Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal sphenoid bone morphology

MEMO1 APAF1 HMGXB3 SIM2 NIPBL

1.43e-0595465MP:0000104
MousePhenoabnormal basicranium morphology

MEMO1 SMG1 TMEM67 APAF1 HMGXB3

4.99e-05123465MP:0010029
MousePhenoabnormal fourth ventricle morphology

TMEM67 APAF1 NPAS3

7.29e-0525463MP:0000828
MousePhenoabnormal craniofacial morphology

MEMO1 RGMA SMG1 TMEM67 ZFHX4 LRIG1 VCAN SPTBN1 APAF1 POLR1B HMGXB3 SIM2 LYST NIPBL

8.46e-0513724614MP:0000428
MousePhenocraniofacial phenotype

MEMO1 RGMA SMG1 TMEM67 ZFHX4 LRIG1 VCAN SPTBN1 APAF1 POLR1B HMGXB3 SIM2 LYST NIPBL

8.46e-0513724614MP:0005382
DomainSIM_C

SIM1 SIM2

9.81e-062592IPR010578
DomainSIM_C

SIM1 SIM2

9.81e-062592PF06621
DomainSIM_C

SIM1 SIM2

9.81e-062592PS51302
DomainPAS_fold_3

NPAS3 SIM1 SIM2

5.07e-0523593IPR013655
DomainPAS_3

NPAS3 SIM1 SIM2

5.07e-0523593PF08447
DomainPAS-assoc_C

NPAS3 SIM1 SIM2

5.78e-0524593IPR000700
DomainPAS

NPAS3 SIM1 SIM2

6.55e-0525593PF00989
DomainPAS_fold

NPAS3 SIM1 SIM2

6.55e-0525593IPR013767
DomainPAC

NPAS3 SIM1 SIM2

7.39e-0526593IPR001610
DomainPAC

NPAS3 SIM1 SIM2

7.39e-0526593SM00086
DomainPAC

NPAS3 SIM1 SIM2

7.39e-0526593PS50113
DomainPAS

NPAS3 SIM1 SIM2

1.39e-0432593SM00091
DomainPAS

NPAS3 SIM1 SIM2

1.67e-0434593IPR000014
DomainPAS

NPAS3 SIM1 SIM2

1.67e-0434593PS50112
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH1

8.71e-0414592IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH1

8.71e-0414592IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH1

8.71e-0414592IPR013602
DomainDHC_N2

DNAH10 DNAH1

8.71e-0414592PF08393
DomainMT

DNAH10 DNAH1

8.71e-0414592PF12777
DomainAAA_8

DNAH10 DNAH1

8.71e-0414592PF12780
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH1

8.71e-0414592IPR011704
DomainAAA_5

DNAH10 DNAH1

8.71e-0414592PF07728
DomainDHC_fam

DNAH10 DNAH1

1.00e-0315592IPR026983
DomainDynein_heavy_dom

DNAH10 DNAH1

1.00e-0315592IPR004273
DomainDynein_heavy

DNAH10 DNAH1

1.00e-0315592PF03028
DomainABC_TM1F

ABCD2 TAP2

3.52e-0328592PS50929
DomainABC1_TM_dom

ABCD2 TAP2

3.52e-0328592IPR011527
DomainCadherin_CS

CDH22 PCDHGA12 PCDH20

4.96e-03109593IPR020894
Domain-

NPAS3 SIM1 SIM2

4.96e-031095934.10.280.10
DomainHLH

NPAS3 SIM1 SIM2

5.22e-03111593PF00010
DomainCADHERIN_1

CDH22 PCDHGA12 PCDH20

5.48e-03113593PS00232
DomainCadherin

CDH22 PCDHGA12 PCDH20

5.48e-03113593PF00028
DomainCADHERIN_2

CDH22 PCDHGA12 PCDH20

5.62e-03114593PS50268
Domain-

CDH22 PCDHGA12 PCDH20

5.62e-031145932.60.40.60
DomainCA

CDH22 PCDHGA12 PCDH20

5.75e-03115593SM00112
DomainHLH

NPAS3 SIM1 SIM2

5.89e-03116593SM00353
DomainCadherin-like

CDH22 PCDHGA12 PCDH20

5.89e-03116593IPR015919
DomainBHLH

NPAS3 SIM1 SIM2

6.04e-03117593PS50888
DomainbHLH_dom

NPAS3 SIM1 SIM2

6.18e-03118593IPR011598
DomainCadherin

CDH22 PCDHGA12 PCDH20

6.18e-03118593IPR002126
DomainABC_transporter_CS

ABCD2 TAP2

7.79e-0342592IPR017871
Pubmed

Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1.

CDH22 PREX1 SLC12A5

1.02e-07661318602983
Pubmed

Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.

CDH22 PREX1 SLC12A5

1.02e-07661320650312
Pubmed

Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.

SMG1 ZBTB43 APAF1 FAM20B

2.18e-06526149455477
Pubmed

A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM2.

SIM1 SIM2

3.03e-06261214697214
Pubmed

Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region.

SIM1 SIM2

3.03e-0626129199934
Pubmed

Single-minded--two genes, three chromosomes.

SIM1 SIM2

3.03e-0626129199929
Pubmed

Early pre-implantation lethality in mice carrying truncated mutation in the RNA polymerase 1-2 gene.

NPM1 POLR1B

3.03e-06261218023416
Pubmed

Overexpression of mSim2 gene in the zona limitans of the diencephalon of segmental trisomy 16 Ts1Cje fetuses, a mouse model for trisomy 21: a novel whole-mount based RNA hybridization study.

SIM1 SIM2

3.03e-06261210837894
Pubmed

Physical mapping of the holoprosencephaly critical region in 21q22.3, exclusion of SIM2 as a candidate gene for holoprosencephaly, and mapping of SIM2 to a region of chromosome 21 important for Down syndrome.

SIM1 SIM2

9.07e-0636127485157
Pubmed

cDNA cloning of a murine homologue of Drosophila single-minded, its mRNA expression in mouse development, and chromosome localization.

SIM1 SIM2

9.07e-0636128561800
Pubmed

Characterization of human variants in obesity-related SIM1 protein identifies a hot-spot for dimerization with the partner protein ARNT2.

SIM1 SIM2

9.07e-06361224814368
Pubmed

Characterization of msim, a murine homologue of the Drosophila sim transcription factor.

SIM1 SIM2

9.07e-0636128661115
Pubmed

Sim1 and Sim2 expression during chick and mouse limb development.

SIM1 SIM2

1.81e-05461219123137
Pubmed

Members of the bHLH-PAS family regulate Shh transcription in forebrain regions of the mouse CNS.

SIM1 SIM2

1.81e-05461211023872
Pubmed

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.

RGMA TMEM67 PARP4 HK1

2.96e-0510061426073538
Pubmed

Two murine homologs of the Drosophila single-minded protein that interact with the mouse aryl hydrocarbon receptor nuclear translocator protein.

SIM1 SIM2

3.02e-0556129020169
Pubmed

Digital quantification of human eye color highlights genetic association of three new loci.

HERC2 LYST

4.52e-05661220463881
Pubmed

Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis.

SIM1 SIM2

4.52e-0566128927054
Pubmed

NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.

NPAS3 SIM1

6.32e-05761227782878
Pubmed

MAGED1 is a novel regulator of a select subset of bHLH PAS transcription factors.

SIM1 SIM2

6.32e-05761227472814
Pubmed

Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.

RGMA LRIG1

8.42e-05861226651291
Pubmed

Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factors.

SIM1 SIM2

8.42e-05861211782478
Pubmed

Sim2 contributes to neuroendocrine hormone gene expression in the anterior hypothalamus.

SIM1 SIM2

8.42e-05861214988428
Pubmed

Sim2 mutants have developmental defects not overlapping with those of Sim1 mutants.

SIM1 SIM2

1.35e-041061212024028
Pubmed

Sim1 and Sim2 are required for the correct targeting of mammillary body axons.

SIM1 SIM2

1.97e-041261216291793
Pubmed

Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis.

NPM1 POLR1B

1.97e-041261215989966
Pubmed

Spatial gene expression in the T-stage mouse metanephros.

VCAN SIM1

1.97e-041261216545622
Pubmed

The murine Otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus.

SIM1 SIM2

2.33e-041361211071765
Pubmed

Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome.

SIM1 SIM2

2.33e-04136128812055
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH1

2.72e-04146129373155
Pubmed

Laminar organization of the early developing anterior hypothalamus.

SIM1 SIM2

3.57e-041661216860307
Pubmed

Gene expression profiling of the developing mouse kidney and embryo.

VCAN SIM2

5.63e-042061219998061
Pubmed

Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.

LRIG1 MYSM1

6.22e-042161225340873
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

RGMA ZGPAT HMGXB3 MICAL3 HERC2 LYST SCARA3 PREX1

6.70e-04110561835748872
Pubmed

Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity.

ESRRG SIM1

6.83e-042261238160393
Pubmed

Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.

NPAS3 SIM1 SIM2

6.93e-049861318557763
Pubmed

Genome-wide Identification of Foxf2 Target Genes in Palate Development.

VCAN SIM2

7.48e-042361232040930
Pubmed

Placentation defects are highly prevalent in embryonic lethal mouse mutants.

SMG1 PITRM1 HMGXB3

8.01e-0410361329539633
Pubmed

A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.

ZGPAT PRPF4 PELI3 NFYB NUDT9

8.47e-0441961528700943
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NPM1 SMG1 HK1 PCDHGA12 SPTBN1 STK31 LYST PREX1 NIPBL

8.77e-04144261935575683
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

SMG1 PARP4 NFYB STK31 PREX1 NIPBL

8.78e-0463861631182584
Pubmed

Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity.

NPM1 KIF24

1.03e-032761235709258
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

NPM1 ZGPAT HK1 SPTBN1 APAF1 POLR1B TAP2

1.15e-0392561728986522
Pubmed

Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly.

ZGPAT PRPF4

1.36e-033161228878014
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

RBSN LRIG1 PITRM1 SPTBN1 HMGXB3 RFTN2 KIF24 MYSM1

1.42e-03124261830973865
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

MEMO1 HK1 PRPF4 APAF1 POLR1B NIPBL

1.45e-0370461629955894
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

RBSN ESRRG ZBTB43 NPAS3 HMGXB3 SIM1

1.51e-0370961622988430
Pubmed

The spatiotemporal expression pattern of Syndecans in murine embryonic teeth.

VCAN FAM20B

1.64e-033461232220631
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PARP4 ZNF286B MICAL3 PREX1 MYSM1

1.74e-0349361515368895
CytobandEnsembl 112 genes in cytogenetic band chr20q13

ZGPAT CDH22 PREX1 SLC12A5

2.43e-03422614chr20q13
Cytoband1q41

CAPN8 ESRRG

3.53e-03666121q41
Cytoband2q13

NT5DC4 POLR1B

3.74e-03686122q13
GeneFamilyDyneins, axonemal

DNAH10 DNAH1

7.35e-0417432536
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NT5DC4 ZFHX4 VCAN NPAS3 SIM2 SCARA3

3.15e-07199616abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 ZFHX4 DNAH10 ESRRG SIM2

2.71e-06160615c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 ZFHX4 DNAH10 ESRRG SIM2

2.71e-0616061525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

LRIG1 DNAH10 LCA5L MUC13 ABCD2

4.81e-0618061585fc9b164147b28545e2397d32302eea03ef6346
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGMA ZFHX4 LRIG1 RFTN2 SCARA3

5.79e-06187615dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGMA ZFHX4 LRIG1 RFTN2 SCARA3

5.79e-061876154d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGMA ZFHX4 LRIG1 RFTN2 SCARA3

5.79e-06187615ae90c263f80c36a410150d499e268d198944a3d9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN8 ESRRG SIM1 SIM2 LYST

5.79e-0618761577886f99c229610abd28c4c370d2c7d1536c9782
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PARP4 ZFHX4 VCAN SIM2 SCARA3

5.79e-061876159225caf66e06ebe57e90d677122acb6498607f36
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

RGMA PARP4 LRIG1 NPAS3 RFTN2

8.02e-062006153a954d9d542e52c9b181f0850a09b1bff0a0c82d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 PARP4 ZFHX4 SCARA3

4.32e-051426146469cf82552b39f63e20b841c9eed50de6f58d54
ToppCellIIH-CD8-exh_CD4|IIH / Condition, Cell_class and T cell subcluster

ZGPAT KCNA7 SPTBN1 RFTN2

5.92e-05154614a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN8 ESRRG SIM2 LYST

7.20e-05162614373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PARP4 VCAN ESRRG SIM2

7.55e-051646141cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEMO1 RGMA FAM20B SIM2

8.10e-0516761429d271643f3a1718b53db77b7d093ec94225a824
ToppCellInt-URO-Lymphocyte-B-B_intermediate|Int-URO / Disease, Lineage and Cell Type

NPM1 FCRL3 RFTN2 SIM2

8.29e-051686145b3fb1fc8fea810c6d4e6feb42c24fb57e8066de
ToppCellwk_20-22-Mesenchymal-Chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PELI3 RFTN2 SIM2 SCARA3

8.88e-05171614d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LCA5L MUC13 NUDT9 STK31

8.88e-05171614317b70d72a4ca5336cfb6a49dc57f8e2a8a1c736
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRIG1 PCDHGA12 SPTBN1 SCARA3

9.71e-05175614e99e145a152f534b75267ec492a252a0b814b4f8
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM67 HK1 ZFHX4 MYBPC3

9.92e-051766144ed73c73972334f6dc4229920205547823252fa0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN8 ESRRG SIM2 LYST

1.13e-04182614a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 SPTBN1 LYST NIPBL

1.13e-04182614f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST10 CDH22 LRIG1 NPAS3

1.15e-0418361425c96df8ea0c7bbedbb7699ee84ad6234d19cba8
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 ZFHX4 DNAH10 DNAH1

1.18e-041846142cbed6462fea2622871bb7e49b0df3d984239281
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 SPTBN1 LYST NIPBL

1.18e-041846141154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 ZFHX4 DNAH10 DNAH1

1.18e-04184614ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 ZFHX4 DNAH10 DNAH1

1.18e-041846142b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RGMA PCDHGA12 VCAN SCARA3

1.18e-04184614d754c3de621429b220ae4ac426cdfc619e848462
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NPAS3 RFTN2 SIM2 SCARA3

1.20e-041856148ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST10 CDH22 LRIG1 NPAS3

1.20e-04185614dbbd348714cd16a4948a04648e914b1e71e2a8ef
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST10 CDH22 LRIG1 NPAS3

1.20e-04185614bea69058afa5aa927fe15c1f8d46460562ec4dd4
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 SPTBN1 LYST NIPBL

1.20e-041856147adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VCAN SPTBN1 ESRRG MUC13

1.20e-04185614d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NPAS3 RFTN2 SIM2 SCARA3

1.20e-04185614b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX4 VCAN RFTN2 PREX1

1.25e-0418761497e520705491c8f52a32025311a9fa7b9176979a
ToppCell15-Trachea-Epithelial-Secretory_progenitor|Trachea / Age, Tissue, Lineage and Cell class

CAPN8 VCAN SCARA3 PCDH20

1.25e-04187614be9fce9e74b2f170a2067f1b31d802912a578329
ToppCellMesenchymal-chondrocyte|World / Lineage, Cell type, age group and donor

NPAS3 RFTN2 SIM2 SCARA3

1.28e-041886147b1e3f8a941eaa68e89c562129a92314642eec66
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ZFHX4 VCAN RFTN2 SIM2

1.28e-041886149b95730ddd13eb4624321bab3ab4989414977ca3
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGMA ZFHX4 LRIG1 RFTN2

1.33e-041906145c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGMA ZFHX4 LRIG1 RFTN2

1.39e-04192614f7e4509003d71f805b9d4587098e90d2897b6739
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGMA ZFHX4 LRIG1 RFTN2

1.39e-04192614705ce805cb00a53793b57bcf466d0fbec590a83c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PARP4 ZFHX4 VCAN SCARA3

1.41e-041936140f2167eef8203a5659c8c72e4e77646003d64797
ToppCellHSPCs-Ery_prog.|World / Lineage and Cell class

HK1 PITRM1 POLR1B MUC13

1.41e-04193614484c2e0daedc6cb0d50d164add8c1658123a60f9
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NPM1 ZFHX4 VCAN NPAS3

1.44e-0419461485e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

LRIG1 DNAH10 SPTBN1 ESRRG

1.47e-04195614fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellAdult-Immune-monocyte-D231|Adult / Lineage, Cell type, age group and donor

PIK3AP1 APAF1 LYST PREX1

1.47e-04195614ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 VCAN LYST PREX1

1.47e-0419561410ce1b6961f10372d1f65388cbf3626a5fcd6840
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

LRIG1 DNAH10 SPTBN1 ESRRG

1.47e-04195614eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN8 ZFHX4 ESRRG SIM1

1.50e-04196614c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellCOVID_non-vent-Lymphocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

NPM1 SMG1 FCRL3 SPTBN1

1.53e-04197614c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial|6_mon / Sample Type, Dataset, Time_group, and Cell type.

RGMA LRIG1 NPAS3 SCARA3

1.53e-04197614965d5a3f8c9b12cb8a8d3429702ae29ebd8c6122
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial-Astroglia|6_mon / Sample Type, Dataset, Time_group, and Cell type.

RGMA LRIG1 NPAS3 SCARA3

1.53e-041976143f088eb29197bc575400d6dafd8083e69e4a149f
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon|organoid_Velasco_nature / Sample Type, Dataset, Time_group, and Cell type.

ZFHX4 LRIG1 NPAS3 RFTN2

1.56e-04198614a6f65bb0845d8f64f5c7edb00cee3ca5adb1a373
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Radial_glial-oRG|3_mon / Sample Type, Dataset, Time_group, and Cell type.

ZFHX4 LRIG1 NPAS3 RFTN2

1.56e-0419861472dc49aa107d0cc6206eb67b577c73e190855125
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-IN_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

ZFHX4 LRIG1 NPAS3 RFTN2

1.56e-041986143811d9e3e54bbe8b208c591697e43b55ab5bbf0e
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3AP1 FCRL3 MICAL3 PREX1

1.56e-04198614824461cf44098440ba8bc0df96735423ac65bda1
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CDH22 ZFHX4 NPAS3 MICAL3

1.56e-041986149ab0db78394e730f6866b2db80047149024ad5f6
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3AP1 FCRL3 MICAL3 PREX1

1.56e-04198614863765ccc0205dc28864dae85af339c283194c96
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CDH22 ZFHX4 NPAS3 MICAL3

1.56e-04198614e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Radial_glial-oRG/Astroglia|6_mon / Sample Type, Dataset, Time_group, and Cell type.

RGMA ZFHX4 LRIG1 NPAS3

1.59e-041996140b96fad1be02f0fe7a608207770cc56a6b6b291e
ToppCellLPS_IL1RA_TNF-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PIK3AP1 ATG3 VCAN LYST

1.59e-041996148c2ab13b5fffbab3da37041a7000d6537fc4db09
ToppCellTransverse-T_cell-Tfh|Transverse / Region, Cell class and subclass

CHST10 LRIG1 PELI3 ZNF286B

1.59e-04199614cbef8f95edf2e86e16c448a76068d7ed8f6b7748
ToppCellTransverse-(1)_T_cell-(16)_Tfh|Transverse / shred on region, Cell_type, and subtype

CHST10 LRIG1 PELI3 ZNF286B

1.59e-04199614aa31e26d48066f865ca33251a33a28934c0a7a44
ToppCellTransverse-T_cell-Tfh|T_cell / Region, Cell class and subclass

CHST10 LRIG1 PELI3 ZNF286B

1.59e-0419961433ffea12b8228e0b5bd8942531c3b21d24224725
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Radial_glial|3_mon / Sample Type, Dataset, Time_group, and Cell type.

ZFHX4 LRIG1 NPAS3 RFTN2

1.59e-041996140fee11bd72b27202f8d9fa4daba831ea9c8a61b2
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T|COVID-19_Mild / Disease, condition lineage and cell class

PARP4 LRIG1 SPTBN1 LYST

1.59e-04199614f307d4887b28cf60a591439e278fd668409cb104
ToppCellLPS_IL1RA_TNF-Hematopoietic_Myeloid-Granulocytic_cells|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PIK3AP1 ATG3 VCAN LYST

1.62e-042006141592ca96c59eb053d0f0915afb337db9f3a40c91
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Macroglial-Astrocyte|3m / Sample Type, Dataset, Time_group, and Cell type.

ZFHX4 LRIG1 NPAS3 RFTN2

1.62e-0420061498d7f577b31a603bf835bf9b4ea31999445cf0e5
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial-Astrocyte|GW19 / Sample Type, Dataset, Time_group, and Cell type.

RGMA LRIG1 NPAS3 RFTN2

1.62e-042006147c66953ff6d8f16f4decd23c85232990d2d8c6c4
Diseaseobesity (implicated_via_orthology)

CAPN8 HK1 NT5DC4 ZFHX4 DNAH10 SIM1

4.56e-06215596DOID:9970 (implicated_via_orthology)
Diseaseadiponectin measurement

RGMA DNAH10 MICAL3 HERC2

2.12e-04146594EFO_0004502
Diseaseactinic keratosis

DEF8 HERC2

3.52e-0414592EFO_0002496
Diseaseeye color

HK1 HERC2 SIM2

7.88e-0490593EFO_0003949
DiseaseAtaxia

HK1 PITRM1

1.14e-0325592C0004134
Diseasepseudotumor cerebri

RGMA PARP4

1.24e-0326592EFO_1001132

Protein segments in the cluster

PeptideGeneStartEntry
SMTGELVHTYDEHSE

APAF1

686

O14727
HDESMTYEDRSQLDH

VCAN

2651

P13611
SVDDMHDKGYTDQDL

ABCD2

566

Q9UBJ2
YQRIHHEESEMETEE

ANKRD13C

301

Q8N6S4
ETDYNHSGTIDAHEM

CAPN8

616

A6NHC0
HGEEADAVYESMAHL

PIK3AP1

411

Q6ZUJ8
PLTVEHMYEDISQDH

ATG3

226

Q9NT62
ELHIVEAEAMNYEGS

NPM1

56

P06748
SHYEEEHSGEDRDVK

RBSN

31

Q9H1K0
IEEELHHESGQYQME

RFTN2

211

Q52LD8
ELDHEESGFYQMEVQ

PCDHGA12

306

O60330
DYHGMFTLDVEENEN

PCDH20

251

Q8N6Y1
HLYDTGETKDIHLEM

MICAL3

486

Q7RTP6
VHVHAQDGEVMEYTT

LRIG1

546

Q96JA1
DSENMDVLHESHDIF

HERC2

3911

O95714
DQHYTVDMTETEHSI

HMGXB3

1146

Q12766
ETEAVNYHDETGEIM

NUDT9

281

Q9BW91
DYLHMVHRLSSDDGD

NIPBL

246

Q6KC79
HYVIQPHDDTEDSMN

NFYB

26

P25208
LFSHEHMGSEQYDAD

KIF24

1161

Q5T7B8
NREEMELEHSDSGYE

LCA5L

561

O95447
YEDGILHENETSHEM

PARP4

1136

Q9UKK3
HMESEVYDTPENIVH

HK1

106

P19367
LDTHLADIYQHMDGS

NT5DC4

361

Q86YG4
QEDLEITHMYSAEGE

DNAH1

1366

Q9P2D7
YHRETEGEEAGMFSH

KCNA7

401

Q96RP8
HEALQDYEAGQHMED

ESRRG

396

P62508
EEEEEETHMATLGQY

LYST

31

Q99698
METQIHLYGHTEEIT

LYST

3606

Q99698
MHQEHEELTVLYSEL

FCRL3

681

Q96P31
DEMYSVQDLLDVHAG

DEF8

406

Q6ZN54
AEDSDVGENTDMTYH

CDH22

301

Q9UJ99
SAKEELYNLHEEMEH

DNAH10

1076

Q8IVF4
SFLDDHEENMHDLQY

SCARA3

316

Q6AZY7
GDENYMEFLEVLTEH

SLC12A5

1106

Q9H2X9
TDEDEHSIEMHLPYT

MEMO1

126

Q9Y316
VTYEMDHGEAHVQTD

TMEM67

511

Q5HYA8
SMEEDHGSLYLDNLE

TMEM225B

186

P0DP42
EEILHQEGHSMGVYD

PRPF4

356

O43172
HSVIVEYTHDSDTDM

PELI3

136

Q8N2H9
MGLEEETHAHYIDVA

SMG1

2916

Q96Q15
HVLPDDSHMDTYEQG

PITRM1

651

Q5JRX3
MEVENVEDGTADYHS

PREX1

336

Q8TCU6
EYIHPSDHDEMTAVL

SIM2

126

Q14190
EYIHPADHDEMTAVL

SIM1

126

P81133
DDFIQEMEHGIYTDV

TAP2

586

Q03519
DYVHPGDHVEMAEQL

NPAS3

196

Q8IXF0
DLAYHSAVHGIEDLM

RGMA

96

Q96B86
AGSHELGQDYEHVTM

SPTBN1

1721

Q01082
MYSVIGHHETLEDDA

CHST10

276

O43529
EGMDVHATYDEHQVT

ZBTB43

256

O43298
EDTHYDKVEDVVGSH

STK31

26

Q9BXU1
HGLEQEMEREYEVDH

ZFHX4

1436

Q86UP3
EEKHSMAYQDLHSEI

MUC13

231

Q9H3R2
HHYESFQDDEGASML

FAM20B

291

O75063
MNSLSEETDHEHDVY

ZNF286B

181

P0CG31
EGDEEMELAHVEHYA

PTGES3L

121

E9PB15
LIEHHEEAEEMGGYF

POLR1B

156

Q9H9Y6
EYHNAMVVGTEEAED

ZGPAT

146

Q8N5A5
DIEADILHYSGHGMD

TMPPE

336

Q6ZT21
HLIINEAMLEDAGHY

MYBPC3

511

Q14896
LFHSCQMVEESHEEE

MYSM1

356

Q5VVJ2