Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessvitellogenesis

FOSL1 SOS1

2.66e-054442GO:0007296
GeneOntologyBiologicalProcessaxon choice point recognition

ROBO1 EFNB3

1.59e-049442GO:0016198
GeneOntologyBiologicalProcesscell morphogenesis

ENAM ROBO1 NYAP2 EFNB3 SEPTIN7 NFIB FOSL2 NOTCH2 SIPA1L3 SOS1

1.66e-0411944410GO:0000902
GeneOntologyBiologicalProcessmulticellular organism growth

PPP1R13L FOSL2 NOTCH2 SOS1 ARID5B

1.82e-04249445GO:0035264
GeneOntologyBiologicalProcessepithelium development

ENAM ROBO1 ROS1 HDAC5 KDF1 NFIB FOSL2 NOTCH2 SIPA1L3 TRPS1 SOS1

1.97e-0414694411GO:0060429
GeneOntologyBiologicalProcessfat pad development

FOSL2 ARID5B

2.42e-0411442GO:0060613
GeneOntologyBiologicalProcessepithelial cell development

ROS1 KDF1 FOSL2 NOTCH2 SIPA1L3

2.60e-04269445GO:0002064
GeneOntologyBiologicalProcessaxon guidance

ROBO1 EFNB3 NFIB NOTCH2 SOS1

3.40e-04285445GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

ROBO1 EFNB3 NFIB NOTCH2 SOS1

3.45e-04286445GO:0097485
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

ROBO1 PPP1R13L NOTCH2 SOS1

3.81e-04161444GO:0003206
GeneOntologyBiologicalProcesseye development

SDK2 PPP1R13L NFIB NOTCH2 SIPA1L3 SOS1

5.13e-04480446GO:0001654
GeneOntologyBiologicalProcessvisual system development

SDK2 PPP1R13L NFIB NOTCH2 SIPA1L3 SOS1

5.30e-04483446GO:0150063
GeneOntologyBiologicalProcesssensory system development

SDK2 PPP1R13L NFIB NOTCH2 SIPA1L3 SOS1

5.78e-04491446GO:0048880
GeneOntologyBiologicalProcesskeratinocyte development

KDF1 FOSL2

5.93e-0417442GO:0003334
GeneOntologyBiologicalProcessdevelopmental growth

ROBO1 SEPTIN7 PPP1R13L KDF1 FOSL2 NOTCH2 SOS1 ARID5B

6.04e-04911448GO:0048589
MousePhenofailure of eyelid fusion

PPP1R13L NFIB TCF7L1

2.39e-0520403MP:0009264
MousePhenoabnormal eyelid fusion

PPP1R13L NFIB TCF7L1

7.53e-0529403MP:0009263
MousePhenoabnormal eyelid development

PPP1R13L NFIB TCF7L1

9.23e-0531403MP:0009651
DomainAP-1

FOSL2 FOSL1

2.02e-049452IPR000837
DomainbZIP_1

FOSL2 FOSL1

3.03e-0334452PF00170
DomainTF_DNA-bd

FOSL2 FOSL1

3.58e-0337452IPR008917
Domainfn3

ROBO1 ROS1 SDK2

6.96e-03162453PF00041
DomainBRLZ

FOSL2 FOSL1

6.97e-0352452SM00338
DomainBZIP

FOSL2 FOSL1

7.23e-0353452PS50217
DomainBZIP_BASIC

FOSL2 FOSL1

7.23e-0353452PS00036
DomainbZIP

FOSL2 FOSL1

7.50e-0354452IPR004827
DomainFN3

ROBO1 ROS1 SDK2

1.00e-02185453SM00060
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

SDK2 ZFC3H1 VWA7 PPP1R13L PRRC2A SIPA1L3 EIF4B

3.96e-0736145726167880
Pubmed

ROS1 signaling regulates epithelial differentiation in the epididymis.

ROS1 SOS1

1.64e-06245224971615
Pubmed

Multiple cis-elements mediate the transcriptional activation of human fra-1 by 12-O-tetradecanoylphorbol-13-acetate in bronchial epithelial cells.

FOSL2 FOSL1

1.64e-06245213679379
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DLAT ROBO1 ZFC3H1 SEPTIN7 MPPED2 PRRC2A SIPA1L3 TRPS1 SOS1 ARID5B

4.49e-061285451035914814
Pubmed

Interaction of AP-1 with a cluster of NF-kappa B binding elements in the human TNF promoter region.

FOSL2 FOSL1

4.91e-06345211708771
Pubmed

A systematic comparison of FOSL1, FOSL2 and BATF-mediated transcriptional regulation during early human Th17 differentiation.

FOSL2 FOSL1

4.91e-06345235511484
Pubmed

Isolation of human fos-related genes and their expression during monocyte-macrophage differentiation.

FOSL2 FOSL1

4.91e-0634522107490
Pubmed

Semaphorin heterodimerization in cis regulates membrane targeting and neocortical wiring.

ROBO1 EFNB3 NFIB

5.15e-062645339152101
Pubmed

Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis.

FOSL2 FOSL1

9.81e-06445230990796
Pubmed

AP-1 transrepressing retinoic acid does not deplete coactivators or AP-1 monomers but may target specific Jun or Fos containing dimers.

FOSL2 FOSL1

1.63e-05545211948401
Pubmed

TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer.

TRPS1 FOSL1

1.63e-05545221673316
Pubmed

Cross-family interaction between the bHLHZip USF and bZip Fra1 proteins results in down-regulation of AP1 activity.

FOSL2 FOSL1

1.63e-0554529160889
Pubmed

Liver cancer development driven by the AP-1/c-Jun~Fra-2 dimer through c-Myc.

FOSL2 FOSL1

1.63e-05545238657045
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DLAT ROBO1 SEPTIN7 PRC1 PPP1R13L PRRC2A DEPDC1B SOS1

2.04e-0591645832203420
Pubmed

Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.

NYAP2 PRC1 NOTCH2

2.08e-054145320889853
Pubmed

Tissue-specific expression of the fos-related transcription factor fra-2 during mouse development.

FOSL2 FOSL1

2.45e-0564527700631
Pubmed

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells.

ROBO1 HDAC5

2.45e-05645219351956
Pubmed

A genome-wide association study of early menopause and the combined impact of identified variants.

NYAP2 PRRC2A

3.42e-05745223307926
Pubmed

Binding site specificity and factor redundancy in activator protein-1-driven human papillomavirus chromatin-dependent transcription.

FOSL2 FOSL1

4.56e-05845221937452
Pubmed

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

MAP7D2 EFNB3 PRC1 NOTCH2 ZNF503

4.75e-0530745537499664
Pubmed

Single-cell transcriptomics of the early developing mouse cerebral cortex disentangle the spatial and temporal components of neuronal fate acquisition.

MPPED2 NFIB ZNF503

5.35e-055645334170322
Pubmed

Trophoblast stem cell maintenance by fibroblast growth factor 4 requires MEKK4 activation of Jun N-terminal kinase.

FOSL2 FOSL1

5.86e-05945219289495
Pubmed

Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2.

ROBO1 NOTCH2

5.86e-05945223144817
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

MPHOSPH9 PRRC2A NOTCH2 SIPA1L3 EIF4B SOS1

6.37e-0553645615840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

MPHOSPH9 PRRC2A NOTCH2 SIPA1L3 EIF4B SOS1

6.51e-0553845610512203
Pubmed

Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain.

PRC1 MPPED2 ZNF503

6.58e-056045335175194
Pubmed

Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers.

FOSL2 FOSL1

7.32e-051045224411941
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

SEPTIN7 PPP1R13L KDF1 NOTCH2 SIPA1L3 EIF4B

8.51e-0556545625468996
Pubmed

Interaction network of human early embryonic transcription factors.

HDAC5 NFIB ZNF503 TRPS1 ARID5B

8.93e-0535145538297188
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DLAT MAP7D2 ROBO1 CCPG1 FAM193A ZFC3H1 DEPDC1B NOTCH2 SYNE2

1.03e-04148745933957083
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

FCHSD2 MPHOSPH9 NYAP2 EIF4B ARID5B

1.26e-0437845534315543
Pubmed

Association of polymorphisms in the SLIT2 axonal guidance gene with anger in suicide attempters.

ROBO1 EFNB3

1.47e-041445220029409
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

ROBO1 FAM193A PPP1R13L SIPA1L3

1.56e-0420945436779422
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NFIB SYNE2 ZNF503 TRPS1 ARID5B

1.60e-0439845535016035
Pubmed

Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.

NFIB NOTCH2 TRPS1

1.67e-048245331073041
Pubmed

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation.

TCF7L1 FOSL1

1.70e-041545215866165
Pubmed

Identification of candidate genes at the corticoseptal boundary during development.

NFIB NOTCH2

1.70e-041545216458080
Pubmed

The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord.

ROBO1 EFNB3

2.47e-041845216854408
Pubmed

Notch Signaling Pathway in Tooth Shape Variations throughout Evolution.

TCF7L1 NOTCH2

2.47e-041845236899896
Pubmed

Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins.

FOSL2 FOSL1

2.47e-04184529858769
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

MPHOSPH9 FAM193A HDAC5 NOTCH2 SIPA1L3

2.72e-0444645524255178
Pubmed

Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.

ROBO1 NOTCH2

2.76e-041945225691540
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ROBO1 MPHOSPH9 SEPTIN7 PRRC2A DEPDC1B EIF4B

2.89e-0470845639231216
Pubmed

The transcription factor neurogenin 2 restricts cell migration from the cortex to the striatum.

ROBO1 EFNB3

3.06e-042045211748150
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

XYLT2 FAM193A HNRNPLL PRRC2A NFIB

3.19e-0446245531138677
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ZFC3H1 HDAC5 SIPA1L3

3.46e-041054539628581
Pubmed

Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry.

ROBO1 SEPTIN7 NOTCH2

3.56e-0410645338891874
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ROBO1 MPHOSPH9 PPP1R13L PRRC2A SIPA1L3 SYNE2 TRPS1

3.71e-04104945727880917
Pubmed

TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors.

TCF7L1 NOTCH2

3.72e-042245217919533
Pubmed

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.

SEPTIN7 PRC1 PRRC2A

3.76e-0410845319531213
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NFIB FOSL2 TRPS1 ARID5B

4.01e-0426845433640491
Pubmed

Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.

ROBO1 EFNB3

4.07e-042345224360543
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

DLAT VWA7 PRRC2A TRPS1 ARID5B

4.41e-0449645531343991
Pubmed

Human transcription factor protein interaction networks.

DLAT HDAC5 PRRC2A NFIB SYNE2 ZNF503 TRPS1 ARID5B

4.42e-04142945835140242
Pubmed

Dentate gyrus morphogenesis is regulated by β-catenin function in hem-derived fimbrial glia.

NFIB TCF7L1

4.82e-042545236196585
Pubmed

Brain development is impaired in c-fos -/- mice.

FOSL2 FOSL1

4.82e-042545226143639
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

PRC1 HNRNPLL PRRC2A FOSL2 EIF4B ZNF503 FOSL1

5.01e-04110345734189442
Pubmed

Robo1 modulates proliferation and neurogenesis in the developing neocortex.

ROBO1 NOTCH2

5.63e-042745224741061
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ZFC3H1 HNRNPLL PRRC2A NFIB FOSL2 SIPA1L3 EIF4B TRPS1

6.01e-04149745831527615
Pubmed

The transcription factor gene Nfib is essential for both lung maturation and brain development.

ROBO1 NFIB

6.96e-043045215632069
Pubmed

c-Jun is required for the specification of joint cell fates.

FOSL2 FOSL1

7.43e-043145223475960
Pubmed

Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.

PRC1 PRRC2A EIF4B TRPS1

7.88e-0432145432098917
Pubmed

Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions.

DLAT EIF4B

7.92e-043245219542561
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MPHOSPH9 DEPDC1B NOTCH2 SIPA1L3 EIF4B SYNE2

8.09e-0486145636931259
Pubmed

Development and application of a DNA microarray-based yeast two-hybrid system.

ZFC3H1 HNRNPLL FOSL1

8.17e-0414145323275563
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

MAP7D2 PRRC2A FOSL2 TRPS1

8.92e-0433245437433992
Pubmed

Regulation of prefrontal patterning and connectivity by retinoic acid.

ROBO1 EFNB3

8.94e-043445234599305
Pubmed

Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly.

MPHOSPH9 FAM193A

1.12e-033845236674791
Pubmed

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.

ROBO1 PRRC2A EIF4B

1.16e-0315945330581152
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

ROBO1 NFIB NOTCH2 SYNE2

1.18e-0335845432460013
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

CCPG1 FAM193A TRPS1 ARID5B

1.24e-0336345414691545
GeneFamilyBasic leucine zipper proteins|Fos transcription factor family

FOSL2 FOSL1

1.19e-0542621256
GeneFamilyFibronectin type III domain containing

ROBO1 ROS1 SDK2

1.52e-03160263555
GeneFamilyBasic leucine zipper proteins

FOSL2 FOSL1

2.24e-0349262506
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ROBO1 SDK2

2.23e-02161262593
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2

ROBO1 CCPG1 SDK2 FAM193A HDAC5 PRRC2A NFIB TCF7L1 ZNF503 TRPS1 ARID5B

3.27e-0512084511facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NYAP2 PRC1 KDF1 DEPDC1B

2.31e-051654544297588f809e8a8275ab1a6ed99daac7ad93bd61
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRC1 HNRNPLL DEPDC1B SYNE2

2.84e-051744549d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRC1 HNRNPLL DEPDC1B SYNE2

2.84e-0517445453cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

EFNB3 PRRC2A SIPA1L3 FOSL1

2.91e-051754542812ac2ef41d245db544697fb6da1883361c96e8
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-Treg|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HNRNPLL SYNE2 TRPS1 ARID5B

3.32e-05181454a6c8b33a392de3df2f179317e329e45d3d8c6f52
ToppCellControl-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

ROBO1 MPPED2 FOSL1 UGT2A1

3.61e-05185454d5d6d13e2f20b54ca55645b9a757b8599f4fd897
ToppCellCF|World / Disease state, Lineage and Cell class

MMP25 FOSL2 SYNE2 FOSL1

3.77e-05187454eec4d4e4a658e3a61c05745167a1a5e3d39bb43e
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SDK2 PPP1R13L SIPA1L3 SYNE2

3.77e-0518745458d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCelldroplet-Thymus-nan-18m-Myeloid-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL10 KDF1 NFIB ZNF503

3.77e-05187454ed69e7cbd6fb59363b0e26f24887fc49405397ce
ToppCellE12.5-Mesenchymal|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEPTIN7 MPPED2 NFIB ZNF503

3.85e-051884549778dadc2bd7ded3a723e717d1c8cd3160e99c6c
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIB SYNE2 TRPS1 ARID5B

3.85e-05188454d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellILEUM-inflamed-(5)_Plasma-(5)_IgA_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ENAM CCPG1 EIF4B ARID5B

3.93e-05189454a0634d72bfdd5f93877724ed6480b50a3a046f71
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MPPED2 NFIB TCF7L1 SIPA1L3

4.09e-051914543e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellCOPD-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

HNRNPLL SYNE2 TRPS1 ARID5B

4.09e-051914543ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ROBO1 MPPED2 NFIB TRPS1

4.18e-05192454d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCellfacs-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R13L NFIB NOTCH2 FOSL1

4.18e-051924541f81b356520b5506051383d37fae204d59795336
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ROBO1 NFIB NOTCH2 TRPS1

4.53e-05196454dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Mesenchymal-skeletal_muscle_satellite_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIB NOTCH2 FOSL1 ARID5B

4.53e-0519645497ac47daf5bb07fa5dda3976e1ae402750f959b5
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MMP25 CCPG1 FOSL2 SYNE2

4.71e-05198454e76061e66f6d60f5735962aa7777dda8958caed9
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MMP25 CCPG1 FOSL2 SYNE2

4.80e-0519945486f2857ce60fbe59375411373ff49c684fd66ad0
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

FCHSD2 SIPA1L3 TRPS1 SOS1

4.80e-0519945494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

PRC1 NFIB TCF7L1 SYNE2

4.80e-051994548e72efcd421639ac36ed036ee13f13de070d361f
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EFNB3 MPPED2 NFIB ZNF503

4.80e-051994544217b9e66c5374461e84bdb893ab650f148286c8
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells-Neuroepithelial_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

PRC1 DEPDC1B NFIB SYNE2

4.89e-052004548f8b8c225cdc79baf16fe04be89bdb65e404a055
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells|10w / Sample Type, Dataset, Time_group, and Cell type.

PRC1 DEPDC1B NFIB SYNE2

4.89e-05200454a1f48eca9efb4f3ec3c9ace20f8c9257dd72c4ed
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ROBO1 NFIB SYNE2 ZNF503

4.89e-052004543dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

PRC1 MPPED2 DEPDC1B SYNE2

4.89e-052004540d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

PRC1 NFIB TCF7L1 SYNE2

4.89e-052004547c495030e6566b81d97b5516d1972e335ce5ed8c
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Neuron|2m / Sample Type, Dataset, Time_group, and Cell type.

ROBO1 MPPED2 NFIB SRRM4

4.89e-05200454a581f1704a87b0390e1e2ff85053367d85247755
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells|2m / Sample Type, Dataset, Time_group, and Cell type.

PRC1 MPPED2 DEPDC1B SYNE2

4.89e-052004540675f580ccef705875854247bbfd4ee2bcf126a1
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Ccnb1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PRC1 VWA7 DEPDC1B

2.99e-04129453ff74d159034a09f7b174da18bfb9a26936252b4c
ToppCellControl-Hematopoietic_Mast-Mast_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP25 ARSK FOSL1

3.96e-04142453a81f7ea4516a869c7c9b9a3f4ef74844ff9fffcd
ToppCellControl-Hematopoietic_Mast-Mast_cells-T-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP25 ARSK FOSL1

3.96e-0414245370f8c1be134835e0d21e6d426b7122f0f5d3d3e5
ToppCellControl-Hematopoietic_Mast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP25 ARSK FOSL1

3.96e-04142453db9b7acbab730ae391a362f1ca8177507e52250d
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ENAM FCHSD2 SIPA1L3

5.12e-041554539f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MPPED2 ZNF503 FOSL1

5.31e-04157453f896997490bb2eec598c6581f161220e70f9a991
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MPPED2 ZNF503 FOSL1

5.31e-0415745314a8516346a89a89f1119b744625bd9844a74a03
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

MAP7D2 FCHSD2 TRPS1

5.41e-041584531f94622186d8329357fa06785e03eeacf29ab1ce
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SDK2 DEPDC1B SRRM4

5.61e-041604532d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCellICU-NoSEP-Lymphocyte-T_NK-gdT|ICU-NoSEP / Disease, Lineage and Cell Type

VWA7 SYNE2 ARID5B

5.61e-041604532798c5bd971407f27dd4d3a4831d63d9c88003c3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SDK2 DEPDC1B SRRM4

5.61e-041604538bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCellBasal_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

MAP7D2 SDK2 PPP1R13L

5.61e-04160453b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 SEPTIN7 NFIB

5.82e-0416245358da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 SEPTIN7 NFIB

5.82e-041624534d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NYAP2 MASP2 SOS1

5.92e-04163453132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MPHOSPH9 PRC1 DEPDC1B

5.92e-041634535285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell5'-Adult-Appendix-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENAM FCHSD2 CCPG1

6.14e-0416545379c6ad394266ff092029375883660028e944a3c8
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

MMP25 SDK2 ZNF503

6.25e-04166453773673a5d0430640439845b264740bfbbdad0cb2
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

MMP25 SDK2 ZNF503

6.36e-041674533ae46c6363da76c8e1f5579e6027bf88ed637a44
ToppCellCOVID-19_Moderate-Treg|COVID-19_Moderate / disease group, cell group and cell class

HNRNPLL SYNE2 ARID5B

6.36e-041674534ddb21421cbe72c06b61dd3a5eb1337e59de42e5
ToppCellfacs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA7 NFIB TCF7L1

6.36e-0416745378909f685ccd1321064eb0887caf9263e0e54879
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PRC1 MPPED2 DEPDC1B

6.36e-041674533461d14e36f09ddc6ee5549ca4797e16d3f37fcc
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

HDAC5 NOTCH2 EIF4B

6.47e-04168453c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 CCPG1 FOSL2

6.58e-04169453e0076aa61b4ef3f836f5750005d0469d3982eb6d
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 CCPG1 FOSL2

6.58e-04169453a5964aef04093b460bbe29d5e2e7389f8fd2d46f
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 CCPG1 FOSL2

6.58e-041694532341eddfedaad8cee779c37bb87f7def058588ca
ToppCellCOVID-19_Moderate-Treg|World / disease group, cell group and cell class

HNRNPLL SYNE2 ARID5B

6.58e-0416945327ad11239559b025bef582f89b2a83501d9d3993
ToppCellfacs-Marrow-Granulocytes-18m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 CCPG1 FOSL2

6.58e-0416945394871936ccfc73b56d425373b989b87c059d4493
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Monocytes|normal_Pleural_Fluid / Location, Cell class and cell subclass

MMP25 FOSL2 FOSL1

6.58e-041694537b71463f0fd802b422c8d394a435901009ca200f
ToppCellBL-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ROBO1 SDK2 SRRM4

6.69e-04170453b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCellBasal_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

SDK2 MPPED2 TCF7L1

6.69e-04170453776d4224a682b6c648041827efd69794f88906f0
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 CCPG1 FOSL2

6.81e-04171453ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-mature_conventional_dendritic_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EFNB3 TCF7L1 ZNF503

6.81e-04171453d934d68efc5739483c735dc702ccd30b07a6aa7e
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

SYNE2 MASP2 ARID5B

6.81e-0417145361318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 CCPG1 FOSL2

6.81e-0417145397ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EFNB3 FOSL1 ARID5B

6.92e-04172453bd73fd3520064d430a153cfdd5c2858b6c184c59
ToppCelldroplet-Marrow-nan-3m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 CCPG1 FOSL1

6.92e-04172453cfcfa7eeff1805bedf10a3c07826459914c3e872
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EFNB3 FOSL1 ARID5B

6.92e-0417245347ee78ed3ba6516dad8f12dbf70bca5ed1c60aff
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SDK2 DEPDC1B SRRM4

7.04e-041734534bc6d93716f093b460c8b047199db8cab5fea720
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOSL2 NOTCH2 FOSL1

7.04e-041734530f9c1d3298e59e6d22bb3306f0f445f490be8bbd
ToppCell10x5'-blood-Lymphocytic_Invariant-Inducer-like|blood / Manually curated celltypes from each tissue

TTLL10 MPPED2 SYNE2

7.16e-0417445351be6f29308c01593978cbee92114151a5916c9c
ToppCellCOPD-Myeloid-pDC|World / Disease state, Lineage and Cell class

ENAM FCHSD2 SDK2

7.16e-04174453be8227398300711ccda5ecc41ad34064bb246b19
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROS1 SDK2 NFIB

7.16e-041744537d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROS1 NYAP2 TRPS1

7.16e-04174453ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellHealthy_donor-Treg|Healthy_donor / disease group, cell group and cell class (v2)

HNRNPLL SYNE2 ARID5B

7.16e-041744531d76921c8404b5be5fbe9f3157d53578033f2ad2
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PRC1 MPPED2 DEPDC1B

7.28e-04175453cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP7D2 SEPTIN7 PRC1

7.28e-04175453fa16c6ba08dc0cc22e8cf049db0577811d080df6
ToppCell10x_5'_v1-Neoplastic-Stem-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PRC1 MPPED2 DEPDC1B

7.28e-04175453a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ENAM FCHSD2 SDK2

7.28e-0417545337c2d4e0b6e9a3171931797ce9a54f3347288e57
ToppCellfacs-Skin-Anagen-24m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA7 NFIB TCF7L1

7.28e-041754535552ff1e13f931c8cd7780726c90b5609497a648
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDK2 EFNB3 MPPED2

7.28e-04175453f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCellIPF-Myeloid-pDC|World / Disease state, Lineage and Cell class

ENAM FCHSD2 SDK2

7.28e-04175453a06785a4ded01adfd29ca4c20f7759eccbe274cb
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PRC1 MPPED2 DEPDC1B

7.28e-041754538a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDK2 EFNB3 MPPED2

7.28e-041754537bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PRC1 MPPED2 DEPDC1B

7.28e-04175453378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDK2 MPPED2 CCER1

7.40e-0417645377c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCellControl-Myeloid-pDC|Control / Disease state, Lineage and Cell class

ENAM FCHSD2 SDK2

7.52e-041774533940663bb5b45b2ca9f772550380a516c53e410b
ToppCellControl-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

ENAM FCHSD2 SDK2

7.52e-04177453e82115bfc32c7b689460fbc5caeb983c1aabe30f
ToppCellCOPD-Myeloid-pDC|COPD / Disease state, Lineage and Cell class

ENAM FCHSD2 SDK2

7.52e-04177453415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-MEP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MAP7D2 ROBO1 TTLL10

7.65e-04178453b8c301d65c0f37941e8e9414d55e90edb6ecc195
ToppCellIPF-Myeloid-pDC|IPF / Disease state, Lineage and Cell class

ENAM FCHSD2 SDK2

7.65e-041784538d9e28492e1f157bac3308aa947fd864ca16d277
ToppCellControl-Myeloid-pDC|World / Disease state, Lineage and Cell class

ENAM FCHSD2 SDK2

7.65e-0417845320ef63d925e67ddd5955832312ca8574a6f838a4
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EFNB3 SYNE2 ARID5B

7.65e-0417845390dedb3cef9b01907b9f8eec64218d6d2072be1f
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EFNB3 SYNE2 ARID5B

7.65e-04178453d6312286bf6cc5b107ccd7adb583d9667d4e1d21
ToppCellCOPD-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

ENAM FCHSD2 SDK2

7.77e-0417945329b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TTLL10 KDF1 SIPA1L3

7.77e-04179453ca70a5518c5a5392e088c103e0cb44aa084f5332
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MPPED2 NFIB ARID5B

7.77e-04179453d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TTLL10 KDF1 SIPA1L3

7.77e-04179453c451b074b04eb5d6c575c6abaedda579c6744bbf
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HNRNPLL SYNE2 ARID5B

7.90e-041804536bb9f41c3a99d1bbe697f589fb2bcea9b7bfbeee
ToppCellIPF-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

ENAM FCHSD2 SDK2

7.90e-041804530f8567aa835d4e3a52f6631ae15216eca18a030c
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

MPPED2 NFIB FOSL2 TRPS1 FOSL1

1.82e-051654556085_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

MPPED2 NFIB FOSL2 TRPS1 FOSL1

2.10e-051704557043_DN
Drug15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A_EA

FCHSD2 ZFC3H1 MPPED2 NFIB ARID5B

2.55e-051774551069_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

MPPED2 NFIB FOSL2 TRPS1 SOS1

2.62e-051784551471_DN
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

MPHOSPH9 MPPED2 NFIB TRPS1 ARID5B

2.99e-051834555613_DN
Drugcelastrol; Down 200; 2.5uM; MCF7; HT_HG-U133A_EA

FCHSD2 MPHOSPH9 MPPED2 SIPA1L3 TRPS1

3.32e-05187455887_DN
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

FCHSD2 MPPED2 NOTCH2 SIPA1L3 ARID5B

3.40e-051884556451_DN
DrugAcebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; PC3; HG-U133A

XYLT2 EFNB3 FOSL2 NOTCH2 SIPA1L3

4.05e-051954551911_UP
DrugHesperetin [520-33-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A

MMP25 HDAC5 PRRC2A NOTCH2 SIPA1L3

4.15e-051964555350_UP
DrugDydrogesterone [152-62-5]; Down 200; 12.8uM; MCF7; HT_HG-U133A

XYLT2 MPPED2 NFIB NOTCH2 SIPA1L3

4.15e-051964552811_DN
Drugalpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A

ROBO1 FCHSD2 EFNB3 FOSL2 FOSL1

4.25e-051974551635_UP
DrugNalbuphine hydrochloride [23277-43-2]; Down 200; 10.2uM; PC3; HT_HG-U133A

FCHSD2 MPHOSPH9 EFNB3 HDAC5 SIPA1L3

4.57e-052004552063_DN
DrugAir Pollutants

MPLKIP ROBO1 FCHSD2 CCPG1 NOTCH2 EIF4B SYNE2 SOS1 ARID5B

6.43e-05917459ctd:D000393
Diseaserenal carcinoma (biomarker_via_orthology)

FOSL2 FOSL1

2.17e-055442DOID:4451 (biomarker_via_orthology)
DiseaseAlzheimer disease, dementia, family history of Alzheimer’s disease

ROBO1 HNRNPLL TRPS1

5.11e-0548443EFO_0009268, MONDO_0001627, MONDO_0004975
Diseaseserum gamma-glutamyl transferase measurement

ROBO1 NYAP2 KDF1 PRRC2A NFIB FOSL2 NOTCH2 SIPA1L3

5.42e-05914448EFO_0004532
Diseaselow density lipoprotein particle size measurement

NYAP2 KDF1 TRPS1

9.01e-0558443EFO_0008593
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

NYAP2 KDF1 SYNE2 TRPS1

1.10e-04166444EFO_0004530, EFO_0004611
Diseasecervical carcinoma

NYAP2 VWA7 PRRC2A TCF7L1

1.57e-04182444EFO_0001061
DiseaseMalignant neoplasm of breast

MPLKIP MAP7D2 ROBO1 PRC1 PRRC2A TCF7L1 NOTCH2 SYNE2

1.66e-041074448C0006142
Diseasealbumin:globulin ratio measurement

FCHSD2 MPHOSPH9 PRRC2A

1.79e-0473443EFO_0005128
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

NYAP2 KDF1 SYNE2 TRPS1

3.46e-04224444EFO_0004530, EFO_0008317
DiseaseSystemic Scleroderma

XYLT2 HDAC5

3.66e-0419442C0036421
DiseaseLEOPARD Syndrome

PPP1R13L SOS1

4.93e-0422442C0175704
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

NYAP2 SYNE2 TRPS1

6.13e-04111443EFO_0004530, EFO_0008595
Diseasecolon adenocarcinoma (is_marker_for)

FOSL2 FOSL1

6.38e-0425442DOID:234 (is_marker_for)
Diseasecortical surface area measurement

ROBO1 MPHOSPH9 NYAP2 MPPED2 PRRC2A NFIB TCF7L1 SOS1

7.47e-041345448EFO_0010736
Diseasebody fat percentage

ENAM NYAP2 PRRC2A NFIB TRPS1

7.74e-04488445EFO_0007800
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Positive

FCHSD2 ZFC3H1 FOSL2

9.91e-04131443C4704862
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Negative

FCHSD2 ZFC3H1 FOSL2

9.91e-04131443C4552091
DiseaseJuvenile arthritis

FCHSD2 ZFC3H1 FOSL2

9.91e-04131443C3495559
DiseaseJuvenile psoriatic arthritis

FCHSD2 ZFC3H1 FOSL2

9.91e-04131443C3714758
Diseasehemoglobin A1 measurement

NYAP2 PRC1 NOTCH2 SYNE2 TRPS1

1.03e-03520445EFO_0007629
DiseaseJuvenile-Onset Still Disease

FCHSD2 ZFC3H1 FOSL2

1.08e-03135443C0087031
Diseasesystemic lupus erythematosus

FCHSD2 NYAP2 FAM193A SRRM4 NOTCH2 ARID5B

1.14e-03799446MONDO_0007915
Diseaseovarian carcinoma

NYAP2 TTLL10 PRC1 HNRNPLL

1.32e-03321444EFO_0001075
Diseasetongue squamous cell carcinoma (is_marker_for)

FOSL2 FOSL1

1.40e-0337442DOID:0050865 (is_marker_for)
DiseaseTakayasu arteritis

ROBO1 VWA7 PRRC2A

1.41e-03148443EFO_1001857

Protein segments in the cluster

PeptideGeneStartEntry
YLGLNLPHPYPSPSS

ARSK

201

Q6UWY0
RHLYRFPPSSPLKPY

DEPDC1B

101

Q8WUY9
PHRYSPKTEYGPPRK

CCER1

51

Q8TC90
LYATPPFTHSKALPP

FAM193A

476

P78312
PAPSSYFSHPTIRYP

NFIB

376

O00712
YGSHGPLLPLPSRYR

HNRNPLL

291

Q8WVV9
PIPYDTPKPAGHTRF

MPPED2

46

Q15777
LTRYGYLPPPHPAQA

MMP25

36

Q9NPA2
PAYHPFPASVGKYPT

NOTCH2

2371

Q04721
TPPYGPRSRPYGSSH

MPLKIP

51

Q8TAP9
PYPGSPVKYRLPALS

MAP7D2

311

Q96T17
PGRRYYSLPPHQKVP

DLAT

81

P10515
LPGFPKYPSHTKASP

MPHOSPH9

351

Q99550
PPSTLYRTQSPHGYP

NYAP2

416

Q9P242
HTFSPPYGPRSVYIK

CCPG1

736

Q9ULG6
YPRSHPYSPLPGLAS

FOSL2

76

P15408
SDTAAKPLGRPYPPY

GLMP

136

Q8WWB7
LSSPEYPRPYPKLSS

MASP2

196

O00187
VARPGNPVYHKAYPP

ENAM

371

Q9NRM1
PYPSPDKRSSLYFPR

FCHSD2

666

O94868
PSYKLPLPGPYDSRD

HDAC5

236

Q9UQL6
RPPGPHSSPNYEFYK

EFNB3

66

Q15768
YTRSPPRPSPGSLHY

SDK2

2011

Q58EX2
LHPYSPLSPKGRPSS

PPP1R13L

106

Q8WUF5
PHFLGPSSYPRPLTY

FOSL1

56

P15407
PKSPPYTAFLGNLPY

EIF4B

91

P23588
PASSTPYKPPYGKLL

SYNE2

6481

Q8WXH0
YHSPVSRLPPSGSKP

PRC1

511

O43663
PGTPSLHPYRSQPLY

PRRC2A

1866

P48634
RYKPSPERYTAAPHP

SIPA1L3

1171

O60292
LKGIPVYPYPRATSP

KDF1

166

Q8NAX2
YSYPLKSPGVRPSNP

SOS1

1031

Q07889
SSYPYGSPPPLISKK

ARID5B

706

Q14865
KHPNYSPPGSPIEKY

TRPS1

1076

Q9UHF7
HPSELSPYYPLSPGA

TCF7L1

226

Q9HCS4
YSPEYPGPSHRIKKT

SEPTIN7

76

Q16181
SARKRPIPYYRPSPS

SRRM4

511

A7MD48
LQLYSPPSPSYRTHP

ROS1

176

P08922
PPRPISPPHTYGYIS

ROBO1

1301

Q9Y6N7
RYHPYSKSPLPTPGA

ZNF503

601

Q96F45
LLTSGYFGTHPPKPP

VWA7

226

Q9Y334
KHCGKVPYPPSYVPA

UGT2A1

181

P0DTE4
GKPSPHSTRPGPFFY

TTLL10

146

Q6ZVT0
PSSYRPKEPFRSHPP

ZFC3H1

101

O60293
HLYGSYPPGTPALKA

XYLT2

521

Q9H1B5