Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent FeS chaperone activity

NUBP1 NUBPL NUBP2

9.98e-093443GO:0140663
GeneOntologyMolecularFunction4 iron, 4 sulfur cluster binding

NUBP1 DDX12P NUBPL NUBP2

3.41e-0647444GO:0051539
GeneOntologyMolecularFunctionmolecular carrier activity

NUBP1 RAN EMC7 NUBPL NUBP2

3.87e-06108445GO:0140104
GeneOntologyMolecularFunctionmetallochaperone activity

NUBP1 NUBPL NUBP2

7.96e-0618443GO:0016530
GeneOntologyMolecularFunctioniron-sulfur cluster binding

NUBP1 DDX12P NUBPL NUBP2

2.60e-0578444GO:0051536
GeneOntologyMolecularFunctionmetal cluster binding

NUBP1 DDX12P NUBPL NUBP2

3.32e-0583444GO:0051540
GeneOntologyMolecularFunctionATP-dependent activity

NUBP1 BPTF ABCC9 DDX12P NUBPL RUVBL2 NUBP2 HELB

5.09e-05614448GO:0140657
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

BPTF DDX12P RUVBL2 HELB

1.74e-04127444GO:0008094
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

NUBP1 ABCC9 RAN DDX12P GIMAP7 RUVBL2 AGAP2 HELB

2.55e-04775448GO:0017111
GeneOntologyMolecularFunction5'-3' DNA helicase activity

DDX12P HELB

2.58e-0411442GO:0043139
GeneOntologyMolecularFunctionDNA helicase activity

DDX12P RUVBL2 HELB

3.45e-0462443GO:0003678
GeneOntologyMolecularFunctionnucleosomal DNA binding

H1-5 H1-1 H1-3

4.33e-0467443GO:0031492
GeneOntologyMolecularFunctionpyrophosphatase activity

NUBP1 ABCC9 RAN DDX12P GIMAP7 RUVBL2 AGAP2 HELB

4.34e-04839448GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

NUBP1 ABCC9 RAN DDX12P GIMAP7 RUVBL2 AGAP2 HELB

4.37e-04840448GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

NUBP1 ABCC9 RAN DDX12P GIMAP7 RUVBL2 AGAP2 HELB

4.37e-04840448GO:0016818
GeneOntologyMolecularFunctionchromatin DNA binding

H1-5 H1-1 RUVBL2 H1-3

4.94e-04167444GO:0031490
GeneOntologyMolecularFunctionK48-linked deubiquitinase activity

USP26 USP8

9.70e-0421442GO:1990380
GeneOntologyMolecularFunctionchromatin binding

H1-5 RAN H1-1 DDX12P RUVBL2 NUP153 H1-3

1.07e-03739447GO:0003682
GeneOntologyMolecularFunctionnucleosome binding

H1-5 H1-1 H1-3

1.31e-0398443GO:0031491
GeneOntologyMolecularFunctionstructural constituent of chromatin

H1-5 H1-1 H1-3

1.39e-03100443GO:0030527
GeneOntologyMolecularFunctionbeta-catenin binding

MET RUVBL2 AXIN1

2.34e-03120443GO:0008013
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

BPTF DDX12P RUVBL2 HELB

2.60e-03262444GO:0140097
GeneOntologyMolecularFunctionATP hydrolysis activity

NUBP1 ABCC9 DDX12P RUVBL2 HELB

2.75e-03441445GO:0016887
GeneOntologyMolecularFunctionhelicase activity

DDX12P RUVBL2 HELB

5.08e-03158443GO:0004386
GeneOntologyBiologicalProcessnegative regulation of DNA recombination

H1-5 H1-1 HELB H1-3

5.17e-0655434GO:0045910
GeneOntologyBiologicalProcessregulation of DNA recombination

H1-5 H1-1 RUVBL2 HELB H1-3

1.47e-05150435GO:0000018
GeneOntologyBiologicalProcessiron-sulfur cluster assembly

NUBP1 NUBPL NUBP2

2.97e-0529433GO:0016226
GeneOntologyBiologicalProcessmetallo-sulfur cluster assembly

NUBP1 NUBPL NUBP2

2.97e-0529433GO:0031163
GeneOntologyBiologicalProcesschromosome condensation

H1-5 H1-1 H1-3

1.37e-0448433GO:0030261
GeneOntologyBiologicalProcessnegative regulation of protein catabolic process

USP26 USP8 MYCBP2 AGAP2

1.58e-04131434GO:0042177
GeneOntologyBiologicalProcessestablishment of protein localization to chromatin

H1-5 RUVBL2

1.89e-0410432GO:0071169
GeneOntologyCellularComponenteuchromatin

H1-5 H1-1 RUVBL2 H1-3

1.73e-0572454GO:0000791
GeneOntologyCellularComponentnucleosome

H1-5 H1-1 RUVBL2 H1-3

2.20e-04138454GO:0000786
DomainParA

NUBP1 NUBPL NUBP2

1.22e-083443PF10609
DomainMrp/NBP35_ATP-bd

NUBP1 NUBPL NUBP2

1.22e-083443IPR019591
DomainYlxH/NBP35

NUBP1 NUBPL NUBP2

1.22e-083443IPR033756
DomainMrp_CS

NUBP1 NUBPL NUBP2

1.22e-083443IPR000808
DomainMRP

NUBP1 NUBPL NUBP2

1.22e-083443PS01215
DomainHistone_H5

H1-5 H1-1 H1-3

6.78e-078443IPR005819
DomainH15

H1-5 H1-1 H1-3

3.43e-0613443SM00526
DomainLinker_histone

H1-5 H1-1 H1-3

3.43e-0613443PF00538
DomainH15

H1-5 H1-1 H1-3

3.43e-0613443PS51504
DomainHistone_H1/H5_H15

H1-5 H1-1 H1-3

4.36e-0614443IPR005818
Domain-

GIMAP4 NUBP1 ABCC9 RAN GIMAP7 NUBPL RUVBL2 NUBP2 AGAP2 HELB

7.04e-0674644103.40.50.300
DomainP-loop_NTPase

GIMAP4 NUBP1 ABCC9 RAN GIMAP7 NUBPL RUVBL2 NUBP2 AGAP2 HELB

2.15e-058484410IPR027417
DomainAIG1

GIMAP4 GIMAP7

1.51e-048442PF04548
DomainG_AIG1

GIMAP4 GIMAP7

1.51e-048442IPR006703
DomainG_AIG1

GIMAP4 GIMAP7

1.51e-048442PS51720
DomainCarboxyPept-like_regulatory

EMC7 TENM4

7.21e-0417442IPR008969
DomainRCC1

HERC3 MYCBP2

1.00e-0320442PF00415
DomainRCC1_1

HERC3 MYCBP2

1.11e-0321442PS00625
DomainRCC1_2

HERC3 MYCBP2

1.11e-0321442PS00626
DomainRCC1_3

HERC3 MYCBP2

1.11e-0321442PS50012
DomainReg_chr_condens

HERC3 MYCBP2

1.22e-0322442IPR000408
Domain-

HERC3 MYCBP2

1.22e-03224422.130.10.30
DomainRCC1/BLIP-II

HERC3 MYCBP2

1.33e-0323442IPR009091
DomainAAA+_ATPase

NUBP1 ABCC9 RUVBL2

4.72e-03144443IPR003593
DomainAAA

NUBP1 ABCC9 RUVBL2

4.72e-03144443SM00382
PathwayREACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION

H1-5 H1-1 H1-3

2.99e-0613323M1018
PathwayREACTOME_FORMATION_OF_SENESCENCE_ASSOCIATED_HETEROCHROMATIN_FOCI_SAHF

H1-5 H1-1 H1-3

7.07e-0617323M27189
PathwayREACTOME_APOPTOTIC_EXECUTION_PHASE

H1-5 H1-1 H1-3

2.18e-0452323M2341
PathwayBIOCARTA_NPC_PATHWAY

RAN NUP153

2.71e-0411322M22033
PathwayREACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION

H1-5 H1-1

3.25e-0412322MM14554
PathwayREACTOME_CYTOSOLIC_IRON_SULFUR_CLUSTER_ASSEMBLY

NUBP1 NUBP2

3.83e-0413322M27193
PathwayWP_IRONSULFUR_CLUSTER_BIOGENESIS

NUBP1 NUBP2

5.15e-0415322M48050
PathwayREACTOME_FORMATION_OF_SENESCENCE_ASSOCIATED_HETEROCHROMATIN_FOCI_SAHF

H1-5 H1-1

5.15e-0415322MM14902
PathwayREACTOME_DNA_DAMAGE_TELOMERE_STRESS_INDUCED_SENESCENCE

H1-5 H1-1 H1-3

7.47e-0479323M27191
PathwayREACTOME_NEGATIVE_REGULATION_OF_MET_ACTIVITY

MET USP8

1.02e-0321322M27645
PathwayREACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION

LGR4 USP8

1.02e-0321322M27401
PathwayREACTOME_NEGATIVE_REGULATION_OF_MET_ACTIVITY

MET USP8

1.02e-0321322MM15347
Pubmed

Chromatin condensing functions of the linker histone C-terminal domain are mediated by specific amino acid composition and intrinsic protein disorder.

H1-5 H1-1 H1-3

8.65e-09446319072710
Pubmed

The mouse histone H1 genes: gene organization and differential regulation.

H1-5 H1-1 H1-3

2.16e-0854639300059
Pubmed

A compendium of the histone H1 family of somatic subtypes: an elusive cast of characters and their characteristics.

H1-5 H1-1 H1-3

2.16e-08546311467742
Pubmed

A proposal for a coherent mammalian histone H1 nomenclature correlated with amino acid sequences.

H1-5 H1-1 H1-3

2.16e-0854638003976
Pubmed

Expression of murine H1 histone genes during postnatal development.

H1-5 H1-1 H1-3

2.16e-0854639655912
Pubmed

Characterization of phosphorylation sites on histone H1 isoforms by tandem mass spectrometry.

H1-5 H1-1 H1-3

4.32e-08646315595731
Pubmed

The preferential binding of histone H1 to DNA scaffold-associated regions is determined by its C-terminal domain.

H1-5 H1-1 H1-3

4.32e-08646315562002
Pubmed

The multifunctional protein nucleophosmin (NPM1) is a human linker histone H1 chaperone.

H1-5 H1-1 H1-3

4.32e-08646321425800
Pubmed

Hormone-mediated dephosphorylation of specific histone H1 isoforms.

H1-5 H1-1 H1-3

4.32e-08646311479299
Pubmed

Linker histone transitions during mammalian oogenesis and embryogenesis.

H1-5 H1-1 H1-3

4.32e-0864639499577
Pubmed

Histone H1 subtype preferences of DFF40 and possible nuclear localization of DFF40/45 in normal and trichostatin A-treated NB4 leukemic cells.

H1-5 H1-1 H1-3

4.32e-08646319882353
Pubmed

H1 family histones in the nucleus. Control of binding and localization by the C-terminal domain.

H1-5 H1-1 H1-3

4.32e-08646315911621
Pubmed

All known human H1 histone genes except the H1(0) gene are clustered on chromosome 6.

H1-5 H1-1 H1-3

7.55e-0874638325638
Pubmed

Dynamic changes in H1 subtype composition during epigenetic reprogramming.

H1-5 H1-1 H1-3

2.58e-071046328794128
Pubmed

High-throughput kinase assays with protein substrates using fluorescent polymer superquenching.

H1-5 H1-1 H1-3

2.58e-071046315927069
Pubmed

Role of H1 linker histones in mammalian development and stem cell differentiation.

H1-5 H1-1 H1-3

3.55e-071146326689747
Pubmed

A unified phylogeny-based nomenclature for histone variants.

H1-5 H1-1 H1-3

4.72e-071246322650316
Pubmed

Characterization of the mouse histone gene cluster on chromosome 13: 45 histone genes in three patches spread over 1Mb.

H1-5 H1-1 H1-3

6.14e-07134638858344
Pubmed

CRL4DCAF8 dependent opposing stability control over the chromatin remodeler LSH orchestrates epigenetic dynamics in ferroptosis.

H1-5 H1-1 H1-3

1.20e-061646333288900
Pubmed

Ran GTPase promotes cancer progression via Met recepto-rmediated downstream signaling.

MET RAN

1.71e-06246227716616
Pubmed

The nucleotide-binding proteins Nubp1 and Nubp2 are negative regulators of ciliogenesis.

NUBP1 NUBP2

1.71e-06246223807208
Pubmed

Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis.

NUBP1 NUBP2

1.71e-06246218573874
Pubmed

Comparison of intracellular localization of Nubp1 and Nubp2 using GFP fusion proteins.

NUBP1 NUBP2

1.71e-06246219263241
Pubmed

Molecular characterization of the Ran-binding zinc finger domain of Nup153.

RAN NUP153

1.71e-06246217426026
Pubmed

USP8/UBPy-regulated sorting and the development of sperm acrosome: the recruitment of MET.

MET USP8

1.71e-06246225744385
Pubmed

Myc binds the pluripotency factor Utf1 through the basic-helix-loop-helix leucine zipper domain.

H1-5 H1-1 RUVBL2

2.07e-061946323665319
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

H1-5 KRT1 BPTF USP8 RAN H1-1 INTS12 LYST AGAP2 EML6 H1-3

2.10e-061442461135575683
Pubmed

Motor protein KIFC5A interacts with Nubp1 and Nubp2, and is implicated in the regulation of centrosome duplication.

NUBP1 NUBP2

5.13e-06346216638812
Pubmed

Human spleen histone H1. Isolation and amino acid sequences of three minor variants, H1a, H1c, and H1d.

H1-5 H1-3

5.13e-0634622613692
Pubmed

Immune-associated nucleotide-1 (IAN-1) is a thymic selection marker and defines a novel gene family conserved in plants.

GIMAP4 GIMAP7

5.13e-06346210528200
Pubmed

The C-terminal domain (CTD) in linker histones antagonizes anti-apoptotic proteins to modulate apoptotic outcomes at the mitochondrion.

H1-1 H1-3

5.13e-06346224525734
Pubmed

Individual binding pockets of importin-beta for FG-nucleoporins have different binding properties and different sensitivities to RanGTP.

RAN NUP153

5.13e-06346218845677
Pubmed

Carrier-independent nuclear import of the transcription factor PU.1 via RanGTP-stimulated binding to Nup153.

RAN NUP153

5.13e-06346215632149
Pubmed

A novel family of katanin-like 2 protein isoforms (KATNAL2), interacting with nucleotide-binding proteins Nubp1 and Nubp2, are key regulators of different MT-based processes in mammalian cells.

NUBP1 NUBP2

5.13e-06346226153462
Pubmed

A novel MET-interacting protein shares high sequence similarity with RanBPM, but fails to stimulate MET-induced Ras/Erk signaling.

MET RAN

5.13e-06346214684163
Pubmed

Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo.

MET USP8

1.03e-05446217452457
Pubmed

MSX1 cooperates with histone H1b for inhibition of transcription and myogenesis.

H1-5 H1-1

1.03e-05446215192231
Pubmed

Computational and biochemical identification of a nuclear pore complex binding site on the nuclear transport carrier NTF2.

RAN NUP153

1.03e-05446215522285
Pubmed

MYCBP2 Is a Guanosine Exchange Factor for Ran Protein and Determines Its Localization in Neurons of Dorsal Root Ganglia.

RAN MYCBP2

1.03e-05446226304119
Pubmed

Nuclear reformation after mitosis requires downregulation of the Ran GTPase effector RanBP1 in mammalian cells.

RAN NUP153

1.03e-05446220658144
Pubmed

Distribution of somatic H1 subtypes is non-random on active vs. inactive chromatin II: distribution in human adult fibroblasts.

H1-5 H1-3

1.03e-05446211746507
Pubmed

The distribution of somatic H1 subtypes is non-random on active vs. inactive chromatin: distribution in human fetal fibroblasts.

H1-5 H1-3

1.03e-05446210997781
Pubmed

Isolation of two murine H1 histone genes and chromosomal mapping of the H1 gene complement.

H1-5 H1-3

1.03e-0544628589518
Pubmed

Human histone gene organization: nonregular arrangement within a large cluster.

H1-5 H1-1 H1-3

1.38e-05354639119399
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

OAS1 ABCC9 RAN H1-1 PLP1 SIPA1L1 H1-3

1.64e-0562146722794259
Pubmed

A giant nucleopore protein that binds Ran/TC4.

RAN NUP153

1.71e-0554627603572
Pubmed

Human immune associated nucleotide 1: a member of a new guanosine triphosphatase family expressed in resting T and B cells.

GIMAP4 GIMAP7

1.71e-05546211964296
Pubmed

Structural insights into the mechanism of GTPase activation in the GIMAP family.

GIMAP4 GIMAP7

1.71e-05546223454188
Pubmed

Characterization of the histone H1-binding protein, NASP, as a cell cycle-regulated somatic protein.

H1-1 H1-3

1.71e-05546210893414
Pubmed

Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains.

RAN NUP153

1.71e-05546212138183
Pubmed

Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins.

RAN NUP153

1.71e-05546211777942
Pubmed

USP8 modulates ubiquitination of LRIG1 for Met degradation.

MET USP8

1.71e-05546224828152
Pubmed

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.

H1-5 BPTF H1-1 MYCBP2

1.72e-0511646421282530
Pubmed

Structural and functional genomics and evolutionary relationships in the cluster of genes encoding murine 2',5'-oligoadenylate synthetases.

OAS1 LAP3

2.56e-05646214559211
Pubmed

Nup153 is an M9-containing mobile nucleoporin with a novel Ran-binding domain.

RAN NUP153

2.56e-05646210202161
Pubmed

Demonstration of in vitro interaction between tumor suppressor lysyl oxidase and histones H1 and H2: definition of the regions involved.

H1-5 H1-1

2.56e-05646212686141
Pubmed

Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma.

H1-5 H1-3

3.58e-05746224435047
Pubmed

Cloning and characterization of RLPK, a novel RSK-related protein kinase.

H1-5 H1-1

3.58e-0574629873047
Pubmed

USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling.

LGR4 AXIN1

3.58e-05746233786993
Pubmed

Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma.

MET USP8

3.58e-05746229880877
Pubmed

Human ortholog to mouse gene imap38 encoding an ER-localizable G-protein belongs to a gene family clustered on chromosome 7q32-36.

GIMAP4 GIMAP7

4.77e-05846211814688
Pubmed

Two novel mouse genes--Nubp2, mapped to the t-complex on chromosome 17, and Nubp1, mapped to chromosome 16--establish a new gene family of nucleotide-binding proteins in eukaryotes.

NUBP1 NUBP2

4.77e-05846210486206
Pubmed

A novel chromatin protein, distantly related to histone H2A, is largely excluded from the inactive X chromosome.

H1-5 H1-1

4.77e-05846211266453
Pubmed

Comparative analysis of the human gimap gene cluster encoding a novel GTPase family.

GIMAP4 GIMAP7

6.12e-05946215474311
Pubmed

Substrate specificity analysis and novel substrates of the protein lysine methyltransferase NSD1.

H1-5 H1-3

6.12e-05946224412544
Pubmed

Cloning and characterization of human karyopherin beta3.

RAN NUP153

6.12e-0594629114010
Pubmed

Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily.

RAN NUP153

6.12e-05946211024021
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

ZDHHC5 LGR4 MET USP8 INTS12 NUBPL SIRT3 NUBP2

6.81e-05106146833845483
Pubmed

Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3.

H1-5 RAN H1-1 LAP3 H1-3

7.65e-0533246530595499
Pubmed

Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase.

H1-5 H1-1

7.65e-05104627629134
Pubmed

N6-Methyladenosine modification of the TRIM7 positively regulates tumorigenesis and chemoresistance in osteosarcoma through ubiquitination of BRMS1.

H1-5 KRT1

9.34e-051146232853985
Pubmed

Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.

LGR4 KRT1

9.34e-051146220223988
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ZDHHC5 MET OAS1 FRMD4A NUBPL TMEM51

1.00e-0456946630639242
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

H1-5 MET FRMD4A TENM4 MYCBP2 RUVBL2 SIPA1L1 AGAP2

1.11e-04113946836417873
Pubmed

Regulation of bone formation and remodeling by G-protein-coupled receptor 48.

LGR4 IBSP

1.12e-041246219605502
Pubmed

A standardized nomenclature for mammalian histone genes.

H1-5 H1-1 H1-3

1.31e-047446336180920
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

H1-5 RAN H1-1 RUVBL2 LAP3 NUBP2 H1-3

1.45e-0487846737223481
Pubmed

The human and mouse replication-dependent histone genes.

H1-5 H1-1 H1-3

1.48e-047746312408966
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

VPS13D SIPA1L1 AXIN1 HELB

1.70e-0420946436779422
Pubmed

Tandem immunoprecipitation approach to identify HIV-1 Gag associated host factors.

H1-5 H1-3

2.03e-041646224690621
Pubmed

Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer.

H1-5 H1-1 H1-3

2.20e-048846326318153
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

KRT1 BPTF RUVBL2 ZNF516 EML6

2.29e-0442046528065597
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ZDHHC5 MET USP8 NUBPL TMEM51

2.31e-0442146536976175
Pubmed

Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.

KRT1 RAN LAP3

2.35e-04904631602151
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

H1-5 SIPA1L1 AGAP2 H1-3

2.49e-0423146416452087
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RAN MYCBP2 PLP1 NUP153 SIPA1L1 ZNF516 AGAP2

2.55e-0496346728671696
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

H1-5 KRT1 RAN RUVBL2 LAP3 NUP153 NUBP2 H1-3

3.01e-04131846830463901
Pubmed

Plasticity in the Glucagon Interactome Reveals Novel Proteins That Regulate Glucagon Secretion in α-TC1-6 Cells.

H1-5 RAN H1-1 H1-3

3.21e-0424746430713523
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

H1-5 BPTF NUP153 H1-3

3.36e-0425046433536335
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

USP8 MYCBP2 SIPA1L1

3.39e-0410246315778465
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

BPTF RAN RUVBL2 NUP153

4.55e-0427146432433965
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

H1-5 H1-1 VPS13D H1-3

4.94e-0427746430745168
Pubmed

Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice.

NUBP1 NUBP2

5.04e-042546223028652
Pubmed

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer.

KRT1 RAN RUVBL2 H1-3

5.64e-0428746436180891
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

H1-5 BPTF INTS12 MYCBP2 RUVBL2 NUP153 ZNF516

5.75e-04110346734189442
Pubmed

Interactome of Aiolos/Ikaros Reveals Combination Rationale of Cereblon Modulators with HDAC Inhibitors in DLBCL.

H1-5 RUVBL2 H1-3

5.86e-0412346335583604
Pubmed

Antiviral inhibition targeting the HCMV kinase pUL97 requires pUL27-dependent degradation of Tip60 acetyltransferase and cell-cycle arrest.

RAN RUVBL2

5.88e-042746221320693
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

H1-5 MUC19 RAN MYCBP2 RUVBL2 H1-3

6.51e-0480746630575818
Pubmed

EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.

RAN RUVBL2 ZNF516

6.58e-0412846323858473
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

RAN MYCBP2 RUVBL2 NUP153 AXIN1 H1-3

6.59e-0480946632129710
CytobandEnsembl 112 genes in cytogenetic band chr6p22

H1-5 H1-1 NUP153 H1-3

5.62e-04378464chr6p22
Cytoband7q36.1

GIMAP4 GIMAP7

2.53e-03744627q36.1
CytobandEnsembl 112 genes in cytogenetic band chr4q22

HERC3 IBSP

2.53e-0374462chr4q22
GeneFamilyCytosolic iron-sulfur assembly components

NUBP1 NUBP2

6.08e-0563721028
GeneFamilyGTPases, IMAP

GIMAP4 GIMAP7

1.13e-048372580
GeneFamilyHistones

H1-5 H1-1 H1-3

1.71e-03116373864
GeneFamilyUbiquitin specific peptidases

USP26 USP8

5.85e-0356372366
CoexpressionGSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_DN

GIMAP4 OAS1 GIMAP7 LAP3 HELB

2.37e-05196465M4231
CoexpressionGSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_DN

GIMAP4 FRMD4A MYCBP2 LYST ZNF516

2.62e-05200465M9839
CoexpressionRUBENSTEIN_SKELETAL_MUSCLE_ENDOTHELIAL_CELLS

GIMAP4 ADGRF5 GIMAP7 LAP3

9.83e-05137464M41743
CoexpressionGSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

H1-5 H1-1 LAP3 NUBP2

2.11e-04167464M9116
CoexpressionACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_UP

MET EMC7 MYCBP2 LAP3

2.41e-04173464M2480
CoexpressionMOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN

MET RAN RUVBL2 LAP3

2.46e-04174464M17193
CoexpressionGRASEMANN_RETINOBLASTOMA_WITH_6P_AMPLIFICATION

RAN NUP153

2.71e-0414462M14308
CoexpressionBREUHAHN_GROWTH_FACTOR_SIGNALING_IN_LIVER_CANCER

MET AXIN1

3.12e-0415462M18219
CoexpressionUNTERMAN_IPF_VS_CTRL_TREG_CELL_UP

GIMAP4 GIMAP7

3.12e-0415462M48289
CoexpressionPEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2

LGR4 MET LYST

3.13e-0475463M2414
CoexpressionSANA_RESPONSE_TO_IFNG_UP

OAS1 GIMAP7 LAP3

3.25e-0476463M4551
CoexpressionGSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP

LGR4 VPS13D MYCBP2 H1-3

3.87e-04196464M3189
CoexpressionGSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN

GIMAP4 OAS1 FRMD4A GIMAP7

3.95e-04197464M8227
CoexpressionGSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_DN

OAS1 NUBPL ZNF516 H1-3

3.95e-04197464M9916
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_14_PRECICTIVE_ICB_RESPONSE

H1-5 H1-1 ADGRF5 H1-3

4.02e-04198464MM17083
CoexpressionGSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDC_DN

MET NUBP1 NUP153 HELB

4.10e-04199464M4036
CoexpressionGSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN

OAS1 MYCBP2 LYST SIPA1L1

4.10e-04199464M9846
CoexpressionGSE40273_XBP1_KO_VS_WT_TREG_DN

GIMAP4 GIMAP7 MYCBP2 LYST

4.10e-04199464M9124
CoexpressionGSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_UP

GIMAP7 LYST TMEM51 SIPA1L1

4.10e-04199464M5694
CoexpressionGSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP

OAS1 FRMD4A MYCBP2 LYST

4.18e-04200464M9489
CoexpressionGSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN

MET FRMD4A MYCBP2 LYST

4.18e-04200464M9328
CoexpressionGSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_DN

OAS1 INTS12 MYCBP2 LAP3

4.18e-04200464M7618
CoexpressionGSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN

EMC7 TENM4 LAP3 SIPA1L1

4.18e-04200464M6650
CoexpressionGSE18893_TCONV_VS_TREG_24H_CULTURE_UP

GIMAP4 GIMAP7 TMEM51 SIPA1L1

4.18e-04200464M7290
CoexpressionGSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_UP

MET NUBP1 RAN NUP153

4.18e-04200464M8638
CoexpressionGSE42724_NAIVE_VS_MEMORY_BCELL_UP

PLIN4 INTS12 PLP1 AGAP2

4.18e-04200464M9792
CoexpressionGSE17580_TREG_VS_TEFF_DN

ZDHHC5 LYST NUP153 AXIN1

4.18e-04200464M3671
CoexpressionGSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP

GIMAP4 GIMAP7 LYST SIPA1L1

4.18e-04200464M9205
CoexpressionGSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP

ZDHHC5 GIMAP4 VPS13D MYCBP2

4.18e-04200464M6096
CoexpressionAtlasalpha beta T cells, T.8Eff.Sp.OT1.d5.VSVOva, CD8+ CD45.1+, Spleen, avg-3

H1-5 GIMAP4 H1-1 GIMAP7

2.86e-0583454GSM538387_100
ToppCellMild-CD8+_T_activated|Mild / Disease group and Cell class

GIMAP4 OAS1 GIMAP7 LYST LAP3 HELB

5.45e-08198466ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

H1-5 OAS1 H1-1 GIMAP7 H1-3

5.22e-07153465c4dcdcaa672929c1da870e9fb8ada1bb030ad12f
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLIN4 GIMAP4 OAS1 ADGRF5 GIMAP7

1.10e-061784654ef6344d0ffc9c55b1240bee94b741382f1427bb
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLIN4 GIMAP4 OAS1 ADGRF5 GIMAP7

1.10e-06178465c65932cbedbbfacb6f0299280663fe7c88dba72b
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLIN4 GIMAP4 OAS1 ADGRF5 GIMAP7

1.33e-06185465fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

GIMAP4 OAS1 GIMAP7 LAP3 HELB

1.44e-061884656f8946d4710f6e32c937213f99b790b098b8819c
ToppCellCV-Moderate-1|Moderate / Virus stimulation, Condition and Cluster

GIMAP4 OAS1 GIMAP7 LYST LAP3

1.77e-06196465b50cfcd87c5b67806450cb8b3c6860ab97f6d3b1
ToppCellMild-CD4+_T_activated|Mild / Disease group and Cell class

GIMAP4 OAS1 GIMAP7 LAP3 HELB

1.77e-06196465daa1c3322d81e649161e889e1d78451d2d425d09
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

H1-5 RAN H1-1 PLP1 H1-3

1.77e-061964654924a36a81d62863c1004b8c76f8096a1f89c548
ToppCellCD8+_Memory_T_cell-CV-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

GIMAP4 OAS1 GIMAP7 LYST LAP3

1.81e-06197465e59b47bccc781b2117196fe322efa87559c237c6
ToppCellCV-Mild-1|CV / Virus stimulation, Condition and Cluster

GIMAP4 OAS1 GIMAP7 LAP3 HELB

1.86e-061984654b078714c49e7befb7b113d72485e712236d35fa
ToppCelltumor_Lung-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

GIMAP4 FRMD4A GIMAP7 LYST

1.40e-05142464eaf08a0dbacc9ebbd54e377922e76d8ba854dcb8
ToppCellIIH-CD4-antiviral_CD4|IIH / Condition, Cell_class and T cell subcluster

GIMAP4 OAS1 GIMAP7 H1-3

1.65e-05148464ec626a44cea83f2a0e5c27fc8182f96446d297ac
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD8-Trm/em_CD8|GI_large-bowel / Manually curated celltypes from each tissue

GIMAP4 GIMAP7 LYST HELB

2.08e-05157464d85304af4cd3b8aaedc5362a8223537e1b9dbec2
ToppCellmild-Myeloid-CD14_Monocytes_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

GIMAP4 GIMAP7 LAP3 TMEM51

2.24e-05160464a83568cd8a0b05642bacd43a8ec443e5ce314c4d
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PLIN4 MET ABCC9 ADGRF5

2.35e-051624642259e9536147e9cdee772e3a30ba7d104573262c
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PLIN4 MET ABCC9 ADGRF5

2.58e-0516646489e2b8453180983533faccb4275867861876d7ee
ToppCelldroplet-Fat-Mat-18m-Lymphocytic-lymphocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 HERC3 GIMAP7 AGAP2

2.97e-05172464226de1a5d4a360d3ae01b0235fea19521ec623a0
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

H1-5 GIMAP7 AGAP2 H1-3

2.97e-05172464282017db72d0537ac82aecc69393ccde9590be60
ToppCellRSV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

GIMAP4 OAS1 LAP3 AGAP2

3.18e-05175464ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCellRSV-Healthy-1|RSV / Virus stimulation, Condition and Cluster

GIMAP4 OAS1 LAP3 AGAP2

3.18e-05175464ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

H1-5 RAN H1-1 H1-3

3.25e-051764649e719e6323597ecfc758c957256872cd4ae24d4d
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

PLIN4 FRMD4A TENM4 MYCBP2

3.39e-05178464278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MUC19 GIMAP4 ADGRF5 GIMAP7

3.39e-05178464c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-Activated_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIMAP4 H1-1 GIMAP7 HELB

3.47e-0517946402218c048e4dec0c0a3d63d2abb4feb4c3e82697
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GIMAP4 MET ADGRF5 GIMAP7

3.55e-051804645861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIMAP4 ADGRF5 LOXHD1 GIMAP7

3.62e-051814644a225d9a6d113396c6b1d0a839bb4ca9c339a260
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 GIMAP7 MYCBP2 LYST

3.70e-05182464e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 GIMAP7 MYCBP2 LYST

3.70e-051824641710eab3037a87609d21838be2d2d29c3bc36651
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

PLIN4 FRMD4A TENM4 MYCBP2

3.78e-051834643f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MUC19 GIMAP4 ADGRF5 GIMAP7

3.86e-05184464a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

ZDHHC5 MET LYST AXIN1

3.86e-05184464d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIMAP4 ADGRF5 LOXHD1 IBSP

3.95e-05185464602536a3308a848f106adcb0a83530997440c8f4
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GIMAP4 OAS1 ADGRF5 GIMAP7

4.03e-0518646486b218a400f9c64f92b050f00b49f09647b17437
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

H1-5 H1-1 PLP1 H1-3

4.03e-0518646415ab6666748a641226e42e6ca6eeaf186a501c95
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GIMAP4 OAS1 ADGRF5 GIMAP7

4.03e-05186464f51c76b1c3c6c49e0ebc9a913d8413e0b6a04d80
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIMAP4 OAS1 ADGRF5 GIMAP7

4.03e-051864649d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

H1-5 H1-1 PLP1 H1-3

4.03e-051864644ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GIMAP4 OAS1 GIMAP7 LAP3

4.11e-0518746472e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GIMAP4 OAS1 ADGRF5 GIMAP7

4.11e-0518746403de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

GIMAP4 GIMAP7 ANKRD36C HELB

4.20e-05188464b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MUC19 GIMAP4 ADGRF5 GIMAP7

4.20e-05188464b66f1f08827dd6c48583d871f9f33ea41e48bfb2
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

H1-5 H1-1 PLP1 H1-3

4.20e-0518846433afe31b1093d317dc38c324197c6e91bf6c39d3
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

PLIN4 FRMD4A TENM4 MYCBP2

4.20e-051884644dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCellwk_08-11-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PLIN4 GIMAP4 OAS1 GIMAP7

4.38e-05190464279c5f68b993dc7adbf9aa69fffb1321cdebc48a
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MUC19 GIMAP4 MET ADGRF5

4.38e-051904641307688255a1250fa300edf2c41f1affe31dcc98
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GIMAP4 BPTF ADGRF5 MYCBP2

4.38e-05190464d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellwk_08-11-Endothelial-Lymph_endothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PLIN4 GIMAP4 OAS1 GIMAP7

4.38e-05190464d7f1dc032d161529559e01832d1a3112c6f6cc1a
ToppCellNS-critical-d_07-13-Lymphoid-Treg|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GIMAP4 GIMAP7 AGAP2 H1-3

4.56e-05192464cd34defac6565d34db507918e791b09c79f7d1f8
ToppCellCV-Healthy-1|CV / Virus stimulation, Condition and Cluster

GIMAP4 OAS1 GIMAP7 LAP3

4.56e-05192464934d2e6a65121b24b91d386f7940fb9c1a7357ab
ToppCellCOVID-19-Myeloid-MoAM1,_IL1R2|Myeloid / Condition, Lineage and Cell class

GIMAP4 OAS1 GIMAP7 LAP3

4.56e-05192464be9d5685fa03563322f147a4b38ed31e4da59487
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GIMAP4 ADGRF5 LOXHD1 GIMAP7

4.65e-05193464d338a7c0585b69947c37f44aa0381619493e31ea
ToppCelldroplet-Bladder-nan-3m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 FRMD4A ABCC9 ADGRF5

4.65e-051934648be24713f8ba2545b7647d1994e9e993623ddaa3
ToppCelldroplet-Bladder-nan-3m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 FRMD4A ABCC9 ADGRF5

4.65e-0519346419dfc4a2c91fcea4f5991e7c44df46faeecb06b8
ToppCelldroplet-Bladder-nan-3m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP4 FRMD4A ABCC9 ADGRF5

4.65e-05193464351e0acd411a9eb0dbc0e358d0d1e3759753fa40
ToppCellLeuk-UTI|World / Disease, Lineage and Cell Type

GIMAP4 OAS1 GIMAP7 LAP3

4.65e-0519346426119a0b5d7684022fd16b8b73a0ef5a7d70f3d1
ToppCellPCW_07-8.5|World / Celltypes from embryonic and fetal-stage human lung

H1-5 H1-1 TENM4 H1-3

4.75e-051944645759c83308df017f1faae248e9b85388e25254f0
ToppCell3'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLIN4 GIMAP4 ADGRF5 GIMAP7

4.75e-05194464622461e5f9c648252a2f6ec84e7565220a803132
ToppCellfacs-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

H1-5 H1-1 LYST H1-3

4.84e-0519546479114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GIMAP4 ADGRF5 GIMAP7 LAP3

4.84e-0519546475db19c0371320ea5fce1d6de8c1b40b1e6a2e58
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIMAP4 ADGRF5 LOXHD1 GIMAP7

4.94e-051964649b53e3fdb23dbdfc2e7ce012c6b2ce50700c95d5
ToppCell5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIMAP4 MET ADGRF5 LAP3

5.04e-0519746461b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCellCV-Moderate-1|CV / Virus stimulation, Condition and Cluster

GIMAP4 OAS1 GIMAP7 LAP3

5.04e-05197464e3d00d850b4d191f9592ef993c0eaadfe5710b5f
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GIMAP4 GIMAP7 HELB H1-3

5.04e-05197464e60deb009238702110c3b0948778802df215ad74
ToppCellSevere_COVID-19|World / Disease group,lineage and cell class （2021.01.30）

GIMAP4 OAS1 GIMAP7 LAP3

5.14e-0519846409fd456077bb3a657ad3b10c6cfe799b7266456a
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GIMAP4 ADGRF5 GIMAP7 LAP3

5.14e-0519846440c2171e79f578c9116d872c189f953dc61d052d
ToppCellBAL-Severe|BAL / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GIMAP4 OAS1 GIMAP7 LAP3

5.14e-05198464454aee3f4fe6d0beeccc55200b4495f4f9b44feb
ToppCellBAL-Severe|BAL / Compartment, Disease Groups and Clusters

GIMAP4 OAS1 GIMAP7 LAP3

5.14e-05198464f63cfcc57f46094ea0673bbc70ea443ebaca6176
ToppCellBAL-Severe|BAL / Location, Disease Group, Cell group, Cell class (2021.03.09)

GIMAP4 OAS1 GIMAP7 LAP3

5.14e-05198464687f69c16343227854c882b4a0f3930ce534a3d2
ToppCellNon-neuronal-Postmitotic-Endothelial|World / Primary Cells by Cluster

GIMAP4 ABCC9 ADGRF5 GIMAP7

5.24e-05199464b9763ac9857a60db6f1f104fe1e9ea2266cf931b
ToppCellNon-neuronal-Postmitotic-Endothelial-Endothelial-24|World / Primary Cells by Cluster

GIMAP4 ABCC9 ADGRF5 GIMAP7

5.24e-051994640b4edf3e359749827ef978a77b5267ddde732d71
ToppCellCaecum-(1)_T_cell-(16)_Tfh|Caecum / shred on region, Cell_type, and subtype

H1-5 GIMAP4 GIMAP7 H1-3

5.24e-05199464d07d77ae426dd1164d80d7031f14befa0369d3e5
ToppCellNon-neuronal-Postmitotic-Endothelial-Endothelial|World / Primary Cells by Cluster

GIMAP4 ABCC9 ADGRF5 GIMAP7

5.24e-051994649e01eee126247a0696c71b019f855a8a41a0ede3
ToppCellVE-CD4-antiviral_CD4|VE / Condition, Cell_class and T cell subcluster

GIMAP4 OAS1 GIMAP7 LAP3

5.24e-05199464056a0538ca5e825ae6195b4c76c208708a014533
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIMAP4 ADGRF5 LOXHD1 GIMAP7

5.24e-051994640d63da0afa93741c37609d879941de202d9ac86c
ToppCellCaecum-T_cell-Tfh|Caecum / Region, Cell class and subclass

H1-5 GIMAP4 GIMAP7 H1-3

5.24e-05199464fb40f37d842f170ed101dfa3bffdb8f3b2c94f19
ToppCellPBMC-Severe-cDC_9|Severe / Compartment, Disease Groups and Clusters

GIMAP4 OAS1 LAP3 H1-3

5.34e-05200464ea3b22126d9dfd158bb3c3e1323b30514d721ded
ToppCellControl-Control-Lymphocyte-T/NK-dn_T|Control / Disease, condition lineage and cell class

GIMAP4 MET FRMD4A LYST

5.34e-0520046410882c59b7aaf8bd4b5c00aa4ddbb9f7ac5b2cf5
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

GIMAP4 OAS1 ADGRF5 LAP3

5.34e-05200464edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

GIMAP4 OAS1 ADGRF5 LAP3

5.34e-0520046489821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellVE|World / Condition, Cell_class and T cell subcluster

BPTF OAS1 MYCBP2 H1-3

5.34e-052004648ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

H1-5 RAN H1-1 H1-3

5.34e-052004644923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

H1-5 RAN H1-1 H1-3

5.34e-05200464dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellmoderate-Lymphoid-NKT-proliferating|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

H1-5 RAN H1-1 H1-3

5.34e-052004648692e6664f0bb2be990f7563888380bb47414626
ToppCell367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GIMAP4 KRT1 GIMAP7

8.99e-0584463fedccab997a8ca298b97240e1db1683cdf56140b
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B1|390C / Donor, Lineage, Cell class and subclass (all cells)

GIMAP4 GIMAP7 ANKRD36C

2.05e-041114639972d31966b059aa3446407b73b714b0b06ec815
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCC9 ADGRF5 TMEM51

2.71e-04122463c16110934172f174f4aefe14b81abce8514b30f0
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell-Peri|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCC9 ADGRF5 TMEM51

2.71e-04122463006ac4f6807e688554d36557d29d5e5a0bc3c36f
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCC9 ADGRF5 TMEM51

2.71e-04122463f3d9a5893fdee3562880fb6fc132b88169a7d997
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

H1-5 H1-1 H1-3

3.12e-041284639ab55a0421cd970e0b8dabce67dd68e382a6bd41
ToppCellmoderate-Epithelial-unknown_epithelial|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

H1-5 H1-1 ANKRD36C

3.27e-04130463a04057bd4f256d09eca06b8c1e8b41425bb4ef3f
ToppCell21-Trachea-Immune-Immune|Trachea / Age, Tissue, Lineage and Cell class

MUC19 KRT1 HELB

3.57e-041344634f0465324cc5b443ebadb68aef63be79b74f6ff9
ToppCellLPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_only / Treatment groups by lineage, cell group, cell type

H1-5 FRMD4A H1-3

3.89e-041384636ddd50e44a3914596b4cd61ae64a987119fe7979
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)|Thalamus / BrainAtlas - Mouse McCarroll V32

GIMAP4 H1-1 HELB

4.23e-0414246358bfff3284ae21150e4619511bd58622c16c5dde
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)--|Thalamus / BrainAtlas - Mouse McCarroll V32

GIMAP4 H1-1 HELB

4.23e-041424635fd737c1fee9d97aee8955f1bf378ead3fce138d
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)-|Thalamus / BrainAtlas - Mouse McCarroll V32

GIMAP4 H1-1 HELB

4.23e-0414246316f9945e835c3506b12d904778560d065a50f059
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCC9 GIMAP7 HELB

4.32e-04143463eb11ff288cb91210383b288aa57715ebd59a52c3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRF5 LOXHD1 EML6

4.59e-04146463e887e9de895fd453faa703997ef372cc6410fc49
ToppCellcontrol-dn_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GIMAP4 MET GIMAP7

4.68e-0414746368258498202c7f580f72c46dd645071835098455
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

OAS1 ABCC9 HELB

4.96e-041504636c39e73a0b05d4b26589f333ce13924e3d373b8d
Diseasecontactin-1 measurement

MUC19 AXIN1

3.40e-056452EFO_0020286
DiseaseHEPATOCELLULAR CARCINOMA

MET AXIN1

8.13e-059452114550
DiseaseHepatocellular carcinoma

MET AXIN1

8.13e-059452cv:C2239176
Diseaseoral squamous cell carcinoma (is_marker_for)

MET AXIN1 AGAP2

1.23e-0463453DOID:0050866 (is_marker_for)
Diseasephosphoglyceric acid measurement

NUBP1 NUBP2

3.05e-0417452EFO_0010523
DiseaseSquamous cell carcinoma

KRT1 MET SIRT3

9.04e-04124453C0007137

Protein segments in the cluster

PeptideGeneStartEntry
RPGKGGSVFSSTTQK

USP26

111

Q9BXU7
SKSFEIAKGSGTGVL

USP26

141

Q9BXU7
VSKGTLVQTKGTGAS

H1-1

91

Q02539
KTVTTSGAKAGGGKG

AGAP2

191

Q99490
VKGSKSSAGTGASVS

AGAP2

221

Q99490
KVGICGRTGSGKSSL

ABCC9

1341

O60706
EGGIKGIGKTSTNSS

BPTF

1211

Q12830
SGKGGVGKSTISTEL

NUBP2

21

Q9Y5Y2
FKLVLVGDGGTGKTT

RAN

11

P62826
LATSSKGGIGSKIGS

INTS12

336

Q96CB8
SGKGGVGKSTFSAHL

NUBP1

61

P53384
RITGGGKSGTVSSQK

ANKRD36C

671

Q5JPF3
GKGITFDSGGISIKA

LAP3

281

P28838
VLTKSGGVFTFGAGS

HERC3

256

Q15034
TVFTGDVRGAGTKSK

LOXHD1

301

Q8IVV2
GGVKSSGGSSSVKFV

KRT1

621

P04264
KTGLSAGVTGKTGLS

MUC19

3366

Q7Z5P9
GETGKIGSSAGVTGK

MUC19

3661

Q7Z5P9
GVTGKTGSSARVTGK

MUC19

3671

Q7Z5P9
ATGITGLSAGVTGKT

MUC19

4001

Q7Z5P9
SAGVTGTIGSSAGVK

MUC19

5816

Q7Z5P9
KSGLSAGVTGKTGLS

MUC19

5991

Q7Z5P9
SLGGSGTTGAKIKLV

MUC19

7111

Q7Z5P9
GTTGAKIKLVGTTTT

MUC19

7116

Q7Z5P9
GTSGTGFKIAGITSA

MUC19

7216

Q7Z5P9
STKGTGTSGTGFKTG

MUC19

7381

Q7Z5P9
KSGATSGVPGSKTGT

MUC19

7446

Q7Z5P9
KSGATTGAPGSKTGT

MUC19

7736

Q7Z5P9
TGAPGSKTGTAKVLS

MUC19

7741

Q7Z5P9
KKSGSVSVSISSQGG

LGR4

821

Q9BXB1
SKVVKGGSSGKGTTL

OAS1

56

P00973
KGKTGVSFALGISTV

MGAT4D

126

A6NG13
GSKGKIISGSSGSLL

FRMD4A

356

Q9P2Q2
VSKGTLVQTKGTGAS

H1-5

91

P16401
SGKGVGIKGETSTAT

AXIN1

46

O15169
GKIGIFESPTGTGKS

DDX12P

56

Q92771
EGFKVSIGSSKASGS

LYST

2711

Q99698
TSKRGTFGSVGKLET

EML6

851

Q6ZMW3
SSSGSSKTGKSGAGK

EMC7

226

Q9NPA0
KGTLVQTKGTGASGS

H1-3

91

P16402
TVISGKGGCGKTTIV

HELB

471

Q8NG08
VVASGKGGVGKSTTA

NUBPL

71

Q8TB37
KSFISGGSTITGVGK

MET

751

P08581
GTKNTLGSGVTGAAK

PLIN4

846

Q96Q06
ATGTGSKVGKLTLKT

RUVBL2

151

Q9Y230
VGKTGAGKSATGNSI

GIMAP4

36

Q9NUV9
IVLVGKTGSGKSATA

GIMAP7

11

Q8NHV1
TKLSDFLITGGGKGS

SIPA1L1

241

O43166
GKGTSKTTTSPNGGF

IBSP

221

P21815
VVGSGGSSDKGKLSL

SIRT3

111

Q9NTG7
LKAKGTTITGTAGTT

MYCBP2

4121

O75592
TTITGTAGTTVGKGV

MYCBP2

4126

O75592
KGVTVTGFKSGSVVV

ADGRF5

216

Q8IZF2
GSKSGSSPLGVVTKA

ZNF516

846

Q92618
TEVGGGILKSKTFSV

TMEM51

51

Q9NW97
TKKFASSGSVFGKGV

TENM4

2556

Q6N022
NKSGKTTLSASGTGF

NUP153

701

P49790
TRGGVKKVSGVGGTT

ZDHHC5

696

Q9C0B5
TSVTGDSGSGKPFKI

USP8

591

P40818
FISGLGKGLVGTVTK

VPS13D

4181

Q5THJ4
TTICGKGLSATVTGG

PLP1

106

P60201