Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

THBS2 FBN1 FBN2 VWF LAMC1 LTBP2 MUC2 MUC5AC AGRN FBN3

2.16e-101886010GO:0005201
GeneOntologyMolecularFunctioncalcium ion binding

THBS2 SCUBE1 FBN1 FBN2 SULF1 LRP1 LTBP2 VWCE AGRN TENM2 FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

4.19e-107496016GO:0005509
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

FBN1 FBN2 LAMC1

5.57e-0612603GO:0030023
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

FBN1 FBN2 LAMC1

9.17e-0614603GO:0097493
GeneOntologyMolecularFunctionstructural molecule activity

THBS2 FBN1 FBN2 VWF LAMC1 LTBP2 MUC2 MUC5AC AGRN FBN3

2.95e-048916010GO:0005198
GeneOntologyMolecularFunctionglycosaminoglycan binding

THBS2 FBN1 SULF1 LTBP2 AGRN

1.25e-03268605GO:0005539
GeneOntologyMolecularFunctionchromatin DNA binding

ATRX PER1 KDM4E NOTCH1

1.60e-03167604GO:0031490
GeneOntologyMolecularFunctionmethylated histone binding

ATRX DPF2 KMT2E

2.21e-0386603GO:0035064
GeneOntologyMolecularFunctionmethylation-dependent protein binding

ATRX DPF2 KMT2E

2.36e-0388603GO:0140034
GeneOntologyMolecularFunctionsulfur compound binding

THBS2 FBN1 LRP1 LTBP2 AGRN

2.83e-03323605GO:1901681
GeneOntologyMolecularFunctionNotch binding

NOTCH1 NOTCH4

2.97e-0327602GO:0005112
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

LRP1 AGRN

3.42e-0329602GO:0043395
GeneOntologyBiologicalProcesspositive regulation of BMP signaling pathway

SULF1 NOTCH1 NOTCH2 CRB2

6.23e-0642594GO:0030513
GeneOntologyBiologicalProcesskidney development

MPST FBN1 SULF1 WNT4 SIM1 NOTCH1 NOTCH2 NOTCH3

1.03e-05372598GO:0001822
GeneOntologyBiologicalProcessrenal system development

MPST FBN1 SULF1 WNT4 SIM1 NOTCH1 NOTCH2 NOTCH3

1.35e-05386598GO:0072001
GeneOntologyBiologicalProcessaxon guidance

LRP1 LAMC1 AGRN TENM2 NOTCH1 NOTCH2 NOTCH3

1.65e-05285597GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

LRP1 LAMC1 AGRN TENM2 NOTCH1 NOTCH2 NOTCH3

1.69e-05286597GO:0097485
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

FBN1 FBN2 SULF1 LRP1 WNT4 NOTCH1 NOTCH2 CRB2

2.15e-05412598GO:0090287
GeneOntologyBiologicalProcesscellular response to tumor cell

NOTCH1 NOTCH2

2.41e-053592GO:0071228
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

FBN1 SULF1 NOTCH1 NOTCH2 CRB2

3.64e-05131595GO:0030510
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

FBN1 FBN2 SULF1 LRP1 LTBP2 NOTCH1 NOTCH2 CRB2

3.73e-05445598GO:0141091
GeneOntologyBiologicalProcesspositive regulation of aorta morphogenesis

NOTCH1 NOTCH4

4.81e-054592GO:1903849
GeneOntologyBiologicalProcesssequestering of TGFbeta in extracellular matrix

FBN1 FBN2

4.81e-054592GO:0035583
GeneOntologyBiologicalProcesscell fate commitment

TENM4 WNT4 MGA NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.90e-05338597GO:0045165
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

FBN1 FBN2 SULF1 LRP1 NOTCH1 NOTCH2 CRB2

5.78e-05347597GO:0090092
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

FBN1 FBN2 SULF1 LRP1 LTBP2 NOTCH1 NOTCH2 CRB2

6.54e-05482598GO:0007178
GeneOntologyBiologicalProcesspositive regulation of smooth muscle cell differentiation

NOTCH1 NOTCH2 NOTCH4

6.92e-0528593GO:0051152
GeneOntologyBiologicalProcessglomerulus development

SULF1 NOTCH1 NOTCH2 NOTCH3

6.99e-0577594GO:0032835
GeneOntologyBiologicalProcessglomerulus vasculature development

NOTCH1 NOTCH2 NOTCH3

8.54e-0530593GO:0072012
GeneOntologyBiologicalProcesskidney vasculature development

NOTCH1 NOTCH2 NOTCH3

9.44e-0531593GO:0061440
GeneOntologyBiologicalProcessrenal system vasculature development

NOTCH1 NOTCH2 NOTCH3

9.44e-0531593GO:0061437
GeneOntologyBiologicalProcessglomerulus vasculature morphogenesis

NOTCH2 NOTCH3

1.20e-046592GO:0072103
GeneOntologyBiologicalProcessglomerular capillary formation

NOTCH2 NOTCH3

1.20e-046592GO:0072104
GeneOntologyBiologicalProcessregulation of aorta morphogenesis

NOTCH1 NOTCH4

1.20e-046592GO:1903847
GeneOntologyBiologicalProcessnephron development

SULF1 WNT4 NOTCH1 NOTCH2 NOTCH3

1.40e-04174595GO:0072006
GeneOntologyBiologicalProcessartery morphogenesis

LRP1 NOTCH1 NOTCH3 NOTCH4

1.40e-0492594GO:0048844
GeneOntologyBiologicalProcessrenal system vasculature morphogenesis

NOTCH2 NOTCH3

1.67e-047592GO:0061438
GeneOntologyBiologicalProcesskidney vasculature morphogenesis

NOTCH2 NOTCH3

1.67e-047592GO:0061439
GeneOntologyBiologicalProcesspositive regulation of transcription of Notch receptor target

NOTCH1 NOTCH4

1.67e-047592GO:0007221
GeneOntologyBiologicalProcessregulation of embryonic development

TENM4 WNT4 NOTCH1 CRB2

1.86e-0499594GO:0045995
GeneOntologyBiologicalProcesssmooth muscle cell differentiation

WNT4 NOTCH1 NOTCH2 NOTCH4

1.86e-0499594GO:0051145
GeneOntologyBiologicalProcessaorta morphogenesis

LRP1 NOTCH1 NOTCH4

2.19e-0441593GO:0035909
GeneOntologyBiologicalProcessmaintenance of protein location in extracellular region

FBN1 FBN2

2.23e-048592GO:0071694
GeneOntologyBiologicalProcesspositive regulation of muscle cell differentiation

LAMC1 NOTCH1 NOTCH2 NOTCH4

2.41e-04106594GO:0051149
GeneOntologyBiologicalProcessBMP signaling pathway

FBN1 SULF1 NOTCH1 NOTCH2 CRB2

2.49e-04197595GO:0030509
GeneOntologyBiologicalProcessatrioventricular node development

NOTCH1 NOTCH2

2.86e-049592GO:0003162
GeneOntologyBiologicalProcesspositive regulation of artery morphogenesis

NOTCH1 NOTCH4

2.86e-049592GO:1905653
GeneOntologyBiologicalProcesspositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

SULF1 NOTCH1 NOTCH2 CRB2

3.29e-04115594GO:0090100
GeneOntologyBiologicalProcessnegative regulation of cell-cell adhesion mediated by cadherin

NOTCH1 NOTCH4

3.57e-0410592GO:2000048
GeneOntologyBiologicalProcesspericyte cell differentiation

WNT4 NOTCH1

3.57e-0410592GO:1904238
GeneOntologyBiologicalProcessresponse to BMP

FBN1 SULF1 NOTCH1 NOTCH2 CRB2

3.72e-04215595GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

FBN1 SULF1 NOTCH1 NOTCH2 CRB2

3.72e-04215595GO:0071773
GeneOntologyBiologicalProcessglomerulus morphogenesis

NOTCH2 NOTCH3

4.35e-0411592GO:0072102
GeneOntologyBiologicalProcesssequestering of extracellular ligand from receptor

FBN1 FBN2

4.35e-0411592GO:0035581
GeneOntologyBiologicalProcessaxon development

LRP1 MTR LAMC1 AGRN TENM2 NOTCH1 NOTCH2 NOTCH3

4.61e-04642598GO:0061564
GeneOntologyBiologicalProcessregulation of smooth muscle cell differentiation

NOTCH1 NOTCH2 NOTCH4

4.97e-0454593GO:0051150
GeneOntologyBiologicalProcessresponse to wounding

SCUBE1 VWF HPS4 LRP1 MTR WNT4 NOTCH2 NOTCH4

5.48e-04659598GO:0009611
GeneOntologyBiologicalProcessartery development

LRP1 NOTCH1 NOTCH3 NOTCH4

5.71e-04133594GO:0060840
GeneOntologyBiologicalProcesscell differentiation involved in kidney development

WNT4 NOTCH1 NOTCH2

5.83e-0457593GO:0061005
GeneOntologyBiologicalProcessvenous blood vessel morphogenesis

NOTCH1 NOTCH4

6.15e-0413592GO:0048845
GeneOntologyBiologicalProcessregulation of osteoclast development

FBN1 NOTCH2

6.15e-0413592GO:2001204
GeneOntologyBiologicalProcessextracellular regulation of signal transduction

FBN1 FBN2

6.15e-0413592GO:1900115
GeneOntologyBiologicalProcessextracellular negative regulation of signal transduction

FBN1 FBN2

6.15e-0413592GO:1900116
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

FBN1 FBN2 SULF1 LRP1 LTBP2 WNT4 NOTCH1 NOTCH2 CRB2

6.49e-04850599GO:0071363
GeneOntologyBiologicalProcesscirculatory system development

THBS2 SCUBE1 FBN1 TENM4 SULF1 LRP1 WNT4 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

6.73e-0414425912GO:0072359
GeneOntologyBiologicalProcessnegative regulation of hematopoietic progenitor cell differentiation

DPF2 NOTCH1

7.16e-0414592GO:1901533
GeneOntologyBiologicalProcessleft/right axis specification

NOTCH1 NOTCH2

7.16e-0414592GO:0070986
GeneOntologyBiologicalProcessheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

TENM4 TENM2 CRB2

7.81e-0463593GO:0007157
GeneOntologyBiologicalProcesshomocysteine metabolic process

MPST MTR

8.25e-0415592GO:0050667
GeneOntologyBiologicalProcesspositive regulation of chemokine (C-X-C motif) ligand 2 production

MIF LRP1

8.25e-0415592GO:2000343
GeneOntologyBiologicalProcessresponse to growth factor

FBN1 FBN2 SULF1 LRP1 LTBP2 WNT4 NOTCH1 NOTCH2 CRB2

8.51e-04883599GO:0070848
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

FBN1 SULF1 WNT4 NOTCH1

8.96e-04150594GO:0090288
GeneOntologyBiologicalProcessneuroendocrine cell differentiation

WNT4 NOTCH1

9.41e-0416592GO:0061101
GeneOntologyBiologicalProcessnegative regulation of cell adhesion molecule production

NOTCH1 NOTCH4

9.41e-0416592GO:0060354
GeneOntologyBiologicalProcessepithelial cell development

ATRX MUC2 NOTCH1 NOTCH2 NOTCH4

1.02e-03269595GO:0002064
GeneOntologyBiologicalProcessgland development

MPST VWF SULF1 WNT4 NOTCH1 NOTCH2 NOTCH4

1.03e-03558597GO:0048732
GeneOntologyBiologicalProcessregulation of artery morphogenesis

NOTCH1 NOTCH4

1.06e-0317592GO:1905651
GeneOntologyBiologicalProcessregulation of postsynaptic neurotransmitter receptor activity

NRXN2 NOTCH1

1.06e-0317592GO:0098962
GeneOntologyBiologicalProcessaxonogenesis

LRP1 LAMC1 AGRN TENM2 NOTCH1 NOTCH2 NOTCH3

1.12e-03566597GO:0007409
GeneOntologyBiologicalProcesscell junction assembly

THBS2 NRXN2 LRP1 LAMC1 WNT4 CSMD2 AGRN

1.15e-03569597GO:0034329
GeneOntologyBiologicalProcesskidney epithelium development

WNT4 SIM1 NOTCH1 NOTCH2

1.19e-03162594GO:0072073
GeneOntologyBiologicalProcesspositive regulation of nervous system development

THBS2 TENM4 LRP1 AGRN NOTCH1 NOTCH2

1.22e-03418596GO:0051962
GeneOntologyBiologicalProcessnegative regulation of cell migration

SULF1 MIF LRP1 WNT4 MUC2 NOTCH1

1.23e-03419596GO:0030336
GeneOntologyBiologicalProcesspulmonary valve morphogenesis

NOTCH1 NOTCH2

1.48e-0320592GO:0003184
GeneOntologyBiologicalProcessregulation of gastrulation

TENM4 CRB2

1.48e-0320592GO:0010470
GeneOntologyBiologicalProcessvenous blood vessel development

NOTCH1 NOTCH4

1.48e-0320592GO:0060841
GeneOntologyBiologicalProcessnegative regulation of cell motility

SULF1 MIF LRP1 WNT4 MUC2 NOTCH1

1.49e-03435596GO:2000146
GeneOntologyBiologicalProcessaorta development

LRP1 NOTCH1 NOTCH4

1.56e-0380593GO:0035904
GeneOntologyBiologicalProcessregulation of cell-cell adhesion mediated by cadherin

NOTCH1 NOTCH4

1.63e-0321592GO:2000047
GeneOntologyBiologicalProcessgland morphogenesis

SULF1 WNT4 NOTCH1 NOTCH2

1.69e-03178594GO:0022612
GeneOntologyBiologicalProcesscell junction organization

THBS2 TENM4 NRXN2 LRP1 LAMC1 CHAT WNT4 CSMD2 AGRN

1.69e-03974599GO:0034330
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

ATRX MYT1 PER1 KAT6B MGA ST18 AGRN NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.74e-0313905911GO:0045944
GeneOntologyBiologicalProcessosteoclast development

FBN1 NOTCH2

1.79e-0322592GO:0036035
GeneOntologyBiologicalProcessbone cell development

FBN1 NOTCH2

1.79e-0322592GO:0098751
GeneOntologyBiologicalProcessretinal cone cell differentiation

NOTCH1 CRB2

1.79e-0322592GO:0042670
GeneOntologyBiologicalProcessregulation of extracellular matrix organization

LRP1 LAMC1 NOTCH1

1.80e-0384593GO:1903053
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

FBN1 FBN2 SULF1 LRP1 LTBP2 WNT4 AGRN NOTCH1 NOTCH2 CRB2

1.82e-0311865910GO:0007167
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

NFX1 PER1 DPF2 WNT4 KAT6B ST18 TENM2 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.84e-0313995911GO:0045892
GeneOntologyBiologicalProcessnegative regulation of locomotion

SULF1 MIF LRP1 WNT4 MUC2 NOTCH1

1.85e-03454596GO:0040013
GeneOntologyBiologicalProcesstube development

THBS2 FBN1 ATRX SULF1 LRP1 WNT4 SIM1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.87e-0314025911GO:0035295
GeneOntologyBiologicalProcessregulation of cell junction assembly

THBS2 NRXN2 LRP1 WNT4 AGRN

1.89e-03309595GO:1901888
GeneOntologyBiologicalProcessappendage morphogenesis

FBN2 ATRX NOTCH1 NOTCH2

1.94e-03185594GO:0035107
GeneOntologyBiologicalProcesslimb morphogenesis

FBN2 ATRX NOTCH1 NOTCH2

1.94e-03185594GO:0035108
GeneOntologyBiologicalProcessregulation of cell adhesion molecule production

NOTCH1 NOTCH4

1.96e-0323592GO:0060353
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

NFX1 PER1 DPF2 WNT4 KAT6B ST18 TENM2 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.99e-0314135911GO:1902679
GeneOntologyBiologicalProcesschemokine (C-X-C motif) ligand 2 production

MIF LRP1

2.13e-0324592GO:0072567
GeneOntologyBiologicalProcesspulmonary valve development

NOTCH1 NOTCH2

2.13e-0324592GO:0003177
GeneOntologyBiologicalProcessregulation of chemokine (C-X-C motif) ligand 2 production

MIF LRP1

2.13e-0324592GO:2000341
GeneOntologyBiologicalProcessblood vessel morphogenesis

THBS2 SULF1 LRP1 WNT4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.17e-03817598GO:0048514
GeneOntologyBiologicalProcessglandular epithelial cell differentiation

WNT4 MUC2 NOTCH1

2.26e-0391593GO:0002067
GeneOntologyBiologicalProcesspositive regulation of Ras protein signal transduction

NOTCH1 NOTCH2

2.31e-0325592GO:0046579
GeneOntologyBiologicalProcesspositive regulation of small GTPase mediated signal transduction

AGRN NOTCH1 NOTCH2

2.33e-0392593GO:0051057
GeneOntologyCellularComponentextracellular matrix

LAMB4 THBS2 FBN1 FCGBP FBN2 VWF SULF1 LAMC1 LTBP2 WNT4 MUC2 MUC5AC AGRN FBN3

3.58e-096566014GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMB4 THBS2 FBN1 FCGBP FBN2 VWF SULF1 LAMC1 LTBP2 WNT4 MUC2 MUC5AC AGRN FBN3

3.72e-096586014GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMB4 THBS2 FBN1 FBN2 VWF SULF1 LAMC1 LTBP2 MUC2 AGRN

2.44e-065306010GO:0062023
GeneOntologyCellularComponentmicrofibril

FBN1 FBN2 FBN3

6.30e-0613603GO:0001527
GeneOntologyCellularComponentmucus layer

MUC2 MUC5AC

2.43e-053602GO:0070701
GeneOntologyCellularComponentbasement membrane

LAMB4 THBS2 FBN1 LAMC1 AGRN

2.63e-05122605GO:0005604
GeneOntologyCellularComponentcell surface

SCUBE1 VWF SULF1 MIF LRP1 WNT4 AGRN VWDE NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.26e-0511116012GO:0009986
GeneOntologyCellularComponentGolgi lumen

WNT4 MUC2 MUC5AC AGRN

2.72e-04109604GO:0005796
GeneOntologyCellularComponentglutamatergic synapse

TENM4 NRXN2 LRP1 ADGRA1 CSMD2 AGRN TENM2 NOTCH1

2.23e-03817608GO:0098978
HumanPhenoVentricular septal defect

FBN1 FBN2 ATRX LTBP2 DPF2 WNT4 KAT6B NOTCH1 NOTCH2 NOTCH3 CRB2

4.02e-065102311HP:0001629
HumanPhenoAbnormal ventricular septum morphology

FBN1 FBN2 ATRX LTBP2 DPF2 WNT4 KAT6B NOTCH1 NOTCH2 NOTCH3 CRB2

4.97e-065212311HP:0010438
HumanPhenoAbnormal heart valve morphology

FBN1 FBN2 VWF ATRX LTBP2 DPF2 WNT4 KAT6B NOTCH1 NOTCH2 NOTCH3

1.62e-055882311HP:0001654
HumanPhenoAbnormal aortic valve morphology

FBN1 FBN2 VWF LTBP2 DPF2 NOTCH1 NOTCH2 NOTCH3

2.26e-05289238HP:0001646
HumanPhenoAbnormality of the forehead

FBN1 FBN2 ATRX GNE LRP1 CHAT DPF2 WNT4 SIM1 KMT2E KAT6B TSEN2 AGRN NOTCH2 NOTCH3

2.67e-0512082315HP:0000290
HumanPhenoAbnormal upper to lower segment ratio

FBN1 FBN2

5.84e-053232HP:0012772
HumanPhenoWeak cry

ATRX CHAT SIM1 AGRN

5.85e-0549234HP:0001612
HumanPhenoAbnormal atrioventricular valve morphology

FBN1 FBN2 VWF ATRX LTBP2 KAT6B NOTCH1 NOTCH2

9.00e-05350238HP:0006705
HumanPhenoMicrospherophakia

FBN1 LTBP2

1.16e-044232HP:0030961
HumanPhenoAortic valve stenosis

FBN1 VWF LTBP2 NOTCH1 NOTCH2

1.20e-04113235HP:0001650
HumanPhenoNeuropathic spinal arthropathy

GNE CHAT AGRN

1.34e-0423233HP:0008443
HumanPhenoApnea

FBN1 GNE CHAT SIM1 KAT6B TSEN2 AGRN NOTCH3

1.39e-04372238HP:0002104
HumanPhenoAbnormal cry

ATRX CHAT SIM1 AGRN

1.39e-0461234HP:0025429
HumanPhenoBicuspid aortic valve

FBN1 FBN2 DPF2 NOTCH1 NOTCH3

1.54e-04119235HP:0001647
HumanPhenoAbnormal aortic valve cusp morphology

FBN1 FBN2 DPF2 NOTCH1 NOTCH3

1.66e-04121235HP:0031567
HumanPhenoKyphoscoliosis

FBN1 FBN2 ATRX CHAT AGRN NOTCH2

1.75e-04196236HP:0002751
HumanPhenoAbnormal pulmonary valve morphology

FBN1 ATRX LTBP2 WNT4 NOTCH1 NOTCH2

1.85e-04198236HP:0001641
HumanPhenoLow-set ears

FBN1 ATRX GNE CHAT DPF2 WNT4 SIM1 KAT6B AGRN NOTCH2 NOTCH3

1.86e-047612311HP:0000369
HumanPhenoIridodonesis

FBN1 LTBP2

1.93e-045232HP:0100693
HumanPhenoSpherophakia

FBN1 LTBP2

1.93e-045232HP:0034375
HumanPhenoAbnormal cardiac ventricle morphology

FBN1 FBN2 ATRX LTBP2 DPF2 WNT4 KAT6B NOTCH1 NOTCH2 NOTCH3 CRB2

2.33e-047802311HP:0001713
HumanPhenoAbnormal heart valve physiology

FBN1 FBN2 VWF ATRX LTBP2 WNT4 NOTCH1 NOTCH2

2.43e-04403238HP:0031653
HumanPhenoMitral stenosis

FBN1 NOTCH1 NOTCH2

2.45e-0428233HP:0001718
HumanPhenoAbnormal cardiac septum morphology

FBN1 FBN2 ATRX LTBP2 DPF2 WNT4 KAT6B NOTCH1 NOTCH2 NOTCH3 CRB2

2.53e-047872311HP:0001671
HumanPhenoCrumpled ear

FBN1 FBN2

2.89e-046232HP:0009901
HumanPhenoAbnormal atrioventricular valve physiology

FBN1 FBN2 ATRX LTBP2 NOTCH1 NOTCH2

2.91e-04215236HP:0031650
HumanPhenoAbnormality of the upper respiratory tract

FBN1 FBN2 ATRX GNE MIF CHAT DPF2 SIM1 KAT6B TSEN2 AGRN NOTCH2 NOTCH3

2.95e-0411112313HP:0002087
HumanPhenoPulmonic stenosis

FBN1 LTBP2 WNT4 NOTCH1 NOTCH2

3.08e-04138235HP:0001642
HumanPhenoDolichocephaly

FBN1 FBN2 ATRX KMT2E NOTCH2 NOTCH3

3.22e-04219236HP:0000268
HumanPhenoCentral sleep apnea

CHAT SIM1 AGRN

3.33e-0431233HP:0010536
HumanPhenoObstructive sleep apnea

CHAT SIM1 AGRN NOTCH3

3.79e-0479234HP:0002870
HumanPhenoCongenital hip dislocation

LRP1 CHAT KAT6B AGRN

4.80e-0484234HP:0001374
HumanPhenoPoor suck

ATRX CHAT SIM1 TSEN2 AGRN

4.82e-04152235HP:0002033
HumanPhenoAbsent frontal sinuses

ATRX NOTCH2

5.37e-048232HP:0002688
HumanPhenoMenorrhagia

VWF GNE HPS4

6.12e-0438233HP:0000132
HumanPhenoAbnormal pulmonary valve physiology

FBN1 LTBP2 WNT4 NOTCH1 NOTCH2

6.65e-04163235HP:0031654
HumanPhenoAbnormal sternum morphology

FBN1 FBN2 CHAT LTBP2 DPF2 AGRN NOTCH2 NOTCH3

7.37e-04474238HP:0000766
HumanPhenoAbnormal mitral valve morphology

FBN1 FBN2 VWF LTBP2 NOTCH1 NOTCH2

7.59e-04257236HP:0001633
HumanPhenoSleep apnea

GNE CHAT SIM1 AGRN NOTCH3

7.63e-04168235HP:0010535
HumanPhenoSleep-related breathing disorders

GNE CHAT SIM1 AGRN NOTCH3

7.84e-04169235HP:5200283
HumanPhenoFrontalis muscle weakness

CHAT AGRN

8.59e-0410232HP:0004661
HumanPhenoMalrotation of small bowel

WNT4 KAT6B

8.59e-0410232HP:0004794
HumanPhenoAbnormal frontalis muscle physiology

CHAT AGRN

8.59e-0410232HP:3000004
HumanPhenoAbnormality of occipitofrontalis muscle

CHAT AGRN

8.59e-0410232HP:0040172
HumanPhenoLens dislocation

FBN1 FBN2 LTBP2

8.82e-0443233HP:0000665
HumanPhenoEctopia lentis

FBN1 FBN2 LTBP2

8.82e-0443233HP:0001083
HumanPhenoPectus carinatum

FBN1 FBN2 CHAT AGRN NOTCH2

9.92e-04178235HP:0000768
HumanPhenoBruising susceptibility

FBN1 VWF ATRX GNE HPS4

9.92e-04178235HP:0000978
HumanPhenoAbnormal mitral valve physiology

FBN1 FBN2 LTBP2 NOTCH1 NOTCH2

1.04e-03180235HP:0031481
HumanPhenoAbnormality of the amniotic fluid

FBN1 CHAT DPF2 WNT4 KAT6B TSEN2 AGRN CRB2

1.11e-03504238HP:0001560
HumanPhenoChiari malformation

FBN1 DPF2 NOTCH2 NOTCH3

1.20e-03107234HP:0002308
HumanPhenoKyphosis

FBN1 FBN2 ATRX CHAT KMT2E AGRN NOTCH2 NOTCH3

1.20e-03510238HP:0002808
HumanPhenoJoint dislocation

FBN1 FBN2 LRP1 CHAT KAT6B AGRN NOTCH2

1.22e-03390237HP:0001373
HumanPhenoAbnormal cheek morphology

FBN1 LRP1 SIM1 KMT2E KAT6B NOTCH2

1.24e-03282236HP:0004426
HumanPhenoApneic episodes precipitated by illness, fatigue, stress

CHAT AGRN

1.25e-0312232HP:0002872
HumanPhenoSkin-picking

SIM1 KMT2E

1.25e-0312232HP:0012166
MousePhenoskeletal muscle atrophy

LAMC1 CHAT AGRN NOTCH3

3.41e-0554484MP:0009417
MousePhenoabnormal vertebral column morphology

THBS2 FBN1 FBN2 TENM4 SULF1 CHAT ZC2HC1C ST18 NOTCH1 NOTCH2 NOTCH3

5.57e-057874811MP:0004703
MousePhenokidney microaneurysm

LAMC1 NOTCH2

1.15e-045482MP:0010451
MousePhenoabnormal hypaxial muscle morphology

FBN1 MYT1 LRP1 LAMC1 CHAT

1.17e-04141485MP:0003358
MousePhenodiaphragmatic hernia

FBN1 LRP1 CHAT

1.30e-0429483MP:0003924
MousePhenoabnormal diaphragm morphology

FBN1 MYT1 LRP1 CHAT

1.45e-0478484MP:0002279
MousePhenoabnormal skeletal muscle mass

FBN2 LAMC1 CHAT AGRN NOTCH3

1.52e-04149485MP:0004817
MousePhenoabnormal blood coagulation

THBS2 SCUBE1 FBN1 VWF HPS4 NOTCH3

1.61e-04240486MP:0002551
MousePhenodecreased skeletal muscle size

LAMC1 CHAT AGRN NOTCH3

1.68e-0481484MP:0010240
MousePhenoabnormal hemostasis

THBS2 SCUBE1 FBN1 VWF HPS4 NOTCH3

1.69e-04242486MP:0009676
MousePhenoaneurysm

FBN1 LAMC1 NOTCH2

2.30e-0435483MP:0003279
MousePhenoincreased bleeding time

THBS2 SCUBE1 VWF HPS4

2.63e-0491484MP:0005606
MousePhenoabnormal axial skeleton morphology

THBS2 SCUBE1 FBN1 FBN2 TENM4 SULF1 CHAT ZC2HC1C KAT6B ST18 VWDE NOTCH1 NOTCH2 NOTCH3

2.68e-0414584814MP:0002114
MousePhenoabnormal muscle morphology

THBS2 FBN1 FBN2 MYT1 LRP1 LAMC1 CHAT KAT6B AGRN NOTCH1 NOTCH2 NOTCH3

2.72e-0411064812MP:0002108
MousePhenoabnormal skeletal muscle size

LAMC1 CHAT AGRN NOTCH3

2.86e-0493484MP:0009458
MousePhenoincreased osteoblast cell number

PER1 NOTCH2 NOTCH3

2.95e-0438483MP:0004988
MousePhenoabnormal skeletal muscle morphology

FBN1 FBN2 MYT1 LRP1 LAMC1 CHAT AGRN NOTCH3

3.01e-04508488MP:0000759
MousePhenomuscular atrophy

LAMC1 CHAT AGRN NOTCH3

3.22e-0496484MP:0002269
MousePhenoabnormal thrombosis

SCUBE1 FBN1 VWF NOTCH3

4.70e-04106484MP:0005048
MousePhenokidney failure

GNE LAMC1 WNT4

5.20e-0446483MP:0003606
MousePhenoperinatal lethality, complete penetrance

SCUBE1 MYT1 LRP1 LAMC1 CHAT WNT4 SIM1 AGRN NOTCH2

6.15e-04712489MP:0011089
DomainEGF

THBS2 SCUBE1 FBN1 FCGBP FBN2 TENM4 NRXN2 LRP1 LAMC1 LTBP2 VWCE AGRN TENM2 VWDE FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

1.72e-232356120SM00181
DomainEGF-like_dom

THBS2 SCUBE1 FBN1 FCGBP FBN2 TENM4 NRXN2 LRP1 LAMC1 LTBP2 VWCE AGRN TENM2 VWDE FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

5.59e-232496120IPR000742
DomainEGF_1

LAMB4 THBS2 SCUBE1 FBN1 FBN2 TENM4 NRXN2 LRP1 LAMC1 LTBP2 VWCE AGRN TENM2 VWDE FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

9.05e-232556120PS00022
DomainEGF-like_CS

LAMB4 THBS2 SCUBE1 FBN1 FBN2 TENM4 NRXN2 LRP1 LAMC1 LTBP2 VWCE AGRN TENM2 VWDE FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

1.45e-222616120IPR013032
DomainEGF_2

LAMB4 THBS2 SCUBE1 FBN1 FBN2 TENM4 NRXN2 LRP1 LAMC1 LTBP2 VWCE AGRN TENM2 VWDE FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

1.97e-222656120PS01186
DomainEGF_3

THBS2 SCUBE1 FBN1 FBN2 TENM4 NRXN2 LRP1 LTBP2 VWCE AGRN TENM2 VWDE FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

2.63e-202356118PS50026
DomainEGF_CA

THBS2 SCUBE1 FBN1 FBN2 LRP1 LTBP2 VWCE AGRN TENM2 FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

3.80e-201226115SM00179
DomainEGF-like_Ca-bd_dom

THBS2 SCUBE1 FBN1 FBN2 LRP1 LTBP2 VWCE AGRN TENM2 FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

4.90e-201246115IPR001881
DomainEGF_CA

THBS2 SCUBE1 FBN1 FBN2 LRP1 LTBP2 VWCE FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.94e-17866112PF07645
DomainEGF_Ca-bd_CS

SCUBE1 FBN1 FBN2 LRP1 LTBP2 VWCE FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

2.69e-16976112IPR018097
DomainEGF_CA

SCUBE1 FBN1 FBN2 LRP1 LTBP2 VWCE FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

3.48e-16996112PS01187
DomainASX_HYDROXYL

SCUBE1 FBN1 FBN2 LRP1 LTBP2 VWCE FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

3.94e-161006112PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

SCUBE1 FBN1 FBN2 LRP1 LTBP2 VWCE FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

8.14e-161066112IPR000152
DomainGrowth_fac_rcpt_

SCUBE1 FBN1 FBN2 LRP1 LAMC1 LTBP2 VWCE FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.20e-141566112IPR009030
DomainEGF

THBS2 NRXN2 LRP1 LTBP2 AGRN FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

2.66e-131266111PF00008
DomainhEGF

FBN2 FBN3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 CRB2

3.12e-1228617PF12661
DomainNotch

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.03e-104614IPR008297
DomainNODP

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.03e-104614PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.03e-104614IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.03e-104614IPR010660
DomainNOD

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.03e-104614PF06816
DomainNOD

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.03e-104614SM01338
DomainNODP

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.03e-104614SM01339
DomainLNR

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.14e-105614PS50258
DomainVWD

FCGBP VWF MUC2 MUC5AC VWDE

1.34e-0916615SM00216
DomainVWF_type-D

FCGBP VWF MUC2 MUC5AC VWDE

1.34e-0916615IPR001846
DomainVWFD

FCGBP VWF MUC2 MUC5AC VWDE

1.34e-0916615PS51233
DomainVWD

FCGBP VWF MUC2 MUC5AC VWDE

1.34e-0916615PF00094
DomainVWC

THBS2 FCGBP VWF VWCE MUC2 MUC5AC

2.40e-0938616SM00214
DomainVWC_out

FCGBP VWF VWCE MUC2 MUC5AC

3.53e-0919615SM00215
DomainTB

FBN1 FBN2 LTBP2 FBN3

3.58e-097614PF00683
DomainNotch_dom

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.58e-097614IPR000800
DomainNotch

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.58e-097614PF00066
DomainNL

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.58e-097614SM00004
DomainVWF_dom

THBS2 FCGBP VWF VWCE MUC2 MUC5AC

4.51e-0942616IPR001007
Domain-

FBN1 FBN2 LTBP2 FBN3

7.14e-0986143.90.290.10
DomainTB

FBN1 FBN2 LTBP2 FBN3

1.28e-089614PS51364
DomainTB_dom

FBN1 FBN2 LTBP2 FBN3

1.28e-089614IPR017878
DomaincEGF

SCUBE1 FBN1 FBN2 LRP1 FBN3

1.96e-0826615IPR026823
DomaincEGF

SCUBE1 FBN1 FBN2 LRP1 FBN3

1.96e-0826615PF12662
DomainDUF3454

NOTCH1 NOTCH2 NOTCH3

3.31e-083613PF11936
DomainDUF3454_notch

NOTCH1 NOTCH2 NOTCH3

3.31e-083613IPR024600
DomainDUF3454

NOTCH1 NOTCH2 NOTCH3

3.31e-083613SM01334
DomainFBN

FBN1 FBN2 FBN3

3.31e-083613IPR011398
DomainTIL

FCGBP VWF MUC2 MUC5AC

5.00e-0812614PF01826
DomainC8

FCGBP VWF MUC2 MUC5AC

5.00e-0812614PF08742
DomainUnchr_dom_Cys-rich

FCGBP VWF MUC2 MUC5AC

7.20e-0813614IPR014853
DomainC8

FCGBP VWF MUC2 MUC5AC

7.20e-0813614SM00832
DomainTIL_dom

FCGBP VWF MUC2 MUC5AC

1.01e-0714614IPR002919
DomainVWFC_1

THBS2 VWF VWCE MUC2 MUC5AC

1.10e-0736615PS01208
DomainVWFC_2

THBS2 VWF VWCE MUC2 MUC5AC

1.45e-0738615PS50184
DomainVWC

THBS2 VWF VWCE MUC5AC

1.99e-0628614PF00093
Domain-

TENM4 NHLRC4 LRP1 TENM2

7.77e-06396142.120.10.30
DomainNHL

TENM4 NHLRC4 TENM2

9.26e-0613613PS51125
Domain6-blade_b-propeller_TolB-like

TENM4 NHLRC4 LRP1 TENM2

1.52e-0546614IPR011042
DomainCTCK_1

VWF MUC2 MUC5AC

2.61e-0518613PS01185
DomainMYT1

MYT1 ST18

3.14e-053612PF08474
DomainRhs_assc_core

TENM4 TENM2

3.14e-053612IPR022385
DomainMyelin_TF

MYT1 ST18

3.14e-053612IPR013681
DomainLaminin_G

THBS2 NRXN2 AGRN CRB2

3.83e-0558614IPR001791
DomainEGF_extracell

TENM4 LTBP2 NOTCH1 NOTCH3

4.38e-0560614IPR013111
DomainEGF_2

TENM4 LTBP2 NOTCH1 NOTCH3

4.38e-0560614PF07974
DomainCT

VWF MUC2 MUC5AC

4.88e-0522613SM00041
DomainTox-GHH_dom

TENM4 TENM2

6.27e-054612IPR028916
DomainTen_N

TENM4 TENM2

6.27e-054612IPR009471
DomainTen_N

TENM4 TENM2

6.27e-054612PF06484
DomainTENEURIN_N

TENM4 TENM2

6.27e-054612PS51361
DomainTox-GHH

TENM4 TENM2

6.27e-054612PF15636
DomainCys_knot_C

VWF MUC2 MUC5AC

7.24e-0525613IPR006207
DomainCTCK_2

VWF MUC2 MUC5AC

7.24e-0525613PS01225
DomainYD

TENM4 TENM2

1.04e-045612IPR006530
DomainZnf_FYVE_PHD

ATRX ZFYVE16 DPF2 KMT2E KAT6B

1.18e-04147615IPR011011
DomainEGF_LAM_2

LAMB4 LAMC1 AGRN

1.26e-0430613PS50027
DomainEGF_LAM_1

LAMB4 LAMC1 AGRN

1.26e-0430613PS01248
DomainZnf_PHD-finger

NFX1 DPF2 KMT2E KAT6B

1.29e-0479614IPR019787
DomainZnf_C2HC

MYT1 ST18

1.56e-046612IPR002515
Domainzf-C2HC

MYT1 ST18

1.56e-046612PF01530
DomainWxxW_domain

MUC2 MUC5AC

1.56e-046612IPR025155
DomainMucin2_WxxW

MUC2 MUC5AC

1.56e-046612PF13330
DomainLaminin_EGF

LAMB4 LAMC1 AGRN

2.01e-0435613PF00053
DomainEGF_Lam

LAMB4 LAMC1 AGRN

2.01e-0435613SM00180
DomainZF_CCHHC

MYT1 ST18

2.18e-047612PS51802
DomainLAM_G_DOMAIN

NRXN2 AGRN CRB2

2.58e-0438613PS50025
DomainLaminin_EGF

LAMB4 LAMC1 AGRN

2.58e-0438613IPR002049
DomainZF_PHD_2

ATRX DPF2 KMT2E KAT6B

2.63e-0495614PS50016
Domain-

THBS2 NRXN2 AGRN CRB2

2.63e-04956142.60.120.200
DomainZF_PHD_1

ATRX DPF2 KMT2E KAT6B

2.73e-0496614PS01359
DomainLamG

NRXN2 AGRN CRB2

3.99e-0444613SM00282
DomainFol_N

FCGBP AGRN

5.66e-0411612IPR003645
DomainFOLN

FCGBP AGRN

5.66e-0411612SM00274
DomainEGF_3

THBS2 SCUBE1

6.78e-0412612PF12947
DomainEGF_dom

THBS2 SCUBE1

6.78e-0412612IPR024731
DomainLaminin_N

LAMB4 LAMC1

1.22e-0316612IPR008211
DomainLAMININ_NTER

LAMB4 LAMC1

1.22e-0316612PS51117
DomainLaminin_N

LAMB4 LAMC1

1.22e-0316612PF00055
DomainLamNT

LAMB4 LAMC1

1.22e-0316612SM00136
DomainCarboxyPept-like_regulatory

TENM4 TENM2

1.38e-0317612IPR008969
DomainPHD

DPF2 KMT2E KAT6B

1.89e-0375613PF00628
DomainPAS_fold_3

PER1 SIM1

2.54e-0323612IPR013655
DomainPAS_3

PER1 SIM1

2.54e-0323612PF08447
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NFX1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.62e-1013435M47534
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.74e-105434M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.12e-096434M27068
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

THBS2 GNE MUC5AC AGRN NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.90e-09143438M27275
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.44e-0811434M47865
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.65e-0812434M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.65e-0812434M47533
PathwayREACTOME_DISEASES_OF_METABOLISM

THBS2 GNE MTR MUC5AC AGRN NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.01e-08250439M27554
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.26e-0813434M47423
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

THBS2 MUC5AC NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.33e-0868436M27303
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.23e-0718434M614
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3 NOTCH4

2.63e-075433MM14733
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.63e-0724434M11190
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

FBN1 FBN2 LTBP2 FBN3

9.06e-0725434M39713
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH3 NOTCH4

9.17e-077433MM14734
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.25e-0627434M39545
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.46e-0628434M6177
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

SCUBE1 FBN1 FBN2 VWF LAMC1 LTBP2 AGRN FBN3

2.91e-06300438M610
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.26e-0634434M39390
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2 LTBP2 FBN3

4.61e-0637434M27134
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMB4 THBS2 VWF LAMC1 AGRN

5.37e-0684435M7098
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2 LTBP2 FBN3

9.32e-0644434M26969
PathwayWP_NOTCH_SIGNALING_WP268

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.02e-0545434M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.12e-0546434MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.22e-0547434M7946
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

WNT4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.82e-05118435M39852
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH2 NOTCH4

2.91e-0520433M27881
PathwayPID_NOTCH_PATHWAY

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.02e-0559434M17
PathwayWP_NOTCH_SIGNALING_WP61

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.45e-0561434M39540
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH3 NOTCH4

4.49e-0523433MM14954
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

SCUBE1 FBN1 FBN2 LAMC1 FBN3

6.39e-05140435M587
PathwayWP_BREAST_CANCER_PATHWAY

WNT4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.00e-04154435M39739
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.10e-0482434MM15922
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

SCUBE1 FBN1 FBN2 VWF LTBP2 AGRN

1.22e-04258436MM14572
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2 LTBP2

1.23e-0432433MM14854
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

WNT4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.24e-04161435M39770
PathwayWP_NEOVASCULARIZATION_PROCESSES

NOTCH1 NOTCH3 NOTCH4

1.91e-0437433M39506
PathwayWP_NEURAL_CREST_DIFFERENTIATION

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.12e-0497434MM15926
PathwayREACTOME_SIGNALING_BY_NOTCH

NOTCH1 NOTCH3 NOTCH4

2.24e-0439433MM14604
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2 LTBP2

2.24e-0439433MM14601
PathwayWP_NEURAL_CREST_DIFFERENTIATION

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.47e-04101434M39448
PathwayWP_TRANSSULFURATION_PATHWAY

MPST MTR

4.03e-0410432M39324
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.62e-04119434M607
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

5.88e-0412432MM1562
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

5.88e-0412432M22042
PathwayWP_CANCER_PATHWAYS

LAMB4 LAMC1 WNT4 NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.82e-04507437M48302
PathwayWP_CYSTEINE_AND_METHIONINE_CATABOLISM

MPST MTR

9.31e-0415432M39790
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

ATRX MGA NOTCH1

1.01e-0365433M39682
PathwayPID_INTEGRIN1_PATHWAY

THBS2 FBN1 LAMC1

1.06e-0366433M18
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH4

1.06e-0316432M47424
PathwayWP_NEPHROGENESIS

WNT4 NOTCH2

1.35e-0318432M40045
PathwayWP_HEAD_AND_NECK_SQUAMOUS_CELL_CARCINOMA

SESN1 NOTCH1 NOTCH2

1.47e-0374433M39857
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC2 MUC5AC

1.84e-0321432MM15706
PathwayREACTOME_SIGNALING_BY_NOTCH4

NOTCH1 NOTCH2 NOTCH4

1.98e-0382433M594
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

FBN1 VWF AGRN

2.19e-0385433M16441
PathwayREACTOME_SULFUR_AMINO_ACID_METABOLISM

MPST MTR

2.40e-0324432MM14619
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH3

2.61e-0325432M27880
PathwayKEGG_FOCAL_ADHESION

LAMB4 THBS2 VWF LAMC1

3.09e-03199434M7253
PathwayREACTOME_SULFUR_AMINO_ACID_METABOLISM

MPST MTR

3.27e-0328432M547
PathwayREACTOME_O_LINKED_GLYCOSYLATION

THBS2 MUC2 MUC5AC

4.43e-03109433MM15164
PathwayKEGG_CYSTEINE_AND_METHIONINE_METABOLISM

MPST MTR

4.79e-0334432M10911
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

SCUBE1 FBN1 FBN2

5.02e-03114433MM14571
PathwayKEGG_PRION_DISEASES

LAMC1 NOTCH1

5.07e-0335432M13036
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462424145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462420069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462419404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462428669409
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462411401408
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-1246248898100
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462423444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462417920003
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462428061457
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462411466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462424151014
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462410194420
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462411459941
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462418184405
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.15e-12462415917835
Pubmed

Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.

VWF NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.94e-111362520558824
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.57e-11562411101851
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.57e-11562421124806
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.57e-11562423675950
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.57e-11562415882997
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

MUC2 MUC5AC NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.07e-104162622675208
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.37e-1066249111338
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.37e-10662412244553
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.37e-10662418299578
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.37e-10662415019995
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.37e-10662422615412
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.37e-10662420870902
Pubmed

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.37e-10662419503073
Pubmed

Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.37e-10662421991352
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

CHAT NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.04e-102162528656980
Pubmed

Human ligands of the Notch receptor.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.19e-10762410079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.19e-10762412846471
Pubmed

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.19e-10762411518718
Pubmed

E3 ubiquitin ligase FBXW7 balances airway cell fates.

MUC5AC NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.93e-102262534998785
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.37e-1086249858718
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.37e-10862422156581
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.37e-10862412242716
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.15e-09962411118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.15e-09962416245338
Pubmed

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.15e-09962412370315
Pubmed

Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.

MUC5AC NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.20e-092762521791528
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

MUC5AC NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.75e-092962521402740
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.91e-091062423665443
Pubmed

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.91e-091062433915108
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.99e-09116249187150
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.99e-091162416607638
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.99e-091162415499562
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.99e-091162410878608
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.99e-091162412866128
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

FBN1 FBN2 TENM4 LRP1 LAMC1 MUC5AC

3.28e-097162633541421
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.48e-091262415465494
Pubmed

Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.48e-091262410952889
Pubmed

Notch receptor expression in human brain arteriovenous malformations.

NOTCH1 NOTCH3 NOTCH4

5.39e-09362325846406
Pubmed

Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

NOTCH1 NOTCH2 NOTCH3

5.39e-0936238645602
Pubmed

Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.

NOTCH1 NOTCH2 NOTCH3

5.39e-09362327697639
Pubmed

Differential expression of Notch genes in human osteoblastic cells.

NOTCH1 NOTCH2 NOTCH4

5.39e-09362311836628
Pubmed

Notch signaling: cell fate control and signal integration in development.

NOTCH1 NOTCH2 NOTCH4

5.39e-09362310221902
Pubmed

Clinicopathological analysis of ATRX, DAXX and NOTCH receptor expression in angiosarcomas.

ATRX NOTCH1 NOTCH2

5.39e-09362328796347
Pubmed

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.

NOTCH1 NOTCH2 NOTCH3

5.39e-0936237615640
Pubmed

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.

NOTCH1 NOTCH2 NOTCH3

5.39e-0936237918097
Pubmed

Low density lipoprotein receptor-related protein-1 (LRP1) regulates thrombospondin-2 (TSP2) enhancement of Notch3 signaling.

THBS2 LRP1 NOTCH3

5.39e-09362320472562
Pubmed

Expression of Notch1 to -4 and their ligands in renal cell carcinoma: a tissue microarray study.

NOTCH1 NOTCH2 NOTCH3

5.39e-09362321471519
Pubmed

Overlapping but distinct roles for NOTCH receptors in human cardiovascular disease.

NOTCH1 NOTCH2 NOTCH3

5.39e-09362329767458
Pubmed

The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.

NOTCH1 NOTCH2 NOTCH3

5.39e-0936237698746
Pubmed

A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.47e-091362432929274
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.47e-091362411578869
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

THBS2 FBN1 VWF MIF LAMC1 LTBP2 AGRN

8.06e-0914662727068509
Pubmed

Cell-fate transition and determination analysis of mouse male germ cells throughout development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.04e-091462434824237
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.04e-091462414757642
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.23e-081562412971992
Pubmed

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.23e-081562414672936
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.64e-081662412617809
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.64e-081662417273555
Pubmed

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.64e-081662411739954
Pubmed

Notch gene expression during pancreatic organogenesis.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.64e-081662410842072
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.14e-081762418694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.14e-081762415821257
Pubmed

Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.14e-081762439315665
Pubmed

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

NOTCH1 NOTCH2 NOTCH3

2.16e-08462310551863
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN2 FBN3

2.16e-08462325034023
Pubmed

Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.

MUC2 MUC5AC NOTCH3

2.16e-08462322691042
Pubmed

Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing.

NOTCH1 NOTCH2 NOTCH3

2.16e-08462311978185
Pubmed

Novel MIR143-NOTCH fusions in benign and malignant glomus tumors.

NOTCH1 NOTCH2 NOTCH3

2.16e-08462323999936
Pubmed

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.

NOTCH1 NOTCH2 NOTCH3

2.16e-08462318156632
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.75e-081862418093989
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.75e-081862415689374
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.48e-081962416518823
Pubmed

Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.35e-082162414702043
Pubmed

Notch signaling in bulge stem cells is not required for selection of hair follicle fate.

NOTCH1 NOTCH2 NOTCH3

5.38e-08562319211676
Pubmed

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.

NOTCH1 NOTCH2 NOTCH3

5.38e-08562321562564
Pubmed

Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.

NOTCH1 NOTCH3 NOTCH4

5.38e-08562320554499
Pubmed

Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.

NOTCH2 NOTCH3 NOTCH4

5.38e-08562321726900
Pubmed

A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons.

NOTCH1 NOTCH2 NOTCH3

5.38e-08562327040987
Pubmed

Functional diversity of notch family genes in fetal lung development.

NOTCH1 NOTCH2 NOTCH3

5.38e-08562315064243
Pubmed

Notch expression in developing olfactory neuroepithelium.

NOTCH1 NOTCH2 NOTCH3

5.38e-08562315076712
Pubmed

Chimeric analysis of Notch2 function: a role for Notch2 in the development of the roof plate of the mouse brain.

NOTCH1 NOTCH2 NOTCH3

5.38e-08562312242712
Pubmed

Association of Notch pathway down-regulation with Triple Negative/Basal-like breast carcinomas and high tumor-infiltrating FOXP3+ Tregs.

NOTCH1 NOTCH2 NOTCH4

5.38e-08562327118257
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.90e-082362414701881
Pubmed

Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.90e-082362436239412
Pubmed

Rbpj regulates development of prosensory cells in the mammalian inner ear.

NOTCH1 NOTCH2 NOTCH3 NOTCH4

9.47e-082462421420948
InteractionNTN5 interactions

FBN1 FBN2 VWDE NOTCH1 NOTCH2 NOTCH3

6.26e-1124596int:NTN5
InteractionEGFL7 interactions

LDLRAD1 GNE VWCE NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.62e-0977597int:EGFL7
InteractionMAML3 interactions

NFX1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

2.71e-0920595int:MAML3
InteractionMFAP5 interactions

FBN1 FBN2 VWF SULF1 VWDE NOTCH3

8.89e-0952596int:MFAP5
InteractionZFP41 interactions

FBN1 FBN2 LRP1 AGRN NOTCH2 NOTCH3

1.57e-0857596int:ZFP41
InteractionZNF696 interactions

THBS2 TENM4 LDLRAD1 LTBP2 VWCE NOTCH2

4.61e-0868596int:ZNF696
InteractionIGFL3 interactions

FBN2 AGRN VWDE NOTCH1 NOTCH2 NOTCH3

8.35e-0875596int:IGFL3
InteractionMAML2 interactions

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.53e-0717594int:MAML2
InteractionZNF408 interactions

FBN1 FBN2 MIF LTBP2 VWCE NOTCH2 NOTCH3

2.15e-07145597int:ZNF408
InteractionZNF627 interactions

LDLRAD1 LTBP2 VWCE NOTCH2

3.10e-0720594int:ZNF627
InteractionFBN2 interactions

FBN1 FBN2 LTBP2 VWCE NOTCH2

1.31e-0665595int:FBN2
InteractionZDHHC15 interactions

FBN1 FBN2 TENM4 LRP1 LAMC1 MUC5AC

1.74e-06125596int:ZDHHC15
InteractionZNF74 interactions

LTBP2 VWCE NOTCH1 NOTCH3

2.88e-0634594int:ZNF74
InteractionZNF747 interactions

PSME3IP1 LTBP2 VWCE NOTCH2

5.60e-0640594int:ZNF747
InteractionLTBP1 interactions

FBN1 FBN2 VWCE NOTCH2 NOTCH3

7.32e-0692595int:LTBP1
InteractionIGSF5 interactions

NOTCH1 NOTCH2 NOTCH3

8.48e-0614593int:IGSF5
InteractionZNF316 interactions

LDLRAD1 LTBP2 VWCE NOTCH2

9.86e-0646594int:ZNF316
InteractionZNF324 interactions

LDLRAD1 LTBP2 VWCE NOTCH2

9.86e-0646594int:ZNF324
InteractionWNT3A interactions

LRP1 LAMC1 NOTCH1 NOTCH2

1.27e-0549594int:WNT3A
InteractionFOXD4L6 interactions

PSME3IP1 FBN2 NOTCH1 NOTCH2

1.27e-0549594int:FOXD4L6
InteractionZNF358 interactions

LTBP2 VWCE NOTCH2

2.23e-0519593int:ZNF358
InteractionFBXO2 interactions

FBN1 FBN2 SULF1 LAMC1 AGRN NOTCH1 NOTCH2 NOTCH3

2.50e-05411598int:FBXO2
InteractionNOTCH4 interactions

NOTCH2 NOTCH3 NOTCH4

3.05e-0521593int:NOTCH4
InteractionCFC1 interactions

LAMC1 AGRN VWDE NOTCH1 NOTCH2

3.37e-05126595int:CFC1
InteractionZNF77 interactions

LDLRAD1 LTBP2 VWCE

3.53e-0522593int:ZNF77
InteractionCASR interactions

NOTCH1 NOTCH2 NOTCH3

3.53e-0522593int:CASR
InteractionFBLN1 interactions

LDLRAD1 WNT4 AGRN NOTCH2 NOTCH3

3.77e-05129595int:FBLN1
InteractionLTBP4 interactions

LDLRAD1 LTBP2 VWCE NOTCH2

4.42e-0567594int:LTBP4
InteractionMAML1 interactions

NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.20e-0573594int:MAML1
InteractionNTF3 interactions

LRP1 LAMC1 VWDE

6.63e-0527593int:NTF3
InteractionHOXA1 interactions

FBN1 VWF GNE VWCE AGRN NOTCH1 NOTCH3

7.84e-05356597int:HOXA1
InteractionZNF768 interactions

LDLRAD1 NFX1 LTBP2 KMT2E NOTCH2

7.99e-05151595int:ZNF768
InteractionZNF430 interactions

LTBP2 VWCE NOTCH2

8.25e-0529593int:ZNF430
InteractionZNF707 interactions

LTBP2 NOTCH1 NOTCH2 NOTCH3

8.45e-0579594int:ZNF707
InteractionZNF664 interactions

LTBP2 VWCE NOTCH2

1.01e-0431593int:ZNF664
InteractionPSEN2 interactions

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.18e-0486594int:PSEN2
InteractionDLL4 interactions

NOTCH1 NOTCH4

1.25e-046592int:DLL4
InteractionELSPBP1 interactions

AGRN VWDE NOTCH1 NOTCH2

1.53e-0492594int:ELSPBP1
InteractionGREM2 interactions

FBN2 VWDE NOTCH2

1.73e-0437593int:GREM2
InteractionZNF594 interactions

LTBP2 NOTCH2

1.75e-047592int:ZNF594
InteractionPRG2 interactions

FBN2 LAMC1 VWDE NOTCH1 NOTCH2 NOTCH3

1.82e-04285596int:PRG2
InteractionDLL1 interactions

NOTCH1 NOTCH2 NOTCH3

1.87e-0438593int:DLL1
InteractionIGFBP4 interactions

VWDE NOTCH1 NOTCH2

2.35e-0441593int:IGFBP4
InteractionJAG1 interactions

NOTCH1 NOTCH2 NOTCH3

2.35e-0441593int:JAG1
InteractionEDN3 interactions

AGRN VWDE NOTCH1 NOTCH2

2.83e-04108594int:EDN3
InteractionZNF480 interactions

LTBP2 NOTCH2

2.99e-049592int:ZNF480
InteractionZKSCAN2 interactions

LTBP2 NOTCH2

2.99e-049592int:ZKSCAN2
InteractionNOTCH3 interactions

NOTCH1 NOTCH2 NOTCH3 NOTCH4

3.36e-04113594int:NOTCH3
InteractionST14 interactions

FBN1 FBN2 SULF1 NOTCH2 NOTCH3

3.48e-04207595int:ST14
InteractionZNF865 interactions

LDLRAD1 LTBP2 NOTCH2

3.53e-0447593int:ZNF865
InteractionZNF766 interactions

LTBP2 NOTCH2

3.73e-0410592int:ZNF766
InteractionANKRD44 interactions

NOTCH1 NOTCH2 NOTCH3

3.75e-0448593int:ANKRD44
InteractionC9orf163 interactions

PSME3IP1 NOTCH1 NOTCH2

4.49e-0451593int:C9orf163
InteractionCACNA1A interactions

VWF LRP1 AGRN NOTCH1

4.64e-04123594int:CACNA1A
InteractionIGHA1 interactions

RNGTT NFX1 AGRN ZBBX

4.93e-04125594int:IGHA1
InteractionPSEN1 interactions

PTPRN2 NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.30e-04227595int:PSEN1
InteractionZSCAN21 interactions

ZNF213 LTBP2 VWCE NOTCH2

5.39e-04128594int:ZSCAN21
InteractionMFAP2 interactions

FBN1 FBN2

5.46e-0412592int:MFAP2
InteractionZNF555 interactions

LTBP2 NOTCH2

5.46e-0412592int:ZNF555
InteractionZNF611 interactions

LTBP2 NOTCH2

5.46e-0412592int:ZNF611
InteractionZNF709 interactions

LTBP2 NOTCH2

6.44e-0413592int:ZNF709
InteractionSENP5 interactions

LDLRAD1 LTBP2 NOTCH2

6.90e-0459593int:SENP5
InteractionLFNG interactions

NOTCH1 NOTCH2

7.50e-0414592int:LFNG
InteractionRNASE4 interactions

VWDE NOTCH2

7.50e-0414592int:RNASE4
GeneFamilyZinc fingers C2H2C-type

MYT1 ST18

1.29e-0533821261
GeneFamilyPHD finger proteins

NFX1 DPF2 KMT2E KAT6B

3.72e-059038488
GeneFamilyLaminin subunits

LAMB4 LAMC1

2.80e-0412382626
GeneFamilyZinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases

ZC2HC1C KAT6B

5.07e-041638266
GeneFamilyCD molecules|Mucins

MUC2 MUC5AC

8.81e-0421382648
GeneFamilyAnkyrin repeat domain containing

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.62e-03242384403
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMB4 THBS2 FBN1 FBN2 VWF LAMC1 LTBP2 VWCE AGRN VWDE FBN3

9.30e-131966111M3008
CoexpressionNABA_CORE_MATRISOME

LAMB4 THBS2 FBN1 FBN2 VWF LAMC1 LTBP2 VWCE AGRN VWDE FBN3

3.65e-112756111M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

THBS2 FBN1 FBN2 VWF LAMC1 LTBP2 VWCE AGRN VWDE

6.00e-10191619MM17059
CoexpressionNABA_MATRISOME

LAMB4 THBS2 SCUBE1 FBN1 FBN2 VWF SULF1 LAMC1 LTBP2 WNT4 VWCE MUC2 MUC5AC AGRN VWDE FBN3

1.05e-0910266116M5889
CoexpressionNABA_CORE_MATRISOME

THBS2 FBN1 FBN2 VWF LAMC1 LTBP2 VWCE AGRN VWDE

1.24e-08270619MM17057
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.73e-0816614MM1296
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.73e-0816614M2207
CoexpressionNABA_MATRISOME

THBS2 SCUBE1 FBN1 FBN2 VWF SULF1 LAMC1 LTBP2 WNT4 VWCE MUC2 MUC5AC AGRN VWDE

5.90e-0810086114MM17056
CoexpressionHAY_BONE_MARROW_STROMAL

THBS2 SCUBE1 FBN1 TENM4 NRXN2 SULF1 LAMC1 LTBP2 WNT4 TENM2 NOTCH3

1.38e-067676111M39209
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

THBS2 FBN1 FBN2 LRP1 LAMC1 NOTCH2

7.17e-06200616M5930
CoexpressionMOREIRA_RESPONSE_TO_TSA_DN

WNT4 NOTCH1 NOTCH2

9.55e-0618613M3506
CoexpressionGAO_LARGE_INTESTINE_ADULT_CJ_IMMUNE_CELLS

FBN1 VWF SULF1 LRP1 LAMC1 LTBP2 NOTCH3 NOTCH4

2.16e-05505618M39167
CoexpressionDESCARTES_FETAL_KIDNEY_STROMAL_CELLS

THBS2 FBN1 NRXN2 SULF1 LTBP2

2.32e-05146615M40222
CoexpressionHU_FETAL_RETINA_FIBROBLAST

SCUBE1 FBN1 FBN2 SULF1 LAMC1 NOTCH2 NOTCH3

3.08e-05385617M39264
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_7

WNT4 NOTCH3 NOTCH4

3.37e-0527613M1391
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_7

WNT4 NOTCH3 NOTCH4

3.37e-0527613MM1135
CoexpressionCARRILLOREIXACH_HEPATOBLASTOMA_VS_NORMAL_HYPOMETHYLATED_AND_UP

THBS2 VWF SULF1 LAMC1 NOTCH3

3.81e-05162615M45037
CoexpressionNABA_MATRISOME_METASTATIC_COLORECTAL_LIVER_METASTASIS

THBS2 LTBP2 AGRN

4.66e-0530613M47990
CoexpressionHALLMARK_NOTCH_SIGNALING

NOTCH1 NOTCH2 NOTCH3

5.67e-0532613M5903
CoexpressionLIU_CDX2_TARGETS_UP

MUC2 NOTCH3 NOTCH4

7.44e-0535613M16637
CoexpressionHOEK_MYELOID_DENDRITIC_CELL_2011_2012_TIV_ADULT_1DY_DN

NRXN2 NOTCH3

7.94e-056612M41153
CoexpressionGSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP

PER1 LAMC1 CHAT ST18 SESN1

9.87e-05198615M4432
CoexpressionNABA_BASEMENT_MEMBRANES

LAMB4 LAMC1 AGRN

1.11e-0440613M5887
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBML1

ARFGEF3 SCUBE1 MYT1 PER1 SIM1 VWDE

1.14e-04328616M39064
CoexpressionBRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS

NOTCH1 NOTCH2

1.48e-048612M9884
CoexpressionCUI_DEVELOPING_HEART_C3_FIBROBLAST_LIKE_CELL

THBS2 FBN1 LRP1 LAMC1

1.62e-04117614M39300
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3

SCUBE1 PTPRN2 CHAT LTBP2 WNT4 SIM1

1.62e-04350616M1949
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

THBS2 FBN1 SULF1 LAMC1 LTBP2 NOTCH1 NOTCH2 NOTCH3

1.74e-04681618M39175
CoexpressionSATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER

PER1 WNT4 NOTCH3

1.81e-0447613M11213
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3

SCUBE1 PTPRN2 CHAT LTBP2 WNT4 SIM1

1.81e-04357616MM828
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_BRAIN_ENDOTHELIAL

VWF LAMC1 AGRN NOTCH1 NOTCH3 NOTCH4

2.04e-04365616M39018
CoexpressionWARTERS_IR_RESPONSE_5GY

VWCE SESN1 NOTCH1

2.17e-0450613M2601
CoexpressionWEST_ADRENOCORTICAL_TUMOR_DN

MPST TNFRSF25 ATRX LRP1 WNT4 KAT6B MUC2

2.70e-04546617M3837
CoexpressionBLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP

FBN1 FBN2 RNGTT PER1 LAMC1 NOTCH4

2.87e-04389616M6520
CoexpressionDESCARTES_FETAL_THYMUS_STROMAL_CELLS

THBS2 FBN1 FBN2 LRP1

2.96e-04137614M40313
CoexpressionCROONQUIST_STROMAL_STIMULATION_UP

THBS2 SULF1 NOTCH3

3.04e-0456613M5929
CoexpressionCHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN

FBN1 PER1 SESN1 NOTCH1

3.30e-04141614M10381
CoexpressionPARENT_MTOR_SIGNALING_UP

TNFRSF25 UBTD1 RNGTT HPS4 NFX1 LRP1 KAT6B

3.39e-04567617M16909
CoexpressionNABA_MATRISOME_HGSOC_OMENTAL_METASTASIS

THBS2 LTBP2 AGRN

3.55e-0459613M47993
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_COLORECTAL_TUMOR

THBS2 LTBP2 AGRN

3.55e-0459613M47989
CoexpressionBOQUEST_STEM_CELL_UP

THBS2 FBN1 LRP1 LTBP2 NOTCH2

3.56e-04261615M1834
CoexpressionCHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN

FBN1 PER1 SESN1 NOTCH1

3.77e-04146614MM973
CoexpressionXU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP

LTBP2 WNT4

4.09e-0413612M17359
CoexpressionANASTASSIOU_MULTICANCER_INVASIVENESS_SIGNATURE

THBS2 FBN1 SULF1

4.52e-0464613M2572
CoexpressionMULLIGHAN_MLL_SIGNATURE_2_DN

TNFRSF25 ATRX ST18 AGRN SESN1

4.82e-04279615M16867
CoexpressionBUSSLINGER_DUODENAL_PANETH_CELLS

FCGBP MUC2

5.49e-0415612M40030
CoexpressionTURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP

THBS2 FBN1 SULF1

5.63e-0469613M10165
CoexpressionACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP

PSME3IP1 SULF1 MGA ST18 VWDE

5.74e-04290615M11616
CoexpressionBUSSLINGER_DUODENAL_GOBLET_CELLS

FCGBP MUC2

6.26e-0416612M40031
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

ARFGEF3 FBN2 TENM4 SULF1 LAMC1 WNT4 SIM1 AGRN NOTCH1 NOTCH2

1.56e-073986010gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_500

FBN2 TENM4 LAMC1 WNT4 SIM1 AGRN NOTCH1

4.11e-07165607gudmap_kidney_P4_CapMesRenVes_Crym_k3_500
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200

FBN2 TENM4 LAMC1 WNT4 NOTCH2

1.10e-0665605gudmap_kidney_P3_CapMes_Crym_k4_200
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

THBS2 SCUBE1 FBN1 FBN2 TENM4 SULF1 LRP1 MTR WNT4 KAT6B SESN1 NOTCH2

1.60e-067836012gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

THBS2 SCUBE1 FBN1 FBN2 TENM4 SULF1 LRP1 MTR WNT4 KAT6B SESN1

6.17e-067406011gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

ARFGEF3 FBN1 FBN2 TENM4 SULF1 LAMC1 WNT4 SIM1 AGRN NOTCH1 NOTCH2

1.05e-057836011gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlasAravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#2

THBS2 SCUBE1 FBN1 TENM4 SULF1 MYT1 CHAT LTBP2 CSMD2 FBN3 CRB2 ZBBX

1.17e-059516012Arv_EB-LF_2500_K2
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3

SCUBE1 FBN1 FBN2 TENM4 PTPRN2 SULF1 MYT1 CHAT ADGRA1 LTBP2 ST18 CRB2

4.64e-0510946012ratio_EB_vs_SC_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

SCUBE1 MYT1 DPF2 SIM1 ST18 TENM2 NOTCH1

5.68e-05350607Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K5
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_500

SCUBE1 FBN1 FBN2 TENM4 LRP1

5.78e-05146605gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_500
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500

FBN2 TENM4 LAMC1 WNT4 NOTCH1

6.17e-05148605gudmap_kidney_P3_CapMes_Crym_k2_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500

THBS2 SCUBE1 FBN1 FBN2 SULF1 LRP1 MTR

6.43e-05357607gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_500

FBN2 TENM4 SULF1 LAMC1 WNT4 NOTCH1 NOTCH2

8.05e-05370607gudmap_kidney_P3_CapMes_Crym_500
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_200

FBN2 TENM4 LAMC1 WNT4 NOTCH2

1.06e-04166605gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500

SCUBE1 FBN1 FBN2 TENM4 SULF1 LRP1 MTR

1.08e-04388607gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

SCUBE1 NRXN2 MYT1 SIM1 ST18 AGRN TENM2

1.74e-04419607Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K1
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500

SCUBE1 FBN1 FBN2 TENM4 SULF1 LRP1 MTR

1.84e-04423607gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500
CoexpressionAtlasECTO blastocyst_vs_ECTO cord blood-Confounder_removed-fold2.0_adjp0.05

TENM4 SULF1 LTBP2 WNT4 FBN3

1.95e-04189605PCBC_ratio_ECTO blastocyst_vs_ECTO cord blood_cfr-2X-p05
CoexpressionAtlasMesoderm Day 30_vs_Mesoderm Day 15-Confounder_removed-fold2.0_adjp0.05

THBS2 FBN1 LTBP2

1.97e-0440603PCBC_ratio_MESO-30_vs_MESO-15_cfr-2X-p05
CoexpressionAtlasStromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4

THBS2 FBN1 SULF1 LRP1 LAMC1 LTBP2 NOTCH3

2.87e-04455607GSM777055_500
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500

SCUBE1 FBN1 FBN2 TENM4 LRP1

2.96e-04207605gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#2

NRXN2 MYT1 ST18

3.60e-0449603Facebase_RNAseq_e10.5_Medial Nasal Eminence_500_K2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#1_top-relative-expression-ranked_1000

TENM4 SULF1 KAT6B TENM2

3.70e-04120604gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#4

SCUBE1 NRXN2 MYT1 ST18

3.82e-04121604Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K4
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500

SCUBE1 FBN1 FBN2 LRP1

3.94e-04122604gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000

SCUBE1 TENM4 NRXN2 SULF1 MYT1 CHAT WNT4 ST18 FBN3 CRB2

4.05e-049866010PCBC_EB_fibroblast_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500

SCUBE1 NRXN2 MYT1 SIM1 ST18 TENM2 NOTCH1

4.06e-04482607Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_1000

SCUBE1 TENM4 SULF1 MYT1 CHAT WNT4 ST18 FBN3 CRB2 ZBBX

4.32e-049946010PCBC_EB_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_500

SCUBE1 SULF1 MYT1 WNT4 FBN3 CRB2 ZBBX

4.82e-04496607PCBC_EB_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500

SCUBE1 SULF1 WNT4 VWDE FBN3 CRB2 ZBBX

4.88e-04497607PCBC_ECTO_fibroblast_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500

SCUBE1 SULF1 MYT1 CHAT WNT4 FBN3 CRB2

4.88e-04497607PCBC_EB_fibroblast_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000

SCUBE1 FBN1 FBN2 TENM4 SULF1 LRP1 MTR WNT4 KAT6B

5.08e-04831609gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500

SCUBE1 FBN1 TENM4 SULF1 LRP1 NOTCH2

5.59e-04364606gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_200

LAMC1 SIM1 NOTCH1

7.20e-0462603gudmap_kidney_P4_CapMesRenVes_Crym_k3_200
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_500

SCUBE1 FBN1 FBN2 SULF1 LRP1 MTR

7.49e-04385606gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_500

TENM4 SULF1 TENM2

7.91e-0464603gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k4
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200

SCUBE1 FBN1 SULF1 LRP1

7.96e-04147604gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#5_top-relative-expression-ranked_1000

LAMC1 DPF2 SIM1 AGRN

9.01e-04152604gudmap_developingKidney_e15.5_S-shaped body_1000_k5
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

SCUBE1 FBN1 FBN2 TENM4 LRP1

9.10e-04265605gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200

SCUBE1 FBN1 SULF1 LRP1

9.24e-04153604gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_200

SCUBE1 SULF1

1.04e-0317602gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k3_200
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

SCUBE1 FBN1 FBN2 TENM4 SULF1 LRP1

1.15e-03418606gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_100

SIM1 AGRN

1.17e-0318602gudmap_developingKidney_e15.5_cortic collect duct_100_k4
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_1000

FBN1 FBN2 TENM4 SULF1 LAMC1 WNT4 NOTCH1 NOTCH2

1.17e-03749608gudmap_kidney_P3_CapMes_Crym_1000
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

FBN2 AGRN FBN3 NOTCH1 NOTCH3

1.18e-03281605PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

FBN2 AGRN FBN3 NOTCH1 NOTCH3

1.18e-03281605PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#3_top-relative-expression-ranked_500

LAMC1 SIM1 AGRN

1.21e-0374603gudmap_developingKidney_e15.5_S-shaped body_500_k3
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

THBS2 FBN1 TENM4 SULF1 LRP1 LAMC1 LTBP2 NOTCH2

2.86e-10194628d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

THBS2 FBN1 TENM4 SULF1 LRP1 LAMC1 LTBP2 NOTCH2

2.98e-10195628f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS2 FBN1 TENM4 SULF1 LRP1 LAMC1 LTBP2

7.21e-091856278f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS2 FBN1 TENM4 SULF1 LRP1 LAMC1 LTBP2

8.05e-09188627fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

THBS2 FBN1 VWF TENM4 LRP1 LAMC1 LTBP2

9.31e-0919262760b1312e84f6d6448365a952469c506c00b5fe93
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SCUBE1 FBN1 TENM4 LRP1 LTBP2 TENM2 NOTCH3

1.11e-081976275afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SCUBE1 FBN1 TENM4 LRP1 LTBP2 TENM2 NOTCH3

1.11e-081976271baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SCUBE1 FBN1 TENM4 LRP1 LTBP2 TENM2 NOTCH3

1.11e-08197627b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|Fibroblasts / Location, Cell class and cell subclass

THBS2 FBN1 SULF1 MIF LRP1 LTBP2 WNT4

1.23e-08200627f62833c63f9c6a94b6cc2ba8e2f960e67f093f48
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS2 FBN1 VWF TENM4 LAMC1 LTBP2

2.05e-07182626fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

THBS2 FBN1 FBN2 TENM4 LTBP2 TENM2

2.26e-071856267dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

THBS2 FBN1 FBN2 TENM4 LTBP2 TENM2

2.41e-071876265258674d0346e5c51a4b965efcdc1790c970845d
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 FBN1 SULF1 LRP1 LAMC1 NOTCH3

2.73e-071916261efb47743b6834b64cb0f61721ddbe875b1a66ca
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THBS2 FBN1 TENM4 SULF1 LTBP2 CSMD2

2.81e-0719262667e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THBS2 FBN1 TENM4 SULF1 LTBP2 NOTCH3

2.90e-071936265de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

THBS2 FBN1 TENM4 SULF1 LTBP2 CSMD2

2.99e-0719462603a269f75a481ea54aea8e6444605db8d6df493d
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THBS2 FBN1 TENM4 SULF1 LTBP2 NOTCH3

2.99e-071946262d66091097e106c7bee22e5281f50724700bdf8d
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THBS2 FBN1 SULF1 LAMC1 LTBP2 NOTCH3

3.08e-0719562678cfde21dde4b877fc76c8b0d5ddaabe44b912d7
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 FBN1 SULF1 LRP1 LAMC1 LTBP2

3.08e-07195626f54bc4454270ff06e85596f98199372b50d0179f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 FBN1 NRXN2 LRP1 LAMC1 LTBP2

3.08e-071956261236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

FCGBP TENM4 ATRX MYT1 CCER2 KMT2E

3.18e-0719662638da0751941adca650fe9b383d9f343153978eb5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 LTBP2 NOTCH3

3.18e-07196626fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

FCGBP TENM4 ATRX MYT1 CCER2 KMT2E

3.18e-07196626721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 LTBP2 NOTCH3

3.18e-07196626802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

THBS2 FBN1 TENM4 SULF1 LTBP2 CSMD2

3.27e-07197626f1c8936986123a3151140c374fcd62d6705c530b
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS2 FBN1 FBN2 TENM4 SULF1 LTBP2

3.27e-0719762626475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 FBN1 SULF1 LRP1 LAMC1 LTBP2

3.27e-0719762671786e9432e2d649f5d86f639abb25e7102deb67
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

THBS2 FBN1 SULF1 LAMC1 LTBP2 CSMD2

3.27e-07197626fb847f2277609c31fffcdf49517243ce0684facf
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS2 FBN1 FBN2 TENM4 SULF1 LTBP2

3.27e-07197626155e63b33302a87393ace699b2f6d73abe9c5763
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS2 FBN1 FBN2 TENM4 SULF1 LTBP2

3.37e-07198626a4005a49cf6709b543994ceb51ecd5dc46197fa9
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 FBN1 SULF1 LRP1 LAMC1 LTBP2

3.47e-071996269672230aa0bc6a7289050c955f5154ca183a5159
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 FBN1 SULF1 LRP1 LAMC1 LTBP2

3.47e-07199626e18abe678da293bd01fae55e2f9ab6fdd643d02d
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 FBN1 SULF1 LRP1 LAMC1 LTBP2

3.47e-071996261fd7bbb8727607e6507848602a19bc86882ef2d5
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THBS2 FBN1 SULF1 LRP1 LAMC1 LTBP2

3.58e-07200626b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 LTBP2

4.06e-061716255d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS2 CSMD2 TENM2 NOTCH2 NOTCH3

4.06e-061716254ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

THBS2 SCUBE1 FBN1 TENM4 LTBP2

4.30e-061736251f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell(5)_Glands_mucous|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

ARFGEF3 FCGBP LDLRAD1 PTPRN2 MUC5AC

4.94e-06178625f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

THBS2 FBN1 NRXN2 LAMC1 LTBP2

4.94e-06178625edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

THBS2 FBN1 FBN2 SULF1 LTBP2

5.36e-06181625bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 LDLRAD1 SULF1 LRP1 LAMC1

5.50e-06182625f4b74c2756989812abe4e7055ec8918f69d56025
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

THBS2 FBN1 FBN2 TENM4 LTBP2

5.96e-06185625427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 LDLRAD1 SULF1 LRP1 LAMC1

6.12e-0618662535c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

THBS2 FBN1 FBN2 TENM4 VWCE

6.12e-061866254d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 VWF NRXN2 WNT4 ZBBX

6.12e-0618662502fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 LDLRAD1 SULF1 LRP1 LAMC1

6.12e-06186625d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 PTPRN2 MYT1 ST18 VWDE

6.12e-06186625b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellControl-Fibroblasts-Pathological_FB|Control / group, cell type (main and fine annotations)

THBS2 FBN1 SULF1 LTBP2 NOTCH3

6.28e-06187625b7280b8baa0fba9c2b4bff660c240ed96f6ff9b7
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

FBN1 SULF1 LRP1 LAMC1 LTBP2

6.28e-061876254ea486991f66c29728d127171a07b81404ec0b78
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

THBS2 FBN1 TENM4 SULF1 LTBP2

6.28e-06187625a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

THBS2 FBN1 SULF1 LTBP2 NOTCH3

6.44e-0618862514bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCUBE1 FBN2 LAMC1 WNT4 CSMD2

6.44e-06188625997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 FBN1 LRP1 LAMC1 LTBP2

6.61e-06189625d531399749409d614adca13d181830c6e3287508
ToppCellwk_15-18-Mesenchymal-Fibroblast-Airway_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

THBS2 FBN1 TENM4 LTBP2 TENM2

6.61e-061896254f9608b84d135268a17455661870c46ae8554a24
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VWF SULF1 AGRN NOTCH1 NOTCH4

6.61e-061896259da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP ADGRA1 LTBP2 WNT4 AGRN

6.61e-06189625319e42f6e2322208de78bc666fb2c074707eb4da
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS2 SULF1 CSMD2 TENM2 NOTCH3

6.78e-0619062573d94fbae92029745989a8712eed8b99fd84c193
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 RNF186 WNT4 MUC5AC TENM2

6.96e-0619162505731ece7867659c662f952812805f947032fe10
ToppCellfacs-Skin|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP TENM4 MIF WNT4 TENM2

6.96e-06191625ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VWF SULF1 AGRN NOTCH1 NOTCH4

6.96e-061916253307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 MYT1 ADGRA1 ST18 VWDE

6.96e-0619162519832ddd559a353e1618fe853d79e3edfec6dcda
ToppCellmetastatic_Lymph_Node-Fibroblasts-Myofibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

LAMB4 THBS2 FBN1 SULF1 LTBP2

6.96e-06191625aa43b472bc8362f79ae63f09f1ca764718bbf22c
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 FBN1 SULF1 LRP1 LAMC1

7.14e-06192625671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 FBN1 SULF1 LRP1 LAMC1

7.14e-061926255e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 LTBP2

7.14e-06192625f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 MYT1 ADGRA1 ST18 VWDE

7.14e-061926254d3a1c267739b1479217144656986972fc86db43
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 LTBP2

7.14e-0619262541a8326cd5bc19ad5041068501bab4c72399222e
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 FBN1 SULF1 LRP1 LAMC1

7.14e-06192625840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 FBN1 SULF1 LRP1 LAMC1

7.14e-06192625136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 FBN1 NRXN2 LTBP2 CRB2

7.32e-06193625b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 LTBP2

7.32e-06193625dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellLA|World / Chamber and Cluster_Paper

FBN1 SULF1 LRP1 LAMC1 LTBP2

7.32e-06193625d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 LTBP2

7.32e-06193625e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 TENM4 GNE PTPRN2 MUC5AC

7.50e-06194625e0228f593c3493175962a4817500d4337ddc4e88
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 LTBP2

7.50e-0619462502b8102be9414d6964cd71019613edff6d88b893
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 LTBP2

7.50e-0619462529f83cdd63314fff41258937d70b881a5503bfcc
ToppCellfacs-Heart-RA-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN2 SULF1 LRP1 LAMC1 NOTCH2

7.50e-06194625bc945450b350f597c3ff910d3a14a533d90086a8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 LTBP2

7.50e-06194625d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCellfacs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN2 SULF1 LRP1 LAMC1 NOTCH2

7.69e-06195625690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCellCOVID-19-Heart-Low_count_Fib|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS2 FBN1 LRP1 LAMC1 LTBP2

7.69e-06195625e09590d1f51d5fa57fceb84c9f48f84b23d4d224
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 RNF186 PTPRN2 WNT4 TENM2

7.69e-06195625bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

FBN1 SULF1 LRP1 LAMC1 LTBP2

7.69e-06195625a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 NOTCH3

7.69e-06195625edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 LTBP2

7.69e-0619562547762d9e442fb1f6f0033e3e10f4c6e498d2c081
ToppCellfacs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN2 SULF1 LRP1 LAMC1 NOTCH2

7.69e-061956255c05e2bcea3d5d7ebe6325f7187ccf83301053d8
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THBS2 FBN1 NRXN2 SULF1 LRP1

7.89e-06196625525d6c8a277364e624e7cc586275f8a891436b57
ToppCell(5)_Fibroblast-J_(Lipofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

THBS2 NRXN2 SULF1 WNT4 CRB2

7.89e-06196625afa29399decd17fda7d63add5039ff778627ccc2
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 FBN1 LRP1 LAMC1 LTBP2

7.89e-0619662542e9828222a9663525d571633e8a454c30bfa7f8
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FBN1 SULF1 LRP1 LTBP2 CSMD2

8.08e-061976250dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCUBE1 FBN1 FBN2 LRP1 TENM2

8.08e-061976252cb1f557ce1400398975de94638126b4522567f3
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

THBS2 NOTCH1 NOTCH2 NOTCH3 CRB2

8.08e-0619762561749ccafeb938c310cff1de5ff924a1c794325a
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS2 FBN1 TENM4 NRXN2 SULF1

8.08e-061976252744cc94883c5d0424677cf5093bbab622933e9b
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS2 TENM4 SULF1 WNT4 NOTCH3

8.08e-061976256668f0da54f3bf96769275e668cd57e00b8a5ef9
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

THBS2 NOTCH1 NOTCH2 NOTCH3 CRB2

8.08e-061976259d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 FBN1 SULF1 LRP1 LTBP2

8.08e-061976254cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCellCOPD-Stromal|COPD / Disease state, Lineage and Cell class

THBS2 FBN1 SULF1 LAMC1 LTBP2

8.08e-06197625d5390d86acaa8c39f1da893e8d2271f9ed2951d7
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS2 TENM4 SULF1 WNT4 NOTCH3

8.08e-061976257c275a2ac24a9a4f83fceda93a067e754837102f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

TENM4 MYT1 LAMC1 KAT6B ST18

8.28e-061986256d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS2 FBN1 LRP1 LAMC1 LTBP2

8.28e-061986253ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS2 FBN1 TENM4 SULF1 WNT4

8.28e-061986259541d68a1a6247dbd7161a62644eea6527c2c8ff
ComputationalECM and collagens.

THBS2 FBN1 VWF LRP1 LTBP2 TENM2 NOTCH3

2.72e-05225437MODULE_47
ComputationalPlacenta genes.

TNFRSF25 FCGBP FBN2 VWF GNE PER1 LRP1 LTBP2 NOTCH3

7.20e-05463439MODULE_38
ComputationalNeighborhood of CDH11

THBS2 FBN1 LAMC1

1.29e-0425433GNF2_CDH11
ComputationalMetal / Ca ion binding.

THBS2 FBN1 FBN2 LRP1 LTBP2

1.78e-04133435MODULE_324
ComputationalTrachea genes.

TNFRSF25 FCGBP VWF GNE PTPRN2 PER1 LRP1 NOTCH3

2.04e-04415438MODULE_6
ComputationalNeighborhood of PTX3

THBS2 FBN1 LAMC1

3.88e-0436433GNF2_PTX3
ComputationalOvary genes.

THBS2 FBN1 VWF PER1 LRP1 LTBP2 NOTCH3

5.79e-04368437MODULE_1
ComputationalDRG (dorsal root ganglia) genes.

THBS2 FBN1 VWF PER1 LRP1 LTBP2 NOTCH3

7.45e-04384437MODULE_2
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

THBS2 FBN1 SULF1

1.03e-0350433GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_1
ComputationalNeighborhood of FOSL1

TNFRSF25 TENM4 ATRX MYT1 NFX1 MGA NOTCH4

1.03e-03406437MORF_FOSL1
DrugRgd Peptide

LAMB4 THBS2 FBN1 FBN2 VWF RNGTT LAMC1 FBN3

2.72e-07239628CID000104802
Drugcyadox

TNFRSF25 PER1

7.30e-062622CID005361511
Drugfuniferine N-oxide

FBN1 FBN2 LTBP2 AGRN

9.63e-0649624CID000191631
Drugerythromycin stearate

FBN2 MTR AGRN NOTCH2 NOTCH3

1.30e-05111625CID000012559
DrugTestosterone propionate [57-85-2]; Up 200; 11.6uM; PC3; HT_HG-U133A

LAMB4 TNFRSF25 PER1 ZC2HC1C MUC2 NOTCH2

1.42e-051936264676_UP
DrugAcyclovir [59277-89-3]; Up 200; 17.8uM; PC3; HT_HG-U133A

LAMB4 TNFRSF25 SULF1 NFX1 PER1 ZC2HC1C

1.55e-051966264683_UP
DrugChloramphenicol [56-75-7]; Up 200; 12.4uM; PC3; HT_HG-U133A

TNFRSF25 PTPRN2 SULF1 PER1 ZC2HC1C NOTCH2

1.64e-051986265047_UP
DrugPractolol [6673-35-4]; Up 200; 15uM; PC3; HT_HG-U133A

LAMB4 TNFRSF25 SULF1 MYT1 ZC2HC1C MUC2

1.64e-051986264603_UP
DrugB-08

FBN2 GNE

2.18e-053622CID016086421
Druggamma-secretase inhibitor I

NOTCH2 NOTCH3

4.36e-054622CID011754711
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN2 FBN3

7.21e-093583DOID:65 (implicated_via_orthology)
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

2.51e-077583DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

2.51e-077583DOID:3620 (implicated_via_orthology)
DiseaseMarfan Syndrome

FBN1 LAMC1 LTBP2

1.18e-0611583C0024796
Diseasecystitis (is_marker_for)

MUC2 MUC5AC

3.80e-062582DOID:1679 (is_marker_for)
DiseaseMalignant neoplasm of skin

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.64e-0659584C0007114
DiseaseSkin Neoplasms

NOTCH1 NOTCH2 NOTCH3 NOTCH4

5.64e-0659584C0037286
Diseasesputum mucin-5B amount

MUC2 MUC5AC

1.14e-053582OBA_2050332
DiseaseWeill-Marchesani syndrome

FBN1 LTBP2

1.14e-053582C0265313
DiseaseWeill-Marchesani Syndrome, Autosomal Dominant

FBN1 LTBP2

1.14e-053582C1869115
DiseaseWeill-Marchesani Syndrome, Autosomal Recessive

FBN1 LTBP2

1.14e-053582C1869114
DiseaseCarcinoma, Pancreatic Ductal

NOTCH1 NOTCH3 NOTCH4

1.42e-0524583C0887833
Diseasebrain cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

1.81e-0526583DOID:1319 (implicated_via_orthology)
Diseasescoliosis (is_implicated_in)

FBN1 FBN2

2.27e-054582DOID:0060249 (is_implicated_in)
DiseaseWeill-Marchesani syndrome

FBN1 LTBP2

2.27e-054582cv:C0265313
DiseaseWeill-Marchesani syndrome (is_implicated_in)

FBN1 LTBP2

2.27e-054582DOID:0050475 (is_implicated_in)
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

2.82e-0530583DOID:9256 (implicated_via_orthology)
Diseaseintestinal cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

3.43e-0532583DOID:10155 (implicated_via_orthology)
Diseasemucinous adenocarcinoma (is_marker_for)

MUC2 MUC5AC

3.78e-055582DOID:3030 (is_marker_for)
DiseaseMalignant neoplasm of breast

VWF MIF PER1 MTR SIM1 KAT6B NOTCH1 NOTCH2 NOTCH3 NOTCH4

4.17e-0510745810C0006142
Diseaseamino acid measurement

UBTD1 VWF TENM4 ZFYVE16 PTPRN2 MYT1 MUC2 NOTCH1

5.19e-05678588EFO_0005134
Diseaseobesity (implicated_via_orthology)

SIM1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

6.56e-05215585DOID:9970 (implicated_via_orthology)
DiseaseLymphoma

MTR NOTCH1 NOTCH2

6.76e-0540583C0024299
DiseaseGlioblastoma Multiforme

ATRX NOTCH1 NOTCH2 NOTCH3

6.88e-05111584C1621958
Diseasepulse pressure measurement

THBS2 FBN1 FBN2 TENM4 MYT1 MIF LRP1 ZC2HC1C LTBP2 ST18 NOTCH3

7.29e-0513925811EFO_0005763
DiseaseMammary Carcinoma, Human

MIF MTR SIM1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.44e-05525587C4704874
DiseaseMammary Neoplasms, Human

MIF MTR SIM1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.44e-05525587C1257931
DiseaseMammary Neoplasms

MIF MTR SIM1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

7.62e-05527587C1458155
DiseaseBreast Carcinoma

MIF MTR SIM1 NOTCH1 NOTCH2 NOTCH3 NOTCH4

8.67e-05538587C0678222
Diseasemesangial proliferative glomerulonephritis (biomarker_via_orthology)

FBN1 VWF

1.06e-048582DOID:4783 (biomarker_via_orthology)
DiseaseSquamous cell carcinoma

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.06e-04124584C0007137
Diseasepulmonary fibrosis (biomarker_via_orthology)

VWF MUC5AC NOTCH1

1.32e-0450583DOID:3770 (biomarker_via_orthology)
Diseasehemangiopericytoma (is_marker_for)

NOTCH1 NOTCH4

1.35e-049582DOID:264 (is_marker_for)
DiseaseMarfan Syndrome, Type I

FBN1 LAMC1

1.35e-049582C4721845
Diseasebringing up phlegm, sputum or mucus on most days, self-reported

MUC2 MUC5AC

1.35e-049582EFO_0009824
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN1 FBN2 NOTCH1

1.57e-0453583C4707243
Diseaseaortic aneurysm

FBN1 LRP1

1.69e-0410582EFO_0001666
Diseasecolorectal cancer

SCUBE1 FBN1 PTPRN2 LRP1 LAMC1 WNT4 NOTCH4

1.77e-04604587MONDO_0005575
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

MPST FBN1 MIF MTR

2.04e-04147584DOID:9352 (biomarker_via_orthology)
Diseasecholangiocarcinoma (is_marker_for)

MUC2 MUC5AC NOTCH1

2.76e-0464583DOID:4947 (is_marker_for)
Diseasecolitis (implicated_via_orthology)

MIF MUC2

2.92e-0413582DOID:0060180 (implicated_via_orthology)
DiseaseMigraine Disorders

LRP1 NOTCH3

2.92e-0413582C0149931
DiseaseSchizophrenia

TENM4 NRXN2 HPS4 LRP1 MTR CHAT CSMD2 NOTCH4

3.18e-04883588C0036341
DiseaseNeoplasm of uncertain or unknown behavior of bladder

NOTCH1 NOTCH2

3.92e-0415582C0496930
DiseaseBenign neoplasm of bladder

NOTCH1 NOTCH2

3.92e-0415582C0154017
DiseaseCarcinoma in situ of bladder

NOTCH1 NOTCH2

3.92e-0415582C0154091
Diseaseuterine prolapse

FBN2 WNT4

4.48e-0416582EFO_1001864
DiseaseGlioblastoma

NOTCH1 NOTCH2 NOTCH3

5.13e-0479583C0017636
DiseaseCarcinoma of bladder

NOTCH1 NOTCH2

5.69e-0418582C0699885
Diseasealcohol use disorder (implicated_via_orthology)

DPF2 NOTCH1 NOTCH2 NOTCH3

5.94e-04195584DOID:1574 (implicated_via_orthology)
DiseaseGiant Cell Glioblastoma

NOTCH1 NOTCH2 NOTCH3

6.13e-0484583C0334588
DiseaseFEV/FEC ratio

FBN1 FCGBP SULF1 LRP1 LTBP2 WNT4 MGA TSEN2 CRB2

6.16e-041228589EFO_0004713
Diseaseanorectal malformation

THBS2 CSMD2

6.36e-0419582MONDO_0019938
Diseasevital capacity

THBS2 SULF1 MYT1 PER1 LTBP2 WNT4 KMT2E TENM2 FBN3

6.46e-041236589EFO_0004312
Diseasediffuse plaque measurement

ARFGEF3 FBN2 TENM4 PTPRN2 KAT6B FBN3 NOTCH4

6.92e-04758587EFO_0010699
DiseaseSquamous cell carcinoma of esophagus

NOTCH1 NOTCH2 NOTCH3

8.77e-0495583C0279626
DiseaseS-warfarin to R-warfarin ratio measurement

ARFGEF3 LDLRAD1 WNT4

8.77e-0495583EFO_0803331
DiseaseSeizures

MTR CHAT KMT2E NOTCH3

9.00e-04218584C0036572
DiseaseAdenoid Cystic Carcinoma

ATRX MGA NOTCH1

1.02e-03100583C0010606
Diseasesystemic scleroderma (is_implicated_in)

FBN1 NOTCH4

1.02e-0324582DOID:418 (is_implicated_in)
DiseaseBell's palsy

TENM4 MYT1 MGA

1.08e-03102583EFO_0007167
DiseaseCerebral Astrocytoma

NOTCH1 NOTCH2

1.11e-0325582C0750935
DiseaseIntracranial Astrocytoma

NOTCH1 NOTCH2

1.11e-0325582C0750936
DiseasePilocytic Astrocytoma

NOTCH1 NOTCH2

1.11e-0325582C0334583
DiseaseAstrocytoma

NOTCH1 NOTCH2

1.11e-0325582C0004114
DiseaseJuvenile Pilocytic Astrocytoma

NOTCH1 NOTCH2

1.11e-0325582C0280783
DiseaseDiffuse Astrocytoma

NOTCH1 NOTCH2

1.11e-0325582C0280785
DiseaseGrade I Astrocytoma

NOTCH1 NOTCH2

1.11e-0325582C1704230
DiseaseSubependymal Giant Cell Astrocytoma

NOTCH1 NOTCH2

1.11e-0325582C0205768
DiseaseMixed oligoastrocytoma

NOTCH1 NOTCH2

1.11e-0325582C0547065
DiseaseChildhood Cerebral Astrocytoma

NOTCH1 NOTCH2

1.11e-0325582C0338070
Diseasediabetes mellitus (implicated_via_orthology)

PTPRN2 LRP1

1.20e-0326582DOID:9351 (implicated_via_orthology)
DiseaseGemistocytic astrocytoma

NOTCH1 NOTCH2

1.20e-0326582C0334581
DiseaseProtoplasmic astrocytoma

NOTCH1 NOTCH2

1.20e-0326582C0334580
DiseaseFibrillary Astrocytoma

NOTCH1 NOTCH2

1.20e-0326582C0334582
DiseaseAnaplastic astrocytoma

NOTCH1 NOTCH2

1.29e-0327582C0334579
Diseaseurate measurement, bone density

PTPRN2 SULF1 SIM1 KAT6B TENM2 NOTCH4

1.33e-03619586EFO_0003923, EFO_0004531
Diseasecortical thickness

SCUBE1 FBN1 FBN2 LRP1 LAMC1 ST18 TENM2 CRB2

1.44e-031113588EFO_0004840
DiseaseHyperglycemia, Postprandial

FBN1 SIM1

1.59e-0330582C1855520
DiseaseHyperglycemia

FBN1 SIM1

1.59e-0330582C0020456
Diseasebody surface area

FBN1 FBN2 PER1 LTBP2 WNT4 SIM1

1.62e-03643586EFO_0022196
Diseaseadult onset asthma

LRP1 MUC2 MUC5AC

1.64e-03118583EFO_1002011
Diseasespontaneous coronary artery dissection

FBN1 LRP1

1.70e-0331582EFO_0010820
DiseaseAutistic Disorder

NRXN2 MIF PER1 KMT2E

1.74e-03261584C0004352
DiseaseAlcoholic Intoxication

MTR CHAT

1.81e-0332582C0001969
Diseasecancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3 NOTCH4

1.92e-03268584DOID:162 (implicated_via_orthology)
Diseasejoint hypermobility measurement

THBS2 NOTCH4

1.93e-0333582EFO_0007905

Protein segments in the cluster

PeptideGeneStartEntry
GSEVRCLAGHCGTPE

CSMD2

2706

Q7Z408
TGSLPHCSGTSVGVC

CSMD2

2821

Q7Z408
HCSGTSVGVCGDPGI

CSMD2

2826

Q7Z408
LHVASAGPCETCGDA

AGRN

591

O00468
DGPAGTHTLACCTQG

ADGRA1

461

Q86SQ6
IDECSTHSGICGPGT

FBN3

1606

Q75N90
DTDECSVGHPCGQGT

FBN3

2126

Q75N90
GRSCPIIVHCSDGAG

PTPRN2

936

Q92932
PEELLSCADCGSSGH

KAT6B

231

Q8WYB5
SHPCLNEGTCVDGLG

NOTCH2

1031

Q04721
TGDVTHECACLPGFT

NOTCH1

236

P46531
CKGHGECPTTENTET

RNGTT

91

O60942
GCATVKPSEHSCITG

MGA

2041

Q8IWI9
ASAPCLHGGSCLDGV

CRB2

151

Q5IJ48
GCSHNCSVAPGEGIV

LRP1

1191

Q07954
TDGRVAPSCLTCVGH

LRP1

4366

Q07954
GVCESHAAPGLECSS

HPS4

496

Q9NQG7
ACVDCGSSTQDPGHP

PER1

1201

O15534
GCISHCSSDAGVSPG

OR3A4P

301

P47883
PCPGTCALEGGSHIT

MUC2

386

Q02817
VLAPGEVGCDCSHTG

NRXN2

221

Q9P2S2
GPHGICTNLAGSFSC

NOTCH3

821

Q9UM47
HEGDCGPCSRTSVIS

NFX1

646

Q12986
GHGCCTRELGTEEPT

KDM4E

456

B2RXH2
SGGESPCVSCSPSHV

KMT2E

1281

Q8IZD2
PASGVCDGVRTCTHG

LDLRAD1

91

Q5T700
GGSSEPCALCSLHSI

MIF

51

P14174
PNGESVHDSGAICTC

MUC5AC

771

P98088
PGDTGAGCQKSCHTL

MUC5AC

816

P98088
HTFGCPAGICSNSEG

NHLRC4

46

P0CG21
GEDGLHGIVSCTACG

ATRX

161

P46100
VVSLDGPDCSCGSHG

GNE

571

Q9Y223
CGTEPHGCASTEEKG

CCER2

66

I3L3R5
GEVSCEPSSCGPHET

FCGBP

2421

Q9Y6R7
GGEVSCEPSSCGPHE

FCGBP

3621

Q9Y6R7
PGICEGGECTNTVSS

FBN1

296

P35555
PGVSDHGRGSGCSCT

ARFGEF3

296

Q5TH69
DPCVGGHCVNTEGSF

LTBP2

1226

Q14767
ECDPDGTISGGICVS

LAMB4

396

A4D0S4
GTISGGICVSHSDPA

LAMB4

401

A4D0S4
GVTGVTKSCHLCDAG

LAMC1

81

P11047
PGICETGECSNTVGS

FBN2

326

P35556
GSFHCECPEGLTLDG

FBN2

976

P35556
GGCQHSCEDTDTGPT

SCUBE1

211

Q8IWY4
PAGGHSGSTECDLEC

RNF186

26

Q9NXI6
GCLQEGSGCHPTTES

TSEN2

191

Q8NCE0
ATCGSGVTACHVALG

MPST

246

P25325
TFGCGISPEIHCDGG

SESN1

216

Q9Y6P5
SGPSIHCPSAAVCIG

PSME3IP1

196

Q9GZU8
GGCCGSTPDHIREIA

MTR

321

Q99707
GEVCHGSALANTSPC

SIM1

616

P81133
SGHGTYLPDTGLCSC

TENM2

711

Q9NT68
ELGGCISAPCAHGGT

NOTCH4

691

Q99466
LITCPTPGCDGSGHV

ST18

721

O60284
GRDGTCGVVCEHSPF

CHAT

431

P28329
HPCGSDETETGGDCV

VWDE

166

Q8N2E2
DGNVSSCGDHPSEGC

VWF

2221

P04275
HGDTEAPVNCSSCPG

VWCE

771

Q96DN2
ELVSCSDCGRSGHPS

DPF2

291

Q92785
TPRATCLDQCSGHGT

TENM4

691

Q6N022
CLDQCSGHGTFLPDT

TENM4

696

Q6N022
SGHGTFLPDTGLCSC

TENM4

701

Q6N022
DGASITLPHGTLCEC

UBTD1

91

Q9HAC8
EHGDGCVSCPTSTLG

TNFRSF25

171

Q93038
GSIEEPQLGECSHCG

ZC2HC1C

381

Q53FD0
PGETTDTCFVSGVHG

ZNF213

186

O14771
CGCDRTVHGVSPQGF

WNT4

136

P56705
SCPVGFLGNGTHCED

THBS2

576

P35442
GEECSLPGLTCFTHD

SULF1

736

Q8IWU6
TSHVRGPCGVEELSC

ZBBX

746

A8MT70
GTHVPESSDCCEGFI

ZFYVE16

486

Q7Z3T8
ADLSCPTPGCTGSGH

MYT1

26

Q01538
ELLTCPTPGCDGSGH

MYT1

796

Q01538