Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentinterphotoreceptor matrix

EYS VCAN

7.70e-056482GO:0033165
DomainRetinoicA-induced_16-like

FHIP1B FHIP1A

3.87e-054482IPR019384
DomainRAI16-like

FHIP1B FHIP1A

3.87e-054482PF10257
DomainC-type_lectin_CS

PLA2R1 VCAN

5.46e-0343482IPR018378
Pubmed

Effects of complete vagotomy and blockage of cell adhesion molecules on interferon-α induced behavioral changes in mice.

ALCAM ITGB2

6.07e-06350223178534
Pubmed

Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.

DPYSL2 MTHFD1

3.03e-05650226792863
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

FAM114A1 DPYSL2 APPL2 RUVBL1 NRDC PDLIM1 MTHFD1 PSMD2 TP53RK CHORDC1

3.54e-051455501022863883
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PLA2R1 DPYSL2 RUVBL1 PDLIM1 EMG1 PSMD2 UTP20 ALCAM CHORDC1

4.74e-05120150935696571
Pubmed

The small-subunit processome is a ribosome assembly intermediate.

EMG1 UTP20

5.64e-05850215590835
Pubmed

Expression of testicular germ cell genes identified by differential display analysis.

ANKRD18A ANKRD18B

5.64e-05850212634303
Pubmed

Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription.

APPL2 RUVBL1

5.64e-05850219433865
Pubmed

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.

RUVBL1 MTHFD1 RBM10 CHORDC1

7.64e-0515650437108203
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

DPYSL2 FRY PDLIM1 MTHFD1 UTP20 ANKRD18A TMEM132B

8.37e-0573650729676528
Pubmed

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.

DPYSL2 PDLIM1 MTHFD1 PSMD2 CHORDC1

8.96e-0531550526777405
Pubmed

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.

DPYSL2 RUVBL1 MTHFD1 PSMD2

9.71e-0516650435687106
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RUVBL1 PDLIM1 MYO5B MTHFD1 RBM10 EMG1 PSMD2 UTP20

9.85e-05102450824711643
Pubmed

Quantitative interaction proteomics of neurodegenerative disease proteins.

HAUS4 RUVBL1 MTHFD1 PSMD2 CHORDC1

1.01e-0432350525959826
Pubmed

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.

DPYSL2 RUVBL1 MTHFD1 PSMD2 ALCAM ITGB2

1.55e-0456550620458337
Pubmed

Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes.

MYO5B FHIP1B FHIP1A

1.55e-047250334882091
Pubmed

The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A.

FHIP1B FHIP1A

1.56e-041350232073997
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DPYSL2 APPL2 NRDC MYO5B MTHFD1 VCAN PSMD2 RAPGEF2 BSN

1.80e-04143150937142655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

OR1M1 FAM114A1 KIAA0825 MYO5B PSMD2 ALCAM BSN DNAH8 MYBPC2

1.90e-04144250935575683
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

DPYSL2 HAUS4 RUVBL1 PDLIM1 CHORDC1 FHIP1B FHIP1A

2.08e-0485350728718761
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

DPYSL2 VPS13D MTHFD1 VCAN

3.67e-0423550430258100
Pubmed

The RNA-binding protein Snd1/Tudor-SN regulates hypoxia-responsive gene expression.

RUVBL1 PDLIM1 CHORDC1

3.75e-049750337151849
Pubmed

Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

VPS13D UBE3D MTHFD1 EMG1 UTP20

4.84e-0445450533226137
Pubmed

Identification of FBXO25-interacting proteins using an integrated proteomics approach.

RUVBL1 MTHFD1 PSMD2

5.71e-0411250320473970
Pubmed

Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.

RUVBL1 MTHFD1 RBM10 PSMD2

6.09e-0426950430442662
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

RUVBL1 MYO5B RBM10 PSMD2

6.35e-0427250431010829
Pubmed

Antiviral inhibition targeting the HCMV kinase pUL97 requires pUL27-dependent degradation of Tip60 acetyltransferase and cell-cycle arrest.

RUVBL1 PSMD2

6.95e-042750221320693
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

FAM114A1 APPL2 TP53RK CHORDC1 MYBPC2

7.29e-0449750523414517
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

APPL2 AKAP11 FHIP1A

7.85e-0412550329467281
Pubmed

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.

DPYSL2 RUVBL1 MTHFD1 PSMD2

1.06e-0331250437120454
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

DPYSL2 RUVBL1 PDLIM1 RBM10 CHORDC1

1.14e-0354950538280479
Pubmed

Thioredoxin interacting protein (Txnip) forms redox sensitive high molecular weight nucleoprotein complexes.

RUVBL1 RBM10

1.24e-033650231669268
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

DPYSL2 VPS13D GUCY2C VCAN MYBPC2

1.28e-0356450521565611
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

FAM114A1 DPYSL2 VPS13D PDLIM1 CHORDC1

1.32e-0356850537774976
Pubmed

A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair.

MTHFD1 PSMD2 ALCAM

1.41e-0315350327462432
Cytoband1p22.3

DNAI3 SPATA1

2.65e-04225021p22.3
Cytoband4p14

FAM114A1 KLB

9.73e-04425024p14
CytobandEnsembl 112 genes in cytogenetic band chr4p14

FAM114A1 KLB

2.46e-0367502chr4p14
ToppCellCOVID-19-kidney-Technical/muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

EYS TEX15 DNAH8 TMEM132B

1.80e-0513950413247bcb21c57c808657e0f543d6f134eeea7cc1
ToppCellCOVID-19-kidney-Technical/muscle|kidney / Disease (COVID-19 only), tissue and cell type

EYS TEX15 DNAH8 TMEM132B

2.30e-051485040dbd87078f54ee1c2f8ec64e8bac9dfddb9c181e
ToppCellLPS-antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5B UTP20 FHIP1A SPATA1

2.43e-051505049cb3332924bd67c966873343c14445e30d3f384f
ToppCell3'_v3-blood-Lymphocytic_B-ABC_aged-B_memory|blood / Manually curated celltypes from each tissue

PDLIM1 GUCY2C ACP5 DNAH8

3.78e-051685042ce1a30feb2704a9516d1dab161a26cb0555abb5
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5B MTHFD1 ALCAM TEX15

4.43e-05175504442f261a3b2c4d2523f7d4089178f8c79cac2f0f
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5B MTHFD1 ALCAM TEX15

4.43e-0517550435fb7735dd3355476fe60404833cb60bd066bcf1
ToppCellCOVID-19_Moderate-B_intermediate|COVID-19_Moderate / disease group, cell group and cell class

PDLIM1 GUCY2C ACP5 DNAH8

4.63e-0517750468e3d12a0c048a2d0f1b9680c7338a35855bba30
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5B MTHFD1 ALCAM TEX15

4.63e-05177504a68c3688f12aee22f3cb4049c4bccacbacb0fae6
ToppCellB_cells-ABCs|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

DPYSL2 ACP5 ITGB2 DNAH8

5.27e-05183504bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCellMild/Remission-B_intermediate-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DPYSL2 ACP5 ITGB2 DNAH8

5.38e-051845043d4864605c812862cf8926e02370eea3b8ccf32f
ToppCellPND01-03-samps-Epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MYO5B MTHFD1 ALCAM TEX15

5.50e-051855042b854df79cfe2cb4d2f9c2938a066e0aa3649325
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MYO5B MTHFD1 ALCAM TEX15

5.73e-0518750423fe3cdd6cc9b067086a8392d104186d300298ea
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FRY MYO5B ALCAM FHIP1A

5.85e-05188504beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDLIM1 GUCY2C ACP5 DNAH8

6.22e-051915046a8b0987e75456a257954288206da0032605ff2a
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FRY ANKRD18A ALCAM FHIP1A

6.22e-0519150463aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCellVE-naiveBc-|VE / Condition, Cell_class and T cell subcluster

PDLIM1 GUCY2C ACP5 DNAH8

6.35e-05192504bca2aec4811627225fccd92abe2f3b1ba729c9ce
ToppCellVE-naiveBc|VE / Condition, Cell_class and T cell subcluster

PDLIM1 GUCY2C ACP5 DNAH8

6.35e-0519250487cdda9a170f6f2fa56d0ed1d3fd2f93bfe09aa1
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FRY MYO5B ALCAM FHIP1A

6.74e-05195504d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCellNS-critical-d_07-13-Myeloid-Non-resident_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DPYSL2 VCAN ACP5 ITGB2

6.74e-05195504ee8743d39996bb756f50db32748e8a902d3294b8
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DPYSL2 VCAN ALCAM ITGB2

6.88e-0519650428e9e191361966df3a9bd48450090577aa72a999
ToppCelldistal-1-Hematologic-Interstitial_Macrophage|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VCAN ACP5 ALCAM ITGB2

7.01e-051975049e5df74aeeefa4d928ec07c036aacb549c797f30
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DPYSL2 VCAN ACP5 ALCAM

7.01e-051975047293587c875738c1711b8a68d40303a197b01c32
ToppCellMild/Remission-B_intermediate-6|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DPYSL2 ACP5 ITGB2 DNAH8

7.01e-051975045370dda4a25e3a53d6fe2c887b7dabd7a58462b4
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DPYSL2 VCAN ACP5 ALCAM

7.01e-0519750482072bd73634e1ef24dc193e860af7786727313b
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DPYSL2 VCAN ACP5 ALCAM

7.01e-05197504b4869013f0523ac73c284e6cdaf64e9ae5213dc5
ToppCellPCW_13-14-Epithelial|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FRY MYO5B ALCAM FHIP1A

7.15e-0519850448eb6f69a464a34ab32e8d425a22b9d45ec20428
ToppCellTransplant_Alveoli_and_parenchyma|World / Tissue, Lineage and Cell class of Lung Cells from 10X

DPYSL2 VCAN ACP5 ITGB2

7.29e-0519950444bd36a62f06058c5d09feec6e96ecaf310f4791
ToppCellBronchial-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

VCAN ACP5 ITGB2 DNAH8

7.29e-05199504a1ff1063741f6e5569feb44245785c9f472799b2
ToppCellcritical-Myeloid-Non-resident_Macrophage|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DPYSL2 VCAN ACP5 ITGB2

7.29e-05199504193325768b17d3123ae855317f381a01088b5dac
ToppCell3'_v3-Lung-Myeloid_Mac|Lung / Manually curated celltypes from each tissue

DPYSL2 PDLIM1 ACP5 ALCAM

7.29e-051995041677aaee5b7f5f262e27df5d9f1bdf6e21e3d804
ToppCellCOVID-19-Myeloid-MoAM3,_VCAN|COVID-19 / Condition, Lineage and Cell class

VCAN ACP5 ALCAM ITGB2

7.29e-05199504aba0b833e44fe42625fac91466f6ebaa8e786d3b
ToppCellControl-Control-Lymphocyte-B-B_memory|Control / Disease, condition lineage and cell class

PDLIM1 GUCY2C ACP5 DNAH8

7.29e-0519950476976d5f79f324a6c488161847c50f207361d6c6
ToppCell3'_v3-Lung-Myeloid_Mac-Alveolar_macrophages|Lung / Manually curated celltypes from each tissue

DPYSL2 PDLIM1 ACP5 ALCAM

7.29e-05199504eec1b086e5e8b9b0e1770dd269ca903f713d99a8
ToppCellCOVID-19-Myeloid-MoAM3,_VCAN|Myeloid / Condition, Lineage and Cell class

VCAN ACP5 ALCAM ITGB2

7.29e-0519950480f70c53e892fb692ef655662732e16e2c03ac8e
ToppCellBronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

VCAN ACP5 ALCAM ITGB2

7.44e-05200504c30da72c3581d384b76c95f5989e32a36d783ef3
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

VCAN ACP5 ALCAM ITGB2

7.44e-0520050409bac15df511687ff336c1e7a67d980c6c281f79
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

UBE3D DNAH8 FHIP1A

2.85e-041145032cc5d2da5573650c5232a01e2d2128082c4bffcb
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

UBE3D DNAH8 FHIP1A

2.85e-04114503fceb7cc590a47380145fc0d854c9f2350dbb0a59
ToppCellControl-B_memory-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ACP5 DNAI3 DNAH8

3.64e-041245033e987915026f503e8d072a837b6e7a34252e5c63
ToppCellmild-Myeloid-CD14_Monocytes_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

GUCY2C VCAN CLUL1

4.00e-041285037a0a7af930e9050d473390fe9827f96fd597f790
ToppCellmild-Myeloid-CD14_Monocytes_2|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

GUCY2C VCAN CLUL1

4.57e-041345038ba1f8d0af63bb7a802a002e72fe181b203cb451
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

EYS VPS13D VCAN

4.67e-041355033351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCellControl-B_memory-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MTHFD1 ACP5 DNAH8

4.77e-0413650394f23bef50c0beb54ed39b1a4b340f7aec4e75cd
ToppCellLPS-antiTNF-Endothelial-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UTP20 FHIP1A SPATA1

5.64e-0414450375b16adfbe84f69376e6566d531ba7919d5c5192
ToppCellEpithelial-B_(AT1-AT2-progenitors)|World / shred on cell class and cell subclass (v4)

MTHFD1 ALCAM TEX15

5.87e-041465034511916904c1fac252cb68e871b782207f8137b3
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

EYS DNAH8 TMEM132B

6.10e-04148503d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC10A1 PSMD2 BSN

6.22e-0414950361d84838a841ed2d6b8c5f86d423a4e6b3dcc9cb
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDLIM1 ACP5 DNAH8

6.22e-041495032cd860b96ed4be4d26844085d464961c1418054a
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RUVBL1 PDLIM1 ACP5

6.72e-041535039f0607a88d5f8a2c128a2ff64dfbc986212f13b2
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VCAN ACP5 ALCAM

6.85e-041545031e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EYS GUCY2C KLB

6.98e-04155503498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

EYS DNAH8 TMEM132B

7.51e-041595035335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_Cytotoxic_T_cells|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDLIM1 ITGB2 FHIP1A

7.51e-041595032060e7ed5627976b48fea4a2328762b6fa308db1
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

PDLIM1 BSN FHIP1A

7.65e-04160503731def6d82814ebac1a400bc7aea5f6da43ec960
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

PDLIM1 BSN FHIP1A

7.65e-04160503cf27b4ac4d0caa6f9b068dc8ea93472470a01a4d
ToppCellMild-MAIT|Mild / Disease group and Cell class

FRY VCAN FHIP1A

7.79e-041615030c1a04485708d5302600cdc2d7dac1cb76b4033a
ToppCelltumor_Lung-Myeloid_cells-Pleural_Mac|tumor_Lung / Location, Cell class and cell subclass

DPYSL2 VCAN ITGB2

7.93e-041625039ac3242511315224ed94582aca9e9a3786cd01a0
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO5B MFSD6L ALCAM

7.93e-041625035c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDLIM1 ANKRD18A FHIP1A

8.07e-04163503d7057ae155058a13f3d7c3db5c7fbc3bb2b69376
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDLIM1 ANKRD18A FHIP1A

8.07e-0416350355fd4f21c7a8bea031fb6f7f2c8cc1ff42b00d79
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|343B / Donor, Lineage, Cell class and subclass (all cells)

VCAN ACP5 ALCAM

8.22e-04164503057ca87847373eff7fe97dd9f4358509e66ca4c3
ToppCellsevere-unassigned|severe / disease stage, cell group and cell class

MTHFD1 ZMYM1 SPATA1

8.36e-04165503f9ddd547992fec065d539a1d0305acba8fc7d79c
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MFSD6L ALCAM FHIP1A

8.36e-04165503f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCellMild/Remission-B_memory-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ACP5 ITGB2 DNAH8

8.51e-0416650303e1a369d8a83b814def07e29cabb023226b4828
ToppCellmild_COVID-19_(asymptomatic)-B_intermediate|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

SLC10A1 GUCY2C DNAH8

8.51e-041665038de8f388f24436b84e19ef460476fdbda4d16abf
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDLIM1 ALCAM FHIP1A

8.51e-0416650301544c851588f1cde05d6700c3d1167f70a0fbd5
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MFSD6L ALCAM TEX15

8.51e-04166503575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDLIM1 ALCAM FHIP1A

8.51e-04166503c22a97353f7eb084f768c13d7767a80b30f05043
ToppCell10x5'-Liver-Myeloid_Dendritic-pDC|Liver / Manually curated celltypes from each tissue

ALCAM TMEM132B FHIP1A

8.51e-0416650324dfa9f3e0842f9ab8350bf6a52ae0d10f2a0c44
ToppCellCV-Mild-6|CV / Virus stimulation, Condition and Cluster

UBE3D ACP5 TP53RK

8.66e-04167503cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCellIIH-naiveBc|IIH / Condition, Cell_class and T cell subcluster

PDLIM1 GUCY2C ACP5

8.81e-041685038450ed6720d308c711dfbc76652e5821be7b8e93
ToppCellIIH-naiveBc-|IIH / Condition, Cell_class and T cell subcluster

PDLIM1 GUCY2C ACP5

8.81e-0416850327b500f79aedc4669988670c92ff1a47dcbdf2a0
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EYS BSN KLB

9.12e-0417050302f0be0aab8ba2d35a83238609352ef3677511c9
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL2 ALCAM ITGB2

9.27e-041715030385d5834ae16bbb0c6a68893fec60e4dd1e478d
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL2 ALCAM ITGB2

9.27e-04171503a3e3fe0cbab21abb178c482f5951e576529f7e30
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5B MTHFD1 ALCAM

9.59e-0417350345808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

APPL2 MYO5B VCAN

9.59e-0417350342c911ed16fabdabef063830e8407192d8bde950
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5B MTHFD1 ALCAM

9.59e-041735037fa9dbcb258c3ab974490063951620e2def03db1
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDLIM1 ALCAM FHIP1A

9.59e-04173503b002b22f9968b5967d29fe0eab4e796d87b355fa
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP11 BSN FAM135A

9.75e-04174503f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VCAN ACP5 ITGB2

9.75e-04174503d5c22b43531414951666ee7542a66ed9380e2d14
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid-new-cluster|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5B ALCAM ITGB2

9.75e-04174503718e14d9a4264456459bec4c062c94c3a848d43a
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDLIM1 ACP5 DNAH8

9.91e-041755031b3510e9078eec7cfc5805043e435e9e5e0f0877
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5B MTHFD1 TEX15

9.91e-0417550396219e58dcb327fd27190be78193e7a0d611e62b
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5B MTHFD1 TEX15

9.91e-04175503cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5B ALCAM ITGB2

9.91e-0417550361fdafba120fbda063d4dc05263d6f8d1dcab1e1
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5B ALCAM ITGB2

9.91e-041755038de8031fdf2af187642833feb80caa64932897cf
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_memory-B_memory-6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDLIM1 ACP5 DNAH8

9.91e-04175503eaec7fda07a9537d067ca13b607a8ab201caa7c4
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLC10A1 MTHFD1 ALCAM

1.01e-03176503f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCellMild/Remission-B_memory-6|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ACP5 ITGB2 DNAH8

1.02e-031775038f2ce5ffc94ca90412cb6899629f322dc778215c
ToppCellSevere-B_memory-6|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PDLIM1 ACP5 DNAH8

1.02e-03177503c4c3511782d5febd0c8b369eebe9355ad3c3bcf2
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5B ALCAM FHIP1A

1.02e-031775039af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAM114A1 EYS MYO5B

1.04e-031785036ad46b0720298bcb927fd53468bb4ea0c199ad35
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDLIM1 GUCY2C ACP5

1.04e-03178503be1d991c5a0a5be22f14f57d34ee1330f1a12963
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP11 BSN FAM135A

1.04e-03178503fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5B MTHFD1 ALCAM

1.04e-03178503a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5B MTHFD1 ALCAM

1.04e-03178503b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FRY ALCAM DNAI3

1.06e-0317950314fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellCOVID-19_Moderate-B_intermediate|World / disease group, cell group and cell class

PDLIM1 ACP5 DNAH8

1.07e-03180503bd81b87a6dc81e5ab4a6c948eb0c80f14401a6a7
ToppCellcontrol-Lymphoid-B_cell|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ACP5 ITGB2 DNAH8

1.09e-03181503e414303bb90e5fe7b667c2acf9a50f8694b90e54
DiseaseDiarrhea

MYO5B GUCY2C

1.35e-0411472C0011991
DiseaseDrug Use Disorders

PLA2R1 APPL2 DNAH8

8.25e-04115473C0013222
DiseaseDrug Dependence

PLA2R1 APPL2 DNAH8

8.25e-04115473C1510472
DiseaseDrug habituation

PLA2R1 APPL2 DNAH8

8.25e-04115473C0013170
DiseaseSubstance Dependence

PLA2R1 APPL2 DNAH8

8.25e-04115473C0038580
DiseaseSubstance Use Disorders

PLA2R1 APPL2 DNAH8

8.25e-04115473C0038586
DiseaseSubstance-Related Disorders

PLA2R1 APPL2 DNAH8

8.25e-04115473C0236969
DiseaseDrug abuse

PLA2R1 APPL2 DNAH8

8.25e-04115473C0013146
DiseaseOrganic Mental Disorders, Substance-Induced

PLA2R1 APPL2 DNAH8

8.25e-04115473C0029231
DiseasePrescription Drug Abuse

PLA2R1 APPL2 DNAH8

8.25e-04115473C4316881
DiseaseSubstance abuse problem

PLA2R1 APPL2 DNAH8

8.46e-04116473C0740858
Diseasestimulant use measurement

EYS FAM135A

9.14e-0428472EFO_0600076
Diseaseoral microbiome measurement

APPL2 NRDC

2.05e-0342472EFO_0801229
Diseasealcohol dependence measurement

FAM114A1 KLB

3.49e-0355472EFO_0007835

Protein segments in the cluster

PeptideGeneStartEntry
KFSKMKTAYEEVTTE

ANKRD18A

876

Q8IVF6
SVLTTKKTYSDDKEM

VCAN

2156

P13611
FSKMKTAYEDVTTEL

ANKRD18B

886

A2A2Z9
VTKMVDERTDYLTKS

AKAP11

896

Q9UKA4
EESVTESTKQITYMI

DNAI3

171

Q8IWG1
TESYKETLHKTMVTR

RBM10

911

P98175
DSTMVLLYTSVDTKK

GUCY2C

376

P25092
KTSVEEMIASTAYLE

FHIP1B

341

Q8N612
TTMEKEKVSSVFYIT

OR8D2

266

Q9GZM6
VDSTKDSYVLVSKMD

MAGEB3

171

O15480
TDYMTSLKKEVKTSS

EYS

1821

Q5T1H1
MVKFIKETYLDTVTE

KIAA0825

271

Q8IV33
YITKVMSKSSAEVIA

DPYSL2

251

Q16555
YVMIDDISELTKDST

BSN

3231

Q9UPA5
IKYSKLLSMEVSDTS

MFSD6L

551

Q8IWD5
SSKMDKYETEESSVA

FAM135A

436

Q9P2D6
KITEMITVVQTYSTL

DNAH8

371

Q96JB1
KTKMIYTAATTEETI

SLC10A1

316

Q14973
AVTSRMVKTYEKLTE

ITGB2

321

P05107
KVTVEEVMTTTAYLD

FHIP1A

326

Q05DH4
KISVYTGKSETITDM

ADGRF2

171

Q8IZF7
SMAVKTDSTTEVIYE

APPL2

501

Q8NEU8
TDSRVKTEDTTAIYM

KLB

421

Q86Z14
TYLSKTLTEEEAKMI

FRY

536

Q5TBA9
MEELKILSDTYTVEK

HAUS4

281

Q9H6D7
MTSTLEYKTTKADIQ

ALCAM

201

Q13740
TTESEVMKYITSLNE

MTHFD1

76

P11586
KTKTIEEVYMSSIES

FAM114A1

436

Q8IWE2
SSLVIDKESEVYKML

PDLIM1

186

O00151
SLKDAVITVMYTAVT

OR1A1

266

Q9P1Q5
LTTVKEKASAVMYTA

OR1M1

266

Q8NGA1
ETLKNMVKSTVSYIS

UTP20

271

O75691
KDYSVTVSSLDEMVV

TMEM132B

721

Q14DG7
TIMEKSETELKDTYA

PSMD2

541

Q13200
ITSLISSVVKMKDSY

PLA2R1

561

Q13018
YLETKKVTASMEEVL

SPATA1

346

Q5VX52
IDVKRSYVTMTATKI

CHORDC1

286

Q9UHD1
SIYESVSETITKMLK

CLUL1

261

Q15846
YIMISKDTTAKEVVI

RAPGEF2

621

Q9Y4G8
SSETTKFYMTEIIIQ

UBE3D

221

Q7Z6J8
TSTESMDFLKYVVDK

NRDC

866

O43847
EISSKEMTVTYIEAS

ACP5

296

P13686
MVGSEVYSTEIKKTE

RUVBL1

96

Q9Y265
MTESFKIKTAYEESL

MYH16

641

Q9H6N6
GKVSVEYTEKMVSIS

EMG1

206

Q92979
TVRDYIQSTMETEKT

TP53RK

121

Q96S44
YSKAKMESSSVSVVS

ZMYM1

311

Q5SVZ6
KDSVYKRSMTEGSTV

TEX15

1471

Q9BXT5
TTVLATKTAEYSEMV

VPS13D

1326

Q5THJ4
TTSTYTMEVERLKKE

MYO5B

951

Q9ULV0
EVFTETTYESTKMIE

MYBPC2

691

Q14324