Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	transport along microtubule	KIF21B MAP1B MYO5A DYNC2H1 IFT74 SPG11 CCDC38 DST SYNE2 BBS12	4.12e-06	197	164	10	GO:0010970
GeneOntologyBiologicalProcess	cytoskeleton-dependent intracellular transport	KIF21B MAP1B MYO5A DYNC2H1 IFT74 SPG11 CCDC38 DST SYNE2 BBS12	1.33e-05	225	164	10	GO:0030705
GeneOntologyBiologicalProcess	microtubule-based transport	KIF21B MAP1B MYO5A DYNC2H1 IFT74 SPG11 CCDC38 DST SYNE2 BBS12	3.63e-05	253	164	10	GO:0099111
GeneOntologyBiologicalProcess	microtubule-based movement	CFAP47 KIF21B DNAH10 MAP1B MYO5A DYNC2H1 IFT74 SPG11 CCDC38 DST CELSR2 SYNE2 BBS12 HYDIN	4.14e-05	493	164	14	GO:0007018
GeneOntologyCellularComponent	insulin-responsive compartment	MYO5A DENND4C AKT2	7.61e-05	11	165	3	GO:0032593
GeneOntologyCellularComponent	myosin complex	MYO5A MYO9A BMF MYH16 MYO15A	1.02e-04	59	165	5	GO:0016459
HumanPheno	Cerebellar hypoplasia	MPL ROGDI CCDC22 ERCC6 POLR1A MYO5A DYNC2H1 IFT74 EVC BUB1 VPS35L MACF1 HERC1 EXOC7 POMK ALG6 PLK4 VPS13B FOXC1	9.10e-06	530	62	19	HP:0001321
MousePheno	abnormal skin coloration	MYO5A CES1 FRYL ITGB8 QSOX1 DST NF1 ADAMTS20 CTLA4 TARBP1	6.13e-06	182	127	10	MP:0011239
Domain	Spectrin	SPTAN1 SPTBN5 DST SYNE2 MACF1	1.37e-06	23	162	5	PF00435
Domain	ACTININ_2	SPTBN5 DST CLMN SYNE2 MACF1	1.37e-06	23	162	5	PS00020
Domain	ACTININ_1	SPTBN5 DST CLMN SYNE2 MACF1	1.37e-06	23	162	5	PS00019
Domain	Actinin_actin-bd_CS	SPTBN5 DST CLMN SYNE2 MACF1	1.37e-06	23	162	5	IPR001589
Domain	CH	CFAP47 SPTBN5 DST CLMN SYNE2 MACF1 CNN1	2.46e-06	70	162	7	PF00307
Domain	-	CFAP47 SPTBN5 DST CLMN SYNE2 MACF1 CNN1	2.71e-06	71	162	7	1.10.418.10
Domain	CH	CFAP47 SPTBN5 DST CLMN SYNE2 MACF1 CNN1	3.27e-06	73	162	7	PS50021
Domain	CH-domain	CFAP47 SPTBN5 DST CLMN SYNE2 MACF1 CNN1	3.92e-06	75	162	7	IPR001715
Domain	Spectrin_repeat	SPTAN1 SPTBN5 DST SYNE2 MACF1	4.63e-06	29	162	5	IPR002017
Domain	SPEC	SPTAN1 SPTBN5 DST SYNE2 MACF1	7.69e-06	32	162	5	SM00150
Domain	Spectrin/alpha-actinin	SPTAN1 SPTBN5 DST SYNE2 MACF1	7.69e-06	32	162	5	IPR018159
Domain	-	EPPK1 DST MACF1	1.26e-05	6	162	3	3.90.1290.10
Domain	CH	SPTBN5 DST CLMN SYNE2 MACF1 CNN1	2.10e-05	65	162	6	SM00033
Domain	Plectin	EPPK1 DST MACF1	2.19e-05	7	162	3	PF00681
Domain	Plectin_repeat	EPPK1 DST MACF1	2.19e-05	7	162	3	IPR001101
Domain	PLEC	EPPK1 DST MACF1	2.19e-05	7	162	3	SM00250
Domain	Cell_morpho_N	FRYL FRY	7.48e-05	2	162	2	IPR025614
Domain	Cell_Morphogen_C	FRYL FRY	7.48e-05	2	162	2	IPR025481
Domain	MOR2-PAG1_mid	FRYL FRY	7.48e-05	2	162	2	IPR029473
Domain	MOR2-PAG1_mid	FRYL FRY	7.48e-05	2	162	2	PF14228
Domain	MOR2-PAG1_C	FRYL FRY	7.48e-05	2	162	2	PF14225
Domain	MOR2-PAG1_N	FRYL FRY	7.48e-05	2	162	2	PF14222
Domain	WD40_repeat_CS	KIF21B SEC31B WDFY4 NWD2 TLE3 TLE4 HERC1	5.78e-04	164	162	7	IPR019775
Domain	Groucho_enhance	TLE3 TLE4	7.35e-04	5	162	2	IPR009146
Domain	TLE_N	TLE3 TLE4	7.35e-04	5	162	2	PF03920
Domain	Groucho/TLE_N	TLE3 TLE4	7.35e-04	5	162	2	IPR005617
Domain	Pentatricopeptide_repeat	DENND4C GNAS PRORP	9.99e-04	23	162	3	IPR002885
Domain	GAR	DST MACF1	1.10e-03	6	162	2	PS51460
Domain	GAS2	DST MACF1	1.10e-03	6	162	2	PF02187
Domain	-	DST MACF1	1.10e-03	6	162	2	3.30.920.20
Domain	GAS_dom	DST MACF1	1.10e-03	6	162	2	IPR003108
Domain	GAS2	DST MACF1	1.10e-03	6	162	2	SM00243
Domain	LRR_6	KERA FBXL6 NLRP9 TLR4	1.32e-03	55	162	4	PF13516
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TET2 DIP2B RAPGEF6 MAP1B RAPH1 MYO9A IFT74 ARHGEF5 SPTAN1 FRYL BCR DENND4C MTMR4 DST NF1 CLMN RABEP1 PI4KB SYNE2 MACF1 CRYBG3 GNAS PLK4 EDRF1	5.91e-12	861	169	24	36931259
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 USP34 RAPGEF6 RAPH1 IFT74 UBR4 USP24 BCR DENND4C DST RABEP1 TLE3 TLE4 BUB1 CRYBG3	2.42e-09	418	169	15	34709266
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PITPNM2 DIP2B POLR1A MAP1B MYO5A HYKK MYO9A EVC FRYL BTAF1 ARHGAP35 ZNF767P TTC3 BCR ANO8 ZNF331 SMG7 CLMN RABEP1 TLE3 VPS35L CDK5RAP1 MACF1 GNAS PRORP VPS13B NPAS2	3.71e-09	1489	169	27	28611215
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TET2 USP34 MYO5A IFT74 SPTAN1 UBR4 SPOCK2 TTC3 SEC31B ITGB8 ZNF331 UBE4A DGLUCY FRY DST RABEP1 ARIH2 VPS35L MACF1 EXOC7 TARBP1 ECE2 SCAI	7.61e-08	1285	169	23	35914814
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	RAPGEF6 MYO9A DAB2 ARHGAP35 BCR DENND4C DST RABEP1 MACF1 CRYBG3	8.62e-08	209	169	10	36779422
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	MPL DST MACF1	4.49e-07	4	169	3	8954775
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	A2M DIP2B RAB35 RAPGEF6 MAP1B ARHGEF5 BTAF1 BCR ARHGEF40 DST BUB1 CDK5RAP1 CRYBG3 EXOC7 CMTR2	7.54e-07	650	169	15	38777146
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	ROGDI SPTAN1 FRYL COLEC12 DST ARIH2 MACF1 EXOC7	8.10e-07	151	169	8	17043677
Pubmed	Chromosomal localization of mouse bullous pemphigoid antigens. BPAG1 and BPAG2: identification of a new region of homology between mouse and human chromosomes.	FAS DST CTLA4	3.89e-06	7	169	3	8432531
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DIP2B UBR4 FRYL MTMR4 NWD2 SYNE2	4.39e-06	87	169	6	12465718
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	GPI USP34 DYNC2H1 RNF8 SPG11 BTAF1 FAS ZFPL1 QSOX1 DGLUCY NF1 CELSR2 SLC22A5 MACF1 HERC1 ALG6 SCAI IPO11	4.62e-06	1061	169	18	33845483
Pubmed	The branchial Hox code and its implications for gene regulation, patterning of the nervous system and head evolution.	HOXA1 HOXB9 HOXD1	6.20e-06	8	169	3	1688181
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	USP34 EP400 MYO9A DYNC2H1 IFT74 RNF8 BCR SMG7 RABEP1 BUB1 MACF1 CRYBG3 GNAS	6.71e-06	588	169	13	38580884
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PITPNM2 USP34 RAPGEF6 EPPK1 EP400 UBR4 IRF5 FRYL BTAF1 ARHGAP35 TTC3 BCR ANO8 ARHGEF40 DST CELSR2 AKT2 HERC1	8.04e-06	1105	169	18	35748872
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP34 CCDC22 IFT74 USP24 FRYL USP6 NF1	8.12e-06	147	169	7	29576527
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	DIP2B RAPGEF6 ANPEP RAPH1 MYO5A MYO9A IFT74 NOXA1 DAB2 ZNF767P TTC3 FBXL6 USP6 PI4KB TLE3 EXOC7	1.27e-05	925	169	16	28986522
Pubmed	The chromosomal mapping of four genes encoding winged helix proteins expressed early in mouse development.	MPL MYO5A FOXC1	1.32e-05	10	169	3	8661058
Pubmed	DNA-binding specificities of human transcription factors.	TBX21 IRF5 HOXA1 FOXG1	1.53e-05	31	169	4	23332764
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	POLR1A DYNC2H1 IFT74 UBR4 USP24 BTAF1 NCSTN FAS ZFPL1 ARHGEF40 RABEP1 EXOC7 COG5 POMK TARBP1 IPO11	1.58e-05	942	169	16	31073040
Pubmed	Genotyping new BXD recombinant inbred mouse strains and comparison of BXD and consensus maps.	GPI MYO5A CES1	1.81e-05	11	169	3	10087289
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	LETM2 RAB35 EPPK1 POLR1A IFT74 SPTAN1 BMF SPOCK2 TTC3 ZNF331 DST NF1 TLE3 BUB1 VPS35L ANKRD30A PRORP PLK4 HYDIN	1.88e-05	1293	169	19	15342556
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 EPPK1 POLR1A MAP1B MYO5A SPTAN1 UBR4 USP24 FRYL DST NF1 SYNE2 MACF1	2.03e-05	653	169	13	22586326
Pubmed	Interleukin-6 alters the cellular responsiveness to clopidogrel, irinotecan, and oseltamivir by suppressing the expression of carboxylesterases HCE1 and HCE2.	CES1 CES2	2.35e-05	2	169	2	17537833
Pubmed	Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin.	CES1 CES2	2.35e-05	2	169	2	18983829
Pubmed	Human endothelin converting enzyme-2 (ECE2): characterization of mRNA species and chromosomal localization.	EEF1AKMT4-ECE2 ECE2	2.35e-05	2	169	2	11718899
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	2.35e-05	2	169	2	11002341
Pubmed	The pathophysiology and morphology of murine hydrocephalus in Hy-3 and Ch mutants.	HYDIN FOXC1	2.35e-05	2	169	2	4784576
Pubmed	Structural organization and characterization of the regulatory element of the human carboxylesterase (CES1A1 and CES1A2) genes.	CES1 CES2	2.35e-05	2	169	2	18305377
Pubmed	IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation.	IRF5 AKT2	2.35e-05	2	169	2	27545875
Pubmed	Disabled-2 is a negative immune regulator of lipopolysaccharide-stimulated Toll-like receptor 4 internalization and signaling.	DAB2 TLR4	2.35e-05	2	169	2	27748405
Pubmed	TLR4 signal transduction pathways neutralize the effect of Fas signals on glioblastoma cell proliferation and migration.	FAS TLR4	2.35e-05	2	169	2	21852034
Pubmed	Brief report: increased expression of a short splice variant of CTLA-4 exacerbates lupus in MRL/lpr mice.	FAS CTLA4	2.35e-05	2	169	2	23203389
Pubmed	Analysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas.	FAS CTLA4	2.35e-05	2	169	2	19669200
Pubmed	TLE3 and TLE4-coordinated colonic macrophage-CD4+ T cell crosstalk maintains intestinal immune homeostasis.	TLE3 TLE4	2.35e-05	2	169	2	36801171
Pubmed	Identification of carboxylesterase-dependent dabigatran etexilate hydrolysis.	CES1 CES2	2.35e-05	2	169	2	24212379
Pubmed	CD13 restricts TLR4 endocytic signal transduction in inflammation.	ANPEP TLR4	2.35e-05	2	169	2	25801433
Pubmed	Multifaceted contribution of the TLR4-activated IRF5 transcription factor in systemic sclerosis.	IRF5 TLR4	2.35e-05	2	169	2	26598674
Pubmed	Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways.	TLR4 AKT2	2.35e-05	2	169	2	37567009
Pubmed	Examination of the carboxylesterase phenotype in human liver.	CES1 CES2	2.35e-05	2	169	2	22525521
Pubmed	Age- and sex-related expression and activity of carboxylesterase 1 and 2 in mouse and human liver.	CES1 CES2	2.35e-05	2	169	2	19487248
Pubmed	Gro/TLE enables embryonic stem cell differentiation by repressing pluripotent gene expression.	TLE3 TLE4	2.35e-05	2	169	2	25446531
Pubmed	Microtubule stability, Golgi organization, and transport flux require dystonin-a2-MAP1B interaction.	MAP1B DST	2.35e-05	2	169	2	22412020
Pubmed	Predominant contributions of carboxylesterase 1 and 2 in hydrolysis of anordrin in humans.	CES1 CES2	2.35e-05	2	169	2	28532270
Pubmed	Different inhibitory effects in rat and human carboxylesterases.	CES1 CES2	2.35e-05	2	169	2	19225040
Pubmed	Diminished myelin-specific T cell activation associated with increase in CTLA4 and Fas molecules in multiple sclerosis patients treated with IFN-beta.	FAS CTLA4	2.35e-05	2	169	2	17970696
Pubmed	Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin.	CES1 CES2	2.35e-05	2	169	2	20649590
Pubmed	COLEC12 regulates apoptosis of osteosarcoma through Toll-like receptor 4-activated inflammation.	COLEC12 TLR4	2.35e-05	2	169	2	32822099
Pubmed	Inhibition of IRF5 hyperactivation protects from lupus onset and severity.	IRF5 FAS	2.35e-05	2	169	2	32897883
Pubmed	Carboxylesterase in the liver and small intestine of experimental animals and human.	CES1 CES2	2.35e-05	2	169	2	17764701
Pubmed	MiR-196a promotes the proliferation and migration of esophageal cancer via the UHRF2/TET2 axis.	TET2 UHRF2	2.35e-05	2	169	2	34826027
Pubmed	Determination and analysis of single nucleotide polymorphisms and haplotype structure of the human carboxylesterase 2 gene.	CES1 CES2	2.35e-05	2	169	2	15475733
Pubmed	Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny.	CES1 CES2	2.35e-05	2	169	2	26825642
Pubmed	Pharmacogenomic assessment of carboxylesterases 1 and 2.	CES1 CES2	2.35e-05	2	169	2	15475243
Pubmed	Mutual regulation between GDF11 and TET2 prevents senescence of mesenchymal stem cells.	TET2 GDF11	2.35e-05	2	169	2	37801347
Pubmed	Rab35 Functions in Axon Elongation Are Regulated by P53-Related Protein Kinase in a Mechanism That Involves Rab35 Protein Degradation and the Microtubule-Associated Protein 1B.	RAB35 MAP1B	2.35e-05	2	169	2	27383602
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	USP34 MYO9A DYNC2H1 UBR4 DST SYNE2 MACF1 GNAS ECE2	3.05e-05	322	169	9	26514267
Pubmed	Complete mutation analysis panel of the 39 human HOX genes.	HOXA1 HOXB9 HOXC12 HOXD1	3.49e-05	38	169	4	11857506
Pubmed	Atlas of Hox gene expression in the developing kidney.	HOXA1 HOXB9 HOXC12 HOXD1	3.49e-05	38	169	4	15042701
Pubmed	Functional proteomics mapping of a human signaling pathway.	A2M ZMYND11 ERCC6 UBR4 DAB2 TTC3 MTMR4 DST MACF1 NIT1 HERC1 UHRF2	3.52e-05	591	169	12	15231748
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	ZMYND11 MAP1B UBR4 NCSTN ARHGAP35 ZC3H6 QSOX1 COLEC12 SMG7 CLMN PRORP TARBP1 IPO11	3.53e-05	689	169	13	36543142
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	KIF21B DNAH10 DYNC2H1 SPTAN1 SPTBN5 DST SYNE2	3.84e-05	187	169	7	26460568
Pubmed	Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster.	HOXA1 HOXB9 HOXC12 HOXD1	3.88e-05	39	169	4	33257809
Pubmed	Quantification of Hox and surfactant protein-B transcription during murine lung development.	HOXA1 HOXB9 HOXC12 HOXD1	4.29e-05	40	169	4	19204410
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	PITPNM2 RAB35 MAP1B MYO5A SPTAN1 UBR4 USP24 CPZ ARHGAP35 BCR ANO8 NF1 CELSR2 RABEP1 MACF1 AKT2 CRYBG3	4.36e-05	1139	169	17	36417873
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	ERCC6 MAP1B SPTAN1 COX10 ARHGAP35 FAM186B QSOX1 DST SLC22A5 ADAMTS20 BMP15	4.60e-05	513	169	11	25798074
Pubmed	Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates.	HOXA1 HOXB9 HOXC12 HOXD1	4.74e-05	41	169	4	32479258
Pubmed	Reduction of Hox gene expression by histone H1 depletion.	HOXA1 HOXB9 HOXC12 HOXD1	5.73e-05	43	169	4	22701719
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PITPNM2 KIF21B TET2 USP34 EP400 SPG11 NCSTN BCR DST SMG7 CEP126	6.06e-05	529	169	11	14621295
Pubmed	Nomenclature for human homeobox genes.	HOXA1 HOXB9 HOXC12 HOXD1	6.28e-05	44	169	4	1973146
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	EPPK1 ERCC6 MAP1B DYNC2H1 CELSR2 SYNE2 MACF1 GDF11 FOXC1	6.91e-05	358	169	9	32460013
Pubmed	Human carboxylesterases: an update on CES1, CES2 and CES3.	CES1 CES2	7.02e-05	3	169	2	19508181
Pubmed	A novel GIP receptor splice variant influences GIP sensitivity of pancreatic beta-cells in obese mice.	GIP GNAS	7.02e-05	3	169	2	17971513
Pubmed	Human carboxylesterases in term placentae: enzymatic characterization, molecular cloning and evidence for the existence of multiple forms.	CES1 CES2	7.02e-05	3	169	2	10452915
Pubmed	Myosin 5a is an insulin-stimulated Akt2 (protein kinase Bbeta) substrate modulating GLUT4 vesicle translocation.	MYO5A AKT2	7.02e-05	3	169	2	17515613
Pubmed	Roles of endotoxin-related signaling molecules in the progression of acute necrotizing pancreatitis in mice.	LBP TLR4	7.02e-05	3	169	2	16163057
Pubmed	Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus.	TET2 FAS	7.02e-05	3	169	2	35499082
Pubmed	A transgenic insertional inner ear mutation on mouse chromosome 1.	DST CTLA4	7.02e-05	3	169	2	10763993
Pubmed	Polymorphisms and haplotypes of TLR4, TLR9 and CYP1A1 genes possibly interfere with high-risk human papillomavirus infection and cervical cancer susceptibility in Jharkhand, India.	CYP1A1 TLR4	7.02e-05	3	169	2	32871478
Pubmed	Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation.	SPG11 PI4KB	7.02e-05	3	169	2	25365221
Pubmed	Tyrosine kinase 2 and interferon regulatory factor 5 polymorphisms are associated with discoid and subacute cutaneous lupus erythematosus.	IRF5 CTLA4	7.02e-05	3	169	2	19758313
Pubmed	Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation.	FAS TLR4	7.02e-05	3	169	2	15004557
Pubmed	Altered HOX and WNT7A expression in human lung cancer.	HOXA1 HOXB9	7.02e-05	3	169	2	11070089
Pubmed	[Expressions of Fas, CTLA-4 and RhoBTB2 genes in breast carcinoma and their relationship with clinicopathological factors].	FAS CTLA4	7.02e-05	3	169	2	19173804
Pubmed	Association of the blood serum cytokines' rate and lymphocytes' apoptosis with polymorphic variants of the BCL-2 (rs17759659), CTLA-4 (rs231775) and APO-1÷FAS (rs2234767) genes in patients with nodular goiters in autoimmune thyroiditis and thyroid adenoma.	FAS CTLA4	7.02e-05	3	169	2	29250672
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	7.02e-05	3	169	2	12399109
Pubmed	Toll-like receptor 2 or toll-like receptor 4 deficiency does not modify lupus in MRLlpr mice.	FAS TLR4	7.02e-05	3	169	2	24086313
Pubmed	The association between Cytotoxic T lymphocyte associated antigen-4, Fas, tumour necrosis factor-α gene polymorphisms and autoimmune hepatitis: a meta-analysis.	FAS CTLA4	7.02e-05	3	169	2	24629822
Pubmed	TP53 Mutation as Potential Negative Predictor for Response of Anti-CTLA-4 Therapy in Metastatic Melanoma.	FAS CTLA4	7.02e-05	3	169	2	29793878
Pubmed	Akt recruits Dab2 to albumin endocytosis in the proximal tubule.	DAB2 AKT2	7.02e-05	3	169	2	25253241
Pubmed	[IL1/IL1 Ra, CTLA-4 and Apo1/Fas genes polymorphisms and susceptibility to IgA nephropathy in Tunisian patients].	FAS CTLA4	7.02e-05	3	169	2	21049406
Pubmed	The effect of the accessory proteins, soluble CD14 and lipopolysaccharide-binding protein on Toll-like receptor 4 activity in human monocytes and adipocytes.	LBP TLR4	7.02e-05	3	169	2	26880233
Pubmed	Genetic variation of an intestinal leucine arylaminopeptidase (Lap-1) in the mouse and its location on chromosome 9.	ANPEP MYO5A	7.02e-05	3	169	2	1203051
Pubmed	Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2.	IRF5 FAS	7.02e-05	3	169	2	25076492
Pubmed	Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity.	TLE3 TLE4	7.02e-05	3	169	2	30045946
Pubmed	Fas-Fas ligand (CD95-CD95L) and cytotoxic T lymphocyte antigen-4 engagement mediate T cell unresponsiveness in patients with paracoccidioidomycosis.	FAS CTLA4	7.02e-05	3	169	2	12717632
Pubmed	MAP1B and clathrin are novel interacting partners of the giant cyto-linker dystonin.	MAP1B DST	7.02e-05	3	169	2	21936565
Pubmed	Genetic variation in carboxylesterase genes and susceptibility to isoniazid-induced hepatotoxicity.	CES1 CES2	7.02e-05	3	169	2	20195289
Pubmed	Critical role of TLR2 and TLR4 in autoantibody production and glomerulonephritis in lpr mutation-induced mouse lupus.	FAS TLR4	7.02e-05	3	169	2	19841185
Pubmed	Polymorphsims of CTLA-4 exon 1 +49, CTLA-4 promoter -318 and Fas promoter -670 in spondyloarthropathies.	FAS CTLA4	7.02e-05	3	169	2	11771526
Pubmed	T-bet is a new synergistic meeting point for the BCR and TLR9 signaling cascades.	TBX21 BCR	7.02e-05	3	169	2	24249581
Interaction	GOLGA1 interactions	RAPGEF6 IFT74 UBR4 USP24 ARHGAP35 DENND4C DST SMG7 CLMN MACF1 CRYBG3	3.15e-07	183	164	11	int:GOLGA1
Interaction	C3orf18 interactions	DYNC2H1 USP24 BTAF1 UBE4A NF1 PRORP EXOC7 TARBP1 IPO11	4.23e-07	115	164	9	int:C3orf18
Interaction	KDM1A interactions	TET2 USP34 CCDC121 RAPGEF6 EP400 RAPH1 IFT74 UBR4 USP24 BCR DENND4C HOXA1 DST SMG7 RABEP1 TLE3 TLE4 BUB1 CRYBG3 EXOC7 FOXG1 ECE2 FOXC1	2.40e-06	941	164	23	int:KDM1A
Interaction	YWHAH interactions	KIF21B TET2 DIP2B RAPGEF6 EPPK1 MYO9A IFT74 ARHGEF5 SPTAN1 FRYL BCR DENND4C MTMR4 DST NF1 CLMN RABEP1 PI4KB SYNE2 MACF1 CRYBG3 HERC1 PLK4 EDRF1	1.01e-05	1102	164	24	int:YWHAH
Interaction	PDZK1 interactions	FRYL BCR CRHR1 COLEC12 SLC22A5 CDK5RAP1	1.61e-05	66	164	6	int:PDZK1
Interaction	PFN1 interactions	RAPGEF6 RAPH1 MYO5A MYO9A IFT74 SPTAN1 ARHGAP35 BCR DENND4C NF1 SMG7 RABEP1 SYNE2 MACF1 CRYBG3	1.85e-05	509	164	15	int:PFN1
Interaction	GSK3A interactions	RAPGEF6 MYO9A DAB2 CPZ ARHGAP35 BCR ZC3H6 DENND4C DST SMG7 RABEP1 MACF1 AKT2 CRYBG3	2.75e-05	464	164	14	int:GSK3A
Interaction	HDAC1 interactions	TET2 ZMYND11 RAPGEF6 ERCC6 EP400 RAPH1 IFT74 SPTAN1 UBR4 USP24 IRF5 BCR DENND4C DST RABEP1 TLE3 TLE4 SYNE2 BUB1 CRYBG3 UHRF2 POMK FOXG1	3.35e-05	1108	164	23	int:HDAC1
Interaction	SFN interactions	TET2 RAPGEF6 MAP1B MYO9A ARHGEF5 SPTAN1 RNF8 FRYL BCR DENND4C MTMR4 DST CLMN PI4KB MACF1 CRYBG3 PLK4	5.14e-05	692	164	17	int:SFN
Interaction	RCOR1 interactions	USP34 RAPGEF6 RAPH1 IFT74 SPTAN1 UBR4 USP24 BCR DENND4C DST RABEP1 BUB1 UHRF2 ECE2	5.43e-05	494	164	14	int:RCOR1
Cytoband	16q22.2	CES1 CMTR2 HYDIN	7.17e-05	22	169	3	16q22.2
GeneFamily	EF-hand domain containing\|Plakins	EPPK1 DST MACF1	1.17e-05	8	109	3	939
GeneFamily	HOXL subclass homeoboxes	HOXA1 HOXB9 HOXC12 HOXD1	2.71e-04	52	109	4	518
GeneFamily	Carboxylesterases	CES1 CES2	3.56e-04	5	109	2	461
GeneFamily	EF-hand domain containing\|Spectrins	SPTAN1 SPTBN5	7.42e-04	7	109	2	1113
GeneFamily	WD repeat domain containing	KIF21B FBXW12 SEC31B WDFY4 TLE3 TLE4 HERC1	1.05e-03	262	109	7	362
Coexpression	GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_UP	USP34 DIP2B RAPGEF6 UBR4 TBX21 USP24 TTC3 CRHR1 TLE4 HERC1 EDRF1	7.83e-08	200	169	11	M387
Coexpression	POOLA_INVASIVE_BREAST_CANCER_DN	CYP1A1 ANPEP ARHGEF5 DST CELSR2 CLMN RABEP1 EXOC7 CNN1	2.14e-07	133	169	9	M6767
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	USP34 ZMYND11 MAP1B USP24 SPG11 FRYL BTAF1 ARHGAP35 TDRD7 USP6 DST TLE4 SYNE2 MACF1 CRYBG3 BCAR3 COG5 VPS13B	1.14e-05	856	169	18	M4500
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	KIF21B TET2 USP24 FRYL NF1 CELSR2 MACF1 HERC1	2.31e-05	180	169	8	M8239
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	USP24 FRYL USP6 DST TLE4 BCAR3 PLK4 EDRF1 VPS13B NPAS2	2.68e-05	300	169	10	M8702
Coexpression	GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_BCELL_DN	ARHGEF5 ARHGAP35 ZNF767P CES2 HOXA1 BCAR3 PLK4 GGPS1	4.23e-05	196	169	8	M4990
Coexpression	DAZARD_UV_RESPONSE_CLUSTER_G6	USP24 FRYL USP6 TLE4 EDRF1 VPS13B NPAS2	4.48e-05	145	169	7	M1810
Coexpression	GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN	TET2 EPPK1 TBX21 GARS1 USP24 FAS ZFPL1 TLE3	4.88e-05	200	169	8	M3659
Coexpression	KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN	A2M SPTAN1 DAB2 QSOX1 COLEC12 DST HMCN1 CRYBG3 GNAS FOXC1	7.10e-05	337	169	10	M13206
Coexpression	MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN	EP400 FRYL BTAF1 MTMR4 BUB1 VPS35L GGPS1 TARBP1 NPAS2	7.20e-05	272	169	9	M15123
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	A2M USP24 FRYL BTAF1 SEC31B ITGB8 SYNE2 MACF1 HERC1 VPS13B	3.49e-09	193	168	10	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 USP24 FRYL BTAF1 SEC31B SYNE2 MACF1 HERC1 UHRF2	6.39e-08	197	168	9	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	A2M USP34 USP24 FRYL BTAF1 SYNE2 MACF1 HERC1 VPS13B	6.97e-08	199	168	9	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / Treatment groups by lineage, cell group, cell type	MAP1B SPTAN1 SPOCK2 BCR FRY DST HMCN1 SYNE2 GNAS	7.27e-08	200	168	9	b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL32 SPOCK2 FAS NF1 SYNE2 BUB1 CTLA4 FOXC1	3.06e-07	172	168	8	eee45759284baa3ed77da6a5fbcc4f8f6c553106
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFAP47 CCDC121 DNAH10 RGS22 MYCBPAP CFAP77 TAS1R2 HYDIN	3.81e-07	177	168	8	3cfde67b93f3986312f5e74e42504214d966e7dc
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFAP47 CCDC121 DNAH10 RGS22 MYCBPAP CFAP77 TAS1R2 HYDIN	3.81e-07	177	168	8	12a52a12a87a31e501ced611f46a90d172ca7e35
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 DYNC2H1 RGS22 HOXD1 CFAP77 CEP126 HYDIN	7.34e-07	193	168	8	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 DYNC2H1 RGS22 MYCBPAP SYNE2 CEP126 HYDIN	8.56e-07	197	168	8	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	COVID-19_Mild-Classical_Monocyte\|COVID-19_Mild / Disease condition and Cell class	ANPEP CES1 IFNGR2 QSOX1 ARHGEF40 CLMN TLE3 TLR4	8.89e-07	198	168	8	30ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PITPNM2 SPTAN1 MYCBPAP FRY DST TLE4 SYNE2 MACF1	9.59e-07	200	168	8	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	MAP1B MYO5A TTC3 FRY DST NF1 SYNE2 FOXG1	9.59e-07	200	168	8	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	COVID-Treg\|COVID / Condition, Cell_class and T cell subcluster	IL32 ARHGEF5 SPTAN1 SPOCK2 SYNE2 CTLA4 PRORP	2.18e-06	156	168	7	a1dd61d4c9ed8f283f0fcbf875c5fd7807ca370d
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EPPK1 DNAH10 CES1 DYNC2H1 CES2 CEP126 HYDIN	5.61e-06	180	168	7	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC121 EPPK1 RGS22 LBP MYCBPAP CFAP77 HYDIN	6.03e-06	182	168	7	587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCell	Control-Lymphoid-T_Regulatory\|Control / Disease state, Lineage and Cell class	IL32 RAPGEF6 SPOCK2 FAS SYNE2 CTLA4 UHRF2	6.03e-06	182	168	7	31bb838cc2900f3c9da9f835d79d557a08abb928
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC121 EPPK1 RGS22 LBP MYCBPAP CFAP77 HYDIN	6.03e-06	182	168	7	adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A EVC SPOCK2 ITGB8 AKT2 HYDIN FOXC1	6.25e-06	183	168	7	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M DNAH10 RGS22 HMCN1 ADAMTS20 MYO15A HYDIN	6.47e-06	184	168	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 DNAH10 LBP MYCBPAP CFAP77 BBS12 HYDIN	6.47e-06	184	168	7	264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M DNAH10 RGS22 HMCN1 ADAMTS20 MYO15A HYDIN	6.47e-06	184	168	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M DNAH10 RGS22 HMCN1 ADAMTS20 MYO15A HYDIN	6.47e-06	184	168	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 DNAH10 LBP MYCBPAP CFAP77 BBS12 HYDIN	6.47e-06	184	168	7	d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 DNAH10 LBP MYCBPAP CFAP77 BBS12 HYDIN	6.47e-06	184	168	7	22010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCell	COPD-Lymphoid-T_Regulatory\|COPD / Disease state, Lineage and Cell class	IL32 RAPGEF6 SPOCK2 FAS SYNE2 CTLA4 UHRF2	6.71e-06	185	168	7	846403edd4c8f646201d519055198fc38b7ffff9
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 DNAH10 MAP1B DYNC2H1 RGS22 MYCBPAP HYDIN	6.71e-06	185	168	7	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL32 TBX21 SPOCK2 SYNE2 BUB1 CTLA4 UHRF2	6.71e-06	185	168	7	f1263899a2d41d182022dc4ca62cbae08a463c89
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	A2M IL32 TBX21 C1orf167 FRY PRORP FOXC1	6.95e-06	186	168	7	055cc23c4db9aad2d6c62e62c8e58bfe5047c6b1
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	7.20e-06	187	168	7	e61992de4f98eeea08b43213850769d923f8db48
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 USP24 BTAF1 NF1 SYNE2 MACF1 HERC1	7.45e-06	188	168	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	21-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	DNAH10 CES1 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	7.45e-06	188	168	7	803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP47 DNAH10 RGS22 MYCBPAP CFAP77 CEP126 HYDIN	7.71e-06	189	168	7	dc440015949a768188c67661b6be63b1ead1a0f0
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	CFAP47 DNAH10 RGS22 MYCBPAP CFAP77 CEP126 HYDIN	7.71e-06	189	168	7	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP47 DNAH10 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	7.71e-06	189	168	7	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	COPD-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	TET2 RAPGEF6 CCDC22 FAS SYNE2 CTLA4 UHRF2	8.26e-06	191	168	7	3ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M IL32 SPTAN1 SPOCK2 ARHGAP35 SYNE2 CTLA4	8.26e-06	191	168	7	4a29b7d5cd10e9077699d3aa76e3db6c4d5a0cf6
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFAP47 DNAH10 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	8.26e-06	191	168	7	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CES1 EVC CCDC178 CCDC38 ITGB8 MYH16 HYDIN	8.55e-06	192	168	7	d6f656be2698bd215717d35f4e7ab727c08c61e0
ToppCell	IPF-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP47 DNAH10 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	8.55e-06	192	168	7	d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCell	IPF-Epithelial-Ciliated\|IPF / Disease state, Lineage and Cell class	CFAP47 DNAH10 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	8.55e-06	192	168	7	354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP47 DNAH10 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	8.84e-06	193	168	7	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A EVC SPOCK2 ITGB8 SYNE2 HYDIN FOXC1	8.84e-06	193	168	7	ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	USP34 DIP2B FRYL DENND4C CRYBG3 POMK VPS13B	8.84e-06	193	168	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 DNAH10 CES1 DYNC2H1 CLMN CEP126 HYDIN	8.84e-06	193	168	7	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	15-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	DNAH10 CES1 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	8.84e-06	193	168	7	aa3acc7571405169efb656d214f3a8cbf988362e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A EVC SPOCK2 ITGB8 SYNE2 AKT2 FOXC1	8.84e-06	193	168	7	0f2167eef8203a5659c8c72e4e77646003d64797
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP47 DNAH10 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	8.84e-06	193	168	7	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP47 DNAH10 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	9.14e-06	194	168	7	958e648138676d46698090b4046cb484083ae449
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	CFAP47 DNAH10 DYNC2H1 RGS22 SYNE2 CEP126 HYDIN	9.46e-06	195	168	7	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IL32 SPTAN1 SPOCK2 TTC3 SYNE2 MACF1 CTLA4	9.46e-06	195	168	7	4bdedd924564a260841a9153604026b57487c83d
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B DYNC2H1 FRYL TTC3 DST MACF1 HERC1	9.46e-06	195	168	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B DYNC2H1 FRYL TTC3 DST MACF1 HERC1	9.46e-06	195	168	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 CES1 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	9.78e-06	196	168	7	a37ba02446eef5d1fab703204583f6550a8ec3e1
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	A2M CES1 QSOX1 COLEC12 DST HMCN1 MACF1	9.78e-06	196	168	7	6730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell	healthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	A2M IL32 TBX21 SPOCK2 BCR SYNE2 MACF1	9.78e-06	196	168	7	af00c31612e4fe068e5fccae05368edba46bbd20
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 CES1 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	9.78e-06	196	168	7	a156840330630e518bc85633dded6f2c3ead3b30
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	A2M CES1 QSOX1 COLEC12 DST HMCN1 MACF1	9.78e-06	196	168	7	21dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 CES1 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	9.78e-06	196	168	7	89ea4d2086e1c769c5a87f1471a6cd4acabcfe33
ToppCell	Sepsis-URO-Lymphocyte-T/NK-Treg\|URO / Disease, condition lineage and cell class	IL32 PRSS16 SPOCK2 MYCBPAP SYNE2 CTLA4 PLK4	9.78e-06	196	168	7	8812d7365fb2b33feff93782d60776e932499a43
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IL32 SPTAN1 TBX21 SPOCK2 TTC3 SYNE2 MACF1	1.01e-05	197	168	7	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	A2M IL32 TBX21 SPOCK2 SPG11 SYNE2 MACF1	1.01e-05	197	168	7	836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 CES1 DYNC2H1 CLMN CEP126 HYDIN	1.01e-05	197	168	7	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 DNAH10 CES1 DYNC2H1 CLMN CEP126 HYDIN	1.01e-05	197	168	7	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 CES1 DYNC2H1 CLMN CEP126 HYDIN	1.01e-05	197	168	7	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 CES1 DYNC2H1 CLMN CEP126 HYDIN	1.01e-05	197	168	7	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	10x5'-Liver-Lymphocytic_T_CD4\|Liver / Manually curated celltypes from each tissue	IL32 RAPGEF6 SPTAN1 SPOCK2 FAS SYNE2 CTLA4	1.01e-05	197	168	7	4891111894b741555f549deec6af8006376d9358
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 CES1 DYNC2H1 CLMN CEP126 HYDIN	1.01e-05	197	168	7	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	CYP1A1 SPTAN1 SPOCK2 DST HMCN1 MACF1 GNAS	1.08e-05	199	168	7	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	SPTAN1 USP24 SEC31B SMG7 SYNE2 MACF1 CTLA4	1.08e-05	199	168	7	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	1.11e-05	200	168	7	cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PITPNM2 USP34 SPTAN1 DST HMCN1 SYNE2 MACF1	1.11e-05	200	168	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SPTAN1 BCR FRY DST HMCN1 SYNE2 FOXC1	1.11e-05	200	168	7	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	1.11e-05	200	168	7	79e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCell	Biopsy_IPF-Epithelial-Ciliated\|Biopsy_IPF / Sample group, Lineage and Cell type	CFAP47 DNAH10 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	1.11e-05	200	168	7	bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCell	control-gd_T\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	IL32 SPTAN1 TBX21 SPOCK2 ZNF331 SYNE2 GNAS	1.11e-05	200	168	7	b188f2acb9bd4f5f1ad4c3d3ddb9a55854a8b74b
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	1.11e-05	200	168	7	873def69bf55ccbfc944bc10c5afc06be019c312
ToppCell	control-HLA-DR-_S100A+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 ROGDI ANPEP CES1 IRF5 QSOX1 TLR4	1.11e-05	200	168	7	9e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	RAPGEF6 BTAF1 FAM186B SYNE2 MACF1 HERC1	1.25e-05	135	168	6	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	IL32 SPOCK2 FAS ZNF331 TLE4 SYNE2	1.48e-05	139	168	6	2fdc8f36510aff24abbc79ef2a842db75a85f946
ToppCell	343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	IL32 SPOCK2 FAS ZNF331 TLE4 SYNE2	1.48e-05	139	168	6	5970a654c64e3b54f9d18c102f5b125eec892fc5
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	KIF21B CYP1A1 IL32 TBX21 SYNE2 EDRF1	2.03e-05	147	168	6	743767abdb3b5ecad870b617f515b037ce280818
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	PITPNM2 IL32 ARHGEF5 SPOCK2 ZFPL1 CTLA4	2.11e-05	148	168	6	80470353e12599440f711b6e107730763376d04d
ToppCell	COVID-Treg-CD4_Treg\|COVID / Condition, Cell_class and T cell subcluster	IL32 ARHGEF5 SPTAN1 SPOCK2 SYNE2 CTLA4	2.54e-05	153	168	6	47c649fd4231e507f2d4654ccac61faf21a04eff
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KIF21B CYP1A1 CES1 TBX21 TLR4 EDRF1	2.83e-05	156	168	6	c11ca6b1b5029c15aab91273cece70a487287839
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAH10 TBX21 SPOCK2 BUB1 CTLA4 PLK4	3.15e-05	159	168	6	2233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCell	368C-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CCDC121 WDFY4 GALNT16 FBXL6 HOXA1 CTLA4	3.63e-05	163	168	6	299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCell	Ciliated_cells-B-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	CFAP47 DYNC2H1 RGS22 CFAP77 CEP126 HYDIN	3.75e-05	164	168	6	fd30c55d0d75ef8b9396435d836187168095152b
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IL32 SPTAN1 SPOCK2 FAS SYNE2 CTLA4	3.88e-05	165	168	6	dbe231d00843cae917efd1abea6079ace3b45cdf
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IL32 SPTAN1 SPOCK2 FAS SYNE2 CTLA4	3.88e-05	165	168	6	9ccce713d4122054bf4bef4a7126d90cf9141b84
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-Tregs\|bone_marrow / Manually curated celltypes from each tissue	IL32 RAPGEF6 SPOCK2 FAS SYNE2 CTLA4	3.88e-05	165	168	6	1ae1ad4e1fe19b6eefff0f9a03d58a384f169759
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 MAP1B DYNC2H1 RGS22 CEP126 HYDIN	4.44e-05	169	168	6	8bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 DYNC2H1 MYCBPAP CEP126 HYDIN	4.44e-05	169	168	6	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL32 FAS ZFPL1 MTMR4 CDK5RAP1 CNN1	4.44e-05	169	168	6	01a24a8817628125bd004b2be68ffa62c7111f6e
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	MPL CFAP47 RGS22 MYCBPAP WDFY4 COLEC12	4.74e-05	171	168	6	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RAPGEF6 BTAF1 ZNF331 SYNE2 MACF1 HERC1	4.74e-05	171	168	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	IL32 SPOCK2 FAM186B NLRP9 SYNE2 CTLA4	4.89e-05	172	168	6	9497948bbe53fb88c6ff6b347f743d456da587e5
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TET2 MYO5A MYO9A DAB2 DST MACF1	5.05e-05	173	168	6	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TET2 MYO5A MYO9A DAB2 DST MACF1	5.05e-05	173	168	6	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TET2 MYO5A MYO9A DAB2 DST MACF1	5.05e-05	173	168	6	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CFAP47 EPPK1 DNAH10 RGS22 MYCBPAP CFAP77	5.39e-05	175	168	6	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
Drug	Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A	USP34 RAB35 IFT74 ARHGAP35 FAS NF1 SMG7 RABEP1 MACF1 EXOC7 EDRF1 VPS13B	2.42e-08	196	167	12	5425_DN
Drug	Repaglinide [135062-02-1]; Down 200; 8.8uM; PC3; HT_HG-U133A	CCDC22 EP400 PRSS16 TDRD7 SMG7 TLE3 TLE4 ARIH2 EXOC7 NPAS2	2.34e-06	200	167	10	5862_DN
Drug	Carbarsone [121-59-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A	A2M LBP FAS ZFPL1 HOXD1 EXOC7 FOXG1 EDRF1 VPS13B	1.33e-05	193	167	9	3250_UP
Drug	aspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A	RAB35 DYNC2H1 IFT74 FAS CES2 SMG7 TLE4 BUB1 EXOC7	1.33e-05	193	167	9	6964_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	RAB35 FAS CES2 ZNF331 SMG7 CLMN RABEP1 TLE3 EXOC7	1.44e-05	195	167	9	6966_DN
Drug	Etomidate [33125-97-2]; Up 200; 16.4uM; HL60; HT_HG-U133A	SPTAN1 UBR4 DAB2 BCR ZFPL1 SMG7 ARIH2 AKT2 EXOC7	1.50e-05	196	167	9	2958_UP
Drug	Trimetazidine dihydrochloride [13171-25-0]; Down 200; 11.8uM; PC3; HT_HG-U133A	IRF5 BCR HOXB9 NF1 RABEP1 ARIH2 PLK4 CNN1 FOXG1	1.50e-05	196	167	9	5060_DN
Drug	Bufexamac [2438-72-4]; Down 200; 18uM; MCF7; HT_HG-U133A	CYP1A1 CCDC22 IRF5 ARHGAP35 NF1 SMG7 TLE3 BUB1 BCAR3	1.63e-05	198	167	9	5515_DN
Drug	Sulfadoxine [2447-57-6]; Down 200; 12.8uM; MCF7; HT_HG-U133A	RAB35 USP24 ZFPL1 SMG7 TLE3 TLE4 ARIH2 FOXG1 EDRF1	1.69e-05	199	167	9	7205_DN
Drug	geldanamycin	TET2 CYP1A1 ZMYND11 MAP1B MYO5A FRYL TTC3 DST NF1 RABEP1 TLE4 TLR4	2.00e-05	371	167	12	ctd:C001277
Drug	4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide	CYP1A1 CES1 CES2	2.11e-05	8	167	3	ctd:C082137
Drug	plakin	SPTAN1 SPTBN5 DST SYNE2 MACF1 GNAS	3.14e-05	82	167	6	CID000018752
Drug	5-iodoisatin	CES1 CES2	5.35e-05	2	167	2	CID000088695
Drug	5-chloro-7-methylisatin	CES1 CES2	5.35e-05	2	167	2	CID000366710
Drug	I08-742	CES1 CES2	5.35e-05	2	167	2	CID002786143
Drug	3,3'-dimethoxybenzil	CES1 CES2	5.35e-05	2	167	2	CID000123493
Drug	tolserine	CES1 CES2	5.35e-05	2	167	2	ctd:C412047
Drug	NSC-379518	CES1 CES2	5.35e-05	2	167	2	CID000137905
Drug	aceanthrenequinone	CES1 CES2	5.35e-05	2	167	2	CID000316765
Drug	7-trifluoromethylisatin	CES1 CES2	5.35e-05	2	167	2	CID000604575
Drug	5-chloroisatin	CES1 CES2	5.35e-05	2	167	2	CID000087203
Drug	4-Chlorobenzil	CES1 CES2	5.35e-05	2	167	2	CID000089801
Drug	4,5-dichloro-1H-indole-2,3-dione	CES1 CES2	5.35e-05	2	167	2	CID005139980
Drug	p-methylbenzil	CES1 CES2	5.35e-05	2	167	2	CID000075511
Drug	AC1Q27R1	CES1 CES2	5.35e-05	2	167	2	CID000087502
Drug	AC1M2MWF	CES1 CES2	5.35e-05	2	167	2	CID002147394
Drug	d18-75	CES1 CES2	5.35e-05	2	167	2	CID000076996
Drug	NSC 408976	CES1 CES2	5.35e-05	2	167	2	CID000101375
Drug	2,2'-Dichlorobenzil	CES1 CES2	5.35e-05	2	167	2	CID000089076
Drug	6-chloro-7-methyl-1H-indole-2,3-dione	CES1 CES2	5.35e-05	2	167	2	CID004513067
Drug	5,7-dichloroisatin	CES1 CES2	5.35e-05	2	167	2	CID000080771
Drug	p-methoxybenzil	CES1 CES2	5.35e-05	2	167	2	CID000031494
Drug	AC1N9FPX	CES1 CES2	5.35e-05	2	167	2	CID004384851
Drug	4-nitrobenzil	CES1 CES2	5.35e-05	2	167	2	CID000283893
Drug	chloroisatin	CES1 CES2	5.35e-05	2	167	2	CID000137777
Drug	4-chloro-7-methyl-1h-indole-2,3-dione	CES1 CES2	5.35e-05	2	167	2	CID001810509
Drug	acetaldophosphamide	CES1 CES2	5.35e-05	2	167	2	CID000163905
Drug	4,4'-Difluorobenzil	CES1 CES2	5.35e-05	2	167	2	CID000123072
Drug	4,4'-Dichlorobenzil	CES1 CES2	5.35e-05	2	167	2	CID000018946
Drug	1-laurylisatin	CES1 CES2	5.35e-05	2	167	2	CID001897797
Drug	1-cetylisatin	CES1 CES2	5.35e-05	2	167	2	CID003772674
Drug	AC1M5V1J	CES1 CES2	5.35e-05	2	167	2	CID002385967
Drug	DNC005462	CES1 CES2	5.35e-05	2	167	2	CID011437501
Drug	2-nitrophenylacetic acid	CES1 CES2	5.35e-05	2	167	2	ctd:C119971
Drug	DNC005463	CES1 CES2	5.35e-05	2	167	2	CID011392969
Drug	AC1MS20N	CES1 CES2	5.35e-05	2	167	2	CID003527426
Drug	9-amino-6-chloro-2-methoxyacridine	CES1 CES2	5.35e-05	2	167	2	ctd:C010847
Drug	1,2-bis(4-nitrophenyl)ethane-1,2-dione	CES1 CES2	5.35e-05	2	167	2	CID001812008
Drug	4-amino-2,6-dimethylphenol	CES1 CES2	5.35e-05	2	167	2	CID000082667
Drug	2-chloro-3',4'-dimeth-oxy-benzil	CES1 CES2	5.35e-05	2	167	2	CID000092036
Drug	4,7-dichloroisatin	CES1 CES2	5.35e-05	2	167	2	CID002734793
Drug	4,6-dichloro-1h-indole-2,3-dione	CES1 CES2	5.35e-05	2	167	2	CID000251908
Drug	AC1LWPKX	CES1 CES2	5.35e-05	2	167	2	CID001755771
Drug	AC1Q2DS8	CES1 CES2	5.35e-05	2	167	2	CID002427416
Drug	1,2-dicyclohexylethane-1,2-dione	CES1 CES2	5.35e-05	2	167	2	CID011806279
Drug	DP00565	CES1 CES2	5.35e-05	2	167	2	CID002777298
Drug	diethyl fluoromalonate	CES1 CES2	5.35e-05	2	167	2	CID000012702
Drug	anisil	CES1 CES2	5.35e-05	2	167	2	CID000071043
Drug	4-chloroisatin	CES1 CES2	5.35e-05	2	167	2	CID000096047
Drug	6-O-monoacetylmorphine	CES1 CES2	5.35e-05	2	167	2	ctd:C026979
Drug	NNMP	CES1 CES2	5.35e-05	2	167	2	CID000146767
Drug	aniracetam	CES1 CES2	5.35e-05	2	167	2	ctd:C036466
Drug	AC1Q24Z2	CES1 CES2	5.35e-05	2	167	2	CID004338240
Drug	1-benzyl-1h-indole-2,3-dione	CES1 CES2	5.35e-05	2	167	2	CID000264734
Drug	prolyl-beta-naphthylamide	CES1 CES2	5.35e-05	2	167	2	CID000167505
Drug	5-(Trifluoro-meth-oxy)isatin	CES1 CES2	5.35e-05	2	167	2	CID002732752
Drug	hostacain	CES1 CES2	5.35e-05	2	167	2	CID000022378
Drug	phenethylcymserine	CES1 CES2	5.35e-05	2	167	2	ctd:C576198
Drug	5,6-dichloro-1H-indole-2,3-dione	CES1 CES2	5.35e-05	2	167	2	CID011009341
Drug	4-nitrophenylacetic acid	CES1 CES2	5.35e-05	2	167	2	ctd:C118008
Drug	AC1MBV04	CES1 CES2	5.35e-05	2	167	2	CID002731732
Drug	AC1N4VNK	CES1 CES2	5.35e-05	2	167	2	CID004135273
Drug	dimethyl adipimidate	ANPEP SPTAN1 SPTBN5 HPR	6.59e-05	30	167	4	CID000025738
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA	MAP1B PRSS16 HOXA1 HOXB9 NF1 HERC3 GNAS PLK4	6.89e-05	185	167	8	986_UP
Drug	Myricetin [529-44-2]; Down 200; 12.6uM; HL60; HT_HG-U133A	ROGDI CCDC22 DYNC2H1 CES2 DGLUCY ARHGEF40 NF1 EXOC7	8.30e-05	190	167	8	1334_DN
Drug	geldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A_EA	CYP1A1 CCDC22 TDRD7 CLMN TLE3 SLC22A5 GGPS1 FOXC1	8.61e-05	191	167	8	1008_DN
Drug	2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A	MAP1B DYNC2H1 FRY ARHGEF40 NF1 BUB1 AKT2 NPAS2	9.26e-05	193	167	8	5600_UP
Drug	PF-00562151-00 [351320-12-2]; Down 200; 10uM; PC3; HT_HG-U133A	KERA ARHGAP35 FAS ITGB8 SPTBN5 NF1 CLMN RABEP1	9.26e-05	193	167	8	5922_DN
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A	EP400 SPTAN1 DENND4C CLMN RABEP1 TLE3 MACF1 EXOC7	9.59e-05	194	167	8	1670_DN
Drug	yohimbine; Up 200; 22.9uM; MCF7; HT_HG-U133A_EA	CYP1A1 NCSTN ARHGAP35 CES2 NF1 RABEP1 ARIH2 GDF11	9.59e-05	194	167	8	1119_UP
Drug	Dicyclomine hydrochloride [67-92-5]; Down 200; 11.6uM; PC3; HT_HG-U133A	EPPK1 IFT74 IRF5 CES2 HOXA1 ARHGEF40 CELSR2 BUB1	9.94e-05	195	167	8	4581_DN
Drug	Metaraminol bitartrate [33402-03-8]; Down 200; 8.6uM; PC3; HT_HG-U133A	IFT74 DAB2 EVC TLE3 GNAS GGPS1 FOXC1 NPAS2	9.94e-05	195	167	8	7368_DN
Drug	Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; PC3; HT_HG-U133A	MAP1B TBX21 SPOCK2 ARHGAP35 CRHR1 CES2 NF1 BUB1	9.94e-05	195	167	8	4211_UP
Drug	Nisoxetine hydrochloride [57754-86-6]; Down 200; 13uM; PC3; HT_HG-U133A	MAP1B IFT74 IRF5 ARHGAP35 ZFPL1 CES2 NF1 HERC3	1.03e-04	196	167	8	5091_DN
Drug	SB 202190; Up 200; 1uM; MCF7; HT_HG-U133A	RAB35 ANPEP MAP1B SPOCK2 ARHGAP35 ZFPL1 NF1 AKT2	1.03e-04	196	167	8	6887_UP
Drug	Vidarabine [5536-17-4]; Up 200; 15uM; HL60; HT_HG-U133A	A2M CYP1A1 NXPE4 HOXA1 TLR4 GNAS PLK4 VPS13B	1.03e-04	196	167	8	2706_UP
Drug	Mefenamic acid [61-68-7]; Up 200; 16.6uM; PC3; HT_HG-U133A	A2M IRF5 ARHGEF40 NF1 TLR4 PLK4 CNN1 EDRF1	1.03e-04	196	167	8	5109_UP
Drug	fluazifop-butyl	CYP1A1 CES1 CES2	1.05e-04	13	167	3	CID000050897
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	CYP1A1 PRSS16 IFT74 SPTAN1 IRF5 FBXL6 NF1 BMP15	1.07e-04	197	167	8	6940_UP
Drug	2-propylpentanoic acid; Up 200; 1000uM; PC3; HT_HG-U133A	CYP1A1 UBR4 SPOCK2 FAS ARHGEF40 AKT2 FOXG1 EDRF1	1.07e-04	197	167	8	4433_UP
Drug	Vitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A	ARHGAP35 ITGB8 NF1 ADAMTS20 FOXG1 EDRF1 BMP15 NPAS2	1.07e-04	197	167	8	3798_DN
Drug	Doxazosin mesylate [77883-43-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A	USP34 EPPK1 DYNC2H1 ARHGAP35 BCR CES2 TLE3 ARIH2	1.07e-04	197	167	8	4988_DN
Drug	Cephapirin sodium salt [24356-60-3]; Up 200; 9uM; PC3; HT_HG-U133A	RAB35 ZMYND11 PRSS16 TLE3 VPS35L EXOC7 PLK4 EDRF1	1.07e-04	197	167	8	7142_UP
Drug	Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; PC3; HT_HG-U133A	RAB35 EPPK1 IFT74 SPTAN1 CES2 FBXL6 RABEP1 GNAS	1.07e-04	197	167	8	5044_DN
Drug	Sulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A	FAS NF1 SMG7 HOXD1 RABEP1 PI4KB BUB1 FOXG1	1.07e-04	197	167	8	3769_DN
Drug	Thonzonium bromide [553-08-2]; Down 200; 6.8uM; MCF7; HT_HG-U133A	IRF5 ARHGAP35 ZFPL1 CES2 NF1 TLE4 PLK4 BMP15	1.11e-04	198	167	8	5678_DN
Drug	Bacitracin [1405-87-4]; Down 200; 2.8uM; MCF7; HT_HG-U133A	CYP1A1 USP34 RAB35 CCDC22 IRF5 NF1 SMG7 ARIH2	1.11e-04	198	167	8	6488_DN
Drug	Dubinidine [22964-77-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A	ROGDI EPPK1 EP400 IFT74 CES2 NF1 TLE3 EXOC7	1.11e-04	198	167	8	6250_DN
Drug	Paroxetine maleate [64006-44-6]; Up 200; 1uM; PC3; HT_HG-U133A	ZFPL1 NF1 HOXD1 TLR4 BUB1 PLK4 CNN1 EDRF1	1.11e-04	198	167	8	4556_UP
Drug	Metformin hydrochloride [1115-70-4]; Up 200; 24.2uM; MCF7; HT_HG-U133A	USP34 RAB35 DYNC2H1 ZFPL1 NF1 RABEP1 EXOC7 PLK4	1.11e-04	198	167	8	1694_UP
Disease	Malignant neoplasm of breast	GPI CYP1A1 ERCC6 RAPH1 DYNC2H1 SPTAN1 UBR4 TTC3 GALNT16 CRHR1 HOXB9 NLRP9 NF1 TLE3 SYNE2 ANKRD30A MACF1 AKT2 BCAR3 VPS13B	2.38e-06	1074	164	20	C0006142
Disease	primary biliary cirrhosis	KIF21B TET2 IRF5 WDFY4 ITGB8 CTLA4 PRORP	9.97e-06	133	164	7	EFO_1001486
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	DNAH10 CES1 GARS1 USP24 SPG11 CES2 CELSR2 SYNE2 MACF1	3.89e-05	291	164	9	EFO_0008317, EFO_0020946
Disease	acute myeloid leukemia (is_implicated_in)	TET2 CYP1A1 FAS NF1 CTLA4	1.08e-04	84	164	5	DOID:9119 (is_implicated_in)
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	PITPNM2 DNAH10 GARS1 USP24 SPG11 CELSR2 SYNE2 MACF1	1.21e-04	264	164	8	EFO_0008317, EFO_0020944
Disease	body fat distribution	PITPNM2 CYP1A1 DIP2B CPZ CCDC178 ITGB8 UBE4A	1.43e-04	202	164	7	EFO_0004341
Disease	hydrocephalus (implicated_via_orthology)	CELSR2 POMK HYDIN	1.53e-04	19	164	3	DOID:10908 (implicated_via_orthology)
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	CES1 SPG11 CES2 CELSR2 SYNE2 MACF1	1.59e-04	144	164	6	EFO_0004611, EFO_0020943
Disease	acute myeloid leukemia (is_marker_for)	GPI TET2 FAS NF1	1.60e-04	49	164	4	DOID:9119 (is_marker_for)
Disease	Myelofibrosis	MPL TET2	1.83e-04	4	164	2	C0026987
Disease	haptoglobin measurement	HPR CMTR2 HYDIN	2.08e-04	21	164	3	EFO_0004640
Disease	chronic myeloid leukemia (is_implicated_in)	CYP1A1 FAS BCR	2.08e-04	21	164	3	DOID:8552 (is_implicated_in)
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	CES1 GARS1 USP24 SPG11 CES2 CELSR2 MACF1	2.76e-04	225	164	7	EFO_0008317, EFO_0020947
Disease	hepatocellular adenoma (biomarker_via_orthology)	A2M HPR	3.04e-04	5	164	2	DOID:0050868 (biomarker_via_orthology)
Disease	systemic lupus erythematosus (is_implicated_in)	CYP1A1 IRF5 FAS CTLA4	3.99e-04	62	164	4	DOID:9074 (is_implicated_in)
Disease	Liver Cirrhosis, Experimental	A2M MYO5A HYKK SPTAN1 BMF LBP FAS BCR CES2 COLEC12 FRY TLR4 NPAS2	4.09e-04	774	164	13	C0023893
Disease	chronic obstructive pulmonary disease (is_implicated_in)	CYP1A1 CRHR1 TLR4 CTLA4	4.24e-04	63	164	4	DOID:3083 (is_implicated_in)
Disease	rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement	RGS22 IRF5 WDFY4 CTLA4	4.24e-04	63	164	4	EFO_0000685, EFO_0007791, EFO_0009459
Disease	Sezary Syndrome	TET2 IL32 CTLA4	4.47e-04	27	164	3	C0036920
Disease	VACTERL association (implicated_via_orthology)	DYNC2H1 QSOX1	4.54e-04	6	164	2	DOID:14679 (implicated_via_orthology)
Disease	Congenital muscular dystrophy (disorder)	SYNE2 POMK	4.54e-04	6	164	2	C0699743
Disease	malaria (is_marker_for)	TBX21 CTLA4	4.54e-04	6	164	2	DOID:12365 (is_marker_for)
Disease	glucagon measurement, glucose tolerance test	MACF1 HERC1	4.54e-04	6	164	2	EFO_0004307, EFO_0008463
Disease	Primary Myelofibrosis	MPL TET2	4.54e-04	6	164	2	C0001815
Disease	sexual dimorphism measurement	PITPNM2 TET2 DIP2B RAPGEF6 EPPK1 DNAH10 PRSS16 FRYL CNBD2 SPTBN5 ARHGEF40 NF1 SLC22A5 CDK5RAP1 MACF1 HERC1	4.67e-04	1106	164	16	EFO_0021796
Disease	Colorectal Carcinoma	TET2 ERCC6 MAP1B NDST3 NF1 HOXD1 CFAP77 TLR4 BUB1 GNAS UHRF2 EDRF1	5.86e-04	702	164	12	C0009402
Disease	Age related macular degeneration	ERCC6 HMCN1 TLR4	6.13e-04	30	164	3	C0242383
Disease	Severe Congenital Microcephaly	ERCC6 PLK4 FOXG1	6.76e-04	31	164	3	C3853041
Disease	stomach cancer (is_implicated_in)	TET2 CYP1A1 IL32 ERCC6	7.05e-04	72	164	4	DOID:10534 (is_implicated_in)
Disease	multiple sclerosis (is_implicated_in)	A2M IRF5 FAS CTLA4	7.43e-04	73	164	4	DOID:2377 (is_implicated_in)
Disease	pulse pressure measurement	TET2 LETM2 USP34 DIP2B MAP1B RAPH1 DYNC2H1 IRF5 FRYL FAS FAM186B DENND4C QSOX1 COG5 CMTR2 HYDIN SCAI NPAS2	7.70e-04	1392	164	18	EFO_0005763
Disease	Microlissencephaly	ERCC6 PLK4 FOXG1	8.14e-04	33	164	3	C1956147
Disease	alpha-2-macroglobulin measurement	A2M TET2	8.41e-04	8	164	2	EFO_0020138
Disease	Polycythemia Vera	MPL TET2	8.41e-04	8	164	2	C0032463
Disease	melanoma (is_implicated_in)	FAS TLR4 CTLA4	8.89e-04	34	164	3	DOID:1909 (is_implicated_in)
Disease	ovarian neoplasm	ERCC6 HOXB9 HOXD1 TLR4 AKT2	9.36e-04	134	164	5	C0919267
Disease	neuroimaging measurement	KIF21B DIP2B MAP1B FRYL ARHGAP35 BCR DENND4C NF1 TLE4 TLR4 ADAMTS20 MACF1 FOXG1 SCAI IPO11	9.57e-04	1069	164	15	EFO_0004346
Disease	atopic dermatitis (is_marker_for)	IL32 TLR4 CTLA4	9.68e-04	35	164	3	DOID:3310 (is_marker_for)
Disease	Malignant neoplasm of ovary	ERCC6 HOXB9 HOXD1 TLR4 AKT2	1.03e-03	137	164	5	C1140680
Disease	Behcet's disease (is_implicated_in)	CYP1A1 TLR4 CTLA4	1.05e-03	36	164	3	DOID:13241 (is_implicated_in)
Disease	obesity (implicated_via_orthology)	DNAH10 LBP CAPN11 HPR TLR4 ADAMTS20	1.32e-03	215	164	6	DOID:9970 (implicated_via_orthology)
Disease	obstructive jaundice (biomarker_via_orthology)	IRF5 LBP	1.34e-03	10	164	2	DOID:13603 (biomarker_via_orthology)
Disease	hepatocellular carcinoma (is_marker_for)	TET2 IL32 CES1 FAS TLR4 CTLA4 PLK4	1.53e-03	301	164	7	DOID:684 (is_marker_for)
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	SPG11 CELSR2 SYNE2 SLC22A5 MACF1	1.54e-03	150	164	5	EFO_0004611, EFO_0020947
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	PITPNM2 USP24 SPG11 CELSR2 SYNE2 MACF1	1.56e-03	222	164	6	EFO_0008317, EFO_0020943
Disease	Systemic lupus erythematosus	IRF5 CTLA4	1.63e-03	11	164	2	cv:C0024141
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	MAP1B PI4KB	1.63e-03	11	164	2	DOID:0050564 (is_implicated_in)
Disease	primary immunodeficiency disease (is_implicated_in)	TET2 TBX21 CTLA4	1.65e-03	42	164	3	DOID:612 (is_implicated_in)
Disease	aspartate aminotransferase measurement	KIF21B IL32 RAPGEF6 ANPEP DAB2 ARHGAP35 DGLUCY NF1 HPR TLE4 CTLA4 MYO15A NPAS2	1.68e-03	904	164	13	EFO_0004736
Disease	fibrinogen measurement, coronary artery disease	DIP2B RAPGEF6 RAPH1 DYNC2H1 CELSR2	1.73e-03	154	164	5	EFO_0001645, EFO_0004623
Disease	triglycerides in large LDL measurement	CELSR2 HPR SYNE2	1.77e-03	43	164	3	EFO_0022319
Disease	Paroxysmal atrial fibrillation	USP34 DNAH10 SYNE2 HERC1 COG5	1.83e-03	156	164	5	C0235480
Disease	familial atrial fibrillation	USP34 DNAH10 SYNE2 HERC1 COG5	1.83e-03	156	164	5	C3468561
Disease	Persistent atrial fibrillation	USP34 DNAH10 SYNE2 HERC1 COG5	1.83e-03	156	164	5	C2585653
Disease	Thrombocythemia, Essential	MPL TET2	1.95e-03	12	164	2	C0040028
Disease	Myeloproliferative disease	MPL BCR	1.95e-03	12	164	2	C0027022
Disease	Atrial Fibrillation	USP34 DNAH10 SYNE2 HERC1 COG5	2.05e-03	160	164	5	C0004238
Disease	hearing impairment	ERCC6 TLR4 MYO15A FOXC1	2.21e-03	98	164	4	C1384666
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	DNAH10 CES1 CES2 CELSR2 SLC22A5 MACF1	2.45e-03	243	164	6	EFO_0004612, EFO_0020944
Disease	Major Depressive Disorder	ANPEP RAPH1 TBX21 BCR CRHR1 CTLA4	2.45e-03	243	164	6	C1269683
Disease	multiple sclerosis (is_marker_for)	IL32 FAS TLR4	2.57e-03	49	164	3	DOID:2377 (is_marker_for)
Disease	Mammary Carcinoma, Human	GPI CYP1A1 DYNC2H1 GALNT16 CRHR1 HOXB9 TLE3 AKT2 BCAR3	2.78e-03	525	164	9	C4704874
Disease	Mammary Neoplasms, Human	GPI CYP1A1 DYNC2H1 GALNT16 CRHR1 HOXB9 TLE3 AKT2 BCAR3	2.78e-03	525	164	9	C1257931
Disease	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	DNAH10 ITGB8 DGLUCY HOXC12	2.84e-03	105	164	4	EFO_0007788, EFO_0008007, EFO_0008343
Disease	Mammary Neoplasms	GPI CYP1A1 DYNC2H1 GALNT16 CRHR1 HOXB9 TLE3 AKT2 BCAR3	2.85e-03	527	164	9	C1458155
Disease	lung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma	TET2 DYNC2H1 FRY	3.05e-03	52	164	3	EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Disease	Breast Carcinoma	GPI CYP1A1 DYNC2H1 GALNT16 CRHR1 HOXB9 TLE3 AKT2 BCAR3	3.27e-03	538	164	9	C0678222
Disease	Unipolar Depression	ANPEP RAPH1 TBX21 BCR CRHR1 CTLA4	3.36e-03	259	164	6	C0041696
Disease	Autistic Disorder	ZMYND11 RNF8 WDFY4 HOXA1 NF1 NPAS2	3.49e-03	261	164	6	C0004352
Disease	triglycerides in medium VLDL measurement	DNAH10 CELSR2 HPR	3.58e-03	55	164	3	EFO_0022155
Disease	waist-hip ratio	TET2 ZMYND11 DNAH10 DYNC2H1 DAB2 ITGB8 CRHR1 TDRD7 DGLUCY HOXC12 SYNE2 ADAMTS20 FOXC1 SCAI NPAS2	3.58e-03	1226	164	15	EFO_0004343
Disease	non-melanoma skin carcinoma	PRSS16 RGS22 CNBD2 CDK5RAP1 CTLA4 MYO15A	3.75e-03	265	164	6	EFO_0009260
Disease	triglycerides in LDL measurement	CELSR2 HPR SYNE2	3.77e-03	56	164	3	EFO_0022320
Disease	creatinine measurement	KIF21B TET2 CYP1A1 DAB2 EVC BTAF1 FRY CELSR2 SLC22A5 AKT2 GNAS BCAR3 UHRF2	3.83e-03	995	164	13	EFO_0004518
Disease	red blood cell density measurement	TET2 POLR1A EP400 DNAH10 MYO9A ARHGEF40 DST RABEP1 TLE3 MYO15A UHRF2 VPS13B	3.87e-03	880	164	12	EFO_0007978
Disease	level of Sphingomyelin (d32:1) in blood serum	RABEP1 SYNE2	3.95e-03	17	164	2	OBA_2045173
Disease	dermatomyositis (is_marker_for)	FAS TLR4	3.95e-03	17	164	2	DOID:10223 (is_marker_for)
Disease	apolipoprotein B measurement	DNAH10 RAPH1 TBX21 USP24 NF1 CELSR2 HPR SYNE2 SLC22A5 HYDIN	4.09e-03	663	164	10	EFO_0004615
Disease	colon cancer (is_marker_for)	IL32 NF1 PLK4	4.36e-03	59	164	3	DOID:219 (is_marker_for)
Disease	Age-related macular degeneration	ERCC6 HMCN1	4.43e-03	18	164	2	cv:C0242383
Disease	Anorexia	CRHR1 GIP	4.43e-03	18	164	2	C0003123
Disease	Tourette syndrome, schizophrenia	PITPNM2 DNAH10	4.43e-03	18	164	2	EFO_0004895, MONDO_0005090
Disease	Sjogren's syndrome (is_implicated_in)	CYP1A1 CTLA4	4.43e-03	18	164	2	DOID:12894 (is_implicated_in)
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	SPG11 CELSR2 SYNE2 MACF1	4.72e-03	121	164	4	EFO_0008595, EFO_0020943
Disease	pain	PRSS16 SPOCK2 CRHR1 CELSR2 MACF1	4.88e-03	196	164	5	EFO_0003843
Disease	testosterone measurement	TET2 DIP2B POLR1A MYO5A BMF FAS UBE4A ARHGEF40 NF1 HMCN1 SYNE2 MACF1 MYH16 MYO15A FOXC1	5.12e-03	1275	164	15	EFO_0004908
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	DNAH10 SPG11 CELSR2 SYNE2 MACF1	5.31e-03	200	164	5	EFO_0004611, EFO_0020945
Disease	myelodysplastic syndrome (is_marker_for)	FAS SLC22A5	5.46e-03	20	164	2	DOID:0050908 (is_marker_for)
Disease	uridine diphosphate measurement	ZMYND11 PTCHD3	5.46e-03	20	164	2	EFO_0010545
Disease	atherosclerosis (biomarker_via_orthology)	FAS HPR	5.46e-03	20	164	2	DOID:1936 (biomarker_via_orthology)
Disease	brain age measurement	EEF1AKMT4-ECE2 ECE2	5.46e-03	20	164	2	EFO_0010602
Disease	rheumatoid arthritis, COVID-19	IRF5 FRYL IFNGR2	5.48e-03	64	164	3	EFO_0000685, MONDO_0100096

Protein segments in the cluster

Peptide	Gene	Start	Entry
HRFFLSINWQDVVQK	AKT2	406	P31751
HLDQVAALRWVQDNI	CES1	191	P23141
HWEAVFTLQSQQRLL	EP400	1231	Q96L91
QVHLQGLQKVVFRSW	C1orf167	991	Q5SNV9
SIAQLLWRQAAHNKE	ARHGEF40	1366	Q8TER5
LWRQAAHNKELRVQQ	ARHGEF40	1371	Q8TER5
QHRYLQLWVQEQKAT	CFAP77	221	Q6ZQR2
AQKYNQRRKHEQWVN	BUB1	256	O43683
TEHGQFRQKWRLNKN	CRYBG3	2911	Q68DQ2
QWKNLAQHFKINRTV	BCAR3	191	O75815
WSHQQRVGDLFQKLA	BCR	571	P11274
QRHWQEITFNLPVKQ	ALG6	41	Q9Y672
SNQEHQWLFSRLQDV	ARHGEF5	1211	Q12774
LNIQDAQKRTALHWA	ANKRD30A	66	Q9BXX3
QKFQLKHLSRNNWLV	CMTR2	406	Q8IYT2
FLHLLRNVNKQWITF	COX10	36	Q12887
DKIHQQDFVNWLLAQ	GIP	66	P09681
RWENHNKSLQLEAQT	ARIH2	371	O95376
NLWDHLQEAVNNRSI	ANPEP	516	P15144
LDTANKRHWELIQQT	CELSR2	2116	Q9HCU4
QQRQKKWALLEQEHQ	FAM186B	501	Q8IYM0
NRFSQLQRLTLIHWK	FBXL6	191	Q8N531
QRLQKQLTEHLRQSW	CCDC22	246	O60826
KNWRHARQQGAQLQT	CAPN11	451	Q9UMQ6
WANHVLQVLIQFKVN	BBS12	396	Q6ZW61
SHLENRKQQLQQEQW	CCDC121	221	Q6ZUS5
WHKQGQRVLLFSQSR	ERCC6	851	Q03468
TKQRQVWCQLNVDHL	ADAMTS20	1041	P59510
AHITQALIWLSQRQK	A2M	1061	P01023
FWLQNLRAKQGEALH	ANO8	171	Q9HCE9
QAWLFSDHLIQQQGK	GALNT16	471	Q8N428
VWANRHLQLIAQKLY	NWD2	731	Q9ULI1
NLANFVKSWTNLRLQ	NDST3	536	O95803
NLLNWTRDSQNKLIF	RAPH1	336	Q70E73
RFKLQAWEVLHNVAS	NOXA1	116	Q86UR1
FVNVKRWLHEINQNC	RAB35	96	Q15286
LVQNFLHSVNEWLKR	QSOX1	346	O00391
LEQERQQHNQLKHTW	RABEP1	266	Q15276
CVFVNQWQINHDQKL	CYP1A1	406	P04798
LIKANNSWFQSILRQ	NCSTN	526	Q92542
LQANIRWQQEELHKI	NPAS2	516	Q99743
QGQHKQRIWVNISLS	DAB2	86	P98082
LNLSDQQVKIWFQNR	HOXC12	251	P31275
QLRQQLTEWQDLHLK	LETM2	361	Q2VYF4
WLLNLFHNQIESKFQ	LBP	176	P18428
QGWFNIRKSINVIQH	nan	571	O00370
WKNSNLDRHNLQDFI	MAP1B	196	P46821
LHLNDTQVKIWFQNR	HOXD1	266	Q9GZZ0
WLNLVSQHRQQTQAL	MYO15A	3381	Q9UKN7
HSQGLKNDFVRNILW	EDRF1	296	Q3B7T1
LAWAKQHQQRLASAL	DST	7016	Q03001
TIAVWRQKLSEHNNA	HERC3	406	Q15034
EQWLLTTAKNLFLNH	HPR	136	P00739
LNIFTNHTLDINVRW	IPO11	46	Q9UI26
SQHRQWAAQQLVRTL	HERC1	3381	Q15751
KLNQLQEWQLHRTGL	LRRC39	81	Q96DD0
ITQLVQQRFWNNKGH	BMP15	186	O95972
LQWHLEDKANQLQHF	CCDC178	231	Q5BJE1
NSLWDQNQAILKHLL	ECE2	191	P0DPD6
GLLQVSQVNKHWNRI	FBXW12	21	Q6X9E4
NKQGWQNSIRHNLSL	FOXG1	221	P55316
HLVFINTREEQQWIK	COLEC12	641	Q5KU26
QVAALRWVQQNIAHF	CES2	201	O00748
LCVSQKQFFLNNWHI	FRYL	321	O94915
VSSIVRQWNRKINHF	KIF21B	866	O75037
RKHQFLAEILQWRAQ	DIP2B	986	Q9P265
FEEVLTWAKQHQQRL	MACF1	2986	O94854
QKLQQWYREHRSELN	GPI	11	P06744
QVRTKLSQAFNHWLK	GGPS1	26	O95749
EQFKELHHIWQSQQR	IRF5	456	Q13568
LQLNETQVKIWFQNR	HOXA1	266	P49639
MQKQRVVAWLAQHNF	PITPNM2	1156	Q9BZ72
HIEQQIQTYQRSWLK	EXOC7	611	Q9UPT5
TWNSRLLHFQNAVEI	MACF1	3466	Q9UPN3
RTLQNQLVELKNHWE	MACF1	4876	Q9UPN3
QNVWRVSHINSNYKL	MTMR4	171	Q9NYA4
NWRKNGHLLNVDQNQ	HMCN1	3836	Q96RW7
LLNLSERQVKIWFQN	HOXB9	221	P17482
NINVIFAVQGKQFHW	ITGB8	336	P26012
NDLWKRLQQYSQHIQ	COG5	421	Q9UP83
FQFWIEQAHRGNKQI	DYNC2H1	176	Q8NCM8
DEYLQNLNHIQRKWV	DYNC2H1	1336	Q8NCM8
TFNSLWDQNQAILKH	EEF1AKMT4-ECE2	261	P0DPD8
WDQNQAILKHLLENT	EEF1AKMT4-ECE2	266	P0DPD8
VALVHAVQALWKQFQ	IL32	181	P24001
NIIAHFLWKVFATQQ	HYDIN	326	Q4G0P3
NETHSQLTNLERKWQ	IFT74	536	Q96LB3
QLTNLERKWQHLEQN	IFT74	541	Q96LB3
LSSLHRENFIWNLKN	HYKK	166	A2RU49
ILWQHNKESLLNFVE	CPZ	486	Q66K79
NQEWQVLQLRVHTFA	BTAF1	846	O14981
RDNKQGWQNSIRHNL	FOXC1	116	Q12948
LAFSKTQHINNWLTN	CEP126	301	Q9P2H0
LANTFRQVAQLHWIL	B3GAT2	101	Q9NPZ5
QSIDFKQVLHSWFRQ	GDF11	236	O95390
VYIQLLWDNINLHQE	DENND4C	1766	Q5VZ89
LQEALNLFKSIWNNR	GNAS	266	P63092
NIIHWNLISAFILRN	CRHR1	181	P34998
QNRVWWQILLFLHNL	BMF	156	Q96LC9
QVQAQLLWNKSNIFR	IFNGR2	211	P38484
HWQIQQALKRAQASK	CCDC38	231	Q502W7
FQRHKAQLNLATRTW	CTLA4	6	P16410
LLTQQHKAFWQEAER	EVC	421	P57679
VSQKQLFLNRWHIFL	FRY	371	Q5TBA9
VAIIVDQRAWNLHQK	DGLUCY	371	Q7Z3D6
SSWNLKILQINQLHL	CA5BP1	16	Q8WTZ4
NQLHLVHWNAVKFEN	CA5BP1	26	Q8WTZ4
LRHLANTVQENAKSW	DNAH10	1051	Q8IVF4
QQSHNILDLLRTWNI	SLC22A5	326	O76082
TTWRKAILQNVGQNH	CFAP47	971	Q6ZTR5
WEQTQKIYNCHVLLN	NIT1	136	Q86X76
QWLTHLLDQFTNIKN	PTCHD3	341	Q3KNS1
KQWKLQQIQDARNHV	ROGDI	106	Q9GZN7
NLQWFILTKAQQARE	TCAIM	396	Q8N3R3
IAQQDYWRILNHVEK	RAPGEF6	371	Q8TEU7
KLYNIWIRLQSHVNI	POLR1A	386	O95602
LKQQLAQALQEHWAL	RNF8	336	O76064
KQWIVDFVNQSLLQL	SYNE2	5111	Q8WXH0
NTHKRWTQVNQAIAD	SYNE2	5361	Q8WXH0
LNKINDRWQHLFDVI	SYNE2	5996	Q8WXH0
HQLAVDLDRNINIQW	NXPE4	381	Q6UWF7
KHVQNRLENVWLPLF	RGS22	956	Q8NE09
VEQDLWNHAFKNQIT	SMG7	56	Q92540
WNHAFKNQITTLQGQ	SMG7	61	Q92540
ETSNKHLWFQGIRRQ	EPPK1	2166	P58107
ALKNNIIQTWRQHFI	GARS1	156	P41250
FENATQLRWINLNKN	KERA	91	O60938
LEDIWTKLNQIIRHN	SHLD3	181	Q6ZNX1
LSKYQNVNTWQHRLE	POMK	166	Q9H5K3
IKALSWNRQAQHILS	SEC31B	171	Q9NQW1
SINRQITNADLWKHQ	TDRD7	831	Q8NHU6
WRQVQKAPNLHLQQS	TEX45	381	Q8NA69
QNNSAKQSWLLRLFE	PI4KB	121	Q9UBF8
VQQWFGNLQINAHLR	PLK4	476	O00444
AKTQRLFFKWQQGHQ	PRORP	511	O15091
LFFKWQQGHQLAIVN	PRORP	516	O15091
VSRIVKNHNENWLSV	ARHGAP35	281	Q9NRY4
IHLWQERLQQLDAQS	SPTBN5	1151	Q9NRC6
ENVQKRTFTRWINLH	CLMN	31	Q96JQ2
QNSWNIFRKDLLQLL	CNBD2	491	Q96M20
NWHQLENIGNFIKAI	CNN1	81	P51911
AEQTIWNRLHQLKAL	CDK5RAP1	151	Q96SZ6
KQAWEVTLNLFLQIN	NLRP9	66	Q7RTR0
EFNKQDHRIVLNWAL	SPG11	841	Q96JI7
AKANDWLQFIIHSQL	SPG11	1366	Q96JI7
LENVENLLHNRNFWI	ZNF767P	81	Q75MW2
QQHLIREDCQNQKLW	UHRF2	696	Q96PU4
QTFRWASNLQRHQKN	ZNF707	211	Q96C28
LNRLWNTKSDLHQNT	ZC3H6	911	P61129
NNKLNQLSVNLWHLA	VPS35L	906	Q7Z3J2
AEQKVQLLRNWHQLH	FAS	271	P25445
IAVWDLHNQTLVRQF	TLE4	601	Q04727
IQQRLAQFVEHWKEL	SPTAN1	1841	Q13813
QLVLITAFAHSWNKN	SERINC4	196	A6NH21
HNIQKTVQTLWQQLV	WDFY4	2116	Q6ZS81
KAFRWGNQLTQHQKI	ZNF331	166	Q9NQX6
KINIFWPLLFQHQNS	TTC3	86	P53804
QHNFLKNWQRNTALR	MYCBPAP	201	Q8TBZ2
ALHRLLWNNQEKIGQ	NF1	1506	P21359
LWKFQQQHRQVLDNR	SCAI	101	Q8N9R8
PLHLWVKNVFLNQTR	MPL	106	P40238
LQRQLKNIQDISWHT	TAS1R2	471	Q8TE23
AVWDLHNQTLVRQFQ	TLE3	601	Q04726
IQQNVHKFLQLRFWG	MYH16	6	Q9H6N6
KSNWRQQHEDFINAI	ZC2HC1B	76	Q5TFG8
QHLWAAIEIIRNQKQ	ZMYND11	16	Q15326
SDQLNHLFVLIQKSW	USP24	506	Q9UPU5
VHSLNTAIQAWQQNK	VPS13B	2606	Q7Z7G8
QQKLWHLFQNSATAV	TAPR1	56	Q14CZ0
VNSLQHRVKNRVWQT	TARBP1	1161	Q13395
QLASHQNIQWAFKNL	USP34	2871	Q70CQ2
KINQNLHRLQVAWRD	UBE4A	531	Q14139
LKLGHNNWLRQVLFT	UBR4	4121	Q5T4S7
ALRWHLLQKQEQQQT	TET2	951	Q6N021
EHQSFLQWIKDQRQL	TLR4	586	O00206
RQNIFQQLQTWLKLA	PRSS16	491	Q9NQE7
LNNHLLWSKFNQHQT	TBX21	141	Q9UL17
LIIHLKRFQFVNDQW	USP6	1076	P35125
DTTLWHFQRNQTVQK	ZNF891	251	A8MT65
NHAKCIVQSYLQWLQ	ZFPL1	31	O95159
QNRRVQWLQGFAKLH	TEX13B	86	Q9BXU2
LRDWFQLLHENSKQN	SPOCK2	211	Q92563
LFNWIVDNVNQALHS	MYO5A	411	Q9Y4I1
NIHVIASVFKQWLRD	MYO9A	2126	B2RTY4