Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	natriuretic peptide receptor activity	NPR1 NPR2	2.57e-05	3	59	2	GO:0016941
GeneOntologyMolecularFunction	hormone activity	LHB CGB1 CGB2 CGB3 CGB7	4.90e-05	135	59	5	GO:0005179
GeneOntologyMolecularFunction	guanylate cyclase activity	NPR1 NPR2	3.80e-04	10	59	2	GO:0004383
GeneOntologyMolecularFunction	signaling receptor regulator activity	JAG2 LHB CGB1 CGB2 CGB3 CGB7 CCL23 FST	4.34e-04	616	59	8	GO:0030545
GeneOntologyMolecularFunction	receptor ligand activity	JAG2 LHB CGB1 CGB2 CGB3 CGB7 CCL23	1.11e-03	547	59	7	GO:0048018
GeneOntologyMolecularFunction	signaling receptor activator activity	JAG2 LHB CGB1 CGB2 CGB3 CGB7 CCL23	1.19e-03	554	59	7	GO:0030546
GeneOntologyMolecularFunction	adenylate cyclase activity	NPR1 NPR2	1.27e-03	18	59	2	GO:0004016
GeneOntologyMolecularFunction	cyclase activity	NPR1 NPR2	2.27e-03	24	59	2	GO:0009975
GeneOntologyMolecularFunction	phosphorus-oxygen lyase activity	NPR1 NPR2	2.46e-03	25	59	2	GO:0016849
GeneOntologyBiologicalProcess	luteinizing hormone signaling pathway involved in ovarian follicle development	LHB CGB1 CGB2 CGB7	3.01e-10	5	59	4	GO:0035471
GeneOntologyBiologicalProcess	luteinizing hormone signaling pathway	LHB CGB1 CGB2 CGB7	2.10e-09	7	59	4	GO:0042700
GeneOntologyBiologicalProcess	female gonad development	LHB NPR2 CGB1 CGB2 CGB7 FST	2.71e-06	138	59	6	GO:0008585
GeneOntologyBiologicalProcess	development of primary female sexual characteristics	LHB NPR2 CGB1 CGB2 CGB7 FST	3.20e-06	142	59	6	GO:0046545
GeneOntologyBiologicalProcess	ovarian follicle development	LHB NPR2 CGB1 CGB2 CGB7	4.97e-06	87	59	5	GO:0001541
GeneOntologyBiologicalProcess	female sex differentiation	LHB NPR2 CGB1 CGB2 CGB7 FST	5.71e-06	157	59	6	GO:0046660
GeneOntologyBiologicalProcess	molting cycle	KRTAP4-5 KRTAP4-8 KRTAP4-11 KRTAP4-9 FST	6.94e-05	150	59	5	GO:0042303
GeneOntologyBiologicalProcess	hair cycle	KRTAP4-5 KRTAP4-8 KRTAP4-11 KRTAP4-9 FST	6.94e-05	150	59	5	GO:0042633
GeneOntologyBiologicalProcess	gonad development	LHB NPR2 CGB1 CGB2 CGB7 FST	1.84e-04	292	59	6	GO:0008406
GeneOntologyBiologicalProcess	development of primary sexual characteristics	LHB NPR2 CGB1 CGB2 CGB7 FST	2.01e-04	297	59	6	GO:0045137
GeneOntologyBiologicalProcess	positive regulation of cGMP-mediated signaling	NPR1 NPR2	2.86e-04	9	59	2	GO:0010753
GeneOntologyBiologicalProcess	sex differentiation	LHB NPR2 CGB1 CGB2 CGB7 FST	4.98e-04	352	59	6	GO:0007548
GeneOntologyBiologicalProcess	cGMP biosynthetic process	NPR1 NPR2	5.21e-04	12	59	2	GO:0006182
GeneOntologyBiologicalProcess	receptor guanylyl cyclase signaling pathway	NPR1 NPR2	5.21e-04	12	59	2	GO:0007168
GeneOntologyBiologicalProcess	reproductive structure development	LHB NPR2 CGB1 CGB2 CGB7 FST	7.75e-04	383	59	6	GO:0048608
GeneOntologyBiologicalProcess	regulation of cGMP-mediated signaling	NPR1 NPR2	8.25e-04	15	59	2	GO:0010752
GeneOntologyBiologicalProcess	reproductive system development	LHB NPR2 CGB1 CGB2 CGB7 FST	8.29e-04	388	59	6	GO:0061458
GeneOntologyCellularComponent	keratin filament	KRTAP9-7 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP4-6 KRTAP4-9 KRTAP11-1 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	1.44e-22	97	60	15	GO:0045095
GeneOntologyCellularComponent	intermediate filament	KRTAP9-7 KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP4-6 KRTAP4-9 KRTAP11-1 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	2.15e-18	227	60	16	GO:0005882
GeneOntologyCellularComponent	intermediate filament cytoskeleton	KRTAP9-7 KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP4-6 KRTAP4-9 KRTAP11-1 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	2.28e-17	263	60	16	GO:0045111
GeneOntologyCellularComponent	pituitary gonadotropin complex	LHB CGB1 CGB2 CGB3 CGB7	9.14e-12	8	60	5	GO:0061696
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	KRTAP9-7 KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 TRIM55 KRTAP4-6 KRTAP4-9 KRTAP11-1 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	3.44e-10	899	60	17	GO:0099513
GeneOntologyCellularComponent	supramolecular fiber	KRTAP9-7 KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 TRIM55 KRTAP4-6 KRTAP4-9 KRTAP11-1 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	2.03e-08	1179	60	17	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	KRTAP9-7 KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 TRIM55 KRTAP4-6 KRTAP4-9 KRTAP11-1 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	2.24e-08	1187	60	17	GO:0099081
GeneOntologyCellularComponent	tetraspanin-enriched microdomain	TSPAN15 TSPAN33	3.59e-04	10	60	2	GO:0097197
GeneOntologyCellularComponent	extracellular matrix	ZAN OTOGL FGB SERAC1 MUC5B MUC5AC SVEP1	2.65e-03	656	60	7	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ZAN OTOGL FGB SERAC1 MUC5B MUC5AC SVEP1	2.70e-03	658	60	7	GO:0030312
GeneOntologyCellularComponent	Golgi lumen	LHB MUC5B MUC5AC	3.80e-03	109	60	3	GO:0005796
MousePheno	thin endometrium	LHB NPR2 CGB1 CGB2 CGB7	3.81e-10	15	39	5	MP:0008258
MousePheno	small vulva	LHB CGB1 CGB2 CGB7	7.73e-10	6	39	4	MP:0003527
MousePheno	small bulbourethral gland	LHB CGB1 CGB2 CGB7	1.80e-09	7	39	4	MP:0013737
MousePheno	small external male genitalia	LHB CGB1 CGB2 CGB7	3.59e-09	8	39	4	MP:0009202
MousePheno	abnormal bulbourethral gland morphology	LHB CGB1 CGB2 CGB7	2.52e-08	12	39	4	MP:0001169
MousePheno	abnormal Leydig cell differentiation	LHB CGB1 CGB2 CGB7	9.19e-08	16	39	4	MP:0013602
MousePheno	absent estrous cycle	LHB NPR2 CGB1 CGB2 CGB7	1.30e-07	44	39	5	MP:0009009
MousePheno	small prostate gland	LHB CGB1 CGB2 CGB7	1.95e-07	19	39	4	MP:0002774
MousePheno	abnormal endometrium morphology	LHB NPR2 CGB1 CGB2 CGB7	2.26e-07	49	39	5	MP:0004896
MousePheno	abnormal external female genitalia morphology	LHB CGB1 CGB2 CGB7	2.99e-07	21	39	4	MP:0003126
MousePheno	abnormal sex gland secretion	LHB CGB1 CGB2 CGB7	4.41e-07	23	39	4	MP:0002779
MousePheno	uterus hypoplasia	LHB CGB1 CGB2 CGB7	4.41e-07	23	39	4	MP:0001121
MousePheno	abnormal tertiary ovarian follicle morphology	LHB CGB1 CGB2 CGB7 FST	4.88e-07	57	39	5	MP:0009363
MousePheno	decreased circulating testosterone level	LHB NPR1 CGB1 CGB2 CGB7	6.33e-07	60	39	5	MP:0002780
MousePheno	abnormal corpus luteum morphology	LHB GJA4 NPR2 CGB1 CGB2 CGB7	7.48e-07	116	39	6	MP:0002679
MousePheno	absent corpus luteum	LHB NPR2 CGB1 CGB2 CGB7	1.02e-06	66	39	5	MP:0001134
MousePheno	decreased Leydig cell number	LHB CGB1 CGB2 CGB7	1.17e-06	29	39	4	MP:0005536
MousePheno	small epididymis	LHB CGB1 CGB2 CGB7 ADIPOR2	1.37e-06	70	39	5	MP:0004930
MousePheno	decreased circulating progesterone level	LHB CGB1 CGB2 CGB7	2.86e-06	36	39	4	MP:0005185
MousePheno	abnormal circulating testosterone level	LHB NPR1 CGB1 CGB2 CGB7	3.41e-06	84	39	5	MP:0005180
MousePheno	abnormal circulating androgen level	LHB NPR1 CGB1 CGB2 CGB7	3.41e-06	84	39	5	MP:0009819
MousePheno	decreased circulating estradiol level	LHB CGB1 CGB2 CGB7	3.57e-06	38	39	4	MP:0005181
MousePheno	absent mature ovarian follicles	LHB CGB1 CGB2 CGB7	4.40e-06	40	39	4	MP:0001132
MousePheno	decreased circulating estrogen level	LHB CGB1 CGB2 CGB7	4.86e-06	41	39	4	MP:0003371
MousePheno	abnormal testosterone level	LHB NPR1 CGB1 CGB2 CGB7	5.34e-06	92	39	5	MP:0011385
MousePheno	small uterus	LHB NPR2 CGB1 CGB2 CGB7	5.34e-06	92	39	5	MP:0002637
MousePheno	abnormal prostate gland size	LHB CGB1 CGB2 CGB7	5.36e-06	42	39	4	MP:0004959
MousePheno	ovary cyst	LHB CGB1 CGB2 CGB7	7.76e-06	46	39	4	MP:0002016
MousePheno	abnormal circulating progesterone level	LHB CGB1 CGB2 CGB7	1.09e-05	50	39	4	MP:0005184
MousePheno	abnormal oogenesis	LHB GJA4 NPR2 CGB1 CGB2 CGB7	1.16e-05	186	39	6	MP:0001931
MousePheno	abnormal circulating estradiol level	LHB CGB1 CGB2 CGB7	1.27e-05	52	39	4	MP:0005183
MousePheno	abnormal external male genitalia morphology	LHB CGB1 CGB2 CGB7	1.37e-05	53	39	4	MP:0009199
MousePheno	abnormal progesterone level	LHB CGB1 CGB2 CGB7	1.48e-05	54	39	4	MP:0011384
MousePheno	abnormal circulating estrogen level	LHB CGB1 CGB2 CGB7	1.84e-05	57	39	4	MP:0003369
MousePheno	abnormal estrous cycle	LHB NPR2 CGB1 CGB2 CGB7	1.95e-05	120	39	5	MP:0001927
MousePheno	abnormal ovulation cycle	LHB NPR2 CGB1 CGB2 CGB7	2.47e-05	126	39	5	MP:0009344
MousePheno	abnormal ovary morphology	LHB GJA4 NPR2 CGB1 CGB2 CGB7 SERAC1 FST	2.81e-05	451	39	8	MP:0001126
MousePheno	abnormal sex gland physiology	LHB NPR1 CGB1 CGB2 CGB7	3.83e-05	138	39	5	MP:0005647
MousePheno	abnormal female reproductive gland morphology	LHB GJA4 NPR2 CGB1 CGB2 CGB7 SERAC1 FST	4.07e-05	475	39	8	MP:0013324
MousePheno	abnormal prostate gland morphology	LHB CGB1 CGB2 CGB7	4.90e-05	73	39	4	MP:0001158
MousePheno	decreased mature ovarian follicle number	LHB CGB1 CGB2 CGB7	4.90e-05	73	39	4	MP:0002682
MousePheno	abnormal mature ovarian follicle morphology	LHB CGB1 CGB2 CGB7	6.36e-05	78	39	4	MP:0009364
MousePheno	abnormal Leydig cell morphology	LHB CGB1 CGB2 CGB7	7.74e-05	82	39	4	MP:0002786
MousePheno	abnormal epididymis size	LHB CGB1 CGB2 CGB7 ADIPOR2	9.23e-05	166	39	5	MP:0004926
MousePheno	abnormal testis interstitial tissue morphology	LHB CGB1 CGB2 CGB7	9.32e-05	86	39	4	MP:0011416
MousePheno	abnormal uterus size	LHB NPR2 CGB1 CGB2 CGB7	9.77e-05	168	39	5	MP:0004902
MousePheno	female infertility	JAG2 LHB GJA4 NPR2 CGB1 CGB2 CGB7	1.21e-04	410	39	7	MP:0001926
MousePheno	small ovary	LHB NPR2 CGB1 CGB2 CGB7	1.28e-04	178	39	5	MP:0001127
MousePheno	decreased oocyte number	LHB CGB1 CGB2 CGB7	1.37e-04	95	39	4	MP:0005431
MousePheno	abnormal oocyte number	LHB CGB1 CGB2 CGB7	1.43e-04	96	39	4	MP:0020152
MousePheno	abnormal ovarian follicle number	LHB CGB1 CGB2 CGB7 FST	2.37e-04	203	39	5	MP:0008871
MousePheno	abnormal cell differentiation	PLEK2 LHB GJA4 NPR2 CGB1 CGB2 RTN4R CGB7 FST	2.69e-04	795	39	9	MP:0005076
MousePheno	small seminal vesicle	LHB CGB1 CGB2 CGB7	3.16e-04	118	39	4	MP:0001157
MousePheno	abnormal ovarian folliculogenesis	LHB CGB1 CGB2 CGB7	3.37e-04	120	39	4	MP:0001130
MousePheno	abnormal ovary size	LHB NPR2 CGB1 CGB2 CGB7	4.05e-04	228	39	5	MP:0004853
MousePheno	abnormal ovarian follicle morphology	LHB CGB1 CGB2 CGB7 FST	5.62e-04	245	39	5	MP:0001131
MousePheno	abnormal oocyte morphology	LHB CGB1 CGB2 CGB7	5.72e-04	138	39	4	MP:0001125
MousePheno	abnormal seminal vesicle size	LHB CGB1 CGB2 CGB7	7.44e-04	148	39	4	MP:0004907
MousePheno	abnormal female germ cell morphology	LHB CGB1 CGB2 CGB7	7.82e-04	150	39	4	MP:0006361
MousePheno	abnormal epididymis morphology	LHB CGB1 CGB2 CGB7 ADIPOR2	8.57e-04	269	39	5	MP:0002631
MousePheno	abnormal internal female genitalia morphology	LHB GJA4 NPR2 CGB1 CGB2 CGB7 SERAC1 FST	9.81e-04	757	39	8	MP:0009209
MousePheno	abnormal female genitalia morphology	LHB GJA4 NPR2 CGB1 CGB2 CGB7 SERAC1 FST	1.03e-03	763	39	8	MP:0009208
MousePheno	abnormal female reproductive system morphology	LHB GJA4 NPR2 CGB1 CGB2 CGB7 SERAC1 FST	1.06e-03	766	39	8	MP:0001119
MousePheno	abnormal quadriceps weight	TRIM55 FST	1.26e-03	19	39	2	MP:0020164
MousePheno	abnormal seminal vesicle morphology	TSPAN15 LHB CGB1 CGB2 CGB7	1.83e-03	319	39	5	MP:0002059
MousePheno	abnormal quadriceps morphology	TRIM55 FST	2.18e-03	25	39	2	MP:0010225
MousePheno	abnormal female reproductive system physiology	JAG2 LHB GJA4 NPR2 CGB1 CGB2 CGB7 FST	2.49e-03	876	39	8	MP:0003699
Domain	KAP	KRTAP9-7 KRTAP4-7 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP4-6 KRTAP4-9 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	9.04e-26	58	58	15	IPR002494
Domain	Keratin_B2_2	KRTAP9-7 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP4-6 KRTAP16-1 KRTAP10-11 KRTAP10-7	1.48e-19	39	58	11	PF13885
Domain	Keratin_B2	KRTAP4-7 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP4-11 KRTAP4-6 KRTAP4-9 KRTAP10-11	2.90e-17	40	58	10	PF01500
Domain	Glyco_hormone_CN	LHB CGB1 CGB3 CGB7 MUC5B MUC5AC	3.37e-12	15	58	6	IPR006208
Domain	Cys_knot	LHB CGB1 CGB3 CGB7 MUC5B MUC5AC	3.37e-12	15	58	6	PF00007
Domain	Gonadotropin_bsu_CS	LHB CGB1 CGB3 CGB7	1.25e-09	6	58	4	IPR018245
Domain	Gonadotropin_bsu	LHB CGB1 CGB3 CGB7	2.91e-09	7	58	4	IPR001545
Domain	GLYCO_HORMONE_BETA_2	LHB CGB1 CGB3 CGB7	2.91e-09	7	58	4	PS00689
Domain	GHB	LHB CGB1 CGB3 CGB7	2.91e-09	7	58	4	SM00068
Domain	GLYCO_HORMONE_BETA_1	LHB CGB1 CGB3 CGB7	2.91e-09	7	58	4	PS00261
Domain	VWFC_1	JAG2 CHRDL2 ZAN MUC5B MUC5AC	8.48e-08	36	58	5	PS01208
Domain	VWC	JAG2 CHRDL2 ZAN MUC5B MUC5AC	1.12e-07	38	58	5	SM00214
Domain	VWFC_2	JAG2 CHRDL2 ZAN MUC5B MUC5AC	1.12e-07	38	58	5	PS50184
Domain	VWF_dom	JAG2 CHRDL2 ZAN MUC5B MUC5AC	1.89e-07	42	58	5	IPR001007
Domain	VWC_out	JAG2 ZAN MUC5B MUC5AC	3.13e-07	19	58	4	SM00215
Domain	TIL	ZAN MUC5B MUC5AC	6.13e-06	12	58	3	PF01826
Domain	C8	ZAN MUC5B MUC5AC	6.13e-06	12	58	3	PF08742
Domain	PMG	KRTAP13-4 KRTAP12-2 KRTAP11-1	7.95e-06	13	58	3	PF05287
Domain	Unchr_dom_Cys-rich	ZAN MUC5B MUC5AC	7.95e-06	13	58	3	IPR014853
Domain	KRTAP_PMG	KRTAP13-4 KRTAP12-2 KRTAP11-1	7.95e-06	13	58	3	IPR007951
Domain	C8	ZAN MUC5B MUC5AC	7.95e-06	13	58	3	SM00832
Domain	TIL_dom	ZAN MUC5B MUC5AC	1.01e-05	14	58	3	IPR002919
Domain	VWFD	ZAN MUC5B MUC5AC	1.55e-05	16	58	3	PS51233
Domain	VWD	ZAN MUC5B MUC5AC	1.55e-05	16	58	3	SM00216
Domain	VWF_type-D	ZAN MUC5B MUC5AC	1.55e-05	16	58	3	IPR001846
Domain	VWD	ZAN MUC5B MUC5AC	1.55e-05	16	58	3	PF00094
Domain	ANF_RECEPTORS	NPR1 NPR2	2.84e-05	3	58	2	PS00458
Domain	ANPR/GUC	NPR1 NPR2	2.84e-05	3	58	2	IPR001170
Domain	-	LHB CGB1 CGB3 CGB7	5.55e-05	67	58	4	2.10.90.10
Domain	Cystine-knot_cytokine	LHB CGB1 CGB3 CGB7	5.55e-05	67	58	4	IPR029034
Domain	VWC	CHRDL2 MUC5B MUC5AC	8.81e-05	28	58	3	PF00093
Domain	WxxW_domain	MUC5B MUC5AC	1.41e-04	6	58	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC5AC	1.41e-04	6	58	2	PF13330
Domain	EGF	JAG2 ZAN LRP1B SVEP1	6.32e-04	126	58	4	PF00008
Domain	EGF_extracell	JAG2 LRP1B SVEP1	8.58e-04	60	58	3	IPR013111
Domain	EGF_2	JAG2 LRP1B SVEP1	8.58e-04	60	58	3	PF07974
Domain	A/G_cyclase_CS	NPR1 NPR2	1.25e-03	17	58	2	IPR018297
Domain	CTCK_1	MUC5B MUC5AC	1.40e-03	18	58	2	PS01185
Domain	Nucleotide_cyclase	NPR1 NPR2	1.40e-03	18	58	2	IPR029787
Domain	KAZAL_1	FSTL4 FST	1.40e-03	18	58	2	PS00282
Domain	-	NPR1 NPR2	1.40e-03	18	58	2	3.30.70.1230
Domain	GUANYLATE_CYCLASE_2	NPR1 NPR2	1.57e-03	19	58	2	PS50125
Domain	GUANYLATE_CYCLASE_1	NPR1 NPR2	1.57e-03	19	58	2	PS00452
Domain	A/G_cyclase	NPR1 NPR2	1.57e-03	19	58	2	IPR001054
Domain	CYCc	NPR1 NPR2	1.57e-03	19	58	2	SM00044
Domain	Guanylate_cyc	NPR1 NPR2	1.57e-03	19	58	2	PF00211
Domain	ZF_RING_1	RNF144B RAD18 TRIM55 DCST1 BRAP	2.07e-03	291	58	5	PS00518
Domain	Kazal_1	FSTL4 FST	2.10e-03	22	58	2	PF00050
Domain	TNFR_c6	TNFRSF8 LTBR	2.10e-03	22	58	2	PF00020
Domain	CT	MUC5B MUC5AC	2.10e-03	22	58	2	SM00041
Domain	ZF_RING_2	RNF144B RAD18 TRIM55 DCST1 BRAP	2.30e-03	298	58	5	PS50089
Domain	EGF_CA	JAG2 LRP1B SVEP1	2.42e-03	86	58	3	PF07645
Domain	RING	RNF144B RAD18 TRIM55 DCST1 BRAP	2.54e-03	305	58	5	SM00184
Domain	Cys_knot_C	MUC5B MUC5AC	2.72e-03	25	58	2	IPR006207
Domain	CTCK_2	MUC5B MUC5AC	2.72e-03	25	58	2	PS01225
Domain	TNFR	TNFRSF8 LTBR	2.94e-03	26	58	2	SM00208
Domain	Znf_RING	RNF144B RAD18 TRIM55 DCST1 BRAP	3.38e-03	326	58	5	IPR001841
Domain	hEGF	JAG2 SVEP1	3.40e-03	28	58	2	PF12661
Domain	EGF_Ca-bd_CS	JAG2 LRP1B SVEP1	3.41e-03	97	58	3	IPR018097
Domain	EGF_CA	JAG2 LRP1B SVEP1	3.61e-03	99	58	3	PS01187
Domain	TNFR_NGFR_1	TNFRSF8 LTBR	3.65e-03	29	58	2	PS00652
Domain	TNFR_NGFR_2	TNFRSF8 LTBR	3.65e-03	29	58	2	PS50050
Domain	ASX_HYDROXYL	JAG2 LRP1B SVEP1	3.71e-03	100	58	3	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	JAG2 LRP1B SVEP1	4.37e-03	106	58	3	IPR000152
Domain	Tetraspanin	TSPAN15 TSPAN33	4.43e-03	32	58	2	IPR000301
Domain	Tetraspanin_EC2	TSPAN15 TSPAN33	4.43e-03	32	58	2	IPR008952
Domain	Tetraspannin	TSPAN15 TSPAN33	4.70e-03	33	58	2	PF00335
Domain	Tetraspanin/Peripherin	TSPAN15 TSPAN33	4.70e-03	33	58	2	IPR018499
Domain	TNFR/NGFR_Cys_rich_reg	TNFRSF8 LTBR	4.70e-03	33	58	2	IPR001368
Domain	Kazal_2	FSTL4 FST	5.58e-03	36	58	2	PF07648
Domain	ANF_receptor	NPR1 NPR2	5.89e-03	37	58	2	PF01094
Domain	ANF_lig-bd_rcpt	NPR1 NPR2	5.89e-03	37	58	2	IPR001828
Domain	EGF_3	JAG2 ZAN LRP1B SVEP1	6.09e-03	235	58	4	PS50026
Domain	EGF	JAG2 ZAN LRP1B SVEP1	6.09e-03	235	58	4	SM00181
Pathway	REACTOME_KERATINIZATION	KRTAP9-7 KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP4-6 KRTAP4-9 KRTAP11-1 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	8.63e-20	153	51	16	MM15343
Pathway	REACTOME_KERATINIZATION	KRTAP9-7 KRTAP4-7 KRTAP13-4 KRTAP4-5 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP4-6 KRTAP4-9 KRTAP11-1 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	2.54e-17	217	51	16	M27640
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	KRTAP9-7 KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP4-6 KRTAP4-9 KRTAP11-1 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	1.20e-11	502	51	16	MM14537
Pathway	REACTOME_MINERALOCORTICOID_BIOSYNTHESIS	LHB CGB1 CGB2 CGB7	7.36e-08	12	51	4	MM14749
Pathway	REACTOME_GLYCOPROTEIN_HORMONES	LHB CGB1 CGB2 CGB7	1.06e-07	13	51	4	MM14830
Pathway	REACTOME_REACTIONS_SPECIFIC_TO_THE_COMPLEX_N_GLYCAN_SYNTHESIS_PATHWAY	LHB CGB1 CGB2 CGB7	1.06e-07	13	51	4	MM15701
Pathway	REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS	LHB CGB1 CGB2 CGB7	2.01e-07	15	51	4	MM14832
Pathway	REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS	LHB CGB1 CGB2 CGB7	2.01e-07	15	51	4	MM14972
Pathway	REACTOME_ANDROGEN_BIOSYNTHESIS	LHB CGB1 CGB2 CGB7	2.01e-07	15	51	4	MM14739
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	KRTAP9-7 KRTAP4-7 KRTAP13-4 KRTAP4-5 KRTAP4-8 KRTAP12-2 UNC5B KRTAP10-10 KRTAP12-1 KRTAP4-11 KPRP KRTAP4-6 KRTAP4-9 KRTAP11-1 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	1.26e-06	1432	51	18	M509
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS	LHB CGB1 CGB2 CGB7	2.14e-06	26	51	4	MM15502
Pathway	REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI	LHB CGB1 CGB2 CGB7	3.38e-06	29	51	4	MM15699
Pathway	REACTOME_METABOLISM_OF_STEROID_HORMONES	LHB CGB1 CGB2 CGB7	1.39e-05	41	51	4	MM14757
Pathway	REACTOME_PEPTIDE_HORMONE_METABOLISM	LHB CGB1 CGB2 CGB7	1.17e-04	70	51	4	MM14916
Pathway	REACTOME_PHYSIOLOGICAL_FACTORS	NPR1 NPR2	2.66e-04	7	51	2	MM15201
Pathway	REACTOME_METABOLISM_OF_STEROIDS	LHB CGB1 CGB2 CGB7	1.10e-03	126	51	4	MM15553
Pathway	REACTOME_PHYSIOLOGICAL_FACTORS	NPR1 NPR2	1.14e-03	14	51	2	M27459
Pathway	REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS	LHB CGB3	1.14e-03	14	51	2	M756
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC5B MUC5AC	1.49e-03	16	51	2	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC5B MUC5AC	1.69e-03	17	51	2	M27412
Pathway	REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	LHB CGB1 CGB2 CGB7	1.75e-03	143	51	4	MM15055
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC5B MUC5AC	2.58e-03	21	51	2	MM15706
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC5B MUC5AC	3.09e-03	23	51	2	M556
Pubmed	Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair.	KRTAP9-7 KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP4-6 KRTAP11-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	7.49e-26	69	61	14	18721477
Pubmed	Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.	KRTAP9-7 KRTAP4-7 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP4-11 KRTAP4-6 KRTAP4-9 KRTAP16-1	1.01e-17	37	61	9	11279113
Pubmed	A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.	KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	1.79e-13	16	61	6	15028290
Pubmed	Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone.	LHB CGB1 CGB2 CGB3 CGB7	2.94e-13	7	61	5	6690982
Pubmed	Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone.	LHB NPR2 CGB1 CGB2 CGB7	7.83e-13	8	61	5	26522847
Pubmed	Size polymorphisms in the human ultrahigh sulfur hair keratin-associated protein 4, KAP4, gene family.	KRTAP4-7 KRTAP4-5 KRTAP4-8 KRTAP4-11 KRTAP4-6	7.83e-13	8	61	5	15955084
Pubmed	Luteinizing hormone induction of ovarian tumors: oligogenic differences between mouse strains dictates tumor disposition.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	10618427
Pubmed	Androgen-responsive microRNAs in mouse Sertoli cells.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	22911753
Pubmed	Cloning of the mouse gonadotropin beta-subunit-encoding genes, II. Structure of the luteinizing hormone beta-subunit-encoding genes.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	8543188
Pubmed	Hypogonadism caused by a single amino acid substitution in the beta subunit of luteinizing hormone.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	1727547
Pubmed	Targeted overexpression of luteinizing hormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	7877975
Pubmed	Luteinizing hormone beta promoter stimulation by adenylyl cyclase and cooperation with gonadotropin-releasing hormone 1 in transgenic mice and LBetaT2 Cells.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	17699734
Pubmed	The pleiotropic effects of excessive luteinizing hormone secretion in transgenic mice.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	17710732
Pubmed	Targeted disruption of luteinizing hormone beta-subunit leads to hypogonadism, defects in gonadal steroidogenesis, and infertility.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	15569941
Pubmed	Sulfation of LH does not affect intracellular trafficking.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	19647136
Pubmed	Expression of the beta subunit of chorionic gonadotropin in transgenic mice.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	7508931
Pubmed	Elevated luteinizing hormone in prepubertal transgenic mice causes hyperandrogenemia, precocious puberty, and substantial ovarian pathology.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	9231809
Pubmed	Targeted overexpression of luteinizing hormone causes ovary-dependent functional adenomas restricted to cells of the Pit-1 lineage.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	12960102
Pubmed	Ovulatory surges of human CG prevent hormone-induced granulosa cell tumor formation leading to the identification of tumor-associated changes in the transcriptome.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	12040011
Pubmed	An Otx-related homeodomain protein binds an LHbeta promoter element important for activation during gonadotrope maturation.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	12040015
Pubmed	Transgenic mice with chronically elevated luteinizing hormone are infertile due to anovulation, defects in uterine receptivity, and midgestation pregnancy failure.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	10342846
Pubmed	Stress levels of glucocorticoids inhibit LHβ-subunit gene expression in gonadotrope cells.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	22851703
Pubmed	The role of luteinizing hormone-beta gene polymorphism in the onset and progression of puberty in healthy boys.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	8784083
Pubmed	An i-motif-regulated enhancer, eRNA and adjacent lncRNA affect Lhb expression through distinct mechanisms in a sex-specific context.	LHB CGB1 CGB2 CGB7	4.28e-11	5	61	4	39158745
Pubmed	Effect of Soluble Adenylyl Cyclase (ADCY10) Inhibitors on the LH-Stimulated cAMP Synthesis in Mltc-1 Leydig Cell Line.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	33924969
Pubmed	The beta subunit of human chorionic gonadotropin is encoded by multiple genes.	CGB1 CGB2 CGB3 CGB7	1.28e-10	6	61	4	6194155
Pubmed	Development of a methodology for and assessment of pulsatile luteinizing hormone secretion in juvenile and adult male mice.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	24092638
Pubmed	Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	14871891
Pubmed	Identification of the transcriptionally active genes of the chorionic gonadotropin beta gene cluster in vivo.	CGB1 CGB2 CGB3 CGB7	1.28e-10	6	61	4	1371113
Pubmed	AMP-activated protein kinase is a key intermediary in GnRH-stimulated LHβ gene transcription.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	23518923
Pubmed	Free fatty acids induce Lhb mRNA but suppress Fshb mRNA in pituitary LβT2 gonadotropes and diet-induced obesity reduces FSH levels in male mice and disrupts the proestrous LH/FSH surge in female mice.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	23525221
Pubmed	Maximal activity of the luteinizing hormone beta-subunit gene requires beta-catenin.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	17244763
Pubmed	The human genome contains seven genes for the beta-subunit of chorionic gonadotropin but only one gene for the beta-subunit of luteinizing hormone.	CGB1 CGB2 CGB3 CGB7	1.28e-10	6	61	4	6319099
Pubmed	The role of amino acid neurotransmitters in the regulation of pituitary gonadotropin release in fish.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	10949077
Pubmed	Secretoneurin stimulates the production and release of luteinizing hormone in mouse L{beta}T2 gonadotropin cells.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	21521715
Pubmed	Dependence of uterine cyclooxygenase2 expression on luteinizing hormone signaling.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	15814897
Pubmed	Prolactin regulation of gonadotropin-releasing hormone neurons to suppress luteinizing hormone secretion in mice.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	17569755
Pubmed	Functional analysis of LHbeta knockout mice.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	17350160
Pubmed	Ablation of GalNAc-4-sulfotransferase-1 enhances reproduction by altering the carbohydrate structures of luteinizing hormone in mice.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	18431515
Pubmed	The calcium component of gonadotropin-releasing hormone-stimulated luteinizing hormone subunit gene transcription is mediated by calcium/calmodulin-dependent protein kinase type II.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	12746302
Pubmed	Distinct mechanisms involving diverse histone deacetylases repress expression of the two gonadotropin beta-subunit genes in immature gonadotropes, and their actions are overcome by gonadotropin-releasing hormone.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	17371839
Pubmed	Differential activation of the luteinizing hormone beta-subunit promoter by activin and gonadotropin-releasing hormone: a role for the mitogen-activated protein kinase signaling pathway in LbetaT2 gonadotrophs.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	13679314
Pubmed	Increases in luteinizing hormone are associated with declines in cognitive performance.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	17376589
Pubmed	Luteinizing hormone promotes gonadal tumorigenesis in inhibin-deficient mice.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	18657590
Pubmed	The beta chorionic gonadotropin-beta luteinizing gene cluster maps to human chromosome 19.	CGB1 CGB2 CGB3 CGB7	1.28e-10	6	61	4	6204923
Pubmed	Different signaling pathways control acute induction versus long-term repression of LHbeta transcription by GnRH.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	12193554
Pubmed	The role of endocannabinoids in the regulation of luteinizing hormone and prolactin release. Differences between the effects of AEA and 2AG.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	18308464
Pubmed	CREB binding protein (CBP) activation is required for luteinizing hormone beta expression and normal fertility in mice.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	22508984
Pubmed	A new role for wilms tumor protein 1: differential activities of + KTS and -KTS variants to regulate LHβ transcription.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	25617744
Pubmed	A map of the hCG beta-LH beta gene cluster.	CGB1 CGB2 CGB3 CGB7	1.28e-10	6	61	4	2422163
Pubmed	Development of leydig cells in the insulin-like growth factor-I (igf-I) knockout mouse: effects of igf-I replacement and gonadotropic stimulation.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	14585811
Pubmed	The lack of estrogen and excess luteinizing hormone are responsible for the female ArKO mouse phenotype.	LHB CGB1 CGB2 CGB7	1.28e-10	6	61	4	20546829
Pubmed	Early growth response protein 1 binds to the luteinizing hormone-beta promoter and mediates gonadotropin-releasing hormone-stimulated gene expression.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	10319325
Pubmed	Icam5 Expression Exhibits Sex Differences in the Neonatal Pituitary and Is Regulated by Estradiol and Bisphenol A.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	26789235
Pubmed	Embryonic expression of the luteinizing hormone beta gene appears to be coupled to the transient appearance of p8, a high mobility group-related transcription factor.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	12429736
Pubmed	Expression of the pituitary adenylate cyclase-activating polypeptide (PACAP) type 1 receptor (PAC1R) potentiates the effects of GnRH on gonadotropin subunit gene expression.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	21658369
Pubmed	Redirecting intracellular trafficking and the secretion pattern of FSH dramatically enhances ovarian function in mice.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	24706813
Pubmed	Disruption of the single copy gonadotropin-releasing hormone receptor in mice by gene trap: severe reduction of reproductive organs and functions in developing and adult mice.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	20068010
Pubmed	Reference intervals for serum testosterone, SHBG, LH and FSH in males from the NORIP project.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	19929279
Pubmed	Activin induces x-zone apoptosis that inhibits luteinizing hormone-dependent adrenocortical tumor formation in inhibin-deficient mice.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	12748296
Pubmed	Assignment of the genes for the alpha and beta subunits of thyrotropin to different mouse chromosomes.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	6582507
Pubmed	Regulation of LH/FSH expression by secretoglobin 3A2 in the mouse pituitary gland.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	24514953
Pubmed	Biphasic Roles of Clock Genes and Bone Morphogenetic Proteins in Gonadotropin Expression by Mouse Gonadotrope Cells.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	34681844
Pubmed	FOXO1 transcription factor inhibits luteinizing hormone β gene expression in pituitary gonadotrope cells.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	22865884
Pubmed	PPARγ co-activator-1α co-activates steroidogenic factor 1 to stimulate the synthesis of luteinizing hormone and aldosterone.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	21108604
Pubmed	Ovulation involves the luteinizing hormone-dependent activation of G(q/11) in granulosa cells.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	23836924
Pubmed	Pulse sensitivity of the luteinizing hormone beta promoter is determined by a negative feedback loop Involving early growth response-1 and Ngfi-A binding protein 1 and 2.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	17299135
Pubmed	Evidence for cross-talk between the LH receptor and LH during implantation in mice.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	23464498
Pubmed	The orphan nuclear receptors COUP-TFI and COUP-TFII regulate expression of the gonadotropin LHβ gene.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	20797425
Pubmed	Mutual Effects of Orexin and Bone Morphogenetic Proteins on Gonadotropin Expression by Mouse Gonadotrope Cells.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	36077179
Pubmed	Cyclic GMP signaling is involved in the luteinizing hormone-dependent meiotic maturation of mouse oocytes.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	19474061
Pubmed	Anterior pituitary development: short tales from dwarf mice.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	1505020
Pubmed	A null mutation in basigin, an immunoglobulin superfamily member, indicates its important roles in peri-implantation development and spermatogenesis.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	9501026
Pubmed	Stress rapidly suppresses in vivo LH pulses and increases activation of RFRP-3 neurons in male mice.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	30382693
Pubmed	Absent Progesterone Signaling in Kisspeptin Neurons Disrupts the LH Surge and Impairs Fertility in Female Mice.	LHB CGB1 CGB2 CGB7	2.98e-10	7	61	4	26076042
Pubmed	LIM homeodomain transcription factor Isl-1 enhances follicle stimulating hormone-beta and luteinizing hormone-beta gene expression and mediates the activation of leptin on gonadotropin synthesis.	LHB CGB1 CGB2 CGB7	5.96e-10	8	61	4	20702576
Pubmed	The polycystic ovary syndrome-associated gene Yap1 is regulated by gonadotropins and sex steroid hormones in hyperandrogenism-induced oligo-ovulation in mouse.	LHB CGB1 CGB2 CGB7	5.96e-10	8	61	4	28961951
Pubmed	Gonadotrope-specific deletion of Dicer results in severely suppressed gonadotropins and fertility defects.	LHB CGB1 CGB2 CGB7	5.96e-10	8	61	4	25525274
Pubmed	Gonadotrope and thyrotrope development in the human and mouse anterior pituitary gland.	LHB CGB1 CGB2 CGB7	5.96e-10	8	61	4	16806148
Pubmed	Transforming growth factor-beta1 null mutation causes infertility in male mice associated with testosterone deficiency and sexual dysfunction.	LHB CGB1 CGB2 CGB7	5.96e-10	8	61	4	17478551
Pubmed	The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus.	LHB CGB1 CGB2 CGB7	5.96e-10	8	61	4	7659091
Pubmed	The transcription factor GATA4 is required for follicular development and normal ovarian function.	LHB CGB1 CGB2 CGB7 FST	8.97e-10	26	61	5	23769843
Pubmed	Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism.	LHB CGB1 CGB2 CGB7	1.07e-09	9	61	4	17959774
Pubmed	Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2.	LHB CGB1 CGB2 CGB7	1.07e-09	9	61	4	16537498
Pubmed	Pituitary homeobox 1 (Ptx1) is differentially expressed during pituitary development.	LHB CGB1 CGB2 CGB7	1.07e-09	9	61	4	10067870
Pubmed	Ontogeny of the prohormone convertases PC1 and PC2 in the mouse hypophysis and their colocalization with corticotropin and alpha-melanotropin.	LHB CGB1 CGB2 CGB7	1.07e-09	9	61	4	8389457
Pubmed	Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6.	LHB CGB1 CGB2 CGB7	1.07e-09	9	61	4	21228153
Pubmed	Chromosome assignment of genes encoding the alpha and beta subunits of glycoprotein hormones in man and mouse.	LHB CGB1 CGB2 CGB7	1.07e-09	9	61	4	6581542
Pubmed	Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty.	LHB CGB1 CGB2 CGB7 FST	1.10e-09	27	61	5	16384867
Pubmed	The mouse cyclin E maps to chromosome 7.	LHB CGB1 CGB2 CGB7	1.78e-09	10	61	4	8833259
Pubmed	Follicle-stimulating hormone synthesis and fertility depend on SMAD4 and FOXL2.	LHB CGB1 CGB2 CGB7	1.78e-09	10	61	4	24739304
Pubmed	Steroidogenic Factor 1 Regulates Transcription of the Inhibin B Coreceptor in Pituitary Gonadotrope Cells.	LHB CGB1 CGB2 CGB7	1.78e-09	10	61	4	35957608
Pubmed	Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis.	LHB CGB1 CGB2 CGB7	1.78e-09	10	61	4	23728177
Pubmed	Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21.	KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP10-7	2.80e-09	11	61	4	14962103
Pubmed	Location of the DBP transcription factor gene in human and mouse.	LHB CGB1 CGB2 CGB7	2.80e-09	11	61	4	8903733
Pubmed	Candidate genes for panhypopituitarism identified by gene expression profiling.	LHB CGB1 CGB2 CGB7	2.80e-09	11	61	4	21828248
Pubmed	Loss of the protein NUPR1 (p8) leads to delayed LHB expression, delayed ovarian maturation, and testicular development of a sertoli-cell-only syndrome-like phenotype in mice.	LHB CGB1 CGB2 CGB7	2.80e-09	11	61	4	18495683
Pubmed	Hes1 regulates formations of the hypophyseal pars tuberalis and the hypothalamus.	LHB CGB1 CGB2 CGB7	2.80e-09	11	61	4	20431921
Pubmed	Mutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans.	LHB CGB1 CGB2 CGB7	2.80e-09	11	61	4	16932809
Pubmed	Homeodomain Proteins SIX3 and SIX6 Regulate Gonadotrope-specific Genes During Pituitary Development.	LHB CGB1 CGB2 CGB7	2.80e-09	11	61	4	25915183
Interaction	HOXA1 interactions	JAG2 KRTAP4-7 CHRDL2 KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 RTN4R TRIM55 KPRP KRTAP11-1 FST KRTAP10-11 KRTAP10-7 KRTAP12-4	3.03e-18	356	57	18	int:HOXA1
Interaction	OTX1 interactions	RNF144B KRTAP4-7 CHRDL2 KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP12-1 KRTAP4-11 RTN4R KPRP KRTAP11-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	8.07e-18	155	57	14	int:OTX1
Interaction	LCE1B interactions	KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP11-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	3.79e-14	85	57	10	int:LCE1B
Interaction	LCE1F interactions	KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP11-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	8.61e-14	92	57	10	int:LCE1F
Interaction	LCE2A interactions	KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP12-1 KRTAP4-11 KRTAP11-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	2.97e-13	69	57	9	int:LCE2A
Interaction	LCE3A interactions	KRTAP4-5 KRTAP4-12 KRTAP12-1 KRTAP4-11 KPRP KRTAP11-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	7.36e-13	76	57	9	int:LCE3A
Interaction	SMCP interactions	KRTAP4-7 KRTAP4-5 KRTAP4-12 KRTAP12-1 KRTAP4-11 CGB3 KRTAP10-11 KRTAP10-7 KRTAP12-4	1.06e-12	79	57	9	int:SMCP
Interaction	POU4F2 interactions	CHRDL2 KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP12-1 KRTAP4-11 KPRP KRTAP10-11 KRTAP12-4	1.67e-12	83	57	9	int:POU4F2
Interaction	LCE1A interactions	KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP12-1 KRTAP4-11 KRTAP11-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	1.87e-12	84	57	9	int:LCE1A
Interaction	CATSPER1 interactions	KRTAP4-7 KRTAP4-12 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KPRP FST KRTAP10-11 KRTAP10-7	2.14e-12	126	57	10	int:CATSPER1
Interaction	KRTAP9-3 interactions	KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KPRP KRTAP11-1 KRTAP10-11 KRTAP10-7	6.18e-12	140	57	10	int:KRTAP9-3
Interaction	LCE3C interactions	KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP4-11 KPRP KRTAP11-1 KRTAP10-11 KRTAP10-7	1.41e-11	67	57	8	int:LCE3C
Interaction	LCE1E interactions	KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP10-11 KRTAP10-7 KRTAP12-4	1.59e-11	68	57	8	int:LCE1E
Interaction	LCE1C interactions	KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP10-11 KRTAP12-4	4.44e-11	77	57	8	int:LCE1C
Interaction	LCE2B interactions	KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP12-1 KRTAP4-11 KRTAP11-1 KRTAP10-11 KRTAP10-7	6.73e-11	81	57	8	int:LCE2B
Interaction	GPRIN2 interactions	KRTAP4-7 KRTAP4-12 KRTAP12-2 KRTAP12-1 TRIM55 KRTAP12-4	1.40e-10	28	57	6	int:GPRIN2
Interaction	LCE5A interactions	KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP12-1 KRTAP4-11 KRTAP10-11 KRTAP10-7 KRTAP12-4	1.59e-10	90	57	8	int:LCE5A
Interaction	KRTAP5-6 interactions	KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP11-1 KRTAP10-11 KRTAP10-7	2.27e-10	94	57	8	int:KRTAP5-6
Interaction	KRTAP5-9 interactions	KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KPRP KRTAP11-1 KRTAP10-11 KRTAP10-7	2.46e-10	203	57	10	int:KRTAP5-9
Interaction	NOTCH2NLA interactions	KRTAP4-7 KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KPRP KRTAP10-11 KRTAP10-7 KRTAP12-4	5.77e-10	381	57	12	int:NOTCH2NLA
Interaction	CREB5 interactions	RNF144B KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP4-11 KPRP FST KRTAP10-11 KRTAP10-7	8.08e-10	164	57	9	int:CREB5
Interaction	NBPF19 interactions	KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KPRP KRTAP10-11 KRTAP12-4	9.44e-10	233	57	10	int:NBPF19
Interaction	LCE3D interactions	KRTAP4-5 KRTAP4-12 KRTAP4-11 KPRP KRTAP10-11 KRTAP10-7 KRTAP12-4	1.39e-09	73	57	7	int:LCE3D
Interaction	LCE4A interactions	KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP4-11 KRTAP10-11 KRTAP10-7 KRTAP12-4	2.68e-09	80	57	7	int:LCE4A
Interaction	KRTAP4-4 interactions	KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP10-11 KRTAP10-7	2.92e-09	81	57	7	int:KRTAP4-4
Interaction	LCE3B interactions	KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP4-11 KRTAP10-11 KRTAP10-7	3.35e-09	46	57	6	int:LCE3B
Interaction	KRTAP4-2 interactions	KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP4-11 KPRP KRTAP11-1 KRTAP10-11 KRTAP10-7	3.45e-09	132	57	8	int:KRTAP4-2
Interaction	LCE2C interactions	KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP10-7 KRTAP12-4	5.26e-09	88	57	7	int:LCE2C
Interaction	KRTAP9-2 interactions	KRTAP4-7 KRTAP4-5 KRTAP4-12 KRTAP12-1 KRTAP4-11 KRTAP11-1 KRTAP10-11 KRTAP10-7	8.99e-09	149	57	8	int:KRTAP9-2
Interaction	KRTAP10-8 interactions	KRTAP4-7 KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KPRP KRTAP11-1 KRTAP10-11 KRTAP10-7	1.37e-08	401	57	11	int:KRTAP10-8
Interaction	CYSRT1 interactions	KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KPRP KRTAP11-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	1.56e-08	511	57	12	int:CYSRT1
Interaction	KRTAP10-5 interactions	KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP12-1 KRTAP4-11 KRTAP11-1 KRTAP10-11 KRTAP10-7	1.57e-08	160	57	8	int:KRTAP10-5
Interaction	LCE3E interactions	KRTAP4-5 KRTAP4-12 KRTAP4-11 KPRP KRTAP10-11 KRTAP10-7	1.74e-08	60	57	6	int:LCE3E
Interaction	CRCT1 interactions	KRTAP4-5 KRTAP4-12 KRTAP4-11 TRIM55 KRTAP10-11 KRTAP10-7	3.11e-08	66	57	6	int:CRCT1
Interaction	KRTAP5-3 interactions	KRTAP4-5 KRTAP4-12 KRTAP4-11 KPRP KRTAP11-1 KRTAP10-7	3.11e-08	66	57	6	int:KRTAP5-3
Interaction	KRTAP5-7 interactions	KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP4-11 KPRP KRTAP10-11	4.85e-08	71	57	6	int:KRTAP5-7
Interaction	VGLL3 interactions	KRTAP12-2 KRTAP12-1 KRTAP4-11 KPRP KRTAP11-1 KRTAP10-7	5.28e-08	72	57	6	int:VGLL3
Interaction	ZNF587 interactions	CHRDL2 KRTAP12-2 KRTAP10-10 KPRP FST KRTAP10-11 KRTAP10-7	1.04e-07	135	57	7	int:ZNF587
Interaction	KRTAP26-1 interactions	KRTAP4-7 KRTAP4-12 KRTAP12-2 KRTAP12-1 KRTAP11-1 KRTAP10-7	2.62e-07	94	57	6	int:KRTAP26-1
Interaction	FAM76B interactions	KRTAP4-7 KRTAP4-5 KRTAP4-12 KRTAP4-11 KRTAP10-11 KRTAP10-7	3.57e-07	99	57	6	int:FAM76B
Interaction	KRTAP9-8 interactions	KRTAP4-5 KRTAP12-2 KRTAP4-11 KRTAP11-1 KRTAP10-11 KRTAP10-7	3.79e-07	100	57	6	int:KRTAP9-8
Interaction	FBXO34 interactions	KRTAP4-5 KRTAP4-12 KRTAP4-11 KRTAP10-11 KRTAP12-4	4.72e-07	55	57	5	int:FBXO34
Interaction	SPATA3 interactions	KRTAP4-12 KRTAP12-2 KRTAP10-11 KRTAP10-7	5.86e-07	24	57	4	int:SPATA3
Interaction	SPRY1 interactions	KRTAP4-12 KRTAP12-2 KPRP KRTAP11-1 KRTAP10-11 KRTAP10-7	7.04e-07	111	57	6	int:SPRY1
Interaction	KRTAP12-1 interactions	KRTAP4-5 KRTAP12-2 KRTAP12-1 KRTAP11-1 KRTAP10-7	9.38e-07	63	57	5	int:KRTAP12-1
Interaction	KRTAP5-4 interactions	KRTAP4-5 KRTAP4-12 KRTAP4-11 KRTAP11-1 KRTAP10-7	9.38e-07	63	57	5	int:KRTAP5-4
Interaction	KRTAP6-2 interactions	KRTAP4-12 KRTAP12-2 KRTAP12-1 KRTAP4-11 KPRP KRTAP11-1 KRTAP12-4	9.46e-07	187	57	7	int:KRTAP6-2
Interaction	ZNF696 interactions	KRTAP4-12 KRTAP12-2 FST KRTAP10-7 SHISA3	1.38e-06	68	57	5	int:ZNF696
Interaction	LCE1D interactions	KRTAP4-5 KRTAP4-12 KRTAP4-11 KRTAP10-11 KRTAP10-7	1.59e-06	70	57	5	int:LCE1D
Interaction	LCE2D interactions	KRTAP4-5 KRTAP4-12 KRTAP4-11 KRTAP10-11 KRTAP10-7	2.10e-06	74	57	5	int:LCE2D
Interaction	KRTAP15-1 interactions	KRTAP12-2 KRTAP12-1 KRTAP4-11 KPRP KRTAP11-1	3.29e-06	81	57	5	int:KRTAP15-1
Interaction	KRTAP10-1 interactions	KRTAP4-5 KRTAP4-12 KRTAP12-1 KRTAP4-11 KRTAP10-11 KRTAP10-7	4.58e-06	153	57	6	int:KRTAP10-1
Interaction	VASN interactions	JAG2 KRTAP4-5 KRTAP12-2 KRTAP4-11 KRTAP11-1 KRTAP10-7	5.92e-06	160	57	6	int:VASN
Interaction	FAM27E3 interactions	KRTAP4-12 KRTAP12-2 KRTAP10-7	6.01e-06	13	57	3	int:FAM27E3
Interaction	CHRD interactions	CHRDL2 KRTAP4-12 KRTAP12-2 KRTAP12-1 KRTAP10-7	6.85e-06	94	57	5	int:CHRD
Interaction	SHFL interactions	KRTAP4-5 KRTAP4-12 KRTAP4-11 TRIM55 KRTAP10-7	8.00e-06	97	57	5	int:SHFL
Interaction	KRTAP19-2 interactions	KRTAP4-12 KRTAP12-2 KPRP KRTAP12-4	9.37e-06	47	57	4	int:KRTAP19-2
Interaction	GNE interactions	KRTAP4-12 KRTAP4-11 KPRP KRTAP11-1 KRTAP10-7	1.12e-05	104	57	5	int:GNE
Interaction	DHRS1 interactions	KRTAP12-2 KRTAP12-1 KRTAP4-11 KRTAP11-1	1.30e-05	51	57	4	int:DHRS1
Interaction	KRTAP1-3 interactions	KRTAP4-5 KRTAP4-12 KRTAP12-1 KRTAP4-11 KPRP KRTAP10-11	1.32e-05	184	57	6	int:KRTAP1-3
Interaction	LELP1 interactions	KRTAP4-5 KRTAP4-12 KRTAP4-11	1.42e-05	17	57	3	int:LELP1
Interaction	GLRX3 interactions	KRTAP4-7 KRTAP4-5 KRTAP4-12 KRTAP4-11 FGB KRTAP10-11	1.63e-05	191	57	6	int:GLRX3
Interaction	NUFIP2 interactions	KRTAP4-5 KRTAP4-12 KRTAP4-11 TRIM55 KPRP KRTAP11-1 KRTAP10-11 KRTAP10-7	2.14e-05	417	57	8	int:NUFIP2
Interaction	MGAT5B interactions	KRTAP12-2 KRTAP12-1 RTN4R KPRP KRTAP12-4	2.25e-05	120	57	5	int:MGAT5B
Interaction	MEOX2 interactions	KRTAP4-7 KRTAP4-5 KRTAP4-12 KRTAP12-2 KRTAP12-1 KRTAP4-11 KPRP KRTAP10-11 KRTAP12-4 SHISA3	2.28e-05	697	57	10	int:MEOX2
Interaction	KRTAP5-2 interactions	KRTAP4-5 KRTAP4-11 KRTAP10-11 KRTAP10-7	2.84e-05	62	57	4	int:KRTAP5-2
Interaction	KRTAP10-11 interactions	KRTAP4-12 KRTAP4-11 KRTAP10-11 KRTAP10-7	3.22e-05	64	57	4	int:KRTAP10-11
Interaction	PHLDA1 interactions	KRTAP4-12 KRTAP12-2 KPRP KRTAP10-7	3.64e-05	66	57	4	int:PHLDA1
Interaction	PRKAB2 interactions	RNF144B KRTAP4-5 KRTAP4-12 TRIM55 KRTAP10-11 KRTAP10-7	5.09e-05	234	57	6	int:PRKAB2
Interaction	KRTAP10-9 interactions	KRTAP4-5 KRTAP4-12 KRTAP12-1 KRTAP4-11 KRTAP10-11 KRTAP10-7	5.99e-05	241	57	6	int:KRTAP10-9
Interaction	KRTAP4-5 interactions	KRTAP4-5 KRTAP12-1 KPRP KRTAP10-7	6.34e-05	76	57	4	int:KRTAP4-5
Interaction	KRTAP3-2 interactions	KRTAP4-12 KRTAP12-2 KRTAP12-1 KPRP	7.38e-05	79	57	4	int:KRTAP3-2
Interaction	ZNF837 interactions	KRTAP4-5 KRTAP4-12 KRTAP4-11 KRTAP10-7	7.38e-05	79	57	4	int:ZNF837
Interaction	IQUB interactions	KRTAP12-2 TRIM55 KRTAP10-7 KRTAP12-4	7.75e-05	80	57	4	int:IQUB
Interaction	KRTAP4-11 interactions	KRTAP4-11 KRTAP11-1 KRTAP10-11 KRTAP10-7	1.34e-04	92	57	4	int:KRTAP4-11
Interaction	CGB1 interactions	CGB1 CGB2	1.64e-04	7	57	2	int:CGB1
Interaction	KRTAP10-7 interactions	KRTAP4-5 KRTAP4-12 KRTAP12-1 KRTAP4-11 KRTAP10-11 KRTAP10-7	1.75e-04	293	57	6	int:KRTAP10-7
Interaction	KRTAP13-2 interactions	KRTAP4-5 KRTAP12-2 KPRP KRTAP11-1	1.77e-04	99	57	4	int:KRTAP13-2
Interaction	KRTAP6-1 interactions	KRTAP4-5 KRTAP12-1 KPRP KRTAP11-1	2.06e-04	103	57	4	int:KRTAP6-1
Interaction	VENTX interactions	RNF144B KRTAP12-2 KRTAP11-1 KRTAP12-4	2.14e-04	104	57	4	int:VENTX
Interaction	BEX2 interactions	KRTAP4-12 KRTAP12-2 KRTAP11-1 FST	2.30e-04	106	57	4	int:BEX2
Interaction	KRTAP11-1 interactions	KRTAP12-1 KRTAP4-11 KRTAP11-1 KRTAP12-4	2.48e-04	108	57	4	int:KRTAP11-1
Interaction	ZNF20 interactions	KRTAP4-12 TRIM55 KRTAP10-7	2.62e-04	44	57	3	int:ZNF20
Interaction	ZNF581 interactions	KRTAP4-12 KRTAP12-2 TRIM55 KRTAP10-7	2.75e-04	111	57	4	int:ZNF581
Interaction	BMP5 interactions	CHRDL2 FST	2.79e-04	9	57	2	int:BMP5
Interaction	PCSK5 interactions	KRTAP4-12 KRTAP12-2 KRTAP11-1 KRTAP10-7	2.85e-04	112	57	4	int:PCSK5
Interaction	ZIC1 interactions	RNF144B KRTAP12-1 KPRP KRTAP11-1	3.25e-04	116	57	4	int:ZIC1
Interaction	KRTAP1-5 interactions	KRTAP4-5 KRTAP4-11 KPRP	3.39e-04	48	57	3	int:KRTAP1-5
Interaction	KRTAP1-1 interactions	KRTAP4-5 KRTAP4-12 KRTAP12-1 KRTAP4-11 KRTAP10-11	3.83e-04	219	57	5	int:KRTAP1-1
Interaction	POM121L8P interactions	KRTAP12-2 KRTAP10-7	4.25e-04	11	57	2	int:POM121L8P
Interaction	HOXC8 interactions	KRTAP12-1 KPRP KRTAP11-1 KRTAP10-7	4.32e-04	125	57	4	int:HOXC8
Interaction	CBX2 interactions	KRTAP4-12 KRTAP12-2 TRIM55 KRTAP10-7	4.45e-04	126	57	4	int:CBX2
Interaction	KRTAP12-4 interactions	KRTAP12-2 KRTAP11-1 KRTAP12-4	4.55e-04	53	57	3	int:KRTAP12-4
Interaction	NPPC interactions	NPR1 NPR2	5.09e-04	12	57	2	int:NPPC
Interaction	ZFP41 interactions	RAD18 LRP1B KRTAP10-7	5.63e-04	57	57	3	int:ZFP41
Interaction	ADAM12 interactions	KRTAP4-12 KRTAP12-2 FST	5.93e-04	58	57	3	int:ADAM12
Interaction	ZNF408 interactions	KRTAP4-12 KRTAP12-2 LRP1B KRTAP10-7	7.55e-04	145	57	4	int:ZNF408
Interaction	KRTAP12-3 interactions	KRTAP12-1 KPRP KRTAP11-1 KRTAP10-7	7.75e-04	146	57	4	int:KRTAP12-3
Interaction	ZNF625 interactions	KPRP KRTAP10-7	8.06e-04	15	57	2	int:ZNF625
Interaction	NPDC1 interactions	KRTAP4-12 KRTAP12-2 KRTAP10-7	8.27e-04	65	57	3	int:NPDC1
Cytoband	17q21.2	KRTAP9-7 KRTAP4-7 KRTAP4-8 KRTAP4-11 KRTAP4-9 KRTAP16-1 KRT10-AS1	5.75e-12	70	61	7	17q21.2
Cytoband	Ensembl 112 genes in cytogenetic band chr17q21	KRTAP9-7 KRTAP4-7 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP4-11 KRTAP4-6 KRTAP4-9 KRTAP16-1 KRT10-AS1	6.92e-10	473	61	10	chr17q21
Cytoband	21q22.3	KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	2.04e-08	128	61	6	21q22.3
Cytoband	Ensembl 112 genes in cytogenetic band chr21q22	KRTAP13-4 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP11-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	3.87e-08	377	61	8	chr21q22
Cytoband	19q13.32	LHB CGB1 CGB2 CGB3 CGB7	5.26e-08	74	61	5	19q13.32
Cytoband	17q12-q21	KRTAP4-5 KRTAP4-12 KRTAP4-6	1.08e-05	32	61	3	17q12-q21
Cytoband	21q22.1	KRTAP13-4 KRTAP11-1	1.25e-03	39	61	2	21q22.1
Cytoband	10q22.1	TSPAN15 UNC5B	1.73e-03	46	61	2	10q22.1
GeneFamily	Keratin associated proteins	KRTAP9-7 KRTAP4-7 KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP4-6 KRTAP4-9 KRTAP11-1 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	1.18e-26	109	47	17	619
GeneFamily	Guanylate cyclase receptors	NPR1 NPR2	1.38e-04	7	47	2	343
GeneFamily	CD molecules\|Mucins	MUC5B MUC5AC	1.35e-03	21	47	2	648
GeneFamily	CD molecules\|Tumor necrosis factor receptor superfamily\|Death inducing signaling complex	TNFRSF8 LTBR	2.57e-03	29	47	2	782
GeneFamily	Endogenous ligands	LHB CGB3 FGB CCL23	3.30e-03	237	47	4	542
GeneFamily	CD molecules\|Tetraspanins	TSPAN15 TSPAN33	3.32e-03	33	47	2	768
GeneFamily	Ring finger proteins	RNF144B RAD18 TRIM55 BRAP	5.59e-03	275	47	4	58
Coexpression	LIN_NPAS4_TARGETS_DN	KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP4-11 KRTAP4-6	1.14e-06	79	61	5	MM1239
Coexpression	WANG_LSD1_TARGETS_DN	LHB CGB1 CGB2 CGB7	3.68e-06	45	61	4	MM740
Coexpression	HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_DN	LHB CGB1 CGB2 CGB7	9.56e-06	57	61	4	MM807
Coexpression	HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_UP	LHB CGB1 CGB2 CGB7	3.50e-05	79	61	4	MM804
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	KRTAP9-7 KRTAP4-5 KRTAP4-12 KRTAP4-8 KRTAP12-2 KRTAP10-10 KRTAP12-1 KRTAP4-11 KRTAP4-6 KRTAP4-9 KRTAP11-1 KRTAP16-1 KRTAP10-11 KRTAP10-7 KRTAP12-4	1.38e-24	146	61	15	522c32103c24fc26836bb5b642083904682d9292
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma-10\|TCGA-Bladder / Sample_Type by Project: Shred V9	KRTAP9-7 KRTAP13-4 KRTAP4-5 KRTAP4-12 KRTAP4-11 KRTAP4-6 KRTAP11-1	5.18e-10	129	61	7	6a201c6344a015e5cf2f79ccf397fd7ad66b6768
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRTAP4-7 KRTAP4-8 UNC5B KPRP KRTAP4-6 KRTAP4-9	2.89e-08	133	61	6	f7d0763b5eec2db33044d6850fd57462494038c1
ToppCell	facs-MAT-Fat-24m-Endothelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 PLEK2 TSPAN15 RNF144B GJA4 UNC5B	2.63e-07	193	61	6	ba9a47e2dc01efa6d2a99b1631d4951fac2648d4
ToppCell	facs-MAT-Fat-24m-Endothelial-endothelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 PLEK2 TSPAN15 RNF144B GJA4 UNC5B	2.63e-07	193	61	6	724bb613fa434add5b1c5586b629328f819fbdfe
ToppCell	facs-MAT-Fat-24m-Endothelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 PLEK2 TSPAN15 RNF144B GJA4 UNC5B	2.63e-07	193	61	6	737e540c72a3cfe8dbd4c0f139f7d729a166793a
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma-6\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	KRTAP9-7 CGB1 TRIM55 KRTAP4-6 KRTAP10-7	4.25e-07	110	61	5	ebf871bf29796caf25dd83a587774efe7f7c79ec
ToppCell	VE-matDC-\|VE / Condition, Cell_class and T cell subcluster	TSPAN15 RNF144B GJA4 ANKRD33B TSPAN33	4.94e-06	181	61	5	6252184ef098b911df50be4fe1b5565849a5b6b8
ToppCell	VE-matDC\|VE / Condition, Cell_class and T cell subcluster	TSPAN15 RNF144B GJA4 ANKRD33B TSPAN33	4.94e-06	181	61	5	982fd96ef75bc9ab2c2f4970c01b76ba7a164871
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B GJA4 NPR1	6.26e-06	190	61	5	9a2244c3973aee7270646bf00db7727edb9decc5
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	JAG2 RNF144B GJA4 NPR1 UNC5B	6.42e-06	191	61	5	e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B GJA4 NPR1	6.58e-06	192	61	5	7dbe3117a0f58ff2e838963d49f788a59a4351d7
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B GJA4 NPR1	6.75e-06	193	61	5	72d20ee257149b238016b44d183ce3fc24b8f621
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TSPAN15 GJA4 ZAN ANKRD33B TSPAN33	6.75e-06	193	61	5	a2194012dfa0174c6160900625c44e0fd04c50e7
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature1_(0)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B GJA4 NPR1	6.75e-06	193	61	5	2661ad9107ed9231e4afea4442a79051139a31df
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B GJA4 NPR1	6.75e-06	193	61	5	d338a7c0585b69947c37f44aa0381619493e31ea
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TSPAN15 GJA4 ZAN ANKRD33B TSPAN33	6.75e-06	193	61	5	7426a30ed01e5c8376b3e0ebe0f1057cfee88340
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating3_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B GJA4 NPR1	6.75e-06	193	61	5	f7e4a390921780587b9bd084e495e646fa1ec74f
ToppCell	PCW_05-06-Endothelial\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B GJA4 NPR1	6.92e-06	194	61	5	00291c62795a55a7e63b1db10c139d6a3298e55e
ToppCell	PCW_05-06-Endothelial-Endothelial_immature\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B GJA4 NPR1	6.92e-06	194	61	5	9bd25ea57f2da27bd200d1a8bf797fec77d172c7
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B GJA4 NPR1	6.92e-06	194	61	5	eb279e0d922de921343f0ae032a809f837d915b3
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_venous_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B NPR1 CCL23	7.10e-06	195	61	5	ca2cf2c10db1ad17aa0a2e30aa7079a7ad751ea6
ToppCell	PCW_07-8.5-Endothelial\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B GJA4 NPR1	7.10e-06	195	61	5	f2cc94d5e1652203ca38bea57f37d3deec73ef04
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B GJA4 NPR1	7.10e-06	195	61	5	c7abcb674e4a25a5354c4947fffd0d17bc8c1fab
ToppCell	PCW_07-8.5-Endothelial-Endothelial_cycling\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B GJA4 NPR1	7.10e-06	195	61	5	804b7c44aaaf8ba77e36f377955df261e92f5ff9
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-B_(Artery)\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	JAG2 RNF144B GJA4 TNFRSF8 ANKRD33B	7.28e-06	196	61	5	f540cf17b4405a6dd38d2b6123e6541d0aac889e
ToppCell	LAM-Endothelial-VasEndo-2\|Endothelial / Condition, Lineage and Cell class	JAG2 RNF144B GJA4 CCL23 ADIPOR2	7.64e-06	198	61	5	92bccaec01f1dbb17d5efcba30f7f800f674ca96
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 RNF144B GJA4 NPR1 UNC5B	7.83e-06	199	61	5	9b02acae6325b0ac9642438a4431285ff396e5fe
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma-2\|TCGA-Endometrium / Sample_Type by Project: Shred V9	KRTAP12-2 PIWIL3 KRTAP10-11 KRTAP10-7	1.32e-05	105	61	4	744be8b4255bef3a973db7e4306e52387852e502
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZAN OTOGL KPRP LRP1B	7.20e-05	162	61	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RTN4R FSTL4 ANKRD33B SHISA3	7.38e-05	163	61	4	431221a41d396b09170476179590eaf8a55266d8
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TSPAN15 NPR1 ANKRD33B TSPAN33	7.38e-05	163	61	4	f4fcac0af9967ec34a43c9674aa17b0aa5344cf6
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RTN4R FSTL4 ANKRD33B SHISA3	7.38e-05	163	61	4	1e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FSTL4 FGB DCST1 MUC5AC	9.50e-05	174	61	4	e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FSTL4 FGB DCST1 MUC5AC	9.50e-05	174	61	4	ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 NPR1 UNC5B FGB	9.92e-05	176	61	4	96779273b94345250cf53ba671203345b43d9e00
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	TSPAN15 RNF144B ANKRD33B TSPAN33	1.08e-04	180	61	4	aae85fb3c92a45614616a3ee3a1af5244cc299a7
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	JAG2 RNF144B GJA4 NPR1	1.08e-04	180	61	4	5861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLEK2 GJA4 ALKBH8 UNC5B	1.11e-04	181	61	4	136b0c60680068838d184d32aa99d7bea8718dbc
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JAG2 NPR1 ZAN CCL23	1.13e-04	182	61	4	d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCell	wk_08-11-Mesenchymal-Mesothelial-Late_mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NPR1 RTN4R SLC44A2 ANKRD33B	1.13e-04	182	61	4	f8257c884393f168f605d371e0840cfca8d3657e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN OTOGL MUC5B LRP1B	1.18e-04	184	61	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN OTOGL MUC5B LRP1B	1.18e-04	184	61	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN OTOGL MUC5B LRP1B	1.18e-04	184	61	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating2_(14)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B NPR1	1.23e-04	186	61	4	2cbf1aaff87cd9fba01f814a119fe86e5af82290
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JAG2 GJA4 NPR1 UNC5B	1.25e-04	187	61	4	d9d10ed7c905778a29a0dc3ced3eef02a6b1de5c
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 RNF144B GJA4 NPR1	1.25e-04	187	61	4	106f50ad85a92403037214f0e94702230284837f
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JAG2 GJA4 NPR1 UNC5B	1.25e-04	187	61	4	25efb82afe863a853ecdd781ad89026c993aaa67
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLEK2 GJA4 NPR1 UNC5B	1.25e-04	187	61	4	66ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	JAG2 GJA4 NPR1 UNC5B	1.25e-04	187	61	4	a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 RNF144B GJA4 NPR1	1.25e-04	187	61	4	29b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	JAG2 GJA4 NPR1 UNC5B	1.28e-04	188	61	4	366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JAG2 GJA4 NPR1 UNC5B	1.31e-04	189	61	4	db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCell	PND07-28-samps-Endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	JAG2 GJA4 NPR1 ANKRD33B	1.31e-04	189	61	4	eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_bronchial_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TSPAN15 RNF144B NPR1 CCL23	1.31e-04	189	61	4	4bc3826e0515b3cf2e2ef72a7b2cf9c32ade1812
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	JAG2 GJA4 NPR1 ANKRD33B	1.31e-04	189	61	4	d4a25d59d88325d3b20f4287e9b1160c82961a96
ToppCell	normal_Lymph_Node-Myeloid_cells-Activated_DCs\|normal_Lymph_Node / Location, Cell class and cell subclass	TSPAN15 RNF144B ANKRD33B TSPAN33	1.33e-04	190	61	4	15978ddd37b521343f88b62dad1643077fc22b2b
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLEK2 GJA4 NPR1 UNC5B	1.33e-04	190	61	4	d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 RNF144B GJA4 NPR1	1.33e-04	190	61	4	1307688255a1250fa300edf2c41f1affe31dcc98
ToppCell	droplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 GJA4 NPR1 ANKRD33B	1.33e-04	190	61	4	e64b191f928935484e2c993d7f8af0572a617a3a
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	JAG2 RNF144B GJA4 NPR1	1.33e-04	190	61	4	7ba2be2630183df86de21689289a8620a4cd507e
ToppCell	PCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TSPAN15 RNF144B GJA4 NPR1	1.36e-04	191	61	4	edfd5eeff69b5de19c5df3d899e42acd7e015913
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 RNF144B GJA4 ADIPOR2	1.39e-04	192	61	4	bacbaef1f230051335f4433e55db07a161b96b4c
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	JAG2 RNF144B GJA4 UNC5B	1.39e-04	192	61	4	aedddccacf60e884af044cefba6c64ca10ac97d2
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature2_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B NPR1	1.39e-04	192	61	4	f68e6cbde87678122da1b5c0061904cfb7d04bf5
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLEK2 GJA4 NPR1 UNC5B	1.39e-04	192	61	4	285a9d332a1e07b94f222d4b518dd56928b9e075
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	JAG2 RNF144B GJA4 UNC5B	1.39e-04	192	61	4	389d5e6d0689371bfe1d0b06e92e0e6e5573567b
ToppCell	PCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating2_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B NPR1	1.39e-04	192	61	4	ac3d87aa301d30515c369bd7fc16f33b82173a85
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	RNF144B LRP1B ANKRD33B ADIPOR2	1.39e-04	192	61	4	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 GJA4 NPR1 ANKRD33B	1.41e-04	193	61	4	ff048e7fbab95d7914f3a636f6f014e7115d63d8
ToppCell	droplet-Lung-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSPAN15 GJA4 NPR1 ANKRD33B	1.41e-04	193	61	4	95c9c63bddfed1a84393ccd3578cfe65bc0c1c05
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSPAN15 GJA4 NPR1 ANKRD33B	1.41e-04	193	61	4	1b6317b740cad2439f08b9e9895426d861e7a161
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	JAG2 RNF144B GJA4 NPR1	1.41e-04	193	61	4	4f38aae346ea3b4258744e9dc1e5aeb4fea13d06
ToppCell	droplet-Lung-nan-21m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 GJA4 NPR1 ANKRD33B	1.41e-04	193	61	4	ae35c5757a88b02f8b9f94a0af4c3396ca828cc3
ToppCell	PCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating3_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B NPR1	1.41e-04	193	61	4	72128ece598070f8e752a0691e024e26ab364989
ToppCell	droplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 GJA4 NPR1 ANKRD33B	1.41e-04	193	61	4	ab54c4b8ae17580e2f2bfcdcb1456fe52dedafe9
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSPAN15 GJA4 NPR1 ANKRD33B	1.41e-04	193	61	4	f5861cfa4401b476229a7c61cd64abad79a4bbfc
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	JAG2 RNF144B GJA4 NPR1	1.44e-04	194	61	4	8c88a0ddd61ad900426e312ca4ab13061c0380b8
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TSPAN15 RNF144B GJA4 NPR1	1.44e-04	194	61	4	32ba2cf9b8726bc3c6e9dc24b54d22ff188bb12b
ToppCell	(6)_Endothelial-B_(Artery)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	JAG2 RNF144B GJA4 TNFRSF8	1.44e-04	194	61	4	0cf4e67d4024652794b5bfdd4a71a7d98900b4c8
ToppCell	droplet-Lung-1m-Endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSPAN15 GJA4 NPR1 ANKRD33B	1.44e-04	194	61	4	b1a25e3b36e7b7e558ef95ec22a3bdcbceae821f
ToppCell	PCW_05-06-Endothelial-Endothelial_mature\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	JAG2 RNF144B GJA4 NPR1	1.47e-04	195	61	4	54fde2cfa51ab3a2d48d2426494ca6f0ce77f725
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	JAG2 RNF144B GJA4 UNC5B	1.47e-04	195	61	4	a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCell	11.5-Distal-Endothelial\|Distal / Age, Tissue, Lineage and Cell class	TSPAN15 RNF144B GJA4 NPR1	1.47e-04	195	61	4	efdede0f476883ffddd247fa7bc6449e7932613e
ToppCell	11.5-Distal-Endothelial-Endothelial\|Distal / Age, Tissue, Lineage and Cell class	TSPAN15 RNF144B GJA4 NPR1	1.47e-04	195	61	4	1e9b52b201ab6c78f536609e2afe1d680c71a6e7
ToppCell	PCW_13-14-Endothelial-Endothelial_mature\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	JAG2 RNF144B GJA4 NPR1	1.47e-04	195	61	4	31353269591c9eee84872838e91995d4a035da46
ToppCell	droplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSPAN15 GJA4 NPR1 ANKRD33B	1.50e-04	196	61	4	9e737eaa98fd49972fce64d1d4a4d1f34b9bcb96
ToppCell	15-Distal-Endothelial-Endothelial\|Distal / Age, Tissue, Lineage and Cell class	TSPAN15 RNF144B GJA4 NPR1	1.50e-04	196	61	4	fda2dd3895bf6ae39fcce2050e4878750f5f5b71
ToppCell	15-Distal-Endothelial\|Distal / Age, Tissue, Lineage and Cell class	TSPAN15 RNF144B GJA4 NPR1	1.50e-04	196	61	4	03245aca5cb97fd5c3f8a986efff7131ccd40e34
ToppCell	PCW_13-14-Endothelial\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B NPR1	1.50e-04	196	61	4	7286de29a34e13834cd6347c67a1443897fa4ade
ToppCell	droplet-Lung-30m-Endothelial-capillary_endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSPAN15 GJA4 NPR1 ANKRD33B	1.50e-04	196	61	4	99a7f2e57774884216525897dcd32a289107548b
ToppCell	PCW_13-14-Endothelial-Endothelial_immature\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 RNF144B NPR1	1.50e-04	196	61	4	9ed96085f0acce07bf2f8d4cc212cc50e613be0c
ToppCell	PCW_10-12-Endothelial\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	JAG2 TSPAN15 GJA4 NPR1	1.50e-04	196	61	4	2c60dcf9132ee156f25b349e2ac5313709def4f6
ToppCell	11.5-Airway-Endothelial-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	JAG2 TSPAN15 GJA4 NPR1	1.50e-04	196	61	4	509ddea8d6e1d0b832f69490ab8a736af4ca19a8
ToppCell	11.5-Airway-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	JAG2 TSPAN15 GJA4 NPR1	1.50e-04	196	61	4	e7d55933e23599122e20498548abf5b30fc25c8f
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JAG2 RNF144B GJA4 TNFRSF8	1.53e-04	197	61	4	61b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCell	(4)_Endothelial_cells-(41)_EC-arteriolar\|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	JAG2 GJA4 UNC5B ANKRD33B	1.53e-04	197	61	4	482e3f8926880afed88ed37553ed2b5ed58b8c99
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NPR1 FST LRP1B SVEP1	1.53e-04	197	61	4	17344464fdcc5ba0c03959696b97c195f11e644c
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NPR1 FST LRP1B SVEP1	1.53e-04	197	61	4	3bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NPR1 FST LRP1B SVEP1	1.53e-04	197	61	4	5b8d0d7116b20d8e27541e88ec80c9f1f477e384
Computational	Genes in the cancer module 65.	NPR1 NPR2	2.13e-04	10	24	2	MODULE_65
Computational	Genes in the cancer module 445.	NPR1 NPR2	4.93e-04	15	24	2	MODULE_445
Drug	NO-cAMP	LHB NPR1 CGB1 CGB2 BRAP	1.06e-06	69	60	5	CID006426615
Drug	Factrel	LHB NPR1 CGB1 CGB2 CGB3 CGB7 FST	3.74e-06	246	60	7	CID000036523
Drug	Erythrityl Tetranitrate	NPR1 NPR2	6.83e-06	2	60	2	DB01613
Drug	NSC350854	LHB CGB1 ZAN CGB2 FST	9.71e-06	108	60	5	CID000434448
Drug	Nesiritide	NPR1 NPR2	2.05e-05	3	60	2	DB04899
Drug	CAS 87-33-2	NPR1 NPR2 CGB1 CGB2	4.14e-05	73	60	4	CID000003780
Disease	lutropin subunit beta measurement	LHB CGB3	8.78e-06	3	51	2	EFO_0801773
Disease	chronic fatigue syndrome	KRTAP4-5 KRTAP4-6	4.37e-05	6	51	2	EFO_0004540
Disease	luteinizing hormone measurement	LHB CGB3	1.05e-04	9	51	2	EFO_0007002
Disease	pulmonary fibrosis	MUC5B MUC5AC	1.59e-04	11	51	2	EFO_0009448
Disease	venous thromboembolism, fibrinogen measurement	TSPAN15 SLC44A2 FGB	2.16e-04	67	51	3	EFO_0004286, EFO_0004623
Disease	human Chorionic Gonadotropin measurement	LHB CGB3	2.26e-04	13	51	2	EFO_0008156
Disease	Hypogonadotropic hypogonadism	LHB CGB3	3.03e-04	15	51	2	C0271623
Disease	Primary hypogonadism	LHB CGB3	3.03e-04	15	51	2	C0948896
Disease	Hypogonadism, Isolated Hypogonadotropic	LHB CGB3	3.03e-04	15	51	2	C3489396
Disease	Hypogonadism	LHB CGB3	3.46e-04	16	51	2	C0020619
Disease	Ischemic stroke, venous thromboembolism, stroke, Abnormal thrombosis, deep vein thrombosis, pulmonary embolism	TSPAN15 SLC44A2	3.92e-04	17	51	2	EFO_0000712, EFO_0003827, EFO_0003907, EFO_0004286, HP_0001977, HP_0002140
Disease	venous thromboembolism, plasminogen activator inhibitor 1 measurement	TSPAN15 SLC44A2	6.02e-04	21	51	2	EFO_0004286, EFO_0004792
Disease	myocardial infarction (is_implicated_in)	GJA4 NPR1 FGB	6.79e-04	99	51	3	DOID:5844 (is_implicated_in)
Disease	venous thromboembolism, tissue plasminogen activator measurement	TSPAN15 SLC44A2	7.24e-04	23	51	2	EFO_0004286, EFO_0004791
Disease	Subfertility, Female	LHB ADIPOR2	1.08e-03	28	51	2	C0341869
Disease	Sterility, Postpartum	LHB ADIPOR2	1.08e-03	28	51	2	C0038279
Disease	Female sterility	LHB ADIPOR2	1.08e-03	28	51	2	C0917730
Disease	Female infertility	LHB ADIPOR2	1.08e-03	28	51	2	C0021361
Disease	factor XI measurement, venous thromboembolism	TSPAN15 SLC44A2	1.24e-03	30	51	2	EFO_0004286, EFO_0004694
Disease	factor VIII measurement, venous thromboembolism	TSPAN15 SLC44A2	1.59e-03	34	51	2	EFO_0004286, EFO_0004630
Disease	COVID-19 symptoms measurement	MUC5B MUC5AC	1.68e-03	35	51	2	EFO_0600019
Disease	venous thromboembolism, factor VII measurement	TSPAN15 SLC44A2	1.98e-03	38	51	2	EFO_0004286, EFO_0004619
Disease	Takayasu arteritis	RAD18 LRP1B SVEP1	2.16e-03	148	51	3	EFO_1001857
Disease	attention deficit hyperactivity disorder, conduct disorder	FSTL4 MYRFL	2.19e-03	40	51	2	EFO_0003888, EFO_0004216
Disease	venous thromboembolism, von Willebrand factor measurement	TSPAN15 SLC44A2	2.41e-03	42	51	2	EFO_0004286, EFO_0004629
Disease	spleen volume	LTBR BRAP	2.53e-03	43	51	2	EFO_0600047
Disease	Uveal Melanoma	UNC5B LRP1B	3.81e-03	53	51	2	EFO_1000616
Disease	Hypertensive disease	LHB GJA4 NPR1	4.36e-03	190	51	3	C0020538
Disease	idiopathic pulmonary fibrosis	MUC5B MUC5AC	4.40e-03	57	51	2	EFO_0000768
Disease	congenital heart disease	SLC44A2 LRP1B	4.71e-03	59	51	2	EFO_0005207
Disease	pancreatic ductal carcinoma (is_marker_for)	MUC5B MUC5AC	5.02e-03	61	51	2	DOID:3587 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
DDTTCPVCRYCQTPE	BRAP	296	Q7Z569
SADCCISYTPRSIPC	CCL23	51	P55773
VRQTPCNCSYPLVCD	ALKBH8	336	Q96BT7
CITVNTTICAGYCPT	CGB1	76	A6NKQ9
DPSVTPCCNPYQIAC	ARSG	506	Q96EG1
CIDPPNICIVTEYCP	NPR2	586	P20594
ACTDPPNICILTEYC	NPR1	601	P16066
YSPAVAIVCQTVCPE	ANKRD33B	316	A6NCL7
LCRCPTCPCATFVEY	MUC5B	291	Q9HC84
ELRVLCCEYVPCGPS	MUC5B	1421	Q9HC84
CNPQPCFIYLIVICV	ADIPOR2	241	Q86V24
YKTQCPTCCVTVTEP	RAD18	56	Q9NS91
PYRTWCPVADCQTVC	RNF144B	116	Q7Z419
SCEFPTCEPLTQFVC	LRP1B	961	Q9NZR2
TCVDEINGYRCSCPP	JAG2	841	Q9Y219
CITVNTTICAGYCPT	LHB	46	P01229
CITVNTTICAGYCPT	CGB7	46	P0DN87
EYCRTPCTVSCNIPV	FGB	221	P02675
FCEILPCQETYCCPI	MYRFL	701	Q96LU7
HTTCYRPTCVISSCP	KRTAP4-11	171	Q9BYQ6
YRPTCVISTCPRPLC	KRTAP4-12	181	Q9BQ66
QYSCACNTSRCPAPV	MUC5AC	5341	P98088
NAYCVTCNRICPEPA	FST	186	P19883
RQDCQRVTCPTEYPC	CHRDL2	286	Q6WN34
CPVCITVNTTICAGY	CGB2	41	Q6NT52
CITVNTTICAGYCPT	CGB3	46	P0DN86
CVVCQAPETPESYVC	DCST1	646	Q5T197
ECQCLEACRPSYVPV	FSTL4	86	Q6MZW2
YRPTCVISTCPRPLC	KRTAP4-5	161	Q9BYR2
HTTCYRPTCVISTCP	KRTAP4-6	181	Q9BYQ5
HTTCYRPTCVISTCP	KRTAP4-7	186	Q9BYR0
HTTCYRPACVISTCP	KRTAP4-8	161	Q9BYQ9
HTTCYRPTCVISSCP	KRTAP4-9	186	Q9BYQ8
VCTPVSYVSSPCCRV	KRTAP10-7	56	P60409
SYVSSPCCRVTCEPS	KRTAP10-7	61	P60409
CCVPVCSKSVCYVPV	KRTAP10-10	146	P60014
TVYCKPICCVPVCSR	KRTAP10-11	196	P60412
CEPTACQPTCYRRTS	KRTAP11-1	61	Q8IUC1
CQPTCYRRTSCVSNP	KRTAP11-1	66	Q8IUC1
QSSVCVPVSCRPVVY	KRTAP12-1	51	P59990
QPVQTCFVECAPVCY	KPRP	126	Q5T749
APVCYTETCYVECPV	KPRP	136	Q5T749
QSSLCVPVSCRPVVY	KRTAP12-2	101	P59991
CQPSCTSVLCRPISY	KRTAP12-2	126	P59991
CCQPFCPTLVYRPVT	KRTAP12-4	91	P60329
YRPRTSILCCPCQTT	KRTAP13-4	66	Q3LI77
CQPSSCAPIYCRRTC	KRTAP9-7	101	A8MTY7
PSCSVSNCYQPVCFE	KRTAP16-1	101	A8MUX0
PAVCVSSPCQPTCYV	KRTAP16-1	321	A8MUX0
PTCYVVKRCPSVCPE	KRTAP16-1	331	A8MUX0
CPTPQICVEKCPDRY	SLC44A2	106	Q8IWA5
VCQRAPCPYLVDCFV	GJA4	186	P35212
RYLCTKCPIPSQCVV	PIWIL3	596	Q7Z3Z3
EVIATPCYTCVCRRG	OTOGL	921	Q3ZCN5
EYQPCVRPCEARTCL	OTOGL	1811	Q3ZCN5
CVCYNEPKVTTSCPQ	RTN4R	31	Q9BZR6
YCVICCRRIGTSTSP	SERAC1	6	Q96JX3
VAIYCCTCLRPKEPS	SHISA3	116	A0PJX4
SCLPCRCSTPVIEYG	SVEP1	3001	Q4LDE5
DNPSRERCSVPYSCC	TSPAN33	176	Q86UF1
CTITCPCLEYENRPL	PLEK2	56	Q9NYT0
RINIYCLNCEVPTCS	TRIM55	131	Q9BYV6
PLACGVPYTCCIRNT	TSPAN15	176	O95858
SCARCVPYPICAAET	TNFRSF8	296	P28908
GCVPSLCCSSYVPSV	KRT10-AS1	11	Q8N816
TLNTPCYCQLEPRAC	UNC5B	656	Q8IZJ1
RICCSRCPPGTYVSA	LTBR	56	P36941
LRIICVCAEDYCPTP	VPS9D1	536	Q9Y2B5
TERCPPNARYESCAC	ZAN	1041	Q9Y493