Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 OR4C12 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16 OR4A4P

7.03e-114318916GO:0004984
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 CCR3 OR4C12 OR2T12 OR4X1 LGR5 OR10T2 OR56B4 OR14A16 OR4A4P

5.60e-088848918GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 CCR3 OR4C12 LTBP1 OR2T12 CR1 OR4X1 LGR5 OR10T2 OR56B4 OR14A16 IL23R OR4A4P

3.67e-0713538921GO:0004888
GeneOntologyMolecularFunctionextracellular matrix structural constituent

MATN2 LAMB1 MATN4 LTBP1 EDIL3 MUC2 SSPOP FBN3

1.96e-06188898GO:0005201
GeneOntologyMolecularFunctioncalcium ion binding

NELL2 SCUBE1 CAMKK2 MATN2 DLL3 LRP2 SCUBE3 MATN4 LTBP1 EDIL3 FBN3

4.89e-047498911GO:0005509
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

IKZF3 PCGF2 ZC3H4 EP300

5.18e-0483894GO:1990841
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 OR4C12 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16 OR4A4P

4.54e-114328916GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 OR4C12 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16 OR4A4P

1.34e-104658916GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 OR4C12 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16 OR4A4P

2.49e-104858916GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 OR4C12 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16 OR4A4P

7.66e-105248916GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 OR4C12 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16 OR4A4P

1.42e-095478916GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 OR4C12 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16 OR4A4P

3.45e-095828916GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 OR4C12 RP1 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16 OR4A4P

1.06e-087228917GO:0051606
GeneOntologyBiologicalProcesspositive regulation of integrin-mediated signaling pathway

PCSK5 LIMS1 LAMB1 LIMS2

3.14e-0714894GO:2001046
GeneOntologyBiologicalProcesssensory perception

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 LRP2 OR6Y1 OR5A2 OR4C13 OR4C12 RP1 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16 OR4A4P

6.04e-0710728918GO:0007600
GeneOntologyBiologicalProcessregulation of integrin-mediated signaling pathway

PCSK5 LIMS1 LAMB1 LIMS2

2.69e-0623894GO:2001044
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

PRKD2 OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 CCR3 OR4C12 OR2T12 OR4X1 LGR5 OR10T2 OR56B4 OR14A16 OR4A4P

6.25e-0613958919GO:0007186
GeneOntologyBiologicalProcessnegative regulation of cholangiocyte proliferation

LIMS1 LIMS2

5.51e-053892GO:1904055
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

CFLAR PRKD2 ZNF423 LRP2 SCUBE3 LTBP1 GDF3 EP300 DKK3

7.20e-05412899GO:0090287
GeneOntologyBiologicalProcessnegative regulation of cortisol biosynthetic process

BMP5 DKK3

1.10e-044892GO:2000065
GeneOntologyBiologicalProcessnegative regulation of aldosterone metabolic process

BMP5 DKK3

1.10e-044892GO:0032345
GeneOntologyBiologicalProcessnegative regulation of aldosterone biosynthetic process

BMP5 DKK3

1.10e-044892GO:0032348
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

BMP5 ZNF423 LRP2 SCUBE3 LTBP1 GDF3 EP300 DKK3

1.28e-04347898GO:0090092
GeneOntologyBiologicalProcessnegative regulation of glucocorticoid metabolic process

BMP5 DKK3

1.83e-045892GO:0031944
GeneOntologyBiologicalProcessnegative regulation of glucocorticoid biosynthetic process

BMP5 DKK3

1.83e-045892GO:0031947
GeneOntologyBiologicalProcessnegative regulation of steroid hormone biosynthetic process

BMP5 DKK3

2.73e-046892GO:0090032
GeneOntologyBiologicalProcesssomitogenesis

DLL3 POFUT1 GDF3 EP300

3.28e-0476894GO:0001756
GeneOntologyBiologicalProcessregulation of cortisol biosynthetic process

BMP5 DKK3

3.81e-047892GO:2000064
GeneOntologyBiologicalProcesspattern specification process

PCSK5 BMP5 PCGF2 DLL3 LRP2 POFUT1 GDF3 DNAH5 EP300

4.43e-04526899GO:0007389
GeneOntologyBiologicalProcessregulation of cholangiocyte proliferation

LIMS1 LIMS2

5.07e-048892GO:1904054
GeneOntologyBiologicalProcessregulation of aldosterone biosynthetic process

BMP5 DKK3

5.07e-048892GO:0032347
GeneOntologyBiologicalProcessnegative regulation of hepatocyte apoptotic process

CFLAR LIMS1

5.07e-048892GO:1903944
GeneOntologyBiologicalProcesspositive regulation of T-helper 17 cell lineage commitment

EP300 IL23R

5.07e-048892GO:2000330
GeneOntologyBiologicalProcessregulation of hepatocyte proliferation

CFLAR LIMS1 LIMS2

5.87e-0438893GO:2000345
GeneOntologyBiologicalProcessmesoderm development

IKZF3 DLL3 IKZF1 EXT2 GDF3

5.95e-04157895GO:0007498
GeneOntologyBiologicalProcessregulation of glucocorticoid biosynthetic process

BMP5 DKK3

6.50e-049892GO:0031946
GeneOntologyBiologicalProcessregulation of aldosterone metabolic process

BMP5 DKK3

6.50e-049892GO:0032344
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

BMP5 ZNF423 LRP2 SCUBE3 LTBP1 GDF3 EP300 DKK3

6.77e-04445898GO:0141091
GeneOntologyBiologicalProcessanterior/posterior pattern specification

PCSK5 PCGF2 DLL3 POFUT1 GDF3 EP300

7.04e-04247896GO:0009952
GeneOntologyBiologicalProcesssomite development

DLL3 POFUT1 GDF3 EP300

7.35e-0494894GO:0061053
GeneOntologyBiologicalProcesscortisol biosynthetic process

BMP5 DKK3

8.10e-0410892GO:0034651
GeneOntologyBiologicalProcesstertiary alcohol biosynthetic process

BMP5 DKK3

8.10e-0410892GO:1902645
GeneOntologyBiologicalProcesscholangiocyte proliferation

LIMS1 LIMS2

8.10e-0410892GO:1990705
GeneOntologyBiologicalProcesspositive regulation of cell adhesion

PCSK5 PRKD2 LIMS1 LAMB1 CR1 EDIL3 EP300 IL23R LIMS2

8.80e-04579899GO:0045785
GeneOntologyBiologicalProcessregulation of glucocorticoid metabolic process

BMP5 DKK3

9.87e-0411892GO:0031943
GeneOntologyBiologicalProcessnegative regulation of hormone biosynthetic process

BMP5 DKK3

9.87e-0411892GO:0032353
GeneOntologyBiologicalProcessaldosterone biosynthetic process

BMP5 DKK3

9.87e-0411892GO:0032342
GeneOntologyBiologicalProcessregulation of hepatocyte apoptotic process

CFLAR LIMS1

9.87e-0411892GO:1903943
GeneOntologyBiologicalProcessregulation of T-helper 17 cell lineage commitment

EP300 IL23R

9.87e-0411892GO:2000328
GeneOntologyBiologicalProcessepithelial cell proliferation involved in liver morphogenesis

CFLAR LIMS1 LIMS2

1.03e-0346893GO:0072575
GeneOntologyBiologicalProcesshepatocyte proliferation

CFLAR LIMS1 LIMS2

1.03e-0346893GO:0072574
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

CFLAR PRKD2 BMP5 ZNF423 LRP2 SCUBE3 LTBP1 EXT2 GDF3 EP300 DKK3

1.06e-038508911GO:0071363
GeneOntologyBiologicalProcessregionalization

PCSK5 PCGF2 DLL3 LRP2 POFUT1 GDF3 DNAH5 EP300

1.07e-03478898GO:0003002
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

BMP5 ZNF423 LRP2 SCUBE3 LTBP1 GDF3 EP300 DKK3

1.13e-03482898GO:0007178
GeneOntologyBiologicalProcesscortisol metabolic process

BMP5 DKK3

1.18e-0312892GO:0034650
GeneOntologyCellularComponentmatrilin complex

MATN2 MATN4

1.09e-044902GO:0120216
MousePhenovascular ring

PCSK5 LRP2 LTBP1 DNAH5

1.55e-0535614MP:0010466
MousePhenoabsent xiphoid process

PCSK5 BMP5

1.87e-052612MP:0011872
MousePhenoabnormal thoracic vertebrae morphology

PCSK5 BMP5 PCGF2 DLL3 SCUBE3

1.01e-04107615MP:0003047
MousePhenoright aortic arch

PCSK5 LRP2 LTBP1 DNAH5

1.33e-0460614MP:0004158
MousePhenoabnormal craniofacial morphology

PCSK5 BMP5 LIMK2 SCUBE1 PCGF2 ZNF423 ARPC1A DLL3 LRP2 SCUBE3 ZNF521 LTBP1 LGR5 EDIL3 DNAH5 EP300

1.92e-0413726116MP:0000428
MousePhenocraniofacial phenotype

PCSK5 BMP5 LIMK2 SCUBE1 PCGF2 ZNF423 ARPC1A DLL3 LRP2 SCUBE3 ZNF521 LTBP1 LGR5 EDIL3 DNAH5 EP300

1.92e-0413726116MP:0005382
MousePhenoabnormal neural tube morphology

PCSK5 SCUBE1 ZC3H4 ARPC1A DLL3 LRP2 LTBP1 POFUT1 BRD1 EP300

2.17e-045916110MP:0002151
MousePhenoabnormal embryonic tissue morphology

PCSK5 BMP5 SCUBE1 LIMS1 ZC3H4 ARPC1A DLL3 LRP2 LTBP1 EXT2 POFUT1 BRD1 GDF3 EP300

2.52e-0411166114MP:0002085
MousePhenoabnormal elastic cartilage morphology

BMP5 EDIL3

2.78e-046612MP:0006430
MousePhenounilateral cryptorchism

BMP5 LRP2

2.78e-046612MP:0031286
MousePhenoabnormal outer ear cartilage morphology

BMP5 EDIL3

2.78e-046612MP:0030422
DomaincEGF

SCUBE1 MATN2 LRP2 SCUBE3 MATN4 LTBP1 FBN3

2.10e-1126867IPR026823
DomaincEGF

SCUBE1 MATN2 LRP2 SCUBE3 MATN4 LTBP1 FBN3

2.10e-1126867PF12662
DomainGrowth_fac_rcpt_

PCSK5 NELL2 SCUBE1 MATN2 DLL3 LRP2 SCUBE3 LAMB1 MATN4 LTBP1 FBN3

1.38e-101568611IPR009030
DomainEGF_CA

NELL2 SCUBE1 MATN2 DLL3 LRP2 SCUBE3 MATN4 LTBP1 EDIL3 FBN3

2.27e-101228610SM00179
DomainEGF-like_Ca-bd_dom

NELL2 SCUBE1 MATN2 DLL3 LRP2 SCUBE3 MATN4 LTBP1 EDIL3 FBN3

2.67e-101248610IPR001881
DomainOlfact_rcpt

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 OR4C12 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16

3.01e-103938615IPR000725
DomainEGF

PCSK5 NELL2 SCUBE1 MATN2 DLL3 LRP2 SCUBE3 LAMB1 MATN4 LTBP1 EDIL3 FBN3

8.00e-102358612SM00181
DomainASX_HYDROXYL

NELL2 SCUBE1 MATN2 LRP2 SCUBE3 MATN4 LTBP1 EDIL3 FBN3

8.20e-10100869PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

NELL2 SCUBE1 MATN2 LRP2 SCUBE3 MATN4 LTBP1 EDIL3 FBN3

1.38e-09106869IPR000152
DomainEGF-like_dom

PCSK5 NELL2 SCUBE1 MATN2 DLL3 LRP2 SCUBE3 LAMB1 MATN4 LTBP1 EDIL3 FBN3

1.55e-092498612IPR000742
DomainEGF_2

NELL2 SCUBE1 MATN2 DLL3 LRP2 SCUBE3 LAMB1 MATN4 LTBP1 EDIL3 SSPOP FBN3

3.13e-092658612PS01186
DomainEGF_CA

NELL2 SCUBE1 MATN2 LRP2 SCUBE3 MATN4 LTBP1 FBN3

5.74e-0986868PF07645
DomainGPCR_Rhodpsn_7TM

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 CCR3 OR4C12 OR2T12 OR4X1 LGR5 OR10T2 OR56B4 OR14A16

8.72e-096708617IPR017452
Domain7tm_1

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 CCR3 OR4C12 OR2T12 OR4X1 LGR5 OR10T2 OR56B4 OR14A16

1.02e-086778617PF00001
DomainEGF_3

NELL2 SCUBE1 MATN2 DLL3 LRP2 SCUBE3 MATN4 LTBP1 EDIL3 SSPOP FBN3

1.06e-082358611PS50026
DomainG_PROTEIN_RECEP_F1_1

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 CCR3 OR4C12 OR2T12 OR4X1 LGR5 OR10T2 OR56B4 OR14A16

1.21e-086858617PS00237
DomainG_PROTEIN_RECEP_F1_2

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 CCR3 OR4C12 OR2T12 OR4X1 LGR5 OR10T2 OR56B4 OR14A16

1.37e-086918617PS50262
DomainGPCR_Rhodpsn

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 CCR3 OR4C12 OR2T12 OR4X1 LGR5 OR10T2 OR56B4 OR14A16

1.40e-086928617IPR000276
DomainEGF_1

NELL2 SCUBE1 DLL3 LRP2 SCUBE3 LAMB1 MATN4 LTBP1 EDIL3 SSPOP FBN3

2.46e-082558611PS00022
DomainEGF-like_CS

NELL2 SCUBE1 MATN2 DLL3 LRP2 SCUBE3 LAMB1 MATN4 LTBP1 EDIL3 FBN3

3.12e-082618611IPR013032
DomainEGF

MATN2 DLL3 LRP2 SCUBE3 MATN4 LTBP1 EDIL3 FBN3

1.17e-07126868PF00008
DomainEGF_Ca-bd_CS

NELL2 SCUBE1 LRP2 SCUBE3 LTBP1 EDIL3 FBN3

3.15e-0797867IPR018097
DomainEGF_CA

NELL2 SCUBE1 LRP2 SCUBE3 LTBP1 EDIL3 FBN3

3.62e-0799867PS01187
DomainTIL_dom

LRP2 MUC2 SSPOP

3.31e-0514863IPR002919
DomainPINCH

LIMS1 LIMS2

6.27e-053862IPR017351
DomainVWC_out

NELL2 MUC2 SSPOP

8.66e-0519863SM00215
Domain-

MATN2 MATN4

1.25e-0448621.20.5.30
DomainMatrilin_ccoil

MATN2 MATN4

1.25e-044862PF10393
DomainMatrilin_coiled-coil_trimer

MATN2 MATN4

1.25e-044862IPR019466
DomainMatrilin_ccoil

MATN2 MATN4

1.25e-044862SM01279
DomainEGF_extracell

NELL2 DLL3 LRP2 EDIL3

1.68e-0460864IPR013111
DomainEGF_2

NELL2 DLL3 LRP2 EDIL3

1.68e-0460864PF07974
DomainEphrin_rec_like

PCSK5 SCUBE1 SCUBE3

2.01e-0425863SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

PCSK5 SCUBE1 SCUBE3

2.01e-0425863IPR011641
DomainTGFb_propeptide

BMP5 INHBC GDF3

2.84e-0428863PF00688
DomainhEGF

DLL3 EDIL3 FBN3

2.84e-0428863PF12661
DomainTGF-b_N

BMP5 INHBC GDF3

2.84e-0428863IPR001111
DomainTGF-beta-rel

BMP5 INHBC GDF3

4.25e-0432863IPR015615
DomainTGFb_CS

BMP5 INHBC GDF3

4.25e-0432863IPR017948
DomainTB

LTBP1 FBN3

4.34e-047862PF00683
Domain-

LTBP1 FBN3

5.76e-0488623.90.290.10
DomainVWFC_1

NELL2 MUC2 SSPOP

6.03e-0436863PS01208
DomainTGFB

BMP5 INHBC GDF3

6.54e-0437863SM00204
DomainTGF-b_C

BMP5 INHBC GDF3

6.54e-0437863IPR001839
DomainTGF_BETA_2

BMP5 INHBC GDF3

6.54e-0437863PS51362
DomainTGF_beta

BMP5 INHBC GDF3

6.54e-0437863PF00019
DomainTGF_BETA_1

BMP5 INHBC GDF3

6.54e-0437863PS00250
DomainVWC

NELL2 MUC2 SSPOP

7.08e-0438863SM00214
DomainVWFC_2

NELL2 MUC2 SSPOP

7.08e-0438863PS50184
DomainTB

LTBP1 FBN3

7.39e-049862PS51364
DomainTB_dom

LTBP1 FBN3

7.39e-049862IPR017878
DomainNHL_repeat_subgr

TRIM2 TRIM3

7.39e-049862IPR013017
Domain-

TRIM2 LRP2 TRIM3

7.64e-04398632.120.10.30
DomainIG_FLMN

TRIM2 TRIM3

9.21e-0410862SM00557
DomainNHL

TRIM2 TRIM3

9.21e-0410862PF01436
DomainNHL_repeat

TRIM2 TRIM3

9.21e-0410862IPR001258
DomainGalactose-bd-like

PCSK5 LAMB1 EDIL3 SSPOP

9.32e-0494864IPR008979
DomainVWF_dom

NELL2 MUC2 SSPOP

9.50e-0442863IPR001007
DomainFilamin

TRIM2 TRIM3

1.12e-0311862PF00630
DomainEphrin_rec_like

SCUBE1 SCUBE3

1.12e-0311862PF07699
DomainFILAMIN_REPEAT

TRIM2 TRIM3

1.12e-0311862PS50194
DomainFilamin/ABP280_rpt

TRIM2 TRIM3

1.12e-0311862IPR001298
DomainFilamin/ABP280_repeat-like

TRIM2 TRIM3

1.12e-0311862IPR017868
Domain6-blade_b-propeller_TolB-like

TRIM2 LRP2 TRIM3

1.24e-0346863IPR011042
Domainzf-C2H2

ZNF462 IKZF3 ZNF277 ZNF423 ZNF483 ZIM2 ZNF521 IKZF1 ZNF653 PRDM2

1.29e-036938610PF00096
DomainEGF_3

SCUBE1 SCUBE3

1.34e-0312862PF12947
DomainTIL

MUC2 SSPOP

1.34e-0312862PF01826
DomainEGF_dom

SCUBE1 SCUBE3

1.34e-0312862IPR024731
DomainC8

MUC2 SSPOP

1.34e-0312862PF08742
DomainUnchr_dom_Cys-rich

MUC2 SSPOP

1.58e-0313862IPR014853
DomainC8

MUC2 SSPOP

1.58e-0313862SM00832
DomainNHL

TRIM2 TRIM3

1.58e-0313862PS51125
DomainBbox_C

TRIM2 TRIM3

2.12e-0315862IPR003649
DomainBBC

TRIM2 TRIM3

2.12e-0315862SM00502
DomainVWD

MUC2 SSPOP

2.41e-0316862SM00216
DomainVWF_type-D

MUC2 SSPOP

2.41e-0316862IPR001846
DomainVWFD

MUC2 SSPOP

2.41e-0316862PS51233
DomainVWD

MUC2 SSPOP

2.41e-0316862PF00094
DomainZINC_FINGER_C2H2_2

ZNF462 IKZF3 ZNF277 ZNF423 ZNF483 ZIM2 ZNF521 IKZF1 ZNF653 PRDM2

2.93e-037758610PS50157
DomainZINC_FINGER_C2H2_1

ZNF462 IKZF3 ZNF277 ZNF423 ZNF483 ZIM2 ZNF521 IKZF1 ZNF653 PRDM2

2.99e-037778610PS00028
DomainCTCK_1

MUC2 SSPOP

3.06e-0318862PS01185
DomainZnf_C2H2-like

ZNF462 IKZF3 ZNF277 ZNF423 ZNF483 ZIM2 ZNF521 IKZF1 ZNF653 PRDM2

3.55e-037968610IPR015880
Domain-

BMP5 INHBC GDF3

3.65e-03678632.10.90.10
DomainCystine-knot_cytokine

BMP5 INHBC GDF3

3.65e-0367863IPR029034
DomainZnf_C2H2

ZNF462 IKZF3 ZNF277 ZNF423 ZNF483 ZIM2 ZNF521 IKZF1 ZNF653 PRDM2

3.84e-038058610IPR007087
DomainZnF_C2H2

ZNF462 IKZF3 ZNF277 ZNF423 ZNF483 ZIM2 ZNF521 IKZF1 ZNF653 PRDM2

3.94e-038088610SM00355
DomainBBOX

TRIM2 TRIM31 TRIM3

3.97e-0369863SM00336
DomainLIM

LIMK2 LIMS1 LIMS2

3.97e-0369863PF00412
Domain-

ZNF462 IKZF3 ZNF423 ZNF483 ZIM2 ZNF521 IKZF1 ZNF653 PRDM2

4.00e-036798693.30.160.60
Domain-

LIMK2 LIMS1 LIMS2

4.13e-03708632.10.110.10
DomainFA58C

EDIL3 SSPOP

4.16e-0321862SM00231
DomainFA58C_3

EDIL3 SSPOP

4.16e-0321862PS50022
DomainFA58C_1

EDIL3 SSPOP

4.16e-0321862PS01285
DomainFA58C_2

EDIL3 SSPOP

4.16e-0321862PS01286
DomainZnf_LIM

LIMK2 LIMS1 LIMS2

4.30e-0371863IPR001781
DomainLIM_DOMAIN_1

LIMK2 LIMS1 LIMS2

4.30e-0371863PS00478
DomainLIM_DOMAIN_2

LIMK2 LIMS1 LIMS2

4.30e-0371863PS50023
Domain-

TRIM2 TRIM31 TRIM3

4.30e-03718634.10.45.10
DomainLIM

LIMK2 LIMS1 LIMS2

4.30e-0371863SM00132
Domainzf-B_box

TRIM2 TRIM31 TRIM3

4.47e-0372863PF00643
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 OR4C12 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16

1.30e-093897415M14091
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 OR4C12 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16

3.35e-094177415M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 LRP2 OR6Y1 OR5A2 OR4C13 OR4C12 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16

1.43e-076367416M41834
Pubmed

The human olfactory receptor gene family.

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR5A2 OR4C13 OR4C12 OR2T12 OR4X1 OR10T2 OR56B4 OR14A16 OR4A4P

7.02e-13541901614983052
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR4C13 OR4C12 OR2T12 OR56B4 OR4A4P

8.69e-11340901211875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR4C13 OR4C12 OR2T12 OR56B4 OR4A4P

8.69e-11340901211802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR4C13 OR4C12 OR2T12 OR56B4 OR4A4P

9.61e-11343901232295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR4C3 OR5M9 OR7C2 OR11A1 OR4A47 OR1E2 OR6Y1 OR4C13 OR4C12 OR2T12 OR56B4 OR4A4P

1.06e-10346901214611657
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR5M9 OR7C2 OR4A47 OR1E2 OR5A2 OR4C13 OR4C12 OR4A4P

1.08e-0721990812213199
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

PCSK5 NELL2 ZNF277 ZNF423 MATN2 APBB1 LRP2 LAMB1 LTBP1 SSPOP DKK3

5.09e-07608901116713569
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR5M9 OR7C2 OR1E2 OR6Y1 OR56B4

1.45e-067490515081110
Pubmed

IKZF1/3 and CRL4CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma.

IKZF3 IKZF1

6.62e-06290231558666
Pubmed

Signaling via PINCH: Functions, binding partners and implications in human diseases.

LIMS1 LIMS2

6.62e-06290227590440
Pubmed

A variant in human AIOLOS impairs adaptive immunity by interfering with IKAROS.

IKZF3 IKZF1

6.62e-06290234155405
Pubmed

Focal adhesion proteins Pinch1 and Pinch2 regulate bone homeostasis in mice.

LIMS1 LIMS2

6.62e-06290231723057
Pubmed

Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia.

IKZF3 IKZF1

6.62e-06290224509510
Pubmed

Role of Aiolos and Ikaros in the Antitumor and Immunomodulatory Activity of IMiDs in Multiple Myeloma: Better to Lose Than to Find Them.

IKZF3 IKZF1

6.62e-06290233499314
Pubmed

LIM domain proteins Pinch1/2 regulate chondrogenesis and bone mass in mice.

LIMS1 LIMS2

6.62e-06290233083097
Pubmed

A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones.

SCUBE1 SCUBE3

6.62e-06290215234972
Pubmed

TRIM31 promotes proliferation, invasion and migration of glioma cells through Akt signaling pathway.

TRIM31 TRIM3

6.62e-06290231129970
Pubmed

Notch signalling regulates asymmetric division and inter-conversion between lgr5 and bmi1 expressing intestinal stem cells.

POFUT1 LGR5

6.62e-06290227181744
Pubmed

Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation.

IKZF3 IKZF1

6.62e-0629029155026
Pubmed

Suppression of Aiolos and Ikaros expression by lenalidomide reduces human ILC3-ILC1/NK cell transdifferentiation.

IKZF3 IKZF1

6.62e-06290231151137
Pubmed

Impaired tissue homing by the Ikzf3N159S variant is mediated by interfering with Ikaros function.

IKZF3 IKZF1

6.62e-06290237662955
Pubmed

Trans-Ancestral Fine-Mapping and Epigenetic Annotation as Tools to Delineate Functionally Relevant Risk Alleles at IKZF1 and IKZF3 in Systemic Lupus Erythematosus.

IKZF3 IKZF1

6.62e-06290233182226
Pubmed

Critical function of Ikaros in controlling Aiolos gene expression.

IKZF3 IKZF1

6.62e-06290217383641
Pubmed

High IKZF1/3 protein expression is a favorable prognostic factor for survival of relapsed/refractory multiple myeloma patients treated with lenalidomide.

IKZF3 IKZF1

6.62e-06290227881177
Pubmed

Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.

LIMK2 LGR5

6.62e-06290223585469
Pubmed

Can signal peptide-CUB-EGF domain-containing protein (SCUBE) levels be a marker of angiogenesis in patients with psoriasis?

SCUBE1 SCUBE3

6.62e-06290228238185
Pubmed

Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Krüppel-like zinc finger protein.

ZNF423 ZNF521

6.62e-06290212393497
Pubmed

Requirement for PINCH in skeletal myoblast differentiation.

LIMS1 LIMS2

6.62e-06290236385586
Pubmed

Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis.

LIMS1 LIMS2

6.62e-06290224058607
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

PCSK5 NELL2 MATN2 LAMB1 LTBP1

1.44e-0511890521078624
Pubmed

PDGFRα controls the balance of stromal and adipogenic cells during adipose tissue organogenesis.

ZNF423 ZNF521 EDIL3

1.58e-051990328049691
Pubmed

Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network.

PCSK5 SCUBE1 OAS3

1.58e-051990323149075
Pubmed

Characterization of PINCH-2, a new focal adhesion protein that regulates the PINCH-1-ILK interaction, cell spreading, and migration.

LIMS1 LIMS2

1.98e-05390212167643
Pubmed

Direct transcriptional repression of Zfp423 by Zfp521 mediates a bone morphogenic protein-dependent osteoblast versus adipocyte lineage commitment switch.

ZNF423 ZNF521

1.98e-05390224891617
Pubmed

Intrinsic transition of embryonic stem-cell differentiation into neural progenitors.

ZNF521 EP300

1.98e-05390221326203
Pubmed

The relationship of serum SCUBE-1, -2 and -3 levels with clinical findings and ultrasonographic skin thickness in systemic sclerosis patients.

SCUBE1 SCUBE3

1.98e-05390231991528
Pubmed

ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies.

ZNF423 ZNF521

1.98e-05390226788497
Pubmed

POFUT1 and PLAGL2 are characteristic markers of mucinous colorectal cancer associated with MUC2 expression.

POFUT1 MUC2

1.98e-05390238500386
Pubmed

Identification of a novel family of cell-surface proteins expressed in human vascular endothelium.

SCUBE1 SCUBE3

1.98e-05390212270931
Pubmed

Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemia.

IKZF3 IKZF1

1.98e-05390211937265
Pubmed

Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors.

IKZF3 IKZF1

1.98e-0539029560339
Pubmed

Analysis of Ikaros family splicing variants in human hematopoietic lineages.

IKZF3 IKZF1

1.98e-05390220432734
Pubmed

Expression patterns of Ikaros family members during positive selection and lineage commitment of human thymocytes.

IKZF3 IKZF1

1.98e-05390227502439
Pubmed

Brief research report: Effects of Pinch deficiency on cartilage homeostasis in adult mice.

LIMS1 LIMS2

1.98e-05390236743414
Pubmed

Consequences of loss of PINCH2 expression in mice.

LIMS1 LIMS2

1.98e-05390216317048
Pubmed

The CD8alpha gene locus is regulated by the Ikaros family of proteins.

IKZF3 IKZF1

1.98e-05390212504015
Pubmed

Megalin interacts with APP and the intracellular adapter protein FE65 in neurons.

APBB1 LRP2

1.98e-05390220637285
Pubmed

Aberrant Ikaros, Aiolos, and Helios expression in Hodgkin and non-Hodgkin lymphoma.

IKZF3 IKZF1

1.98e-05390218332232
Pubmed

Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.

NELL2 CTTNBP2 ZNF423 LTBP1 SMTN

3.28e-0514090526930384
Pubmed

The matrilins: a growing family of A-domain-containing proteins.

MATN2 MATN4

3.96e-05490210830110
Pubmed

Characterization of the matrilin coiled-coil domains reveals seven novel isoforms.

MATN2 MATN4

3.96e-05490211896063
Pubmed

Molecular structure, processing, and tissue distribution of matrilin-4.

MATN2 MATN4

3.96e-05490211279097
Pubmed

Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis.

MATN2 MATN4

3.96e-05490231963938
Pubmed

Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.).

IKZF3 IKZF1

3.96e-05490224328678
Pubmed

Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity.

NR1I2 EP300

3.96e-05490226855179
Pubmed

A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading.

LIMS1 LIMS2

3.96e-05490211331308
Pubmed

The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins.

IKZF3 IKZF1

3.96e-05490224292623
Pubmed

TRIM-NHL proteins in development and disease.

TRIM2 TRIM3

3.96e-05490226514622
Pubmed

Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.

BRD1 EP300

3.96e-05490235716662
Pubmed

Expression of matrilins during maturation of mouse skeletal tissues.

MATN2 MATN4

3.96e-05490212009334
Pubmed

KLF4 deletion alters gastric cell lineage and induces MUC2 expression.

LGR5 MUC2

3.96e-05490227277677
Pubmed

Functional interactions between ubiquitin E2 enzymes and TRIM proteins.

TRIM2 TRIM31 TRIM3

4.69e-052790321143188
Pubmed

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.

CTTNBP2 MATN4 LTBP1

5.24e-052890333953184
Pubmed

Macrophage PPARγ, a Lipid Activated Transcription Factor Controls the Growth Factor GDF3 and Skeletal Muscle Regeneration.

GDF3 EDIL3

6.59e-05590227836432
Pubmed

Scube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouse.

SCUBE1 SCUBE3

6.59e-05590223383134
Pubmed

A histone methyltransferase is required for maximal response to female sex hormones.

EP300 PRDM2

6.59e-05590215282304
Pubmed

Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity.

IKZF3 IKZF1

6.59e-05590210766745
Pubmed

Cyclin O (Ccno) functions during deuterosome-mediated centriole amplification of multiciliated cells.

EDIL3 DNAH5

6.59e-05590225712475
Pubmed

Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.

IKZF3 IKZF1

6.59e-05590210978333
Pubmed

Early hematopoietic zinc finger protein (EHZF), the human homolog to mouse Evi3, is highly expressed in primitive human hematopoietic cells.

ZNF423 ZNF521

6.59e-05590214630787
Pubmed

Dissecting integrin-dependent regulation of neural stem cell proliferation in the adult brain.

LIMS1 LIMS2

6.59e-05590224719101
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

MATN2 LAMB1 MATN4 LTBP1 MUC2

7.60e-0516790522159717
Pubmed

PINCH2 is a new five LIM domain protein, homologous to PINCHand localized to focal adhesions.

LIMS1 LIMS2

9.87e-05690212651156
Pubmed

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.

APBB1 LRP2

9.87e-0569029837937
Pubmed

Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.

PCSK5 EDIL3

9.87e-05690228446132
Pubmed

Ikaros and Aiolos inhibit pre-B-cell proliferation by directly suppressing c-Myc expression.

IKZF3 IKZF1

9.87e-05690220566697
Pubmed

Lipopolysaccharide modulates p300 and Sirt1 to promote PRMT1 stability via an SCFFbxl17-recognized acetyldegron.

FBXL17 EP300

9.87e-05690228883095
Pubmed

Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity.

LGR5 MUC2 DKK3

1.12e-043690327736991
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

PCSK5 LRP2 LTBP1 DNAH5

1.36e-0410090425807483
Pubmed

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.

BMP5 INHBC DLL3 GDF3

1.36e-0410090424859004
Pubmed

Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4.

MATN2 MATN4

1.38e-04790227573814
Pubmed

The primitive endoderm segregates from the epiblast in β1 integrin-deficient early mouse embryos.

LRP2 EDIL3

1.38e-04790224277939
Pubmed

Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation.

LGR5 EDIL3

1.38e-04790231130414
Pubmed

Aiolos collaborates with Blimp-1 to regulate the survival of multiple myeloma cells.

IKZF3 IKZF1

1.38e-04790226823144
Pubmed

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes.

IKZF3 IKZF1

1.38e-04790210357820
Pubmed

Disruption of Scube2 Impairs Endochondral Bone Formation.

SCUBE1 SCUBE3

1.38e-04790225639508
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

PRKD2 NELL2 LIMK2 ZC3H4 WRNIP1 LRP2 LAMB1 OAS3 XYLB BRD1 EP300

1.45e-041116901131753913
Pubmed

The tripartite motif family identifies cell compartments.

TRIM2 TRIM31 TRIM3

1.66e-044190311331580
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

DLL3 POFUT1 MUC2

1.66e-044190322675208
Pubmed

Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice.

LIMS1 LIMS2

1.84e-04890223658024
Pubmed

Mouse kalinin B1 (laminin beta 3 chain): cloning and tissue distribution.

LAMB1 CR1

1.84e-0489027898049
Pubmed

Cdx2 determines the fate of postnatal intestinal endoderm.

LGR5 EDIL3

1.84e-04890222190642
Pubmed

Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.

OR6Y1 OR2T12 OR14A16

2.35e-044690332126975
Pubmed

The extracellular-matrix protein matrilin 2 participates in peripheral nerve regeneration.

MATN2 MATN4

2.36e-04990219295126
Pubmed

Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities.

MATN2 MATN4

2.36e-04990215296947
Pubmed

Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development.

IKZF3 IKZF1

2.36e-04990219734904
Pubmed

Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.

IKZF3 NR1I2 EP300 PRDM2

2.49e-0411790419124506
Pubmed

Functional consequences of cell type-restricted expression of laminin α5 in mouse placental labyrinth and kidney glomerular capillaries.

LAMB1 EDIL3

2.94e-041090222911783
Pubmed

A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1.

PCGF2 ZNF277

2.94e-041090220808772
Pubmed

Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis.

MATN2 MATN4

2.94e-041090216877353
InteractionSCUBE3 interactions

SCUBE1 MATN2 SCUBE3

3.08e-068783int:SCUBE3
CytobandEnsembl 112 genes in cytogenetic band chr11p11

OR4C3 OR4A47 OR4C13 OR4C12 EXT2 OR4X1

6.14e-07153906chr11p11
Cytoband11p11.12

OR4C13 OR4C12 OR4A4P

7.91e-054290311p11.12
Cytoband12q24.2

CAMKK2 OAS3

4.48e-041690212q24.2
Cytoband11p11.2

OR4C3 OR4A47 OR4X1

5.98e-048390311p11.2
GeneFamilyOlfactory receptors, family 4

OR4C3 OR4A47 OR4C13 OR4C12 OR4X1 OR4A4P

5.20e-06129626151
GeneFamilyLIM zinc finger domain containing|LIM domain containing

LIMS1 LIMS2

6.91e-0546221163
CoexpressionNABA_ECM_GLYCOPROTEINS

NELL2 MATN2 LAMB1 MATN4 LTBP1 EDIL3 SSPOP FBN3

2.07e-07196838M3008
CoexpressionNABA_MATRISOME

PCSK5 BMP5 NELL2 SCUBE1 INHBC MATN2 SCUBE3 LAMB1 MATN4 LTBP1 GDF3 EDIL3 MUC2 SSPOP FBN3

7.06e-0710268315M5889
CoexpressionNABA_ECM_GLYCOPROTEINS

NELL2 MATN2 LAMB1 MATN4 LTBP1 EDIL3 SSPOP

2.54e-06191837MM17059
CoexpressionNABA_CORE_MATRISOME

NELL2 MATN2 LAMB1 MATN4 LTBP1 EDIL3 SSPOP FBN3

2.65e-06275838M5884
CoexpressionNABA_MATRISOME

PCSK5 BMP5 NELL2 SCUBE1 INHBC MATN2 SCUBE3 LAMB1 MATN4 LTBP1 GDF3 EDIL3 MUC2 SSPOP

3.16e-0610088314MM17056
CoexpressionNABA_CORE_MATRISOME

NELL2 MATN2 LAMB1 MATN4 LTBP1 EDIL3 SSPOP

2.43e-05270837MM17057
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BMP5 MATN2 ZIM2 ZNF521 LAMB1 LTBP1 LGR5 DKK3

5.09e-0919787844673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SEC16B BMP5 SCUBE1 MATN2 SCUBE3 LTBP1 DKK3

1.29e-07199877fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BMP5 ZNF423 ZNF521 LAMB1 LTBP1 LGR5 DKK3

1.34e-07200877fb53be20392a8309a7393774c774a1b1aec6e676
ToppCellControl-Myeloid-Mast|Control / Disease state, Lineage and Cell class

ZNF462 IKZF3 CTTNBP2 ZNF521 SLC38A11 EDIL3

1.04e-061708769a14deb7f7cd4a49c217eba4023f7bf1dec6c902
ToppCellControl-Myeloid-Mast|World / Disease state, Lineage and Cell class

ZNF462 IKZF3 CTTNBP2 ZNF521 SLC38A11 EDIL3

1.08e-06171876ed8e61d524f4cddc6084b261175df54d2a64a60f
ToppCellControl-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

ZNF462 IKZF3 CTTNBP2 ZNF521 SLC38A11 EDIL3

1.28e-061768760c5916d63e1ada09105e46d2429b75129b7329ec
ToppCellwk_08-11-Mesenchymal-Chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

BMP5 AOPEP ZIM2 ZNF521 MATN4 LTBP1

1.28e-061768761af28b701c4598ce761f85adbd5d79e4918d265a
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMP5 AOPEP LAMB1 LTBP1 EDIL3 SMTN

1.60e-06183876af8d86f15a549064530d94bd47081daf59d58ecd
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

AOPEP ZIM2 SCUBE3 MATN4 EDIL3 DKK3

1.87e-06188876c9270517e6940e9793586f67f02431210552f278
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMP5 AOPEP LAMB1 LTBP1 EDIL3 SMTN

2.18e-06193876146e8c148478ab61b1c1dbaf1ee98a8cd4a0ff8a
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCUBE1 ZNF521 LTBP1 GDF3 EDIL3 LIMS2

2.18e-06193876daefbfd3a3dd1351fbe94b9abfd807db44d56c24
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)|356C / Donor, Lineage, Cell class and subclass (all cells)

AOPEP SCUBE3 LTBP1 EDIL3 DKK3 SMTN

2.38e-06196876a5cc4f76e1a3825aaccba9a686d7da6f7e4300ff
ToppCell(5)_Fibroblast-K_(Pericytes)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

AOPEP SCUBE3 LTBP1 EDIL3 DKK3 SMTN

2.38e-06196876e3c89c5bd674289738d5590ebfd30c605f5156a5
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)-|356C / Donor, Lineage, Cell class and subclass (all cells)

AOPEP SCUBE3 LTBP1 EDIL3 DKK3 SMTN

2.38e-06196876476812fc1422aca8010d771eff11fa6081f15a2d
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCUBE1 MATN2 SCUBE3 LAMB1 LTBP1 DKK3

2.46e-061978762cb1f557ce1400398975de94638126b4522567f3
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMP5 AOPEP SCUBE3 LAMB1 EDIL3 DNAH5

2.53e-061988764a4566f86c9365a41b4cfd1609eac09bd73b3f34
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NELL2 SCUBE1 AOPEP LTBP1 DKK3 SMTN

2.53e-06198876e9f434bfd072e590fe44d518057ee5aa653038f3
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NELL2 SCUBE1 LTBP1 EDIL3 SMTN LIMS2

2.53e-0619887622e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)|390C / Donor, Lineage, Cell class and subclass (all cells)

AOPEP LTBP1 EDIL3 DKK3 SMTN LIMS2

2.53e-06198876c82a151f9f1477d4a401457173b8d72af776c137
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)-|390C / Donor, Lineage, Cell class and subclass (all cells)

AOPEP LTBP1 EDIL3 DKK3 SMTN LIMS2

2.53e-06198876dc63b56bb6291e527b172d603569376286262845
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

AOPEP SCUBE3 LTBP1 EDIL3 SMTN LIMS2

2.60e-06199876056a28c36cd58dc695a5ae6f29b62135d6aad819
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

AOPEP SCUBE3 LTBP1 EDIL3 SMTN LIMS2

2.60e-06199876534dcfe8b65ad92bb8d749d1c7036ad4807e09cd
ToppCellILEUM-non-inflamed-(8)_Smooth_muscle_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

BMP5 AOPEP LAMB1 LTBP1 EDIL3 SMTN

2.60e-061998763368c0a90a47c4dcdfe70be3192550df0744e508
ToppCellproximal-mesenchymal-Fibromyocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SCUBE1 AOPEP LTBP1 EDIL3 DKK3 SMTN

2.68e-0620087637d9f46f727a31e8e94e348e4ddd71a2125ba01a
ToppCellproximal-3-mesenchymal-Fibromyocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SCUBE1 AOPEP LTBP1 EDIL3 DKK3 SMTN

2.68e-06200876ed6fbe61a04d29b105054f7058abe7469314b304
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ZNF462 PCSK5 MATN2 LAMB1 LTBP1 DKK3

2.68e-0620087609537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

BMP5 MATN2 LAMB1 LTBP1 LGR5 DKK3

2.68e-06200876efdf7066b7dd43e35dbc0d2719b75f250cf54af2
ToppCellproximal-mesenchymal-Fibromyocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SCUBE1 AOPEP LTBP1 EDIL3 DKK3 SMTN

2.68e-0620087649658e1b530de0dad16d45a1112bdf5329bb800d
ToppCell(5)_Fibroblast-B_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

BMP5 AOPEP LAMB1 LTBP1 EDIL3 DKK3

2.68e-062008769bbaa666d0f3b4782c1b4b95e0fa5fc1467842d8
ToppCellIIH-CD8-proli_CD4|IIH / Condition, Cell_class and T cell subcluster

NELL2 LAMB1 XYLB DKK3 TRIM3

1.00e-051468757fa6e35def3f7cffbee1e1c2f10b523bab678e14
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CTTNBP2 ZNF423 ZNF521 GDF3 SSPOP

1.86e-05166875c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCellInfluenza_Severe-CD4+_Tcm|Influenza_Severe / Disease group and Cell class

NELL2 MATN2 ZNF483 TRIM31 IL23R

2.21e-0517287547865a04968ca28c6ff125159d9a23e37c8b8af1
ToppCellfacs-Aorta|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 EDIL3 DNAH5 SSPOP LIMS2

2.47e-051768750b3491451be02c18a16cdb875645be47eb867a7f
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SCUBE1 CTTNBP2 LTBP1 OR2T12 SMTN

2.53e-05177875b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCUBE1 CTTNBP2 LAMB1 LTBP1 DKK3

2.82e-05181875b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellwk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SEC16B ZIM2 SCUBE3 MATN4 EDIL3

2.90e-0518287500a148b1e499bf16325491536d187d4dd6b70c06
ToppCellBasal|World / shred by cell class for mouse tongue

AOPEP MATN2 LAMB1 LTBP1 DKK3

2.97e-05183875c6729a207526ff4aa48176207b9353176f631fea
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMP5 AOPEP LTBP1 SMTN LIMS2

2.97e-051838756b5eef96b28911c752a8b6c0975918c4572cec38
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 CTTNBP2 LTBP1 RP1 LIMS2

3.21e-051868752d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

BMP5 ZNF521 LAMB1 LTBP1 DKK3

3.30e-05187875bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellnormal_Lung-Fibroblasts-Smooth_muscle_cells|normal_Lung / Location, Cell class and cell subclass

AOPEP LTBP1 EDIL3 DKK3 SMTN

3.38e-05188875fd70fb89570f014d1299c60fe017dc09f24e57c6
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMP5 SCUBE1 CTTNBP2 LAMB1 DNAH5

3.38e-05188875997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF462 MATN2 APBB1 DKK3 SMTN

3.47e-05189875d00410010283dc6191ce9857d6c7952678fed588
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NELL2 LIMS1 CAMKK2 DKK3 SMTN

3.56e-051908759ce301841ce9486701fa28eb2a9929e35d476878
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 CTTNBP2 LTBP1 RP1 LIMS2

3.56e-05190875aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF462 CTTNBP2 LAMB1 EDIL3 DNAH5

3.65e-05191875d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 BMP5 LGR5 DKK3 SMTN

3.65e-05191875fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP5 AOPEP LAMB1 LTBP1 DKK3

3.65e-05191875d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP5 AOPEP LAMB1 LTBP1 DKK3

3.65e-05191875de3e9b704621b26836c2ddc39fa3e840dfb4541b
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF423 LTBP1 SLC38A11 SMTN LIMS2

3.74e-05192875fee99ca7e658963acf968aa724ef8c96cfc00a5d
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZNF521 LAMB1 LTBP1 EDIL3 DKK3

3.74e-0519287567e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NELL2 LIMS1 CTTNBP2 DKK3 SMTN

3.74e-05192875d43caf42ec744e895137f31ef65a990e250669d2
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)|368C / Donor, Lineage, Cell class and subclass (all cells)

AOPEP SCUBE3 EDIL3 DKK3 SMTN

3.83e-051938755182284dfa7c94027e94172e08f78c86b95d63f4
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP5 MATN2 LAMB1 LTBP1 DKK3

3.83e-05193875d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCellILEUM-inflamed-(8)_Smooth_muscle_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

BMP5 AOPEP LAMB1 LTBP1 EDIL3

3.83e-05193875084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

BMP5 ZNF521 LAMB1 LTBP1 DKK3

3.83e-05193875e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)-|368C / Donor, Lineage, Cell class and subclass (all cells)

AOPEP SCUBE3 EDIL3 DKK3 SMTN

3.83e-051938754f7bab0115469c855160636d168bd6e5d4e2dd2f
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCUBE1 LTBP1 EDIL3 DKK3 SMTN

3.93e-0519487591205b22650e7ecdb72bb59348ce2530b76c532c
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

BMP5 ZNF521 LAMB1 LTBP1 DKK3

3.93e-0519487503a269f75a481ea54aea8e6444605db8d6df493d
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCUBE1 LTBP1 EDIL3 DKK3 SMTN

3.93e-051948756e12a7da35be4c0ecf998ef94b8989b89d74b200
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCUBE1 LTBP1 EDIL3 DKK3 SMTN

3.93e-05194875c52f10140c66e8c0566421c3d535d5d92bf595e1
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PCSK5 SCUBE1 AOPEP LTBP1 SMTN

4.02e-051958754dba732c8d8ecf0ed9ece1814dc4060402199ed9
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-MYL4+_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

AOPEP MATN2 LTBP1 SMTN LIMS2

4.02e-05195875dba2a87efd7e067c094c4b367feb4138cab62735
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

AOPEP MATN2 LGR5 EDIL3 DKK3

4.02e-0519587578978d85273e5463a7f43e4c121e647fa6aba42b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BMP5 MATN2 LAMB1 LTBP1 DKK3

4.02e-051958751236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCelltumor_Lung-Fibroblasts-Smooth_muscle_cells|tumor_Lung / Location, Cell class and cell subclass

AOPEP LTBP1 EDIL3 DKK3 SMTN

4.02e-05195875ea9ff25020c2fcd1bab80e1829af0f4e4777de8b
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 LRP2 LAMB1 LTBP1 DNAH5

4.12e-051968756bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 LRP2 LAMB1 LTBP1 DNAH5

4.12e-05196875c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NELL2 SCUBE1 LTBP1 EDIL3 SMTN

4.12e-051968755159d8625d80c20eb28157b2603c8bde9d377a35
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BMP5 MATN2 LTBP1 LGR5 DKK3

4.12e-05196875e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCellPericytes|World / shred by cell class for parenchyma

SCUBE3 LTBP1 EDIL3 DKK3 SMTN

4.12e-051968758e7ecbe77d312a7fc6aadd8fd52c13dd1834cc7e
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BMP5 MATN2 LTBP1 LGR5 DKK3

4.12e-0519687582fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCell11.5-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

PCSK5 AOPEP MATN2 LTBP1 SMTN

4.12e-0519687505530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SCUBE1 ZNF521 GDF3 EDIL3 LIMS2

4.12e-0519687595c5b8fd4ebfae1f42de9b1475c1161d4a80e515
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMP5 MATN2 LAMB1 EDIL3 DKK3

4.12e-051968752ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell15-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

PCSK5 AOPEP MATN2 LTBP1 SMTN

4.12e-051968750e45817625b96d21a8cc4dfbbd465ee6403b6802
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 LTBP1 EDIL3 DKK3 SMTN

4.12e-051968758c25fa61c117a60ddd4cbd2f95ae5b66f986a1ec
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NELL2 SCUBE1 LTBP1 EDIL3 SMTN

4.12e-051968756b5b7dbcb2cce8a736e44145a01290905876a5e9
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BMP5 MATN2 LTBP1 LGR5 DKK3

4.12e-0519687585e5046f774537684e1443c0fc147d562b7068d0
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NELL2 SCUBE1 LTBP1 EDIL3 SMTN

4.12e-051968759830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK5 ZNF521 LTBP1 LGR5 DKK3

4.22e-051978750dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

BMP5 ZNF521 LAMB1 LTBP1 EDIL3

4.22e-05197875f1c8936986123a3151140c374fcd62d6705c530b
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CTTNBP2 ZNF521 LAMB1 GDF3 SMTN

4.22e-051978754e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMP5 AOPEP SCUBE3 EDIL3 DNAH5

4.22e-051978752e3d64648a1e4f01b9256a96b94b8a640ee1824c
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMP5 SCUBE3 LAMB1 EDIL3 DNAH5

4.22e-051978751da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCell(2)_Fibroblasts-(22)_Fibro-3|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

PCSK5 BMP5 CTTNBP2 MATN4 EDIL3

4.22e-05197875d9021bab82403e566ec10f78acb227c0f80b88fe
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP5 SCUBE1 AOPEP EDIL3 DKK3

4.22e-051978754b6c0e028b9669c102df8e9dc63e284f8d5fd9ee
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-MYL4+_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

AOPEP SCUBE3 LTBP1 SMTN LIMS2

4.22e-051978754797f414330316e2ac2cf7cd2570d991877d7a38
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP5 SCUBE1 AOPEP EDIL3 DKK3

4.22e-05197875ece0c17eb68f394b20e588c0b0626d3987a4dbbb
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)|343B / Donor, Lineage, Cell class and subclass (all cells)

SCUBE3 LTBP1 EDIL3 DKK3 SMTN

4.22e-0519787578d45d11820ec379942c4c3defd619d5f8cc8e1f
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SCUBE3 LTBP1 EDIL3 DKK3 SMTN

4.22e-0519787531bc9fd679d78550541d4158568e8dd09ff29e8e
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

BMP5 ZNF521 LAMB1 LTBP1 DKK3

4.22e-05197875f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCelltumor_Lung-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

AOPEP LTBP1 EDIL3 SMTN LIMS2

4.33e-05198875f540f464118edc0fb809ebcb813d0302e6952253
ToppCellTracheal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 CTTNBP2 ZNF521 IKZF1 SLC38A11

4.33e-05198875cc5ca64749e2f4f1d373d9472824df85741702b7
ToppCelltumor_Lung-Fibroblasts-Myofibroblasts|tumor_Lung / Location, Cell class and cell subclass

AOPEP LAMB1 LTBP1 EDIL3 DKK3

4.33e-0519887531f9181dab689aabe9c6182c2ef7de65ba3f0ff6
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

BMP5 SCUBE1 LAMB1 LTBP1 DKK3

4.33e-05198875300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-CD4+_Tem|Bac-SEP / Disease, condition lineage and cell class

NELL2 TRIM2 FMO4 DLL3 IL23R

4.33e-05198875292b26f316f016b50d07689f84772eec46060251
ToppCellTracheal-10x5prime-Stromal-Chondrocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

BMP5 MATN2 SCUBE3 MATN4 EDIL3

4.33e-05198875c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

BMP5 LIMS1 LAMB1 EDIL3 DKK3

4.33e-05198875e0e47cf65774191981840b22905b2094b95abe0f
ToppCellTracheal-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IKZF3 CTTNBP2 ZNF521 IKZF1 SLC38A11

4.33e-05198875d4d66f19df078bfc3a83d4664aaf9c7789bde1a5
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A

CFLAR BMP5 NELL2 INHBC IKZF1 POFUT1 SNAPC3

8.99e-061928775216_UP
DrugTheobromine [83-67-0]; Down 200; 22.2uM; MCF7; HT_HG-U133A

CFLAR LIMK2 FMO4 LRP2 IKZF1 POFUT1 TRIM3

1.06e-051978773334_DN
Drugrottlerin; Down 200; 10uM; MCF7; HT_HG-U133A_EA

CFLAR BMP5 CAMKK2 FMO4 SNAPC3 TRIM3 SMTN

1.10e-05198877914_DN
Drugtolbutamide; Down 200; 100uM; MCF7; HG-U133A

CFLAR FMO4 IKZF1 LTBP1 KLHDC10 PRDM2 LIMS2

1.13e-05199877142_DN
Diseaseautosomal recessive limb-girdle muscular dystrophy (implicated_via_orthology)

TRIM2 TRIM3

2.57e-053872DOID:0110274 (implicated_via_orthology)
Diseaseautosomal recessive limb-girdle muscular dystrophy type 2H (implicated_via_orthology)

TRIM2 TRIM3

2.57e-053872DOID:0110282 (implicated_via_orthology)
DiseaseCCL2 measurement

LIMS1 ZC3H4 FBXL17 CCR3

5.37e-04126874EFO_0004749
Diseaseeosinophil percentage of granulocytes

LIMK2 IKZF3 TRIM31 CCR3 IKZF1

6.55e-04234875EFO_0007996
DiseasePrecursor Cell Lymphoblastic Leukemia Lymphoma

IKZF3 IKZF1 EP300

7.87e-0461873C1961102
DiseaseUlcerative Colitis

LAMB1 IKZF1 IL23R

8.65e-0463873C0009324
DiseaseGastro-enteropancreatic neuroendocrine tumor

IKZF3 IKZF1

8.80e-0415872C2930967
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

PCSK5 DNAH5

1.42e-0319872DOID:9562 (implicated_via_orthology)
Diseasemuscular dystrophy (implicated_via_orthology)

TRIM2 TRIM3

1.74e-0321872DOID:9884 (implicated_via_orthology)
Diseaseidiopathic pulmonary fibrosis (is_marker_for)

CFLAR EP300

2.09e-0323872DOID:0050156 (is_marker_for)
Diseasecoffee consumption measurement

PRKD2 SEC16B ZC3H4 LIMS2

2.09e-03182874EFO_0006781
Diseaseankylosing spondylitis

PCSK5 EDIL3 IL23R

2.49e-0391873EFO_0003898

Protein segments in the cluster

PeptideGeneStartEntry
LCFFGMHVQEYGSDC

EP300

1371

Q09472
MCNLAVHQECYGVPY

BRD1

236

O95696
FAFIMAAGPASFCCH

APBB1

621

O00213
GVCSHMEYPCRFQNA

AOPEP

376

Q8N6M6
AAYLADMSFELPCHC

FAM187A

41

A6NFU0
AHFSGLVCACAPGYM

DLL3

446

Q9NYJ7
FECECFPGYESGFML

FBN3

1051

Q75N90
FACMPEHRDYDSFVC

CFLAR

296

O15519
VAAGHDCCPMLFNYD

ARPC1A

261

Q92747
GPNHIDQFYCDFMLF

OR11A1

171

Q9GZK7
FCGPNVIGHFMCDLY

OR4C12

166

Q96R67
YCGAHEIDHFFCEAP

OR2T12

166

Q8NG77
RKYCEHDFQMLFAPC

LIMS2

61

Q7Z4I7
PGCEHECVNMEESYY

MATN2

411

O00339
MFHCTCNPGYKLAAD

MATN4

236

O95460
FGDNNRMTYFCPHCQ

NEIL3

266

Q8TAT5
CECRDGYHDNGMFSP

NELL2

581

Q99435
AGEFKYHPECFACMS

LIMK2

86

P53671
YAMNFCIGQCPLHIA

INHBC

271

P55103
KGFMANYCHGECPFS

GDF3

286

Q9NR23
HSFCNYMGFPAVCAA

RCE1

261

Q9Y256
DMCHQSCPRGFYADS

PCSK5

1351

Q92824
FHCAAVTPAGCMYIH

KLHDC10

366

Q6PID8
EGSYNCFCTHPMVLD

LTBP1

1486

Q14766
FCGPNVIDHFFCDMY

OR4A47

166

Q6IF82
FCGPNIMDHYFCDVH

OR4X1

166

Q8NH49
QHDFCGPYMINHFFC

OR5A2

166

Q8NGI9
QHYYDACVFDSCFMP

MUC2

4711

Q02817
NVCKEMSCYSDFPFH

FMO4

61

P31512
FAFEEAIGYMCCPFV

PGM2

421

Q96G03
YRAPAFCDHCGEMLF

PRKD2

146

Q9BZL6
GLNCELCMDFYHDLP

LAMB1

306

P07942
FPDGAYCQATMFECK

LRP2

3836

P98164
FRDPFECNMCGYHSQ

IKZF1

486

Q13422
YHFNVMTCEGCKGFF

NR1I2

51

O75469
FCGPNVIDHFMCDLY

OR4C13

166

Q8NGP0
DMRFCGPNRVNHYFC

OR10T2

166

Q8NGX3
ELNPHLMCALCGGYF

PCGF2

11

P35227
PMCFAQIYAIHCFFC

OR56B4

101

Q8NH76
DLVANYSCECPGEFM

EDIL3

136

O43854
YSHCCMNPVIYAFVG

CCR3

291

P51677
AHRYFLMDCAGICSP

C18orf15

161

Q96N68
DHYCKEVNCSFPLFM

CR1

1901

P17927
CYYFHENCFLMGTIA

CTTNBP2

1236

Q8WZ74
FAEHCPELQYVGFMG

FBXL17

511

Q9UF56
NFLEPHASMYCTAEC

IL23R

91

Q5VWK5
YCDGECSFPLNAHMN

BMP5

381

P22003
YCFVFGQCPFMDERI

CAMKK2

381

Q96RR4
FRDPFECNMCGYRSH

IKZF3

476

Q9UKT9
GNYRCTCFDGFMLAH

SCUBE1

96

Q8IWY4
MGSYECHCREGFFLS

SCUBE3

131

Q8IX30
DCTHGQEMFYCFPDN

SLC38A11

366

Q08AI6
EDCGPSMYCQFASFQ

DKK3

151

Q9UBP4
DCHQFYLDYDLNGPM

DNAH5

1341

Q8TE73
IEMPYAYQCCAFGVC

LGR5

471

O75473
NGDVFETFMFPCQHC

PRDM2

351

Q13029
CFCADNVIPHFFCDM

OR1E2

176

P47887
LSFCTNMEIPHFFCD

OR7C2

166

O60412
ASCYDHPCFLRGMGD

OAS3

321

Q9Y6K5
INCHYFFEMLGQACL

RP1

2091

P56715
LYCPCMGRFGNQADH

POFUT1

36

Q9H488
YCGSNMVHQFFCDIP

OR14A16

166

Q8NHC5
FCGPNVIDHFFCDMY

OR4A4P

166

Q8NGN8
SYECCMAQLFGAHFL

OR4C3

91

Q8NH37
MFHYFCEDDGKFLCF

TRIM31

101

Q9BZY9
HEACLFAYCAGAMAG

SSPOP

416

A2VEC9
RKYCEHDFQMLFAPC

LIMS1

56

P48059
PCFFCDVCFRMLHYD

SNAPC3

376

Q92966
FCGNFEINHFYCADP

OR5M9

166

Q8NGP3
LHYCGMPQINHYFCD

OR6Y1

171

Q8NGX8
MACSPCEGLYFFEFV

CMTM4

76

Q8IZR5
DGLLEMFHCPYEGCS

ZNF653

461

Q96CK0
MFHCPYEGCSQVYVA

ZNF653

466

Q96CK0
TKGENCIYMHNEFPC

ZC3H6

316

P61129
FLSLFEHYNMCQVGC

MINDY4

646

Q4G0A6
AAKDSNAFFCPHCYM

ZNF521

506

Q96K83
NAFFCPHCYMGFLTD

ZNF521

511

Q96K83
RMHTCFDVYRCGFNP

EXT2

86

Q93063
FCNPVDSQHYMALLC

XYLB

321

O75191
TFVQHYECDDCGMAF

ZNF840P

146

A6NDX5
EAAHFCYLMAHVPFG

SEC16B

561

Q96JE7
GFCARAENCPYMHGD

ZC3H4

431

Q9UPT8
AENCPYMHGDFPCKL

ZC3H4

436

Q9UPT8
YECKQCAEAFYLMPH

ZIM2

356

Q9NZV7
AYQGCHFIGMPECEV

WRNIP1

561

Q96S55
FHGVCMFCNEEFLGN

ZNF277

171

Q9NRM2
PPVENEMFFCQHCDY

ZNF462

1186

Q96JM2
PYLCNDCGMTFSHFT

ZNF483

606

Q8TF39
NISAFHCNYCPEMFA

ZNF423

476

Q2M1K9
HCNYCPEMFADINSL

ZNF423

481

Q2M1K9
CGAVDMNEFYHCFLP

LCMT2

266

O60294
LSCPNHDGNVMEFYC

TRIM2

116

Q9C040
GMAFCALVHNFFPEA

SMTN

831

P53814
PNHEGKTMEFYCEAC

TRIM3

116

O75382