Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	carbohydrate binding	KLRK1 MGAM PLA2R1 CLEC9A MANBA CLEC4A NCAN PFKL CD209 FREM1	1.49e-06	310	91	10	GO:0030246
GeneOntologyMolecularFunction	acetyl-CoA carboxylase activity	ACACA ACACB	2.05e-05	2	91	2	GO:0003989
GeneOntologyMolecularFunction	serine-type peptidase activity	TPSD1 RELN CD5L TMPRSS11E TMPRSS7 PCSK4 ST14	4.50e-05	207	91	7	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	TPSD1 RELN CD5L TMPRSS11E TMPRSS7 PCSK4 ST14	5.24e-05	212	91	7	GO:0017171
GeneOntologyMolecularFunction	serine-type endopeptidase activity	TPSD1 CD5L TMPRSS11E TMPRSS7 PCSK4 ST14	2.34e-04	190	91	6	GO:0004252
GeneOntologyMolecularFunction	D-mannose binding	MANBA CLEC4A CD209	2.47e-04	27	91	3	GO:0005537
GeneOntologyMolecularFunction	BH3 domain binding	BCL2 BCL2L1	3.04e-04	6	91	2	GO:0051434
GeneOntologyMolecularFunction	CoA carboxylase activity	ACACA ACACB	3.04e-04	6	91	2	GO:0016421
GeneOntologyMolecularFunction	biotin binding	ACACA ACACB	3.04e-04	6	91	2	GO:0009374
GeneOntologyMolecularFunction	ligase activity, forming carbon-carbon bonds	ACACA ACACB	4.25e-04	7	91	2	GO:0016885
GeneOntologyMolecularFunction	monosaccharide binding	MANBA CLEC4A PFKL CD209	9.37e-04	95	91	4	GO:0048029
GeneOntologyMolecularFunction	death domain binding	BCL2 BCL2L1	1.10e-03	11	91	2	GO:0070513
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	MGAM MANBA GLB1L2 LCT	1.27e-03	103	91	4	GO:0004553
GeneOntologyMolecularFunction	BH domain binding	BCL2 BCL2L1	1.80e-03	14	91	2	GO:0051400
GeneOntologyMolecularFunction	glucosidase activity	MGAM LCT	2.08e-03	15	91	2	GO:0015926
GeneOntologyBiologicalProcess	malonyl-CoA biosynthetic process	ACACA ACACB	2.01e-05	2	93	2	GO:2001295
Domain	Lectin_C	KLRK1 PLA2R1 THBD CLEC9A CLEC4A NCAN CD209 FREM1	8.16e-09	84	92	8	PF00059
Domain	CLECT	KLRK1 PLA2R1 THBD CLEC9A CLEC4A NCAN CD209 FREM1	8.16e-09	84	92	8	SM00034
Domain	C_TYPE_LECTIN_2	KLRK1 PLA2R1 THBD CLEC9A CLEC4A NCAN CD209 FREM1	8.97e-09	85	92	8	PS50041
Domain	C-type_lectin-like	KLRK1 PLA2R1 THBD CLEC9A CLEC4A NCAN CD209 FREM1	9.85e-09	86	92	8	IPR001304
Domain	C-type_lectin-like/link	KLRK1 PLA2R1 THBD CLEC9A CLEC4A NCAN CD209 FREM1	3.02e-08	99	92	8	IPR016186
Domain	CTDL_fold	KLRK1 PLA2R1 THBD CLEC9A CLEC4A NCAN CD209 FREM1	5.56e-08	107	92	8	IPR016187
Domain	C_TYPE_LECTIN_1	KLRK1 PLA2R1 CLEC9A CLEC4A NCAN CD209 FREM1	1.32e-07	80	92	7	PS00615
Domain	-	PLA2R1 THBD CLEC9A CLEC4A NCAN CD209 FREM1	5.00e-07	97	92	7	3.10.100.10
Domain	C-type_lectin_CS	PLA2R1 CLEC9A CLEC4A NCAN CD209	2.16e-06	43	92	5	IPR018378
Domain	Bcl2/BclX	BCL2 BCL2L1	2.40e-05	2	92	2	IPR004725
Domain	ACC_central	ACACA ACACB	2.40e-05	2	92	2	PF08326
Domain	AcCoA_COase_cen	ACACA ACACB	2.40e-05	2	92	2	IPR013537
Domain	BH4	BCL2 BCL2L1	7.18e-05	3	92	2	PF02180
Domain	Bcl2_BH4_motif_CS	BCL2 BCL2L1	7.18e-05	3	92	2	IPR020731
Domain	BH4	BCL2 BCL2L1	7.18e-05	3	92	2	SM00265
Domain	Glycoside_hydrolase_SF	MGAM MANBA GLB1L2 LCT	1.34e-04	53	92	4	IPR017853
Domain	Carboxyl_trans	ACACA ACACB	1.43e-04	4	92	2	PF01039
Domain	COA_CT_CTER	ACACA ACACB	1.43e-04	4	92	2	PS50989
Domain	COA_CT_NTER	ACACA ACACB	1.43e-04	4	92	2	PS50980
Domain	COA_CT_N	ACACA ACACB	1.43e-04	4	92	2	IPR011762
Domain	COA_CT_C	ACACA ACACB	1.43e-04	4	92	2	IPR011763
Domain	Carboxyl_trans	ACACA ACACB	1.43e-04	4	92	2	IPR000022
Domain	SEA	TMPRSS11E TMPRSS7 ST14	1.66e-04	22	92	3	PF01390
Domain	SEA	TMPRSS11E TMPRSS7 ST14	1.91e-04	23	92	3	PS50024
Domain	SEA_dom	TMPRSS11E TMPRSS7 ST14	1.91e-04	23	92	3	IPR000082
Domain	Biotin_BS	ACACA ACACB	2.38e-04	5	92	2	IPR001882
Domain	Biotin_COase_C	ACACA ACACB	2.38e-04	5	92	2	IPR005482
Domain	BC	ACACA ACACB	2.38e-04	5	92	2	PS50979
Domain	Biotin_carb_C	ACACA ACACB	2.38e-04	5	92	2	SM00878
Domain	Biotin_carb_C	ACACA ACACB	2.38e-04	5	92	2	PF02785
Domain	Biotin_carboxylation_dom	ACACA ACACB	2.38e-04	5	92	2	IPR011764
Domain	CPSASE_1	ACACA ACACB	2.38e-04	5	92	2	PS00866
Domain	Bcl2_BH4	BCL2 BCL2L1	2.38e-04	5	92	2	IPR003093
Domain	BH4_2	BCL2 BCL2L1	2.38e-04	5	92	2	PS50063
Domain	BIOTIN	ACACA ACACB	2.38e-04	5	92	2	PS00188
Domain	BH4_1	BCL2 BCL2L1	2.38e-04	5	92	2	PS01260
Domain	TSP_1	THBS2 ADAMTS6 PAPLN SEMA5A	2.63e-04	63	92	4	PF00090
Domain	TSP1	THBS2 ADAMTS6 PAPLN SEMA5A	2.97e-04	65	92	4	SM00209
Domain	TSP1_rpt	THBS2 ADAMTS6 PAPLN SEMA5A	2.97e-04	65	92	4	IPR000884
Domain	TSP1	THBS2 ADAMTS6 PAPLN SEMA5A	2.97e-04	65	92	4	PS50092
Domain	Rudment_hybrid_motif	ACACA ACACB	3.55e-04	6	92	2	IPR011054
Domain	CPSASE_2	ACACA ACACB	3.55e-04	6	92	2	PS00867
Domain	-	MANBA GLB1L2 HECTD1 PCSK4	4.63e-04	73	92	4	2.60.120.260
Domain	CbamoylP_synth_lsu-like_ATP-bd	ACACA ACACB	4.96e-04	7	92	2	IPR005479
Domain	BC-like_N	ACACA ACACB	4.96e-04	7	92	2	IPR005481
Domain	CPSase_L_D2	ACACA ACACB	4.96e-04	7	92	2	PF02786
Domain	Biotin_carb_N	ACACA ACACB	4.96e-04	7	92	2	PF00289
Domain	P_TREFOIL_1	ZP1 MGAM	6.59e-04	8	92	2	PS00025
Domain	Bcl2_BH2_motif_CS	BCL2 BCL2L1	6.59e-04	8	92	2	IPR020726
Domain	Bcl2_BH3_motif_CS	BCL2 BCL2L1	6.59e-04	8	92	2	IPR020728
Domain	Bcl2_BH1_motif_CS	BCL2 BCL2L1	6.59e-04	8	92	2	IPR020717
Domain	P_trefoil_CS	ZP1 MGAM	6.59e-04	8	92	2	IPR017957
Domain	-	MANBA GLB1L2 LCT	6.75e-04	35	92	3	3.20.20.80
Domain	P_TREFOIL_2	ZP1 MGAM	8.45e-04	9	92	2	PS51448
Domain	Biotin_lipoyl	ACACA ACACB	8.45e-04	9	92	2	PF00364
Domain	PD	ZP1 MGAM	8.45e-04	9	92	2	SM00018
Domain	Glyco_hydro_catalytic_dom	MANBA GLB1L2 LCT	8.61e-04	38	92	3	IPR013781
Domain	TRYPSIN_SER	TPSD1 TMPRSS11E TMPRSS7 ST14	1.02e-03	90	92	4	IPR033116
Domain	BIOTINYL_LIPOYL	ACACA ACACB	1.05e-03	10	92	2	PS50968
Domain	Biotin_lipoyl	ACACA ACACB	1.05e-03	10	92	2	IPR000089
Domain	Galactose-bd-like	MANBA GLB1L2 HECTD1 PCSK4	1.20e-03	94	92	4	IPR008979
Domain	-	ZP1 MGAM	1.28e-03	11	92	2	4.10.110.10
Domain	BH1	BCL2 BCL2L1	1.28e-03	11	92	2	PS01080
Domain	Blc2_fam	BCL2 BCL2L1	1.28e-03	11	92	2	IPR026298
Domain	Bcl-2	BCL2 BCL2L1	1.53e-03	12	92	2	PF00452
Domain	P_trefoil_dom	ZP1 MGAM	1.53e-03	12	92	2	IPR000519
Domain	Single_hybrid_motif	ACACA ACACB	1.53e-03	12	92	2	IPR011053
Domain	TRYPSIN_HIS	TPSD1 TMPRSS11E TMPRSS7 ST14	1.68e-03	103	92	4	IPR018114
Domain	-	ACACA ACACB	1.81e-03	13	92	2	3.40.50.20
Domain	BCL2_FAMILY	BCL2 BCL2L1	1.81e-03	13	92	2	PS50062
Domain	Bcl2-like	BCL2 BCL2L1	1.81e-03	13	92	2	IPR002475
Domain	BH2	BCL2 BCL2L1	1.81e-03	13	92	2	PS01258
Domain	TRYPSIN_SER	TPSD1 TMPRSS11E TMPRSS7 ST14	1.87e-03	106	92	4	PS00135
Domain	TRYPSIN_HIS	TPSD1 TMPRSS11E TMPRSS7 ST14	1.93e-03	107	92	4	PS00134
Domain	ATP_GRASP	ACACA ACACB	2.10e-03	14	92	2	PS50975
Domain	PLAC	ADAMTS6 PAPLN	2.10e-03	14	92	2	PF08686
Domain	ATP-grasp	ACACA ACACB	2.10e-03	14	92	2	IPR011761
Domain	PreATP-grasp_dom	ACACA ACACB	2.10e-03	14	92	2	IPR016185
Domain	Peptidase_S1A	TPSD1 TMPRSS11E TMPRSS7 ST14	2.36e-03	113	92	4	IPR001314
Domain	-	TMPRSS11E TMPRSS7	2.42e-03	15	92	2	3.30.70.960
Domain	-	ACACA ACACB	2.42e-03	15	92	2	3.30.1490.20
Domain	TRYPSIN_DOM	TPSD1 TMPRSS11E TMPRSS7 ST14	2.51e-03	115	92	4	PS50240
Domain	Tryp_SPc	TPSD1 TMPRSS11E TMPRSS7 ST14	2.67e-03	117	92	4	SM00020
Domain	Post-SET_dom	EHMT2 KMT2A	2.75e-03	16	92	2	IPR003616
Domain	PostSET	EHMT2 KMT2A	2.75e-03	16	92	2	SM00508
Domain	Guanylate_kinase_CS	DLG3 PALS2	2.75e-03	16	92	2	IPR020590
Domain	POST_SET	EHMT2 KMT2A	2.75e-03	16	92	2	PS50868
Domain	Trypsin_dom	TPSD1 TMPRSS11E TMPRSS7 ST14	3.02e-03	121	92	4	IPR001254
Domain	Trypsin	TPSD1 TMPRSS11E TMPRSS7 ST14	3.02e-03	121	92	4	PF00089
Domain	BH3	BCL2 BCL2L1	3.11e-03	17	92	2	PS01259
Domain	Peptidase_S1_PA	TPSD1 TMPRSS11E TMPRSS7 ST14	3.20e-03	123	92	4	IPR009003
Domain	ATP_grasp_subdomain_1	ACACA ACACB	3.49e-03	18	92	2	IPR013815
Domain	-	ACACA ACACB	3.49e-03	18	92	2	3.30.470.20
Domain	PLAC	ADAMTS6 PAPLN	3.89e-03	19	92	2	PS50900
Domain	PLAC	ADAMTS6 PAPLN	3.89e-03	19	92	2	IPR010909
Domain	-	ACACA ACACB	4.74e-03	21	92	2	3.90.226.10
Domain	ClpP/crotonase-like_dom	ACACA ACACB	4.74e-03	21	92	2	IPR029045
Pubmed	Binding of HIV-1 gp120 to DC-SIGN promotes ASK-1-dependent activation-induced apoptosis of human dendritic cells.	BCL2 BCL2L1 CD209	1.84e-07	5	93	3	23382671
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	THBD RELN THBS2 NCAN PAPLN SEMA5A PTH1R	1.62e-06	210	93	7	16537572
Pubmed	Dendritic cell immunoreceptor regulates Chikungunya virus pathogenesis in mice.	CLEC4A CD209	7.07e-06	2	93	2	23487448
Pubmed	HIV-specific CD8+ T cells exhibit markedly reduced levels of Bcl-2 and Bcl-xL.	BCL2 BCL2L1	7.07e-06	2	93	2	15034060
Pubmed	bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria.	BCL2 BCL2L1	7.07e-06	2	93	2	7607090
Pubmed	A novel inhibitory mechanism of mitochondrion-dependent apoptosis by a herpesviral protein.	BCL2 BCL2L1	7.07e-06	2	93	2	18069888
Pubmed	siRNA-mediated Bcl-2 and Bcl-xl gene silencing sensitizes human hepatoblastoma cells to chemotherapeutic drugs.	BCL2 BCL2L1	7.07e-06	2	93	2	17439414
Pubmed	Inhibition of apoptosis in human breast cancer cells: role in tumor progression to the metastatic state.	BCL2 BCL2L1	7.07e-06	2	93	2	12209955
Pubmed	Glucose metabolism is required for oxidized LDL-induced macrophage survival: role of PI3K and Bcl-2 family proteins.	BCL2 BCL2L1	7.07e-06	2	93	2	19667115
Pubmed	DC-SIGN plays a stronger role than DCIR in mediating HIV-1 capture and transfer.	CLEC4A CD209	7.07e-06	2	93	2	24928041
Pubmed	Development of a human neuronal cell model for human immunodeficiency virus (HIV)-infected macrophage-induced neurotoxicity: apoptosis induced by HIV type 1 primary isolates and evidence for involvement of the Bcl-2/Bcl-xL-sensitive intrinsic apoptosis pathway.	BCL2 BCL2L1	7.07e-06	2	93	2	12186923
Pubmed	Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.	ACACA ACACB	7.07e-06	2	93	2	24944901
Pubmed	The Ewing Family of Tumors Relies on BCL-2 and BCL-XL to Escape PARP Inhibitor Toxicity.	BCL2 BCL2L1	7.07e-06	2	93	2	30348635
Pubmed	Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription.	ACACA ACACB	7.07e-06	2	93	2	20139635
Pubmed	Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells.	ACACA ACACB	7.07e-06	2	93	2	28081256
Pubmed	Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.	ACACA ACACB	7.07e-06	2	93	2	26976583
Pubmed	Variable BCL2/BCL2L1 ratio in multiple myeloma with t(11;14).	BCL2 BCL2L1	7.07e-06	2	93	2	30429160
Pubmed	(-)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X(L)-mediated apoptosis resistance.	BCL2 BCL2L1	7.07e-06	2	93	2	15657350
Pubmed	Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells.	THBD CLEC9A	7.07e-06	2	93	2	20479117
Pubmed	Distinct roles of Bcl-2 and Bcl-Xl in the apoptosis of human bone marrow mesenchymal stem cells during differentiation.	BCL2 BCL2L1	7.07e-06	2	93	2	21589877
Pubmed	AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation.	ACACA ACACB	7.07e-06	2	93	2	25001074
Pubmed	bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death.	BCL2 BCL2L1	7.07e-06	2	93	2	7753802
Pubmed	The subcellular localization of acetyl-CoA carboxylase 2.	ACACA ACACB	7.07e-06	2	93	2	10677481
Pubmed	Susceptibility of podocytes to palmitic acid is regulated by fatty acid oxidation and inversely depends on acetyl-CoA carboxylases 1 and 2.	ACACA ACACB	7.07e-06	2	93	2	24338821
Pubmed	De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.	ACACA ACACB	7.07e-06	2	93	2	25282359
Pubmed	Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab.	ACACA ACACB	7.07e-06	2	93	2	27693630
Pubmed	Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membrane.	BCL2 BCL2L1	7.07e-06	2	93	2	12515824
Pubmed	Transglutaminase 3 Promotes Skin Inflammation in Atopic Dermatitis by Activating Monocyte-Derived Dendritic Cells via DC-SIGN.	TGM3 CD209	7.07e-06	2	93	2	31425706
Pubmed	Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.	ACACA ACACB	7.07e-06	2	93	2	32215608
Pubmed	Induction of apoptosis and antitumor effects of a small molecule inhibitor of Bcl-2 and Bcl-xl, gossypol acetate, in multiple myeloma in vitro and in vivo.	BCL2 BCL2L1	7.07e-06	2	93	2	23708869
Pubmed	Activity and structure of human acetyl-CoA carboxylase targeted by a specific inhibitor.	ACACA ACACB	7.07e-06	2	93	2	29772612
Pubmed	Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin.	ACACA ACACB	7.07e-06	2	93	2	29976587
Pubmed	Autophagy is activated, but is not required for the G0 function of BCL-2 or BCL-xL.	BCL2 BCL2L1	7.07e-06	2	93	2	18758240
Pubmed	Suppression of endoplasmic reticulum stress-induced caspase activation and cell death by the overexpression of Bcl-xL or Bcl-2.	BCL2 BCL2L1	7.07e-06	2	93	2	17301078
Pubmed	Cleavage of anti-apoptotic Bcl-2 family members after TCR stimulation contributes to the decision between T cell activation and apoptosis.	BCL2 BCL2L1	7.07e-06	2	93	2	23203923
Pubmed	Structure and regulation of acetyl-CoA carboxylase genes of metazoa.	ACACA ACACB	7.07e-06	2	93	2	15749055
Pubmed	Regulation of mammalian target of rapamycin complex 1 by Bcl-2 and Bcl-XL proteins.	BCL2 BCL2L1	7.07e-06	2	93	2	23960074
Pubmed	BCL(X)L and BCL2 increase mitochondrial dynamics in breast cancer cell: Evidence from functional and genetic studies.	BCL2 BCL2L1	7.07e-06	2	93	2	34214511
Pubmed	Mitochondrially targeted Bcl-2 and Bcl-X(L) chimeras elicit different apoptotic responses.	BCL2 BCL2L1	7.07e-06	2	93	2	18182854
Pubmed	BDCA3(+)CLEC9A(+) human dendritic cell function and development.	THBD CLEC9A	7.07e-06	2	93	2	24910448
Pubmed	The spliced variant of hepatitis B virus protein, HBSP, interacts with Bcl-2/Bcl-xl in vitro and induces apoptosis in HepG2 cells.	BCL2 BCL2L1	7.07e-06	2	93	2	18543286
Pubmed	AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis.	ACACA ACACB	7.07e-06	2	93	2	29433631
Pubmed	Expression of Bcl-2 and Bcl-xL in cutaneous and bone marrow lesions of mastocytosis.	BCL2 BCL2L1	7.07e-06	2	93	2	12937123
Pubmed	BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases.	BCL2 BCL2L1	7.07e-06	2	93	2	12420213
Pubmed	Regulation of the lifespan in dendritic cell subsets.	BCL2 BCL2L1	7.07e-06	2	93	2	17267035
Pubmed	APG-1252-12A induces mitochondria-dependent apoptosis through inhibiting the antiapoptotic proteins Bcl-2/Bcl-xl in HL-60 cells.	BCL2 BCL2L1	7.07e-06	2	93	2	28586007
Pubmed	BCL-2 and BCL-XL restrict lineage choice during hematopoietic differentiation.	BCL2 BCL2L1	7.07e-06	2	93	2	12721288
Pubmed	Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction.	BCL2 BCL2L1	7.07e-06	2	93	2	23091012
Pubmed	Antiapoptotic proteins Bcl-2 and Bcl-XL inhibit Clostridium difficile toxin A-induced cell death in human epithelial cells.	BCL2 BCL2L1	7.07e-06	2	93	2	19797069
Pubmed	BCL2 and BCLxL are key determinants of resistance to antitubulin chemotherapeutics in melanoma cells.	BCL2 BCL2L1	7.07e-06	2	93	2	23802633
Pubmed	Bcl-XL and Bcl-2 expression in bilharzial squamous cell carcinoma of the urinary bladder: which protein is prognostic?	BCL2 BCL2L1	7.07e-06	2	93	2	18342927
Pubmed	Blocking AMPK signalling to acetyl-CoA carboxylase increases cisplatin-induced acute kidney injury and suppresses the benefit of metformin.	ACACA ACACB	7.07e-06	2	93	2	36076520
Pubmed	Evaluation of cytotoxic effects induced by bcl-2 and bcl-xL antisense-oligodeoxynucleotides in normal urothelium and transitional cell carcinoma.	BCL2 BCL2L1	7.07e-06	2	93	2	19020723
Pubmed	Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.	ACACA ACACB	7.07e-06	2	93	2	28290443
Pubmed	Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.	ACACA ACACB	7.07e-06	2	93	2	30244972
Pubmed	AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue.	ACACA ACACB	2.12e-05	3	93	2	34668531
Pubmed	Resistance to chemotherapy-induced apoptosis via decreased caspase-3 activity and overexpression of antiapoptotic proteins in ovarian cancer.	BCL2 BCL2L1	2.12e-05	3	93	2	15156398
Pubmed	Evasion of cell death: A contributory factor in prostate cancer development and treatment resistance.	BCL2 BCL2L1	2.12e-05	3	93	2	34343635
Pubmed	Mechanism of Bcl-2 and Bcl-X(L) inhibition of NLRP1 inflammasome: loop domain-dependent suppression of ATP binding and oligomerization.	BCL2 BCL2L1	2.12e-05	3	93	2	19223583
Pubmed	Regulation of Bax mitochondrial localization by Bcl-2 and Bcl-x(L): keep your friends close but your enemies closer.	BCL2 BCL2L1	2.12e-05	3	93	2	23064052
Pubmed	AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation.	ACACA ACACB	2.12e-05	3	93	2	30018077
Pubmed	Regulation of bcl-2, bcl-XL and bax in the control of apoptosis by hematopoietic cytokines and dexamethasone.	BCL2 BCL2L1	2.12e-05	3	93	2	7669718
Pubmed	Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma Models.	BCL2 BCL2L1	2.12e-05	3	93	2	26939706
Pubmed	Association of Oligoadenylate Synthetase Gene Cluster and DC-SIGN (CD209) Gene Polymorphisms with Clinical Symptoms in Chikungunya Virus Infection.	OAS3 CD209	2.12e-05	3	93	2	26398832
Pubmed	Acetyl-coenzyme A carboxylase alpha gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels.	ACACA ACACB	2.12e-05	3	93	2	19846279
Pubmed	Exploring genetic variations that may be associated with the direct effects of some antipsychotics on lipid levels.	ACACA ACACB	2.12e-05	3	93	2	18031993
Pubmed	AdHu5-apoptin induces G2/M arrest and apoptosis in p53-mutated human gastric cancer SGC-7901 cells.	BCL2 BCL2L1	2.12e-05	3	93	2	23812727
Pubmed	Apoptosis and expression of Bcl-2, Bcl-XL, and Bax in renal cell carcinomas.	BCL2 BCL2L1	2.12e-05	3	93	2	12025227
Pubmed	Lewis y enhances CAM-DR in ovarian cancer cells by activating the FAK signaling pathway and upregulating Bcl-2/Bcl-XL expression.	BCL2 BCL2L1	2.12e-05	3	93	2	25726913
Pubmed	Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2.	BCL2 BCL2L1	2.12e-05	3	93	2	30860026
Pubmed	Effect of bax, bcl-2 and bcl-xL on regulating apoptosis in tissues of normal liver and hepatocellular carcinoma.	BCL2 BCL2L1	2.12e-05	3	93	2	12439925
Pubmed	Role of phospholipase D2 in anti-apoptotic signaling through increased expressions of Bcl-2 and Bcl-xL.	BCL2 BCL2L1	2.12e-05	3	93	2	17541981
Pubmed	Praf2 is a novel Bcl-xL/Bcl-2 interacting protein with the ability to modulate survival of cancer cells.	BCL2 BCL2L1	2.12e-05	3	93	2	21203533
Pubmed	p53 has a direct apoptogenic role at the mitochondria.	BCL2 BCL2L1	2.12e-05	3	93	2	12667443
Pubmed	Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis.	ACACA ACACB	2.12e-05	3	93	2	20457939
Pubmed	Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma.	BCL2 BCL2L1	2.12e-05	3	93	2	17384650
Pubmed	Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism.	ACACA ACACB	2.12e-05	3	93	2	36417534
Pubmed	Different expression patterns of Bcl-2, Bcl-xl, and Bax proteins after sublethal forebrain ischemia in C57Black/Crj6 mouse striatum.	BCL2 BCL2L1	2.12e-05	3	93	2	12791942
Pubmed	PUMA induces the rapid apoptosis of colorectal cancer cells.	BCL2 BCL2L1	2.12e-05	3	93	2	11463391
Pubmed	PUMA, a novel proapoptotic gene, is induced by p53.	BCL2 BCL2L1	2.12e-05	3	93	2	11463392
Pubmed	Increased tubulointerstitial recruitment of human CD141(hi) CLEC9A(+) and CD1c(+) myeloid dendritic cell subsets in renal fibrosis and chronic kidney disease.	THBD CLEC9A	2.12e-05	3	93	2	24049150
Pubmed	Mapping the BH3 Binding Interface of Bcl-xL, Bcl-2, and Mcl-1 Using Split-Luciferase Reassembly.	BCL2 BCL2L1	2.12e-05	3	93	2	25844633
Pubmed	Precursor IGF-II (proIGF-II) and mature IGF-II (mIGF-II) induce Bcl-2 And Bcl-X L expression through different signaling pathways in breast cancer cells.	BCL2 BCL2L1	2.12e-05	3	93	2	18428028
Pubmed	Bcl-G, a novel pro-apoptotic member of the Bcl-2 family.	BCL2 BCL2L1	2.12e-05	3	93	2	11054413
Pubmed	Molecular interactions of Bcl-2 and Bcl-xL with mortalin: identification and functional characterization.	BCL2 BCL2L1	2.12e-05	3	93	2	24050266
Pubmed	Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate.	ACACA ACACB	2.12e-05	3	93	2	18455495
Pubmed	High-resolution analysis of the conformational transition of pro-apoptotic Bak at the lipid membrane.	BCL2 BCL2L1	2.12e-05	3	93	2	34523144
Pubmed	A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum.	BCL2 BCL2L1	2.12e-05	3	93	2	20577262
Pubmed	Transmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xL.	BCL2 BCL2L1	2.12e-05	3	93	2	29507230
Pubmed	Paradoxical inhibition of c-myc-induced carcinogenesis by Bcl-2 in transgenic mice.	BCL2 BCL2L1	2.12e-05	3	93	2	10519417
Pubmed	Granulocyte macrophage-colony stimulating factor shows anti-apoptotic activity in neural progenitor cells via JAK/STAT5-Bcl-2 pathway.	BCL2 BCL2L1	2.12e-05	3	93	2	21052840
Pubmed	Tumor necrosis factor attenuates prion protein-deficient neuronal cell death by increases in anti-apoptotic Bcl-2 family proteins.	BCL2 BCL2L1	2.12e-05	3	93	2	14550262
Pubmed	Localization of bcl-2, bax, and bcl-x mRNAs in the developing inner ear of the mouse.	BCL2 BCL2L1	2.12e-05	3	93	2	8836552
Pubmed	Overexpression of Bcl-2 or Bcl-XL transgenes and photoreceptor degeneration.	BCL2 BCL2L1	2.12e-05	3	93	2	8933760
Pubmed	The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis.	BCL2 BCL2L1	2.12e-05	3	93	2	14739602
Pubmed	BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity.	BCL2 BCL2L1	2.12e-05	3	93	2	9305851
Pubmed	Novel BNIP1 variants and their interaction with BCL2 family members.	BCL2 BCL2L1	2.12e-05	3	93	2	10217402
Pubmed	Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells.	BCL2 BCL2L1	2.12e-05	3	93	2	12070027
Pubmed	Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells.	BCL2 BCL2L1	2.12e-05	3	93	2	20090905
Pubmed	Simultaneous siRNA-mediated knockdown of antiapoptotic BCL2, Bcl-xL, XIAP and survivin in bladder cancer cells.	BCL2 BCL2L1	2.12e-05	3	93	2	22797576
Interaction	ZNF223 interactions	EHMT2 ZNF223 HECTD1 ZNF284	9.33e-06	30	90	4	int:ZNF223
Interaction	B4GALT2 interactions	TUBGCP6 MISP EP400 ASCC3 PPP1R13L ST14	1.55e-05	119	90	6	int:B4GALT2
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	KLRK1 THBD NCAN FREM1	1.39e-05	41	65	4	1298
GeneFamily	C-type lectin domain family	PLA2R1 CLEC9A CLEC4A CD209	2.42e-05	47	65	4	494
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	KLRK1 LIFR THBD CD1E CLEC9A CLEC4A CD209	5.19e-04	394	65	7	471
GeneFamily	BCL2 family	BCL2 BCL2L1	1.13e-03	14	65	2	1057
GeneFamily	Proteases, serine	TMPRSS11E TMPRSS7 ST14	1.51e-03	63	65	3	738
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	DLG3 PALS2	3.91e-03	26	65	2	904
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	DLG3 BCL2 BCL2L1 PREX2	4.09e-03	181	65	4	694
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	EHMT2 KMT2A	6.63e-03	34	65	2	487
Coexpression	NABA_MATRISOME	ZP1 TGM3 CPAMD8 RELN THBS2 CLEC9A ANGPTL2 ADAMTS6 CLEC4A NCAN WNT9B PAPLN SEMA5A CRISPLD1 ST14 CD209 FREM1	1.09e-07	1026	93	17	M5889
Coexpression	NABA_MATRISOME	ZP1 TGM3 RELN THBS2 CLEC9A ANGPTL2 ADAMTS6 CLEC4A NCAN WNT9B PAPLN SEMA5A CRISPLD1 ST14 CD209 FREM1	4.80e-07	1008	93	16	MM17056
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	LIFR CPAMD8 ACACA UNC13C USP54 PALS2	2.52e-06	185	93	6	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	THBS2 ADAMTS6 SPSB1 PAPLN BCL2 L3MBTL4	2.77e-06	188	93	6	74f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ADAMTS6 SPSB1 PAPLN SEMA5A BCL2 L3MBTL4	2.86e-06	189	93	6	b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCell	BLOOD--(3)_DC_(cDC+pDC)\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	THBD CD1E CLEC9A CLEC4A KCNK17 ST14	3.13e-06	192	93	6	e290c55a1321e9e577f49e8ba20501b2c8150044
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LIFR DMKN SEMA5A UNC13C PREX2 FREM1	3.32e-06	194	93	6	5f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LIFR THBD ADAMTS6 DTL PREX2 L3MBTL4	3.32e-06	194	93	6	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	SEMA5A PALS2 KCNK17 ADGRA2 PTH1R PREX2	3.96e-06	200	93	6	0c648941447c738caf62f2d71e296d6cca492c8b
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA5A PALS2 KCNK17 ADGRA2 PTH1R PREX2	3.96e-06	200	93	6	522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCell	Bronchial-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LIFR CPAMD8 RELN SPSB1 PALS2 CRISPLD1	3.96e-06	200	93	6	b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SEMA5A PALS2 KCNK17 ADGRA2 PTH1R PREX2	3.96e-06	200	93	6	94f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCell	Bronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LIFR CPAMD8 RELN SPSB1 PALS2 CRISPLD1	3.96e-06	200	93	6	7c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 ADAMTS6 ZNF223 TMPRSS7 PREX2	1.58e-05	150	93	5	322aa0c3fc159a4b2897daac881dfc744b24ffc4
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-LMPP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CLEC9A EP400 TECPR2 SCNN1D PPP1R13L	2.16e-05	160	93	5	60fa1c717410aad7e8647703cb416cd7617cac29
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_dendritic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CLEC9A KCNK17 CRISPLD1 PTH1R FREM1	2.29e-05	162	93	5	233011408f022647932c81ebab78f9813e3c6833
ToppCell	facs-Marrow-KLS-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLRK1 ZP1 CLEC9A ADGRA2 L3MBTL4	2.80e-05	169	93	5	d6ad3b637de2935c656aad47ad82d6e8a8bd1227
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN ADAMTS6 WNT9B PAPLN SEMA5A	2.80e-05	169	93	5	eb3b8e473192c4b8688f2f8da400116dd6fe193d
ToppCell	facs-Marrow-KLS-24m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLRK1 ZP1 CLEC9A ADGRA2 L3MBTL4	2.80e-05	169	93	5	60ef186518d0dc63dbded2a77c65cfe3129df754
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LIFR THBD DTL PAPLN SEMA5A	2.80e-05	169	93	5	559e98216720e4babf0b0941100f1b485c35b11b
ToppCell	NS-critical-d_0-4-Epithelial-FOXN4+\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PLA2R1 SEMA5A GLB1L2 STAM PCSK4	3.05e-05	172	93	5	a00bb44d33658cb3a98accd6b60f3ce964c425b4
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors\|lymph-node_spleen / Manually curated celltypes from each tissue	CLEC9A KCNK17 CRISPLD1 PTH1R FREM1	3.22e-05	174	93	5	6d9bdf4d28ff8ebb66ffd1ccdd6a4fe9440a83f3
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB\|TCGA-Thymus / Sample_Type by Project: Shred V9	PLA2R1 CPAMD8 HCAR1 CRISPLD1 PTH1R	3.31e-05	175	93	5	50f9b994bdd389158f92f891944ea81b2fb15eef
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122\|Adult / Lineage, Cell type, age group and donor	LIFR CPAMD8 UNC13C USP54 PALS2	3.40e-05	176	93	5	3fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell	ASK452-Endothelial-Lymphatic\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	THBD RELN DTL EI24 PGM2L1	3.40e-05	176	93	5	b4d280ecc07701d526f50d44c45ea91b3eeb00b1
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PLA2R1 ACACB CTC1 DMKN CRISPLD1	3.59e-05	178	93	5	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ANGPTL2 ADAMTS6 SPSB1 BCL2 PTH1R	4.10e-05	183	93	5	de08f9ea02b7244d5a8788064631d10f06565337
ToppCell	Pericytes-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	SEMA5A KCNK17 ADGRA2 RBM20 PTH1R	4.10e-05	183	93	5	4617b18da8d699a44e4c47980197b1e7eb951470
ToppCell	(7)_DC_plasmacytoid\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	THBD PAPLN KCNK17 TMEM132B ST14	4.10e-05	183	93	5	2c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CPAMD8 ACACA UNC13C USP54 PALS2	4.21e-05	184	93	5	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN THBS2 ANGPTL2 PAPLN PTH1R	4.32e-05	185	93	5	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN THBS2 ANGPTL2 PAPLN PTH1R	4.32e-05	185	93	5	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN THBS2 ANGPTL2 PAPLN PTH1R	4.32e-05	185	93	5	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	THBS2 SEMA5A BCL2 ADGRA2 PTH1R	4.43e-05	186	93	5	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPLN SEMA5A BCL2 PALS2 L3MBTL4	4.43e-05	186	93	5	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	3'_v3-blood-Myeloid_Dendritic-DC2\|blood / Manually curated celltypes from each tissue	CD1E CLEC4A KCNK17 HECTD1 PTH1R	4.54e-05	187	93	5	9f3db9f0e5de34aeabfe5984f675bc7a65435df7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPLN SEMA5A BCL2 PALS2 L3MBTL4	4.54e-05	187	93	5	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SP9 PALS2 PREX2 FREM1	4.66e-05	188	93	5	0501a8aa850bd2e347020abd1cac4d8075738189
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SP9 PALS2 PREX2 FREM1	4.66e-05	188	93	5	433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	THBD CLEC9A WNT9B PAPLN ADGRA2	4.66e-05	188	93	5	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-pDC\|lymph-node_spleen / Manually curated celltypes from each tissue	THBD SEMA5A KCNK17 TMEM132B ST14	4.78e-05	189	93	5	6c2ace61a7d62bcf7e76b73e2da8b722d03e713b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPLN SEMA5A BCL2 PALS2 L3MBTL4	4.78e-05	189	93	5	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	droplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2R1 THBS2 ANGPTL2 PTH1R FREM1	4.90e-05	190	93	5	8cb950effc449ae59a915132ecc079be54d1acfe
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPLN SEMA5A BCL2 PALS2 L3MBTL4	4.90e-05	190	93	5	989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCell	droplet-Pancreas-Exocrine-24m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2R1 THBS2 ANGPTL2 PTH1R FREM1	4.90e-05	190	93	5	5dfbd064ab1f8a0b18b5975c47f8e79697f3db15
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LIFR ADAMTS6 AAMDC ADGRA2 PREX2	4.90e-05	190	93	5	d0297d678498e346e56cf95fe9e3db7d3ad3b837
ToppCell	droplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2R1 THBS2 ANGPTL2 PTH1R FREM1	4.90e-05	190	93	5	17a73a658fb30a4322b31e38db7b240023738f29
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ADAMTS6 DTL SEMA5A BCL2 ZNF367	4.90e-05	190	93	5	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	THBD CD1E CLEC9A KCNK17 TMEM132B	5.02e-05	191	93	5	c3ff4342e0eea1e1f071b1fbca14a6dd4df0c696
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 SPSB1 SEMA5A PALS2 ADGRA2	5.02e-05	191	93	5	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN ADAMTS6 SEMA5A PREX2 L3MBTL4	5.02e-05	191	93	5	06760c3bb40e4f66879a5f5e09c9abfce4ebbba3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPLN SEMA5A BCL2 PALS2 L3MBTL4	5.02e-05	191	93	5	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	THBS2 SEMA5A BCL2 ADGRA2 PTH1R	5.02e-05	191	93	5	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LIFR THBD ADAMTS6 WNT9B PREX2	5.15e-05	192	93	5	52acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN ADAMTS6 SEMA5A PREX2 L3MBTL4	5.15e-05	192	93	5	6a252e298f8a454623fa9c1c893a7a45a886d694
ToppCell	Hippocampus-Endothelial\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PLA2R1 THBD ANGPTL2 HCAR1 ADGRA2	5.15e-05	192	93	5	36deadab892d3e639a71f33697bb2d3cbbaa5372
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Vein\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LIFR THBD ADAMTS6 WNT9B PREX2	5.15e-05	192	93	5	717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 ANGPTL2 DMKN CRISPLD1 FREM1	5.28e-05	193	93	5	7cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SP9 UNC13C PREX2 FREM1	5.28e-05	193	93	5	294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANGPTL2 ADGRA2 CRISPLD1 PTH1R FREM1	5.28e-05	193	93	5	59b8186d0221fba06a16157e9d148399ed801f38
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LIFR THBD ADAMTS6 DTL PREX2	5.28e-05	193	93	5	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANGPTL2 ADGRA2 CRISPLD1 PTH1R FREM1	5.28e-05	193	93	5	dc92680b4bb9fc26430c92e03adb839c8c3b3b98
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANGPTL2 ADGRA2 CRISPLD1 PTH1R FREM1	5.28e-05	193	93	5	03678162648bd5b1d65a5450b60c8863edbf95c7
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SP9 UNC13C PREX2 FREM1	5.28e-05	193	93	5	3d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SP9 UNC13C PREX2 FREM1	5.41e-05	194	93	5	52aebb0b563e2c2058e7f0554ae870e47692b163
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM CPAMD8 WNT9B UNC13C FREM1	5.41e-05	194	93	5	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM CPAMD8 WNT9B UNC13C FREM1	5.41e-05	194	93	5	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SP9 UNC13C PREX2 FREM1	5.41e-05	194	93	5	bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCell	10x5'-Liver-Myeloid_Dendritic\|Liver / Manually curated celltypes from each tissue	THBD CD1E CLEC9A KCNK17 ST14	5.41e-05	194	93	5	e6391bc7073831847c469ef0b0c437118e1f151f
ToppCell	21-Trachea-Immune-Hematopoietic,_Macrophage\|Trachea / Age, Tissue, Lineage and Cell class	CD1E CLEC9A CD5L CLEC4A CD209	5.41e-05	194	93	5	3c4ac5f91b10802990b84db3406f5e71f8ee8b74
ToppCell	COPD-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	CPAMD8 SPSB1 ZSWIM6 PALS2 ADGRA2	5.68e-05	196	93	5	af96fb94886e9395f3e2cd0a293af29229d017fe
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	LIFR THBS2 SEMA5A RBM20 PTH1R	5.82e-05	197	93	5	2ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_2\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	NCAN SP9 PGM2L1 ZSWIM6 CORO7	5.96e-05	198	93	5	b73b9feb82997b654718aa27f33ca7b454214802
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-SMG_Basal/Duct-SMG_Basal/Duct\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MISP DMKN PGM2L1 BCL2L1 ST14	5.96e-05	198	93	5	829377071f65016d31d09175a43c28e95532b404
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-SMG_Basal/Duct\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MISP DMKN PGM2L1 BCL2L1 ST14	5.96e-05	198	93	5	27a3c1c5ac855dff8d63f44eaa289be3f5bd621a
ToppCell	Tracheal-10x5prime-Stromal-Chondrocytic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LIFR CPAMD8 ANGPTL2 PALS2 CRISPLD1	5.96e-05	198	93	5	c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS2 ANGPTL2 DMKN CRISPLD1 FREM1	5.96e-05	198	93	5	12cd9f0bbad8dce5199ebfed1c4a8080710ca055
ToppCell	Tracheal-10x5prime-Stromal-Chondrocytic-Chondrocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LIFR CPAMD8 ANGPTL2 PALS2 CRISPLD1	5.96e-05	198	93	5	55f013e9e6587d9ece59751fa131b1d22d6cceea
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	LIFR THBS2 ANGPTL2 SEMA5A PTH1R	5.96e-05	198	93	5	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	Sigmoid-Dendritic_cell-cycling_DCs\|Sigmoid / Region, Cell class and subclass	CLEC9A CLEC4A DTL ADGRA2 ST14	6.10e-05	199	93	5	bd6f8c0f79e9a94cc0f8c6105d38851463de821c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	THBS2 HCAR1 KCNK17 ADGRA2 PTH1R	6.10e-05	199	93	5	dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	LIFR CPAMD8 THBD ACACB ADAMTS6	6.10e-05	199	93	5	bd43a84e84d8acb8e1008b98a235cc5bd5f43586
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD1E LIPA CLEC9A CLEC4A CD209	6.10e-05	199	93	5	c684530d4d8073337379c2a24e5e54297fb13691
ToppCell	Sigmoid-(5)_Dendritic_cell-(52)_cycling_DCs\|Sigmoid / shred on region, Cell_type, and subtype	CLEC9A CLEC4A DTL ADGRA2 ST14	6.10e-05	199	93	5	8ee78a39729633bcbb3ab17e1dfaca33f38db569
ToppCell	Bronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SEMA5A KCNK17 ADGRA2 PTH1R PREX2	6.10e-05	199	93	5	929f809579368201331d9099d8904b6e3c41797b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	THBS2 HCAR1 KCNK17 ADGRA2 PTH1R	6.10e-05	199	93	5	c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell	Bronchial-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SEMA5A KCNK17 ADGRA2 PTH1R PREX2	6.10e-05	199	93	5	854628ce91068093c14bd4d45ba38c41469f3549
ToppCell	Sepsis-URO-Lymphocyte-T/NK-CD8+_Tcm\|URO / Disease, condition lineage and cell class	KLRK1 ZP1 DMKN SEMA5A BCL2	6.10e-05	199	93	5	eb085f9f2c837494548c26bb61e8b74516539e23
ToppCell	Bronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SEMA5A KCNK17 ADGRA2 PTH1R PREX2	6.25e-05	200	93	5	12326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCell	Lung_Parenchyma-Control-Myeloid-cDC-DCs\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD1E CLEC9A CLEC4A BCL2 ST14	6.25e-05	200	93	5	0576e34dc9a6adae5782659511d641781c6a44ed
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-PENK-L1-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN ADAMTS6 WNT9B PAPLN SEMA5A	6.25e-05	200	93	5	08a00b0687bef5fef12bfa8e52ae4570071bae5e
ToppCell	Caecum-Dendritic_cell\|Caecum / Region, Cell class and subclass	THBD CD1E CLEC9A CLEC4A CD209	6.25e-05	200	93	5	b91d3d7505a022ca360ab5b3f9955753d111f974
ToppCell	Lung_Parenchyma-Control-Myeloid-cDC-DCs-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD1E CLEC9A CLEC4A BCL2 ST14	6.25e-05	200	93	5	b074b30cd7bb893c24cd49af1b2126825c59eef7
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-OPRM1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN CD5L ADAMTS6 PTH1R PREX2	6.25e-05	200	93	5	559cf4001a3f985c8357f0102b34fab2e34d2a04
ToppCell	Parenchyma_Control_(B.)-Immune-TX-DCs\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CD1E CLEC9A CLEC4A BCL2 ST14	6.25e-05	200	93	5	cae0e62804e41828e9cf74b9e3452c43a12bc87d
ToppCell	Lung_Parenchyma-Control-Myeloid-cDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD1E CLEC9A CLEC4A BCL2 ST14	6.25e-05	200	93	5	337daee31dd5a277b9ef1dbd7fd6660371636084
ToppCell	Bronchial-10x5prime-Stromal-Pericyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SEMA5A KCNK17 ADGRA2 PTH1R PREX2	6.25e-05	200	93	5	362706445edb33b313684efe50b1f44f5f816e67
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-PENK\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN ADAMTS6 WNT9B PAPLN SEMA5A	6.25e-05	200	93	5	266990ee2e835e98b92dfdf7e3114f9737ffa85e
ToppCell	Transverse-Dendritic_cell\|Transverse / Region, Cell class and subclass	THBD CD1E CLEC9A CLEC4A ST14	6.25e-05	200	93	5	b0e9eaf0e57e53645e272e2cea9f09bfcfe12a9b
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	THBS2 USP54 ZFP2 PTH1R FREM1	6.25e-05	200	93	5	29054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCell	Transverse-(5)_Dendritic_cell\|Transverse / shred on region, Cell_type, and subtype	THBD CD1E CLEC9A CLEC4A ST14	6.25e-05	200	93	5	6c32a64f7c38818b93eec1e2d41067e5dbd90541
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial-Astrocyte\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	LIFR ADAMTS6 TECPR2 SEMA5A PREX2	6.25e-05	200	93	5	7c66953ff6d8f16f4decd23c85232990d2d8c6c4
Disease	Colorectal Carcinoma	LIFR CPAMD8 ACACA DMKN DLG3 BCL2 STAM PREX2 ZNF572 NLRP8	6.19e-05	702	91	10	C0009402
Disease	muscular disease (implicated_via_orthology)	ACACA ACACB	9.35e-05	5	91	2	DOID:0080000 (implicated_via_orthology)
Disease	melanoma (is_marker_for)	EHMT2 BCL2 BCL2L1	1.45e-04	33	91	3	DOID:1909 (is_marker_for)
Disease	Liver carcinoma	LIFR TGM3 CD5L ACACA DTL KMT2A BCL2L1 PTH1R	1.75e-04	507	91	8	C2239176
Disease	Erectile dysfunction	BCL2 BCL2L1	4.17e-04	10	91	2	C0242350
Disease	tuberculosis (is_marker_for)	KLRK1 CD209	5.08e-04	11	91	2	DOID:399 (is_marker_for)
Disease	endometriosis (implicated_via_orthology)	BCL2 BCL2L1	5.08e-04	11	91	2	DOID:289 (implicated_via_orthology)
Disease	gastric ulcer (implicated_via_orthology)	BCL2 BCL2L1	8.36e-04	14	91	2	DOID:10808 (implicated_via_orthology)
Disease	impotence (implicated_via_orthology)	BCL2 BCL2L1	9.62e-04	15	91	2	DOID:1875 (implicated_via_orthology)
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	PPARGC1B ACACA ACACB	1.08e-03	65	91	3	DOID:0080208 (biomarker_via_orthology)
Disease	mitochondrial heteroplasmy measurement	SLC6A7 MGAM UNC13C	1.28e-03	69	91	3	EFO_0600008
Disease	anorectal malformation	THBS2 NLRP8	1.55e-03	19	91	2	MONDO_0019938
Disease	osteochondrodysplasia (is_implicated_in)	LIFR PTH1R	1.55e-03	19	91	2	DOID:2256 (is_implicated_in)
Disease	Dyschondroplasias	BCL2 PTH1R	1.55e-03	19	91	2	C0013366
Disease	Mood Disorders	RELN DLG3 PFKL SERTAD1	1.84e-03	168	91	4	C0525045
Disease	Leukemia, Myelocytic, Acute	EHMT2 CTC1 KMT2A BCL2	2.05e-03	173	91	4	C0023467
Disease	transitional cell carcinoma (is_implicated_in)	BCL2 BCL2L1	2.09e-03	22	91	2	DOID:2671 (is_implicated_in)
Disease	dilated cardiomyopathy (biomarker_via_orthology)	BCL2 BCL2L1	2.09e-03	22	91	2	DOID:12930 (biomarker_via_orthology)
Disease	acute myeloid leukemia (is_implicated_in)	KAT6A KMT2A BCL2	2.26e-03	84	91	3	DOID:9119 (is_implicated_in)
Disease	QRS duration	PPARGC1B CD1E KMT2A CORO7 RBM20	2.33e-03	298	91	5	EFO_0005055
Disease	Head Neoplasms	BCL2 BCL2L1	2.48e-03	24	91	2	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	BCL2 BCL2L1	2.48e-03	24	91	2	C0887900
Disease	Cancer of Head	BCL2 BCL2L1	2.48e-03	24	91	2	C0751177
Disease	Neck Neoplasms	BCL2 BCL2L1	2.69e-03	25	91	2	C0027533
Disease	Cancer of Neck	BCL2 BCL2L1	2.69e-03	25	91	2	C0746787
Disease	Acute monocytic leukemia	CTC1 KMT2A	2.91e-03	26	91	2	C0023465

Protein segments in the cluster

Peptide	Gene	Start	Entry
WDWRETGTEHSPGVQ	AAMDC	36	Q9H7C9
PGQDNPEWLISEDWA	EP400	2361	Q96L91
WNSSGEGHLELWDAP	CTC1	171	Q2NKJ3
GHEWVWLDSEQDHPN	BRD8	861	Q9H0E9
HWAEGAEPVAAWWSQ	ADGRA2	701	Q96PE1
DHLEPWIQENGGWDT	BCL2L1	176	Q07817
PVQAVWAGWGHASEN	ACACA	201	Q13085
QDSGGWTPIIWAAEH	EHMT2	781	Q96KQ7
WCDQRHDPGGWTVIQ	ANGPTL2	306	Q9UKU9
GPWGKNTCNHDEDTW	CD5L	221	O43866
LNQEGTWQWVDGSPL	CD209	321	Q9NNX6
AHWNAVFDLAWVPGE	DTL	96	Q9NZJ0
EIQGDWWSHGKALEP	C2orf73	76	Q8N5S3
GDNEVGFTWNHQPWS	ADAMTS6	836	Q9UKP5
RADWGNGRDSWEHSP	RBM20	666	Q5T481
AVWAGWGHASENPKL	ACACB	346	O00763
VVQWLEQHWQAGDGP	ACACB	2381	O00763
SGWGQDEPQTWPTDH	MISP	41	Q8IVT2
LWTPTDGGSWHVDQR	GRWD1	241	Q9BQ67
SLADQEWGLPSHWGA	MTMR11	601	A4FU01
EAPESNGLHRWWQDL	NLRP8	681	Q86W28
AGHWLGDNTAAWDQL	MGAM	2416	O43451
ATDPHSWWAGDNQQV	CORO7	366	P57737
THFWDENPQGVWTLG	PCSK4	541	Q6UW60
HWASRLGGTWQDPDK	KCNK17	161	Q96T54
EPWNGSWNDNLVDTS	PGM2L1	211	Q6PCE3
QVQEVGWHDVAGWLG	PFKL	446	P17858
GLVHIPTNGSWQWED	KLRK1	156	P26718
NDQVHAGHWEWIGGE	FREM1	2116	Q5H8C1
FHWDLPQALQDHGGW	LCT	496	P09848
WDGPEQEGDWSQQEL	KRI1	431	Q8N9T8
SHVPSAAAQGAWSWE	L3MBTL4	41	Q8NA19
GSAEQHSPAWDGWNR	TUBGCP6	846	Q96RT7
WQPRHDGLDQNDWAI	RELN	2641	P78509
WQPRHNGTGHDQWAL	RELN	3406	P78509
DWPTDNQDGWDGKQE	KAT6A	451	Q92794
DPNWWQASHVKEGGS	PALS2	256	Q9NZW5
CGIGGSHWPVDQTDW	PLA2G2E	46	Q9NZK7
SGWLGDLQTHGWDTV	CD1E	56	P15812
HNGWIDVTWDAGGSN	HECTD1	1306	Q9ULT8
SWQGVPGHNGAWETS	DMKN	131	Q6E0U4
AESWAESCLWEHGPA	CRISPLD1	96	Q9H336
GDPSLHGDVWSWLEF	EI24	106	O14681
WIWHCLNISDPSGEG	CPAMD8	751	Q8IZJ3
SWGEDGWVQLDQLPS	ADGRF2	56	Q8IZF7
DEWWQARLVTPHGES	DLG3	541	Q92796
TVETWWPHGHGNQTG	MANBA	286	O00462
PGKGWDAQWSHDFSL	KMT2A	1541	Q03164
QSQSDGQWDPHIVEW	HCAR1	331	Q9BXC0
GWFDSWGGPHNILDS	GLB1L2	281	Q8IW92
STEAWTGEWKQPHGG	SCNN1D	136	P51172
DGPEETDWWWAALHG	PPP1R13L	791	Q8WUF5
NLHFSGLEEWSDWSP	LIFR	226	P42702
PTWDLGNGAAWHWDL	OAS3	301	Q9Y6K5
GNGAAWHWDLLAQEA	OAS3	306	Q9Y6K5
WNVGHGSWELLAQEA	OAS3	706	Q9Y6K5
GTWWDEHLSEENVPF	MRPL3	46	P09001
PCWVTGWGDVDNNVH	TPSD1	161	Q9BZJ3
VQGHWAREAPGAWDC	THBD	231	P07204
QGNIPHSHDWVWLGN	TMEM132B	936	Q14DG7
AWHEGLDQCDPGWLA	NCAN	296	O14594
SWEPSGVHLEDWPQQ	PPARGC1B	711	Q86YN6
VDSWWLDPGHTAVAQ	SERTAD1	21	Q9UHV2
QLDEHAGWQWSDGTP	PLA2R1	296	Q13018
PEDWEGFQHTQGTWV	SPEM1	151	Q8N4L4
WDVHSSPGSWLEVQN	SP9	181	P0CG40
DLPWEHCGNWWNTEL	SLC6A7	151	Q99884
NLTVDGHFGVWSPWT	SEMA5A	536	Q13591
HVWNEGWFVRSDLGP	TGM3	331	Q08188
WNEDHWEQTLPGSSD	AATF	81	Q9NY61
HTWIQDNGGWDAFVE	BCL2	186	P10415
FTWNDQVHGTVGEPW	ASCC3	1206	Q8N3C0
GLSDPEGQRHWQWVD	CLEC4A	166	Q9UMR7
GLSQDGHSGRWLWQD	CLEC9A	176	Q6UXN8
LVNADGHGEVWTDWN	C11orf1	31	Q9H5F2
GDFPHEWTWKNCSGE	ZNF572	501	Q7Z3I7
TWGVWHVPELDTQDA	RINL	46	Q6ZS11
GEWPWQASLQWDGSH	TMPRSS11E	201	Q9UL52
EAGPHEGWSCQQIWE	ZNF223	91	Q9UK11
ATLAQPHWGTLEHWD	ZP1	206	P60852
HEDLSPWKEWNQGAD	UNC13C	651	Q8NB66
DTLEGGWPWQVSLHF	TMPRSS7	611	Q7RTY8
HTQAFGEWPWGQELG	PAPLN	871	O95428
NGSWELVPGHNRTWA	PTH1R	151	Q03431
TLVGNNHESWGWDLG	SPSB1	131	Q96BD6
VDHRGTWNGPWVSTE	SSR4	136	P51571
ADEGEWPWQVSLHAL	ST14	621	Q9Y5Y6
DDSDPNWWKGETHQG	STAM	241	Q92783
EWQSHIEGWEGSNIT	PREX2	226	Q70Z35
PQGDDDHWWQVSITD	TECPR2	1016	O15040
KWNSVDVCPWEDGNH	ZSWIM6	471	Q9HCJ5
HEWEQGAGWPGLATA	TEX13A	151	Q9BXU3
WEAFDTSLWSDGGPH	TEX13A	336	Q9BXU3
IWHSTLGETWEPNNW	ZFP2	6	Q6ZN57
HSVDGEEGWSPWAEW	THBS2	376	P35442
PGELGWENPNEWSQE	TMEM74	136	Q96NL1
WRWGENAHNVTLSPG	ZNF367	71	Q7RTV3
DDSPGLESRQAWQWG	WNT9B	146	O14905
ETGPHEEWSCQQIWE	ZNF284	91	Q2VY69
GWGQQDTAWHPLSQT	USP54	1336	Q70EL1
PTAVWSGGHDWLADV	LIPA	336	P38571