Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

ABCC1 NALCN P2RX7 SCN1A SCN3A SLC49A4 SCN8A SCN9A TMEM63B KCNQ2 ATP11C ATP8B1 SLC25A26 ATP1B2 LMBRD1 ABCA10 RHCE RHD

4.91e-0912895518GO:0005215
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

NALCN SCN1A SCN3A SCN8A SCN9A

8.28e-0926555GO:0005248
GeneOntologyMolecularFunctionsuperoxide-generating NAD(P)H oxidase activity

CYBB NOX1 NOX4 NOX3

2.51e-0812554GO:0016175
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN3A SCN8A SCN9A

5.05e-0814554GO:0031402
GeneOntologyMolecularFunctionsuperoxide-generating NADPH oxidase activity

NOX1 NOX4 NOX3

7.89e-084553GO:0106292
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

CYBB NOX1 NOX4 NOX3

2.41e-0720554GO:0050664
GeneOntologyMolecularFunctionsodium channel activity

NALCN SCN1A SCN3A SCN8A SCN9A

3.10e-0752555GO:0005272
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCC1 NALCN P2RX7 SCN1A SCN3A SLC49A4 SCN8A SCN9A TMEM63B KCNQ2 SLC25A26 ATP1B2 ABCA10 RHCE RHD

4.35e-0711805515GO:0022857
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN3A SCN8A SCN9A

7.36e-0726554GO:0031420
GeneOntologyMolecularFunctionchannel activity

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A TMEM63B KCNQ2 RHCE RHD

1.46e-065255510GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A TMEM63B KCNQ2 RHCE RHD

1.49e-065265510GO:0022803
GeneOntologyMolecularFunctionmonoatomic cation channel activity

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A TMEM63B KCNQ2

4.21e-06343558GO:0005261
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ABCC1 NALCN SCN1A SCN3A SCN8A SCN9A TMEM63B KCNQ2 ATP1B2 RHCE RHD

5.70e-067585511GO:0015318
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

NALCN SCN1A SCN3A SCN8A SCN9A TMEM63B KCNQ2 ATP1B2 RHCE RHD

7.09e-066275510GO:0022890
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

NALCN SCN1A SCN3A SCN8A SCN9A ATP1B2

7.40e-06171556GO:0015081
GeneOntologyMolecularFunctionmonoatomic ion channel activity

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A TMEM63B KCNQ2

3.46e-05459558GO:0005216
GeneOntologyMolecularFunctionphosphatidylserine flippase activity

ATP11C ATP8B1

7.41e-055552GO:0140346
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A TMEM63B KCNQ2 ATP1B2

7.62e-05664559GO:0008324
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H

CYBB NOX1 NOX4 NOX3

1.36e-0495554GO:0016651
GeneOntologyMolecularFunctionaminophospholipid flippase activity

ATP11C ATP8B1

1.55e-047552GO:0015247
GeneOntologyMolecularFunctionphosphatidylserine floppase activity

ATP11C ATP8B1

2.65e-049552GO:0090556
GeneOntologyMolecularFunction2-acylglycerol-3-phosphate O-acyltransferase activity

MBOAT7 MBOAT2

2.65e-049552GO:0047144
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

NALCN SCN1A SCN3A SCN8A SCN9A KCNQ2 ATP1B2

2.74e-04465557GO:0046873
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A TMEM63B KCNQ2 ATP1B2

2.89e-04793559GO:0015075
GeneOntologyMolecularFunctionNAD(P)H oxidase H2O2-forming activity

NOX1 NOX4

4.83e-0412552GO:0016174
GeneOntologyMolecularFunctionammonium channel activity

RHCE RHD

4.83e-0412552GO:0008519
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ATP11C ATP8B1

6.64e-0414552GO:0140333
GeneOntologyMolecularFunctionfloppase activity

ATP11C ATP8B1

8.72e-0416552GO:0140328
GeneOntologyMolecularFunctionflippase activity

ATP11C ATP8B1

9.87e-0417552GO:0140327
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GPR61 OR52A4P P2RX7 MRGPRE MFSD6 TMEM63B ADGRF4 OPN1SW VN1R1 NPFFR1 ADCYAP1R1

9.98e-0413535511GO:0004888
GeneOntologyMolecularFunctiontetrapyrrole binding

CYBB NOX4 NOX3 LMBRD1

1.08e-03164554GO:0046906
GeneOntologyMolecularFunction1-acylglycerol-3-phosphate O-acyltransferase activity

MBOAT7 MBOAT2

1.51e-0321552GO:0003841
GeneOntologyMolecularFunctionlysophosphatidic acid acyltransferase activity

MBOAT7 MBOAT2

1.98e-0324552GO:0042171
GeneOntologyMolecularFunctionlysophospholipid acyltransferase activity

MBOAT7 MBOAT2

1.98e-0324552GO:0071617
GeneOntologyMolecularFunctionlipid transporter activity

ABCC1 ATP11C ATP8B1 ABCA10

2.08e-03196554GO:0005319
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ATP11C ATP8B1

2.69e-0328552GO:0140326
GeneOntologyMolecularFunctionG protein-coupled receptor activity

GPR61 OR52A4P MRGPRE ADGRF4 OPN1SW VN1R1 NPFFR1 ADCYAP1R1

2.75e-03884558GO:0004930
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCC1 ATP1B2 ABCA10

3.38e-03109553GO:0042626
GeneOntologyMolecularFunctionacylglycerol O-acyltransferase activity

MBOAT7 MBOAT2

3.50e-0332552GO:0016411
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

ABCC1 SLC25A26

3.72e-0333552GO:0072349
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC1 ABCA10

8.06e-0349552GO:0140359
GeneOntologyMolecularFunctionmolecular sensor activity

TMEM63B NOX4

8.38e-0350552GO:0140299
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ATP11C ATP8B1

8.71e-0351552GO:0140303
GeneOntologyMolecularFunctionheme binding

CYBB NOX4 NOX3

8.80e-03154553GO:0020037
GeneOntologyBiologicalProcessneuronal action potential

P2RX7 SCN1A SCN3A SCN8A SCN9A KCNQ2

1.31e-0863536GO:0019228
GeneOntologyBiologicalProcessphospholipid translocation

ABCC1 P2RX7 ATP11C ATP8B1 XKR5

2.91e-0755535GO:0045332
GeneOntologyBiologicalProcesstransmission of nerve impulse

P2RX7 SCN1A SCN3A SCN8A SCN9A KCNQ2

4.18e-07112536GO:0019226
GeneOntologyBiologicalProcesslipid translocation

ABCC1 P2RX7 ATP11C ATP8B1 XKR5

4.53e-0760535GO:0034204
GeneOntologyBiologicalProcesssodium ion transport

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A KCNQ2 ATP1B2

4.76e-07275538GO:0006814
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CYBB ABCC1 NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A TMEM63B KCNQ2 ATP11C ATP8B1 ATP1B2 ADCYAP1R1

5.55e-0711155314GO:0034220
GeneOntologyBiologicalProcessmembrane depolarization

P2RX7 SCN1A SCN3A SCN8A SCN9A KCNQ2

6.59e-07121536GO:0051899
GeneOntologyBiologicalProcessregulation of membrane lipid distribution

ABCC1 P2RX7 ATP11C ATP8B1 XKR5

6.79e-0765535GO:0097035
GeneOntologyBiologicalProcesssodium ion transmembrane transport

NALCN SCN1A SCN3A SCN8A SCN9A KCNQ2 ATP1B2

9.97e-07208537GO:0035725
GeneOntologyBiologicalProcessmonoatomic ion transport

CYBB ABCC1 NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A TMEM63B KCNQ2 ATP11C ATP8B1 SLC25A26 ATP1B2 ADCYAP1R1

1.18e-0613745315GO:0006811
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN1A SCN3A SCN8A SCN9A

2.15e-0636534GO:0086010
GeneOntologyBiologicalProcessphospholipid transport

ABCC1 P2RX7 ATP11C ATP8B1 XKR5

7.69e-06106535GO:0015914
GeneOntologyBiologicalProcesssuperoxide anion generation

CYBB NOX1 NOX4 NOX3

8.20e-0650534GO:0042554
GeneOntologyBiologicalProcessaction potential

P2RX7 SCN1A SCN3A SCN8A SCN9A KCNQ2

1.25e-05201536GO:0001508
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A KCNQ2 ATP1B2 ADCYAP1R1 RHCE RHD

1.82e-059225311GO:0098662
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN1A SCN3A SCN8A SCN9A

1.94e-0562534GO:0086002
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

SCN1A SCN8A SCN9A TMEM63B KCNQ2 ATP8B1

3.23e-05238536GO:0050954
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A KCNQ2 ATP1B2 ADCYAP1R1 RHCE RHD

4.49e-0510175311GO:0098660
GeneOntologyBiologicalProcessorganophosphate ester transport

ABCC1 P2RX7 ATP11C ATP8B1 XKR5

5.95e-05162535GO:0015748
GeneOntologyBiologicalProcesssuperoxide metabolic process

CYBB NOX1 NOX4 NOX3

6.14e-0583534GO:0006801
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN1A SCN3A SCN8A SCN9A

7.38e-0587534GO:0086001
GeneOntologyBiologicalProcessregulation of membrane potential

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A KCNQ2 ATP1B2

8.38e-05559538GO:0042391
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN1A SCN3A SCN8A SCN9A

9.58e-0593534GO:0086003
GeneOntologyBiologicalProcessammonium homeostasis

RHCE RHD

9.65e-056532GO:0097272
GeneOntologyBiologicalProcessreactive oxygen species metabolic process

CYBB PLA2R1 NOX1 P2RX7 NOX4 NOX3

9.85e-05291536GO:0072593
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A TMEM63B KCNQ2 ATP1B2 ADCYAP1R1

1.23e-049425310GO:0098655
GeneOntologyBiologicalProcessaminophospholipid translocation

ATP11C ATP8B1

1.35e-047532GO:0140331
GeneOntologyBiologicalProcessheart process

SCN1A SCN3A SCN8A SCN9A NOX4 ATP1B2

1.37e-04309536GO:0003015
GeneOntologyBiologicalProcessnerve development

SCN1A SCN8A KCNQ2 ATP8B1

1.77e-04109534GO:0021675
GeneOntologyBiologicalProcessSRP-dependent cotranslational protein targeting to membrane, translocation

TRAM1L1 TRAM1

1.80e-048532GO:0006616
GeneOntologyBiologicalProcessaminophospholipid transport

ATP11C ATP8B1

2.31e-049532GO:0015917
GeneOntologyBiologicalProcesslipid transport

ABCC1 PLA2R1 P2RX7 ATP11C ATP8B1 ABCA10 XKR5

2.98e-04506537GO:0006869
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN1A SCN3A SCN8A SCN9A

3.18e-04127534GO:0070252
GeneOntologyBiologicalProcesssensory perception

OR52A4P P2RX7 SCN1A SCN8A SCN9A TMEM63B KCNQ2 ATP8B1 OPN1SW VN1R1

3.49e-0410725310GO:0007600
GeneOntologyBiologicalProcesserythrocyte development

ADGRF4 RHCE RHD

3.82e-0455533GO:0048821
GeneOntologyBiologicalProcessammonium transmembrane transport

RHCE RHD

4.96e-0413532GO:0072488
GeneOntologyBiologicalProcesscirculatory system process

ABCC1 NOX1 SCN1A SCN3A SCN8A SCN9A NOX4 ATP1B2

5.27e-04733538GO:0003013
GeneOntologyBiologicalProcesslipid localization

ABCC1 PLA2R1 P2RX7 ATP11C ATP8B1 ABCA10 XKR5

5.77e-04565537GO:0010876
GeneOntologyBiologicalProcessphosphatidylcholine acyl-chain remodeling

MBOAT7 MBOAT2

5.78e-0414532GO:0036151
GeneOntologyBiologicalProcessmonoatomic cation transport

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A TMEM63B KCNQ2 ATP1B2 ADCYAP1R1

6.36e-0411575310GO:0006812
GeneOntologyBiologicalProcessactin filament-based movement

SCN1A SCN3A SCN8A SCN9A

6.43e-04153534GO:0030048
GeneOntologyBiologicalProcesshydrogen peroxide metabolic process

CYBB NOX1 NOX4

6.83e-0467533GO:0042743
GeneOntologyBiologicalProcessicosanoid transport

ABCC1 PLA2R1 P2RX7

8.78e-0473533GO:0071715
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN1A SCN3A SCN8A SCN9A

8.91e-04167534GO:0060048
GeneOntologyBiologicalProcessmetal ion transport

NALCN P2RX7 SCN1A SCN3A SCN8A SCN9A KCNQ2 ATP1B2 ADCYAP1R1

9.23e-041000539GO:0030001
GeneOntologyBiologicalProcessheart contraction

SCN1A SCN3A SCN8A SCN9A ATP1B2

9.91e-04298535GO:0060047
GeneOntologyBiologicalProcessdetection of external stimulus

SCN1A SCN9A NOX3 OPN1SW

1.02e-03173534GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

SCN1A SCN9A NOX3 OPN1SW

1.06e-03175534GO:0009582
GeneOntologyBiologicalProcesspositive regulation of calcium ion transport into cytosol

P2RX7 ADCYAP1R1

1.32e-0321532GO:0010524
GeneOntologyBiologicalProcessplasma membrane organization

NOX1 P2RX7 ATP8B1 XKR5

1.38e-03188534GO:0007009
GeneOntologyBiologicalProcesshydrogen peroxide biosynthetic process

CYBB NOX4

1.45e-0322532GO:0050665
GeneOntologyBiologicalProcessmulticellular organismal-level chemical homeostasis

TMEM63B RHCE RHD

1.61e-0390533GO:0140962
GeneOntologyBiologicalProcesssensory perception of sound

SCN8A TMEM63B KCNQ2 ATP8B1

1.67e-03198534GO:0007605
GeneOntologyBiologicalProcesspositive regulation of icosanoid secretion

PLA2R1 P2RX7

1.72e-0324532GO:0032305
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN3A SCN8A SCN9A

9.95e-0817554GO:0001518
GeneOntologyCellularComponentNADPH oxidase complex

CYBB NOX1 NOX4 NOX3

1.28e-0718554GO:0043020
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN3A SCN8A SCN9A

9.70e-0729554GO:0034706
GeneOntologyCellularComponenttransporter complex

CYBB NALCN SCN1A SCN3A SCN8A SCN9A KCNQ2 ATP11C ATP8B1 ATP1B2

1.48e-065505510GO:1990351
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN8A KCNQ2

1.90e-0520553GO:0033268
GeneOntologyCellularComponentplasma membrane protein complex

CYBB NOX1 SCN1A SCN3A SCN8A SCN9A KCNQ2 NOX4 NOX3 ATP1B2

3.33e-057855510GO:0098797
GeneOntologyCellularComponentmonoatomic ion channel complex

CYBB NALCN SCN1A SCN3A SCN8A SCN9A KCNQ2

5.75e-05378557GO:0034702
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN8A KCNQ2

6.00e-0529553GO:0043194
GeneOntologyCellularComponenttransmembrane transporter complex

CYBB NALCN SCN1A SCN3A SCN8A SCN9A KCNQ2 ATP1B2

6.30e-05523558GO:1902495
GeneOntologyCellularComponentmembrane protein complex

CYBB NOX1 NALCN SCN1A SCN3A SCN8A SCN9A KCNQ2 NOX4 NOX3 ATP1B2 RHCE RHD

1.06e-0414985513GO:0098796
GeneOntologyCellularComponentankyrin-1 complex

RHCE RHD

3.02e-0410552GO:0170014
GeneOntologyCellularComponentcation channel complex

SCN1A SCN3A SCN8A SCN9A KCNQ2

3.79e-04235555GO:0034703
GeneOntologyCellularComponentendoplasmic reticulum membrane

CYBB TRAM1L1 MBOAT7 TRAM1 SPPL3 UGT2B15 NOX4 ALG8 ATP11C MBOAT2 LMBRD1

4.67e-0412935511GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

CYBB TRAM1L1 MBOAT7 TRAM1 SPPL3 UGT2B15 NOX4 ALG8 ATP11C MBOAT2 LMBRD1

4.86e-0412995511GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

CYBB TRAM1L1 MBOAT7 TRAM1 SPPL3 UGT2B15 NOX4 ALG8 ATP11C MBOAT2 LMBRD1

5.82e-0413275511GO:0042175
GeneOntologyCellularComponentphospholipid-translocating ATPase complex

ATP11C ATP8B1

6.06e-0414552GO:1990531
GeneOntologyCellularComponentoxidoreductase complex

CYBB NOX1 NOX4 NOX3

8.52e-04161554GO:1990204
GeneOntologyCellularComponentmain axon

SCN1A SCN8A KCNQ2

1.67e-0389553GO:0044304
GeneOntologyCellularComponentperinuclear endoplasmic reticulum

CYBB NOX4

2.64e-0329552GO:0097038
GeneOntologyCellularComponentlumenal side of endoplasmic reticulum membrane

SPPL3 ALG8

3.83e-0335552GO:0098553
HumanPhenoFocal hemiclonic seizure

SCN1A SCN8A SCN9A KCNQ2

2.07e-0625204HP:0006813
HumanPhenoSimple febrile seizure

SCN1A SCN3A SCN8A KCNQ2

2.86e-0627204HP:0011171
HumanPhenoGeneralized clonic seizure

SCN1A SCN8A SCN9A KCNQ2

7.43e-0634204HP:0011169
HumanPhenoFocal automatism seizure

SCN1A SCN8A KCNQ2

1.11e-0512203HP:0032898
HumanPhenoClonic seizure

SCN1A SCN3A SCN8A SCN9A KCNQ2

1.15e-0581205HP:0020221
HumanPhenoInfection-related seizure

MBOAT7 SCN1A SCN3A SCN8A SCN9A KCNQ2

1.34e-05145206HP:0032892
HumanPhenoSeizure precipitated by febrile infection

MBOAT7 SCN1A SCN3A SCN8A SCN9A KCNQ2

1.34e-05145206HP:0032894
HumanPhenoFebrile seizure (within the age range of 3 months to 6 years)

MBOAT7 SCN1A SCN3A SCN8A SCN9A KCNQ2

1.34e-05145206HP:0002373
HumanPhenoDermatological manifestations of systemic disorders

CYBB SCN1A SCN8A SCN9A KCNQ2 ATP11C ATP8B1 RHCE RHD

1.59e-05435209HP:0001005
HumanPhenoFocal clonic seizure

SCN1A SCN8A SCN9A KCNQ2

1.76e-0542204HP:0002266
HumanPhenoFacial tics

SCN1A SCN9A KCNQ2

2.29e-0515203HP:0011468
HumanPhenoComplex febrile seizure

SCN1A SCN8A SCN9A

2.81e-0516203HP:0011172
HumanPhenoAnti-erythrocyte autoantibody positivity

RHCE RHD

4.38e-053202HP:6000388
HumanPhenoPositive direct antiglobulin test

RHCE RHD

4.38e-053202HP:0032366
HumanPhenoGeneralized tonic seizure

SCN1A SCN8A SCN9A KCNQ2

9.44e-0564204HP:0010818
HumanPhenoFocal impaired awareness seizure

SCN1A SCN3A SCN8A SCN9A KCNQ2

9.84e-05126205HP:0002384
HumanPhenoMultifocal epileptiform discharges

SCN1A SCN8A SCN9A KCNQ2

1.07e-0466204HP:0010841
HumanPhenoEpileptic aura

SCN1A SCN8A KCNQ2

1.13e-0425203HP:0033348
HumanPhenoFocal head nodding automatism seizure

SCN8A KCNQ2

1.45e-045202HP:0032906
HumanPhenoNeonatal electro-clinical non-motor seizure

SCN8A KCNQ2

1.45e-045202HP:0032812
HumanPhenoNeonatal seizure with electrographic correlate

SCN8A KCNQ2

1.45e-045202HP:0032808
HumanPhenoNeonatal electro-clinical seizure

SCN8A KCNQ2

1.45e-045202HP:0032809
HumanPhenoNeonatal electro-clinical seizure with behavior arrest

SCN8A KCNQ2

1.45e-045202HP:0032823
HumanPhenoGeneralized myoclonic seizure

MBOAT7 SCN1A SCN8A SCN9A KCNQ2

2.11e-04148205HP:0002123
HumanPhenoNormal interictal EEG

SCN8A KCNQ2

2.18e-046202HP:0002372
HumanPhenoCalcaneovalgus deformity

NALCN SCN1A SCN9A

2.87e-0434203HP:0001848
HumanPhenoEyelid myoclonia seizure

SCN8A KCNQ2

3.04e-047202HP:0032678
HumanPhenoAbnormality of taste sensation

TRANK1 SCN9A

3.04e-047202HP:0000223
HumanPhenoDeformed tarsal bones

NALCN SCN1A SCN9A

3.13e-0435203HP:0008119
HumanPhenoDisturbance of facial expression

SCN1A SCN9A KCNQ2

3.40e-0436203HP:0005324
HumanPhenoSpherocytosis

RHCE RHD

4.04e-048202HP:0004444
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN9A

4.04e-048202HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN9A

4.04e-048202HP:0200048
HumanPhenoFocal non-motor seizure

SCN1A SCN8A KCNQ2

4.66e-0440203HP:0032679
HumanPhenoSudden unexpected death in epilepsy

SCN1A SCN8A

6.47e-0410202HP:0033258
HumanPhenoFocal autonomic seizure

SCN8A KCNQ2

7.89e-0411202HP:0011154
HumanPhenoLimited neck range of motion

SCN1A SCN9A

7.89e-0411202HP:0000466
HumanPhenoNeonatal seizure

SCN8A KCNQ2

7.89e-0411202HP:0032807
HumanPhenoAbnormal fetal physiology

NALCN SCN3A SCN8A ALG8 ATP8B1 SLC25A26

8.75e-04308206HP:0034059
HumanPhenoEpilepsia partialis continua

SCN1A SCN9A

9.44e-0412202HP:0012847
HumanPhenoHypochromia

RHCE RHD

9.44e-0412202HP:0032231
HumanPhenoCyanosis

SCN1A SCN8A SCN9A KCNQ2

9.64e-04117204HP:0000961
HumanPhenoStatus epilepticus

SCN1A SCN3A SCN8A SCN9A KCNQ2

9.93e-04207205HP:0002133
HumanPhenoEEG with focal epileptiform discharges

SCN1A SCN8A SCN9A KCNQ2

9.95e-04118204HP:0011185
HumanPhenoBilateral tonic-clonic seizure with focal onset

SCN1A SCN8A KCNQ2

1.01e-0352203HP:0007334
HumanPhenoEpileptic encephalopathy

SCN1A SCN3A SCN8A KCNQ2

1.03e-03119204HP:0200134
HumanPhenoIncreased red cell osmotic fragility

RHCE RHD

1.11e-0313202HP:0005502
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN9A

1.11e-0313202HP:0007058
HumanPhenoStomatocytosis

RHCE RHD

1.30e-0314202HP:0004446
HumanPhenoAbnormality of the calcaneus

NALCN SCN1A SCN9A

1.32e-0357203HP:0008364
HumanPhenoFocal motor seizure

SCN1A SCN8A SCN9A KCNQ2

1.47e-03131204HP:0011153
HumanPhenoAortopulmonary collateral arteries

SCN1A KCNQ2

1.49e-0315202HP:0031834
HumanPhenoAbnormal erythrocyte physiology

RHCE RHD

1.49e-0315202HP:0020054
HumanPhenoPhotosensitive tonic-clonic seizure

SCN1A SCN9A

1.49e-0315202HP:0007207
HumanPhenoReduced haptoglobin level

RHCE RHD

1.49e-0315202HP:0020181
HumanPhenoGeneralized-onset motor seizure

MBOAT7 SCN1A SCN8A SCN9A KCNQ2

1.53e-03228205HP:0032677
HumanPhenoAscites

CYBB ALG8 ATP8B1 RHD

1.60e-03134204HP:0001541
HumanPhenoFocal-onset seizure

MBOAT7 SCN1A SCN3A SCN8A SCN9A KCNQ2

1.61e-03346206HP:0007359
HumanPhenoDysgenesis of the hippocampus

SCN1A SCN9A

1.70e-0316202HP:0025101
HumanPhenoAbnormal circulating haptoglobin concentration

RHCE RHD

1.70e-0316202HP:0020179
HumanPhenoTonic seizure

SCN1A SCN8A SCN9A KCNQ2

1.88e-03140204HP:0032792
HumanPhenoAtypical absence status epilepticus

SCN1A SCN9A

1.92e-0317202HP:0011151
HumanPhenoFocal motor status epilepticus

SCN1A SCN9A

1.92e-0317202HP:0032663
HumanPhenoFocal emotional seizure with laughing

SCN1A KCNQ2

1.92e-0317202HP:0010821
HumanPhenoPrenatal movement abnormality

NALCN SCN3A SCN8A ALG8 SLC25A26

2.15e-03246205HP:0001557
HumanPhenoVisually-induced seizure

SCN1A SCN9A

2.16e-0318202HP:0020216
HumanPhenoGeneralized non-convulsive status epilepticus without coma

SCN1A SCN9A

2.16e-0318202HP:0032860
HumanPhenoFocal emotional seizure

SCN1A KCNQ2

2.16e-0318202HP:0025613
HumanPhenoAbnormality of the amniotic fluid

NALCN SCN8A ALG8 ATP8B1 SLC25A26 RHCE RHD

2.19e-03504207HP:0001560
HumanPhenoDialeptic seizure

SCN1A SCN3A SCN8A SCN9A KCNQ2

2.35e-03251205HP:0011146
HumanPhenoImpulsivity

SCN1A SCN3A SCN8A SCN9A

2.36e-03149204HP:0100710
DomainCyt_b245_heavy_chain

CYBB NOX1 NOX4 NOX3

7.25e-114564IPR000778
DomainNa_trans_cytopl

SCN1A SCN3A SCN8A SCN9A

1.08e-096564PF11933
DomainNa_trans_cytopl

SCN1A SCN3A SCN8A SCN9A

1.08e-096564IPR024583
DomainNAD_binding_6

CYBB NOX1 NOX4 NOX3

2.52e-097564PF08030
DomainFAD-bd_8

CYBB NOX1 NOX4 NOX3

2.52e-097564IPR013112
DomainFe_red_NAD-bd_6

CYBB NOX1 NOX4 NOX3

2.52e-097564IPR013121
DomainFAD_binding_8

CYBB NOX1 NOX4 NOX3

2.52e-097564PF08022
DomainNa_channel_asu

SCN1A SCN3A SCN8A SCN9A

1.50e-0810564IPR001696
DomainNa_trans_assoc

SCN1A SCN3A SCN8A SCN9A

1.50e-0810564IPR010526
DomainNa_trans_assoc

SCN1A SCN3A SCN8A SCN9A

1.50e-0810564PF06512
DomainFe3_Rdtase_TM_dom

CYBB NOX1 NOX4 NOX3

3.52e-0812564IPR013130
DomainFerric_reduct

CYBB NOX1 NOX4 NOX3

3.52e-0812564PF01794
DomainFd_Rdtase_FAD-bd

CYBB NOX1 NOX4 NOX3

2.72e-0719564IPR017927
DomainFAD_FR

CYBB NOX1 NOX4 NOX3

2.72e-0719564PS51384
DomainRiboflavin_synthase-like_b-brl

CYBB NOX1 NOX4 NOX3

2.72e-0719564IPR017938
DomainChannel_four-helix_dom

NALCN SCN1A SCN3A SCN8A SCN9A

7.51e-0757565IPR027359
Domain-

NALCN SCN1A SCN3A SCN8A SCN9A

7.51e-07575651.20.120.350
DomainIon_trans_dom

NALCN SCN1A SCN3A SCN8A SCN9A KCNQ2

1.15e-06114566IPR005821
DomainIon_trans

NALCN SCN1A SCN3A SCN8A SCN9A KCNQ2

1.15e-06114566PF00520
DomainTLC

TRAM1L1 TRAM1 TLCD4

1.39e-0516563PS50922
DomainTRAM_LAG1_CLN8

TRAM1L1 TRAM1 TLCD4

1.39e-0516563PF03798
DomainTLC-dom

TRAM1L1 TRAM1 TLCD4

1.39e-0516563IPR006634
DomainTLC

TRAM1L1 TRAM1 TLCD4

1.39e-0516563SM00724
DomainTranslocation_assoc_membrane

TRAM1L1 TRAM1

2.64e-053562IPR016447
DomainTRAM1

TRAM1L1 TRAM1

2.64e-053562PF08390
DomainTRAM1

TRAM1L1 TRAM1

2.64e-053562IPR013599
DomainIQ

SCN1A SCN3A SCN8A SCN9A

6.07e-0571564PF00612
DomainAmmonium_transpt

RHCE RHD

8.78e-055562IPR001905
DomainAmmonium_transp

RHCE RHD

8.78e-055562PF00909
DomainNH4_transpt_AmtB-like_dom

RHCE RHD

8.78e-055562IPR024041
DomainRhesusRHD

RHCE RHD

8.78e-055562IPR002229
DomainIQ

SCN1A SCN3A SCN8A SCN9A

1.02e-0481564SM00015
DomainIQ_motif_EF-hand-BS

SCN1A SCN3A SCN8A SCN9A

1.53e-0490564IPR000048
DomainIQ

SCN1A SCN3A SCN8A SCN9A

1.74e-0493564PS50096
Domain-

RHCE RHD

1.84e-0475621.10.3430.10
DomainAmmonium/urea_transptr

RHCE RHD

1.84e-047562IPR029020
DomainMBOAT_fam

MBOAT7 MBOAT2

4.77e-0411562IPR004299
DomainAdipoR/HlyIII-related

PAQR9 PAQR8

4.77e-0411562IPR004254
DomainMBOAT

MBOAT7 MBOAT2

4.77e-0411562PF03062
DomainHlyIII

PAQR9 PAQR8

4.77e-0411562PF03006
DomainP_typ_ATPase_c

ATP11C ATP8B1

7.85e-0414562IPR032630
DomainP-type_ATPase_N

ATP11C ATP8B1

7.85e-0414562IPR032631
DomainP-type_ATPase_IV

ATP11C ATP8B1

7.85e-0414562IPR006539
DomainPhoLip_ATPase_C

ATP11C ATP8B1

7.85e-0414562PF16212
DomainPhoLip_ATPase_N

ATP11C ATP8B1

7.85e-0414562PF16209
DomainEF-hand-dom_pair

SCN1A SCN3A SCN8A SCN9A FKBP7

1.67e-03287565IPR011992
Domain-

ATP11C ATP8B1

4.13e-03325622.70.150.10
Domain-

ATP11C ATP8B1

4.13e-03325623.40.1110.10
DomainATPase_P-typ_cyto_domN

ATP11C ATP8B1

4.93e-0335562IPR023299
DomainATPase_P-typ_P_site

ATP11C ATP8B1

5.21e-0336562IPR018303
DomainP_typ_ATPase

ATP11C ATP8B1

5.21e-0336562IPR001757
DomainATPASE_E1_E2

ATP11C ATP8B1

5.21e-0336562PS00154
DomainATPase_P-typ_transduc_dom_A

ATP11C ATP8B1

5.50e-0337562IPR008250
DomainE1-E2_ATPase

ATP11C ATP8B1

5.50e-0337562PF00122
DomainG_PROTEIN_RECEP_F2_1

ADGRF4 ADCYAP1R1

6.40e-0340562PS00649
DomainG_PROTEIN_RECEP_F2_3

ADGRF4 ADCYAP1R1

6.40e-0340562PS50227
DomainGPCR_2_extracellular_dom

ADGRF4 ADCYAP1R1

6.40e-0340562IPR001879
DomainABC_transporter_CS

ABCC1 ABCA10

7.04e-0342562IPR017871
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1A SCN3A SCN8A SCN9A KCNQ2

2.60e-0831415M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1A SCN3A SCN8A SCN9A

2.09e-0632414M27455
PathwayWP_OXIDATIVE_STRESS_RESPONSE

CYBB NOX1 NOX4 NOX3

2.37e-0633414M39645
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

NOX1 SCN1A SCN3A SCN8A SCN9A NOX4 NOX3 LMBRD1

8.81e-06367418M48346
PathwayREACTOME_L1CAM_INTERACTIONS

SCN1A SCN3A SCN8A SCN9A KCNQ2

2.51e-05121415M872
PathwayREACTOME_CARDIAC_CONDUCTION

SCN1A SCN3A SCN8A SCN9A ATP1B2

3.55e-05130415M27454
PathwayREACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES

CYBB NOX1 NOX3

4.43e-0524413M27553
PathwayREACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES

CYBB NOX1 NOX3

5.02e-0525413MM15269
PathwayWP_DRAVET_SYNDROME

SCN1A SCN3A SCN8A

7.11e-0528413M45519
PathwayREACTOME_TRANSPORT_OF_RCBL_WITHIN_THE_BODY

ABCC1 LMBRD1

1.72e-047412MM15703
PathwayREACTOME_TRANSPORT_OF_RCBL_WITHIN_THE_BODY

ABCC1 LMBRD1

2.29e-048412M45025
PathwayREACTOME_MUSCLE_CONTRACTION

SCN1A SCN3A SCN8A SCN9A ATP1B2

2.90e-04203415M5485
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP11C ATP8B1 ATP1B2

5.39e-0455413M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP11C ATP8B1 ATP1B2

5.99e-0457413MM15643
PathwayWP_FERROPTOSIS

CYBB NOX1 NOX4

8.41e-0464413M39768
PathwayREACTOME_COBALAMIN_CBL_VITAMIN_B12_TRANSPORT_AND_METABOLISM

ABCC1 LMBRD1

8.46e-0415412MM14762
PathwayWP_GPCRS_ODORANT

GPR61 MRGPRE ADGRF4 OPN1SW

1.09e-03157414MM15872
PathwayREACTOME_ACYL_CHAIN_REMODELLING_OF_PI

PLA2R1 MBOAT7

1.09e-0317412MM14580
PathwayREACTOME_ACYL_CHAIN_REMODELLING_OF_PI

PLA2R1 MBOAT7

1.09e-0317412M626
PathwayREACTOME_ION_CHANNEL_TRANSPORT

NALCN ATP11C ATP8B1 ATP1B2

1.66e-03176414MM15718
PathwayREACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS

RHCE RHD

1.67e-0321412M27917
PathwayREACTOME_COBALAMIN_CBL_VITAMIN_B12_TRANSPORT_AND_METABOLISM

ABCC1 LMBRD1

1.84e-0322412M27084
PathwayREACTOME_ION_CHANNEL_TRANSPORT

NALCN ATP11C ATP8B1 ATP1B2

1.91e-03183414M997
PathwayREACTOME_RAC3_GTPASE_CYCLE

CYBB NOX1 NOX3

2.47e-0393413MM15609
PathwayREACTOME_RAC3_GTPASE_CYCLE

CYBB NOX1 NOX3

2.55e-0394413M41818
PathwayREACTOME_ACYL_CHAIN_REMODELLING_OF_PC

PLA2R1 MBOAT2

2.77e-0327412M643
PathwayREACTOME_ACYL_CHAIN_REMODELLING_OF_PE

PLA2R1 MBOAT2

2.97e-0328412MM14578
PathwayREACTOME_ACYL_CHAIN_REMODELLING_OF_PC

PLA2R1 MBOAT2

2.97e-0328412MM14575
PathwayREACTOME_PARACETAMOL_ADME

ABCC1 UGT2B15

3.19e-0329412M45015
PathwayREACTOME_ACYL_CHAIN_REMODELLING_OF_PE

PLA2R1 MBOAT2

3.19e-0329412M702
Pubmed

Constitutive NADPH oxidase 4 activity resides in the composition of the B-loop and the penultimate C terminus.

CYBB NOX1 NOX4 NOX3

6.03e-12456422277655
Pubmed

Transfer of intracellular HIV Nef to endothelium causes endothelial dysfunction.

CYBB NOX1 NOX4 NOX3

3.01e-11556424608713
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN3A SCN8A SCN9A

9.02e-11656423652591
Pubmed

The NADPH oxidase NOX4 drives cardiac differentiation: Role in regulating cardiac transcription factors and MAP kinase activation.

CYBB NOX1 NOX4 NOX3

9.02e-11656416775014
Pubmed

Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase.

CYBB NOX1 NOX4 NOX3

2.10e-10756419005069
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN3A SCN8A SCN9A

7.55e-10956416382098
Pubmed

NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion.

CYBB NOX1 NOX4

3.95e-09356322933115
Pubmed

Intrarenal artery superoxide is mainly NADPH oxidase-derived and modulates endothelium-dependent dilation in elderly patients.

CYBB NOX1 NOX4

3.95e-09356319843513
Pubmed

Development of an improved and specific inhibitor of NADPH oxidase 2 to treat traumatic brain injury.

CYBB NOX1 NOX4

3.95e-09356336709665
Pubmed

The NADPH Oxidase Nox2 Mediates Vitamin D-Induced Vascular Regeneration in Male Mice.

CYBB NOX1 NOX4

3.95e-09356327399878
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A SCN9A

3.95e-09356333895391
Pubmed

Perturbation of ubiquitin homeostasis promotes macrophage oxidative defenses.

CYBB NOX1 NOX4

3.95e-09356331308397
Pubmed

Genetic deletion of Nox4 enhances cancerogen-induced formation of solid tumors.

CYBB NOX1 NOX4

3.95e-09356333836590
Pubmed

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.

CYBB NOX1 NOX4

3.95e-09356320877715
Pubmed

Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase.

CYBB NOX1 NOX4

3.95e-09356322456182
Pubmed

A constitutive NADPH oxidase-like system containing gp91phox homologs in human keratinocytes.

CYBB NOX1 NOX4

3.95e-09356315102091
Pubmed

NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis.

CYBB NOX1 NOX4

3.95e-09356333267663
Pubmed

NADPH oxidase subunit, gp91(phox) homologue, preferentially expressed in human colon epithelial cells.

CYBB NOX1 NOX3

3.95e-09356310974555
Pubmed

Differential expression of NADPH oxidases in megakaryocytes and their role in polyploidy.

CYBB NOX1 NOX4

3.95e-09356319471020
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN3A SCN8A SCN9A

4.26e-091356415123669
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN3A SCN8A

1.58e-08456317537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN3A SCN8A

1.58e-08456335031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN3A SCN8A

1.58e-08456329578003
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN8A KCNQ2

1.58e-08456321156207
Pubmed

Models for discovery of targeted therapy in genetic epileptic encephalopathies.

SCN1A SCN8A KCNQ2

1.58e-08456328742937
Pubmed

Cyba-deficient mice display an increase in hematopoietic stem cells and an overproduction of immunoglobulins.

CYBB NOX1 NOX4

1.58e-08456331919083
Pubmed

Amplification of the inflammatory cellular redox state by human immunodeficiency virus type 1-immunosuppressive tat and gp160 proteins.

NOX1 NOX4 NOX3

1.58e-0845639882350
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN3A SCN9A

3.94e-0855638812438
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN3A SCN8A SCN9A

3.94e-08556322875929
Pubmed

Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins.

CYBB NOX1 NOX4

3.94e-08556315256399
Pubmed

Macrophage-specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1/MMP-9 pathways.

CYBB NOX1 NOX4

3.94e-08556325116588
Pubmed

Impaired OXPHOS complex III in breast cancer.

CYBB NOX4 NOX3

3.94e-08556321901141
Pubmed

Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice.

CYBB NOX1 NOX4

3.94e-08556322337127
Pubmed

NOX isoforms in the development of abdominal aortic aneurysm.

CYBB NOX1 NOX4

7.88e-08656327912196
Pubmed

The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye.

CYBB NOX1 NOX4

7.88e-08656332483169
Pubmed

APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury.

CYBB NOX1 NOX4

7.88e-08656328165467
Pubmed

Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury.

CYBB NOX1 NOX4

7.88e-08656324051369
Pubmed

Cooperative induction of CXCL10 involves NADPH oxidase: Implications for HIV dementia.

NOX1 NOX4 NOX3

7.88e-08656319941336
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

P2RX7 SCN1A SCN3A SCN8A SCN9A KCNQ2

1.01e-0713956616985003
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN8A KCNQ2

1.38e-07756325818041
Pubmed

Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase.

NOX1 NOX4 NOX3

3.30e-07956315509740
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN3A SCN8A

3.30e-07956315746173
Pubmed

Control of hepatic nuclear superoxide production by glucose 6-phosphate dehydrogenase and NADPH oxidase-4.

CYBB NOX1 NOX4

4.71e-071056321212270
Pubmed

Mitochondrial reactive oxygen species enable proinflammatory signaling through disulfide linkage of NEMO.

CYBB NOX1 NOX4

6.46e-071156330755476
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN3A SCN8A

8.61e-071256330175250
Pubmed

Organization of the gene (RHCE) encoding the human blood group RhCcEe antigens and characterization of the promoter region.

RHCE RHD

2.55e-0625628188244
Pubmed

Homocysteine-induced apoptosis in endothelial cells coincides with nuclear NOX2 and peri-nuclear NOX4 activity.

CYBB NOX4

2.55e-06256222038300
Pubmed

Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-kappaB in human aortic smooth muscle cells.

NOX1 NOX4

2.55e-06256220457132
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

2.55e-06256237901435
Pubmed

E variants found in Japanese and c antigenicity alteration without substitution in the second extracellular loop.

RHCE RHD

2.55e-06256211724987
Pubmed

NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

NOX1 NOX4

2.55e-06256220715105
Pubmed

Adverse cognitive effects of high-fat diet in a murine model of sleep apnea are mediated by NADPH oxidase activity.

CYBB NOX1

2.55e-06256223064009
Pubmed

Netrin-1 abrogates ischemia/reperfusion-induced cardiac mitochondrial dysfunction via nitric oxide-dependent attenuation of NOX4 activation and recoupling of NOS.

CYBB NOX1

2.55e-06256225066694
Pubmed

DCS-1, DCS-2, and DFV share amino acid substitutions at the extracellular RhD protein vestibule.

RHCE RHD

2.55e-06256217900276
Pubmed

RHD and RHCE molecular analysis in weak D blood donors and in patients with Rh antibodies against their own corresponding Rh antigen.

RHCE RHD

2.55e-06256232697929
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

2.55e-06256226410685
Pubmed

The Rh blood group system: a review.

RHCE RHD

2.55e-06256210627438
Pubmed

NADPH-oxidase 4 protects against kidney fibrosis during chronic renal injury.

CYBB NOX4

2.55e-06256223100220
Pubmed

NADPH oxidase and the degeneration of dopaminergic neurons in parkinsonian mice.

CYBB NOX1

2.55e-06256224379900
Pubmed

Expression and localization of NOX2 and NOX4 in primary human endothelial cells.

CYBB NOX4

2.55e-06256215706079
Pubmed

Polymorphisms in the promoter regions of RHD and RHCE genes in the Chinese Han population.

RHCE RHD

2.55e-06256237823181
Pubmed

Sequence diversity of the Rh blood group system in Basques.

RHCE RHD

2.55e-06256230089826
Pubmed

ROS-generating oxidases Nox1 and Nox4 contribute to oncogenic Ras-induced premature senescence.

NOX1 NOX4

2.55e-06256223216904
Pubmed

Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation.

NOX1 NOX4

2.55e-06256226222337
Pubmed

Isoforms and functions of NAD(P)H oxidase at the macula densa.

CYBB NOX4

2.55e-06256219204183
Pubmed

Reactive oxygen species generated by NADPH oxidase 2 and 4 are required for chondrogenic differentiation.

CYBB NOX4

2.55e-06256220952384
Pubmed

Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy.

CYBB NOX4

2.55e-06256214551238
Pubmed

Review: the molecular basis of the Rh blood group phenotypes.

RHCE RHD

2.55e-06256215373666
Pubmed

Activation of NADPH oxidases leads to DNA damage in esophageal cells.

CYBB NOX1

2.55e-06256228855537
Pubmed

Structural insights into Nox4 and Nox2: motifs involved in function and cellular localization.

CYBB NOX4

2.55e-06256219995913
Pubmed

The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice.

CYBB NOX1

2.55e-06256216877542
Pubmed

Intron 4 of the RH Gene in Han Chinese, Tibetan, and Mongol Populations.

RHCE RHD

2.55e-06256226579938
Pubmed

NADPH oxidase-1 plays a crucial role in hyperoxia-induced acute lung injury in mice.

CYBB NOX1

2.55e-06256219661248
Pubmed

Redox modifier genes in amyotrophic lateral sclerosis in mice.

CYBB NOX1

2.55e-06256217853944
Pubmed

Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes.

NOX1 NOX4

2.55e-06256222920224
Pubmed

Accurate long-read sequencing allows assembly of the duplicated RHD and RHCE genes harboring variants relevant to blood transfusion.

RHCE RHD

2.55e-06256234968422
Pubmed

Anaerobic Respiration of NOX1-Derived Hydrogen Peroxide Licenses Bacterial Growth at the Colonic Surface.

CYBB NOX1

2.55e-06256233301718
Pubmed

Transfusion strategy for weak D Type 4.0 based on RHD alleles and RH haplotypes in Tunisia.

RHCE RHD

2.55e-06256229193104
Pubmed

Regarding the size of Rh proteins.

RHCE RHD

2.55e-0625621898705
Pubmed

Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis.

CYBB NOX1

2.55e-06256227212019
Pubmed

PCR screening for common weak D types shows different distributions in three Central European populations.

RHCE RHD

2.55e-06256211161244
Pubmed

NADPH oxidase 4 mediates flow-induced superoxide production in thick ascending limbs.

CYBB NOX4

2.55e-06256222896039
Pubmed

Role of Nox4 and Nox2 in hyperoxia-induced reactive oxygen species generation and migration of human lung endothelial cells.

CYBB NOX4

2.55e-06256218783311
Pubmed

RH diversity in Mali: characterization of a new haplotype RHD*DIVa/RHCE*ceTI(D2).

RHCE RHD

2.55e-06256225857637
Pubmed

Hydrogen peroxide derived from NADPH oxidase 4- and 2 contributes to the endothelium-dependent vasodilatation of intrarenal arteries.

CYBB NOX4

2.55e-06256230125808
Pubmed

The low-prevalence Rh antigen STEM (RH49) is encoded by two different RHCE*ce818T alleles that are often in cis to RHD*DOL.

RHCE RHD

2.55e-06256222738288
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

2.55e-06256224990319
Pubmed

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

SCN3A SCN9A

2.55e-06256225172946
Pubmed

Multiple Rh messenger RNA isoforms are produced by alternative splicing.

RHCE RHD

2.55e-0625621379850
Pubmed

Case-control association study of rare nonsynonymous variants of SCN1A and KCNQ2 in acute encephalopathy with biphasic seizures and late reduced diffusion.

SCN1A KCNQ2

2.55e-06256232276107
Pubmed

Characterization of mitochondrial and extra-mitochondrial oxygen consuming reactions in human hematopoietic stem cells. Novel evidence of the occurrence of NAD(P)H oxidase activity.

CYBB NOX4

2.55e-06256215883163
Pubmed

Endothelial NADPH oxidases: which NOX to target in vascular disease?

CYBB NOX1

2.55e-06256225066192
Pubmed

Ethanol induces oxidative stress in alveolar macrophages via upregulation of NADPH oxidases.

CYBB NOX1

2.55e-06256222412195
Pubmed

RHCE variants inherited with altered RHD alleles in Brazilian blood donors.

RHCE RHD

2.55e-06256227111588
Pubmed

Characterization of the mouse Rh blood group gene.

RHCE RHD

2.55e-06256210329015
Pubmed

Alteration of RH gene structure and expression in human dCCee and DCW-red blood cells: phenotypic homozygosity versus genotypic heterozygosity.

RHCE RHD

2.55e-0625628822955
Pubmed

P2X7 receptor activation induces inflammatory responses in salivary gland epithelium.

CYBB P2RX7

2.55e-06256222875784
Pubmed

Angiotensin II stimulates superoxide production in the thick ascending limb by activating NOX4.

CYBB NOX4

2.55e-06256222875785
Pubmed

Differential Roles of the NADPH-Oxidase 1 and 2 in Platelet Activation and Thrombosis.

CYBB NOX1

2.55e-06256226988594
Pubmed

Expression and clinical significance of non-phagocytic cell oxidase 2 and 4 after human traumatic brain injury.

CYBB NOX4

2.55e-06256225079350
InteractionSCN11A interactions

NALCN SCN1A SCN8A SCN9A

5.69e-0815534int:SCN11A
InteractionCACNA1B interactions

NALCN SCN1A SCN9A SPPL3

2.64e-0637534int:CACNA1B
InteractionNALCN interactions

NALCN SCN1A SCN9A

6.12e-0614533int:NALCN
InteractionSCN5A interactions

NALCN SCN1A SCN8A SCN9A

6.99e-0647534int:SCN5A
InteractionSCN9A interactions

NALCN SCN1A SCN9A

2.21e-0521533int:SCN9A
InteractionYIPF4 interactions

ZDHHC15 TLCD4 TMEM63B FKBP7

3.06e-0568534int:YIPF4
InteractionCACNA1D interactions

NALCN SCN1A SCN9A

3.34e-0524533int:CACNA1D
InteractionUPK1A interactions

MBOAT7 TLCD4 SLC49A4 ALG8 ATP11C

4.60e-05150535int:UPK1A
InteractionSCN1A interactions

NALCN SCN1A SCN9A

5.98e-0529533int:SCN1A
InteractionGPR21 interactions

MBOAT7 TLCD4 TMEM63B ATP11C

6.10e-0581534int:GPR21
InteractionCRELD1 interactions

MBOAT7 TLCD4 SCN9A SPPL3 ALG8

6.83e-05163535int:CRELD1
InteractionGPR52 interactions

MBOAT7 TLCD4 ALG8

1.06e-0435533int:GPR52
InteractionTPRA1 interactions

MBOAT7 SPPL3 TMEM63B

1.15e-0436533int:TPRA1
InteractionYIPF3 interactions

ABCC1 TLCD4 SPPL3 TMEM63B ALG8

1.27e-04186535int:YIPF3
InteractionADCYAP1R1 interactions

ZDHHC15 ADCYAP1R1

1.41e-047532int:ADCYAP1R1
InteractionSLC22A4 interactions

MBOAT7 TLCD4 SLC49A4 SPPL3 ALG8

1.48e-04192535int:SLC22A4
InteractionSCN4B interactions

SCN1A SCN8A

1.88e-048532int:SCN4B
InteractionTMEM120B interactions

ENTPD7 ZDHHC15 TLCD4 FKBP7

2.22e-04113534int:TMEM120B
InteractionLMBRD1 interactions

MBOAT7 LMBRD1

2.41e-049532int:LMBRD1
InteractionSCN3B interactions

ENTPD7 GPR61 TMEM63B ALG8 RHD

2.44e-04214535int:SCN3B
InteractionSLC22A9 interactions

MBOAT7 TLCD4 SPPL3 ALG8

2.79e-04120534int:SLC22A9
InteractionNKG7 interactions

TLCD4 MFSD6 FKBP7

3.27e-0451533int:NKG7
InteractionKDELR3 interactions

MBOAT7 TLCD4 ALG8

3.27e-0451533int:KDELR3
CytobandEnsembl 112 genes in cytogenetic band chr2q24

PLA2R1 SCN1A SCN3A SCN9A

1.83e-05127564chr2q24
Cytoband2q24

SCN3A SCN9A

7.98e-05115622q24
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN3A SCN8A SCN9A

2.57e-0994041203
GeneFamilyTLC domain containing

TRAM1L1 TRAM1 TLCD4

1.19e-06104031374
GeneFamilyMembrane bound O-acyltransferases

MBOAT7 MBOAT2

9.95e-0574021036
GeneFamilyProgestin and adipoQ receptor family

PAQR9 PAQR8

2.59e-0411402930
GeneFamilyATPase phospholipid transporting

ATP11C ATP8B1

4.92e-04154021210
GeneFamilyGlycosyltransferase family 6|Blood group antigens

RHCE RHD

3.03e-0337402454
GeneFamilyG protein-coupled receptors, Class A orphans

GPR61 MRGPRE

1.29e-0278402262
CoexpressionAtlasPP_RBC_top-relative-expression-ranked_1000_k-means-cluster#4

CYBB PAQR9 CENPP TLCD4 ATP1B2 MBOAT2 RHCE RHD

9.23e-06422538PP_RBC_1000_K4
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder urothelium (LCM)_emap-30380_k-means-cluster#5_top-relative-expression-ranked_500

PLA2R1 TLCD4 ADGRF4 ATP8B1 ADTRP

1.87e-05131535gudmap_developingLowerUrinaryTract_P2_bladder urothelium (LCM)_500_k5
CoexpressionAtlasStem Cells, SC.MEP.BM, Lineage- Kit+ Sca1- CD34- FcgR-/low, Bone marrow, avg-2

TLCD4 ATP1B2 MBOAT2 RHD

7.22e-0589534GSM791108_100
CoexpressionAtlaskidney_adult_RenCorpuscGlomer_top-relative-expression-ranked_500

CYBB PLA2R1 MFSD6 UGT2B15 ATP8B1 ATP1B2 LMBRD1

1.03e-04438537gudmap_kidney_adult_RenCorpuscGlomer_500
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#3_top-relative-expression-ranked_500

TLCD4 ADGRF4 ATP8B1 ADTRP

1.09e-0499534gudmap_developingLowerUrinaryTract_P1_bladder_J_500_k3
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500

TRANK1 ATP1B2 MBOAT2

1.36e-0440533gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k2_500
CoexpressionAtlasdev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_1000

TRAM1L1 NALCN SCN3A MFSD6 SCN9A

1.47e-04202535gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k3_1000
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_1000

TRAM1L1 NALCN SCN3A SCN9A ADCYAP1R1

1.80e-04211535gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_1000
CoexpressionAtlasPP_RBC_top-relative-expression-ranked_500_k-means-cluster#2

CYBB PAQR9 TLCD4 RHCE RHD

2.01e-04216535PP_RBC_500_K2
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#3_top-relative-expression-ranked_1000

TLCD4 ADGRF4 ATP8B1 ADTRP

2.44e-04122534gudmap_developingLowerUrinaryTract_P1_bladder_B_1000_k3
ToppCellsevere_influenza-RBC|World / disease group, cell group and cell class (v2)

PAQR9 TLCD4 TMEM63B ATP1B2 MBOAT2 RHCE RHD

3.74e-09187567f846750575f318503d21ade30f5bfd2e1d4c84af
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-erythrocytic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PAQR9 TLCD4 ATP1B2 MBOAT2 RHCE RHD

6.89e-08168566360cd756067c8cfb6a78301674758eb5fac52c23
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PAQR9 TLCD4 ATP1B2 MBOAT2 RHCE RHD

6.89e-08168566d791116040a9d3ea0485d68c974340116073986b
ToppCellHealthy-RBC|Healthy / disease group, cell group and cell class

PAQR9 TLCD4 TMEM63B ATP1B2 MBOAT2 RHCE

9.39e-08177566945d72ab52efa9a9468daace9f9ec676a891d963
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR9 CENPP TLCD4 ATP1B2 MBOAT2 RHD

1.26e-07186566ac6e32cf07f0f013101ca7aedae0c562857f182b
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR9 CENPP TLCD4 ATP1B2 MBOAT2 RHD

1.26e-071865667cdcf507a9a1349ed2cf62b79116367c3fc732dd
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR9 CENPP TLCD4 ATP1B2 MBOAT2 RHD

1.30e-07187566dceca7ae3dae96078cccc17a0d8a61b06fa6dffb
ToppCellsevere_COVID-19-RBC|World / disease group, cell group and cell class (v2)

PAQR9 TLCD4 TMEM63B MBOAT2 RHCE RHD

1.52e-071925661b4e28fd2e3d70ab48dbe96b280d35395889fbe2
ToppCellHealthy-RBC|World / disease group, cell group and cell class

PAQR9 TLCD4 TMEM63B ATP1B2 MBOAT2

2.89e-061775652ce41e37fa7139c7bd2b464bd86c5601dc501515
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PAQR9 TLCD4 MBOAT2 RHCE RHD

3.05e-06179565dfefa4b7ae0ee50cf67e0f1938c682f08a03ec53
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-hematologic-erythrocytic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PAQR9 TLCD4 MBOAT2 RHCE RHD

3.05e-0617956564672528f73ac0921f9c7df72e14ecbfac4d5270
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-hematologic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PAQR9 TLCD4 MBOAT2 RHCE RHD

3.05e-06179565fa0dd87111d399649cdea55f2e610ebc169e8a56
ToppCellHSPCs-Erythroblasts|World / Lineage and Cell class

PAQR9 TLCD4 ATP1B2 MBOAT2 RHD

3.22e-06181565ce26f1accc8f69b7bc4b929073e975c887566c6a
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PAQR9 TLCD4 ATP1B2 RHCE RHD

3.40e-06183565b52d7683dc6652766e814ebe935c264ecd610c4b
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PAQR9 TLCD4 ATP1B2 RHCE RHD

3.40e-061835651d77d8d8c8f78f43dd8864e76f294ee66d4942c2
ToppCellCOVID-19_Severe-RBC|COVID-19_Severe / disease group, cell group and cell class

PAQR9 TLCD4 TMEM63B ATP1B2 RHCE

3.49e-06184565bb58244194ffb5558fbe85c5f856888210dcb1e8
ToppCellCOVID-19_Severe-RBC|World / disease group, cell group and cell class

PAQR9 TLCD4 TMEM63B RHCE RHD

3.59e-0618556596b7058b1b282134970aa9e75285760a9f94a8b5
ToppCellAnterior_Cingulate_gyrus_(CgG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN9A ADTRP ATP1B2 MBOAT2 ADCYAP1R1

3.68e-0618656532af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 TMEM121B SCN1A SCN8A KCNQ2

3.68e-061865657278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PAQR9 TLCD4 UGT2B15 RHCE RHD

3.78e-06187565edb0ab0154542b1c0b3a2c216c4a60f0f06290b3
ToppCellInfluenza_Severe-RBC|World / Disease group and Cell class

PAQR9 TLCD4 MBOAT2 RHCE RHD

3.88e-06188565f0438e6a77ee1f0456cb65926685266fff470983
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PAQR9 TLCD4 UGT2B15 RHCE RHD

3.98e-061895657899af78b273d9c7f029d52f7e0cf6df4da41f5e
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PAQR9 TLCD4 UGT2B15 RHCE RHD

4.09e-06190565a34293601aefe5fb5c400c14091294b9ddaa195b
ToppCellsevere_COVID-19-RBC|severe_COVID-19 / disease group, cell group and cell class (v2)

PAQR9 TLCD4 TMEM63B RHCE RHD

4.09e-061905653a5723c2daf58c1932edd70910db4b8b30f63f42
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPP TLCD4 ATP1B2 MBOAT2 RHD

4.30e-06192565a94f47a664a3c9d1b0250269674453309ab4bf95
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 TMEM121B SCN1A SCN8A KCNQ2

4.41e-06193565be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 TMEM121B SCN1A SCN8A KCNQ2

4.41e-061935650c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 TMEM121B SCN1A SCN8A KCNQ2

4.41e-061935658689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast|World / Lineage, cell class and subclass

TLCD4 ATP1B2 MBOAT2 RHCE RHD

4.52e-06194565008bb0072f414a48d052429101bdc990ee4f80c2
ToppCell15-Trachea-RBC-RBC|Trachea / Age, Tissue, Lineage and Cell class

PAQR9 TLCD4 ATP1B2 RHCE RHD

4.75e-06196565511bfc06c34d5add2ae561cca463d1e4e2d43e20
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-hematologic-hematopoietic_progenitor-erythroid_progenitor_cell|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPGS2 ATP1B2 MBOAT2 RHCE RHD

4.75e-06196565c391d6359634145455c71c7f051bf34ff0eb666d
ToppCell15-Trachea-RBC|Trachea / Age, Tissue, Lineage and Cell class

PAQR9 TLCD4 ATP1B2 RHCE RHD

4.75e-06196565bf2670e5ae996a19987bc70aa5a37d133db789eb
ToppCellerythropoietic-Erythrocyte|World / Lineage and Cell class

TLCD4 TPGS2 MBOAT2 RHCE RHD

4.75e-061965651642d9340f621cd55987ef8154b48aa306f0f0c8
ToppCell21-Trachea-RBC|Trachea / Age, Tissue, Lineage and Cell class

TLCD4 ATP1B2 MBOAT2 RHCE RHD

4.87e-061975659f8eb6305ade0654bbcd8f19963be0b64af083de
ToppCellerythropoietic-Polychromatic_Erythroblast|World / Lineage and Cell class

TLCD4 ATP1B2 MBOAT2 RHCE RHD

4.87e-06197565604fcbf47f073c2af344e1b16b615a78ef838dc9
ToppCell21-Trachea-RBC-RBC|Trachea / Age, Tissue, Lineage and Cell class

TLCD4 ATP1B2 MBOAT2 RHCE RHD

4.87e-061975654710b55806a618076a954190f519e49c55d300d3
ToppCellCOVID-19-COVID-19_Severe-Others-RBC|COVID-19_Severe / Disease, condition lineage and cell class

TLCD4 TMEM63B MBOAT2 RHCE RHD

5.25e-06200565308f74e7e13ecc6d133c219c42cc8895a96644c8
ToppCellBronchial-10x5prime-Hematologic-Erythrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TLCD4 ATP1B2 RHCE RHD

1.92e-0512656465c7c0e4cfb5ac58d80b4034d42e9f662116e0d3
ToppCellBronchial-10x5prime-Hematologic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TLCD4 ATP1B2 RHCE RHD

1.92e-05126564b6482ef18e6d9e12ba4810ce7845f9f991cb95bc
ToppCellBronchial-10x5prime-Hematologic-Erythrocyte-Erythrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TLCD4 ATP1B2 RHCE RHD

1.92e-0512656412f3d0f60db462f2a9799b3a06005bc871670760
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 SCN8A SCN9A NOX4

2.67e-051375644dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 SCN8A SCN9A NOX4

2.67e-05137564c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR8 ATP1B2 MBOAT2 RHD

4.90e-051605649f24ee4fe1ba4590dce5dd4d43707fb007dca82f
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR8 ATP1B2 MBOAT2 RHD

4.90e-051605643b3b99305558f5b49d050fb9b249007630ea9085
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NOX1 TRAM1L1 MRGPRE FKBP7

6.06e-05169564f086b50791e1c93e253eb5e8d6c4bf617b1416c3
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 NALCN SCN3A SCN9A

6.06e-0516956412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TLCD4 KCNQ2 ADGRF4 MBOAT2

6.94e-05175564f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TLCD4 KCNQ2 ADGRF4 MBOAT2

6.94e-051755647bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCellwk_15-18-Hematologic-Meg-ery-Definitive_erythrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PAQR9 TLCD4 TMEM63B RHCE

7.09e-051765649af82b976e6a14a3ef7aa50f1f7af2463e5aa5d2
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR9 CENPP ATP1B2 RHD

7.57e-05179564804aa3899585fc7e662eff9f6d41f48655f16dd6
ToppCellMultiple_Sclerosis-Other-RBC|Multiple_Sclerosis / Disease, Lineage and Cell Type

PAQR9 TMEM63B RHCE RHD

7.57e-0517956415763dc59ee6186416e203ffbb450ae4608eba59
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP11C ATP1B2 OPN1SW ADCYAP1R1

7.90e-0518156403a303cd2f366f09c18b118bbba6f5e3f95ad56c
ToppCellHSPCs-Erythroblasts|HSPCs / Lineage and Cell class

PAQR9 TLCD4 MBOAT2 RHD

7.90e-051815644ded490f190af7ace343acdf317edc7373484d08
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPP SCN3A ATP1B2 NPFFR1

8.07e-05182564c84f44391932080df31c8765e363c3dff64b2bd1
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PAQR9 TLCD4 RHCE RHD

8.25e-051835641db466cf757813322db1cdcc0bf1d91c062fd9de
ToppCellwk_15-18-Hematologic-Meg-ery-Definitive_reticulocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PAQR9 TLCD4 TMEM63B RHCE

8.25e-051835645470e5ac3439cfc96acd2202f6b1e386779a6637
ToppCellPBMC-Severe-Hematopoietic-RBC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PAQR9 TLCD4 RHCE RHD

8.60e-05185564d685a5a2e525db2eba449cfa1e5cd54eb36162a8
ToppCellPBMC-Severe-Hematopoietic-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PAQR9 TLCD4 RHCE RHD

8.60e-051855645d8d6fd7800f76ee3aa5cef95241d8e6d7e8db04
ToppCellPBMC-Severe-Hematopoietic-RBC-RBC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PAQR9 TLCD4 RHCE RHD

8.60e-05185564100b5afdf3c6ab07ffc493f7883f5a7b31c59184
ToppCellCOVID-19_Severe-Hematopoietic_R|COVID-19_Severe / Disease group, lineage and cell class

PAQR9 TLCD4 RHCE RHD

8.60e-0518556430f064ab7c3890e6f419a845276b145112e78f52
ToppCelldroplet-Marrow-nan-18m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR9 TLCD4 ATP1B2 RHD

8.60e-05185564a45756f91b62cf0fac3582786e5868deb8fd8435
ToppCellPBMC-Severe-Hematopoietic-RBC-RBC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PAQR9 TLCD4 RHCE RHD

8.60e-05185564f3b1907c3b6f930bc161f46efce5e143babab507
ToppCellPBMC-Severe-Hematopoietic-RBC-RBC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PAQR9 TLCD4 RHCE RHD

8.60e-0518556444ce50cb99df8ffc50eba311adcf688477618659
ToppCellCOVID-cycling-|COVID / Condition, Cell_class and T cell subcluster

CENPP PLA2R1 ATP1B2 RHCE

8.60e-05185564eb74b8d36f7b749e04bc2ed4b36f7e1ac7bb6d5f
ToppCell10x5'v1-week_17-19-Hematopoietic-erythroid-mid_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TLCD4 TMEM63B ATP1B2 RHCE

8.60e-05185564e9059cefcdf0972ec90793b1dd34c3292b17a061
ToppCellPBMC-Severe-Hematopoietic-RBC-RBC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PAQR9 TLCD4 RHCE RHD

8.60e-0518556417542ccd52a821c9e99b1a7469e80502e764b3fd
ToppCellCOVID-19_Severe-Hematopoietic_R-RBC|COVID-19_Severe / Disease group, lineage and cell class

PAQR9 TLCD4 RHCE RHD

8.60e-051855643ed6090b822c6d1d400a421236cddc7511743932
ToppCellCOVID-cycling|COVID / Condition, Cell_class and T cell subcluster

CENPP PLA2R1 ATP1B2 RHCE

8.60e-051855645112f966735fa48f0606adcfd5c0212ad5d3d77a
ToppCellCerebellum-Neuronal|Cerebellum / BrainAtlas - Mouse McCarroll V32

TRANK1 GPR61 NALCN SCN1A

8.96e-0518756461b9d6eb131a674598aa8409d7fa909c8765442d
ToppCelldroplet-Spleen-nan-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD4 ATP1B2 MBOAT2 RHD

8.96e-05187564c81d11d9fdc22dc39222f62c2888025c2e8c3e65
ToppCell10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega-Erythrocytic_early|lymph-node_spleen / Manually curated celltypes from each tissue

PAQR9 TLCD4 MBOAT2 RHCE

8.96e-0518756461d346c9873c2edb3ce224a0c063c54d9a68309e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCN3A ATP8B1 ADTRP MBOAT2

8.96e-051875642d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Red_blood_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAQR9 TLCD4 TMEM63B RHCE

9.15e-05188564f81099b5b3f1f85a28445bc663efcf73baccb2be
ToppCelldroplet-Marrow-BM-30m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR9 TLCD4 MBOAT2 RHD

9.15e-05188564f1a9d8ea174a4bef0fae8188e3bd96b7ac1a39bb
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TRANK1 SCN3A SCN9A KCNQ2

9.15e-05188564b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Red_blood_cells-RBC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAQR9 TLCD4 TMEM63B RHCE

9.15e-0518856405b3ade422beeb3db73d350fe192c21bfcfef188
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD4 ATP1B2 MBOAT2 RHD

9.34e-0518956416dfc37d8d390ed7f927bc844c47c9c5a89a0928
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 TMEM121B SCN3A KCNQ2

9.34e-051895643e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD4 ATP1B2 MBOAT2 RHD

9.34e-051895643ade3fa9369e85304b20d7233b581f18ad5ecc89
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|World / Lineage, cell class and subclass

TLCD4 MBOAT2 RHCE RHD

9.34e-05189564826457adac7477102f86aceb97a8b77929b3e6f9
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 TMEM121B SCN3A KCNQ2

9.34e-05189564851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCellNeuroendocrine-neuroendo-2-Calca|World / Class top

SCN3A SCN8A SCN9A MBOAT2

9.34e-051895646baa9a74560121cc008bb8fa9b2b7a335b3aeee0
ToppCelldroplet-Spleen-nan-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD4 ATP1B2 MBOAT2 RHD

9.53e-05190564a273fc119baebc11020009c923beafeebb6428c9
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 TMEM121B SCN3A KCNQ2

9.53e-051905641c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PAQR9 GPR61 SCN8A KCNQ2

9.53e-05190564416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellMegakaryocytic-erythropoietic-Erythro-cells|World / Lineage, cell class and subclass

TLCD4 MBOAT2 RHCE RHD

9.53e-051905646c7e016a9b425ee9418acd4fe96b9779fe7bd39a
ToppCelldroplet-Marrow-BM-1m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR9 TLCD4 MBOAT2 RHD

9.73e-05191564d78d4fbb0b8317dbf14e32182466a432abef3e93
ToppCell10x3'2.3-week_12-13-Hematopoietic-erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TLCD4 ATP1B2 MBOAT2 RHCE

9.92e-051925646ace9a34ed264583042156ed61c2cb3504a331d2
ToppCellInfluenza_Severe-RBC|Influenza_Severe / Disease group and Cell class

TLCD4 MBOAT2 RHCE RHD

9.92e-05192564f19b6da3fd98da1a76d2570137a8f73a3850ebcb
ToppCell10x3'2.3-week_12-13-Hematopoietic-erythroid-mid_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TLCD4 TMEM63B ATP1B2 RHCE

1.01e-041935641e19f80c52833fb21a8d597a3ba2c4ff464c4559
ToppCellMegakaryocytic-erythropoietic|World / Lineage, cell class and subclass

TLCD4 MBOAT2 RHCE RHD

1.01e-04193564805c2e2e5d8a9df5ce796d5c0206d6493ab53c88
ToppCellsevere_influenza-RBC|severe_influenza / disease group, cell group and cell class (v2)

TLCD4 MBOAT2 RHCE RHD

1.01e-04193564ffb0b3c2cce13b6891157f0fede2600f3938670e
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

TLCD4 TMEM63B RHCE RHD

1.03e-04194564f0ababe8daa57f6827a3e2e72c884d9e8b2687a3
ToppCell10x3'2.3-week_14-16-Hematopoietic-erythroid-mid_erythroid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TLCD4 TMEM63B ATP1B2 RHCE

1.05e-041955644759018a7c016cb2e3df5696f1e5f912c7c9ee17
ToppCell10x3'2.3-week_14-16-Hematopoietic-erythroid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TLCD4 ATP1B2 MBOAT2 RHCE

1.05e-04195564b24f6fe71fbcffe7ff1fd1374455c378837d6313
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TLCD4 TMEM63B ATP1B2 RHCE

1.07e-041965640aae78e73d53416d857bdf21f595a0a0a0ba7944
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid-mid_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TLCD4 TMEM63B ATP1B2 RHCE

1.10e-04197564d8f99a9f2367c8bc9308b0c64d0226875262927a
ToppCellerythropoietic|World / Lineage and Cell class

TLCD4 TPGS2 MBOAT2 RHCE

1.10e-04197564a52546cebc222050c970e04cec97e4f48ab8fe10
ToppCell10x3'2.3-week_14-16-Hematopoietic|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TLCD4 ATP1B2 MBOAT2 RHCE

1.10e-0419756497a837477043902f0f5c9db850a3bfa001ea74d1
ToppCell10x5'v1-week_12-13-Hematopoietic|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TLCD4 TMEM63B ATP1B2 RHCE

1.12e-04198564d02e1ff7f68dedaca1e367c7cade772e7b355f45
ComputationalPorins / transporters.

CYBB PLA2R1 P2RX7 SCN9A ADCYAP1R1

2.65e-04211305MODULE_63
Drugindoxacarb

SCN3A SCN9A ATP8B1 RHCE RHD

1.32e-0749565CID000107720
Drugpheophytin

ABCC1 NOX1 GALNS UGT2B15 NOX4 ATP8B1 RHCE RHD

4.49e-07284568CID000000250
Drug1, 3-diallylurea

ABCC1 SCN3A SCN9A RHCE RHD

1.06e-0674565CID000074537
Drugdiphenyline

CYBB NOX1 NOX4

1.67e-0610563CID000010292
DrugTetrodotoxin

CYBB SCN3A SCN8A SCN9A

2.81e-0640564ctd:D013779
Drugdihydroethidium

CYBB NOX1 P2RX7 NOX4 NOX3

3.67e-0695565CID000128682
DrugSuperoxides

CYBB ABCC1 NOX1 NOX4 NOX3

6.00e-06105565ctd:D013481
Drugdalcetrapib

CYBB NOX1 NOX4

6.28e-0615563ctd:C411602
DrugZonisamide

SCN1A SCN3A SCN9A

9.35e-0617563DB00909
Druganacetrapib

CYBB NOX1 NOX4

1.33e-0519563ctd:C530884
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN3A SCN9A

1.78e-053562ctd:C561228
DrugDCFH-DA

CYBB NOX1 P2RX7 NOX4

6.00e-0586564CID000104913
DrugMequindox

CYBB NOX1 NOX4

6.65e-0532563ctd:C545385
Drugbiphenylene

CYBB NOX1 NOX4

7.99e-0534563CID000009214
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

ENGASE PPP4R3B NOX1 MBOAT7 MFSD6

8.05e-051805655203_UP
DrugCGP 42112A

NOX1 NOX4

8.86e-056562ctd:C060894
DrugAPETx1, Anthopleura elegantissima

SCN3A SCN8A

8.86e-056562ctd:C475726
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN3A SCN8A SCN9A

2.42e-0910564DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN3A SCN8A SCN9A

2.42e-0910564DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN3A SCN8A SCN9A

5.69e-0912564DOID:0060170 (implicated_via_orthology)
DiseaseAnemia, Hemolytic, Congenital

RHCE RHD

3.54e-062562C0002881
DiseaseEarly Infantile Epileptic Encephalopathy 6

SCN1A SCN9A

3.54e-062562C4551549
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN3A SCN9A

9.72e-0622563DOID:2030 (implicated_via_orthology)
DiseaseB Virus Infection

SCN8A SCN9A

1.06e-053562C0037140
DiseasePostherpetic neuralgia

SCN8A SCN9A

1.06e-053562C0032768
DiseaseRh Deficiency Syndrome

RHCE RHD

1.06e-053562C0272052
DiseaseHerpesviridae Infections

SCN8A SCN9A

1.06e-053562C0019372
DiseaseRh-Null, Regulator Type

RHCE RHD

1.06e-053562C1849387
Diseaseepilepsy (implicated_via_orthology)

SCN1A SCN3A SCN8A SCN9A ATP1B2

1.47e-05163565DOID:1826 (implicated_via_orthology)
Disease1-oleoyl-GPI (18:1) measurement

PAQR9 MBOAT7

2.12e-054562EFO_0800265
DiseaseFamilial benign neonatal epilepsy

SCN8A KCNQ2

5.28e-056562C0220669
DiseaseEpilepsy

SCN1A SCN8A SCN9A KCNQ2

5.58e-05109564C0014544
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A SCN9A

9.83e-058562C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A SCN9A

9.83e-058562C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A SCN9A

9.83e-058562C0338479
DiseaseMyoclonic Encephalopathy

SCN1A SCN9A

9.83e-058562C0438414
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A SCN9A

9.83e-058562C0751120
DiseaseMyoclonic Absence Epilepsy

SCN1A SCN9A

9.83e-058562C0393703
DiseaseMyoclonic Epilepsy

SCN1A SCN9A

1.26e-049562C0014550
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN9A

1.26e-049562C3502809
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A SCN9A

1.58e-0410562C0917800
Disease1-stearoyl-2-oleoyl-GPI (18:0/18:1) measurement

PAQR9 MBOAT7

1.58e-0410562EFO_0800469
DiseaseMyoclonic Astatic Epilepsy

SCN1A SCN9A

1.92e-0411562C0393702
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN9A

2.72e-0413562C0751122
Diseasephosphatidate measurement

PAQR9 MBOAT7

3.66e-0415562EFO_0020047
DiseaseEpilepsy, Cryptogenic

SCN1A SCN8A KCNQ2

5.16e-0482563C0086237
DiseaseAwakening Epilepsy

SCN1A SCN8A KCNQ2

5.16e-0482563C0751111
DiseaseAura

SCN1A SCN8A KCNQ2

5.16e-0482563C0236018
Diseaseethylmalonate measurement

P2RX7 SPPL3

6.58e-0420562EFO_0020009
DiseaseNeurodevelopmental Disorders

SCN1A SCN8A KCNQ2

7.44e-0493563C1535926
Diseaseobsolete_red blood cell distribution width

PAQR9 ABCC1 TMEM63B UGT2B15 ATP11C SLC25A26 ATP1B2 RHCE RHD

9.15e-041347569EFO_0005192
DiseaseHDL cholesterol change measurement

MBOAT2 ABCA10

9.51e-0424562EFO_0007805
DiseaseMyocardial Failure

CYBB NOX1 NOX4

1.21e-03110563C1959583
DiseaseCongestive heart failure

CYBB NOX1 NOX4

1.21e-03110563C0018802
DiseaseHeart failure

CYBB NOX1 NOX4

1.21e-03110563C0018801
DiseaseLeft-Sided Heart Failure

CYBB NOX1 NOX4

1.21e-03110563C0023212
DiseaseHeart Failure, Right-Sided

CYBB NOX1 NOX4

1.21e-03110563C0235527
DiseaseHeart Decompensation

CYBB NOX1 NOX4

1.21e-03110563C1961112
DiseaseHbA1c measurement

PAQR9 ABCC1 GALNS TRAM1L1 ATP1B2 RHCE

1.72e-03675566EFO_0004541

Protein segments in the cluster

PeptideGeneStartEntry
DLIHSFLYIYYVHWS

AKAP14

106

Q86UN6
HLIYYFIFLGFQLSW

ABCA10

996

Q8WWZ4
VTFFSHFFYLSLFFW

ADGRF4

476

Q8IZF3
TCIYHFLVLSWYTFL

ADTRP

6

Q96IZ2
FFRSLHFFVEWFEYR

CENPP

166

Q6IPU0
YKNFAFTLVHFWYSF

ATP8B1

956

O43520
VTVYAFPFAHWLAFF

NPFFR1

306

Q9GZQ6
FEVFWYTHHLFIFYI

NOX1

201

Q9Y5S8
FLLCWLPYFSFHLYV

GPR61

296

Q9BZJ8
YLALFCFGWYALHFL

MBOAT2

66

Q6ZWT7
SWFRLSFVYNHYLFF

ENTPD7

541

Q9NQZ7
YLFLHKFWFFSAAYY

LMBRD1

481

Q9NUN5
SWAFILLFYLVFYGF

ATP1B2

36

P14415
WAFIYHAYVFLLVFS

KCNQ2

91

O43526
FYLLAFFFIFYSQIW

OR52A4P

256

A6NMU1
DTLRYWASIYFCIHF

MBOAT7

421

Q96N66
FFLKHYRYSWSFICT

PPP4R3B

491

Q5MIZ7
YGFVFTFLYWHLEDL

MFSD6

461

Q6ZSS7
NLLWYIPHYFYHFSF

MRGPRE

241

Q86SM8
NYDIFWYTHNLFFVF

NOX4

186

Q9NPH5
VFFHYCVVSNYFWLF

ADCYAP1R1

231

P41586
HFYRRYFWLVVAAFF

PAQR9

276

Q6ZVX9
WYHTLQILFFLVSAY

PAQR8

246

Q8TEZ7
YGTIKWFFHVIIFSY

P2RX7

26

Q99572
WFFHVIIFSYVCFAL

P2RX7

31

Q99572
FFLYWAVDATHAPVY

GALNS

226

P34059
HFLFRFIVFFYLWGL

FKBP7

6

Q9Y680
LLFFLTFYHTELSWF

SLC49A4

431

Q96SL1
LPTIVYYSAFFEAHW

TMEM63B

491

Q5T3F8
ATFFVHFFYLSVFFW

ADGRF2

521

Q8IZF7
YFEVFWYTHHLFVIF

CYBB

201

P04839
FIFHSWILLFHFYFT

CXorf1

61

O96002
AFYHWQCIDVFVYFS

ENGASE

151

Q8NFI3
AFFITYEYVKWFLHA

SLC25A26

66

Q70HW3
YHIAPVWAFYLQAAF

OPN1SW

26

P03999
LWACFPFYFLYLSRH

ABCC1

46

P33527
FAFAYLAWLIYSIAF

TMEM121B

311

Q9BXQ6
HYYFTVGWNIFDFVV

SCN9A

1571

Q15858
RHYYFTIGWNIFDFV

SCN3A

1581

Q9NY46
ELFWYTHHVFIVFFL

NOX3

201

Q9HBY0
WLFYQDAEYLFHTFA

PLA2R1

816

Q13018
RHYYFTIGWNIFDFV

SCN1A

1596

P35498
FAWFEYILSHVAKYF

ALG8

71

Q9BVK2
HFVIWGSLAFYVFFS

ATP11C

1026

Q8NB49
KFFYISQLAYWFHAF

TRAM1L1

166

Q8N609
SQLAYWFHAFPELYF

TRAM1L1

171

Q8N609
HIYVFAAYFGLSVAW

RHD

171

Q02161
HFYVFAAYFGLTVAW

RHCE

171

P18577
LLIYDVFWVFFSAYI

SPPL3

196

Q8TCT6
SFFVFYSVHSFLTIW

VN1R1

281

Q9GZP7
LLFYFVSYWFSAKVS

TLCD4

21

Q96MV1
LRHYYFTIGWNIFDF

SCN8A

1576

Q9UQD0
FANCSVYDFFVWLHY

DCT

176

P40126
YWHFLTDTFTAYYRL

TPGS2

181

Q68CL5
KFFYISQLAYWLHAF

TRAM1

166

Q15629
IHMLYFDFWFQIYDL

UGT2B15

216

P54855
SLVLFYKAYHFWVFV

XKR5

196

Q6UX68
KSYIALLHYWEFLFS

TRANK1

2436

O15050
IYLILYHAIFVFFTW

ZDHHC15

56

Q96MV8
WRSYFYFITLIFFLA

NALCN

296

Q8IZF0