Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transporter activity	MPV17 SLC39A1 SLC10A4 TMEM175 ABCC9 GRIK1 RYR3 SLC32A1 SLC22A18 SLC39A12 ZACN KCNA2 KCNA3 KCNA4 SLC18A3 SLC15A4 SLCO1A2 SLC27A1 KCNK15 LRP2 TMEM41B SLC23A3	4.38e-06	1289	116	22	GO:0005215
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC39A1 SLC10A4 TMEM175 ABCC9 GRIK1 RYR3 SLC32A1 SLC39A12 ZACN KCNA2 KCNA3 KCNA4 SLC18A3 SLC15A4 KCNK15	7.05e-06	664	116	15	GO:0008324
GeneOntologyMolecularFunction	potassium channel activity	TMEM175 ABCC9 GRIK1 KCNA2 KCNA3 KCNA4 KCNK15	9.85e-06	128	116	7	GO:0005267
GeneOntologyMolecularFunction	transmembrane transporter activity	MPV17 SLC39A1 SLC10A4 TMEM175 ABCC9 GRIK1 RYR3 SLC32A1 SLC22A18 SLC39A12 ZACN KCNA2 KCNA3 KCNA4 SLC18A3 SLC15A4 SLCO1A2 SLC27A1 KCNK15 SLC23A3	1.41e-05	1180	116	20	GO:0022857
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC39A1 SLC10A4 TMEM175 ABCC9 GRIK1 RYR3 SLC32A1 SLC39A12 KCNA2 KCNA3 KCNA4 SLC18A3 SLC15A4 KCNK15	1.66e-05	627	116	14	GO:0022890
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	TMEM175 ABCC9 GRIK1 KCNA2 KCNA3 KCNA4 KCNK15	5.48e-05	167	116	7	GO:0015079
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC39A1 SLC10A4 TMEM175 ABCC9 GRIK1 RYR3 SLC32A1 SLC39A12 ZACN KCNA2 KCNA3 KCNA4 SLC18A3 SLC15A4 KCNK15	5.56e-05	793	116	15	GO:0015075
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC39A1 SLC10A4 TMEM175 ABCC9 GRIK1 RYR3 SLC39A12 KCNA2 KCNA3 KCNA4 KCNK15	8.48e-05	465	116	11	GO:0046873
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC39A1 SLC10A4 TMEM175 ABCC9 GRIK1 RYR3 SLC32A1 SLC39A12 KCNA2 KCNA3 KCNA4 SLC18A3 SLC15A4 KCNK15	1.29e-04	758	116	14	GO:0015318
GeneOntologyMolecularFunction	monoatomic cation channel activity	TMEM175 ABCC9 GRIK1 RYR3 ZACN KCNA2 KCNA3 KCNA4 KCNK15	1.78e-04	343	116	9	GO:0005261
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC10A4 GRIK1 SLC32A1 SLC22A18 SLC39A12 SLC15A4 SLCO1A2 SLC27A1	3.16e-04	293	116	8	GO:0008514
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	ABCC9 KCNA2 KCNA3 KCNA4 KCNK15	3.23e-04	102	116	5	GO:0005249
GeneOntologyMolecularFunction	hormone binding	AMHR2 PDE3A DRD4 EGFR LRP2	3.38e-04	103	116	5	GO:0042562
GeneOntologyMolecularFunction	outward rectifier potassium channel activity	KCNA2 KCNA3 KCNK15	5.05e-04	27	116	3	GO:0015271
GeneOntologyMolecularFunction	delayed rectifier potassium channel activity	KCNA2 KCNA3 KCNA4	5.63e-04	28	116	3	GO:0005251
GeneOntologyMolecularFunction	gated channel activity	ABCC9 GRIK1 RYR3 ZACN KCNA2 KCNA3 KCNA4 KCNK15	7.48e-04	334	116	8	GO:0022836
GeneOntologyMolecularFunction	acetylcholine receptor inhibitor activity	LY6G6D LY6H	9.16e-04	8	116	2	GO:0030550
GeneOntologyMolecularFunction	channel activity	MPV17 TMEM175 ABCC9 GRIK1 RYR3 ZACN KCNA2 KCNA3 KCNA4 KCNK15	9.80e-04	525	116	10	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	MPV17 TMEM175 ABCC9 GRIK1 RYR3 ZACN KCNA2 KCNA3 KCNA4 KCNK15	9.94e-04	526	116	10	GO:0022803
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC10A4 GRIK1 SLC32A1 SLC15A4 SLCO1A2 SLC27A1	1.33e-03	207	116	6	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC10A4 GRIK1 SLC32A1 SLC15A4 SLCO1A2 SLC27A1	1.36e-03	208	116	6	GO:0005342
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC32A1 SLC18A3 SLC15A4 SLCO1A2	1.40e-03	83	116	4	GO:0015101
GeneOntologyMolecularFunction	monoatomic ion channel activity	TMEM175 ABCC9 GRIK1 RYR3 ZACN KCNA2 KCNA3 KCNA4 KCNK15	1.44e-03	459	116	9	GO:0005216
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC10A4 SLC32A1 SLC22A18 SLC39A12 SLC18A3 SLC15A4 SLCO1A2	1.73e-03	296	116	7	GO:0015291
GeneOntologyMolecularFunction	symporter activity	SLC10A4 SLC32A1 SLC22A18 SLC39A12 SLC15A4	1.84e-03	150	116	5	GO:0015293
GeneOntologyMolecularFunction	monocarboxylic acid transmembrane transporter activity	SLC10A4 SLC32A1 SLCO1A2 SLC27A1	1.88e-03	90	116	4	GO:0008028
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	ABCC9 KCNA2 KCNA3 KCNA4 KCNK15	1.95e-03	152	116	5	GO:0022843
GeneOntologyBiologicalProcess	monoatomic ion transport	CYBB DRD4 SLC39A1 SLC10A4 TMEM175 ABCC9 GRIK1 RYR3 SLC32A1 SLC22A18 SLC39A12 ZACN KCNA2 KCNA3 KCNA4 SLC18A3 SLC15A4 SLCO1A2 KCNK15 LRP2 PLP1	2.78e-05	1374	117	21	GO:0006811
GeneOntologyBiologicalProcess	neurotransmitter loading into synaptic vesicle	SLC10A4 SLC32A1 SLC18A3	2.84e-05	11	117	3	GO:0098700
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	DRD4 SLC39A1 TMEM175 ABCC9 GRIK1 RYR3 SLC32A1 SLC39A12 ZACN KCNA2 KCNA3 KCNA4 SLC18A3 SLC15A4 KCNK15 PLP1	8.37e-05	942	117	16	GO:0098655
GeneOntologyBiologicalProcess	monoatomic cation transport	DRD4 SLC39A1 SLC10A4 TMEM175 ABCC9 GRIK1 RYR3 SLC32A1 SLC39A12 ZACN KCNA2 KCNA3 KCNA4 SLC18A3 SLC15A4 KCNK15 LRP2 PLP1	8.96e-05	1157	117	18	GO:0006812
GeneOntologyBiologicalProcess	negative regulation of monocyte activation	FN1 CD33	9.54e-05	3	117	2	GO:0150102
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization involved in establishment of planar polarity	BRSK2 BRSK1	9.54e-05	3	117	2	GO:0090176
GeneOntologyCellularComponent	specific granule	CYBB ILF2 HGSNAT SLC15A4 CD33 NFKB1 ELANE ALDH3B1	3.33e-06	160	117	8	GO:0042581
GeneOntologyCellularComponent	specific granule membrane	CYBB HGSNAT SLC15A4 CD33 ALDH3B1	1.60e-04	91	117	5	GO:0035579
GeneOntologyCellularComponent	presynaptic membrane	DRD4 GRIK1 KCNA2 KCNA3 KCNA4 TENM3 CDH10 GABBR1	1.68e-04	277	117	8	GO:0042734
GeneOntologyCellularComponent	secretory vesicle	DPP7 CYBB SELENOP ILF2 FN1 SLC10A4 HGSNAT ABCC9 DCST2 SLC32A1 SLC18A3 SLC15A4 CD33 NFKB1 ELANE ALDH3B1 BRSK1 GABBR1	1.92e-04	1246	117	18	GO:0099503
GeneOntologyCellularComponent	potassium channel complex	ABCC9 GRIK1 KCNA2 KCNA3 KCNA4	2.98e-04	104	117	5	GO:0034705
GeneOntologyCellularComponent	plasma membrane protein complex	CYBB ABCC9 GRIK1 KCNA2 KCNA3 KCNA4 EGFR SLC18A3 C8B PLP1 CDH10 IL6R GABBR1	4.54e-04	785	117	13	GO:0098797
GeneOntologyCellularComponent	distal axon	DRD4 BRSK2 GRIK1 SLC32A1 KCNA2 KCNA3 SLC18A3 LRP2 BRSK1	7.67e-04	435	117	9	GO:0150034
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	CYBB TMEM201 SLC39A1 YIPF7 PIGG RYR3 KCNA2 STS EGFR FRRS1L SLC27A1 CYP26C1 CYP2U1 LRBA TMEM41B GABBR1 NOTCH4	9.00e-04	1299	117	17	GO:0098827
GeneOntologyCellularComponent	axon terminus	DRD4 GRIK1 SLC32A1 KCNA2 KCNA3 SLC18A3	1.19e-03	210	117	6	GO:0043679
GeneOntologyCellularComponent	monoatomic ion channel complex	CYBB ABCC9 GRIK1 RYR3 KCNA2 KCNA3 KCNA4 KCNK15	1.31e-03	378	117	8	GO:0034702
GeneOntologyCellularComponent	cell surface	WNT7A CR2 HCST GSR SLC32A1 KCNA4 LY6G6D EGFR CD33 LRP2 ELANE LY6H IL6R NOTCH4 MSLN	1.35e-03	1111	117	15	GO:0009986
GeneOntologyCellularComponent	presynapse	DRD4 WNT7A SLC10A4 GRIK1 SLC32A1 KCNA2 KCNA3 KCNA4 TENM3 SLC18A3 BRSK1 CDH10 GABBR1	1.38e-03	886	117	13	GO:0098793
GeneOntologyCellularComponent	neuron projection terminus	DRD4 GRIK1 SLC32A1 KCNA2 KCNA3 SLC18A3	2.01e-03	233	117	6	GO:0044306
GeneOntologyCellularComponent	cation channel complex	ABCC9 GRIK1 RYR3 KCNA2 KCNA3 KCNA4	2.10e-03	235	117	6	GO:0034703
GeneOntologyCellularComponent	endoplasmic reticulum membrane	CYBB SLC39A1 YIPF7 PIGG RYR3 KCNA2 STS EGFR FRRS1L SLC27A1 CYP26C1 CYP2U1 LRBA TMEM41B GABBR1 NOTCH4	2.28e-03	1293	117	16	GO:0005789
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	CYBB WNT7A SLC10A4 TMEM175 HGSNAT DCST2 ANKRD27 FZD7 SLC32A1 EGFR GPR62 SLC18A3 SLC15A4 CD33 LRP2 ALDH3B1	2.54e-03	1307	117	16	GO:0030659
GeneOntologyCellularComponent	vesicle lumen	DPP7 SELENOP ILF2 FN1 EGFR NFKB1 ELANE	2.67e-03	332	117	7	GO:0031983
GeneOntologyCellularComponent	transmembrane transporter complex	CYBB ABCC9 GRIK1 RYR3 ZACN KCNA2 KCNA3 KCNA4 KCNK15	2.72e-03	523	117	9	GO:1902495
GeneOntologyCellularComponent	vesicle membrane	CYBB WNT7A SLC10A4 TMEM175 HGSNAT DCST2 ANKRD27 FZD7 SLC32A1 EGFR GPR62 SLC18A3 SLC15A4 CD33 LRP2 ALDH3B1	2.91e-03	1325	117	16	GO:0012506
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	CYBB SLC39A1 YIPF7 PIGG RYR3 KCNA2 STS EGFR FRRS1L SLC27A1 CYP26C1 CYP2U1 LRBA TMEM41B GABBR1 NOTCH4	2.95e-03	1327	117	16	GO:0042175
Domain	K_chnl_volt-dep_Kv1	KCNA2 KCNA3 KCNA4	1.31e-05	8	117	3	IPR003972
Pubmed	Subunit composition of Kv1 channels in human CNS.	KCNA2 KCNA3 KCNA4	3.99e-07	5	120	3	10428084
Pubmed	Differential K+ channel clustering activity of PSD-95 and SAP97, two related membrane-associated putative guanylate kinases.	KCNA2 KCNA3 KCNA4	7.95e-07	6	120	3	8938729
Pubmed	Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly.	KCNA2 KCNA3 KCNA4	7.95e-07	6	120	3	14686897
Pubmed	Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development.	SLC10A4 SLC32A1 SLC18A3 PAPPA	9.40e-07	22	120	4	36549270
Pubmed	Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases.	KCNA2 KCNA3 KCNA4	1.39e-06	7	120	3	7477295
Pubmed	N-terminal PDZ-binding domain in Kv1 potassium channels.	KCNA2 KCNA3 KCNA4	2.22e-06	8	120	3	12435606
Pubmed	Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells.	KCNA2 KCNA3 KCNA4	4.72e-06	10	120	3	1383027
Pubmed	The ANK repeats of Notch-4/Int3 activate NF-κB canonical pathway in the absence of Rbpj and causes mammary tumorigenesis.	NFKB1 NOTCH4	1.18e-05	2	120	2	29057904
Pubmed	miR-7/EGFR/MEGF9 axis regulates cartilage degradation in osteoarthritis via PI3K/AKT/mTOR signaling pathway.	MEGF9 EGFR	1.18e-05	2	120	2	34629037
Pubmed	Resistance to irinotecan (CPT-11) activates epidermal growth factor receptor/nuclear factor kappa B and increases cellular metastasis and autophagy in LoVo colon cancer cells.	EGFR NFKB1	1.18e-05	2	120	2	24726344
Pubmed	Interaction between epidermal growth factor receptor and interleukin-6 receptor in NSCLC progression.	EGFR IL6R	1.18e-05	2	120	2	30132982
Pubmed	Targeting a unique EGFR epitope with monoclonal antibody 806 activates NF-kappaB and initiates tumour vascular normalization.	EGFR NFKB1	1.18e-05	2	120	2	19432811
Pubmed	Activation of epidermal growth factor receptor is required for NTHi-induced NF-κB-dependent inflammation.	EGFR NFKB1	1.18e-05	2	120	2	22132240
Pubmed	Degradation of EGFR on lung epithelial cells by neutrophil elastase contributes to the aggravation of pneumococcal pneumonia.	EGFR ELANE	1.18e-05	2	120	2	37119853
Pubmed	Inhibition of nuclear factor-kappaB by hyaluronan in rheumatoid chondrocytes stimulated with COOH-terminal heparin-binding fibronectin fragment.	FN1 NFKB1	1.18e-05	2	120	2	17929131
Pubmed	Epstein-Barr virus latent membrane protein 1 modulates distinctive NF- kappaB pathways through C-terminus-activating region 1 to regulate epidermal growth factor receptor expression.	EGFR NFKB1	1.18e-05	2	120	2	20410275
Pubmed	Expression and chromosomal localization of a lymphocyte K+ channel gene.	KCNA2 KCNA3	1.18e-05	2	120	2	2251283
Pubmed	Steroid sulfatase in the human MG-63 preosteoblastic cell line: Antagonistic regulation by glucocorticoids and NFκB.	STS NFKB1	1.18e-05	2	120	2	26631368
Pubmed	ADAM12 promotes gemcitabine resistance by activating EGFR signaling pathway and induces EMT in bladder cancer.	ADAM12 EGFR	1.18e-05	2	120	2	36512304
Pubmed	NF-κB and EGFR participate in S1PR3-mediated human renal cell carcinomas progression.	EGFR NFKB1	1.18e-05	2	120	2	35346818
Pubmed	Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.	POLR2A EGFR	1.18e-05	2	120	2	27587583
Pubmed	SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release.	BRSK2 BRSK1	1.18e-05	2	120	2	16630837
Pubmed	Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway.	EGFR ELANE	1.18e-05	2	120	2	18772136
Pubmed	Expression levels and significance of nuclear factor-κB and epidermal growth factor receptor in hepatolithiasis associated with intrahepatic cholangiocarcinoma.	EGFR NFKB1	1.18e-05	2	120	2	24008372
Pubmed	Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a.	AMHR2 WNT7A	1.18e-05	2	120	2	9790192
Pubmed	Differentiation between dysmyelination and demyelination using magnetic resonance diffusional anisotropy.	GALC PLP1	1.18e-05	2	120	2	7728526
Pubmed	mRNA expression levels and genetic status of genes involved in the EGFR and NF-κB pathways in metastatic non-small-cell lung cancer patients.	EGFR NFKB1	1.18e-05	2	120	2	21951562
Pubmed	An epilepsy-associated KV1.2 charge-transfer-center mutation impairs KV1.2 and KV1.4 trafficking.	KCNA2 KCNA4	1.18e-05	2	120	2	35439054
Pubmed	Fibronectin regulates Wnt7a signaling and satellite cell expansion.	FN1 WNT7A	1.18e-05	2	120	2	23290138
Pubmed	[The relationship between the expression of EGFR NF-kappaB and radiosensitivity in human nasopharyngeal carcinoma].	EGFR NFKB1	1.18e-05	2	120	2	19947250
Pubmed	Transforming growth factor-beta1-mediated activation of NF-kappaB contributes to enhanced ADAM-12 expression in mammary carcinoma cells.	ADAM12 NFKB1	1.18e-05	2	120	2	20688878
Pubmed	Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex.	BRSK2 BRSK1	1.18e-05	2	120	2	30307479
Pubmed	First-trimester maternal serum ADAM12-s and PAPP-A levels are altered in pregnancies conceived after assisted reproduction techniques (ART).	ADAM12 PAPPA	1.18e-05	2	120	2	26697810
Pubmed	Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma.	NFKB1 PAPPA	1.18e-05	2	120	2	26020769
Pubmed	Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation.	BRSK2 BRSK1	1.18e-05	2	120	2	18339622
Pubmed	Characterization of Dmrt3-Derived Neurons Suggest a Role within Locomotor Circuits.	SLC10A4 SLC32A1 SLC18A3	1.42e-05	14	120	3	30578339
Pubmed	First trimester maternal serum PAPP-A, beta-hCG and ADAM12 in prediction of small-for-gestational-age fetuses.	ADAM12 PAPPA	3.53e-05	3	120	2	19003798
Pubmed	Epithelial to mesenchymal transition promotes breast cancer progression via a fibronectin-dependent STAT3 signaling pathway.	FN1 EGFR	3.53e-05	3	120	2	23653350
Pubmed	Circuit specificity in the inhibitory architecture of the VTA regulates cocaine-induced behavior.	SLC32A1 GABBR1	3.53e-05	3	120	2	28114294
Pubmed	Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-Cells.	BRSK2 BRSK1	3.53e-05	3	120	2	22669945
Pubmed	Localization of mRNA for UDP-galactose: ceramide galactosyltransferase in the brain during mouse development.	GALC PLP1	3.53e-05	3	120	2	8911769
Pubmed	Essential role of nuclear factor-kappaB for NADPH oxidase activity in normal and anhidrotic ectodermal dysplasia leukocytes.	CYBB NFKB1	3.53e-05	3	120	2	18523147
Pubmed	Human potassium channel genes: Molecular cloning and functional expression.	KCNA2 KCNA4	3.53e-05	3	120	2	19912772
Pubmed	EGFR expression is linked to osteopontin and Nf-κB signaling in clear cell renal cell carcinoma.	EGFR NFKB1	3.53e-05	3	120	2	22855173
Pubmed	Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid.	EGFR NFKB1	3.53e-05	3	120	2	20074357
Pubmed	Autosomal recessive polycystic kidney disease epithelial cell model reveals multiple basolateral epidermal growth factor receptor sorting pathways.	EGFR BICC1	3.53e-05	3	120	2	20519437
Pubmed	The ablation of the matricellular protein EMILIN2 causes defective vascularization due to impaired EGFR-dependent IL-8 production affecting tumor growth.	EMILIN2 EGFR	3.53e-05	3	120	2	29483644
Pubmed	Induction of epidermal growth factor receptor expression by Epstein-Barr virus latent membrane protein 1 C-terminal-activating region 1 is mediated by NF-kappaB p50 homodimer/Bcl-3 complexes.	EGFR NFKB1	3.53e-05	3	120	2	17881446
Pubmed	Activation of epidermal growth factor receptor gene is involved in transforming growth factor-beta-mediated fibronectin expression in a chondrocyte progenitor cell line.	FN1 EGFR	3.53e-05	3	120	2	20198308
Pubmed	Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR).	EGFR IL6R	3.53e-05	3	120	2	24047696
Pubmed	Carbon monoxide activates NF-kappaB via ROS generation and Akt pathways to protect against cell death of hepatocytes.	CYBB NFKB1	3.53e-05	3	120	2	18497334
Pubmed	A family of three mouse potassium channel genes with intronless coding regions.	KCNA2 KCNA3	3.53e-05	3	120	2	2305265
Pubmed	The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling.	CYBB EGFR	3.53e-05	3	120	2	27650496
Pubmed	Microsatellite polymorphisms in the EGFR, NOTCH4 and E2F4 genes and their association with breast cancer risk.	EGFR NOTCH4	3.53e-05	3	120	2	23015403
Pubmed	Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation.	IL6R MSLN	3.53e-05	3	120	2	21515913
Pubmed	Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K(+) channel function.	KCNA2 KCNA4	3.53e-05	3	120	2	10428758
Pubmed	Perturbation of the Actin Cytoskeleton in Human Hepatoma Cells Influences Interleukin-6 (IL-6) Signaling, but Not Soluble IL-6 Receptor Generation or NF-κB Activation.	NFKB1 IL6R	3.53e-05	3	120	2	34281231
Pubmed	MALT1 is a potential therapeutic target in glioblastoma and plays a crucial role in EGFR-induced NF-κB activation.	EGFR NFKB1	3.53e-05	3	120	2	32452133
Pubmed	Megalin mediates selenoprotein P uptake by kidney proximal tubule epithelial cells.	SELENOP LRP2	3.53e-05	3	120	2	18174160
Pubmed	The secretion of PAPP-A, ADAM12, and PP13 correlates with the size of the placenta for the first month of pregnancy.	ADAM12 PAPPA	3.53e-05	3	120	2	22015022
Pubmed	Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel.	KCNA3 KCNA4	3.53e-05	3	120	2	1986382
Pubmed	NF-κB-driven suppression of FOXO3a contributes to EGFR mutation-independent gefitinib resistance.	EGFR NFKB1	3.53e-05	3	120	2	27091996
Pubmed	Subunit composition determines Kv1 potassium channel surface expression.	KCNA2 KCNA4	3.53e-05	3	120	2	10896669
Pubmed	Fibronectin sensitizes activation of contractility, YAP, and NF-κB in nucleus pulposus cells.	FN1 NFKB1	3.53e-05	3	120	2	37525423
Pubmed	Aberrant fucosylation sustains the NOTCH and EGFR/NF-κB pathways and has a prognostic value in human intrahepatic cholangiocarcinoma.	EGFR NFKB1	3.53e-05	3	120	2	36789652
Pubmed	Human leukocyte elastase induces keratinocyte proliferation by epidermal growth factor receptor activation.	EGFR ELANE	3.53e-05	3	120	2	15245434
Pubmed	Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity.	BRSK2 BRSK1	3.53e-05	3	120	2	20026642
Pubmed	Microtubule stabilization specifies initial neuronal polarization.	BRSK2 BRSK1	3.53e-05	3	120	2	18268107
Pubmed	KCNQ2 channels regulate the population activity of neonatal GABAergic neurons ex vivo.	POLR2A SLC32A1	3.53e-05	3	120	2	37409016
Pubmed	Multiple pathways mediate luteinizing hormone regulation of cGMP signaling in the mouse ovarian follicle.	PDE3A EGFR	3.53e-05	3	120	2	24740605
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	MRI1 SH2D3A PIGG MINPP1 ADAM12 HCST FCSK LRRC25 MEGF9 DMKN SPON2 LYPD3 LGR6	3.74e-05	985	120	13	12975309
Pubmed	Astrocyte-encoded positional cues maintain sensorimotor circuit integrity.	WNT7A SLC32A1 PLP1	4.37e-05	20	120	3	24776795
Pubmed	Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp.	CR2 LY6H MSLN	4.37e-05	20	120	3	30988302
Pubmed	Mechanical load regulates bone growth via periosteal Osteocrin.	FN1 BGLAP LY6H	5.88e-05	22	120	3	34260913
Pubmed	Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas.	EGFR IL6R	7.05e-05	4	120	2	19088723
Pubmed	Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30.	FN1 EGFR	7.05e-05	4	120	2	19342448
Pubmed	Constitutive coupling of a naturally occurring human alpha1a-adrenergic receptor genetic variant to EGFR transactivation pathway.	ADAM12 EGFR	7.05e-05	4	120	2	22089237
Pubmed	Cannabis smoke can be a major risk factor for early-age laryngeal cancer--a molecular signaling-based approach.	EGFR NFKB1	7.05e-05	4	120	2	25736926
Pubmed	Pressure activates epidermal growth factor receptor leading to the induction of iNOS via NFkappaB and STAT3 in human proximal tubule cells.	EGFR NFKB1	7.05e-05	4	120	2	19403642
Pubmed	Ferritin-mediated neutrophil extracellular traps formation and cytokine storm via macrophage scavenger receptor in sepsis-associated lung injury.	CYBB ELANE	7.05e-05	4	120	2	38308264
Pubmed	Twist2 is NFkB-responsive when p120-catenin is inactivated and EGFR is overexpressed in esophageal keratinocytes.	EGFR NFKB1	7.05e-05	4	120	2	33139779
Pubmed	Monocarboxylate transporter-1 is required for cell death in mouse chondrocytic ATDC5 cells exposed to interleukin-1beta via late phase activation of nuclear factor kappaB and expression of phagocyte-type NADPH oxidase.	CYBB NFKB1	7.05e-05	4	120	2	21372137
Pubmed	KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.	KCNA2 KCNA3	7.05e-05	4	120	2	12944270
Pubmed	Ferritin triggers neutrophil extracellular trap-mediated cytokine storm through Msr1 contributing to adult-onset Still's disease pathogenesis.	CYBB ELANE	7.05e-05	4	120	2	36357401
Pubmed	Maternal-fetal transfer of selenium in the mouse.	SELENOP LRP2	7.05e-05	4	120	2	23651543
Pubmed	MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation.	KCNA2 NFKB1	7.05e-05	4	120	2	17576778
Pubmed	CXCR2-driven ovarian cancer progression involves upregulation of proinflammatory chemokines by potentiating NF-κB activation via EGFR-transactivated Akt signaling.	EGFR NFKB1	7.05e-05	4	120	2	24376747
Pubmed	Identification of four novel human G protein-coupled receptors expressed in the brain.	C5AR2 GPR62	7.05e-05	4	120	2	11165367
Pubmed	Tuberous sclerosis complex proteins control axon formation.	BRSK2 BRSK1	7.05e-05	4	120	2	18794346
Pubmed	Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer.	EGFR NFKB1	7.05e-05	4	120	2	23455325
Pubmed	TRIM21 deficiency protects against atrial inflammation and remodeling post myocardial infarction by attenuating oxidative stress.	CYBB NFKB1	7.05e-05	4	120	2	36996623
Pubmed	Sustained induction of NF-kappa B is required for efficient expression of latent human immunodeficiency virus type 1.	POLR2A NFKB1	7.05e-05	4	120	2	17376917
Pubmed	Human Neutrophil Elastase Mediates MUC5AC Hypersecretion via the Tumour Necrosis Factor-α Converting Enzyme-Epidermal Growth Factor Receptor Signalling Pathway in vivo.	EGFR ELANE	7.05e-05	4	120	2	34130299
Pubmed	GAPex-5 mediates ubiquitination, trafficking, and degradation of epidermal growth factor receptor.	GAPVD1 EGFR	7.05e-05	4	120	2	17545148
Pubmed	Lipid rafts and caveolin-1 coordinate interleukin-1beta (IL-1beta)-dependent activation of NFkappaB by controlling endocytosis of Nox2 and IL-1beta receptor 1 from the plasma membrane.	CYBB NFKB1	7.05e-05	4	120	2	19801678
Pubmed	Sepp1(UF) forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1.	SELENOP LRP2	7.05e-05	4	120	2	24434121
Pubmed	Wnt7a-Fzd7 signalling directly activates the Akt/mTOR anabolic growth pathway in skeletal muscle.	WNT7A FZD7	7.05e-05	4	120	2	22179044
Pubmed	Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength.	WNT7A FZD7	7.05e-05	4	120	2	24711502
Pubmed	Selenoprotein P and apolipoprotein E receptor-2 interact at the blood-brain barrier and also within the brain to maintain an essential selenium pool that protects against neurodegeneration.	SELENOP LRP2	7.05e-05	4	120	2	24760755
Pubmed	NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation.	POLR2A NFKB1	7.05e-05	4	120	2	16319923
Cytoband	11p15.5	DRD4 BRSK2 PIDD1 SLC22A18 LRRC56	1.55e-05	118	120	5	11p15.5
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	CCNP C5AR2 ANKRD27 HCST DMKN WDR87 CD33 NTN5 LYPD3 BRSK1 SERTAD1	3.05e-04	1192	120	11	chr19q13
Cytoband	12p12	PDE3A SLCO1A2	5.19e-04	13	120	2	12p12
Cytoband	12q24.32	TMEM132C SLC15A4	5.19e-04	13	120	2	12q24.32
Cytoband	4p16.3	TMEM175 PIGG SPON2	1.47e-03	85	120	3	4p16.3
Cytoband	Xq22	DRP2 PLP1	1.51e-03	22	120	2	Xq22
GeneFamily	Solute carriers	SLC39A1 SLC10A4 SLC32A1 SLC22A18 SLC39A12 SLC18A3 SLC15A4 SLCO1A2 SLC27A1 SLC23A3	9.33e-06	395	80	10	752
GeneFamily	CD molecules\|Complement system\|LY6/PLAUR domain containing	LY6G6D LYPD3 LY6H	4.52e-04	34	80	3	1226
GeneFamily	Potassium voltage-gated channels	KCNA2 KCNA3 KCNA4	7.32e-04	40	80	3	274
GeneFamily	VPS9 domain containing	GAPVD1 ANKRD27	8.50e-04	10	80	2	928
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CR2 PAPPA GABBR1	2.06e-03	57	80	3	1179
Coexpression	BENPORATH_ES_WITH_H3K27ME3	DRD4 WNT7A SLC10A4 GRIK1 CR2 ANKRD27 RYR3 SORCS1 SLC32A1 ZACN KCNA3 GPR62 SPON2 CYP26C1 LRP2 PAPPA LRBA LY6H BARX1 HS3ST3B1 PLP1	2.90e-08	1115	119	21	M10371
Coexpression	BENPORATH_SUZ12_TARGETS	WNT7A SLC10A4 GRIK1 ADAM12 ANKRD27 RYR3 SORCS1 SLC32A1 KLHDC1 KCNA3 SLC18A3 SPON2 CYP26C1 LRP2 PAPPA BARX1 HS3ST3B1	4.45e-06	1035	119	17	M9898
Coexpression	BENPORATH_PRC2_TARGETS	WNT7A SLC10A4 GRIK1 ANKRD27 RYR3 SORCS1 SLC32A1 KCNA3 CYP26C1 LRP2 PAPPA BARX1 HS3ST3B1	8.38e-06	650	119	13	M8448
Coexpression	DURAND_STROMA_S_UP	SELENOP ADAM12 CABLES1 KCNA4 SPON2 PAPPA LY6H NOTCH4 NOVA1	1.07e-05	304	119	9	MM1083
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN	AMHR2 WNT7A ABCC9 RYR3 CABLES1 TMEM132C KCNA4 SPON2 PAPPA CDH10	1.88e-05	411	119	10	M1351
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN	AMHR2 WNT7A ABCC9 RYR3 CABLES1 TMEM132C KCNA4 SPON2 PAPPA CDH10	2.08e-05	416	119	10	MM1002
Coexpression	BENPORATH_EED_TARGETS	DRD4 WNT7A SLC10A4 GRIK1 ANKRD27 RYR3 SORCS1 SLC32A1 KCNA3 EGFR SLC18A3 CYP26C1 LRP2 PAPPA BARX1 HS3ST3B1	2.44e-05	1059	119	16	M7617
Coexpression	DELACROIX_RAR_BOUND_ES	FN1 PIDD1 TMEM127 GSR BRSK1 HS3ST3B1 VARS1 GABBR1 NOTCH4 MSLN	5.32e-05	465	119	10	M2466
Coexpression	DURAND_STROMA_S_UP	SELENOP ADAM12 CABLES1 KCNA4 SPON2 PAPPA NOTCH4 NOVA1	7.01e-05	300	119	8	M2581
Coexpression	DELACROIX_RAR_BOUND_ES	FN1 PIDD1 TMEM127 GSR BRSK1 HS3ST3B1 VARS1 GABBR1 NOTCH4 MSLN	8.64e-05	493	119	10	MM1079
Coexpression	MANNE_COVID19_ICU_VS_HEALTHY_DONOR_PLATELETS_DN	KIF26A ADAM12 CABLES1 SLC18A3 PAPPA NANOS1	8.94e-05	159	119	6	M38979
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_1000	DRD4 DRP2 SLC10A4 BRSK2 LANCL1 ABCC9 GRIK1 ADAM12 RYR3 SORCS1 TMEM132C EGFR FRRS1L HS3ST3B1 PLP1 CDH10	1.38e-05	827	118	16	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000
CoexpressionAtlas	Myeloid Cells, Mo.6C-II-.BM, B220neg CD3neg CD115+ Ly-6C/Glo CD43+, Bone marrow, avg-3	CYBB FN1 HGSNAT EMILIN2 GSR FZD7 LRRC25 SLC15A4 ELANE ALDH3B1 IL6R	1.79e-05	409	118	11	GSM854332_500
CoexpressionAtlas	Myeloid Cells, Mo.6C+II-.BM, B220neg CD3neg CD115+ Ly-6C+, Bone marrow, avg-3	CYBB FN1 EMILIN2 LRRC25 ELANE	4.12e-05	69	118	5	GSM854329_100
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#2	SELENOP DRP2 FN1 GRIK1 ADAM12 TMEM132C SLC18A3 SPON2 CYP26C1 LRP2 PAPPA LY6H BARX1 HS3ST3B1 CDH10 BICC1	7.40e-05	951	118	16	Arv_EB-LF_2500_K2
CoexpressionAtlas	Myeloid Cells, Mo.6C-II-.Bl, CD115+ B220- CD43- Ly6C- MHCII-, Blood, avg-3	CYBB HGSNAT EMILIN2 GSR FZD7 LRRC25 MEGF9 SLC15A4 ALDH3B1 IL6R	8.38e-05	402	118	10	GSM605883_500
CoexpressionAtlas	cerebral cortex	DRP2 WNT7A SLC10A4 BRSK2 GRIK1 SORCS1 SLC32A1 SLC39A12 KCNA2 KCNA4 GPR62 SLCO1A2 FRRS1L LY6H BRSK1 PLP1 CDH10 GABBR1 NOVA1 IL9	1.12e-04	1428	118	20	cerebral cortex
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000	FN1 WNT7A BRSK2 GRIK1 ADAM12 TMEM132C KCNA2 SLC18A3 SPON2 FRRS1L CYP26C1 LYPD3 LRP2 PAPPA LY6H CDH10	1.13e-04	986	118	16	PCBC_EB_fibroblast_1000
CoexpressionAtlas	B cells, B.Pl.AA4+220-.BM, CD138+ AA4.1+ CD43- CD45R-, Bone marrow, avg-3	CYBB TICRR FN1 EMILIN2 GSR LRRC25 MEGF9 CD33 ELANE	1.18e-04	339	118	9	GSM777027_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_200	EMILIN2 CABLES1 TMEM132C EGFR HS3ST3B1	1.55e-04	91	118	5	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200_k5
CoexpressionAtlas	Myeloid Cells, MF.Thio5.II-480int.PC, CD115+ MHCII- F480int SiglecF- CD11c+, Peritoneal Cavity, avg-3	DPP7 CYBB SELENOP GALC FN1 EMILIN2 LRRC25 CD33 SLC27A1 ALDH3B1	1.66e-04	437	118	10	GSM605865_500
ToppCell	facs-Lung-nan-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR LRRC25 CD33 ALDH3B1 IL6R	1.97e-08	169	120	8	05b138511039f1255a5f647040b1b9bdf222bd52
ToppCell	facs-Lung-nan-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR LRRC25 CD33 ALDH3B1 IL6R	1.97e-08	169	120	8	bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	AMHR2 SORCS1 DMKN LRP2 PAPPA LY6H IL6R MSLN	5.10e-08	191	120	8	4c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCell	facs-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB FN1 EMILIN2 GSR LRRC25 CD33 ALDH3B1	3.73e-07	168	120	7	ba9ddd403ee6d6af2fe56dffbd419764bfb703e4
ToppCell	facs-Lung-3m-Hematologic-myeloid-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB FN1 EMILIN2 GSR LRRC25 CD33 ALDH3B1	3.73e-07	168	120	7	af4c35c0d3f030cef8397c35fa498a71112bb16b
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB FN1 EMILIN2 GSR LRRC25 ALDH3B1 IL6R	4.37e-07	172	120	7	a53c906539557594ef10368bc29aec4af063fd37
ToppCell	facs-BAT-Fat-3m-Myeloid-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR LRRC25 ALDH3B1 IL6R	4.37e-07	172	120	7	5f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB FN1 EMILIN2 GSR LRRC25 ALDH3B1 IL6R	4.54e-07	173	120	7	9acad7ec70f713fe3db6cef7bbe3b183bf16ae67
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PHGDH KCNA2 TENM3 MEGF9 SLC27A1 PAPPA PLP1	5.93e-07	180	120	7	1e819c5c87704ec6535dfeaae56561895e239d07
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRSK2 ADAM12 PHGDH SORCS1 KCNA2 PAPPA PLP1	6.39e-07	182	120	7	812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FADS6 KCNA2 TENM3 MEGF9 PAPPA LGR6 PLP1	6.39e-07	182	120	7	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM3 DMKN LRP2 PAPPA BARX1 BICC1 MSLN	6.39e-07	182	120	7	9966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCell	droplet-Lung-LUNG-30m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR LRRC25 DMKN ELANE	6.63e-07	183	120	7	f2e993c7fee631a0cc9d0c8f118f6da33a7c2296
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE3A POLR2A EGFR DMKN NFKB1 LYPD3 PLP1	7.13e-07	185	120	7	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CYBB C5AR2 EMILIN2 HCST LRRC25 CD33 IL6R	8.23e-07	189	120	7	911bedfda2ae032bc8f18ee408d16926cda8ccc2
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE3A SLC10A4 GRIK1 SLC32A1 KCNA3 TENM3 EGFR	9.80e-07	194	120	7	4f758718a1233c25c25d99fc1b7b06f906b8b0a2
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CYBB C5AR2 EMILIN2 LRRC25 MEGF9 CD33 ALDH3B1	1.01e-06	195	120	7	580ed65b4152483b642a7e7dbdf00d03588c46f6
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CYBB C5AR2 EMILIN2 LRRC25 MEGF9 CD33 ALDH3B1	1.09e-06	197	120	7	ec46aa307ce5774b4c0fcba64514f2d0cab3c4f9
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_monocytic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CYBB C5AR2 EMILIN2 LRRC25 MEGF9 CD33 ALDH3B1	1.09e-06	197	120	7	b91016249b3585aa3536e96af18e4f1b1d2d5ce4
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CYBB SELENOP C5AR2 EMILIN2 LRRC25 CD33 ALDH3B1	1.16e-06	199	120	7	0f3ce61bbae69f7e333ed8dacf7257645624e163
ToppCell	Control-Fibroblasts-Mesothelial_FB\|Control / group, cell type (main and fine annotations)	CR2 SORCS1 TMEM132C TENM3 WDR87 NOVA1	2.13e-06	139	120	6	e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PDE3A DRD4 WNT7A PHGDH EGFR SLC18A3	2.62e-06	144	120	6	0322fef818a963be00535d5f141f028d43de5c6a
ToppCell	E18.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYBB HCST GSR SLC32A1 CD33 ALDH3B1	2.73e-06	145	120	6	88e463d5396a8fea2b7b1ecf3c9b144e16b35234
ToppCell	E18.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYBB HCST GSR SLC32A1 CD33 ALDH3B1	2.73e-06	145	120	6	911fee7f27694393e348d94470a1a4e890038902
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PDE3A DRD4 WNT7A RYR3 EGFR SLC18A3	2.73e-06	145	120	6	590ba937c741ae67460f303eca88b1cd3ac87f64
ToppCell	PND01-03-samps-Myeloid-Granulocyte\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	CYBB EMILIN2 GSR LRRC25 ELANE ALDH3B1	3.19e-06	149	120	6	7bdb396de8a1ef27ab0c2aaf1452576f4b0b5561
ToppCell	PND01-03-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	CYBB EMILIN2 GSR LRRC25 ELANE ALDH3B1	3.19e-06	149	120	6	50f53018e525b3d252caa8bed9e075b1bb1086dd
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DRD4 WNT7A GRIK1 ADAM12 RYR3 SLC32A1	3.19e-06	149	120	6	10ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCell	E16.5-samps-Myeloid-Fetal_macrophage-Proliferative_Myeloid\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CYBB EMILIN2 HCST LRRC25 CD33 ALDH3B1	3.58e-06	152	120	6	e427758a6e39052616a0d8ecec0c1299e81d1d3c
ToppCell	facs-Lung-Endomucin_-18m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB EMILIN2 GSR SLC32A1 LRRC25 CD33	4.32e-06	157	120	6	2b60de520edf167f5ca790b478557a778435b3d9
ToppCell	facs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l8\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C5AR2 EMILIN2 GRIK1 GSR LRRC25 CD33	4.32e-06	157	120	6	5098675f64342c41c5ca3551b24962d10c83e64d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WNT7A EMILIN2 GRIK1 TMEM132C SLC32A1 WDR6	4.32e-06	157	120	6	741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYBB FADS6 GSR LRRC25 ELANE IL6R	4.32e-06	157	120	6	552fd5d09bbe81f58404ec38166feb30fc84def5
ToppCell	facs-Lung-18m-Hematologic-myeloid-neutrophil\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C5AR2 EMILIN2 HCST GSR LRRC25 CD33	5.17e-06	162	120	6	ad974426039f4952c59d27167eac24dc6ce63f5e
ToppCell	facs-Lung-18m-Hematologic-myeloid-neutrophil-neutrophil\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C5AR2 EMILIN2 HCST GSR LRRC25 CD33	5.17e-06	162	120	6	4e7e565091bce227d794a36af2e5dfc4a791efad
ToppCell	droplet-Fat-Scat-18m-Myeloid-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB EMILIN2 GSR LRRC25 DMKN ALDH3B1	5.74e-06	165	120	6	015f8f408d7fd17292defe63fa02b16eed642dfb
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYBB FN1 EMILIN2 GSR LRRC25 IL6R	5.74e-06	165	120	6	433771abefc5bcb89bdae64af45cce7407bffe5d
ToppCell	facs-Heart-RA-24m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB HCST RYR3 LRRC25 LRP2 ELANE	5.74e-06	165	120	6	995f1524965a4314938f27165166f0aaff9dea02
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR LRRC25 IL6R	5.95e-06	166	120	6	82fa07632f7e586698fbf37381715b40f9f6ae3a
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR LRRC25 IL6R	5.95e-06	166	120	6	bf6c35c3e67ef4ca98a38926c6f7923ecca0508a
ToppCell	facs-Lung-EPCAM-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR LRRC25 IL6R	5.95e-06	166	120	6	433128b7d964b32faa0bf437a02facc819ab1405
ToppCell	facs-Marrow-T_cells-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR LRRC25 ALDH3B1	5.95e-06	166	120	6	fab4da2537904ad114218f720e18a600f14a00a1
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR LRRC25 IL6R	5.95e-06	166	120	6	0d03926452414f232c77fd15d5f48d148f9fca3b
ToppCell	droplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB EMILIN2 GSR LRRC25 NFKB1 IL6R	6.37e-06	168	120	6	00cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB FN1 EMILIN2 GSR LRRC25 IL6R	6.37e-06	168	120	6	ab1fb9b2cc7c5853b7fbd373e1784a9a31f96d38
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYBB HCST CABLES1 CD33 LRRC56 ALDH3B1	6.59e-06	169	120	6	305cedbd97059029d7d2a248a8a4b6cfe281aa54
ToppCell	droplet-Marrow-BM-1m-Myeloid-monocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOP FN1 HGSNAT EMILIN2 LRRC25 IL6R	6.59e-06	169	120	6	8066b4c02c97d00034802cff2b39799ef44cc904
ToppCell	droplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB EMILIN2 GSR LRRC25 NFKB1 IL6R	6.59e-06	169	120	6	90c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCell	facs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB FN1 EMILIN2 GSR LRRC25 IL6R	6.59e-06	169	120	6	907e4c7d0df6dd46664d69834251aebca8e1dd1e
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WNT7A FIGNL2 CCNP EGFR GPR62 BICC1	6.59e-06	169	120	6	8f397cf4f9fd7c6fa88d01a95289ce2a6bc6938d
ToppCell	droplet-Fat-Scat\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 SLC39A1 EMILIN2 ADAM12 LRRC25 DMKN	6.81e-06	170	120	6	de722bea7527d6ad11b69f8e9589638f52854beb
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB HCST GSR MEGF9 CD33 MAP3K9	7.05e-06	171	120	6	ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB HCST GSR MEGF9 CD33 MAP3K9	7.05e-06	171	120	6	97ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYBB FN1 EMILIN2 GSR LRRC25 IL6R	7.29e-06	172	120	6	e72966ced5f2ee9e24ce9fd820d99a69a482a607
ToppCell	facs-Lung-24m-Hematologic-myeloid-classical_monocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB FN1 EMILIN2 GSR LRRC25 IL6R	7.29e-06	172	120	6	f557ec1b4d08b42559da02dd1f2387283c6380a2
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PDE3A WNT7A SORCS1 SLC32A1 EGFR SLC18A3	7.29e-06	172	120	6	7e1a7700a4c2b1d100da1d6e475e73498ebb605a
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYBB FN1 EMILIN2 GSR LRRC25 IL6R	7.29e-06	172	120	6	83730ea3b240b8e2f2a9fb6c34dd1408050867ff
ToppCell	droplet-Lung-nan-21m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR LRRC25 ALDH3B1	7.53e-06	173	120	6	9019049b1e2a24cb0bbbc620d64ef29dd18cc4c6
ToppCell	droplet-Lung-nan-21m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR LRRC25 ALDH3B1	7.53e-06	173	120	6	077029eecfe636a5baf5f70464e1713b3f6b4274
ToppCell	Immune_cells-Monocytes\|Immune_cells / Lineage and Cell class	CYBB FN1 HGSNAT EMILIN2 LRRC25 IL6R	7.53e-06	173	120	6	3eced40a65453a023a1673658592e7e2a099119b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	C5AR2 EMILIN2 HCST LRRC25 CD33 ALDH3B1	8.04e-06	175	120	6	e991ffa4d1d278a011592b9915cd35fe76db20cc
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 HGSNAT EMILIN2 LRRC25 IL6R	8.04e-06	175	120	6	69b59ec58e64644deb7e07f31ef495ef4a6f6276
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 HGSNAT EMILIN2 LRRC25 IL6R	8.04e-06	175	120	6	4f7498b5a0ed52c348a5f94bcd41d830ba7954ea
ToppCell	wk_20-22-Epithelial-PNS-Late_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	BRSK2 SORCS1 KCNA2 TENM3 NTN5 PLP1	8.31e-06	176	120	6	81924471d8a8c5bd8eedf294c007e25b6cd3e417
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYBB SELENOP GALC LRRC25 CD33 IL6R	8.58e-06	177	120	6	ab92ffc9624850a50c88e6b8f3a517ff2251ff15
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DRP2 BRSK2 SORCS1 KCNA2 MEGF9 PLP1	8.58e-06	177	120	6	59cf56c385c324f0844f20003d2b5049a2791e45
ToppCell	droplet-Spleen-nan-24m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 EMILIN2 GSR LRRC25 DMKN ELANE	8.58e-06	177	120	6	5f20a1a875d6f85ec07b097e6afdb07c2f8f88ff
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 EMILIN2 GSR LRRC25 DMKN ELANE	8.86e-06	178	120	6	be8af4d85b8835a85a168639c37857dcaa6b00bf
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FADS6 SORCS1 TENM3 LRP2 PAPPA MSLN	8.86e-06	178	120	6	a107dd98a07086ed0429116095ecda60c9dbef1e
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB FN1 EMILIN2 GSR LRRC25 ALDH3B1	9.15e-06	179	120	6	fa58fa0901eadb170e3d2facb2a3d8c5e624329a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC10A4 GRIK1 SLC32A1 KCNA3 EGFR LY6H	9.15e-06	179	120	6	97ba67a856680f24846244c0b92c886cc0e79537
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM12 PHGDH SORCS1 KCNA2 PAPPA PLP1	9.44e-06	180	120	6	d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM12 PHGDH SORCS1 KCNA2 PAPPA PLP1	9.44e-06	180	120	6	dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE3A SLC10A4 GRIK1 SORCS1 EGFR IL9	9.75e-06	181	120	6	2f3d04d22d4ac016e61709ea5af3d48885c946c4
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Monocytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYBB C5AR2 HCST LRRC25 CD33 IL6R	9.75e-06	181	120	6	bad77767e64cc093a827a6b0f3f401f3f108e457
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BRSK2 ADAM12 SORCS1 KCNA2 KCNA4 PLP1	9.75e-06	181	120	6	fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26A ABCC9 PIGG CABLES1 DMKN SLC15A4	9.75e-06	181	120	6	709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FN1 ABCC9 SORCS1 PAPPA LY6H NOVA1	1.01e-05	182	120	6	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE3A SLC10A4 GRIK1 RYR3 EGFR LGR6	1.01e-05	182	120	6	d3a037268f026eb2f84428b1821022503cef7756
ToppCell	NS-moderate-d_16-33-Lymphoid-NK\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PDE3A FN1 SORCS1 PAPPA PLP1 NOVA1	1.01e-05	182	120	6	fb503f8ecd013f1f2161a5841572b57cfcddb6fa
ToppCell	droplet-Lung-LUNG\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR LRRC25 ELANE	1.01e-05	182	120	6	a7887b81d4da1a61763c6b02f33de19efb321d42
ToppCell	droplet-Lung-30m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB FN1 GSR LRRC25 DMKN ELANE	1.04e-05	183	120	6	c752a7abdca087e230935af867bf8ae829b3f0cb
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A SORCS1 TMEM132C SPON2 PAPPA BICC1	1.04e-05	183	120	6	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE3A SLC10A4 GRIK1 SLC32A1 EGFR LY6H	1.04e-05	183	120	6	e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYBB C5AR2 EMILIN2 NFKB1 ELANE IL6R	1.07e-05	184	120	6	d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK1 TMEM132C SLC32A1 KCNA3 TENM3 PAPPA	1.07e-05	184	120	6	23515c28e1f42aab29cef9e5b4a7f45bda7f5520
ToppCell	droplet-Lung-LUNG-30m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 GSR LRRC25 DMKN ELANE	1.07e-05	184	120	6	52d62e1fcc92295d63197b2908083081b3ce1a6d
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PDE3A RYR3 TENM3 PAPPA LY6H HS3ST3B1	1.10e-05	185	120	6	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE3A SLC10A4 GRIK1 RYR3 EGFR LGR6	1.10e-05	185	120	6	0b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BRSK2 ADAM12 SORCS1 KCNA2 KCNA4 PLP1	1.10e-05	185	120	6	56c7a0dbf141728ac76b8c90af197719942ca67c
ToppCell	droplet-Lung-LUNG-30m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB FN1 EMILIN2 GSR DMKN ELANE	1.10e-05	185	120	6	2ca0b6c590c1e18122d18a728586fbd8c0024dc4
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYBB C5AR2 HCST LRRC25 CD33 IL6R	1.14e-05	186	120	6	c0a58e43a813441d3a1708236737b15db8bea10e
ToppCell	PCW_07-8.5-Neuronal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BRSK2 ADAM12 SORCS1 KCNA2 KCNA4 PLP1	1.14e-05	186	120	6	7a4bb42f3f6a27b463e48eafc587d9ab3386f2fb
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-MPO+_mono-neutrophil\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYBB HCST LRRC25 CD33 ELANE IL6R	1.17e-05	187	120	6	49c7ac6fa53ecc7395c2b02decd12dfe013e44e6
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCNP PHGDH EGFR DMKN SLCO1A2 BICC1	1.17e-05	187	120	6	9225caf66e06ebe57e90d677122acb6498607f36
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC10A4 GRIK1 SLC32A1 EGFR LY6H IL9	1.21e-05	188	120	6	433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Monocytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYBB EMILIN2 HCST LRRC25 CD33 IL6R	1.21e-05	188	120	6	085b61dfad373e5c39f2496539fbfed1b588115a
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRP2 ADAM12 KCNA2 SLC27A1 PLP1 CDH10	1.21e-05	188	120	6	c2101ded71fb16b8ddbc1f883911b1ed2a533ffc
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRP2 ADAM12 KCNA2 SLC27A1 PLP1 CDH10	1.21e-05	188	120	6	3b8b9161f0fdcbde302ce5b4c0bc874628211109
ToppCell	control-immature_Neutrophil\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CYBB CHKA CD33 LYPD3 ALDH3B1 IL6R	1.25e-05	189	120	6	bdfd120900ba58d5e54765f7b576e1f8cc2401bf
Drug	12 p	PDE3A ABCC9 CHKA BGLAP GSR FZD7 KCNA2 KCNA4 EGFR CD33	1.96e-06	274	120	10	CID000081248
Disease	Methionine sulfoxide measurement	TMEM132C SLC15A4 SLC23A3	1.17e-05	12	113	3	EFO_0021650
Disease	Common variable immunodeficiency	CR2 NFKB1 LRBA	1.52e-05	13	113	3	cv:C0009447
Disease	myocardial infarction (biomarker_via_orthology)	CYBB FN1 GSR SLC27A1 C8B IL6R	3.62e-05	160	113	6	DOID:5844 (biomarker_via_orthology)
Disease	serine/threonine-protein kinase BRSK2 measurement	BRSK2 BRSK1	4.35e-05	3	113	2	EFO_0803063
Disease	Alcoholic Intoxication, Chronic	DRD4 GRIK1 SLC22A18 EGFR NFKB1 CDH10 GABBR1	8.02e-05	268	113	7	C0001973
Disease	refractive error, age at onset, Myopia	PDE3A POLR2A GRIK1 KCNA4 TSPAN10 BICC1	1.02e-04	193	113	6	EFO_0004847, HP_0000545, MONDO_0004892
Disease	Alcohol abuse	DRD4 FN1 EGFR GABBR1	1.30e-04	67	113	4	C0085762
Disease	Lupus Erythematosus, Discoid	CYBB CR2	1.44e-04	5	113	2	C0024138
Disease	Recurrent infections	CR2 IL6R	1.44e-04	5	113	2	C0239998
Disease	polycythemia vera (is_marker_for)	GSR ELANE	1.44e-04	5	113	2	DOID:8997 (is_marker_for)
Disease	monocyte count	SELENOP FN1 CABLES1 SLC39A12 IFRD1 KCNA2 KCNA3 EGFR CD33 SLCO1A2 NFKB1 LINC00574 VARS1 IL6R NOTCH4	1.57e-04	1320	113	15	EFO_0005091
Disease	osteoporosis (is_marker_for)	BGLAP GSR	2.16e-04	6	113	2	DOID:11476 (is_marker_for)
Disease	Malignant neoplasm of breast	MAN2C1 FN1 SH2D3A ADAM12 PHGDH SORCS1 SLC22A18 SLC39A12 EGFR LGR6 LRBA CDH10 NOTCH4	2.43e-04	1074	113	13	C0006142
Disease	hypertension (biomarker_via_orthology)	CYBB FN1 ABCC9 STS EGFR GABBR1	2.47e-04	227	113	6	DOID:10763 (biomarker_via_orthology)
Disease	systemic lupus erythematosus	GALC DRD4 ANKRD27 TMEM132C LRRC25 SLC15A4 LRRC56 TARBP1 IL6R GABBR1 NOTCH4	2.54e-04	799	113	11	MONDO_0007915
Disease	Parkinsonism (biomarker_via_orthology)	ABCC9 GSR EGFR	3.00e-04	34	113	3	DOID:0080855 (biomarker_via_orthology)
Disease	bilirubin measurement	PDE3A ABCC9 SLC22A18 KCNA4 SLCO1A2 CYP26C1 LGR6 IL6R	3.09e-04	442	113	8	EFO_0004570
Disease	thalamus volume	GALC EGFR NFKB1 PAPPA	3.25e-04	85	113	4	EFO_0006935
Disease	systemic scleroderma	TMEM175 CR2 NFKB1 NOTCH4	3.25e-04	85	113	4	EFO_0000717
Disease	Endometrioma	SELENOP ABCC9 EGFR PAPPA HS3ST3B1	3.97e-04	161	113	5	C0269102
Disease	Endometriosis	SELENOP ABCC9 EGFR PAPPA HS3ST3B1	3.97e-04	161	113	5	C0014175
Disease	dementia (is_marker_for)	GSR EGFR	4.01e-04	8	113	2	DOID:1307 (is_marker_for)
Disease	diabetes mellitus (is_marker_for)	FN1 GSR EGFR	5.24e-04	41	113	3	DOID:9351 (is_marker_for)
Disease	end stage renal disease (is_marker_for)	FN1 BGLAP GSR	7.36e-04	46	113	3	DOID:783 (is_marker_for)
Disease	Immunoglobulin Deficiency, Late-Onset	CR2 NFKB1	7.82e-04	11	113	2	C2936665
Disease	Acquired Hypogammaglobulinemia	CR2 NFKB1	7.82e-04	11	113	2	C2936664
Disease	end stage renal disease (biomarker_via_orthology)	CYBB BGLAP LRP2	7.84e-04	47	113	3	DOID:783 (biomarker_via_orthology)
Disease	Malignant mesothelioma	FN1 EGFR NANOS1 MSLN	8.33e-04	109	113	4	C0345967
Disease	ocular hypertension, response to triamcinolone acetonide	GRIK1 TMEM132C VARS1	8.86e-04	49	113	3	EFO_0006954, EFO_1001069
Disease	ocular sarcoidosis	WNT7A EGFR LRP2 NOVA1	1.05e-03	116	113	4	EFO_0010723
Disease	hypertension (is_marker_for)	GSR PAPPA IL6R	1.11e-03	53	113	3	DOID:10763 (is_marker_for)
Disease	Neoplasm of lung	SLC22A18 EGFR	1.28e-03	14	113	2	cv:C0024121
Disease	Lung cancer	SLC22A18 EGFR	1.28e-03	14	113	2	cv:C0242379
Disease	LUNG CANCER	SLC22A18 EGFR	1.28e-03	14	113	2	211980
Disease	Generalized hypotonia	POLR2A FCSK	1.48e-03	15	113	2	C1858120
Disease	Common Variable Immunodeficiency	CR2 NFKB1	1.48e-03	15	113	2	C0009447
Disease	glycerate measurement	RYR3 SLC23A3	1.48e-03	15	113	2	EFO_0021029
Disease	Insulin Resistance	SELENOP STS EGFR	1.60e-03	60	113	3	C0021655
Disease	Insulin Sensitivity	SELENOP STS EGFR	1.60e-03	60	113	3	C0920563
Disease	response to opioid	SELENOP ADAM12 TMEM132C	1.67e-03	61	113	3	EFO_0008541
Disease	acute kidney failure (biomarker_via_orthology)	FN1 GSR EGFR	1.67e-03	61	113	3	DOID:3021 (biomarker_via_orthology)
Disease	Schizophrenia	DRD4 GRIK1 ADAM12 LRP2 ALDH3B1 PLP1 IL6R GABBR1 NOTCH4 SLC23A3	2.12e-03	883	113	10	C0036341
Disease	Feeding difficulties	POLR2A FCSK	2.14e-03	18	113	2	C0232466
Disease	response to clozapine	FZD7 SLC39A12	2.14e-03	18	113	2	GO_0097338
Disease	Female Urogenital Diseases	AMHR2 WNT7A	2.14e-03	18	113	2	C1720887
Disease	age at onset, Parkinson disease	TMEM175 KLHDC1	2.14e-03	18	113	2	EFO_0004847, MONDO_0005180
Disease	X-11470 measurement	VARS1 NOTCH4	2.38e-03	19	113	2	EFO_0021241
Disease	response to alcohol	PIGG EGFR NOVA1	3.02e-03	75	113	3	EFO_0005526
Disease	Attention Deficit Disorder	DRD4 STS	3.19e-03	22	113	2	C0041671
Disease	Minimal Brain Dysfunction	DRD4 STS	3.19e-03	22	113	2	C1321905
Disease	Carcinoma of lung	SLC22A18 EGFR	3.49e-03	23	113	2	C0684249
Disease	epilepsy (implicated_via_orthology)	CHKA KCNA2 KCNA3 KCNA4	3.62e-03	163	113	4	DOID:1826 (implicated_via_orthology)
Disease	pulmonary hypertension (biomarker_via_orthology)	CYBB PDE3A RYR3	3.63e-03	80	113	3	DOID:6432 (biomarker_via_orthology)
Disease	Intrahepatic Cholangiocarcinoma	EGFR MSLN	3.80e-03	24	113	2	C0345905
Disease	nephrotic syndrome (implicated_via_orthology)	MPV17 GAPVD1	3.80e-03	24	113	2	DOID:1184 (implicated_via_orthology)
Disease	Attention deficit hyperactivity disorder	DRD4 STS	3.80e-03	24	113	2	C1263846
Disease	Extrahepatic Cholangiocarcinoma	EGFR MSLN	3.80e-03	24	113	2	C3805278
Disease	Carcinoma, Pancreatic Ductal	NOTCH4 MSLN	3.80e-03	24	113	2	C0887833

Protein segments in the cluster

Peptide	Gene	Start	Entry
SLAADLAGDALPGCL	LINC01547	71	P58512
TLVPLVGALAAGNCV	ALDH3B1	121	P43353
VCGKALLTPVAIAAG	GSR	376	P00390
ACDQLALGVAALFGP	GRIK1	96	P39086
AINGTSLVGLPLAAC	APBA3	446	O96018
LALAGALLAPCEARG	ADAM12	16	O43184
LADLLGFAGPLCISG	ABCC9	306	O60706
CLGLLAALAGSSPQV	CCNP	211	Q9H8S5
GLACPSLDILASAGL	BICC1	436	Q9H694
SCAIGDLGLALVLPG	AMHR2	346	Q16671
PVGALLAALCQFGLL	SLC10A4	136	Q96EP9
KLGAGFACLLSVPIL	ANKRD27	81	Q96NW4
GSLCAIAGVLTIALP	KCNA2	391	P16389
AALLPACTLGVAALG	GPR62	96	Q9BZJ7
CAGSCAAAPGLLLLG	HS3ST3B1	51	Q9Y662
FLCGDAGPLAVAAVL	LANCL1	106	O43813
LGCLALAGLAAALPL	LGR6	691	Q9HBX8
LAGLAAALPLASVGE	LGR6	696	Q9HBX8
VAGLLACAATLALGA	KCNK15	161	Q9H427
GCSLALAAVFPLGLD	GABBR1	636	Q9UBS5
VSGCLLLGLAIAGPV	LRRC25	171	Q8N386
AIGGAGVTALLALCL	CD33	261	P20138
ACLALERVAAGQGLP	METTL25	456	Q8N6Q8
GSLLCLPGSGSVLLD	GAPVD1	686	Q14C86
SCGVILFALLVGALP	BRSK2	201	Q8IWQ3
PLGCSGLSSALLAAG	BARX1	91	Q9HBU1
LSPFAGRAAAVLLGC	NANOS1	151	Q8WY41
GRAAAVLLGCAPAAA	NANOS1	156	Q8WY41
GPLIAANSGSLCFLI	OR4C45	191	A6NMZ5
LSLPAAGVVLSCLAA	PDE3A	186	Q14432
GSLCAIAGVLTIALP	KCNA3	461	P22001
ACGGILPLLSAATSA	LRBA	1371	P50851
SLPSLGGLALLCCAA	MEGF9	11	Q9H1U4
GEAAGGPLCLSLSAL	KIF26A	646	Q9ULI4
GSCGTPALGSLLFLL	MSLN	11	Q13421
TLLLALVACLAPASG	LRP2	11	P98164
GLLSAALGCGLAERP	PAPPA	11	Q13219
LLLCSVAGQGCPTLA	IL9	11	P15248
LLSAAVAAPVLCGLN	DRD4	161	P21917
LALLAVLLCSAPAHG	LY6H	11	O94772
CVAPTAGLAALLLAV	LYPD3	326	O95274
IVLDLCAAPGGKTLA	NSUN4	176	Q96CB9
ALAALCIAGQAGAKP	BGLAP	11	P02818
DPSGGALLLCGLVAL	CYP2U1	31	Q7Z449
APGALLKAAFICAGI	FCSK	791	Q8N0W3
AAAPLSSLGLCALVL	FZD7	6	O75084
CALVLALLGALSAGA	FZD7	16	O75084
TAGAALLALLAALCP	EGFR	6	P00533
CALLAALLAAPGAAL	IL6R	6	P08887
LALVAPGVLGISCGS	CR2	11	P20023
LAAAERGGCIALAAP	CABLES1	111	Q8TDN4
AALSADLCFLALGPA	C5AR2	126	Q9P296
LLALCLGSGEAGPLQ	DMKN	11	Q6E0U4
PAGLSTGALIAILLC	CDH10	606	Q9Y6N8
GPGLLLLAVQCLGTA	FN1	6	P02751
LGLLLSCGSGSAAPA	CHKA	16	P35790
LLLLLTGPAACAASP	FRRS1L	16	Q9P0K9
GQPAAAAALCLELAA	F8A1;	136	P23610
LPLAALQALGEAASC	F8A1;	176	P23610
PAGCSLGLKAEAALV	LINC00574	111	Q9H8X3
CLQILAAGLFLPGSV	ILF2	271	Q12905
VLGAAGTALLCAGLL	CYP26C1	11	Q6V0L0
SCGVILFALLVGALP	BRSK1	216	Q8TDC3
AALASVLCIQLGPGI	IFRD1	146	O00458
GCGSLSLPLLAGLVA	HCST	41	Q9UBK5
LLSAAAAALCAGEPG	MAN2C1	606	Q9NTJ4
LGSALALARAPAACL	CYBB	46	P04839
LFLCGGLSADNIPLS	KLHDC1	261	Q8N7A1
LAASVLSAALLAPGG	HGSNAT	41	Q68CP4
FLACVLPALLLGGTA	ELANE	11	P08246
ALALLALVGAGLCHA	EMILIN2	16	Q9BXX0
AGGALQVPLLACLDG	FIGNL2	506	A6NMB9
LLVAAFGLVLQGPCA	DCST2	96	Q5T1A1
AGSAGRAAVPLLLCA	GALC	21	P54803
PLLAAPATRAALCGS	SLC15A4	121	Q8N697
NLCFEPDALLLIAGG	SLC39A12	86	Q504Y0
GPADRAAVLGILCSL	CCDC103	156	Q8IW40
FLLCAALGCLSLPGS	C8B	16	P07358
GALAASAPVLAVAGL	DPP7	181	Q9UHL4
VALLGCGAVLAATGL	MAP3K9	751	P80192
VPCLSLKLLNGSVGA	DRP2	56	Q13474
DCAILALSLFALPAG	FADS6	56	Q8N9I5
LGACLRGALTNLPAG	PIDD1	106	Q9HB75
AEVLPTAAAAAGLLG	NOVA1	276	P51513
LAAAATALTCLLPGL	LY6G6D	116	O95868
ACGATLPALGLRSSA	VARS1	111	P26640
ALGLAVIGASSCIVP	SLC18A3	361	Q16572
PAAALGKALCALLLA	SPON2	6	Q9BUD6
AAPLCGALSLLLGAL	TMEM132C	11	Q8N3T6
CGLADLDGIASLPAL	LRRC56	126	Q8IYG6
CNGSLTLALGGPFLL	NTN5	61	Q8WTR8
AALNCLGLLHVPLGV	STS	201	P08842
LGCFLPLVGALNGLS	MPV17	101	P39210
RGAPAIALVGCLSLA	MRI1	46	Q9BV20
CLSLAVELQAGAGGP	MRI1	56	Q9BV20
GPLIGLLLASFCANV	SLCO1A2	206	P46721
SLGALDLLGPATGCL	SERTAD1	151	Q9UHV2
CSPVAGVILLALGAL	NOTCH4	1451	Q99466
GLALALCLLPSGGTE	SELENOP	6	P49908
QCPAILAALATLLGA	SLC22A18	181	Q96BI1
AHLVGLLCVGLGLSP	SLC23A3	396	Q6PIS1
ALGGLVNAVFLLAPC	TICRR	146	Q7Z2Z1
LGIVLQGPALCFAAA	TMEM175	186	Q9BSA9
GCLLRTSVAPAAALA	MINPP1	6	Q9UNW1
PLAFCLGTSGAKALI	SLC27A1	166	Q6PCB7
AGGVFLATCLLDLLP	SLC39A1	76	Q9NY26
LGECLASLAAAIPVA	RYR3	3051	Q15413
ALAGALAVLGCSGPL	SH2D3A	371	Q9BRG2
GQLAPAGTGCFDLLL	POLR2A	1461	P24928
KLLAPVALACGIDGS	TENM3	1171	Q9P273
ALLARCPTAGLAGGL	TMEM201	6	Q5SNT2
LLLLASGPGGVVACL	WDR6	451	Q9NNW5
AEALLLADVCGGLLP	ZACN	241	Q401N2
LGGLVVSAASLAGCL	TSPAN10	126	Q9H1Z9
ALGASIICNKIPGLA	WNT7A	31	O00755
AGNCLSPAVIVGLLK	PHGDH	366	O43175
GSLTGAGLCFLLPSL	SLC32A1	461	Q9H598
PRALLGALCQGEASA	TARBP1	16	Q13395
TGPILFCVALGATLL	YIPF7	151	Q8N8F6
PLALFLVCLCSGLGA	TMEM41B	146	Q5BJD5
CSPVSKAALALGLLG	PIGG	716	Q5H8A4
ALLAGAGLLILCAPG	SORCS1	16	Q8WY21
DIVLNGPSGSLLALC	WDR87	161	Q6ZQQ6
LASALPGALSITALC	TMEM127	31	O75204
CLAASGVGALLLEVP	nan	156	Q6ZTC4
GSLCAIAGVLTIALP	KCNA4	541	P22459
LVGAPFASLVATGLC	PLP1	11	P60201
SNSLPCLLLLVAAGA	NFKB1	661	P19838