Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	laminin-3 complex	LAMA3 LAMB2	3.03e-05	3	67	2	GO:0005608
GeneOntologyCellularComponent	extracellular matrix	MEGF6 ABI3BP ADAMTS7 PTPRZ1 LAMA3 LAMB2 LAMC3 DMBT1 COLQ USH2A	4.27e-05	656	67	10	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	MEGF6 ABI3BP ADAMTS7 PTPRZ1 LAMA3 LAMB2 LAMC3 DMBT1 COLQ USH2A	4.38e-05	658	67	10	GO:0030312
GeneOntologyCellularComponent	basement membrane	LAMA3 LAMB2 LAMC3 COLQ USH2A	4.51e-05	122	67	5	GO:0005604
GeneOntologyCellularComponent	collagen-containing extracellular matrix	MEGF6 ABI3BP PTPRZ1 LAMA3 LAMB2 LAMC3 DMBT1 COLQ USH2A	4.68e-05	530	67	9	GO:0062023
GeneOntologyCellularComponent	synaptic cleft	GRIP1 LAMB2 COLQ	1.60e-04	33	67	3	GO:0043083
GeneOntologyCellularComponent	laminin complex	LAMA3 LAMB2	4.48e-04	10	67	2	GO:0043256
HumanPheno	Unfavorable response of muscle weakness to acetylcholine esterase inhibitors	LAMB2 COLQ	1.62e-05	2	21	2	HP:0030203
HumanPheno	Weak cry	LAMA3 LAMB2 SIM1 COLQ	4.01e-05	49	21	4	HP:0001612
HumanPheno	Abnormal cry	LAMA3 LAMB2 SIM1 COLQ	9.57e-05	61	21	4	HP:0025429
HumanPheno	Prolonged miniature endplate currents	LAMB2 COLQ	9.67e-05	4	21	2	HP:0003436
HumanPheno	Limited wrist extension	LAMB2 COLQ	9.67e-05	4	21	2	HP:0006251
Domain	Laminin_EGF	MEGF6 MEGF8 LAMA3 LAMB2 LAMC3 USH2A STAB1	3.08e-11	35	66	7	PF00053
Domain	EGF_Lam	MEGF6 MEGF8 LAMA3 LAMB2 LAMC3 USH2A STAB1	3.08e-11	35	66	7	SM00180
Domain	Laminin_EGF	MEGF6 MEGF8 LAMA3 LAMB2 LAMC3 USH2A STAB1	5.74e-11	38	66	7	IPR002049
Domain	EGF_LAM_2	MEGF8 LAMA3 LAMB2 LAMC3 USH2A STAB1	8.57e-10	30	66	6	PS50027
Domain	EGF_LAM_1	MEGF8 LAMA3 LAMB2 LAMC3 USH2A STAB1	8.57e-10	30	66	6	PS01248
Domain	Laminin_N	LAMA3 LAMB2 LAMC3 USH2A	2.51e-07	16	66	4	IPR008211
Domain	LAMININ_NTER	LAMA3 LAMB2 LAMC3 USH2A	2.51e-07	16	66	4	PS51117
Domain	Laminin_N	LAMA3 LAMB2 LAMC3 USH2A	2.51e-07	16	66	4	PF00055
Domain	LamNT	LAMA3 LAMB2 LAMC3 USH2A	2.51e-07	16	66	4	SM00136
Domain	EGF_1	MEGF6 MEGF8 LAMA3 LAMB2 LAMC3 USH2A ITGB8 STAB1	3.14e-06	255	66	8	PS00022
Domain	Growth_fac_rcpt_	MEGF6 MEGF8 LAMA3 LAMB2 LAMC3 STAB1	1.85e-05	156	66	6	IPR009030
Domain	EGF	MEGF6 MEGF8 LAMA3 LAMB2 LAMC3 ITGB8 STAB1	1.89e-05	235	66	7	SM00181
Domain	EGF-like_CS	MEGF6 MEGF8 LAMA3 LAMB2 LAMC3 ITGB8 STAB1	3.70e-05	261	66	7	IPR013032
Domain	EGF_2	MEGF6 MEGF8 LAMA3 LAMB2 LAMC3 ITGB8 STAB1	4.08e-05	265	66	7	PS01186
Domain	EGF-like_dom	MEGF6 MEGF8 LAMA3 LAMB2 LAMC3 STAB1	2.46e-04	249	66	6	IPR000742
Domain	LAMININ_IVA	LAMA3 LAMC3	3.40e-04	8	66	2	PS51115
Domain	Laminin_B	LAMA3 LAMC3	3.40e-04	8	66	2	PF00052
Domain	LamB	LAMA3 LAMC3	3.40e-04	8	66	2	SM00281
Domain	Laminin_IV	LAMA3 LAMC3	3.40e-04	8	66	2	IPR000034
Domain	Integin_beta_N	MEGF8 ITGB8	4.36e-04	9	66	2	IPR033760
Domain	PSI_integrin	MEGF8 ITGB8	4.36e-04	9	66	2	PF17205
Domain	-	BHLHE22 ID4 FIGLA SIM1	5.99e-04	109	66	4	4.10.280.10
Domain	HLH	BHLHE22 ID4 FIGLA SIM1	6.41e-04	111	66	4	PF00010
Domain	-	TPP1 PCSK7	6.63e-04	11	66	2	3.40.50.200
Domain	Peptidase_S8/S53_dom	TPP1 PCSK7	6.63e-04	11	66	2	IPR000209
Domain	Peptidase_S8	TPP1 PCSK7	6.63e-04	11	66	2	PF00082
Domain	HLH	BHLHE22 ID4 FIGLA SIM1	7.57e-04	116	66	4	SM00353
Domain	BHLH	BHLHE22 ID4 FIGLA SIM1	7.81e-04	117	66	4	PS50888
Domain	EGF_3	MEGF8 STAB1	7.93e-04	12	66	2	PF12947
Domain	EGF_dom	MEGF8 STAB1	7.93e-04	12	66	2	IPR024731
Domain	bHLH_dom	BHLHE22 ID4 FIGLA SIM1	8.07e-04	118	66	4	IPR011598
Domain	EGF_extracell	MEGF6 ITGB8 STAB1	1.25e-03	60	66	3	IPR013111
Domain	EGF_2	MEGF6 ITGB8 STAB1	1.25e-03	60	66	3	PF07974
Domain	Propept_inh	TPP1 PCSK7	1.62e-03	17	66	2	IPR009020
Domain	Kelch_1	KLHL1 MEGF8 KBTBD12	1.95e-03	70	66	3	PF01344
Domain	Kelch_1	KLHL1 MEGF8 KBTBD12	1.95e-03	70	66	3	IPR006652
Domain	SRCR	SSC4D DMBT1	2.47e-03	21	66	2	PF00530
Domain	SR	SSC4D DMBT1	3.50e-03	25	66	2	SM00202
Domain	-	SSC4D DMBT1	3.50e-03	25	66	2	3.10.250.10
Domain	SRCR_1	SSC4D DMBT1	3.78e-03	26	66	2	PS00420
Domain	SRCR_2	SSC4D DMBT1	3.78e-03	26	66	2	PS50287
Domain	SRCR-like_dom	SSC4D DMBT1	3.78e-03	26	66	2	IPR017448
Domain	SRCR	SSC4D DMBT1	4.08e-03	27	66	2	IPR001190
Domain	FN3	CSF2RA ABI3BP PTPRZ1 USH2A	4.16e-03	185	66	4	SM00060
Domain	Galactose-bd-like	PCSK7 LAMB2 LAMC3	4.49e-03	94	66	3	IPR008979
Domain	FN3	CSF2RA ABI3BP PTPRZ1 USH2A	5.39e-03	199	66	4	PS50853
Domain	FN3_dom	CSF2RA ABI3BP PTPRZ1 USH2A	6.39e-03	209	66	4	IPR003961
Domain	LAM_G_DOMAIN	LAMA3 USH2A	7.97e-03	38	66	2	PS50025
Domain	-	FCRL3 CSF2RA ABI3BP PDGFRA PTPRZ1 ICAM5 USH2A	8.74e-03	663	66	7	2.60.40.10
Domain	Laminin_G_2	LAMA3 USH2A	8.80e-03	40	66	2	PF02210
Domain	EGF_CA	MEGF6 MEGF8 STAB1	9.23e-03	122	66	3	SM00179
Domain	EGF-like_Ca-bd_dom	MEGF6 MEGF8 STAB1	9.64e-03	124	66	3	IPR001881
Domain	-	ZNF250 SCRT2 HIVEP1 ZBTB32 ZNF550 ZNF516 ZNF304	9.89e-03	679	66	7	3.30.160.60
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	LAMA3 LAMB2 LAMC3	1.09e-04	30	44	3	M27772
Pathway	REACTOME_LAMININ_INTERACTIONS	LAMA3 LAMB2 LAMC3	1.09e-04	30	44	3	M27216
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	LAMA3 LAMB2 LAMC3 ITGB8	1.33e-04	84	44	4	M7098
Pathway	WP_FOCAL_ADHESION	PDGFRA LAMA3 LAMB2 LAMC3 ITGB8	2.78e-04	187	44	5	MM15913
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	LAMA3 LAMB2 LAMC3	2.78e-04	41	44	3	M27778
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	CAPN12 ICAM5 LAMA3 LAMB2 LAMC3 ITGB8	3.16e-04	300	44	6	M610
Pathway	WP_FOCAL_ADHESION	PDGFRA LAMA3 LAMB2 LAMC3 ITGB8	3.70e-04	199	44	5	M39402
Pathway	KEGG_FOCAL_ADHESION	PDGFRA LAMA3 LAMB2 LAMC3 ITGB8	3.70e-04	199	44	5	M7253
Pathway	PID_A6B1_A6B4_INTEGRIN_PATHWAY	LAMA3 LAMB2 LAMC3	3.92e-04	46	44	3	M239
Pathway	PID_INTEGRIN4_PATHWAY	LAMA3 LAMB2	5.14e-04	11	44	2	M158
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	LAMA3 LAMB2 LAMC3	8.16e-04	59	44	3	M27218
Pubmed	A new nomenclature for the laminins.	LAMA3 LAMB2 LAMC3	2.38e-07	7	67	3	7921537
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMA3 LAMB2 LAMC3	1.12e-06	11	67	3	21524702
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	GRIP1 SSC4D HIVEP1 MEGF6 MEGF8 LAMB2 MTUS2 OPLAH STAB1	1.27e-06	560	67	9	21653829
Pubmed	Basement membrane composition in the early mouse embryo day 7.	LAMA3 LAMB2 LAMC3	3.06e-06	15	67	3	15895400
Pubmed	Laminins containing the β2 and γ3 chains regulate astrocyte migration and angiogenesis in the retina.	LAMB2 LAMC3	3.66e-06	2	67	2	23571221
Pubmed	Defective formation of the inner limiting membrane in laminin beta2- and gamma3-null mice produces retinal dysplasia.	LAMB2 LAMC3	3.66e-06	2	67	2	19907020
Pubmed	β2 and γ3 laminins are critical cortical basement membrane components: ablation of Lamb2 and Lamc3 genes disrupts cortical lamination and produces dysplasia.	LAMB2 LAMC3	3.66e-06	2	67	2	22961762
Pubmed	Three SNPs of FCRL3 and one SNP of MTMR3 are associated with immunoglobulin A nephropathy risk.	FCRL3 MTMR3	3.66e-06	2	67	2	31780315
Pubmed	Cellular and axonal constituents of neocortical molecular layer heterotopia.	LAMB2 LAMC3	3.66e-06	2	67	2	25247689
Pubmed	Laminin-Dependent Interaction between Astrocytes and Microglia: A Role in Retinal Angiogenesis.	LAMB2 LAMC3	3.66e-06	2	67	2	28697326
Pubmed	Laminin deficits induce alterations in the development of dopaminergic neurons in the mouse retina.	LAMB2 LAMC3	3.66e-06	2	67	2	17711601
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMA3 LAMB2 LAMC3	3.76e-06	16	67	3	17601529
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMA3 LAMB2 LAMC3	5.46e-06	18	67	3	11311202
Pubmed	Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.	LAMA3 LAMB2 LAMC3	7.61e-06	20	67	3	22911573
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MEGF6 MEGF8 ADAMTS7 ZNF516 MTMR3 LAMB2 LAMC3 TANC1 ELL GAREM1 HR	7.99e-06	1105	67	11	35748872
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	ABI3BP LAMA3 LAMB2 LAMC3	1.69e-05	79	67	4	18757743
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	LAMA3 LAMB2 LAMC3	1.72e-05	26	67	3	24742657
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	ABI3BP LAMA3 LAMB2 DMBT1 COLQ	1.83e-05	167	67	5	22159717
Pubmed	Human colonic cancer cells synthesize and adhere to laminin-5. Their adhesion to laminin-5 involves multiple receptors among which is integrin alpha2beta1.	LAMB2 LAMC3	2.19e-05	4	67	2	9645947
Pubmed	Genetic deletion of laminin isoforms β2 and γ3 induces a reduction in Kir4.1 and aquaporin-4 expression and function in the retina.	LAMB2 LAMC3	2.19e-05	4	67	2	21283711
Pubmed	Developmental expression of nicein adhesion protein (laminin-5) subunits suggests multiple morphogenic roles.	LAMA3 LAMB2	2.19e-05	4	67	2	8081888
Pubmed	Identification of low-dose radiation-induced exosomal circ-METRN and miR-4709-3p/GRB14/PDGFRα pathway as a key regulatory mechanism in Glioblastoma progression and radioresistance: Functional validation and clinical theranostic significance.	PDGFRA GRB14	2.19e-05	4	67	2	33867829
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	GRIP1 LAMA3 LAMB2	2.41e-05	29	67	3	22613833
Pubmed	Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis.	LAMB2 LAMC3	3.64e-05	5	67	2	16581764
Pubmed	Regulation of melanoma cell migration and invasion by laminin-5 and alpha3beta1 integrin (VLA-3).	LAMB2 LAMC3	3.64e-05	5	67	2	11964076
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	GRIP1 MIB1 TANC1 MCCC2 SIK3 NMT1 PDZRN3 ELL RGS12	3.69e-05	853	67	9	28718761
Pubmed	Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.	BHLHE22 ID4 FIGLA SIM1	3.96e-05	98	67	4	18557763
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	GRIP1 AARS1 HIVEP1 MEGF8 PDGFRA NUB1 TANC1 SIK3 RGS12	3.96e-05	861	67	9	36931259
Pubmed	Cloning and characterization of GRB14, a novel member of the GRB7 gene family.	PDGFRA GRB14	5.46e-05	6	67	2	8647858
Pubmed	Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio.	GRB14 STAB1	5.46e-05	6	67	2	23670221
Pubmed	Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor.	LAMA3 LAMB2	7.63e-05	7	67	2	9004048
Pubmed	Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.	PCSK7 SIK3	7.63e-05	7	67	2	21149283
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	HIVEP1 MEGF6 MEGF8 LAMB2	8.18e-05	118	67	4	21078624
Pubmed	Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.	MEGF6 MEGF8	1.30e-04	9	67	2	9693030
Pubmed	Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.	LAMA3 LAMB2	1.63e-04	10	67	2	9034910
Pubmed	Proteomic and functional evidence for a P2X7 receptor signalling complex.	PTPRZ1 LAMA3	1.99e-04	11	67	2	11707406
Pubmed	Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.	LAMB2 LAMC3	1.99e-04	11	67	2	23472759
Pubmed	Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning.	LAMB2 LAMC3	2.38e-04	12	67	2	26794322
Pubmed	Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.	LAMA3 LAMB2	2.38e-04	12	67	2	9396756
Pubmed	A human MAP kinase interactome.	HIVEP1 ABI3BP LAMA3 LAMB2 SIK3 GAREM1	3.51e-04	486	67	6	20936779
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	MEGF6 LAMA3 LAMB2 DMBT1	3.71e-04	175	67	4	28071719
Pubmed	A global genomic transcriptional code associated with CNS-expressed genes.	KLHL1 BHLHE22 ID4 GRB14 USH2A	3.76e-04	318	67	5	16919269
Pubmed	Neurogenin3 participates in gliogenesis in the developing vertebrate spinal cord.	PDGFRA SIM1	3.78e-04	15	67	2	12490199
Pubmed	Mash1 and Math3 are required for development of branchiomotor neurons and maintenance of neural progenitors.	PDGFRA SIM1	3.78e-04	15	67	2	15976074
Pubmed	Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain.	PDGFRA SIM1	4.31e-04	16	67	2	15629702
Pubmed	Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.	GRIP1 LAMA3	4.31e-04	16	67	2	16880404
Pubmed	The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination.	PDGFRA ID4	5.48e-04	18	67	2	19838178
Pubmed	Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding.	PDGFRA BHLHE22	6.79e-04	20	67	2	34407390
Pubmed	PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.	PDGFRA LAMA3	7.50e-04	21	67	2	27856617
Pubmed	Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.	PDGFRA SIM1	8.24e-04	22	67	2	11955448
Pubmed	Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity.	BHLHE22 SIM1	8.24e-04	22	67	2	38160393
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ASXL1 MEGF6 SIK3 STAB1	9.50e-04	225	67	4	12168954
Pubmed	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	GRB14 STAB1	9.82e-04	24	67	2	20935629
Pubmed	MicroRNAs establish robustness and adaptability of a critical gene network to regulate progenitor fate decisions during cortical neurogenesis.	BHLHE22 PDZRN3	9.82e-04	24	67	2	24931612
Pubmed	Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation.	PDGFRA ID4	1.07e-03	25	67	2	32266943
Pubmed	The structural role of radial glial endfeet in confining spinal motor neuron somata is controlled by the Reelin and Notch pathways.	MIB1 SIM1	1.15e-03	26	67	2	23988635
Pubmed	The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/β-catenin signaling.	PDGFRA ID4	1.15e-03	26	67	2	25810530
Pubmed	Congenital Myasthenic Syndromes Overview	LAMB2 COLQ	1.15e-03	26	67	2	20301347
Pubmed	TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1.	AARS1 MIB1 SBSN	1.52e-03	117	67	3	36898370
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	AARS1 TPP1 TANC1 SIK3 NMT1 HR	1.58e-03	650	67	6	38777146
Pubmed	TBX1 is required for normal stria vascularis and semicircular canal development.	AARS1 STAB1	1.64e-03	31	67	2	31550482
Pubmed	Specific functions for ERK/MAPK signaling during PNS development.	PDGFRA ID4	1.64e-03	31	67	2	21220101
Pubmed	Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination.	PDGFRA ID4	1.75e-03	32	67	2	26928066
Pubmed	Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor.	PDGFRA SIM1	1.75e-03	32	67	2	27806288
Pubmed	Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.	PDGFRA ID4	1.86e-03	33	67	2	27416896
Pubmed	Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.	BHLHE22 GRB14 SIM1	1.88e-03	126	67	3	16284245
Interaction	SLURP1 interactions	MEGF8 ADAMTS7 ICAM5 LAMA3 LAMB2 SIK3	7.65e-06	144	66	6	int:SLURP1
GeneFamily	Laminin subunits	LAMA3 LAMB2 LAMC3	3.34e-06	12	46	3	626
GeneFamily	Basic helix-loop-helix proteins	BHLHE22 ID4 FIGLA SIM1	1.74e-04	110	46	4	420
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF250 SCRT2 HIVEP1 ZBTB32 ZNF550 ZNF516 ZNF304	2.10e-03	718	46	7	28
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	SSC4D STAB1	2.13e-03	27	46	2	1253
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	ZBTB32 KLHL1 KBTBD12	4.79e-03	134	46	3	861
GeneFamily	PDZ domain containing	GRIP1 PDZRN3 RGS12	6.79e-03	152	46	3	1220
GeneFamily	Fibronectin type III domain containing	ABI3BP PTPRZ1 USH2A	7.81e-03	160	46	3	555
Coexpression	NABA_BASEMENT_MEMBRANES	LAMA3 LAMB2 LAMC3 COLQ USH2A	5.76e-08	40	67	5	M5887
Coexpression	NABA_ECM_GLYCOPROTEINS	ABI3BP LAMA3 LAMB2 LAMC3 DMBT1 COLQ USH2A	6.99e-07	196	67	7	M3008
Coexpression	NABA_CORE_MATRISOME	ABI3BP LAMA3 LAMB2 LAMC3 DMBT1 COLQ USH2A	6.59e-06	275	67	7	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	ABI3BP LAMA3 LAMB2 LAMC3 DMBT1 COLQ	9.55e-06	191	67	6	MM17059
Coexpression	VERHAAK_GLIOBLASTOMA_CLASSICAL	MEGF8 LAMB2 ITGB8 RGS12 ZNF304	5.84e-05	161	67	5	M2121
Coexpression	NABA_CORE_MATRISOME	ABI3BP LAMA3 LAMB2 LAMC3 DMBT1 COLQ	6.66e-05	270	67	6	MM17057
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SSC4D ABI3BP GRB14 SIM1 ITGB8 RGS12	4.22e-07	190	67	6	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADRA1D BHLHE22 TANC1 PDZRN3 HR	4.73e-06	163	67	5	1e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADRA1D BHLHE22 TANC1 PDZRN3 HR	4.73e-06	163	67	5	431221a41d396b09170476179590eaf8a55266d8
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MEGF6 ABI3BP PDGFRA PTPRZ1 HR	6.50e-06	174	67	5	9c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MEGF6 ABI3BP PDGFRA PTPRZ1 HR	6.50e-06	174	67	5	bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HIVEP1 PCSK7 LAMB2 MCCC2 SIK3	6.68e-06	175	67	5	dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SSC4D ABI3BP GRB14 ITGB8 RGS12	7.45e-06	179	67	5	55bc69f107fc710db7617c428575792adfdbbcc1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADRA1D PTPRZ1 LAMA3 LAMC3 RGS12	7.87e-06	181	67	5	35bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABI3BP PTPRZ1 LAMA3 LAMC3 RGS12	8.52e-06	184	67	5	32473dbdb2de66391157c5814ef34e790806e4f2
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRZ1 BHLHE22 LAMA3 TANC1 USH2A	8.75e-06	185	67	5	10da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	AARS1 ZBTB32 MIB1 PDP2 STAB1	9.21e-06	187	67	5	1eed2c1a05e80a7c8f639437c117afe0c18dfb0c
ToppCell	facs-Heart-Unknown\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLIN5 GRB14 KBTBD12 MTUS2 PM20D2	9.21e-06	187	67	5	362e56426a568423a81e8a30e3ecf99b76135843
ToppCell	facs-Heart-Unknown-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLIN5 GRB14 KBTBD12 MTUS2 PM20D2	9.21e-06	187	67	5	c004567767b89f3d89f5c7b28d952f3445957e1e
ToppCell	-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	ABI3BP PDGFRA BHLHE22 LAMC3 PDZRN3	9.45e-06	188	67	5	038f48e8daaeb72716e975d22a6b004a90654960
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABI3BP PTPRZ1 LAMA3 LAMC3 RGS12	1.05e-05	192	67	5	025fac36b862f9ca7f96fb4a1946c44ba7cbc382
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP LAMA3 SIM1 ITGB8 GAREM1	1.10e-05	194	67	5	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GRIP1 GRB14 SIM1 ITGB8 GAREM1	1.10e-05	194	67	5	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	NS-moderate-d_07-13\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FCRL3 ZBTB32 ITGB8 SBSN STAB1	1.13e-05	195	67	5	088209505a68519ec89f50f0576096da6966bf17
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ABI3BP PDGFRA ID4 LAMB2 PDZRN3	1.24e-05	199	67	5	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Mesothelial-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	ABI3BP PDGFRA ADAMTS7 GRB14 PDZRN3	1.24e-05	199	67	5	60a653100aff31f7f96796ff2ec634798bfb4b0d
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GRIP1 PTPRZ1 PLIN5 GRB14 DMBT1	1.27e-05	200	67	5	7c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Scn4b_(Globus_Pallidus_Externus_(GP),_"Prototypical")--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ADRA1D FIGLA COLQ	6.25e-05	51	67	3	74d7932d0e7363c00117890747980b4b04ff4524
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Scn4b_(Globus_Pallidus_Externus_(GP),_"Prototypical")-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ADRA1D FIGLA COLQ	6.25e-05	51	67	3	88597bef58fe807b65da34925e863e7fbe3a7e3e
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Scn4b_(Globus_Pallidus_Externus_(GP),_"Prototypical")\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ADRA1D FIGLA COLQ	6.25e-05	51	67	3	91e17b1a85e2b5c507c64f39f322a5a9b7bf30bd
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PDGFRA PTPRZ1 ID4 RGS12	7.53e-05	149	67	4	10ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1D GRB14 KBTBD12 USH2A	7.53e-05	149	67	4	cc911b454fe4e4b489885b9920baa7eb01a027ba
ToppCell	3'_v3-blood-Lymphocytic_T_CD8-Trm_gut_CD8\|blood / Manually curated celltypes from each tissue	GRIP1 AARS1 CFAP54 ZBTB32	8.13e-05	152	67	4	1fea735321da6db6d2cd3f83d2f7fac72d44904d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PTPRZ1 ID4 DMBT1 RGS12	8.77e-05	155	67	4	cba6f3f7742b4d5d54ad0a0ac0dd4016e73fe658
ToppCell	Severe-Lymphoid-NK-Proliferating_T\|Severe / Condition, Lineage, Cell class and cell subclass	ZBTB32 MEGF6 PDP2 IFT80	9.92e-05	160	67	4	cb2276d9bd78508644420e9580d3c17b914224cb
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PTPRZ1 LAMA3 ID4 RGS12	1.02e-04	161	67	4	3b5d7a3dab479c6959a428f3954dedd989900276
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PDGFRA PTPRZ1 LAMA3 RGS12	1.02e-04	161	67	4	be77e99faf653480c166305df3a4e93db76f0dcb
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ADRA1D ICAM5 TANC1 GAREM1	1.20e-04	168	67	4	6db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRIP1 LAMA3 GRB14 KBTBD12	1.22e-04	169	67	4	4b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCell	droplet-Kidney-nan-18m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ID4 MCCC2 USH2A ITGB8	1.22e-04	169	67	4	f00741203efa0b948db7223ee8c19bdd0918258a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRIP1 LAMA3 GRB14 KBTBD12	1.22e-04	169	67	4	a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL1 HHIPL2 ITGB8 RGS12	1.25e-04	170	67	4	6af7dee9b8298d4499e05a82cf9cdfe3bd81d384
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L6_THEMIS_C6orf48\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL1 HHIPL2 ITGB8 RGS12	1.28e-04	171	67	4	75279ca22f5dd6cfee11c83f3a7b5f828cdec1c6
ToppCell	Influenza_Severe-B_intermediate\|World / Disease group and Cell class	FCRL3 ZBTB32 KBTBD12 MTUS2	1.28e-04	171	67	4	4d33e1dc1efc423dbdd5f4cca6d6440a68add8d0
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L6_THEMIS_C6orf48\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL1 HHIPL2 ITGB8 RGS12	1.34e-04	173	67	4	8bc916ccf687df0341ec1d77d62844bf890cad47
ToppCell	TCGA-Brain-Primary_Tumor\|TCGA-Brain / Sample_Type by Project: Shred V9	PTPRZ1 ID4 PDP2 MCCC2	1.34e-04	173	67	4	f6ba22661e67c17d49d1058d4170ba8f36bf47f0
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL1 HHIPL2 ITGB8 RGS12	1.37e-04	174	67	4	0df738309b7b6e77675ea74e7a87e66601b0073d
ToppCell	Influenza_Severe-B_intermediate\|Influenza_Severe / Disease group and Cell class	FCRL3 ZBTB32 KBTBD12 MTUS2	1.37e-04	174	67	4	4276bdaac53aebd3084323a90ecde572d3177446
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRZ1 LAMA3 LAMC3 RGS12	1.40e-04	175	67	4	9d09636a103daa8f622c3dbfd1f1536aaec3b6bb
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_GRIP2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIP1 ADRA1D LAMA3 RGS12	1.40e-04	175	67	4	0c648e7f67ffbe3b476a2ca77d246554f8cd1882
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRZ1 LAMA3 LAMC3 RGS12	1.40e-04	175	67	4	5a9160a9d05e01d945e77fd81bb0bd87139545cd
ToppCell	COVID-19-kidney-CD-IC-A\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GRIP1 GRB14 KBTBD12 SIM1	1.43e-04	176	67	4	45028197364c64e93e3ffe86aff773d47a477d49
ToppCell	metastatic_Brain-Endothelial_cells-Lymphatic_ECs\|Endothelial_cells / Location, Cell class and cell subclass	CSF2RA PLIN5 ITGB8 PM20D2	1.43e-04	176	67	4	42541dfe20eb29625d47c0bb79bf3c21a2460340
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL1 HHIPL2 ITGB8 RGS12	1.43e-04	176	67	4	de746cdf2c777eec88cb03863e128e97ad6e8fb0
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRZ1 BHLHE22 GRB14 PDZRN3	1.46e-04	177	67	4	f902600c639087664316b3cf30cab243bc3d1c5c
ToppCell	facs-Heart-RV-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLIN5 GRB14 COLQ MTUS2	1.46e-04	177	67	4	692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL1 HHIPL2 ITGB8 RGS12	1.46e-04	177	67	4	64fbf799e7b0c4003b2f486cc41b0f7e7c11ea0c
ToppCell	facs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLIN5 GRB14 COLQ MTUS2	1.46e-04	177	67	4	c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MEGF6 ABI3BP ID4 SBSN	1.49e-04	178	67	4	a107dd98a07086ed0429116095ecda60c9dbef1e
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MEGF6 ABI3BP ID4 SBSN	1.49e-04	178	67	4	bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MEGF6 ABI3BP ID4 SBSN	1.49e-04	178	67	4	c413861148129be1ee94f2ceb5999840217eebe5
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-cDC2\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GRIP1 CSF2RA MTUS2 RGS12	1.49e-04	178	67	4	32120936a524c38e621bd2fca17524fef74422e0
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL1 HHIPL2 ITGB8 RGS12	1.49e-04	178	67	4	a62137d7f5fac16619f8a02844cdb0be7a794bf2
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRZ1 BHLHE22 GRB14 PDZRN3	1.53e-04	179	67	4	8766a5a066091879f521acfc612abf563ff78808
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac\|lymph-node_spleen / Manually curated celltypes from each tissue	CSF2RA PDGFRA OPLAH STAB1	1.56e-04	180	67	4	4eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF250 BHLHE22 LAMC3 STAB1	1.56e-04	180	67	4	79c5725f02e038d0187f4a1e1591f2492538aa57
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL1 GRB14 LAMC3 RGS12	1.56e-04	180	67	4	b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL1 HHIPL2 ITGB8 RGS12	1.56e-04	180	67	4	7a9aa96fb8035020640cc7d3df0c41c730516c6f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_DSEL\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRZ1 LAMA3 LAMC3 RGS12	1.59e-04	181	67	4	70eff83dd85691e977972c660731394d2fcf5cdf
ToppCell	VE-matDC\|VE / Condition, Cell_class and T cell subcluster	CSF2RA ICAM5 BHLHE22 FIGLA	1.59e-04	181	67	4	982fd96ef75bc9ab2c2f4970c01b76ba7a164871
ToppCell	VE-matDC-\|VE / Condition, Cell_class and T cell subcluster	CSF2RA ICAM5 BHLHE22 FIGLA	1.59e-04	181	67	4	6252184ef098b911df50be4fe1b5565849a5b6b8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRZ1 LAMA3 LAMC3 RGS12	1.59e-04	181	67	4	7846c7b33d1b89364c5a704edaa86520db731c89
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDGFRA LAMA3 LAMC3 RGS12	1.63e-04	182	67	4	3d7a8d2ee2137b098248597058974ef5ae09c19e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 ABI3BP PDZRN3 ITGB8	1.63e-04	182	67	4	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MEGF6 ABI3BP ID4 SBSN	1.63e-04	182	67	4	9966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCell	Adult-Epithelial-basal_cell\|Adult / Lineage, Cell type, age group and donor	GRIP1 PTPRZ1 HR PM20D2	1.66e-04	183	67	4	00a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HIVEP1 CSF2RA ICAM5 NUB1	1.66e-04	183	67	4	9ca4954faaba50466c35121d6765895e955178aa
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN12 LAMB2 LAMC3 PDZRN3	1.70e-04	184	67	4	94748f63947db79a6b4540e3090a63689fdd9452
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP54 ABI3BP PTPRZ1 ID4	1.70e-04	184	67	4	6b0c110d8930df99043c3b99cf4d873985126960
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP54 ABI3BP PTPRZ1 ID4	1.70e-04	184	67	4	35928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN12 LAMB2 LAMC3 PDZRN3	1.70e-04	184	67	4	819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GRIP1 MEGF6 ID4 SBSN	1.70e-04	184	67	4	607b55022de21ddb6a2d75e085df76df7abf6624
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEGF6 PTPRZ1 LAMB2 LAMC3	1.73e-04	185	67	4	f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	ABI3BP PDGFRA PDZRN3 ITGB8	1.73e-04	185	67	4	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIP1 ADRA1D LAMA3 RGS12	1.73e-04	185	67	4	4c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 ABI3BP PDZRN3 ITGB8	1.77e-04	186	67	4	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KLHL1 LAMA3 USH2A STAB1	1.77e-04	186	67	4	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIP1 ADRA1D LAMA3 RGS12	1.77e-04	186	67	4	310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCell	facs-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADRA1D BHLHE22 ID4 ITGB8	1.77e-04	186	67	4	26458ff8cad5577de4306cffa0ca69eb26940e0d
ToppCell	facs-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADRA1D BHLHE22 ID4 ITGB8	1.77e-04	186	67	4	a71397efc68d2916ddc373d92cfd07be58033e1c
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GRIP1 PTPRZ1 LAMA3 GRB14	1.77e-04	186	67	4	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	AARS1 ZBTB32 MIB1 STAB1	1.77e-04	186	67	4	74eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GRIP1 PTPRZ1 LAMA3 GRB14	1.81e-04	187	67	4	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	facs-Heart-Unknown-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLIN5 KBTBD12 MTUS2 PM20D2	1.81e-04	187	67	4	0ffb988e0da2c7205c3515eca8e9851739bff5c5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA3 SIM1 MTUS2 GAREM1	1.81e-04	187	67	4	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GRIP1 GRB14 SIM1 ITGB8	1.81e-04	187	67	4	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRB14 SIM1 ITGB8 RGS12	1.81e-04	187	67	4	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABI3BP PTPRZ1 LAMA3 RGS12	1.84e-04	188	67	4	6ee3f8f94ea7bdf652c9575fc65bff08070093a4
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABI3BP PTPRZ1 LAMA3 RGS12	1.84e-04	188	67	4	c66fccdfe68760b8c3efca77e3c25966dc9a8a5f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIP1 ADRA1D LAMA3 RGS12	1.84e-04	188	67	4	0501a8aa850bd2e347020abd1cac4d8075738189
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GRIP1 GRB14 SIM1 GAREM1	1.84e-04	188	67	4	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	AARS1 PLIN5 DMBT1 GAREM1	1.84e-04	188	67	4	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GRIP1 PTPRZ1 LAMA3 GRB14	1.84e-04	188	67	4	beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRIP1 SSC4D SIM1 GAREM1	1.84e-04	188	67	4	4154f4787483c7e076e87a187733a9f666742c3d
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	GRIP1 ID4 TANC1 PDZRN3	1.84e-04	188	67	4	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP BHLHE22 GRB14 OPLAH	1.88e-04	189	67	4	1db5dd1ef2a65251af2d5696622d1dd9c4ae2b55
Drug	AC1L1G72	LAMA3 LAMB2 LAMC3	3.95e-06	11	67	3	CID000003553
Disease	soluble transferrin receptor measurement, iron biomarker measurement	PCSK7 SIK3	4.91e-05	5	66	2	EFO_0004460, EFO_0004461
Disease	helping behavior measurement	SCRT2 USH2A	1.37e-04	8	66	2	EFO_0008538
Disease	proprotein convertase subtilisin/kexin type 7 measurement	PCSK7 SIK3	6.56e-04	17	66	2	EFO_0008270
Disease	total cholesterol measurement, high density lipoprotein cholesterol measurement	PCSK7 GRB14 SIK3 COLQ RGS12	7.05e-04	315	66	5	EFO_0004574, EFO_0004612
Disease	Charcot-Marie-Tooth disease (implicated_via_orthology)	AARS1 MTMR3	1.32e-03	24	66	2	DOID:10595 (implicated_via_orthology)
Disease	Myasthenic Syndromes, Congenital	LAMB2 COLQ	1.32e-03	24	66	2	C0751882
Disease	eye colour measurement	DMBT1 SIM1 USH2A ZNF304	1.46e-03	218	66	4	EFO_0009764
Disease	glucose measurement	MEGF8 MTMR3 GRB14 IFT80 NMT1	1.62e-03	380	66	5	EFO_0004468
Disease	creatinine measurement	CAPN12 ADAMTS7 MTMR3 SIM1 FBXL20 ELL RGS12 OPLAH	1.65e-03	995	66	8	EFO_0004518
Disease	proteinuria (implicated_via_orthology)	LAMB2 HR	2.06e-03	30	66	2	DOID:576 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
DCHAGIHGEAFARRA	CFAP54	306	Q96N23
SNDLGHSGRDCEHGE	ELL	401	P55199
HSGRDCEHGEAAAPA	ELL	406	P55199
GGAKAAEGCSNAHLH	BHLHE22	176	Q8NFJ8
AEGCSNAHLHGGASV	BHLHE22	181	Q8NFJ8
HCHREAATTAIGGGG	ASXL1	631	Q8IXJ9
GHSFGIQHDGSGNDC	ADAMTS7	391	Q9UKP4
SDLHHLGVGRGNCEE	MTUS2	366	Q5JR59
THGEQRAGGHCCARA	PDZRN3	151	Q9UPQ7
HAFQCSHRGGELGIS	PBLD	251	P30039
GLRACDGNVDHAATH	NUB1	396	Q9Y5A7
VDDHHGSTGGQTVRC	PDGFRA	421	P16234
GDGHRHEGVEDCDGS	COLQ	406	Q9Y215
RQGDGDCHCKSHVGG	LAMA3	646	Q16787
EGNGNGHEHCSDCEN	NMT1	21	P30419
GGADLHCRKSGVSDH	MCCC2	261	Q9HCC0
AQAAGEGGGHACHSQ	HR	501	O43593
EGGGHACHSQQVRRS	HR	506	O43593
DVENGNHHGTRCAGE	PCSK7	221	Q16549
GSHGGEYECAATNAH	ICAM5	806	Q9UMF0
HGNSEVNLHGCRDLG	GAREM1	396	Q9H706
TCHLRQGGAHCGDDG	MEGF8	871	Q7Z7M0
HGACLSGDQAHRLGC	MEGF8	1896	Q7Z7M0
NRHSECAGVGARDHC	MEGF8	2256	Q7Z7M0
GGVCDGCQHNTAGRH	LAMB2	371	P55268
GHADECNTHTGACLG	LAMB2	881	P55268
GGEHCERCIAGFHGD	LAMB2	901	P55268
VHDEHGGVTAGTFCA	PTPRZ1	2221	P23471
RCLAEHGHSLGGSAA	ID4	26	P47928
DGDRAVHHAAFGDEG	MIB1	496	Q86YT6
HHGNLCAGHGECEAG	ITGB8	556	P26012
DGHGGHACAQAVSER	PDP2	141	Q9P2J9
FCHCSQHLDGGEGVI	CAPN12	691	Q6ZSI9
GACGNGHVVFAHVVE	IFT80	286	Q9P2H3
CDADNGLGAQHSHGV	FCRL3	451	Q96P31
VCGAAQGRGDAHDLA	GRB14	26	Q14449
DGNGVLHHRGFGVAC	ENDOV	126	Q8N8Q3
DGGSGEPAHACRHSV	FIGLA	176	Q6QHK4
GLQESHGRDGTRFCH	HHIPL2	156	Q6UWX4
ASIADRCGALHVGDH	GRIP1	286	Q9Y3R0
HNCGHSEDAGVICSA	DMBT1	321	Q9UGM3
HNCGHSEDAGVICSG	DMBT1	581	Q9UGM3
AHHAAGQAGNEAGRF	SBSN	246	Q6UWP8
DSGTHVGCHLDNLSG	CSF2RA	171	P15509
DFGHKFADRCGHGEN	MTMR3	451	Q13615
VCGGFHGADRHEVIS	KBTBD12	556	Q3ZCT8
DVDECRTHNGGCQHR	MEGF6	161	O75095
EHFRGGGGVCDDCEH	USH2A	596	O75445
SGNQICCAGRLHDGH	USH2A	3276	O75445
GAQAGGGHRHACAEC	SCRT2	146	Q9NQ03
SAHVLACFGGAGGQH	OPLAH	481	O14841
DGIRHLGNGACAHDQ	FBXL20	341	Q96IG2
HFHTQACEGGRCEAG	SIM1	461	P81133
GENEECGASLGGHEH	SIK3	1266	Q9Y2K2
GQCALVHSALRGHGD	TANC1	1001	Q9C0D5
GHACGHNLIAEVGAA	PM20D2	121	Q8IYS1
IHCRGAATGADGAHG	ADRA1D	306	P25100
EASGHERGCHQVNAC	C10orf143	31	A0A1B0GUT2
DCQRGQGLHALSGHT	WDR47	741	O94967
GRGHEVDGDKATCHT	ZNF516	21	Q92618
ECGECGRAFNQHGHL	ZNF250	536	P15622
GDHADDALHANGGLC	RGS12	916	O14924
RGRSHDAHSGGCSAD	RBMXL3	556	Q8N7X1
EFCGGTHLRNSSHAG	AARS1	721	P49588
HNCGHHEDAGALCAG	SSC4D	276	Q8WTU2
HNCGHHEDAGALCAG	SSC4D	431	Q8WTU2
VADLCQDGHGGCSEH	STAB1	2091	Q9NY15
QDGHGGCSEHANCSQ	STAB1	2096	Q9NY15
GLSHATCAGDRAQVH	ZNF550	76	Q7Z398
SDQGHTGALATCAGH	ZBTB32	336	Q9Y2Y4
AHTGERAHECNSFGG	ZNF304	636	Q9HCX3
EGRGRVAHAHACVDE	PLIN5	346	Q00G26
DHDCSGEGHPTSRAG	ZFAND2B	131	Q8WV99
GDQRGHGEDHCQFVD	ABI3BP	996	Q7Z7G0
GQSLDESHQGCHAAG	HIVEP1	916	P15822
HGAGLFDVTRGCHES	TPP1	511	O14773
AVGGHDAPASNHCSR	KLHL1	651	Q9NR64
GAAGAGAHCQRCDAA	LAMC3	66	Q9Y6N6