Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	KIF3B KIF27 NAV1 MACF1 TOMM20 CHD3 CHD6 KIF17 DHX8 HELLS	3.59e-05	614	67	10	GO:0140657
GeneOntologyMolecularFunction	histone H3K36 trimethyltransferase activity	NSD2 ASH1L	1.10e-04	5	67	2	GO:0140955
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF3B KIF27 NAV1 MACF1 CHD3 CHD6 KIF17 DHX8	1.11e-04	441	67	8	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD3 CHD6 HELLS	2.59e-04	37	67	3	GO:0140658
GeneOntologyMolecularFunction	chromatin binding	AKAP8 NSD2 ASH1L CHD3 CHD6 ATF4 NFAT5 ZFX HELLS	7.77e-04	739	67	9	GO:0003682
GeneOntologyMolecularFunction	histone H3K36 methyltransferase activity	NSD2 ASH1L	8.45e-04	13	67	2	GO:0046975
GeneOntologyCellularComponent	chromatin	AKAP8 HOXD12 SLF2 NSD2 TET1 RNF40 CHD3 CHD6 ATF4 EMX1 NFAT5 ZFX PROX1 HELLS	1.77e-04	1480	66	14	GO:0000785
GeneOntologyCellularComponent	catalytic step 2 spliceosome	CWC27 GPATCH1 PRPF6 DHX8	2.52e-04	97	66	4	GO:0071013
Domain	Zinc_finger_PHD-type_CS	NSD2 ASH1L CHD3 SP140	8.69e-05	65	67	4	IPR019786
Domain	ATG_C	VPS13C ATG2B	1.26e-04	5	67	2	PF09333
Domain	AWS	NSD2 ASH1L	1.26e-04	5	67	2	SM00570
Domain	AWS	NSD2 ASH1L	1.26e-04	5	67	2	PS51215
Domain	AWS_dom	NSD2 ASH1L	1.26e-04	5	67	2	IPR006560
Domain	Autophagy-rel_C	VPS13C ATG2B	1.26e-04	5	67	2	IPR015412
Domain	PHD	NSD2 ASH1L CHD3 SP140	1.52e-04	75	67	4	PF00628
Domain	Znf_PHD-finger	NSD2 ASH1L CHD3 SP140	1.86e-04	79	67	4	IPR019787
Domain	SNF2_N	CHD3 CHD6 HELLS	2.03e-04	32	67	3	IPR000330
Domain	SNF2_N	CHD3 CHD6 HELLS	2.03e-04	32	67	3	PF00176
Domain	FERM_N	PTPN13 RDX TLN2	2.23e-04	33	67	3	PF09379
Domain	FERM_N	PTPN13 RDX TLN2	2.23e-04	33	67	3	IPR018979
Domain	DNA/RNA_helicase_DEAH_CS	CHD3 CHD6 DHX8	2.66e-04	35	67	3	IPR002464
Domain	PHD	NSD2 ASH1L CHD3 SP140	2.94e-04	89	67	4	SM00249
Domain	Znf_PHD	NSD2 ASH1L CHD3 SP140	3.20e-04	91	67	4	IPR001965
Domain	DEAH_ATP_HELICASE	CHD3 CHD6 DHX8	3.40e-04	38	67	3	PS00690
Domain	VPS13_N	VPS13C ATG2B	3.50e-04	8	67	2	IPR026854
Domain	Chorein_N	VPS13C ATG2B	3.50e-04	8	67	2	PF12624
Domain	ZF_PHD_2	NSD2 ASH1L CHD3 SP140	3.77e-04	95	67	4	PS50016
Domain	ZF_PHD_1	NSD2 ASH1L CHD3 SP140	3.92e-04	96	67	4	PS01359
Domain	Kinesin_motor_CS	KIF3B KIF27 KIF17	4.27e-04	41	67	3	IPR019821
Domain	Kinesin-like_fam	KIF3B KIF27 KIF17	4.91e-04	43	67	3	IPR027640
Domain	KINESIN_MOTOR_1	KIF3B KIF27 KIF17	5.26e-04	44	67	3	PS00411
Domain	-	KIF3B KIF27 KIF17	5.26e-04	44	67	3	3.40.850.10
Domain	Kinesin_motor_dom	KIF3B KIF27 KIF17	5.26e-04	44	67	3	IPR001752
Domain	Kinesin	KIF3B KIF27 KIF17	5.26e-04	44	67	3	PF00225
Domain	KINESIN_MOTOR_2	KIF3B KIF27 KIF17	5.26e-04	44	67	3	PS50067
Domain	KISc	KIF3B KIF27 KIF17	5.26e-04	44	67	3	SM00129
Domain	Helicase_C	CHD3 CHD6 DHX8 HELLS	5.91e-04	107	67	4	PF00271
Domain	HELICc	CHD3 CHD6 DHX8 HELLS	5.91e-04	107	67	4	SM00490
Domain	FERM_M	PTPN13 RDX TLN2	6.00e-04	46	67	3	PF00373
Domain	Helicase_C	CHD3 CHD6 DHX8 HELLS	6.12e-04	108	67	4	IPR001650
Domain	HELICASE_CTER	CHD3 CHD6 DHX8 HELLS	6.34e-04	109	67	4	PS51194
Domain	HELICASE_ATP_BIND_1	CHD3 CHD6 DHX8 HELLS	6.34e-04	109	67	4	PS51192
Domain	DEXDc	CHD3 CHD6 DHX8 HELLS	6.34e-04	109	67	4	SM00487
Domain	Helicase_ATP-bd	CHD3 CHD6 DHX8 HELLS	6.56e-04	110	67	4	IPR014001
Domain	-	PTPN13 RDX TLN2	7.22e-04	49	67	3	1.20.80.10
Domain	FERM_central	PTPN13 RDX TLN2	7.22e-04	49	67	3	IPR019748
Domain	FERM_domain	PTPN13 RDX TLN2	7.22e-04	49	67	3	IPR000299
Domain	FERM_1	PTPN13 RDX TLN2	7.67e-04	50	67	3	PS00660
Domain	FERM_2	PTPN13 RDX TLN2	7.67e-04	50	67	3	PS00661
Domain	FERM_3	PTPN13 RDX TLN2	7.67e-04	50	67	3	PS50057
Domain	Band_41_domain	PTPN13 RDX TLN2	7.67e-04	50	67	3	IPR019749
Domain	B41	PTPN13 RDX TLN2	7.67e-04	50	67	3	SM00295
Domain	FERM/acyl-CoA-bd_prot_3-hlx	PTPN13 RDX TLN2	7.67e-04	50	67	3	IPR014352
Domain	Post-SET_dom	NSD2 ASH1L	1.47e-03	16	67	2	IPR003616
Domain	PostSET	NSD2 ASH1L	1.47e-03	16	67	2	SM00508
Domain	POST_SET	NSD2 ASH1L	1.47e-03	16	67	2	PS50868
Domain	HMG_box_dom	NSD2 CHD3 PROX1	1.64e-03	65	67	3	IPR009071
Domain	Znf_FYVE_PHD	NSD2 ASH1L CHD3 SP140	1.92e-03	147	67	4	IPR011011
Domain	Actinin_actin-bd_CS	SYNE1 MACF1	3.06e-03	23	67	2	IPR001589
Domain	Spectrin	SYNE1 MACF1	3.06e-03	23	67	2	PF00435
Domain	ACTININ_2	SYNE1 MACF1	3.06e-03	23	67	2	PS00020
Domain	ACTININ_1	SYNE1 MACF1	3.06e-03	23	67	2	PS00019
Domain	Chromo_domain	CHD3 CHD6	3.33e-03	24	67	2	IPR023780
Domain	FERM_CS	RDX TLN2	3.33e-03	24	67	2	IPR019747
Domain	FERM_C	PTPN13 RDX	3.90e-03	26	67	2	PF09380
Domain	Chromo	CHD3 CHD6	3.90e-03	26	67	2	PF00385
Domain	FERM_C	PTPN13 RDX	4.20e-03	27	67	2	SM01196
Domain	FERM_PH-like_C	PTPN13 RDX	4.20e-03	27	67	2	IPR018980
Domain	CHROMO_1	CHD3 CHD6	4.51e-03	28	67	2	PS00598
Domain	CHROMO_2	CHD3 CHD6	4.51e-03	28	67	2	PS50013
Domain	Spectrin_repeat	SYNE1 MACF1	4.84e-03	29	67	2	IPR002017
Domain	Spectrin/alpha-actinin	SYNE1 MACF1	5.87e-03	32	67	2	IPR018159
Domain	Chromodomain-like	CHD3 CHD6	5.87e-03	32	67	2	IPR016197
Domain	SPEC	SYNE1 MACF1	5.87e-03	32	67	2	SM00150
Domain	Chromo/shadow_dom	CHD3 CHD6	6.23e-03	33	67	2	IPR000953
Domain	VG_K_chnl	KCNMA1 KCNQ3	6.23e-03	33	67	2	IPR028325
Domain	CHROMO	CHD3 CHD6	6.23e-03	33	67	2	SM00298
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP34 LIMK2 TCHH AKAP8 SH3TC1 NSD2 ASH1L MACF1 CHD3 FMNL2 CDKAL1 SENP7 PROX1 SP140	2.77e-08	1116	68	14	31753913
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIF3B SYNE1 NAV1 MACF1 CHD6 NFAT5 KIF17 CLEC16A SENP7	1.01e-07	407	68	9	12693553
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	USP34 PTPN13 TET1 ATG2B NAV1 RNF40 CHD3 CHD6 PROX1	1.27e-07	418	68	9	34709266
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	NEK4 USP34 PTPN1 AKAP8 VPS13C TUT7 NAV1 RNF40 CHD6 CDKAL1 DHX8	1.74e-07	733	68	11	34672954
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	AKAP8 SLF2 NSD2 GPATCH1 RNF40 CHD3 PRPF6 CHD6 RPL35 CDKAL1 ZFX DHX8 HELLS	1.15e-06	1294	68	13	30804502
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TLK2 KIF3B AKAP8 SYNE1 KCNMA1 NAV1 RDX MACF1 TLN2 GRIN2B PROX1	2.51e-06	963	68	11	28671696
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	USP34 PTPN1 PTPN13 AKAP8 VPS13C GPATCH1 RPL35 FMNL2 CLEC16A HELLS	2.64e-06	777	68	10	35844135
Pubmed	Prenatal stress disturbs hippocampal KIF17 and NR2B in spatial cognition in male offspring.	GRIN2B KIF17	3.77e-06	2	68	2	23239421
Pubmed	Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning.	PTPN1 EMX1	3.77e-06	2	68	2	22844492
Pubmed	Molecular motor KIF17 is fundamental for memory and learning via differential support of synaptic NR2A/2B levels.	GRIN2B KIF17	3.77e-06	2	68	2	21521616
Pubmed	CHD6 is a DNA-dependent ATPase and localizes at nuclear sites of mRNA synthesis.	CHD3 CHD6	3.77e-06	2	68	2	17027977
Pubmed	Mouse LIM-kinase 2 gene: cDNA cloning, genomic organization, and tissue-specific expression of two alternatively initiated transcripts.	LIMK2 KCNMA1	3.77e-06	2	68	2	9441759
Pubmed	The inhibitor of calcium/calmodulin-dependent protein kinase II KN93 attenuates bone cancer pain via inhibition of KIF17/NR2B trafficking in mice.	GRIN2B KIF17	3.77e-06	2	68	2	24836181
Pubmed	KIF17 Modulates Epileptic Seizures and Membrane Expression of the NMDA Receptor Subunit NR2B.	GRIN2B KIF17	3.77e-06	2	68	2	35678994
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	SYNE1 NAV1 MACF1 RNF40 ATF4	3.94e-06	120	68	5	31413325
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PTPN13 SH3TC1 NSD2 VPS13C OSBPL5 ASH1L KCNMA1 NAV1 MACF1 CHD3 CHD6 NFAT5 CLEC16A	5.37e-06	1489	68	13	28611215
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	USP34 SYNE1 MACF1 TLN2 CHD6 CLEC16A	5.37e-06	225	68	6	12168954
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP34 PTPN13 SLF2 SYNE1 ASH1L RDX MACF1 TLN2 RNF40 CHD6 GRIN2B FMNL2	6.61e-06	1285	68	12	35914814
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 TRMT6 NSD2 VPS13C TET1 OSBPL5 TOMM20 RNF40	9.02e-06	529	68	8	14621295
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	PTPN1 PTPN13 NSD2 ASH1L CHD3 ZFX PROX1 HELLS	9.53e-06	533	68	8	30554943
Pubmed	KIF17 dynamics and regulation of NR2B trafficking in hippocampal neurons.	GRIN2B KIF17	1.13e-05	3	68	2	12514209
Pubmed	Human gastric cancer progression and stabilization of ATG2B through RNF5 binding facilitated by autophagy-associated CircDHX8.	ATG2B DHX8	1.13e-05	3	68	2	38866787
Pubmed	Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load.	KIF3B KIF17	1.13e-05	3	68	2	28761002
Pubmed	The kinesin superfamily protein KIF17 is regulated by the same transcription factor (NRF-1) as its cargo NR2B in neurons.	GRIN2B KIF17	1.13e-05	3	68	2	21172391
Pubmed	Overexpression of forebrain PTP1B leads to synaptic and cognitive impairments in obesity.	PTPN1 EMX1	1.13e-05	3	68	2	38336024
Pubmed	Conditional deletions of epilepsy-associated KCNQ2 and KCNQ3 channels from cerebral cortex cause differential effects on neuronal excitability.	KCNQ3 EMX1	1.13e-05	3	68	2	24719109
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	AKAP8 KIF27 MACF1 TLN2 CHD3 PRPF6 DHX8 HELLS	1.79e-05	582	68	8	20467437
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PTPN1 TRMT6 KIF27 NSD2 VPS13C SYNE1 RDX TLN2 PRPF6 RPL35 DHX8 HELLS	1.86e-05	1425	68	12	30948266
Pubmed	Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.	CWC27 GPATCH1 PRPF6 DHX8	1.89e-05	80	68	4	11991638
Pubmed	Functional proteomics mapping of a human signaling pathway.	LIMK2 KIF3B ASH1L FAM161B MACF1 CHD3 CHD6 FMNL2	2.00e-05	591	68	8	15231748
Pubmed	ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization.	GRIN2B KIF17	2.25e-05	4	68	2	26085624
Pubmed	ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder.	ASH1L EMX1	2.25e-05	4	68	2	35081333
Pubmed	Ciliary targeting of olfactory CNG channels requires the CNGB1b subunit and the kinesin-2 motor protein, KIF17.	KIF3B KIF17	2.25e-05	4	68	2	16782012
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	TRMT6 CWC27 NSD2 CHD3 CHD6 SENP7 DHX8 HELLS	2.45e-05	608	68	8	36089195
Pubmed	Systematic perturbations of SETD2, NSD1, NSD2, NSD3, and ASH1L reveal their distinct contributions to H3K36 methylation.	NSD2 ASH1L	3.75e-05	5	68	2	39390582
Pubmed	Different roles for KIF17 and kinesin II in photoreceptor development and maintenance.	KIF3B KIF17	3.75e-05	5	68	2	19384852
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	KCNMA1 RDX TLN2 RNF40 CHD6 NFAT5 ZFX	4.01e-05	475	68	7	31040226
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	POLR1D PTPN13 AKAP8 NSD2 SYNE1 MACF1 PRPF6 CHD6 DHX8 PROX1	4.61e-05	1082	68	10	38697112
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	PTPN1 GPATCH1 RDX MACF1 TOMM20 PRPF6 RPL35	4.75e-05	488	68	7	31324722
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SYNE1 TUT7 TET1 SENP7	4.92e-05	102	68	4	11214970
Pubmed	NMDA receptors control development of somatosensory callosal axonal projections.	GRIN2B EMX1	5.62e-05	6	68	2	33661095
Pubmed	Histone H2A ubiquitination inhibits the enzymatic activity of H3 lysine 36 methyltransferases.	NSD2 ASH1L	5.62e-05	6	68	2	24019522
Pubmed	The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair.	CHD3 SENP7	5.62e-05	6	68	2	24018422
Pubmed	Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.	TLN2 GRIN2B	5.62e-05	6	68	2	20197096
Pubmed	Deletion of KCNQ2/3 potassium channels from PV+ interneurons leads to homeostatic potentiation of excitatory transmission.	KCNQ3 EMX1	5.62e-05	6	68	2	30382937
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	STX8 PTPN1 PTPN13 VPS13C ATG2B TOMM20 CDKAL1	5.82e-05	504	68	7	34432599
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	NSD2 NAV1 CHD6 ZFX	6.37e-05	109	68	4	33554859
Pubmed	Dmrt5, a Novel Neurogenic Factor, Reciprocally Regulates Lhx2 to Control the Neuron-Glia Cell-Fate Switch in the Developing Hippocampus.	EMX1 PROX1	7.86e-05	7	68	2	29025924
Pubmed	Regulation of cilium length and intraflagellar transport by the RCK-kinases ICK and MOK in renal epithelial cells.	KIF3B KIF17	7.86e-05	7	68	2	25243405
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	STX8 CNNM1 TRMT6 PTPN13 VPS13C SYNE1 NAV1 MACF1	7.95e-05	719	68	8	35337019
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	TLK2 POLR1D PTPN13 AKAP8 CWC27 MACF1 DHX8 HELLS	8.35e-05	724	68	8	36232890
Pubmed	Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex.	KCNQ3 GRIN2B EMX1	1.02e-04	46	68	3	35864088
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CLRN3 CWC27 NSD2 SYNE1 ASH1L RDX MACF1 TOMM20 CHD3 PRPF6 CHD6	1.05e-04	1442	68	11	35575683
Pubmed	Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis.	EMX1 PROX1	1.05e-04	8	68	2	21436036
Pubmed	Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon.	GRIN2B EMX1	1.05e-04	8	68	2	32710818
Pubmed	Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner.	NAPEPLD EMX1 QRSL1	1.09e-04	47	68	3	31097699
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	EXOC6 AKAP8 NSD2 TUT7 MACF1 CHD3 PRPF6 DHX8	1.16e-04	759	68	8	35915203
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	USP34 VPS13C KCNMA1 MACF1	1.19e-04	128	68	4	30995482
Pubmed	NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.	LIMK2 RNF40 PRPF6 DHX8	1.22e-04	129	68	4	23022380
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	AKAP8 GPATCH1 DHX8 HELLS	1.26e-04	130	68	4	35545047
Pubmed	Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor.	PTPN1 PTPN13	1.34e-04	9	68	2	12907755
Pubmed	Sensory inputs control the integration of neurogliaform interneurons into cortical circuits.	GRIN2B EMX1	1.34e-04	9	68	2	25664912
Pubmed	Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repair.	RNF40 CHD3	1.34e-04	9	68	2	25533843
Pubmed	A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.	EXOC6 CNNM1 SLF2 CLRN3 TET1 KCNMA1	1.63e-04	415	68	6	16385451
Pubmed	A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.	PTPN1 PTPN13	2.05e-04	11	68	2	7832766
Pubmed	The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3.	KIF3B KIF17	2.05e-04	11	68	2	9427749
Pubmed	Identification of a transient subpial neurogenic zone in the developing dentate gyrus and its regulation by Cxcl12 and reelin signaling.	EMX1 PROX1	2.05e-04	11	68	2	19103804
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	VPS13C ASH1L CHD6 KIF17	2.36e-04	153	68	4	10718198
Pubmed	A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation.	ATF4 NFAT5 SP140	2.37e-04	61	68	3	32911434
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	RDX MACF1 TOMM20 TLN2 RNF40 CHD3 PRPF6 RPL35	2.44e-04	847	68	8	35235311
Pubmed	Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport.	GRIN2B KIF17	2.45e-04	12	68	2	10846156
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TLK2 USP34 PTPN13 TUT7 TET1 ASH1L MACF1 CHD3 NFAT5	2.54e-04	1084	68	9	11544199
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NEK4 LIMK2 PTPN13 AKAP8 SLF2 TET1 NAV1 MACF1	2.72e-04	861	68	8	36931259
Pubmed	An investigation into the human serum "interactome".	EXOC6 KCNMA1 MACF1 TLN2	2.93e-04	162	68	4	15174051
Pubmed	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	SYNE1 OSBPL5	3.38e-04	14	68	2	20201924
Pubmed	Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system.	GRIN2B EMX1	3.38e-04	14	68	2	19240213
Pubmed	The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc.	GRIN2B EMX1	3.38e-04	14	68	2	32249816
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	PTPN1 ATG2B NAV1 KCNQ3 MACF1 TLN2 GRIN2B RPL35 CLEC16A	3.65e-04	1139	68	9	36417873
Pubmed	Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy.	ATG2B OSBPL5 CHD6	3.71e-04	71	68	3	33499712
Pubmed	A human MAP kinase interactome.	SYNE1 NAV1 MACF1 CHD6 ATF4 FMNL2	3.80e-04	486	68	6	20936779
Pubmed	A census of human transcription factors: function, expression and evolution.	HOXD12 NSD2 ASH1L ATF4 EMX1 NFAT5 ZFX PROX1	3.88e-04	908	68	8	19274049
Pubmed	DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression.	CHD3 EMX1	3.89e-04	15	68	2	35695185
Pubmed	DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation.	TCHH TET1	3.89e-04	15	68	2	36630508
Pubmed	An Early Cortical Progenitor-Specific Mechanism Regulates Thalamocortical Innervation.	EMX1 PROX1	4.44e-04	16	68	2	34193558
Pubmed	LDB1 Is Required for the Early Development of the Dorsal Telencephalon and the Thalamus.	EMX1 PROX1	4.44e-04	16	68	2	30873428
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SYNE1 NAV1 RDX KCNQ3 MACF1 TLN2 CHD3 GRIN2B RPL35 FMNL2	4.46e-04	1431	68	10	37142655
Pubmed	Engagement of the G3BP2-TRIM25 Interaction by Nucleocapsid Protein Suppresses the Type I Interferon Response in SARS-CoV-2-Infected Cells.	TCHH KCNQ3 DHX8	4.54e-04	76	68	3	36560452
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	PTPN13 GPATCH1 ATG2B RDX MACF1 CHD3 RPL35 HELLS	4.67e-04	934	68	8	33916271
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	HOXD12 TUT7 MACF1 ATF4 NFAT5 ZFX PROX1	4.69e-04	709	68	7	22988430
Pubmed	Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.	GPATCH1 KCNMA1 CDKAL1	5.08e-04	79	68	3	22504420
Pubmed	The DNA sequence and comparative analysis of human chromosome 20.	PTPN1 TRMT6 KIF3B GZF1 PRPF6 CHD6	5.26e-04	517	68	6	11780052
Pubmed	Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.	KCNQ3 EMX1	5.65e-04	18	68	2	37321992
Pubmed	Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity.	EMX1 PROX1	5.65e-04	18	68	2	35930666
Pubmed	Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development.	EMX1 PROX1	5.65e-04	18	68	2	21991391
Pubmed	The DNA sequence and comparative analysis of human chromosome 10.	SLF2 CLRN3 TET1 KCNMA1 HELLS	5.83e-04	345	68	5	15164054
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	STX8 PTPN1 PTPN13 AKAP8 SYNE1 MACF1 PRPF6 QRSL1 CDKAL1 HELLS	6.01e-04	1487	68	10	33957083
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	PTPN1 TRMT6 VPS13C SYNE1 TUT7 ATG2B ATXN3 NAV1 QRSL1 CDKAL1	6.30e-04	1496	68	10	32877691
Pubmed	Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation.	TOMM20 PROX1	6.30e-04	19	68	2	27246713
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PTPN13 GZF1 AKAP8 CWC27 ZNF277 NSD2 SYNE1 MACF1 CHD6 DHX8	6.33e-04	1497	68	10	31527615
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SYNE1 MACF1	7.00e-04	20	68	2	21689717
GeneFamily	PHD finger proteins	NSD2 ASH1L CHD3 SP140	1.20e-04	90	51	4	88
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF3B KIF27 KIF17	2.95e-04	46	51	3	622
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	PTPN13 RDX TLN2	3.77e-04	50	51	3	1293
GeneFamily	Protein tyrosine phosphatases, non-receptor type	PTPN1 PTPN13	1.16e-03	18	51	2	812
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	NSD2 ASH1L	4.13e-03	34	51	2	487
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	CNNM1 NSD2 VPS13C ATG2B MACF1 NFAT5	7.42e-06	180	68	6	M8239
Coexpression	GSE27786_BCELL_VS_NKCELL_UP	USP34 WDR64 AKAP8 TOMM20 CHD6 RPL35	1.35e-05	200	68	6	M4805
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000	TLK2 CLRN3 TET1 ASH1L CDKAL1 SENP7 HELLS	1.73e-05	259	67	7	gudmap_developingGonad_e12.5_epididymis_k3_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_1000	TLK2 NSD2 TET1 ASH1L CDKAL1 SENP7 HELLS	2.66e-05	277	67	7	gudmap_developingGonad_e12.5_ovary_k3_1000
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#2_top-relative-expression-ranked_200	TLK2 TET1 ASH1L HELLS	4.13e-05	61	67	4	gudmap_developingGonad_e12.5_epididymis_k2_200
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	NAPEPLD VPS13C ASH1L MACF1 NFAT5 CDKAL1 HELLS	1.44e-08	186	68	7	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 TET1 TLN2 GRIN2B EMX1 HELLS	3.36e-07	180	68	6	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	NAPEPLD VPS13C MACF1 NFAT5 CDKAL1 HELLS	3.95e-07	185	68	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 CHD3 EMX1 NFAT5 HELLS	6.24e-06	170	68	5	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 VPS13C ASH1L MACF1 NFAT5	1.02e-05	188	68	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A3 PTPN13 SYNE1 NFAT5 PROX1	1.04e-05	189	68	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 GRIN2B EMX1 NFAT5 HELLS	1.07e-05	190	68	5	11d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 GRIN2B EMX1 NFAT5 HELLS	1.07e-05	190	68	5	078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	VPS13C MACF1 NFAT5 CDKAL1 HELLS	1.10e-05	191	68	5	9454f642c3621370fa23640b631301346b300950
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP34 PTPN1 NFAT5 FMNL2 CDKAL1	1.15e-05	193	68	5	779276e775cb2492e8dd36436295a536084a6415
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 SYNE1 MACF1 CHD3 HELLS	1.27e-05	197	68	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TLK2 USP34 SYNE1 ASH1L MACF1	1.34e-05	199	68	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TLK2 USP34 VPS13C ASH1L MACF1	1.37e-05	200	68	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF27 NSD2 EMX1 PROX1	9.53e-05	156	68	4	4d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCell	Ionocyte-iono-1\|World / Class top	NAPEPLD KCNMA1 TLN2 KIF17	1.30e-04	169	68	4	4b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WDR64 SH3TC1 KIF17 PROX1	1.55e-04	177	68	4	76f5df101c693e5fa61554244d877fc8169ee66f
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLF2 SYNE1 TUT7 MACF1	1.55e-04	177	68	4	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLF2 SYNE1 TUT7 MACF1	1.55e-04	177	68	4	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	SLF2 SYNE1 TUT7 MACF1	1.55e-04	177	68	4	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SLF2 SYNE1 TUT7 MACF1	1.55e-04	177	68	4	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SLF2 SYNE1 TUT7 MACF1	1.55e-04	177	68	4	d5aeda113afaa2425874394610344570c9078478
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C SYNE1 TUT7 ASH1L	1.58e-04	178	68	4	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 TLN2 GRIN2B EMX1	1.72e-04	182	68	4	f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L MACF1 RPL35 SP140	1.72e-04	182	68	4	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WDR64 KIF17 CDKAL1 PROX1	1.72e-04	182	68	4	f231e86524b628e6e11ac33d5c34be99d454a92a
ToppCell	droplet-Spleen-nan-18m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L MACF1 RPL35 SP140	1.76e-04	183	68	4	28cbf909424f3be4491d49832f0aca0386560814
ToppCell	COVID-19_Mild-NK_activated\|COVID-19_Mild / Disease condition and Cell class	SLF2 SYNE1 TUT7 MACF1	1.76e-04	183	68	4	22bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L MACF1 RPL35 SP140	1.76e-04	183	68	4	3fa608aa6b119869ec3280dc388dfee57160e63a
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRMT6 GRIN2B EMX1 HELLS	1.87e-04	186	68	4	aeac0c2db173cd1ea45b5052ab418d6cacd198d8
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	SLF2 NSD2 TLN2 NFAT5	1.87e-04	186	68	4	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VPS13C KCNMA1 NAV1 GRIN2B	1.87e-04	186	68	4	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	SLF2 NSD2 TLN2 NFAT5	1.87e-04	186	68	4	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 GRIN2B EMX1 HELLS	1.91e-04	187	68	4	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 EMX1 NFAT5 HELLS	1.95e-04	188	68	4	e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 GRIN2B EMX1 HELLS	1.99e-04	189	68	4	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CNNM1 NAPEPLD NFAT5 CDKAL1	1.99e-04	189	68	4	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 GRIN2B EMX1 HELLS	1.99e-04	189	68	4	bfc76a72b600d641c8fe58346e5d8986c34f3981
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	SLF2 RNF40 CDKAL1 SP140	2.03e-04	190	68	4	651a1d3ae286e40f9d9f60e438211c6148d24143
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 GRIN2B EMX1 HELLS	2.03e-04	190	68	4	b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLF2 VPS13C TLN2 ANGPTL1	2.07e-04	191	68	4	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	facs-Diaphragm\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLN2 ATF4 RPL35 ANGPTL1	2.11e-04	192	68	4	486cbf9791ca619e307e8b18aa70ce22111f4f26
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	CNNM1 NAPEPLD NAV1 TLN2	2.11e-04	192	68	4	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN1 SH3TC1 MACF1 FMNL2	2.11e-04	192	68	4	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 TUT7 ASH1L MACF1	2.20e-04	194	68	4	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C ASH1L KCNMA1 ANGPTL1	2.24e-04	195	68	4	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	POLR1D PTPN1 KCNQ3 ATF4	2.29e-04	196	68	4	a6a52cafd7c9994bc3d2f68b15a1491cd96ef908
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PTPN13 SYNE1 MACF1 HELLS	2.29e-04	196	68	4	ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-41\|World / Primary Cells by Cluster	NAV1 CHD6 GRIN2B PROX1	2.29e-04	196	68	4	dee0984cd63a1a2fdebb4421af48ab566a5b684e
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	WDR64 TET1 ANGPTL1 SP140	2.29e-04	196	68	4	fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SYNE1 MACF1 CHD3 SP140	2.33e-04	197	68	4	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	(5)_Dendritic_cell-(53)_Lymphoid_DC\|(5)_Dendritic_cell / shred on Cell_type and subtype	TCHH EMX1 FMNL2 CLEC16A	2.38e-04	198	68	4	548da5fa86f9756c503ed77bcdde55bc4d1a2726
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	VPS13C SYNE1 ASH1L MACF1	2.38e-04	198	68	4	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	COVID_vent-Lymphocytic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	SYNE1 CHD3 RPL35 SP140	2.38e-04	198	68	4	ee80f647317377081b4bd194ee2801f556b3a53b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 KCNMA1 KCNQ3 GRIN2B	2.38e-04	198	68	4	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 KCNMA1 KCNQ3 GRIN2B	2.38e-04	198	68	4	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	(08)_Brush+PNEC\|World / shred by cell type by condition	NAV1 FMNL2 CDKAL1 PROX1	2.42e-04	199	68	4	f2e33cb569c25fc2732722cac295647e9bd8738f
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	USP34 KCNMA1 FMNL2 CDKAL1	2.42e-04	199	68	4	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 MACF1 EMX1 NFAT5	2.42e-04	199	68	4	3cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 ASH1L RDX MACF1	2.47e-04	200	68	4	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PTPN1 RDX RPL35 FMNL2	2.47e-04	200	68	4	5a3b04aaad9562636aa34750d6025e0fe0f9b2ba
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	PTPN1 VPS13C MACF1 ATF4	2.47e-04	200	68	4	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	mLN-Dendritic_cell-Lymphoid_DC\|Dendritic_cell / Region, Cell class and subclass	NAV1 CHD3 FMNL2 CLEC16A	2.47e-04	200	68	4	3813fa1ee1462ba83fd8b6253070f46f0b063084
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-cortical_neurons_2\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	KCNQ3 CHD3 EMX1 FMNL2	2.47e-04	200	68	4	0cb0755a101ec655359d051d6a8807408d727c55
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SYNE1 ASH1L MACF1 NFAT5	5.85e-05	50	46	4	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Disease	Intellectual Disability	TLK2 NSD2 SYNE1 ASH1L MACF1 CHD3 GRIN2B	7.64e-05	447	68	7	C3714756
Disease	diabetes mellitus biomarker	EXOC6 CDKAL1	2.33e-04	10	68	2	EFO_0006842
Disease	Drugs used in diabetes use measurement	EXOC6 MACF1 NFAT5 CDKAL1 PROX1	3.10e-04	255	68	5	EFO_0009924
Disease	alkaline phosphatase measurement	USP34 AKAP8 SLF2 GPATCH1 MACF1 CHD3 NFAT5 KIF17 SENP7	5.19e-04	1015	68	9	EFO_0004533
Disease	ankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis	KIF3B RDX CLEC16A CDKAL1 SP140	6.02e-04	295	68	5	EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
Disease	psoriasis, type 2 diabetes mellitus	RDX CDKAL1 PROX1	7.02e-04	75	68	3	EFO_0000676, MONDO_0005148
Disease	Schizophrenia	PTPN1 EFCAB11 TET1 NAV1 KCNQ3 ATF4 GRIN2B KIF17	9.43e-04	883	68	8	C0036341
Disease	cortical surface area measurement	USP34 EXOC6 STX8 PTPN1 TUT7 NAV1 MACF1 TLN2 FMNL2 CDKAL1	9.79e-04	1345	68	10	EFO_0010736
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	KIF27 TET1 MACF1 NFAT5 SENP7	1.53e-03	364	68	5	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	alpha fetoprotein measurement	USP34 TET1 SENP7	1.61e-03	100	68	3	EFO_0010583
Disease	bipolar disorder (is_implicated_in)	SYNE1 GRIN2B	2.04e-03	29	68	2	DOID:3312 (is_implicated_in)
Disease	chloride measurement	NFAT5 CDKAL1	2.04e-03	29	68	2	EFO_0009284
Disease	forced expiratory volume	KIF3B SYNE1 ATXN3 KCNMA1 NFAT5 CLEC16A ANGPTL1	2.24e-03	789	68	7	EFO_0004314

Protein segments in the cluster

Peptide	Gene	Start	Entry
QLKGDAQRYKRKLRE	RNF40	496	O75150
KRKKKYPQLRNRQDP	ASH1L	1271	Q9NR48
RREKQKYEALRKQQS	CWC27	361	Q6UX04
YIVNRNKKIEKRRQE	AKAP8	436	O43823
EQNKTAATRYRQKKR	ATF4	286	P18848
PKKKYTRRLREQQKT	GZF1	236	Q9H116
FKIKKINQRRYPRAT	ANGPTL1	26	O95841
PNYRSRRKKKLDSQN	ATG2B	1031	Q96BY7
KAGRDKYKTLRQIRQ	RDX	556	P35241
KLPKNKNRNRYRDVS	PTPN1	36	P18031
QEERQKLVRNIYKRK	HELLS	306	Q9NRZ9
QNRPKSRESRDKQKY	KCNMA1	1216	Q12791
RKNDRKKRYTVVGNP	LIMK2	496	P53671
PVKRNNAKYRRIQTL	KCNQ3	96	O43525
LRKRREAYFEKQQQK	ATXN3	281	P54252
PRQYKNQKESEKDLR	GPATCH1	326	Q9BRR8
SLKYANRARNIRNKP	KIF27	331	Q86VH2
RRDGKQYVIKKLNLR	NEK4	26	P51957
PENKARRNRKRSIKY	NSD2	161	O96028
QPDVDRVTKTYKRKN	MACF1	3061	O94854
NRNNDRKRAKEYKKE	FAM161B	521	Q96MY7
YNDNTEVPRKSRKRN	NFAT5	191	O94916
YRKQRKKQARLVLQP	EXOC6	306	Q8TAG9
KPSEDIYKNRQRRQQ	FAM157B	61	P0CG42
KQYREKRKQNPHSEN	QRSL1	146	Q9H0R6
DPRIAQKIKRFRNKQ	CHD6	341	Q8TD26
PKVRRRNTQKYLQEE	CDKAL1	36	Q5VV42
RRQSKRQLRNEKDKP	CHD3	1381	Q12873
RARKKRKPYTKQQIA	HOXD12	201	P35452
PDKARLLRQYDNEKK	FMNL2	46	Q96PY5
QNRRTKYKRQKLEEE	EMX1	241	Q04741
NIVRKKKEAQRYRNE	EFCAB11	81	Q9BUY7
KQKKQQRLEPLYNRY	DHX8	1191	Q14562
IGQTKENRRKNRYKN	PTPN13	2231	Q12923
AQKENYRQEKKRATR	OSBPL5	101	Q9H0X9
LRYANRAKNIRNKPR	KIF17	326	Q9P2E2
NQRDRNTLPKKGLRY	NAV1	936	Q8NEY1
PRKRSSQDKYEKRSN	POLR1D	106	P0DPB5
KTKRRLRNNLPDSQY	SENP7	301	Q9BQF6
NLKTKKQQRKERLYP	RPL35	101	P42766
NRLYDLPAKRREQQK	SYNE1	3201	Q8NF91
ARNKRQRNPRYEKLT	PRPF6	166	O94906
RESYRENKRKQKLPQ	PROX1	201	Q92786
YKRERAQKRRNSSIP	SLC9A3	681	P48764
NKRKRENEKQKQYPE	NANOGNB	91	Q7Z5D8
YRKQKNREKCAQVVP	SH3TC1	611	Q8TE82
KSSIERKYKPRQEQR	SLF2	276	Q8IX21
RKYKPRQEQRKQNDI	SLF2	281	Q8IX21
RDRRKKKPTVVSYQE	TET1	1156	Q8NFU7
KQNDQRNRKRKAEPY	TLK2	56	Q86UE8
YQKARYQRKQEQRKP	CLRN3	201	Q8NCR9
HKGKRRVQKRPNYKN	CLEC16A	381	Q2KHT3
LYTDNRKKQRVPQRE	CNNM1	571	Q9NRU3
LRYANRAKNIKNKPR	KIF3B	331	O15066
KEYQQKRREELSRQP	VPS13C	3496	Q709C8
QRNQYERKGEKAPKL	STX8	26	Q9UNK0
RGSKKDYIQEKQRRQ	TRMT6	336	Q9UJA5
KQHRKINPKNREYDR	ZNF277	246	Q9NRM2
QKPKKRRRPDSRQYQ	ZFX	396	P17010
YQNPRRNFRSLIEKK	ZNF69	76	Q9UC07
RNGDILEYKKKQRPQ	TLN2	76	Q9Y4G6
NSPRKRNQDKEKYQE	SP140	276	Q13342
KSTRPYLQRKDVKQA	USP34	3006	Q70CQ2
LNQRYPENKEKRSKE	TUT7	1376	Q5VYS8
RERQYRKDKKLQQKE	TCHH	956	Q07283
DPNFKNRLRERRKKQ	TOMM20	31	Q15388
PDVKNQDVKRFYRKL	WDR64	66	B1ANS9
YPKEAVRKRQNSARN	NAPEPLD	16	Q6IQ20
RKQQYKDSLKKRPAS	GRIN2B	1081	Q13224