1.08e-03361053PS01208
DomainBEACH

WDR81 LYST

1.10e-0391052PS50197
DomainBeach

WDR81 LYST

1.10e-0391052PF02138
Domain-

WDR81 LYST

1.10e-03910521.10.1540.10
DomainBeach

WDR81 LYST

1.10e-0391052SM01026
DomainBEACH_dom

WDR81 LYST

1.10e-0391052IPR000409
DomainVWFC_2

FRAS1 NELL2 CHRD

1.26e-03381053PS50184
DomainVWC

FRAS1 NELL2 CHRD

1.26e-03381053SM00214
DomainAnk_2

TRPA1 POTEB2 SHANK3 ANKRD44 ANKRD28 POTEJ

1.36e-032151056PF12796
DomainVWF_dom

FRAS1 NELL2 CHRD

1.69e-03421053IPR001007
DomainAnk

TRPA1 ANKRD44 TNNI3K ANKRD28 POTEJ POTEB

1.83e-032281056PF00023
Domain-

TRPA1 POTEB2 SHANK3 ANKRD44 ANKRD28 POTEJ

2.78e-0324810561.25.40.20
DomainEGF-like_dom

FRAS1 MEP1A NELL2 TENM4 CELSR3 GP2

2.84e-032491056IPR000742
DomainPBD

CDC42BPA CDC42BPB

3.57e-03161052SM00285
DomainPBD

CDC42BPG CDC42BPB

4.03e-03171052PF00786
DomainC1_1

CDC42BPG CDC42BPA CDC42BPB

4.05e-03571053PF00130
DomainIg_I-set

FLT4 NRCAM KALRN SPEG ADGRF5

4.39e-031901055IPR013098
DomainI-set

FLT4 NRCAM KALRN SPEG ADGRF5

4.39e-031901055PF07679
DomainVWC_out

FRAS1 NELL2

5.03e-03191052SM00215
DomainZF_DAG_PE_1

CDC42BPG CDC42BPA CDC42BPB

5.61e-03641053PS00479
DomainZF_DAG_PE_2

CDC42BPG CDC42BPA CDC42BPB

5.61e-03641053PS50081
Pubmed

Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression.

HDAC9 HDAC3 HDAC1

2.75e-083106315711539
Pubmed

Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5.

HDAC9 HDAC3 HDAC1

1.10e-074106310655483
Pubmed

Distinct Roles of HDAC3 in the Core Circadian Negative Feedback Loop Are Critical for Clock Function.

CRY1 HDAC3 HDAC1

5.47e-076106326776516
Pubmed

The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase.

HDAC9 HDAC3 HDAC1

9.55e-077106312032081
Pubmed

Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor.

HDAC9 HDAC3 HDAC1

9.55e-077106311022042
Pubmed

MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion.

CDC42BPG CDC42BPA CDC42BPB

9.55e-077106329162624
Pubmed

POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.

POTEB2 POTEJ POTEB

1.52e-068106312475935
Pubmed

Transcription repressor activity of spleen tyrosine kinase mediates breast tumor suppression.

HDAC9 HDAC3 HDAC1

1.52e-068106316288017
Pubmed

Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.

ATAT1 SHANK3 HDAC3 HDAC1

1.58e-0628106431600191
Pubmed

Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo.

HDAC9 HDAC3 HDAC1

2.28e-069106311466315
Pubmed

Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development.

HDAC9 HDAC3 HDAC1

2.28e-069106315367668
Pubmed

Histone deacetylase 10 regulates DNA mismatch repair and may involve the deacetylation of MutS homolog 2.

HDAC9 HDAC3 HDAC1

2.28e-069106326221039
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

FRAS1 CDC42BPA PDE7A AHCTF1 PIK3R3 CDC42BPB DDOST EFR3A MET BRD2 SLC4A1AP LNPEP PIK3R2 RAB3GAP2 ANKRD28 PCNT ZC3HAV1

2.58e-0614871061733957083
Pubmed

Class II histone deacetylases: versatile regulators.

HDAC9 HDAC3 HDAC1

3.25e-0610106312711221
Pubmed

Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina.

HDAC9 HDAC3 HDAC1

3.25e-0610106328028172
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

HDAC9 PDE7A NRCAM KALRN RAPGEF4 SESN3 SIM2 CDC42BPB TXNDC11 NELL2 BRD2 CELSR3 DHX35 ZNF292 PCNT

8.36e-0612851061535914814
Pubmed

Alcohol-induced serotonergic modulation: the role of histone deacetylases.

HDAC3 HDAC1

9.20e-062106222796363
Pubmed

Interactive Effects of a Combination of the HDAC3 and HDAC9 Genes with Diabetes Mellitus on the Risk of Ischemic Stroke.

HDAC9 HDAC3

9.20e-062106232961570
Pubmed

Histone deacetylases and the immunological network: implications in cancer and inflammation.

HDAC3 HDAC1

9.20e-062106219855430
Pubmed

Cloning and chromosomal localization of human Cdc42-binding protein kinase beta.

CDC42BPA CDC42BPB

9.20e-062106210198171
Pubmed

DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers.

DAPK2 HDAC1

9.20e-062106212087472
Pubmed

HIV-1 Vpr reactivates latent HIV-1 provirus by inducing depletion of class I HDACs on chromatin.

HDAC3 HDAC1

9.20e-062106227550312
Pubmed

MEF-2 function is modified by a novel co-repressor, MITR.

HDAC9 HDAC1

9.20e-062106210487760
Pubmed

Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta.

CDC42BPA CDC42BPB

9.20e-062106218263588
Pubmed

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.

HDAC3 HDAC1

9.20e-062106227109927
Pubmed

Histone deacetylase-1 (HDAC1) is a molecular switch between neuronal survival and death.

HDAC3 HDAC1

9.20e-062106222918830
Pubmed

Sestrins induce natural killer function in senescent-like CD8+ T cells.

SESN3 SESN1

9.20e-062106232231301
Pubmed

Histone deacetylase expression patterns in developing murine optic nerve.

HDAC9 HDAC3 HDAC1

9.77e-0614106325011550
Pubmed

Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin.

HDAC9 HDAC3 HDAC1

9.77e-0614106315601857
Pubmed

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis.

HDAC9 HDAC3 HDAC1

9.77e-0614106315537544
Pubmed

The histone deacetylase 9 gene encodes multiple protein isoforms.

HDAC9 HDAC3 HDAC1

9.77e-0614106312590135
Pubmed

Hdac3 regulates lymphovenous and lymphatic valve formation.

FLT4 HDAC3 HDAC1

1.50e-0516106329035278
Pubmed

Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10.

HDAC9 HDAC3 HDAC1

1.50e-0516106316873063
Pubmed

HDAC family: What are the cancer relevant targets?

HDAC9 HDAC3 HDAC1

2.17e-0518106318824292
Pubmed

Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities.

FRAS1 NRCAM TENM4

2.17e-0518106320602751
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

TCTE1 DAPK2 SESN3 TRRAP ADCY2 STK32A HDAC3 BRD2 GCLC PIK3R2 DHX35 PRMT7 ADPGK HDAC1

2.52e-0512421061430973865
Pubmed

Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo.

HDAC3 HDAC1

2.76e-053106230279482
Pubmed

HDAC1/2 and HDAC3 play distinct roles in controlling adult Meibomian gland homeostasis.

HDAC3 HDAC1

2.76e-053106238679196
Pubmed

CCN5, a novel transcriptional repressor of the transforming growth factor β signaling pathway.

HDAC3 HDAC1

2.76e-053106221262769
Pubmed

Regulation of the HIF-1alpha stability by histone deacetylases.

HDAC3 HDAC1

2.76e-053106217273746
Pubmed

Sestrins are evolutionarily conserved mediators of exercise benefits.

SESN3 SESN1

2.76e-053106231929512
Pubmed

Class I histone deacetylases 1, 2 and 3 are highly expressed in renal cell cancer.

HDAC3 HDAC1

2.76e-053106219099586
Pubmed

Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy.

HDAC3 HDAC1

2.76e-053106218212746
Pubmed

Sestrin1, 2, and 3 are dispensable for female fertility in mice.

SESN3 SESN1

2.76e-053106238297375
Pubmed

Histone deacetylase 1 and 3 regulate the mesodermal lineage commitment of mouse embryonic stem cells.

HDAC3 HDAC1

2.76e-053106225412078
Pubmed

HDAC1/HDAC3 modulates PPARG2 transcription through the sumoylated CEBPD in hepatic lipogenesis.

HDAC3 HDAC1

2.76e-053106218619497
Pubmed

Role of the LXCXE binding site in Rb function.

HDAC3 HDAC1

2.76e-053106210958676
Pubmed

The Cohesin loading factor NIPBL recruits histone deacetylases to mediate local chromatin modifications.

HDAC3 HDAC1

2.76e-053106218854353
Pubmed

HDAC1, HDAC4, and HDAC9 Bind to PC3/Tis21/Btg2 and Are Required for Its Inhibition of Cell Cycle Progression and Cyclin D1 Expression.

HDAC9 HDAC1

2.76e-053106227333946
Pubmed

Combination of polymorphisms within the HDAC1 and HDAC3 gene predict tumor recurrence in hepatocellular carcinoma patients that have undergone transplant therapy.

HDAC3 HDAC1

2.76e-053106220731616
Pubmed

Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.

HDAC3 HDAC1

2.76e-053106233637599
Pubmed

Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo.

HDAC3 HDAC1

2.76e-053106218347167
Pubmed

The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB.

HDAC3 HDAC1

2.76e-053106223087373
Pubmed

Nuclear Smad7 Overexpressed in Mesenchymal Cells Acts as a Transcriptional Corepressor by Interacting with HDAC-1 and E2F to Regulate Cell Cycle.

HDAC3 HDAC1

2.76e-053106223213415
Pubmed

Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells.

HDAC3 HDAC1

2.76e-053106220484017
Pubmed

Expression patterns of histone deacetylases in bovine oocytes and early embryos, and the effect of their inhibition on embryo development.

HDAC3 HDAC1

2.76e-053106211358320
Pubmed

Type-specific roles of histone deacetylase (HDAC) overexpression in ovarian carcinoma: HDAC1 enhances cell proliferation and HDAC3 stimulates cell migration with downregulation of E-cadherin.

HDAC3 HDAC1

2.76e-053106220049841
Pubmed

Retinoic acid and histone deacetylases regulate epigenetic changes in embryonic stem cells.

HDAC3 HDAC1

2.76e-053106224821725
Pubmed

Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos.

HDAC3 HDAC1

2.76e-053106218501342
Pubmed

The Metabolic Regulator Histone Deacetylase 9 Contributes to Glucose Homeostasis Abnormality Induced by Hepatitis C Virus Infection.

HDAC9 HDAC3

2.76e-053106226420860
Pubmed

Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3.

HDAC3 HDAC1

2.76e-053106218789002
Pubmed

Structural and biochemical mechanisms of NLRP1 inhibition by DPP9.

NLRP1 DPP8

2.76e-053106233731929
Pubmed

DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation.

NLRP1 DPP8

2.76e-053106233731932
Pubmed

HDAC inhibition activates the apoptosome via Apaf1 upregulation in hepatocellular carcinoma.

HDAC3 HDAC1

2.76e-053106227342975
Pubmed

Circulating Sestrin Levels Are Increased in Hypertension Patients.

SESN3 SESN1

2.76e-053106232626541
Pubmed

Interactions between microRNA-200 family and Sestrin proteins in endometrial cancer cell lines and their significance to anoikis.

SESN3 SESN1

2.76e-053106231073887
Pubmed

Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation.

HDAC3 HDAC1

2.76e-053106223475113
Pubmed

Phylogeny and structure of the RING3 gene.

NLRP1 BRD2

2.76e-05310628781126
Pubmed

Class I histone deacetylases 1, 2 and 3 are highly expressed in classical Hodgkin's lymphoma.

HDAC3 HDAC1

2.76e-053106220415600
Pubmed

Expression of histone deacetylases 1, 2 and 3 in histological subtypes of testicular germ cell tumours.

HDAC3 HDAC1

2.76e-053106221972094
Pubmed

Downregulation of Cell Cycle and Checkpoint Genes by Class I HDAC Inhibitors Limits Synergism with G2/M Checkpoint Inhibitor MK-1775 in Bladder Cancer Cells.

HDAC3 HDAC1

2.76e-053106233670166
Pubmed

PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene family in human and mouse.

SESN3 SESN1

2.76e-053106212607115
Pubmed

Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing.

HDAC3 HDAC1

2.76e-053106211006275
Pubmed

The functions and roles of sestrins in regulating human diseases.

SESN3 SESN1

2.76e-053106234979914
Pubmed

Histone deacetylase inhibitors downregulate checkpoint kinase 1 expression to induce cell death in non-small cell lung cancer cells.

HDAC3 HDAC1

2.76e-053106221179472
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRAS1 NRCAM SPEG ADCY2 TENM4 RAB3GAP2 TCF25 PCNT

3.65e-05407106812693553
Pubmed

LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and α-synuclein-induced degeneration in cellular models of Parkinson's disease.

HDAC9 HDAC3

5.50e-054106234119632
Pubmed

Insufficient p65 phosphorylation at S536 specifically contributes to the lack of NF-kappaB activation and transformation in resistant JB6 cells.

HDAC3 HDAC1

5.50e-054106215192014
Pubmed

Phosphorylation of RUNX1 by cyclin-dependent kinase reduces direct interaction with HDAC1 and HDAC3.

HDAC3 HDAC1

5.50e-054106221059642
Pubmed

Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family.

HDAC3 HDAC1

5.50e-05410629346952
Pubmed

Histone acetylation regulates prostate ductal morphogenesis through a bone morphogenetic protein-dependent mechanism.

HDAC3 HDAC1

5.50e-054106226283270
Pubmed

Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1.

HDAC3 HDAC1

5.50e-054106215917248
Pubmed

Histone deacetylases specifically down-regulate p53-dependent gene activation.

HDAC3 HDAC1

5.50e-054106210777477
Pubmed

HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury.

HDAC3 HDAC1

5.50e-054106233907245
Pubmed

A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.

CDC42BPA CDC42BPB

5.50e-054106218854160
Pubmed

Class I HDAC activity is required for renal protection and regeneration after acute kidney injury.

HDAC3 HDAC1

5.50e-054106224808536
Pubmed

Expression profile of class I histone deacetylases in human cancer tissues.

HDAC3 HDAC1

5.50e-054106217786334
Pubmed

Ovol1 represses its own transcription by competing with transcription activator c-Myb and by recruiting histone deacetylase activity.

HDAC3 HDAC1

5.50e-054106217311813
Pubmed

PI3Kδ and primary immunodeficiencies.

PIK3R3 PIK3R2

5.50e-054106227616589
Pubmed

Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome.

NLRP1 DPP8

5.50e-054106229396289
Pubmed

Cell signaling switches HOX-PBX complexes from repressors to activators of transcription mediated by histone deacetylases and histone acetyltransferases.

HDAC3 HDAC1

5.50e-054106211046157
Pubmed

The growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylases.

HDAC3 HDAC1

5.50e-054106211259576
Pubmed

Association of regions on chromosomes 6 and 7 with blood pressure in Nigerian families.

HDAC9 CPED1

5.50e-054106220031566
Pubmed

HDAC1/3-dependent moderate liquid-liquid phase separation of YY1 promotes METTL3 expression and AML cell proliferation.

HDAC3 HDAC1

5.50e-054106236424383
Pubmed

Histone deacetylase 3 binds to and regulates the multifunctional transcription factor TFII-I.

HDAC3 HDAC1

5.50e-054106212393887
Pubmed

Class I histone deacetylase activity is required for proliferation of renal epithelial cells.

HDAC3 HDAC1

5.50e-054106223698124
Pubmed

High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo.

HDAC3 HDAC1

5.50e-054106219912635
Pubmed

Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3.

SESN3 SESN1

5.50e-054106222958918
Pubmed

Regulation of adipogenesis by nuclear receptor PPARγ is modulated by the histone demethylase JMJD2C.

HDAC3 HDAC1

5.50e-054106221637537
Pubmed

Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization.

CDC42BPA CDC42BPB

5.50e-05410629418861
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEB2 POTEJ POTEB

1.12e-0513633685
GeneFamilyAnkyrin repeat domain containing

TRPA1 POTEB2 SHANK3 ANKRD44 ANKRD28 POTEJ POTEB

2.06e-05242637403
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

HDAC3 HDAC1

7.14e-054632989
GeneFamilyProtein phosphatase 6 regulatory subunits

ANKRD44 ANKRD28

1.78e-046632699
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

FLT4 NRCAM KALRN SPEG ADGRF5

2.44e-04161635593
GeneFamilyWD repeat domain containing|BEACH domain containing

WDR81 LYST

4.23e-0496321230
GeneFamilySH2 domain containing

PIK3R3 PIK3R2 SH2D7

5.27e-03101633741
CoexpressionGSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP

CDC42BPA WEE1 MARS1 PIK3R3 OCA2 DPP8 HDAC3 PIK3R2

9.60e-071871068M6807
CoexpressionFIRESTEIN_PROLIFERATION

RPS6KA4 KALRN SPEG STK32B PIK3R3 STK32A IKBKE

5.18e-061661067M5354
CoexpressionGSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_DN

PIK3R3 SESN3 COQ2 CPED1 SESN1 GCLC PRMT7

1.75e-052001067M8584
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 KALRN PIK3R3 RAPGEF4 NLRP1 PKHD1L1 SHANK3 ADGRF5

2.09e-081931068287e756d5fd3bd2931c168da24beaa0d02a350ae
ToppCellCOVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

HDAC9 KALRN PIK3R3 RAPGEF4 PKHD1L1 SHANK3 MET

3.30e-0718710672d20193a6cacdfa4877457c97b0077408942186c
ToppCellCOPD-Endothelial|COPD / Disease state, Lineage and Cell class

FLT4 KALRN PIK3R3 RAPGEF4 PKHD1L1 SHANK3 ADGRF5

4.08e-071931067093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCellControl-Endothelial|Control / Disease state, Lineage and Cell class

FLT4 KALRN PIK3R3 RAPGEF4 PKHD1L1 SHANK3 ADGRF5

4.23e-071941067485fe5538fabec457b9a51feb641f2a91cbf4e18
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 PKHD1L1 SHANK3 ADGRF5

4.53e-07196106722767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 PKHD1L1 SHANK3 ADGRF5

4.53e-071961067adee900dcd16dbaba15c58bdcace09ba20214950
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HDAC9 NRCAM KALRN SPEG CPED1 ADCY2 NELL2

4.53e-0719610679830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellnucseq-Endothelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FLT4 CDC42BPA KALRN PIK3R3 RAPGEF4 PKHD1L1 SHANK3

4.69e-071971067ebf9be068eaa658493fa7884fd19f34642922acb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 SHANK3 ADGRF5 POTEJ

2.02e-061561066f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 SIM2 PKHD1L1 ADCY2 HEPHL1 DNAH9

2.34e-061601066c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 SIM2 PKHD1L1 ADCY2 HEPHL1 DNAH9

2.34e-06160106625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE7A RAPGEF4 SESN3 SESN1 STK32A TENM4

2.80e-06165106622293c6b55f44636440cd737efb786ff5de3373d
ToppCellControl-Endothelial_cells-Systemic_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

FLT4 KALRN STK32B PIK3R3 RAPGEF4 SHANK3

3.56e-061721066c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TCTE1 KALRN PIK3R3 NLRP1 SHANK3 ADGRF5

3.80e-0617410663d4c05ea5719ca65e85d1f15198453034791087c
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

FLT4 KALRN STK32B RAPGEF4 PKHD1L1 SHANK3

4.06e-06176106698c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

FLT4 KALRN STK32B RAPGEF4 PKHD1L1 SHANK3

4.06e-061761066c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM STK32B SIM2 TENM4 SORCS2 GP2

4.33e-061781066dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM STK32B SIM2 STK32A TENM4 GP2

4.33e-0617810664df6218b20c2f076c22346d23260964cc0d73e65
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM STK32B SIM2 TENM4 SORCS2 GP2

4.47e-061791066d0fa700648db8ce76a8aa689879a25048299fa40
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM STK32B SIM2 TENM4 SORCS2 GP2

4.47e-0617910662e49b215b71438400aebb483f2c2c08d5e956961
ToppCellControl-Endothelial_cells-Pulmonary_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

HDAC9 KALRN PIK3R3 RAPGEF4 PKHD1L1 SHANK3

5.08e-06183106646be9f96755c7b65aeac061d95d15abeb6466034
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 NRCAM KALRN PKHD1L1 TENM4 DNAH9

5.24e-0618410662cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 NRCAM KALRN PKHD1L1 TENM4 DNAH9

5.24e-061841066ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 NRCAM KALRN PKHD1L1 TENM4 DNAH9

5.24e-0618410662b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM STK32B SIM2 TENM4 SORCS2 GP2

5.41e-06185106603f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCellILEUM-inflamed-(7)_Lymphatics|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FLT4 KALRN STK32B SHANK3 NELL2 ADGRF5

5.41e-061851066d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

5.75e-06187106635c382c0aabd46906113e5db30ea24bb8e658899
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

FLT4 KALRN STK32B RAPGEF4 PKHD1L1 SHANK3

5.75e-0618710661e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

FLT4 KALRN STK32B RAPGEF4 PKHD1L1 SHANK3

5.93e-06188106680910dcbb51990f2baed240f319456c0d3fa2065
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLT4 KALRN STK32B RAPGEF4 PKHD1L1 SHANK3

5.93e-061881066c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HDAC9 KALRN RAPGEF4 WDR81 SHANK3 TTC23

6.11e-061891066bccb3481ffed597c845fe860da658505316105b5
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

HDAC9 KALRN RAPGEF4 PKHD1L1 LYST SHANK3

6.30e-0619010661caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLT4 KALRN STK32B RAPGEF4 PKHD1L1 SHANK3

6.30e-0619010666e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

FLT4 KALRN STK32B RAPGEF4 PKHD1L1 SHANK3

6.30e-06190106691bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

6.49e-061911066f663131a4810584c5854bd64ee7991a237b7707f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

6.69e-06192106628eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

6.69e-061921066c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HDAC9 KALRN PIK3R3 RAPGEF4 PKHD1L1 SHANK3

6.89e-0619310669ba688b35a9ead5d04691b3f3f15484f02dbbd0d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 RAPGEF4 NLRP1 PKHD1L1 SHANK3 ADGRF5

6.89e-061931066456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

6.89e-06193106652e918884877b6659cdca0496390e440f73694a9
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FRAS1 PKHD1L1 CHRD DNAH9 ALOX12B

6.94e-0611110651847dde68d349114286bc3317be6339666df4aa2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 PKHD1L1 SHANK3

7.09e-061941066cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.09e-061941066f76808666fb875fc787751cbfd924d9be20a8192
ToppCellIPF-Endothelial|IPF / Disease state, Lineage and Cell class

KALRN PIK3R3 RAPGEF4 PKHD1L1 SHANK3 ADGRF5

7.09e-0619410669591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.09e-061941066f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.09e-061941066e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.09e-061941066a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.52e-0619610668ad8efb631164b46f0c082572270188e5ead20bf
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

HDAC9 DPY19L1 SIM2 MET TENM4 GP2

7.52e-06196106604f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AOC1 NRCAM APLP1 CELSR3 POTEJ GP2

7.52e-06196106695544097577f20ed7f4144bd940471cde0617554
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.52e-061961066ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.52e-061961066b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellnucseq-Endothelial-Endothelial_Vascular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CDC42BPA KALRN PIK3R3 RAPGEF4 SHANK3 ADGRF5

7.52e-061961066686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.52e-0619610669606ea7e42f707e69ea891b3521037613b9675f5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.52e-061961066145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.52e-061961066b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

FLT4 CDC42BPA KALRN RAPGEF4 SHANK3 ADGRF5

7.52e-0619610664ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.52e-061961066d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FRAS1 SESN3 ANKRD44 LNPEP TCF25 ZNF292

7.74e-06197106657ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.74e-061971066cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.74e-0619710660f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HDAC9 KALRN RAPGEF4 PKHD1L1 LYST SHANK3

7.74e-061971066b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.74e-061971066412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.97e-06198106607701c73137947ed4a27e225975329235bbb8734
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.97e-06198106631ba87552be97c9b78c9e82f98e96699ccb19824
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.97e-0619810661378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.97e-061981066451003a21162eeae90739fdb502bb50b362d80c8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.97e-061981066953630dbe3154b1b102b87de0feca2cbf124eabe
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLT4 KALRN STK32B RAPGEF4 PKHD1L1 SHANK3

7.97e-0619810669ab0db78394e730f6866b2db80047149024ad5f6
ToppCellTracheal-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLT4 KALRN RAPGEF4 PKHD1L1 SHANK3 ADGRF5

7.97e-06198106677e31b6edeeb5ccd5cd3f080898c96bf9ab9f98d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.97e-061981066440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.97e-061981066fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.97e-0619810660a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN RAPGEF4 NLRP1 SHANK3 ADGRF5

7.97e-0619810668e45551224fbb30c0658ad47dd98335ecf165437
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLT4 KALRN STK32B RAPGEF4 PKHD1L1 SHANK3

7.97e-061981066e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellCOVID-19-kidney-Glomerular_EC|kidney / Disease (COVID-19 only), tissue and cell type

FLT4 RAPGEF4 NLRP1 PKHD1L1 SHANK3 ADGRF5

8.20e-061991066fffd2f9042b55531dac4e5b463b5cee80402e7bb
ToppCellParenchymal-10x5prime-Endothelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FLT4 PIK3R3 RAPGEF4 PKHD1L1 SHANK3 ADGRF5

8.44e-0620010660e648e9eb96c83a94505d07323785a7a40997eb0
ToppCellBronchial-10x5prime-Endothelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FLT4 PIK3R3 RAPGEF4 PKHD1L1 SHANK3 ADGRF5

8.44e-062001066ad34c978cc6b89b4c1c8c9b2fb2a938051b555a0
ToppCellAT2_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

CDC42BPG FRAS1 NRCAM STK32B PIK3R2

1.55e-051311065ff4e618bd944f852bbd34438f740187aca82460f
ToppCellCOVID-19-kidney-Mito-rich_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLT4 KALRN RAPGEF4 SHANK3 ADGRF5

2.53e-051451065afed661aef990edb8e7012ab67ace56443520c9f
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

PDE7A CRY1 ANKRD44 NELL2 ZC3HAV1

3.59e-0515610651545169694f686d28648a68b552c2ae606599d66
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCTE1 CDC42BPG STK32A TNNI3K CFAP46

3.70e-051571065741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

FLT4 KALRN RAPGEF4 SHANK3 ADGRF5

4.05e-0516010650d4880f85565d8c540c94a8f8109147b3029279a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCTE1 CDC42BPG STK32B ANKRD44 TNNI3K

4.05e-0516010650bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM STK32B SIM2 TENM4 GP2

4.05e-05160106503b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SPEG SESN3 ANKRD44 NELL2 LNPEP

4.30e-051621065b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RAPGEF4 NLRP1 SHANK3 ADGRF5 DCAF4L1

4.83e-051661065ec719368295133da2f7ff587c5329ed6db1dd56d
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRAS1 KALRN GCLC CHRD ANKRD28

4.83e-051661065bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRAS1 KALRN GCLC CHRD ANKRD28

4.83e-0516610655e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

FLT4 KALRN STK32B PKHD1L1 SHANK3

4.83e-051661065c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 MEP1A ADGRF5 SH2D7 GP2

4.97e-0516710657cb5b52aaa5b595fe2e97d9e175294ea8d63b165
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 RAPGEF4 PKHD1L1 SHANK3 ADGRF5

5.26e-051691065987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG SHANK3 ADGRF5 HEPHL1 SH2D7

5.26e-051691065c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell(7)_MNP-(7)_DC_activated|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

AOC1 NRCAM RGS11 NELL2 PRAME

5.41e-0517010654ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_mature_DC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

AOC1 NRCAM NELL2 POTEJ PRAME

5.56e-051711065341f9f79c1ed654ab347e25dc4936f89ffdf9617
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APLP1 IKBKE ANKRD28 ELF4 ZC3HAV1

5.71e-05172106510a1d1838492b8ce6dea08844353b51571432c56
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NRCAM STK32B SIM2 SORCS2 GP2

5.71e-0517210651565f38266891c3acf49778838de134c5dee5460
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APLP1 IKBKE ANKRD28 ELF4 ZC3HAV1

5.71e-051721065d824e46c8040b0bb9235f9b8a2b35386b303caa0
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

FLT4 KALRN STK32B PKHD1L1 SHANK3

5.87e-051731065dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCelldroplet-Heart-HEART-1m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 NRCAM WDR81 PKHD1L1 MET

5.87e-0517310659dc7746a84f0e268a7c061e1bbcd5e31903034dc
DrugNSC3852

HDAC9 NLRP1 HDAC3 HDAC1

1.88e-06201044CID000019103
Drugpholedrine sulfuric acid ester

AOC1 LYST BRD2

7.62e-0691043CID003082701
DrugCI-994

HDAC9 HDAC3 HDAC1

1.09e-05101043CID000002746
DrugAlexidine dihydrochloride [22573-93-9]; Up 200; 6.8uM; HL60; HT_HG-U133A

HDAC9 ZNF573 CDC42BPA SZT2 MARS1 NLRP1 CRY1

2.05e-0518210472576_UP
Drug7-tricosene

TRRAP LYST

2.07e-0521042CID006365493
DrugPimelic Acids

HDAC3 HDAC1

2.07e-0521042ctd:D010867
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPG CDC42BPA CDC42BPB

6.68e-06111033DOID:0060669 (implicated_via_orthology)
Diseaseazoospermia (implicated_via_orthology)

CDC42BPG CDC42BPA CDC42BPB

1.14e-04271033DOID:14227 (implicated_via_orthology)
Diseaseglucagon-like peptide-1 measurement, glucose tolerance test

UNCX RAPGEF4

3.33e-0481032EFO_0004307, EFO_0008465
DiseaseAdenocarcinoma of large intestine

TRRAP CDC42BPB MET TNNI3K

3.64e-04961034C1319315
DiseaseSpastic Paraplegia

LYST RAB3GAP2

4.28e-0491032C0037772
Diseaselifestyle measurement, systolic blood pressure

KALRN DAPK2

4.28e-0491032EFO_0006335, EFO_0010724
DiseaseGastric Adenocarcinoma

SPEG TRRAP BRD2

5.27e-04451033C0278701
DiseaseGlioblastoma Multiforme

CDC42BPG MET BRD2 STKLD1

6.30e-041111034C1621958
DiseaseSquamous cell carcinoma of the head and neck

WEE1 MET TNNI3K

8.06e-04521033C1168401
DiseaseMetastatic melanoma

FLT4 STK32B STK32A

9.00e-04541033C0278883
Diseaseuric acid measurement

CDC42BPG FRAS1 FLT4 RPS6KA4 CDC42BPA UNCX STK32B ANKRD28

1.36e-036101038EFO_0004761
Diseaseserum gamma-glutamyl transferase measurement

CDC42BPA KALRN PIK3R3 NLRP1 CDC42BPB MET TENM4 GCLC STKLD1 ZNF292

1.36e-0391410310EFO_0004532
Diseaseretinopathy

HDAC9 TENM4

1.59e-03171032EFO_0003839
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

FLT4 MET PRAME ALOX12B

1.83e-031481034C0279702
DiseaseAutistic Disorder

NRCAM TRRAP SHANK3 MET ZNF292

2.26e-032611035C0004352
DiseaseSarcoma

FLT4 PRAME

2.43e-03211032C1261473
DiseaseInfiltrating duct carcinoma of female breast

RPS6KA4 CDC42BPB

2.43e-03211032C3165106
Diseasesmoking status measurement

RPS6KA4 CDC42BPA PDE7A STK32B CDC42BPB ADCY2 MET TNNI3K TENM4 LNPEP RAB3GAP2

2.43e-03116010311EFO_0006527
DiseaseManic

ADCY2 SHANK3 TENM4

2.60e-03781033C0338831
Diseaseprostate carcinoma (is_marker_for)

MET HDAC3

2.91e-03231032DOID:10286 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
FHTLVYHILATVDGH

ADPGK

381

Q9BRR6
YLHHTINLTHSLLAA

nan

41

Q9N2K0
ELQLHQHILTQHGYT

CPED1

111

A4D0V7
HTLRHYQHVAAVDPE

APLP1

426

P51693
LAAYHGHHQALEVLV

ANKRD28

556

O15084
VVYVLNHNHHLILAG

CFAP46

741

Q8IYW2
EDLETVIHHVHSLYP

ABHD3

196

Q8WU67
IGNIHTHLVHYRVDL

AOC1

506

P19801
AQYSHHVIQEILGHL

EFR3A

286

Q14156
QDVVVLDHAYHGHLS

PHYKPL

131

Q8IUZ5
LDHAYHGHLSSLIDI

PHYKPL

136

Q8IUZ5
IYHDESLGAHINVVL

ADAMTS2

301

O95450
HLEVLDIHHTDQGCY

CFAP251

781

Q8TBY9
AHLHLIEYVGEQTAL

OCA2

696

Q04671
FHHLLHITVLNSYIL

PGBD4

456

Q96DM1
EALHLGAVLVQHGYI

RGS11

71

O94810
LAIHSLHQLGYVHRD

CDC42BPG

181

Q6DT37
EYAVSSHHHVICELL

POTEB2

306

H3BUK9
YGVDHLGEEAILQVH

RAB3GAP2

1281

Q9H2M9
GAHLTHQIYTLDIHR

COQ2

311

Q96H96
DHYQLGDLVAGLSHL

TCTE1

226

Q5JU00
LHNLHFLLSESIYRH

FRAS1

3356

Q86XX4
GVILSIHHLDHRYLE

NELL2

101

Q99435
ALHEDIYVLHENGTL

NRCAM

496

Q92823
YHQRVLYIDIDIHHG

HDAC1

166

Q13547
LHLYSGLELDDVHNG

ELF4

46

Q99607
VHVFSLSQAVLHHIY

IKBKE

311

Q14164
HVNESAYLPLHVHEE

DCAF4L1

311

Q3SXM0
HLFSLHGLIEYFHLD

PDE7A

176

Q13946
LLYHRVHPEEVTFHL

NLRP1

1236

Q9C000
AGHYDLVFLHCEIHL

GP2

451

P55259
EGIDHLLAQHVAHLF

GCLC

361

P48506
ELAIHHHQTLYEQVT

KALRN

451

O60229
FDHGELVYHALQLLA

DPY19L1

446

Q2PZI1
DVFQHAVVLYLHNHS

LNPEP

566

Q9UIQ6
ANDYLVTSHIHLHVP

LONP1

831

P36776
VVNLHEVHHDQLHTY

RPS6KA4

466

O75676
EVHHDQLHTYLVLEL

RPS6KA4

471

O75676
LHLAAYNGHHQALEV

ANKRD44

571

Q8N8A2
LAIDSIHQLHYVHRD

CDC42BPB

186

Q9Y5S2
VIDHHNYDISDLGQH

DDOST

156

P39656
SQDPEHSLTEYIHHL

PCNT

3296

O95613
HSLTEYIHHLEVIQQ

PCNT

3301

O95613
HPRVLYIDIDIHHGD

HDAC3

161

O15379
ELVLHYQHASLVQHN

PIK3R2

691

O00459
NSVVELINHYHHESL

PIK3R3

131

Q92569
VGYNTILLHTHAHVL

ADCY2

771

Q08462
ILLHTHAHVLGDYSQ

ADCY2

776

Q08462
LPSYEHAHRHLVEEN

PRMT7

156

Q9NVM4
VLHHNVITLHDVYEN

DAPK2

81

Q9UIK4
RDDHELHIHPASVLY

DHX35

631

Q9H5Z1
ESGEHYELHLLHYLQ

DPP8

871

Q6V1X1
ILHYAHGDSQQTHLL

CRY1

536

Q16526
LVLYLSELIHNHQGE

LYST

2791

Q99698
YSHEAIAHLLETHLI

ALOX12B

391

O75342
IGSEVDIHTIHYHAE

HEPHL1

996

Q6MZM0
ILDFYIHESVQRHGH

ATAT1

121

Q5SQI0
VYAVALIDSEHHVGH

FAM172BP

256

A6NC97
HEFLLVHHLQRANYV

AHCTF1

951

Q8WYP5
AHLLQLQLHHYEDEV

DNAH9

1406

Q9NYC9
QLVHSEHHSLLYGTN

HDAC9

691

Q9UKV0
RALHDHCYVHINITD

CELSR3

836

Q9NYQ7
NIAYEHILSHLHEVR

CA14

171

Q9ULX7
EHLLQVHIASYLGEH

GARIN1A

291

Q6NXP2
ILHEHHIFLGATNYI

MET

56

P08581
EGHVATHFHLIAQEL

RTL3

336

Q8N8U3
SYDFHLRLVHQHVLG

SZT2

3046

Q5T011
VHELELIYHTFGRHN

RAPGEF4

791

Q8WZA2
THHQVYGQATELAEH

TEX55

306

Q96M34
LVGNHVNHLIHLIYD

TRNT1

246

Q96Q11
LAELVHAVVLLTHYH

SESN1

196

Q9Y6P5
IHGTLHLERLAYLHA

PRAME

451

P78395
EYAVSSHHHVICELL

POTEB

306

A0A0A6YYL3
AIIEHEILHALGFYH

MEP1A

151

Q16819
EHHILYLDHGGVIVA

SORCS2

561

Q96PQ0
EYAVSSHHHVICQLL

POTEJ

306

P0CG39
LHHHLLQEYEIERSF

SIM2

146

Q14190
NILLDEHGHVHITDF

STK32A

151

Q8WU08
VIAIDSVHQLHYVHR

CDC42BPA

186

Q5VT25
VDASALGLHDYHDII

BRD2

376

P25440
NYESTIHPLSLHEHE

ADGRF5

26

Q8IZF2
THCHLHYEVLLAGLG

CHRD

561

Q9H2X0
VDLHFIALVHVDGHL

UCHL3

166

P15374
EVYAHAVLGQHSHVV

WEE1

346

P30291
HHELADYLISVGADI

TRPA1

321

O75762
AFIYASHIVQHERIH

ZNF573

226

Q86YE8
FIEIHHHLGSVILIF

STYXL1

231

Q9Y6J8
RQVLEGIHYLHQSHV

SPEG

1701

Q15772
GIHYLHQSHVLHLDV

SPEG

1706

Q15772
GHVQHLEHLLFYGAD

SHANK3

261

Q9BYB0
ISNHLYTPEHHLIQA

TTI2

296

Q6NXR4
VLDALEYLHHLDIIH

STKLD1

141

Q8NE28
VHAVVLLAHYHALAS

SESN3

191

P58005
LLLHEVHANDTGSYV

FLT4

96

P35916
YHGDSHLQLERINVH

TUBB8B

36

A6NNZ2
LNYVVHLEADHGIGL

ZNF292

2231

O60281
AILNHAHYLENLHFT

TENM4

2596

Q6N022
HSTLAELVHHYQEAQ

SH2D7

116

A6NKC9
HNTHHLLVERNIIYD

PKHD1L1

2506

Q86WI1
HSLLHAHSEQLQALY

TXNDC11

876

Q6PKC3
LESAALIHHYVIHTG

ZNF264

381

O43296
NRAHLIQHYIIHTGE

ZNF550

326

Q7Z398
NILLDEHGHVHITDF

STK32B

151

Q9NY57
LGLHDVSINHFLQAH

TTC23

241

Q5W5X9
SEIHHLHPEYVRVSE

ZC3HAV1

731

Q7Z2W4
SHNILLYEDGHAVVA

TNNI3K

591

Q59H18
DLLYHLHGGDSHSVL

ZFYVE26

431

Q68DK2
YSTLADLVHHVRQHL

TRRAP

376

Q9Y4A5
LLAHVTLELQHYHQL

MARS1

681

P56192
HVLYVEHRHLNPDTE

TCF25

176

Q9BQ70
LHLVDAHTHLASYGV

WDR81

566

Q562E7
HHVYELAGHQLQSAA

UNCX

31

A6NJT0
LEHPSVSRYHAVLQH

SLC4A1AP

201

Q9BWU0