Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontubulin-tyrosine ligase activity

TTLL12 TTL

7.73e-062562GO:0004835
GeneOntologyBiologicalProcessnucleoside bisphosphate metabolic process

CES1 ACSF3 HMGCS2 SULT1C4 PAPSS2

4.15e-05142565GO:0033865
GeneOntologyBiologicalProcessribonucleoside bisphosphate metabolic process

CES1 ACSF3 HMGCS2 SULT1C4 PAPSS2

4.15e-05142565GO:0033875
GeneOntologyBiologicalProcesspurine nucleoside bisphosphate metabolic process

CES1 ACSF3 HMGCS2 SULT1C4 PAPSS2

4.15e-05142565GO:0034032
GeneOntologyBiologicalProcesspositive regulation of mRNA cis splicing, via spliceosome

EXOSC10 UPF3B

7.20e-055562GO:1905746
GeneOntologyBiologicalProcessregulation of mRNA cis splicing, via spliceosome

EXOSC10 UPF3B

7.20e-055562GO:1905744
DomainTF_fork_head_CS_2

FOXB2 FOXL1 FOXP3

3.54e-0446563IPR030456
DomainTF_fork_head_CS_1

FOXB2 FOXL1 FOXP3

3.77e-0447563IPR018122
DomainFH

FOXB2 FOXL1 FOXP3

4.27e-0449563SM00339
DomainFORK_HEAD_1

FOXB2 FOXL1 FOXP3

4.27e-0449563PS00657
DomainFORK_HEAD_2

FOXB2 FOXL1 FOXP3

4.27e-0449563PS00658
DomainFork_head_dom

FOXB2 FOXL1 FOXP3

4.27e-0449563IPR001766
DomainFORK_HEAD_3

FOXB2 FOXL1 FOXP3

4.27e-0449563PS50039
DomainForkhead

FOXB2 FOXL1 FOXP3

4.27e-0449563PF00250
Domain-

CUL3 FOXB2 PREX2 FOXL1 FOXP3

4.87e-042185651.10.10.10
DomainEF_hand_dom

PLCZ1 LPCAT1 SPARC DNAH7 RYR3

6.46e-04232565IPR002048
DomainTTL

TTLL12 TTL

6.74e-0413562PS51221
DomainTTL/TTLL_fam

TTLL12 TTL

6.74e-0413562IPR004344
DomainTTL

TTLL12 TTL

6.74e-0413562PF03133
DomainWHTH_DNA-bd_dom

CUL3 FOXB2 PREX2 FOXL1 FOXP3

7.81e-04242565IPR011991
DomainDynein_heavy_chain_D4_dom

DNAH12 DNAH7

7.85e-0414562IPR024317
DomainDynein_heavy_dom-2

DNAH12 DNAH7

7.85e-0414562IPR013602
DomainDHC_N2

DNAH12 DNAH7

7.85e-0414562PF08393
DomainAAA_8

DNAH12 DNAH7

7.85e-0414562PF12780
DomainDHC_fam

DNAH12 DNAH7

9.04e-0415562IPR026983
DomainDynein_heavy_dom

DNAH12 DNAH7

9.04e-0415562IPR004273
DomainDynein_heavy

DNAH12 DNAH7

9.04e-0415562PF03028
DomainEF_HAND_2

PLCZ1 LPCAT1 SPARC RYR3

5.06e-03231564PS50222
Domain-

GTPBP4 DNAH12 ABCC11 MSH3 SULT1C4 PAPSS2 DNAH7

6.67e-037465673.40.50.300
DomainTHIOREDOXIN_2

ERP27 DNAJC16

7.37e-0343562PS51352
Domain-

PLCZ1 LPCAT1 SPARC RYR3

7.75e-032615641.10.238.10
Pubmed

Structure of the BTB domain of Keap1 and its interaction with the triterpenoid antagonist CDDO.

CUL3 KEAP1

2.64e-06257224896564
Pubmed

Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes.

CUL3 KEAP1

2.64e-06257230273379
Pubmed

Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction.

NOTCH1 FOXP3

2.64e-06257223161436
Pubmed

Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease.

NOS3 NOTCH1

2.64e-06257223583836
Pubmed

Notch signaling regulates tumor-induced angiogenesis in SPARC-overexpressed neuroblastoma.

SPARC NOTCH1

2.64e-06257222956186
Pubmed

Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3.

CUL3 KEAP1

2.64e-06257218251510
Pubmed

Immune tolerance against infused FVIII in hemophilia A is mediated by PD-L1+ Tregs.

F8 FOXP3

2.64e-06257236107620
Pubmed

De novo variants in CUL3 are associated with global developmental delays with or without infantile spasms.

CUL3 KEAP1

2.64e-06257232341456
Pubmed

A Multi-Omics Approach Using a Mouse Model of Cardiac Malformations for Prioritization of Human Congenital Heart Disease Contributing Genes.

NOS3 NOTCH1

2.64e-06257234504875
Pubmed

[Significance of CD4+ CD25+ CD127(low) regulatory T cells and notch1 pathway in the pathogenesis of aplastic anemia].

NOTCH1 FOXP3

2.64e-06257218844067
Pubmed

CD4+FOXP3+ regulatory T cells confer long-term regulation of factor VIII-specific immune responses in plasmid-mediated gene therapy-treated hemophilia mice.

F8 FOXP3

2.64e-06257219713458
Pubmed

Pterisolic Acid B is a Nrf2 Activator by Targeting C171 within Keap1-BTB Domain.

CUL3 KEAP1

2.64e-06257226757824
Pubmed

Effect of B-cell depletion using anti-CD20 therapy on inhibitory antibody formation to human FVIII in hemophilia A mice.

F8 FOXP3

2.64e-06257221160036
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

CUL3 GTPBP4 EXOSC10 G3BP2 KEAP1 XAB2

3.55e-0625157628077445
Pubmed

Distinct expression patterns of ICK/MAK/MOK protein kinases in the intestine implicate functional diversity.

MAK CILK1

7.91e-06357224244486
Pubmed

Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism.

CUL3 KEAP1

7.91e-06357221357422
Pubmed

Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1.

CUL3 KEAP1

7.91e-06357219489739
Pubmed

Mechanism of cullin3 E3 ubiquitin ligase dimerization.

CUL3 KEAP1

7.91e-06357222911784
Pubmed

Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly.

CUL3 KEAP1

7.91e-06357237156295
Pubmed

Heteroaromatic 4-arylquinols are novel inducers of nuclear factor-erythroid 2-related factor 2 (Nrf2).

CUL3 KEAP1

7.91e-06357220599909
Pubmed

Development of a High-Throughput Cul3-Keap1 Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay for Identifying Nrf2 Activators.

CUL3 KEAP1

7.91e-06357230383469
Pubmed

Zinc-binding triggers a conformational-switch in the cullin-3 substrate adaptor protein KEAP1 that controls transcription factor NRF2.

CUL3 KEAP1

7.91e-06357230261176
Pubmed

Covalent modification of Keap1 at Cys77 and Cys434 by pubescenoside a suppresses oxidative stress-induced NLRP3 inflammasome activation in myocardial ischemia-reperfusion injury.

CUL3 KEAP1

7.91e-06357233391509
Pubmed

FOXP3 expression is modulated by TGF‑β1/NOTCH1 pathway in human melanoma.

NOTCH1 FOXP3

7.91e-06357229620159
Pubmed

Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells.

NOTCH1 FOXP3

7.91e-06357218550850
Pubmed

Gene-expression signature regulated by the KEAP1-NRF2-CUL3 axis is associated with a poor prognosis in head and neck squamous cell cancer.

CUL3 KEAP1

7.91e-06357229306329
Pubmed

Integrated analysis of patients with KEAP1/NFE2L2/CUL3 mutations in lung adenocarcinomas.

CUL3 KEAP1

7.91e-06357234617407
Pubmed

Induction of activation of the antioxidant response element and stabilization of Nrf2 by 3-(3-pyridylmethylidene)-2-indolinone (PMID) confers protection against oxidative stress-induced cell death.

CUL3 KEAP1

7.91e-06357222245129
Pubmed

Carnosic acid prevents dextran sulfate sodium-induced acute colitis associated with the regulation of the Keap1/Nrf2 pathway.

CUL3 KEAP1

7.91e-06357228887507
Pubmed

The lysophosphatidylserine receptor GPR174 constrains regulatory T cell development and function.

GPR174 FOXP3

7.91e-06357226077720
Pubmed

Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction.

CUL3 KEAP1

7.91e-06357218417180
Pubmed

Impact of KEAP1/NFE2L2/CUL3 mutations on duration of response to EGFR tyrosine kinase inhibitors in EGFR mutated non-small cell lung cancer.

CUL3 KEAP1

7.91e-06357231319993
Pubmed

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy.

CUL3 KEAP1

7.91e-06357218757741
Pubmed

Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex.

CUL3 KEAP1

7.91e-06357216790436
Pubmed

Britanin Ameliorates Cerebral Ischemia-Reperfusion Injury by Inducing the Nrf2 Protective Pathway.

CUL3 KEAP1

7.91e-06357228186440
Pubmed

CAND1 exchange factor promotes Keap1 integration into cullin 3-RING ubiquitin ligase during adipogenesis.

CUL3 KEAP1

7.91e-06357226219975
Pubmed

CCRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner.

MAK CILK1

7.91e-06357223743448
Pubmed

The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.

CUL3 KEAP1

7.91e-06357215367669
Pubmed

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.

CUL3 KEAP1

7.91e-06357215282312
Pubmed

Identification of de novo mutations and rare variants in hypoplastic left heart syndrome.

NOTCH1 FOXL1

7.91e-06357221457232
Pubmed

Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells.

CUL3 KEAP1

7.91e-06357223454126
Pubmed

An integrative investigation on significant mutations and their down-stream pathways in lung squamous cell carcinoma reveals CUL3/KEAP1/NRF2 relevant subtypes.

CUL3 KEAP1

7.91e-06357232434476
Pubmed

Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells.

NOTCH1 FOXP3

7.91e-06357227267497
Pubmed

Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.

CUL3 KEAP1

7.91e-06357232854194
Pubmed

A small-molecule inducer of the antioxidant response element.

CUL3 KEAP1

7.91e-06357220534351
Pubmed

Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells.

CUL3 KEAP1

7.91e-06357227697860
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

CUL3 GTPBP4 MCMBP PELO SYNM G3BP2 PSMD8 XAB2

1.09e-0565357833742100
Pubmed

Notch signaling regulates the FOXP3 promoter through RBP-J- and Hes1-dependent mechanisms.

NOTCH1 FOXP3

1.58e-05457218777163
Pubmed

Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice.

KEAP1 FOXP3

1.58e-05457228507037
Pubmed

A comparative analysis indicates SLC7A11 expression regulate the prognostic value of KEAP1-NFE2L2-CUL3 mutations in human uterine corpus endometrial carcinoma.

CUL3 KEAP1

1.58e-05457238876457
Pubmed

Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells.

CUL3 KEAP1

1.58e-05457225628777
Pubmed

The lysine deacetylase Sirtuin 1 modulates the localization and function of the Notch1 receptor in regulatory T cells.

NOTCH1 FOXP3

1.58e-05457228377411
Pubmed

ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation.

CUL3 FOXP3

1.58e-05457234491895
Pubmed

Unique pattern of component gene disruption in the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in serous ovarian cancer.

CUL3 KEAP1

1.58e-05457225114896
Pubmed

Chromosomal localization of zinc finger protein genes in man and mouse.

SPARC CES1

1.58e-0545722565878
Pubmed

SPARC, FOXP3, CD8 and CD45 correlation with disease recurrence and long-term disease-free survival in colorectal cancer.

SPARC FOXP3

1.58e-05457221818290
Pubmed

A mutation of Keap1 found in breast cancer impairs its ability to repress Nrf2 activity.

CUL3 KEAP1

1.58e-05457217822677
Pubmed

Regulation of notch1 signaling by nrf2: implications for tissue regeneration.

KEAP1 NOTCH1

1.58e-05457220628156
Pubmed

DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting KEAP1-Mediated NRF2 Ubiquitination.

CUL3 KEAP1

1.58e-05457236965071
Pubmed

Blockade of individual Notch ligands and receptors controls graft-versus-host disease.

NOTCH1 FOXP3

1.58e-05457223454750
Pubmed

Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.

CUL3 KEAP1

1.58e-05457225742418
Pubmed

Mechanism of chemical activation of Nrf2.

CUL3 KEAP1

1.58e-05457222558124
Pubmed

Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes.

CUL3 KEAP1

1.58e-05457220027226
Pubmed

USP15 negatively regulates Nrf2 through deubiquitination of Keap1.

CUL3 KEAP1

1.58e-05457223727018
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DNAJC16 CILK1 DNAH7 THOC5

2.44e-0510257410231032
Pubmed

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.

CUL3 KEAP1

2.63e-05557215601839
Pubmed

p97 Negatively Regulates NRF2 by Extracting Ubiquitylated NRF2 from the KEAP1-CUL3 E3 Complex.

CUL3 KEAP1

2.63e-05557228115426
Pubmed

A novel yeast model detects Nrf2 and Keap1 interactions with Hsp90.

CUL3 KEAP1

2.63e-05557235088844
Pubmed

Keap1 controls protein S-nitrosation and apoptosis-senescence switch in endothelial cells.

KEAP1 NOS3

2.63e-05557231491600
Pubmed

PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex.

CUL3 KEAP1

2.63e-05557217046835
Pubmed

RBM45 Modulates the Antioxidant Response in Amyotrophic Lateral Sclerosis through Interactions with KEAP1.

CUL3 KEAP1

2.63e-05557225939382
Pubmed

Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells.

NOTCH1 FOXP3

2.63e-05557222503540
Pubmed

Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract.

NOS3 NOTCH1

2.63e-05557227107132
Pubmed

Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells--evidence for cullin dimerization.

CUL3 KEAP1

2.63e-05557217254749
Pubmed

KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta.

CUL3 KEAP1

2.63e-05557219818716
Pubmed

Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.

CUL3 KEAP1

2.63e-05557216785233
Pubmed

Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice.

KEAP1 NOTCH1

2.63e-05557229515034
Pubmed

CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.

CUL3 KEAP1

2.63e-05557216449638
Pubmed

Association of Notch pathway down-regulation with Triple Negative/Basal-like breast carcinomas and high tumor-infiltrating FOXP3+ Tregs.

NOTCH1 FOXP3

2.63e-05557227118257
Pubmed

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.

G3BP2 UPF3B THOC5 XAB2

3.78e-0511457431553912
Pubmed

Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation.

EXOSC10 UPF3B

3.94e-05657216789828
Pubmed

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.

CUL3 KEAP1

3.94e-05657215572695
Pubmed

c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host-microbiota homeostasis.

NOTCH1 FOXP3

5.51e-05757230778241
Pubmed

A genome-wide association study of carotid atherosclerosis in HIV-infected men.

THOC5 RYR3

5.51e-05757220009918
Pubmed

Opposing effects of Nrf2 and Nrf2-activating compounds on the NLRP3 inflammasome independent of Nrf2-mediated gene expression.

CUL3 KEAP1

5.51e-05757228247911
Pubmed

A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62.

CUL3 KEAP1

5.51e-05757220421418
Pubmed

Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein.

CUL3 KEAP1

5.51e-05757222215675
Pubmed

The COP9 signalosome, cullin 3 and Keap1 supercomplex regulates CHOP stability and adipogenesis.

CUL3 KEAP1

5.51e-05757223213463
Pubmed

Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis.

CUL3 KEAP1

7.34e-05857230765703
Pubmed

Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway.

CUL3 KEAP1

7.34e-05857215983046
Pubmed

Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase.

MAK CILK1

7.34e-05857216954377
Pubmed

A mechanism for the suppression of homologous recombination in G1 cells.

CUL3 KEAP1

9.43e-05957226649820
Pubmed

Location of preganglionic neurons is independent of birthdate but is correlated to reelin-producing cells in the spinal cord.

VSX2 NOS3

9.43e-05957215236237
Pubmed

Hypoxia-responsive microRNA-101 promotes angiogenesis via heme oxygenase-1/vascular endothelial growth factor axis by targeting cullin 3.

CUL3 KEAP1

9.43e-05957224844779
Pubmed

Kelch-like Protein 21 (KLHL21) Targets IκB Kinase-β to Regulate Nuclear Factor κ-Light Chain Enhancer of Activated B Cells (NF-κB) Signaling Negatively.

CUL3 KEAP1

9.43e-05957227387502
Pubmed

Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination.

CUL3 KEAP1

9.43e-05957224322982
Pubmed

Substrate-mediated regulation of cullin neddylation.

CUL3 KEAP1

9.43e-05957217439941
Pubmed

Keap1-MCM3 interaction is a potential coordinator of molecular machineries of antioxidant response and genomic DNA replication in metazoa.

MCMBP KEAP1

9.43e-05957230108253
Pubmed

Hippo signaling is required for Notch-dependent smooth muscle differentiation of neural crest.

NOS3 NOTCH1

1.18e-041057226253400
Pubmed

A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool.

VSX2 NOTCH1

1.18e-041057217728344
CytobandEnsembl 112 genes in cytogenetic band chr12p12

PLCZ1 ERP27 GYS2

3.86e-04113573chr12p12
Cytoband12p12.3

PLCZ1 ERP27

7.33e-043257212p12.3
Cytoband14q24.3

AREL1 VSX2

6.03e-039357214q24.3
CytobandEnsembl 112 genes in cytogenetic band chr16q12

CES1 ABCC11

7.34e-03103572chr16q12
GeneFamilyForkhead boxes

FOXB2 FOXL1 FOXP3

1.25e-0443413508
GeneFamilyTubulin tyrosine ligase family

TTLL12 TTL

4.49e-0414412779
GeneFamilyDyneins, axonemal

DNAH12 DNAH7

6.68e-0417412536
GeneFamilyEF-hand domain containing

PLCZ1 LPCAT1 DNAH7 RYR3

1.49e-03219414863
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

SYNM CMYA5

1.96e-0329412396
ToppCellAdult-Endothelial-endothelial_cell_of_artery|Adult / Lineage, Cell type, age group and donor

SULT1C4 F8 NOS3 PREX2 RYR3

4.02e-061865752d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 NOS3 PREX2 NOTCH1

4.70e-06192575d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 NOS3 PREX2 NOTCH1

4.70e-061925752bfac6b3956265205ca47d06888851ed68b65999
ToppCellfacs-BAT-Fat-3m-Endothelial-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC PAPSS2 NOS3 PREX2 NOTCH1

4.82e-06193575e340064cd146deac03f2d0fd43e2e218bb6057c9
ToppCellfacs-BAT-Fat-3m-Endothelial-endothelial_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC PAPSS2 NOS3 PREX2 NOTCH1

4.82e-06193575a211b386fd0fb9da9937361d29d90925a72c9715
ToppCellfacs-BAT-Fat-3m-Endothelial|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC PAPSS2 NOS3 PREX2 NOTCH1

4.82e-061935753086c33f4d6fab66966818737f95ae4d6b2615b0
ToppCellASK452-Endothelial-Endothelium|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

SPARC SULT1C4 PAPSS2 NOS3 PREX2

5.46e-06198575e282769f5fa1765bcce79a0ed9d761bf2e14b012
ToppCellBac-SEP-Lymphocyte-T_NK-Treg|Bac-SEP / Disease, Lineage and Cell Type

GTPBP4 SYNM NOS3 FOXP3

4.19e-051515745df5e754a45b8a592ca7ad49a70953be1615066a
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAK DNAH12 KIAA0825 DNAH7

6.50e-05169574fba841664939c771881ba97f14ef1df6635c04ff
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP3 SYNM CES1 FOXL1

7.11e-051735743001dd39244ef0a5a475d569a78f4ae427a55db6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP3 SYNM CES1 FOXL1

7.11e-05173574c88883fb2a33e21d4201aa393674aa3f2ad780c9
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC SYNM F8 PREX2

8.66e-05182574f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCellPericytes-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CLIP3 SPARC SYNM FOXL1

8.84e-051835744617b18da8d699a44e4c47980197b1e7eb951470
ToppCellEndothelial-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

SPARC SULT1C4 F8 PREX2

8.84e-051835742c3f2c25c38f0598b4787d2ec335efe00fdc9751
ToppCellILEUM-inflamed-(7)_Lymphatics|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SYNM CMYA5 SULT1C4 F8

9.22e-05185574d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC SYNM F8 NOS3

9.41e-0518657490d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC SYNM F8 NOS3

9.41e-051865742cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT1 DNAH12 CES1 GALNTL5

9.61e-051875748c69fd469df2915c56ede534cee3ef23d5f64ebf
ToppCelldroplet-Kidney-nan-3m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 NOS3 PREX2

9.61e-05187574d72012e94857606f39975cf672f6b8c2e0fe093e
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

PAPSS2 F8 NOS3 PREX2

9.61e-0518757481affaab3fe3e1daea45ada6445e906ddd33950e
ToppCelldroplet-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 NOS3 PREX2

9.81e-05188574ca3be1942b179b512ab242acded31f1e3748c753
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLIP3 SPARC HMGCS2 FOXL1

1.00e-04189574378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC SYNM F8 NOS3

1.00e-04189574ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLIP3 SPARC HMGCS2 FOXL1

1.00e-04189574f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SYNM F8 NOS3 NOTCH1

1.00e-0418957455a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 NOS3 NOTCH1

1.00e-0418957492319bef1f00d6048ba8f9f8b5c6dbb896686b74
ToppCellEndothelial-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SPARC SULT1C4 F8 PREX2

1.04e-04191574f702dfe88a9b04091dae87df61b2b4f43525f86a
ToppCelldroplet-Kidney-nan-3m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 NOS3 PREX2

1.04e-04191574dc58d45fafd224d2761aefbe0ce79f66b50c1c03
ToppCellfacs-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC NOS3 PREX2 NOTCH1

1.06e-04192574777e386a17bba9ec450bb9d64d8a9ab98d9a63ff
ToppCellfacs-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC NOS3 PREX2 NOTCH1

1.06e-0419257460a2409546525a40a5658e0f9d6a50c37f28bb96
ToppCellfacs-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC NOS3 PREX2 NOTCH1

1.06e-041925740f9db6091b373334b9beabe0e5782bf2bc54690b
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SYNM CMYA5 SULT1C4 F8

1.06e-04192574d43caf42ec744e895137f31ef65a990e250669d2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC F8 PREX2 RYR3

1.06e-04192574c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 PREX2 NOTCH1

1.09e-04193574826b8dd801298b3e0cd76232feae5a14026b8806
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 PREX2 NOTCH1

1.09e-041935748084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

C12orf56 NOS3 PREX2 RYR3

1.09e-041935740b328f725f6feba263783eaca60c142e80df90f3
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 PREX2 NOTCH1

1.09e-0419357487d3a577d37fb0cb4b6313c596310de452bc3872
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC F8 PREX2 RYR3

1.09e-0419357452e918884877b6659cdca0496390e440f73694a9
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 PREX2 NOTCH1

1.09e-04193574d485634c564b268e344b6a2863c26f6adaec9e38
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 PREX2 NOTCH1

1.11e-04194574c8b9551b93a5aed62154b487db90130604a6125c
ToppCellfacs-Kidney-nan-3m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 PREX2 NOTCH1

1.11e-041945745fa2dfca32cca4abfda0af90b83f2b2a826f9b6e
ToppCellfacs-Kidney-nan-3m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 PREX2 NOTCH1

1.11e-0419457404df35246287815bdd28adaf885bdb98cf49524e
ToppCellfacs-Kidney-nan-3m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 PREX2 NOTCH1

1.11e-0419457490928d6c96c6304ae35dcc0275f7889de93da100
ToppCell(6)_Endothelial-D|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SPARC F8 NOS3 PREX2

1.13e-04195574c0005a5f2dc63a0cc254c45ac89a2f42df6f8bde
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 PREX2 NOTCH1

1.13e-0419557412ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 NOS3 PREX2

1.13e-0419557485df110f753f58ab017018c54ee454edb4428e29
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPARC SULT1C4 NOS3 PREX2

1.15e-04196574c5fe470f11ee4962bcfb30cddfd8c078af5b1222
ToppCellASK428-Endothelial-Endothelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SPARC SULT1C4 F8 PREX2

1.15e-04196574b1a81eddb91fb462360692b7b0a3ba4a947eac40
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC F8 NOS3 PREX2

1.15e-041965747cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC F8 PREX2 NOTCH1

1.15e-0419657465d882c6e7f6d5778b8a5fd4fdaf012e1b9f6100
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 PREX2 NOTCH1

1.17e-04197574deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC NOS3 PREX2 RYR3

1.17e-04197574cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH12 KIAA0825 GYS2 DNAH7

1.17e-041975746e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 PREX2 NOTCH1

1.17e-04197574a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPARC SULT1C4 PAPSS2 PREX2

1.17e-041975749e948b2e0f7e426f1e6f95bbbf4282fbddc2b99d
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPARC PELO SULT1C4 PREX2

1.20e-041985740a4626b51ba8b52acbaf616f0ced850079cd7149
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SULT1C4 PAPSS2 F8 PREX2

1.20e-04198574b11d21aa96a0c91e958ae7ed8fd56546aeaebb91
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

SYNM F8 NOS3 PREX2

1.20e-0419857456b746e5791b47fe33a7872f0942ae0747b13d4a
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

SPARC F8 NOS3 PREX2

1.20e-041985748689090bce9ab6e8f122426a404037e572c6713b
ToppCellEndothelial-A|World / lung cells shred on cell class, cell subclass, sample id

SPARC F8 NOS3 PREX2

1.20e-04198574dd096d4b9f428615f927f7df7cbf5cede0e0e605
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPARC F8 NOS3 PREX2

1.20e-041985745784e0f9988c917026a692a61b09c7e77e540d13
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC F8 NOS3 PREX2

1.20e-04198574451003a21162eeae90739fdb502bb50b362d80c8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC F8 NOS3 PREX2

1.20e-04198574440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPARC SULT1C4 PAPSS2 F8

1.20e-041985742400f8b8c51739ea2ae2b9f24f44eaeefa2bb6fc
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SULT1C4 PAPSS2 F8 PREX2

1.20e-0419857455378e15360f867c9500b03293814965562ae55d
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SULT1C4 PAPSS2 F8 PREX2

1.20e-04198574605ef5b61750226b93bca48166d8a1f6450e80e0
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC F8 PREX2 NOTCH1

1.20e-04198574f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

VSX2 F8 NOS3 PREX2

1.22e-041995749735a1dc10910f02f1106b20ae5ab4c09c21305e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC F8 NOS3 PREX2

1.22e-041995748b62d43af8b2ebb4c1b2d068d50beaf35728dbe7
ToppCellASK452-Endothelial|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

SPARC PAPSS2 NOS3 PREX2

1.22e-041995740bc97a9a78aaafd1554ae6a61356ed9ea4983fa5
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPARC F8 NOS3 PREX2

1.22e-041995746a7ecc3a68b9cfc49e50abaeb16e2eee3795377e
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-Treg|Bac-SEP / Disease, condition lineage and cell class

GTPBP4 SYNM NOS3 FOXP3

1.22e-04199574e0b6136e28b813299b7ffbe37f1cf830e60cd7d8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC F8 NOS3 PREX2

1.24e-042005742e47888e041ec3d265425d1df97b6665c6da889c
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Artery-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SULT1C4 PAPSS2 F8 NOS3

1.24e-04200574622206c33640cb2694fe158e8dc55515bb7bd4f5
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Artery|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SULT1C4 PAPSS2 F8 NOS3

1.24e-04200574590d1c0f86f136c7e76ea107fbb8ac5ff1164386
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Artery|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SULT1C4 PAPSS2 F8 NOS3

1.24e-042005745b4a54cd81bc4d9f5e92798362239e1aa1b70bee
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC F8 NOS3 PREX2

1.24e-0420057450fa0f8a3e490d5941b34e66a10158eba6c909d4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial|GW10 / Sample Type, Dataset, Time_group, and Cell type.

SPARC DNAH12 NOS3 NOTCH1

1.24e-04200574ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC F8 NOS3 PREX2

1.24e-04200574b1be27d134a8633e3e7862c6a0d7be2001d387f0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte|GW10 / Sample Type, Dataset, Time_group, and Cell type.

SPARC DNAH12 NOS3 NOTCH1

1.24e-0420057498a994692440cb4f505b050276f0c8022c814a21
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADAM2 DNAH7 PREX2 RYR3

1.24e-0420057407d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC F8 NOS3 PREX2

1.24e-042005747a69ad5b6c84f1aebacea5cacb9bc5c63dfd1dac
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SPARC PAPSS2 F8 PREX2

1.24e-0420057430dc7ffef2052ee8610cdca952ca12f240bcec50
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_venous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPARC F8 NOS3 PREX2

1.24e-04200574a3b09580738783c6bff31ea33d5188912e56b8a7
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPARC F8 NOS3 PREX2

1.24e-04200574310c75e13be9194312a8b686804edcf13d44caf5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPARC F8 NOS3 PREX2

1.24e-04200574dba96cda5f3b780a3d4171b61bc8aaddc1f5d466
ToppCellBiopsy_Control_(H.)-Endothelial-Endothelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

SPARC SULT1C4 F8 PREX2

1.24e-042005740242d465da2dfba0da629a43e152949c5192465b
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat-Inhibitory_Neuron.Gad1Gad2-Chat-Slc17a8.Chat_(cholinergic_interneuron)|Striatum / BrainAtlas - Mouse McCarroll V32

PLCZ1 GPR174 GYS2

1.27e-04765733073a8ace46ad18bddd22ec8f3a1b59ee2fd989d
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat-Inhibitory_Neuron.Gad1Gad2-Chat-Slc17a8.Chat_(cholinergic_interneuron)-|Striatum / BrainAtlas - Mouse McCarroll V32

PLCZ1 GPR174 GYS2

1.27e-04765733f5865b9cb6648b88eb873018e513c5efb457ae5
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat|Striatum / BrainAtlas - Mouse McCarroll V32

PLCZ1 GPR174 GYS2

1.27e-0476573041a8984b3ae4bb03ae6db8234c1333ac73098fa
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

PLCZ1 GPR174 GYS2

1.71e-04845739417fffe0ba79f5851920258dcd0f6c09218be13
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Gfap_(Gfap)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

C12orf56 PAPSS2 ITIH4

3.30e-04105573c41264e8b7d306d5d3ffa5b29eb36c7131d1cedf
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Gfap_(Gfap)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

C12orf56 PAPSS2 ITIH4

3.30e-04105573ed570cfdd452767dfb4dcae72282fe0fb25a4029
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Gfap_(Gfap)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

C12orf56 PAPSS2 ITIH4

3.30e-04105573ed3a431195c42c96c7d9c420e4b9fb00f415012d
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAK KEAP1 CDH9

4.09e-0411357334ae3dec5ec7585d155ea61de6adc42aa4f45226
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAK KEAP1 CDH9

4.09e-0411357379ba2eb8f85e5da4c19c838df881c18ffdc450fb
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAK KEAP1 CDH9

4.09e-0411357391d55fe6fb1c1472867d74461f5b9e4f17db01cd
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM2 HMGCS2 PAPSS2

6.29e-04131573d706405453408fbcfcabb1c7702b80f9e649ffca
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAH12 GPR174 RYR3

7.17e-041375730c82f815c014d01213d23b466043d6e57186dceb
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-MAIT|GI_small-bowel / Manually curated celltypes from each tissue

MAK GYS2 ITIH4

8.61e-041465731cb2e157222631e8915d89b255a843d16d7d99cc
Diseasediabetic angiopathy (biomarker_via_orthology)

SPARC NOS3

2.12e-054562DOID:11713 (biomarker_via_orthology)
Diseasebronchiolitis obliterans (biomarker_via_orthology)

NOS3 FOXP3

5.28e-056562DOID:2799 (biomarker_via_orthology)
Diseaseprimary ciliary dyskinesia (is_implicated_in)

DNAH7 BRWD1

5.28e-056562DOID:9562 (is_implicated_in)
DiseaseHepatic Insufficiency

KEAP1 NOS3

1.26e-049562C1306571
DiseaseColonic Neoplasms

SPARC HMGCS2 NOTCH1 ITIH4

2.02e-04152564C0009375
Diseaseendometrial carcinoma (is_implicated_in)

SPARC MSH3

2.31e-0412562DOID:2871 (is_implicated_in)
DiseaseOligospermia

NOS3 BRWD1

2.31e-0412562C0028960
DiseaseMalignant tumor of colon

SPARC HMGCS2 NOTCH1 ITIH4

2.40e-04159564C0007102
Diseasehepatocellular carcinoma (is_marker_for)

CES1 HMGCS2 PREX2 ITIH4 FOXP3

2.67e-04301565DOID:684 (is_marker_for)
DiseaseHepatitis

SPARC KEAP1

3.66e-0415562C0019158
DiseasePolyposis, Adenomatous Intestinal

MSH3 ITIH4

4.17e-0416562C2713442
DiseaseFamilial Intestinal Polyposis

MSH3 ITIH4

4.17e-0416562C2713443
DiseaseDisproportionate short stature

CILK1 ANO5 PAPSS2

4.29e-0477563C0878659
DiseaseAdenomatous Polyposis Coli

MSH3 ITIH4

4.72e-0417562C0032580
DiseaseUremia

SPARC NOS3

4.72e-0417562C0041948
Diseasehepatitis B (is_marker_for)

PREX2 FOXP3

7.26e-0421562DOID:2043 (is_marker_for)
DiseaseInfiltrating duct carcinoma of female breast

MAK RPS6KA4

7.26e-0421562C3165106
Diseasesusceptibility to rheumatic fever measurement

MSH3 RYR3

1.30e-0328562EFO_0008416
Diseaseamyotrophic lateral sclerosis (is_marker_for)

KEAP1 ITIH4

1.39e-0329562DOID:332 (is_marker_for)
DiseaseCholestasis, Extrahepatic

KEAP1 NOS3

1.69e-0332562C0005398
Diseaseamino acid measurement

DNAH12 TTL HMGCS2 DNAH7 NOTCH1 RYR3

1.76e-03678566EFO_0005134
DiseaseMalignant Neoplasms

MSH3 NOS3 NOTCH1

1.87e-03128563C0006826

Protein segments in the cluster

PeptideGeneStartEntry
YYMFPRFLQHIEENI

FAM200B

481

P0CF97
NHRDAGAPTYMYEFQ

CES1

436

P23141
PESIMYFNLYREKFH

ELMOD2

261

Q8IZ81
YPPDDENKYFHNMQF

ANO5

811

Q75V66
MQKNFLPHNFRVYSY

ADAM2

61

Q99965
ENYFLIGPYFEHNMK

GYS2

61

P54840
HPFYADLMNILYDKD

GTPBP4

76

Q9BZE4
MEYYDRHFTQPHAQD

ACSF3

301

Q4G176
AEFQSPKYIFHNFME

ITIH4

531

Q14624
ERMDNIYFEYSHAFQ

MSH3

456

P20585
AMDFYDPARHNEFDF

PAPSS2

561

O95340
FHRFAEMYPAFAEEY

LPCAT1

476

Q8NF37
KFIMERFPYYREHTQ

FOXB2

41

Q5VYV0
FKRDAHGQQMIFPYY

NOTCH1

1606

P46531
YVFQHFKRYDNLMKE

KIAA0825

556

Q8IV33
FPEFLHNMDYFKFHN

FOXP3

321

Q9BZS1
RGTHMENVYDFYKPN

HMGCS2

231

P54868
IIFQDYHMKYRDNTP

ABCC11

1141

Q96J66
IPNQYDKHFMERDYT

DNAJC16

681

Q9Y2G8
LMNHLEKDQYFPFYI

DNAH12

1906

Q6ZR08
FKENYRFHAINGYIM

F8

1931

P00451
GEMFTHLYQRQYFKE

RPS6KA4

121

O75676
MYPFRFHDCKQKYDL

GPR174

121

Q9BXC1
ENNMPFFYDYHFNEN

HECTD4

981

Q9Y4D8
FFYDYHFNENKMKEL

HECTD4

986

Q9Y4D8
HQEMVNYFLSPAFRY

NOS3

461

P29474
PHMYARAYINFKNQE

UPF3B

91

Q9BZI7
QDMFAHPYQYELNHF

EXOSC10

251

Q01780
PNKFYVHNDMFRYED

G3BP2

121

Q9UN86
FMQEKDVFERYYKQH

CUL3

421

Q13618
DAMPQHFYQNEDYNE

CMYA5

2511

Q8N3K9
ILRNYMYEDFHELFQ

DNAH7

2236

Q8WXX0
RHYFNEIGQYDKDMD

GALNTL5

316

Q7Z4T8
LRMHYKYFETDDPEF

AREL1

591

O15033
YEKIPDQMFFHTDYR

BRWD1

551

Q9NSI6
ENDHLYFIFEYMKEN

MAK

71

P20794
ASPEYEENMHRYQKA

ERP27

171

Q96DN0
YQFIMDRFPFYHDNR

FOXL1

76

Q12952
YIYMHFGEVAKQEEF

KEAP1

206

Q14145
NMNALHYAAYFDVPD

CLIP3

161

Q96DZ5
INDHAPEFAMYYETF

CDH9

481

Q9ULB4
QKVDYDFSYHQMEFP

MCMBP

486

Q9BTE3
VINYAMFLEEHKYFE

XAB2

521

Q9HCS7
ENMPSEFRNKSYHYT

SYNM

331

O15061
RKVYQDMTHPLNDYF

PLCZ1

151

Q86YW0
FYKMLQHEPDRAFYG

PELO

281

Q9BRX2
FRKHEDYMQDQFTVY

SIX6OS1

86

Q8N1H7
ENDHLYFIFEYMKEN

CILK1

71

Q9UPZ9
NNYREEFRYFIHMPA

C12orf56

581

Q8IXR9
MEDYKDNPAFAFLHD

SUGP1

211

Q8IWZ8
NDMFNYVDFVDRFHE

RYR3

3971

Q15413
LARDFEKNYNMYIFP

SPARC

216

P09486
ARNPKDNMVSYYHFQ

SULT1C4

136

O75897
HQFKPEQMLYRFRYD

PREX2

451

Q70Z35
DDYEKHFTVMNYDPD

TTLL12

506

Q14166
FDYKEQLPESAYMHQ

PSMD8

176

P48556
YLFMPFDQAHKQYET

THOC5

246

Q13769
YEEGNEMFFKEFNQY

TTL

256

Q8NG68
AFNEAHYPDVYAREM

VSX2

166

P58304