Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	PRAMEF9 PRAMEF15 PRAMEF4 FZR1 BTRC PRAMEF11 PRAMEF6	1.60e-06	82	138	7	GO:1990756
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	PRAMEF9 PRAMEF15 PRAMEF4 FZR1 BTRC PRAMEF11 PRAMEF6	4.30e-06	95	138	7	GO:0140767
GeneOntologyMolecularFunction	frizzled binding	WNT3 WNT8A WNT2B WNT3A	1.99e-04	42	138	4	GO:0005109
GeneOntologyCellularComponent	cullin-RING ubiquitin ligase complex	FBXO48 PRAMEF9 PRAMEF15 FBXW4 PRAMEF4 FZR1 BTRC PRAMEF11 PRAMEF6	1.33e-05	212	140	9	GO:0031461
GeneOntologyCellularComponent	Cul2-RING ubiquitin ligase complex	PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	1.53e-05	47	140	5	GO:0031462
MousePheno	abnormal duodenum morphology	PRAMEF15 KIF16B PRAMEF4 RUNX1T1 SLC12A5 PRAMEF11 PRAMEF6	3.45e-07	64	100	7	MP:0003271
MousePheno	abnormal jejunum morphology	PRAMEF15 PRAMEF4 SLC12A5 PRAMEF11 PRAMEF6	1.03e-05	41	100	5	MP:0004002
Domain	ZnF_C2HC	FAM90A14 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10	1.94e-06	55	127	6	SM00343
Domain	Znf_CCHC	FAM90A14 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10	1.94e-06	55	127	6	IPR001878
Domain	Wnt	WNT3 WNT8A WNT2B WNT3A	7.30e-06	19	127	4	IPR005817
Domain	WNT1	WNT3 WNT8A WNT2B WNT3A	7.30e-06	19	127	4	PS00246
Domain	Wnt_CS	WNT3 WNT8A WNT2B WNT3A	7.30e-06	19	127	4	IPR018161
Domain	wnt	WNT3 WNT8A WNT2B WNT3A	7.30e-06	19	127	4	PF00110
Domain	PRAME_family	PRAMEF25 PRAMEF15 PRAMEF4 PRAMEF6	7.30e-06	19	127	4	IPR026271
Domain	WNT1	WNT3 WNT8A WNT2B WNT3A	7.30e-06	19	127	4	SM00097
Domain	Wnt3	WNT3 WNT3A	4.59e-05	2	127	2	IPR009141
Domain	TSP1	ADGRB2 SEMA5A SSPOP RSPO2 C8A	8.00e-05	65	127	5	SM00209
Domain	TSP1_rpt	ADGRB2 SEMA5A SSPOP RSPO2 C8A	8.00e-05	65	127	5	IPR000884
Domain	TSP1	ADGRB2 SEMA5A SSPOP RSPO2 C8A	8.00e-05	65	127	5	PS50092
Domain	GPS	ADGRG3 ADGRB2 ADGRG6 CELSR1	8.07e-05	34	127	4	SM00303
Domain	GPS	ADGRG3 ADGRB2 ADGRG6 CELSR1	9.07e-05	35	127	4	PF01825
Domain	GPS	ADGRG3 ADGRB2 ADGRG6 CELSR1	1.01e-04	36	127	4	PS50221
Domain	GPS	ADGRG3 ADGRB2 ADGRG6 CELSR1	1.13e-04	37	127	4	IPR000203
Domain	GPCR_2_extracellular_dom	ADGRG3 ADGRB2 ADGRG6 CELSR1	1.54e-04	40	127	4	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	ADGRG3 ADGRB2 ADGRG6 CELSR1	1.54e-04	40	127	4	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRG3 ADGRB2 ADGRG6 CELSR1	1.54e-04	40	127	4	PS50227
Domain	F-box-like	FBXO48 FBXW9 FBXW4 BTRC	2.24e-04	44	127	4	PF12937
Domain	7tm_2	ADGRG3 ADGRB2 ADGRG6 CELSR1	3.69e-04	50	127	4	PF00002
Domain	G_PROTEIN_RECEP_F2_2	ADGRG3 ADGRB2 ADGRG6 CELSR1	3.69e-04	50	127	4	PS00650
Domain	FBOX	FBXO48 FBXW9 FBXW4 BTRC	4.29e-04	52	127	4	SM00256
Domain	-	FBXW9 WDR31 FBXW4 SEMA5A WDFY4 FZR1 NWD2 BTRC PLXNA1	4.59e-04	333	127	9	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	FBXW9 WDR31 FBXW4 SEMA5A WDFY4 FZR1 NWD2 BTRC PLXNA1	4.79e-04	335	127	9	IPR015943
Domain	PH	CDC42BPG OBSCN ARHGEF18 PLEKHG4B ARHGEF40 PLEKHM2 OSBPL5 RASAL1	6.34e-04	278	127	8	SM00233
Domain	PH_DOMAIN	CDC42BPG OBSCN ARHGEF18 PLEKHG4B ARHGEF40 PLEKHM2 OSBPL5 RASAL1	6.49e-04	279	127	8	PS50003
Domain	PH_domain	CDC42BPG OBSCN ARHGEF18 PLEKHG4B ARHGEF40 PLEKHM2 OSBPL5 RASAL1	6.64e-04	280	127	8	IPR001849
Domain	PH_dom-like	CDC42BPG OBSCN ARHGEF18 WDFY4 PLEKHG4B ARHGEF40 MTMR4 PLEKHM2 OSBPL5 RASAL1	6.69e-04	426	127	10	IPR011993
Domain	GPCR_2_secretin-like	ADGRG3 ADGRB2 ADGRG6 CELSR1	7.41e-04	60	127	4	IPR000832
Domain	GPCR_2-like	ADGRG3 ADGRB2 ADGRG6 CELSR1	7.41e-04	60	127	4	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	ADGRG3 ADGRB2 ADGRG6 CELSR1	7.89e-04	61	127	4	PS50261
Domain	DH_1	OBSCN ARHGEF18 PLEKHG4B ARHGEF40	8.91e-04	63	127	4	PS00741
Domain	TSP_1	ADGRB2 SEMA5A SSPOP C8A	8.91e-04	63	127	4	PF00090
Domain	WD40_repeat_CS	FBXW9 WDR31 WDFY4 FZR1 NWD2 BTRC	9.01e-04	164	127	6	IPR019775
Domain	F-box	FBXO48 FBXW9 FBXW4 BTRC	1.12e-03	67	127	4	PF00646
Domain	RhoGEF	OBSCN ARHGEF18 PLEKHG4B ARHGEF40	1.32e-03	70	127	4	PF00621
Domain	DH_2	OBSCN ARHGEF18 PLEKHG4B ARHGEF40	1.32e-03	70	127	4	PS50010
Domain	-	OBSCN ARHGEF18 PLEKHG4B ARHGEF40	1.39e-03	71	127	4	1.20.900.10
Domain	DH-domain	OBSCN ARHGEF18 PLEKHG4B ARHGEF40	1.39e-03	71	127	4	IPR000219
Domain	-	CDC42BPG OBSCN ARHGEF18 PLEKHG4B ARHGEF40 MTMR4 PLEKHM2 OSBPL5 RASAL1	1.42e-03	391	127	9	2.30.29.30
Domain	FBOX	FBXO48 FBXW9 FBXW4 BTRC	1.47e-03	72	127	4	PS50181
Domain	Ptc/Disp	NPC1 PTCHD4	1.60e-03	9	127	2	IPR003392
Domain	Patched	NPC1 PTCHD4	1.60e-03	9	127	2	PF02460
Domain	F-box_dom	FBXO48 FBXW9 FBXW4 BTRC	1.71e-03	75	127	4	IPR001810
Domain	PTX	PTX4 ADGRG6	1.99e-03	10	127	2	SM00159
Domain	WD40	FBXW9 WDR31 FBXW4 WDFY4 FZR1 NWD2 BTRC	2.40e-03	268	127	7	SM00320
Domain	Pentaxin-related	PTX4 ADGRG6	2.42e-03	11	127	2	IPR001759
Domain	GAIN_dom_N	ADGRB2 CELSR1	2.42e-03	11	127	2	IPR032471
Domain	Pentaxin	PTX4 ADGRG6	2.42e-03	11	127	2	PF00354
Domain	GAIN	ADGRB2 CELSR1	2.42e-03	11	127	2	PF16489
Domain	WD40_repeat	FBXW9 WDR31 FBXW4 WDFY4 FZR1 NWD2 BTRC	2.61e-03	272	127	7	IPR001680
Domain	WD_REPEATS_1	FBXW9 WDR31 FBXW4 WDFY4 FZR1 NWD2 BTRC	2.94e-03	278	127	7	PS00678
Domain	WD_REPEATS_2	FBXW9 WDR31 FBXW4 WDFY4 FZR1 NWD2 BTRC	3.00e-03	279	127	7	PS50082
Domain	WD_REPEATS_REGION	FBXW9 WDR31 FBXW4 WDFY4 FZR1 NWD2 BTRC	3.00e-03	279	127	7	PS50294
Domain	SSD	NPC1 PTCHD4	3.41e-03	13	127	2	IPR000731
Domain	SSD	NPC1 PTCHD4	3.41e-03	13	127	2	PS50156
Domain	WD40_repeat_dom	FBXW9 WDR31 FBXW4 WDFY4 FZR1 NWD2 BTRC	4.23e-03	297	127	7	IPR017986
Domain	PH	CDC42BPG OBSCN ARHGEF18 PLEKHM2 OSBPL5 RASAL1	4.80e-03	229	127	6	PF00169
Domain	Kringle_CS	PRSS12 F2	5.84e-03	17	127	2	IPR018056
Domain	KRINGLE_1	PRSS12 F2	5.84e-03	17	127	2	PS00021
Domain	KR	PRSS12 F2	5.84e-03	17	127	2	SM00130
Domain	Kringle	PRSS12 F2	5.84e-03	17	127	2	IPR000001
Domain	KRINGLE_2	PRSS12 F2	5.84e-03	17	127	2	PS50070
Domain	Kringle	PRSS12 F2	5.84e-03	17	127	2	PF00051
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION	WNT3 WNT8A WNT2B WNT3A	5.60e-06	19	90	4	M47836
Pathway	REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING	WNT3 WNT8A WNT2B WNT3A	1.77e-05	25	90	4	MM14940
Pathway	REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING	WNT3 WNT8A WNT2B WNT3A	2.09e-05	26	90	4	M27239
Pathway	WNT_SIGNALING	WNT3 WNT8A WNT2B FBXW4 WNT3A BTRC	2.17e-05	89	90	6	M5493
Pathway	KEGG_HEDGEHOG_SIGNALING_PATHWAY	WNT3 WNT8A WNT2B WNT3A BTRC	2.80e-05	56	90	5	M1053
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR	WNT3 WNT8A WNT2B WNT3A	2.83e-05	28	90	4	M47835
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY	WNT3 WNT8A WNT2B WNT3A	3.27e-05	29	90	4	M47372
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY	WNT3 WNT8A WNT2B WNT3A	3.27e-05	29	90	4	M47377
Pathway	KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY	WNT3 WNT8A WNT2B WNT3A	8.73e-05	37	90	4	M47411
Pathway	WP_WNT_SIGNALING_IN_KIDNEY_DISEASE	WNT3 WNT2B WNT3A BTRC	1.73e-04	44	90	4	MM15878
Pathway	KEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY	WNT3 WNT8A WNT2B WNT3A	1.89e-04	45	90	4	M47412
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY	WNT3 WNT8A WNT2B WNT3A	2.07e-04	46	90	4	M47409
Pathway	KEGG_BASAL_CELL_CARCINOMA	WNT3 WNT8A WNT2B WNT3A	4.13e-04	55	90	4	M17807
Pathway	REACTOME_SIGNALING_BY_GPCR	GPBAR1 PDE4B WNT3 WNT8A WNT2B OBSCN ARHGEF18 XK F2 PTGER1 F2R ARHGEF40 WNT3A	4.92e-04	702	90	13	M746
Pubmed	Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	2.06e-20	25	146	11	17684299
Pubmed	Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.36e-18	23	146	10	18602769
Pubmed	Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.	FAM90A14 PKDCC FAM90A17 FAM90A19 FAM90A22 FAM90A26 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A10	1.16e-10	164	146	11	22967998
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NPC1 VWA5B2 USP34 OBSCN ADGRB2 MCM5 CLASP2 SBNO2 FAM83H FZR1 CELSR1 ARHGEF40 PLEKHM2 A4GALT OSBPL5 TIGD3 MAP3K11 PLEC SLC45A1 CABIN1 PLXNA1 RASAL1 PCNT	2.56e-10	1105	146	23	35748872
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	NLRP7 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	1.11e-07	28	146	5	25089626
Pubmed	Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury.	WNT3 WNT8A WNT2B WNT3A RSPO2	1.33e-07	29	146	5	22956684
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	NLRP7 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	1.59e-07	30	146	5	38786026
Pubmed	Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia.	WNT3 WNT8A WNT2B WNT3A RSPO2	1.59e-07	30	146	5	19282366
Pubmed	Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract.	WNT3 WNT8A WNT2B WNT3A RSPO2	1.59e-07	30	146	5	21936019
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	USP34 PRAMEF15 KIF16B PRAMEF4 ANKZF1 TRPM5 HPN PLEC CABIN1 PRAMEF11 PRAMEF6	4.29e-07	363	146	11	14691545
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	6.80e-07	17	146	4	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	6.80e-07	17	146	4	37781892
Pubmed	Wnt family proteins are secreted and associated with the cell surface.	WNT3 WNT8A WNT2B WNT3A	6.80e-07	17	146	4	8167409
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	8.71e-07	18	146	4	23894331
Pubmed	Restriction of Wnt signaling in the dorsal otocyst determines semicircular canal formation in the mouse embryo.	WNT3 WNT8A WNT2B WNT3A	8.71e-07	18	146	4	22166339
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	8.71e-07	18	146	4	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	8.71e-07	18	146	4	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	8.71e-07	18	146	4	14675769
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	8.71e-07	18	146	4	39181896
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	1.10e-06	19	146	4	28604677
Pubmed	Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis.	WNT3 WNT8A WNT2B WNT3A	1.10e-06	19	146	4	11520664
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	1.37e-06	20	146	4	26694250
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	1.37e-06	20	146	4	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	1.37e-06	20	146	4	21425410
Pubmed	Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.	WNT3 WNT8A WNT2B WNT3A RSPO2	1.62e-06	47	146	5	28813421
Pubmed	Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.	WNT3 WNT8A WNT2B CELSR1 WNT3A	1.62e-06	47	146	5	33141892
Pubmed	Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis.	WNT3 WNT8A WNT2B WNT3A	1.69e-06	21	146	4	17943183
Pubmed	The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium.	WNT3 WNT8A WNT2B WNT3A	1.69e-06	21	146	4	11914369
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	2.06e-06	22	146	4	31729367
Pubmed	Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.	WNT3 WNT8A WNT2B FBXW4 WNT3A BTRC	2.30e-06	90	146	6	19515997
Pubmed	Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models.	WNT3 WNT8A WNT2B WNT3A	2.48e-06	23	146	4	27362799
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	2.48e-06	23	146	4	19480014
Pubmed	Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate.	WNT3 WNT8A WNT3A	2.51e-06	7	146	3	18413325
Pubmed	Genome-wide association of serum uric acid concentration: replication of sequence variants in an island population of the Adriatic coast of Croatia.	SLC2A9 SEMA5A SLC28A2	2.51e-06	7	146	3	22229870
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	NPC1 USP34 PDE4B HK3 PRAMEF15 OBSCN ARHGEF18 CLASP2 PRAMEF4 WDFY4 SBNO2 PLEC CPLANE1 PRAMEF11 PRAMEF6 CSTPP1 PCNT	3.33e-06	1084	146	17	11544199
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	3.52e-06	25	146	4	37451217
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	3.52e-06	25	146	4	12620990
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	4.15e-06	26	146	4	18500982
Pubmed	ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6 PCNT	4.66e-06	58	146	5	31598710
Pubmed	Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections.	WNT3 WNT8A WNT2B WNT3A	4.85e-06	27	146	4	17804636
Pubmed	Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.	WNT3 WNT8A WNT2B WNT3A	5.64e-06	28	146	4	20940229
Pubmed	Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development.	WNT3 WNT8A WNT2B WNT3A	5.64e-06	28	146	4	24394376
Pubmed	3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19).	WNT3 WNT8A WNT2B WNT3A	6.52e-06	29	146	4	18364260
Pubmed	Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development.	WNT3 WNT8A WNT2B WNT3A	7.50e-06	30	146	4	15880404
Pubmed	Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development.	WNT3 WNT8A WNT2B WNT3A	7.50e-06	30	146	4	36305473
Pubmed	LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	9.78e-06	32	146	4	37889087
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRG3 ADGRB2 ADGRG6 CELSR1	1.11e-05	33	146	4	25713288
Pubmed	WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.	WNT3 WNT8A WNT2B WNT3A	1.41e-05	35	146	4	30940800
Pubmed	Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling.	WNT3 WNT8A WNT2B WNT3A	1.41e-05	35	146	4	23376422
Pubmed	Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation.	WNT3 WNT8A WNT2B WNT3A	1.41e-05	35	146	4	19185060
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	1.41e-05	35	146	4	19389355
Pubmed	Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea.	WNT3 WNT2B CELSR1 PCNT	1.41e-05	35	146	4	32907846
Pubmed	Gene trap screening as an effective approach for identification of Wnt-responsive genes in the mouse embryo.	WNT3 WNT2B WNT3A	1.55e-05	12	146	3	15778975
Pubmed	Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.	WNT3 WNT2B WNT3A RSPO2	1.58e-05	36	146	4	24151333
Pubmed	Platelets are activated in ANCA-associated vasculitis via thrombin-PARs pathway and can activate the alternative complement pathway.	F2 F2R	1.75e-05	2	146	2	29141676
Pubmed	Recombinant R-spondin2 and Wnt3a up- and down-regulate novel target genes in C57MG mouse mammary epithelial cells.	WNT3A RSPO2	1.75e-05	2	146	2	22238613
Pubmed	Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation.	F2 F2R	1.75e-05	2	146	2	1672265
Pubmed	Role of thrombin and its major cellular receptor, protease-activated receptor-1, in pulmonary fibrosis.	F2 F2R	1.75e-05	2	146	2	12023853
Pubmed	Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G, and proteinase 3: evidence for distinct cleavage sites within the aminoterminal domain of the thrombin receptor.	F2 F2R	1.75e-05	2	146	2	9058715
Pubmed	A critical role of thrombin/PAR-1 in ADP-induced platelet secretion and the second wave of aggregation.	F2 F2R	1.75e-05	2	146	2	23406164
Pubmed	Thrombin receptors on human platelets. Initial localization and subsequent redistribution during platelet activation.	F2 F2R	1.75e-05	2	146	2	9038223
Pubmed	Malfunction of respiratory-related neuronal activity in Na+, K+-ATPase alpha2 subunit-deficient mice is attributable to abnormal Cl- homeostasis in brainstem neurons.	SLC12A5 ATP1A2	1.75e-05	2	146	2	15564586
Pubmed	A role for oxysterol-binding protein-related protein 5 in endosomal cholesterol trafficking.	NPC1 OSBPL5	1.75e-05	2	146	2	21220512
Pubmed	Differential Ca(2+)responses induced by thrombin and thrombin-receptor agonist peptides in HSY-EA1 cells.	F2 F2R	1.75e-05	2	146	2	14642534
Pubmed	PAR-1 and thrombin: the ties that bind the microenvironment to melanoma metastasis.	F2 F2R	1.75e-05	2	146	2	22009534
Pubmed	The cleaved peptide of PAR1 is a more potent stimulant of platelet-endothelial cell adhesion than is thrombin.	F2 F2R	1.75e-05	2	146	2	12563219
Pubmed	Thrombin induced by the extrinsic pathway and PAR-1 regulated inflammation at the site of fracture repair.	F2 F2R	1.75e-05	2	146	2	26475502
Pubmed	N-linked glycosylation of protease-activated receptor-1 second extracellular loop: a critical determinant for ligand-induced receptor activation and internalization.	F2 F2R	1.75e-05	2	146	2	20368337
Pubmed	Regulation of WNT3 and WNT3A mRNAs in human cancer cell lines NT2, MCF-7, and MKN45.	WNT3 WNT3A	1.75e-05	2	146	2	11788904
Pubmed	Genetic Variants in WNT2B and BTRC Predict Melanoma Survival.	WNT2B BTRC	1.75e-05	2	146	2	28499756
Pubmed	Increased Pro-Thrombotic Platelet Activity Associated with Thrombin/PAR1-Dependent Pathway Disorder in Patients with Secondary Progressive Multiple Sclerosis.	F2 F2R	1.75e-05	2	146	2	33086557
Pubmed	Thrombin induces epithelial-mesenchymal transition via PAR-1, PKC, and ERK1/2 pathways in A549 cells.	F2 F2R	1.75e-05	2	146	2	23919450
Pubmed	Beta-TrCP recognizes a previously undescribed nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases.	CDC25B BTRC	1.75e-05	2	146	2	15845771
Pubmed	Protease activated receptor 1-induced glutamate release in cultured astrocytes is mediated by Bestrophin-1 channel but not by vesicular exocytosis.	BEST1 F2R	1.75e-05	2	146	2	23062602
Pubmed	Possible involvement of thrombin/protease-activated receptor 1 system in the pathogenesis of endometriosis.	F2 F2R	1.75e-05	2	146	2	15755869
Pubmed	Enhanced effector function of CD8(+) T cells from healthy controls and HIV-infected patients occurs through thrombin activation of protease-activated receptor 1.	F2 F2R	1.75e-05	2	146	2	23204166
Pubmed	Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube.	WNT3 WNT3A	1.75e-05	2	146	2	2001840
Pubmed	Thrombin Augments LPS-Induced Human Endometrial Endothelial Cell Inflammation via PAR1 Activation.	F2 F2R	1.75e-05	2	146	2	27108773
Pubmed	Integrated analysis of Wnt signalling system component gene expression.	WNT3 WNT8A WNT2B WNT3A	1.77e-05	37	146	4	35831952
Pubmed	Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.	WNT3 WNT8A WNT2B WNT3A	1.77e-05	37	146	4	15342465
Pubmed	Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.	WNT3 WNT8A WNT2B WNT3A	1.97e-05	38	146	4	21041481
Pubmed	Tissue-specific requirements of beta-catenin in external genitalia development.	WNT3 WNT8A WNT2B WNT3A	1.97e-05	38	146	4	18635608
Pubmed	Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis.	WNT3 WNT8A WNT2B WNT3A	1.97e-05	38	146	4	23190887
Pubmed	Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors.	WNT3 WNT8A WNT2B WNT3A	2.19e-05	39	146	4	24586192
Pubmed	Expression patterns of Wnt genes in mouse gut development.	WNT3 WNT8A WNT3A	3.18e-05	15	146	3	11429295
Pubmed	Expression and estradiol regulation of Wnt genes in the mouse blastocyst identify a candidate pathway for embryo-maternal signaling at implantation.	WNT3 WNT2B WNT3A	3.18e-05	15	146	3	15044261
Pubmed	Gpr177 regulates pulmonary vasculature development.	WNT3 WNT8A WNT2B WNT3A	3.55e-05	44	146	4	23884445
Pubmed	Molecular genetic studies of Wnt signaling in the mouse.	WNT3 WNT2B WNT3A	3.90e-05	16	146	3	10585256
Pubmed	The Wnts.	WNT3 WNT2B WNT3A	3.90e-05	16	146	3	9889131
Pubmed	c-Met and NF-κB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease.	WNT3 WNT2B WNT3A	3.90e-05	16	146	3	22677559
Pubmed	Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	4.24e-05	46	146	4	17287250
Pubmed	Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination.	WNT3 WNT8A WNT2B WNT3A	4.62e-05	47	146	4	16678101
Pubmed	Cooperative and independent functions of FGF and Wnt signaling during early inner ear development.	WNT3 WNT8A WNT3A	4.72e-05	17	146	3	26443994
Pubmed	Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.	WNT3 WNT8A WNT3A	4.72e-05	17	146	3	28733458
Pubmed	Protease-activated receptor-1 signaling by activated protein C in cytokine-perturbed endothelial cells is distinct from thrombin signaling.	F2 F2R	5.24e-05	3	146	2	15769747
Pubmed	Expression of thrombin and its associated protein in cerebellum of human and rat after intracerebral hemorrhage.	F2 F2R	5.24e-05	3	146	2	20819545
Pubmed	A novel protease-activated receptor-1 interactor, Bicaudal D1, regulates G protein signaling and internalization.	F2 F2R	5.24e-05	3	146	2	20164183
Pubmed	Wnt-3a and Wnt-3 differently stimulate proliferation and neurogenesis of spinal neural precursors and promote neurite outgrowth by canonical signaling.	WNT3 WNT3A	5.24e-05	3	146	2	20722074
Pubmed	Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin.	WNT3 WNT3A	5.24e-05	3	146	2	26902720
Pubmed	Engineering thrombin for selective specificity toward protein C and PAR1.	F2 F2R	5.24e-05	3	146	2	20404340
Cytoband	8p23.1	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	3.37e-12	154	147	11	8p23.1
Cytoband	Ensembl 112 genes in cytogenetic band chr8p23	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	3.07e-10	234	147	11	chr8p23
Cytoband	1p36.21	PRAMEF25 PRAMEF9 PRAMEF15 PRAMEF4 PLEKHM2 PRAMEF11 PRAMEF6	1.42e-09	63	147	7	1p36.21
Cytoband	1q42.13	IBA57 OBSCN TRIM11 PGBD5	1.91e-05	49	147	4	1q42.13
Cytoband	Ensembl 112 genes in cytogenetic band chr1p36	PRAMEF25 PRAMEF9 PRAMEF15 MMP23B PRAMEF4 FNDC10 PLEKHM2 SLC45A1 PRAMEF11 PRAMEF6	7.43e-05	681	147	10	chr1p36
Cytoband	Ensembl 112 genes in cytogenetic band chr1q42	IBA57 OBSCN TRIM11 WNT3A PGBD5	1.09e-03	240	147	5	chr1q42
GeneFamily	PRAME family	PRAMEF25 PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	1.31e-09	24	87	6	686
GeneFamily	Wnt family\|Endogenous ligands	WNT3 WNT8A WNT2B WNT3A	1.83e-06	19	87	4	360
GeneFamily	WD repeat domain containing\|F-box and WD repeat domain containing	FBXW9 FBXW4 BTRC	1.73e-05	11	87	3	559
GeneFamily	Adhesion G protein-coupled receptors, subfamily G	ADGRG3 ADGRG6	4.73e-04	7	87	2	917
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	CDC42BPG ARHGEF18 PLEKHG4B PLEKHM2 OSBPL5 RASAL1	4.77e-04	206	87	6	682
GeneFamily	WD repeat domain containing	FBXW9 WDR31 FBXW4 WDFY4 FZR1 BTRC	1.66e-03	262	87	6	362
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	OBSCN ARHGEF18 ARHGEF40	3.96e-03	66	87	3	722
Coexpression	GSE22589_HEALTHY_VS_HIV_INFECTED_DC_DN	SPATA18 IRF7 CEP128 FAM53C CFAP54 SLC28A2 TMCO3 C8A TRIM13	6.82e-07	200	129	9	M7807
Coexpression	DESCARTES_ORGANOGENESIS_SCHWANN_CELL_PRECURSOR	PRSS12 PRAMEF15 PRAMEF4 ADGRG6 PRAMEF11 PRAMEF6	9.19e-06	98	129	6	MM3656
Coexpression	KINNEY_DNMT1_METHYLATION_TARGETS	PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	2.32e-05	34	129	4	MM955
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Mesoderm\|10w / Sample Type, Dataset, Time_group, and Cell type.	FBXO48 GLDN TCIRG1 XK IRF7 MON1A PLEKHG4B SLC28A2 MRPL38	1.16e-08	200	136	9	9ef226ebb0a7cdb9431e2fa65faa2a7d67da590d
ToppCell	Biopsy_Control_(H.)-Immune-pDCs\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	NLRP7 IRF7 CLASP2 WDFY4 MILR1 FER1L6 SUSD1 TIGD3	1.58e-07	195	136	8	47d139215f0b51f5ea9b5fb09b1100e320e3f1e2
ToppCell	(7)_Epithelial-I_(AT1)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	TMEM63B PKDCC SEMA5A PLEKHG4B WNT3A PLXNA1 WWC1	2.43e-06	196	136	7	150554fa06868d29b0608189862eef6505ba757f
ToppCell	15-Airway-Mesenchymal-Mesenchyme_SERPINF1-high\|Airway / Age, Tissue, Lineage and Cell class	WNT2B SELENOM MMP23B PKDCC SEMA5A RUNX1T1 PTGER1	2.60e-06	198	136	7	3d76393e72eed59b4dd16130ef5dd1d331ba5711
ToppCell	MS-Multiple_Sclerosis-Myeloid-pDC\|Multiple_Sclerosis / Disease, condition lineage and cell class	NPC1 NLRP7 MMP23B IRF7 WDFY4 MILR1 SUSD1	2.69e-06	199	136	7	c10c8c9322cad4996e4aa11a8680e3d781644ace
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TMEM63B PKDCC FAAH CELSR1 PKHD1 PLXNA1 WWC1	2.69e-06	199	136	7	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	NLRP7 IRF7 WDFY4 MILR1 SUSD1 TIGD3	9.20e-06	158	136	6	2af7beb48272e5368d9ba6b80f08d47ab8556c08
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADGRG3 MMP23B TMEM63B PTCHD4 OSBPL5 PCNT	9.53e-06	159	136	6	7c2f70a7cba880115ccd676fb6c5f18488a5b74f
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	HK3 WDFY4 NEURL3 HPN SLC28A2	9.84e-06	93	136	5	1a112bd4e5e63826efad0338ce99d7a7ad9c72b9
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	HK3 WDFY4 NEURL3 HPN SLC28A2	9.84e-06	93	136	5	9c566fc2a8c7630bea28e8e46df55454aa409bc1
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	HK3 WDFY4 NEURL3 HPN SLC28A2	9.84e-06	93	136	5	d102a0a015a2866e3fe549ac8796b9a0d5923d7e
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	HK3 WDFY4 NEURL3 HPN SLC28A2	9.84e-06	93	136	5	0967a93dcc72d2d8f12d56de186ec1af55c36001
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	HK3 WDFY4 NEURL3 HPN SLC28A2	9.84e-06	93	136	5	613c827a643a7b6d70ef932cfa1762e90bc5a338
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Monophasic_Synovial_Sarcoma-5\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF11 PRAMEF6	9.84e-06	93	136	5	3e05ea0f8f4a7cdb78a596f47d563dc3c94d4d8e
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWA5B2 ADGRG3 SPATA18 ADGRB2 CFAP54 OR51Q1	1.35e-05	169	136	6	8bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDE4B NLRP7 IRF7 WDFY4 MILR1 SUSD1	1.39e-05	170	136	6	b49f7c8a27078de2137ed04f74cfee30729cfa5e
ToppCell	droplet-Kidney-nan-3m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS12 ACSM1 SSPOP FAM83H C8A WWC1	1.39e-05	170	136	6	dd48fd3c5c67eb71183981f42975a538f12077c3
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLDN SELENOM MMP23B PTCHD4 ARHGEF40 RSPO2	1.39e-05	170	136	6	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDE4B NLRP7 IRF7 WDFY4 MILR1 SUSD1	1.39e-05	170	136	6	92e765ae0d3adb38d3b22fddb873fd5ccad3fd44
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDE4B NLRP7 IRF7 WDFY4 MILR1 SUSD1	1.39e-05	170	136	6	9f8b215caa1afa3cd7104c06fca7cfd790640f66
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR31 SELENOM ETV2 ENTPD4 MTMR4 A4GALT	1.70e-05	176	136	6	2e9073166da4d9fae70ba4f3fdcad35523caf7cd
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NLRP7 IRF7 WDFY4 ZNF331 SUSD1 TIGD3	1.75e-05	177	136	6	8887ff6341eb070bdaa890cc2cd7745f0cf1b0af
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NLRP7 IRF7 WDFY4 ZNF331 SUSD1 TIGD3	1.75e-05	177	136	6	507f06d31ab773099c9431b6f433899dc97b5566
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PKDCC PLEKHG4B CELSR1 PKHD1 TRIM13 WWC1	1.75e-05	177	136	6	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	GLDN WDFY4 FNDC10 SUSD1 TMCO3 SLC45A1	1.81e-05	178	136	6	536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PKDCC PLEKHG4B CELSR1 PKHD1 TRIM13 WWC1	1.87e-05	179	136	6	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PKDCC SEMA5A PLEKHG4B CELSR1 PKHD1 WWC1	1.99e-05	181	136	6	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PKDCC ADGRG6 PLEKHG4B CELSR1 PKHD1 WWC1	2.32e-05	186	136	6	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PKDCC PLEKHG4B CELSR1 PKHD1 TRIM13 WWC1	2.32e-05	186	136	6	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A9 KIAA1671 CELSR1 PKHD1 C8A WWC1	2.32e-05	186	136	6	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5A ADGRG6 CELSR1 HPN PKHD1 WWC1	2.39e-05	187	136	6	9aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A9 KIAA1671 CELSR1 HPN PKHD1 WWC1	2.39e-05	187	136	6	3ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PKDCC PLEKHG4B CELSR1 PKHD1 TRIM13 WWC1	2.39e-05	187	136	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELENOM MMP23B SEMA5A RUNX1T1 PTGER1 RSPO2	2.54e-05	189	136	6	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A9 ACSM1 SEMA5A ADGRG6 PKHD1 WWC1	2.54e-05	189	136	6	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ACSM1 KIAA1671 PLEKHG4B CFAP54 PKHD1 WWC1	2.61e-05	190	136	6	625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A9 KIAA1671 CELSR1 HPN PKHD1 WWC1	2.69e-05	191	136	6	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A9 KIAA1671 CELSR1 HPN PKHD1 WWC1	2.69e-05	191	136	6	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELENOM MMP23B SEMA5A RUNX1T1 PTGER1 RSPO2	2.77e-05	192	136	6	ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCell	facs-Pancreas-Exocrine-3m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5A ADGRG6 CELSR1 HPN PKHD1 WWC1	2.85e-05	193	136	6	c3161a14a40323a58aa202c8a1d6ea0e9c2b9814
ToppCell	Striatum-Hematopoietic-MACROPHAGE\|Striatum / BrainAtlas - Mouse McCarroll V32	HK3 WDFY4 MILR1 NEURL3 HPN	3.12e-05	118	136	5	54930a3faa055bda4a707b93d790b2ac5a360211
ToppCell	Striatum-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)\|Striatum / BrainAtlas - Mouse McCarroll V32	HK3 WDFY4 MILR1 NEURL3 HPN	3.12e-05	118	136	5	18f9c1759df9504962612ec741638ed330c33222
ToppCell	Striatum-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Striatum / BrainAtlas - Mouse McCarroll V32	HK3 WDFY4 MILR1 NEURL3 HPN	3.12e-05	118	136	5	97db1193ecc885f63840663ab969468ce21cba74
ToppCell	Striatum-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--\|Striatum / BrainAtlas - Mouse McCarroll V32	HK3 WDFY4 MILR1 NEURL3 HPN	3.12e-05	118	136	5	0c2fe46dd66e0c9cdf8c2eb66874aca79592248a
ToppCell	Striatum-Hematopoietic-MACROPHAGE-MP1(C1qb)\|Striatum / BrainAtlas - Mouse McCarroll V32	HK3 WDFY4 MILR1 NEURL3 HPN	3.12e-05	118	136	5	3f8d11e09a7660af9eca5249ad698d9b638d39dd
ToppCell	Biopsy_IPF-Immune-pDCs\|Biopsy_IPF / Sample group, Lineage and Cell type	PDE4B NLRP7 MMP23B IRF7 WDFY4 FAM53C	3.29e-05	198	136	6	aa8943e6796f619406056cf763b751fe9a9a3e0c
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TMEM63B FAAH CELSR1 HPN PKHD1 WWC1	3.39e-05	199	136	6	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TMEM63B FAAH CELSR1 PKHD1 PLXNA1 WWC1	3.48e-05	200	136	6	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TMEM63B PKDCC FAAH CELSR1 PKHD1 WWC1	3.48e-05	200	136	6	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE4B PKDCC ADGRG6 NEURL3 RASAL1 WWC1	3.48e-05	200	136	6	7c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ADGRG3 CELSR1 TRPM5 TIGD3	6.27e-05	70	136	4	ee86e3790ff1fd684b7dff8c9de70e75133e9046
ToppCell	(01)_Cycling_Basal_(homeostasis)-(1)_24hpi\|(01)_Cycling_Basal_(homeostasis) / shred by cell type and Timepoint	MMP23B ADGRG6 PKHD1 C8A	6.63e-05	71	136	4	6aa56b0daaeb5e0ae30619f9c6945c8e42899b27
ToppCell	PND07-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC2A9 TCIRG1 WDFY4 NEURL3 RASAL1	8.05e-05	144	136	5	f5d0d0564fcbec8a5d87119e0807b619faa77b0f
ToppCell	droplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSM1 CPN2 F2 HPN C8A	8.87e-05	147	136	5	00619115b9a1ec2b967c2992043b41974ece63c4
ToppCell	Frontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Igsf8_(Ctps)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FBXO48 SPATA18 SSPOP PKHD1	1.01e-04	79	136	4	eddad041c0bc6952d9c68a36bdd78f6d661f0e58
ToppCell	Frontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Igsf8_(Ctps)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FBXO48 SPATA18 SSPOP PKHD1	1.01e-04	79	136	4	4c9c3051cb8a9c39c6df20e3fe37242db4b44280
ToppCell	Striatum-Hematopoietic\|Striatum / BrainAtlas - Mouse McCarroll V32	HK3 WDFY4 MILR1 NEURL3 HPN	1.14e-04	155	136	5	12301d823338bf829475905c66c5f08f7159d29f
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDFY4 SRPX2 PLEKHM2 SLC28A2 PLXNA1	1.21e-04	157	136	5	ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	TCIRG1 MILR1 FAM83H ADGRG6 ATP1A2	1.21e-04	157	136	5	2c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PKDCC CEP128 PLEKHG4B PKHD1 GVQW3	1.21e-04	157	136	5	4766f7d545bf2d775390589460677519cb92f4d5
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	MMP23B PKDCC WNT3A PLEC PLXNA1	1.32e-04	160	136	5	58ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCell	Children_(3_yrs)-Immune-dendritic_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDE4B ETV2 IRF7 CEP128 WDFY4	1.40e-04	162	136	5	86a0b9dabd150dc993bfc0f3344804de7f8e4042
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IBA57 CPN2 CELSR1 SUSD1 SLC28A2	1.44e-04	163	136	5	4af92b211d12c5b88b65bb746242cd702b545bd0
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDFY4 SRPX2 PLEKHM2 SLC28A2 PLXNA1	1.44e-04	163	136	5	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDFY4 SRPX2 PLEKHM2 SLC28A2 PLXNA1	1.44e-04	163	136	5	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IBA57 CPN2 CELSR1 SUSD1 SLC28A2	1.44e-04	163	136	5	d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRM2 SELENOM MMP23B NUP98 MCM5	1.57e-04	166	136	5	49103b75c3e08656c5774f56fd00d7bd53eefcfb
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	XK F2R FNDC10 TMTC4 KLHDC8B	1.61e-04	167	136	5	b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCell	Tuft-tuft-1\|World / Class top	ADGRG3 SELENOM ADGRB2 SBNO2 TRPM5	1.66e-04	168	136	5	8ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 WDFY4 SRPX2 PLEKHM2 PLXNA1	1.66e-04	168	136	5	04e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM63B MCM5 CELSR1 TRIM13 FCHSD1	1.66e-04	168	136	5	ca65321259711321c175ede67bd67a47aad81d7a
ToppCell	390C-Myeloid-Dendritic-pDC\|390C / Donor, Lineage, Cell class and subclass (all cells)	NLRP7 IRF7 MILR1 SUSD1 TIGD3	1.66e-04	168	136	5	5a2e7a52b7330dce30823695a7b9b26bc47a69ce
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADGRG6 CFAP54 PKHD1 RASAL1 WWC1	1.66e-04	168	136	5	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GPBAR1 SELENOM PTCHD4 F2R ADGRG6	1.75e-04	170	136	5	1f994b690e881106a5d54b3080ccce6260bc3ac5
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5A ADGRG6 HPN PKHD1 WWC1	1.80e-04	171	136	5	5447b78148f7bccb727e2fc108589b2af02a5d31
ToppCell	COVID-pDC\|COVID / Condition, Cell_class and T cell subcluster	NLRP7 MMP23B IRF7 PLEKHG4B SUSD1	1.85e-04	172	136	5	3ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5A ADGRG6 HPN PKHD1 WWC1	1.85e-04	172	136	5	a7eee0a30d2fe20c865a07b9004c6a821a72c0c4
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5A ADGRG6 HPN PKHD1 WWC1	1.85e-04	172	136	5	0a9fe2cd28203970295a1288078c66eadac1c9ed
ToppCell	COVID-pDC-\|COVID / Condition, Cell_class and T cell subcluster	NLRP7 MMP23B IRF7 PLEKHG4B SUSD1	1.85e-04	172	136	5	a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADGRG3 NLRP7 XK SACM1L OSBPL5	1.85e-04	172	136	5	e3a8891694343b6b01e80a200ae338d24797e417
ToppCell	URO-Myeloid-cDC1\|URO / Disease, Lineage and Cell Type	KIF16B MCM5 WDFY4 FAAH ADGRG6	1.90e-04	173	136	5	57f4e9f39ef6e02dca76f3dd0b39a0871917ed5a
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADGRB2 IRF7 CELSR1 CDC25B RASAL1	1.90e-04	173	136	5	da0f1461643294f92e20b5e456a50211a2780a91
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWA5B2 SELENOM SPATA18 CHRND HPN	1.95e-04	174	136	5	b4483d7d9f22f09ed7fa0b72305434a47ccaade0
ToppCell	10x5'-blood-Myeloid_Dendritic\|blood / Manually curated celltypes from each tissue	NLRP7 IRF7 WDFY4 ADGRG6 PLEKHG4B	2.01e-04	175	136	5	1c48eec300d5a6d4a810947b995af3b8c0a5a601
ToppCell	facs-Marrow-T_cells-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT3 SELENOM FAAH CHRND A4GALT	2.01e-04	175	136	5	4be01bf30331162f1998216fb2871a4e626dc440
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	VWA5B2 GPBAR1 ADGRG3 SLC12A5 A4GALT	2.01e-04	175	136	5	9941c35601134d88d1b3249c81f8b43a8fc61610
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WNT3 ACSM1 PTCHD4 SLC45A1 PLXNA1	2.01e-04	175	136	5	19eda8b5d39dc93d79737ebdbeeba5ec0cb23c51
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	USP49 CEP128 FNDC10 RSPO2 PLXNA1	2.11e-04	177	136	5	30f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	GLDN PKDCC FNDC10 TMCO3 SLC45A1	2.17e-04	178	136	5	9d575902d3dbe33437c9d4200df093a741269803
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NLRP7 IRF7 WDFY4 ZNF331 SUSD1	2.23e-04	179	136	5	c9f45cfea0ceb0cdc31bcfd123aeab69aeb35c35
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRSS12 MMP23B SRPX2 NWD2 RSPO2	2.29e-04	180	136	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	moderate-Myeloid-pDC\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NLRP7 MMP23B IRF7 WDFY4 SUSD1	2.29e-04	180	136	5	a0751ad5e42a21cb107d900abfa9ee967a0069fc
ToppCell	3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NLRP7 IRF7 WDFY4 MILR1 SUSD1	2.29e-04	180	136	5	6a2366d76276452141db1bd93013a9503525f574
ToppCell	NS-moderate-d_16-33-Myeloid-pDC\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NLRP7 MMP23B IRF7 WDFY4 SUSD1	2.29e-04	180	136	5	144818e69613296cde43f29cb8c20899c670b319
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP23B PTCHD4 PTGER1 ADGRG6 OSBPL5	2.29e-04	180	136	5	6327c938a4f99df9fee714e44f15ea4a4a63ae15
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CELSR1 TRPM5 SLC28A2 TIGD3	2.32e-04	98	136	4	fca0baf13520c53edb6da2fe3eb152fbd44df5ed
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRSS12 MMP23B PTGER1 NWD2 RSPO2	2.34e-04	181	136	5	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	wk_20-22-Hematologic-Myeloid-pDC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NPC1 NLRP7 IRF7 WDFY4 SUSD1	2.34e-04	181	136	5	60607c5ff6d5b1cb416adc034491dca31c41e988
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PRSS12 FER1L6 PLEKHG4B CELSR1 WWC1	2.40e-04	182	136	5	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	facs-Pancreas-Exocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5A CELSR1 HPN PKHD1 WWC1	2.40e-04	182	136	5	45faefd7cbeac84d2c58650530b902af6ce921f8
Disease	Tetraamelia multiple malformations	WNT3 RSPO2	1.70e-05	2	122	2	C2931218
Disease	prothrombin measurement	F2 CSTPP1	1.01e-04	4	122	2	EFO_0020692
Disease	cortical thickness	VWA5B2 GDF5-AS1 GPBAR1 PRSS12 WNT3 PKDCC RUNX1T1 SACM1L CELSR1 ARHGEF40 WNT3A PKHD1 RSPO2 PLEC	2.11e-04	1113	122	14	EFO_0004840
Disease	protocadherin alpha-7 measurement	CPN2 CPNE1	3.51e-04	7	122	2	EFO_0801973
Disease	lethal congenital contracture syndrome (is_implicated_in)	GLDN ADGRG6	3.51e-04	7	122	2	DOID:0060558 (is_implicated_in)
Disease	protein FAM163B measurement	CPN2 CPNE1	5.99e-04	9	122	2	EFO_0802936
Disease	cell growth regulator with EF hand domain protein 1 measurement	CPN2 CPNE1	9.10e-04	11	122	2	EFO_0801461
Disease	3-hydroxyanthranilate 3,4-dioxygenase measurement	CPN2 CPNE1	9.10e-04	11	122	2	EFO_0021862
Disease	neuroimaging measurement	VWA5B2 GDF5-AS1 PRSS12 WNT3 PKDCC RUNX1T1 CELSR1 PKHD1 RSPO2 MAP3K11 PLEC WWC1	1.61e-03	1069	122	12	EFO_0004346
Disease	complement factor H-related protein 1 measurement	CPN2 CENPVL2 CPNE1	1.63e-03	56	122	3	EFO_0600054
Disease	brain edema (biomarker_via_orthology)	F2 F2R	1.72e-03	15	122	2	DOID:4724 (biomarker_via_orthology)
Disease	idiopathic scoliosis (implicated_via_orthology)	SSPOP ADGRG6	1.96e-03	16	122	2	DOID:0060250 (implicated_via_orthology)
Disease	brain measurement, neuroimaging measurement	VWA5B2 GDF5-AS1 WNT2B PKDCC RUNX1T1 SACM1L RSPO2 PLEC	2.09e-03	550	122	8	EFO_0004346, EFO_0004464
Disease	gait measurement	NPC1 ADGRB2 MON1A BTRC	3.54e-03	150	122	4	EFO_0007680
Disease	reticulocyte count	USP49 USP34 GPBAR1 TCIRG1 F2R SBNO2 SLC12A5 FZR1 SUSD1 A4GALT SLC45A1	4.10e-03	1045	122	11	EFO_0007986

Protein segments in the cluster

Peptide	Gene	Start	Entry
TFNLCLSLAGWRRTF	BTN2A3P	281	Q96KV6
LCSKTCDTGWQRRFR	ADGRB2	486	O60241
SWNRVARTVDRLCLF	CHRND	461	Q07001
ERSRSCSESWRRLSL	ARHGEF18	81	Q6ZSZ5
EFRRRCATSLFNIWT	CFAP54	101	Q96N23
FRCRDRLSPWAARST	CEP128	11	Q6ZU80
QEWDLRSSCGSLRLT	CPN2	521	P22792
GTWAAALSARERLRS	ARHGEF40	1121	Q8TER5
SSWSVCRAGIQERRR	C8A	546	P07357
WCSIRSLAESRACRG	A4GALT	261	Q9NPC4
CGRFRLADNSDWSKT	ADGRG6	1131	Q86SQ4
QWCKFQSESTGRRAR	GVQW3	171	Q3ZCU0
TIESNWRCGRHSLQR	BTRC	281	Q9Y297
AAWACFRLDGRTLLR	IBA57	46	Q5T440
RENRTSLELCWFREG	ADGRG3	411	Q86Y34
FALCQWRGLSSALRA	GLDN	36	Q6ZMI3
NARLGSFSRLLLCWR	BEST1	11	O76090
ERWETFRKLRGLSCE	CENPVL1	101	A0A0U1RR11
WSARGCELLSRNRTH	CELSR1	2426	Q9NYQ6
FRRLENGRWSSSLLA	FAM90A10	396	A6NDY2
CEGLFSRINETTRWD	KIF16B	126	Q96L93
SRVWRLATGHRVCNI	NWD2	1421	Q9ULI1
FRSARWTCCLQAERS	RASAL1	686	O95294
FRRACLSGGTQRDWS	RFT1	66	Q96AA3
FRRLENGRWSSSLLA	FAM90A7	396	A6NKC0
LRRERSVAQFLSWAS	CDC42BPG	41	Q6DT37
FRRLENGRWSSSLLA	FAM90A23	396	A8MXZ1
SLCLSGSRDRNVNLW	FBXW9	186	Q5XUX1
SGKETRFLQCSRRQW	PRSS12	456	P56730
ERRRAFSRWLSCTAT	NUP98	1301	P52948
WITGCSRKRALQDRT	HDX	426	Q7Z353
WASRRSVRKCISLFR	KIAA1671	431	Q9BY89
RCSVLAAANSVFGRW	MCM5	481	P33992
CWSDVVGRRSSLLAC	MFSD9	101	Q8NBP5
SLAEVCRSGERSTRW	WWC1	766	Q8IX03
CRSGERSTRWYNLLS	WWC1	771	Q8IX03
RNTWRALSLVIGDCR	RUNX1T1	6	Q06455
QRCLQGLWGRASRDS	GPBAR1	296	Q8TDU6
GAFWNSVRSVSRCRS	SPATA18	491	Q8TC71
FRRLENGRWSSSLLA	FAM90A22	396	A8MWA6
FRRLENGRWSSSLLA	FAM90A14	396	P0C7W9
CSFSWRNSREIRCLT	PLXNA1	1001	Q9UIW2
LLWFNVRRISSEACF	OR51Q1	86	Q8NH59
CNTLSGLALLRARWR	PTGER1	221	P34995
SSNTLGIDLWRGRRC	PDE4B	31	Q07343
LRGSWRSRFQRALAC	FAM236A	51	A0A1B0GUQ0
DIRSLCRASLTCRSW	FBXO48	51	Q5FWF7
CRASLTCRSWNDTIR	FBXO48	56	Q5FWF7
GTLCWSRFAQIRAEL	PRAMEF15	426	P0DUQ1
TRSWAGERSRRELCS	CDC25B	561	P30305
EARRGWRLFNCSASL	LAS1L	446	Q9Y4W2
AERAGWKTNFRCALR	IRF7	86	Q92985
FRRLENGRWSSSLLA	FAM90A17	396	P0DV74
FRRLENGRWSSSLLA	FAM90A16	396	P0DV73
LDRSTLISWTKGFRC	HK3	176	P52790
ALREECTRLWSRGEA	PCNT	1381	O95613
FRRLENGRWSSSLLA	FAM90A19	396	P0DV76
FDKTEGTWRLLCSSR	HPN	66	P05981
GTWRLLCSSRSNARV	HPN	71	P05981
NRLLFWSIFSSVTCR	MILR1	6	Q7Z6M3
QCQEWLSRLSRATAR	MTMR4	106	Q9NYA4
LSWRTLGRASFTCLA	F2R	211	P25116
FEGCLRRLFTRWGSF	NPC1	331	O15118
CRLSRASGQEARWAL	OBSCN	4271	Q5VST9
RKFSLWVRQCSSTGF	PGBD5	281	Q8N414
FRRLENGRWSSSLLA	FAM90A8	396	A6NJQ4
DSRGRTVFGAWRCLL	FCHSD1	76	Q86WN1
GTFCASWTPLRNRRA	MON1A	81	Q86VX9
GTADRCIRFWNTLTG	FZR1	376	Q9UM11
WTALSRIAGLCNRAV	ATP1A2	416	P50993
RRSWCCNSDGALLRF	CABIN1	901	Q9Y6J0
VSFLRAFWRCFRTVG	CSTPP1	76	Q9H6J7
ERWETFRKLRGLSCE	CENPVL2	101	P0DPI3
IRWSNRRLLCDSGIT	CPLANE1	1751	Q9H799
AIVNTRRCWSCGASL	ANKZF1	681	Q9H8Y5
LRGSWRSRFQRALAC	FAM236B	51	A0A1B0GV22
RRVRAFALNCSWRGA	FNDC10	101	F2Z333
RDNGFCSWLTAIFRI	TMEM63B	121	Q5T3F8
TRNRAFSWTCRAARS	GDF5-AS1	76	Q5U4N7
FTSCDLLWRRIARAS	FBXW4	61	P57775
GRRRKDWSCSLLVAS	SLC2A9	46	Q9NRM0
LGSVESFSLARRRWE	KLHDC8B	296	Q8IXV7
CFVAAAVALRWSGRR	FAAH	21	O00519
FRRLENGRWSSSLLA	FAM90A20P	396	A6NIJ5
AGLRRWRLASYLSGC	FAM83H	576	Q6ZRV2
RSSCIRWTGNSREFQ	ETV2	256	O00321
LRGSWRSRFQRALAC	FAM236C	51	P0DP71
LRGSWRSRFQRALAC	FAM236D	51	A0A1B0GTK5
FRRLENGRWSSSLLA	FAM90A5P	396	A8MXJ8
WGRQALSKRTLCQRD	FAM53C	366	Q9NYF3
VWRELGCLSRTASFA	SAMM50	231	Q9Y512
FDWILISRRSCFRAG	SACM1L	206	Q9NTJ5
QPLLGAWSDRCTSRF	SLC45A1	171	Q9Y2W3
RLEDSSNGERRACWA	MAP3K11	551	Q16584
WAELGRTERVRNCSS	CPNE1	41	Q99829
FRRLENGRWSSSLLA	FAM90A24P	396	P0C7X0
WSCRALRRKSRNLFS	HEXA-AS1	76	Q9H8Q6
ALSFCSWVRTASGRL	PTX4	296	Q96A99
VTTRLWGLFCSSRFL	SLC12A5	336	Q9H2X9
LIFRAASESDGRCWL	OSBPL5	221	Q9H0X9
AWQRSDSLCRGRASR	PLEKHM2	1001	Q8IWE5
LSICVVDWRAFGRST	FER1L6	1061	Q2WGJ9
AECSRSRARAGELWL	QTRT1	21	Q9BXR0
QTSWEDRFRICLSLG	PKDCC	246	Q504Y2
WNRLSGLTRARVETC	SELENOM	31	Q8WWX9
LCLQGTRSRTLGDSW	SSPOP	4216	A2VEC9
SRQWVRDSCRKLSGL	TMCO3	46	Q6UWJ1
LDRLFVCASWARRGF	MMP23B	256	O75900
FRRLENGRWSSSLLA	FAM90A12P	396	A8MX19
CATKWSILRERFDRG	ENTPD4	461	Q9Y227
FRRLENGRWSSSLLA	FAM90A9	396	A6NNJ1
FRRLENGRWSSSLLA	FAM90A13P	396	P0C7W8
DDLRRLCSGFTAVSW	PTCHD4	536	Q6ZW05
FRRLENGRWSSSLLA	FAM90A26	396	D6RGX4
GTLCWSRFTQIRAEL	PRAMEF25	426	A6NGN4
RTRLRQILDWCGEAF	SBNO2	366	Q9Y2G9
QDLRSLRLWTDFCSL	NLRP7	656	Q8WX94
CIRGWASSALVFTSR	PKHD1	1721	P08F94
TQGNFSLQFCRRWSR	PKHD1	1916	P08F94
RTCGFKWGLETRTRQ	RSPO2	161	Q6UXX9
FRRLENGRWSSSLLA	FAM90A15P	396	P0C7V4
QRRSRWPFSKARSFC	SLC28A2	56	O43868
TSWSQCSRDCSRGIR	SEMA5A	791	Q13591
QLRCRSLSEFGAPRW	ACSM1	26	Q08AH1
RCASSNWSERKEGLL	CLASP2	661	O75122
GTLCWSRFAQIRAEL	PRAMEF4	426	O60810
DADGTLCWSRFAQIR	PRAMEF6	421	Q5VXH4
FINTLRCVLRSGEWR	TMTC4	451	Q5T4D3
LADWCSGTANRERKR	TIGD3	56	Q6B0B8
RALGTLRRWFECNST	TIGD3	436	Q6B0B8
RTSWALGVCRENVNR	TRIM11	351	Q96F44
LQLWIRGNVSACARS	TOR1A	151	O14656
FQSFETWRRGDALSR	TRIM13	146	O60858
CECRRWRGFSTSAVL	MRPL38	11	Q96DV4
FALLVRRNRCWSKTT	TRPM5	596	Q9NZQ8
RSVQCLPSRRWSGTA	SRPX2	101	O60687
REGELARWTRSSELC	PLEKHG4B	511	Q96PX9
ISNISGFNETCLRWR	SUSD1	496	Q6UWL2
GTLCWSRFAQIRAEL	PRAMEF9	426	P0DUQ2
EREGFCWNGRASISR	USP49	326	Q70CQ1
CWNGRASISRSLELI	USP49	331	Q70CQ1
LRTRFRDGLCAGSWV	WDFY4	1656	Q6ZS81
NSDRRSKSLGRNWIC	ZNF331	71	Q9NQX6
GRRWNCTTIDDSLAI	WNT3	86	P56703
GTLCWSRFAQIRAEL	PRAMEF11	426	O60813
RCDNFTSSWRDGRLF	PLEC	316	Q15149
FLCKTWAGSQSRRLQ	MRM2	191	Q9UI43
CALTGDLVRFWVDRR	NEURL3	116	Q96EH8
ASGELWDRLRLTCSR	XNDC1N	121	Q6ZNB5
ARRCWLRALQTSKVS	VWA5B2	916	Q8N398
FRGRRWNCTTVHDSL	WNT3A	81	P56704
NITRSGIECQLWRSR	F2	121	P00734
LDGRSCWTTLISAFR	USP34	2936	Q70CQ2
NTSRWERRSCGRLCT	WNT8A	281	Q9H1J5
GCEATLWDLRQTRNR	WDR31	256	Q8NA23
GRDWLRSQSSRCSRA	nan	171	Q6ZS46
SSSVSEGFQRWLRCF	XK	381	P51811
CTLRTCWRALSDFRR	WNT2B	246	Q93097
LWRACRGFLIASFRE	TCIRG1	186	Q13488
FRRLENGRWSSSLLA	FAM90A18	396	P0DV75