Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.12e-07	279	97	11	GO:0005096
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA2D1 SLC5A9 SLC39A4 GRIN2D ORAI2 SLC5A3 SLC30A7 SLC12A9 SLC28A2 SLC38A7 ATP1A2 SLC41A1 ATP1A4	3.95e-07	465	97	13	GO:0046873
GeneOntologyMolecularFunction	hexose transmembrane transporter activity	SLC2A8 SLC5A9 SLC2A2 SLC5A3	6.12e-06	25	97	4	GO:0015149
GeneOntologyMolecularFunction	D-glucose transmembrane transporter activity	SLC2A8 SLC5A9 SLC2A2 SLC5A3	6.12e-06	25	97	4	GO:0055056
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	CACNA2D1 TMC6 GABRQ SLC5A9 SLC39A4 GRIN2D ORAI2 SLC5A3 SLC30A7 SLC12A9 SLC28A2 SLC38A7 ATP1A2 SLC41A1 ATP1A4	6.29e-06	793	97	15	GO:0015075
GeneOntologyMolecularFunction	monosaccharide transmembrane transporter activity	SLC2A8 SLC5A9 SLC2A2 SLC5A3	8.43e-06	27	97	4	GO:0015145
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA2D1 SLC5A9 SLC39A4 GRIN2D ORAI2 SLC5A3 SLC30A7 SLC12A9 SLC28A2 SLC38A7 ATP1A2 SLC41A1 ATP1A4	1.06e-05	627	97	13	GO:0022890
GeneOntologyMolecularFunction	sugar transmembrane transporter activity	SLC2A8 SLC5A9 SLC2A2 SLC5A3	1.13e-05	29	97	4	GO:0051119
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA2D1 SLC2A8 TMC6 GABRQ SLC5A9 SLC39A4 GRIN2D ORAI2 SLC7A14 SLC2A2 SLC5A3 SLC30A7 SLC12A9 SLC28A2 SLC38A7 ATP1A2 SLC41A1 ATP1A4	1.33e-05	1180	97	18	GO:0022857
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC5A9 SLC39A4 SLC5A3 SLC12A9 SLC28A2 SLC38A7 ATP1A2 SLC41A1 ATP1A4	1.60e-05	301	97	9	GO:0022853
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CACNA2D1 GABRQ SLC5A9 SLC39A4 GRIN2D ORAI2 SLC5A3 SLC30A7 SLC12A9 SLC28A2 SLC38A7 ATP1A2 SLC41A1 ATP1A4	1.73e-05	758	97	14	GO:0015318
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA2D1 SLC5A9 SLC39A4 GRIN2D ORAI2 SLC5A3 SLC30A7 SLC12A9 SLC28A2 SLC38A7 ATP1A2 SLC41A1 ATP1A4	1.94e-05	664	97	13	GO:0008324
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC5A9 SLC5A3 SLC28A2 SLC38A7 ATP1A2 SLC41A1 ATP1A4	2.01e-05	171	97	7	GO:0015081
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC5A9 SLC39A4 SLC5A3 SLC12A9 SLC28A2 SLC38A7	2.51e-05	119	97	6	GO:0015294
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	3.52e-05	507	97	11	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	3.52e-05	507	97	11	GO:0030695
GeneOntologyMolecularFunction	transporter activity	CACNA2D1 SLC2A8 TMC6 GABRQ SLC5A9 SLC39A4 GRIN2D ORAI2 SLC7A14 SLC2A2 SLC5A3 SLC30A7 SLC12A9 SLC28A2 SLC38A7 ATP1A2 SLC41A1 ATP1A4	4.30e-05	1289	97	18	GO:0005215
GeneOntologyMolecularFunction	carbohydrate transmembrane transporter activity	SLC2A8 SLC5A9 SLC2A2 SLC5A3	5.08e-05	42	97	4	GO:0015144
GeneOntologyMolecularFunction	enzyme activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B POLG2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	7.95e-05	656	97	12	GO:0008047
GeneOntologyMolecularFunction	symporter activity	SLC5A9 SLC39A4 SLC5A3 SLC12A9 SLC28A2 SLC38A7	9.15e-05	150	97	6	GO:0015293
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC2A8 SLC5A9 SLC39A4 SLC5A3 SLC12A9 SLC28A2 SLC38A7 SLC41A1	9.79e-05	296	97	8	GO:0015291
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC2A8 SLC5A9 SLC39A4 SLC5A3 SLC12A9 SLC28A2 SLC38A7 ATP1A2 SLC41A1 ATP1A4	1.08e-04	477	97	10	GO:0022804
GeneOntologyMolecularFunction	phosphorylase kinase activity	PHKA1 PHKA2	1.39e-04	4	97	2	GO:0004689
GeneOntologyMolecularFunction	galactose transmembrane transporter activity	SLC2A8 SLC2A2	3.46e-04	6	97	2	GO:0005354
GeneOntologyMolecularFunction	D-glucose:sodium symporter activity	SLC5A9 SLC5A3	4.83e-04	7	97	2	GO:0005412
GeneOntologyMolecularFunction	dehydroascorbic acid transmembrane transporter activity	SLC2A8 SLC2A2	6.42e-04	8	97	2	GO:0033300
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC5A9 SLC5A3 SLC28A2 SLC38A7	6.54e-04	81	97	4	GO:0015370
GeneOntologyMolecularFunction	fructose transmembrane transporter activity	SLC2A8 SLC2A2	8.22e-04	9	97	2	GO:0005353
GeneOntologyMolecularFunction	molecular function activator activity	TBC1D3E RELN TBC1D3 TBC1D3H TBC1D3L TBC1D3D SHH GPHA2 TBC1D3C TBC1D3B POLG2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	8.64e-04	1233	97	15	GO:0140677
GeneOntologyMolecularFunction	P-type sodium transporter activity	ATP1A2 ATP1A4	1.02e-03	10	97	2	GO:0008554
GeneOntologyMolecularFunction	P-type sodium:potassium-exchanging transporter activity	ATP1A2 ATP1A4	1.02e-03	10	97	2	GO:0005391
GeneOntologyMolecularFunction	P-type potassium transmembrane transporter activity	ATP1A2 ATP1A4	1.25e-03	11	97	2	GO:0008556
GeneOntologyMolecularFunction	carbon-carbon lyase activity	PDXDC1 UXS1 DERA	2.56e-03	56	97	3	GO:0016830
GeneOntologyMolecularFunction	cGMP binding	PDE10A PRKG2	2.68e-03	16	97	2	GO:0030553
GeneOntologyMolecularFunction	carbohydrate:monoatomic cation symporter activity	SLC5A9 SLC5A3	3.03e-03	17	97	2	GO:0005402
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC2A8 SLC39A4 GRIN2D SLC7A14 SLC2A2 SLC38A7	3.07e-03	293	97	6	GO:0008514
GeneOntologyMolecularFunction	neurotransmitter transmembrane transporter activity	GABRQ SLC28A2	4.62e-03	21	97	2	GO:0005326
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ATR PIGG STK31 PAPSS1 PKMYT1 PHKA1 PHKA2 OASL ROS1 PRKG2 POLG2	5.78e-03	938	97	11	GO:0016772
GeneOntologyMolecularFunction	zinc ion transmembrane transporter activity	SLC39A4 SLC30A7	6.01e-03	24	97	2	GO:0005385
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	4.09e-12	109	98	11	GO:0090630
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.30e-08	244	98	11	GO:0043547
GeneOntologyBiologicalProcess	regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RDX TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	6.44e-08	335	98	12	GO:0043087
GeneOntologyBiologicalProcess	positive regulation of early endosome to late endosome transport	EZR RDX MSN	8.56e-06	9	98	3	GO:2000643
GeneOntologyBiologicalProcess	regulation of protein localization to early endosome	EZR RDX MSN	1.22e-05	10	98	3	GO:1902965
GeneOntologyBiologicalProcess	positive regulation of protein localization to early endosome	EZR RDX MSN	1.22e-05	10	98	3	GO:1902966
GeneOntologyBiologicalProcess	positive regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.50e-05	499	98	11	GO:0051345
GeneOntologyBiologicalProcess	positive regulation of protein localization to endosome	EZR RDX MSN	3.64e-05	14	98	3	GO:1905668
GeneOntologyBiologicalProcess	regulation of protein localization to endosome	EZR RDX MSN	4.54e-05	15	98	3	GO:1905666
GeneOntologyBiologicalProcess	protein localization to early endosome	EZR RDX MSN	5.57e-05	16	98	3	GO:1902946
GeneOntologyBiologicalProcess	regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RDX TBC1D3C TBC1D3B MGAT5 OASL TBC1D3I TBC1D3G TBC1D3K TBC1D3F	6.78e-05	878	98	14	GO:0051336
GeneOntologyBiologicalProcess	monoatomic ion transport	CACNA2D1 RELN HTR1A TMC6 GABRQ SLC5A9 SLC39A4 GRIN2D ORAI2 SLC5A3 SLC30A7 SLC12A9 SLC38A7 PRKG2 ATP1A2 HEPHL1 SLC41A1 ATP1A4	7.45e-05	1374	98	18	GO:0006811
GeneOntologyBiologicalProcess	positive regulation of catalytic activity	TBC1D3E RELN TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B SLC5A3 ROS1 POLG2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	9.89e-05	1028	98	15	GO:0043085
GeneOntologyBiologicalProcess	regulation of early endosome to late endosome transport	EZR RDX MSN	1.12e-04	20	98	3	GO:2000641
GeneOntologyCellularComponent	T-tubule	EZR CACNA2D1 RDX MSN ATP1A2	3.50e-05	79	98	5	GO:0030315
GeneOntologyCellularComponent	cell tip	EZR RDX MSN	6.48e-05	17	98	3	GO:0051286
GeneOntologyCellularComponent	cell pole	EZR RDX MSN	1.07e-04	20	98	3	GO:0060187
GeneOntologyCellularComponent	phosphorylase kinase complex	PHKA1 PHKA2	2.16e-04	5	98	2	GO:0005964
Domain	TBC_RABGAP	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D32 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	4.10e-15	55	97	11	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D32 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	4.10e-15	55	97	11	IPR000195
Domain	TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	6.17e-14	49	97	10	SM00164
Domain	RabGAP-TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.44e-13	53	97	10	PF00566
Domain	DUF3669_Znf	ZNF777 ZNF783 ZNF398 ZNF282	1.02e-08	6	97	4	IPR022137
Domain	DUF3669	ZNF777 ZNF783 ZNF398 ZNF282	1.02e-08	6	97	4	PF12417
Domain	ERM_C_dom	EZR RDX MSN	5.41e-07	4	97	3	IPR011259
Domain	ERM	EZR RDX MSN	5.41e-07	4	97	3	PF00769
Domain	ERM	EZR RDX MSN	5.41e-07	4	97	3	IPR011174
Domain	Moesin_tail	EZR RDX MSN	4.68e-06	7	97	3	IPR008954
Domain	Glyco_hydro_15	PHKA1 PHKA2	7.98e-05	3	97	2	PF00723
Domain	Glyco_hydro_15/PHK	PHKA1 PHKA2	7.98e-05	3	97	2	IPR011613
Domain	PHK_A/B_su	PHKA1 PHKA2	7.98e-05	3	97	2	IPR008734
Domain	Ez/rad/moesin-like	EZR RDX MSN	1.69e-04	21	97	3	IPR000798
Domain	FERM_CS	EZR RDX MSN	2.54e-04	24	97	3	IPR019747
Domain	FERM_C	EZR RDX MSN	3.24e-04	26	97	3	PF09380
Domain	FERM_C	EZR RDX MSN	3.63e-04	27	97	3	SM01196
Domain	FERM_PH-like_C	EZR RDX MSN	3.63e-04	27	97	3	IPR018980
Domain	P-type_ATPase_IIC	ATP1A2 ATP1A4	3.95e-04	6	97	2	IPR005775
Domain	FERM_N	EZR RDX MSN	6.62e-04	33	97	3	PF09379
Domain	FERM_N	EZR RDX MSN	6.62e-04	33	97	3	IPR018979
Domain	6hp_glycosidase	PHKA1 PHKA2	7.32e-04	8	97	2	IPR012341
Domain	Na/solute_symporter_CS	SLC5A9 SLC5A3	7.32e-04	8	97	2	IPR018212
Domain	-	PHKA1 PHKA2	7.32e-04	8	97	2	1.50.10.10
Domain	NA_SOLUT_SYMP_1	SLC5A9 SLC5A3	1.42e-03	11	97	2	PS00456
Domain	NA_SOLUT_SYMP_2	SLC5A9 SLC5A3	1.70e-03	12	97	2	PS00457
Domain	SSF	SLC5A9 SLC5A3	1.70e-03	12	97	2	PF00474
Domain	Na/solute_symporter	SLC5A9 SLC5A3	1.70e-03	12	97	2	IPR001734
Domain	NA_SOLUT_SYMP_3	SLC5A9 SLC5A3	1.70e-03	12	97	2	PS50283
Domain	FERM_M	EZR RDX MSN	1.75e-03	46	97	3	PF00373
Domain	6-hairpin_glycosidase-like	PHKA1 PHKA2	2.01e-03	13	97	2	IPR008928
Domain	-	EZR RDX MSN	2.10e-03	49	97	3	1.20.80.10
Domain	FERM_central	EZR RDX MSN	2.10e-03	49	97	3	IPR019748
Domain	FERM_domain	EZR RDX MSN	2.10e-03	49	97	3	IPR000299
Domain	FERM_1	EZR RDX MSN	2.23e-03	50	97	3	PS00660
Domain	FERM_2	EZR RDX MSN	2.23e-03	50	97	3	PS00661
Domain	FERM_3	EZR RDX MSN	2.23e-03	50	97	3	PS50057
Domain	Band_41_domain	EZR RDX MSN	2.23e-03	50	97	3	IPR019749
Domain	B41	EZR RDX MSN	2.23e-03	50	97	3	SM00295
Domain	FERM/acyl-CoA-bd_prot_3-hlx	EZR RDX MSN	2.23e-03	50	97	3	IPR014352
Domain	Sugar/inositol_transpt	SLC2A8 SLC2A2	2.33e-03	14	97	2	IPR003663
Domain	-	ATP1A2 ATP1A4	3.06e-03	16	97	2	1.20.1110.10
Domain	ATPase_P-typ_TM_dom	ATP1A2 ATP1A4	3.06e-03	16	97	2	IPR023298
Domain	HEAT_type_2	RELCH ATR	3.45e-03	17	97	2	IPR021133
Domain	SUGAR_TRANSPORT_2	SLC2A8 SLC2A2	3.45e-03	17	97	2	PS00217
Domain	ATPase_P-typ_cation-transptr_C	ATP1A2 ATP1A4	3.45e-03	17	97	2	IPR006068
Domain	Cation_ATPase_C	ATP1A2 ATP1A4	3.45e-03	17	97	2	PF00689
Domain	Cation_ATPase_N	ATP1A2 ATP1A4	3.87e-03	18	97	2	PF00690
Domain	Cation_ATPase_N	ATP1A2 ATP1A4	3.87e-03	18	97	2	SM00831
Domain	Fd_Rdtase_FAD-bd	NDOR1 DUOX1	4.31e-03	19	97	2	IPR017927
Domain	FAD_FR	NDOR1 DUOX1	4.31e-03	19	97	2	PS51384
Domain	ATPase_P-typ_cation-transptr_N	ATP1A2 ATP1A4	4.31e-03	19	97	2	IPR004014
Domain	Riboflavin_synthase-like_b-brl	NDOR1 DUOX1	4.31e-03	19	97	2	IPR017938
Pathway	WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME	TBC1D3E TBC1D3 TBC1D3H TBC1D3L PNMT TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K	1.77e-10	99	79	10	M46448
Pathway	WP_PTDINS45P2_IN_CYTOKINESIS_PATHWAY	EZR RDX MSN	3.59e-05	12	79	3	M45558
Pathway	REACTOME_CELLULAR_HEXOSE_TRANSPORT	SLC2A8 SLC5A9 SLC2A2	1.54e-04	19	79	3	MM14718
Pathway	REACTOME_CELLULAR_HEXOSE_TRANSPORT	SLC2A8 SLC5A9 SLC2A2	2.09e-04	21	79	3	M27058
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	4.97e-29	11	98	11	16863688
Pubmed	DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.	TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3B TBC1D3G TBC1D3F	1.75e-09	74	98	7	16625196
Pubmed	The ezrin-like family of tyrosine kinase substrates: receptor-specific pattern of tyrosine phosphorylation and relationship to malignant transformation.	EZR RDX MSN	2.17e-08	3	98	3	8479753
Pubmed	Characterization of lens fiber cell triton insoluble fraction reveals ERM (ezrin, radixin, moesin) proteins as major cytoskeletal-associated proteins.	EZR RDX MSN	2.17e-08	3	98	3	18261459
Pubmed	Ezrin, radixin, and moesin are phosphorylated in response to 2-methoxyestradiol and modulate endothelial hyperpermeability.	EZR RDX MSN	2.17e-08	3	98	3	21659656
Pubmed	Expression, localization, and binding activity of the ezrin/radixin/moesin proteins in the mouse testis.	EZR RDX MSN	2.17e-08	3	98	3	19064715
Pubmed	Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement.	EZR RDX MSN	2.17e-08	3	98	3	21864676
Pubmed	Differential expression of ezrin/radixin/moesin (ERM) and ERM-associated adhesion molecules in the blastocyst and uterus suggests their functions during implantation.	EZR RDX MSN	2.17e-08	3	98	3	14613898
Pubmed	Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin.	EZR RDX MSN	2.17e-08	3	98	3	26555866
Pubmed	Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection.	EZR RDX MSN	2.17e-08	3	98	3	23703860
Pubmed	Pseudomonas aeruginosa ExoS ADP-ribosyltransferase inhibits ERM phosphorylation.	EZR RDX MSN	2.17e-08	3	98	3	16889625
Pubmed	Effect of knockdown of ezrin, radixin, and moesin on P-glycoprotein function in HepG2 cells.	EZR RDX MSN	2.17e-08	3	98	3	21837648
Pubmed	Ezrin and moesin function together to promote T cell activation.	EZR RDX MSN	2.17e-08	3	98	3	19124745
Pubmed	Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.	EZR RDX MSN	2.17e-08	3	98	3	22132106
Pubmed	Ezrin-radixin-moesin family proteins are involved in parvovirus replication and spreading.	EZR RDX MSN	2.17e-08	3	98	3	19321616
Pubmed	Deciphering brain-specific transcriptomic expression of Ezr, Rad and Msn genes in the development of Mus musculus.	EZR RDX MSN	2.17e-08	3	98	3	29906485
Pubmed	Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM.	EZR RDX MSN	2.17e-08	3	98	3	31843195
Pubmed	Increased phosphorylation of ezrin/radixin/moesin proteins contributes to proliferation of rheumatoid fibroblast-like synoviocytes.	EZR RDX MSN	2.17e-08	3	98	3	21278069
Pubmed	Nuclear ERM (ezrin, radixin, moesin) proteins: regulation by cell density and nuclear import.	EZR RDX MSN	2.17e-08	3	98	3	15149851
Pubmed	ERM stable knockdown by siRNA reduced in vitro migration and invasion of human SGC-7901 cells.	EZR RDX MSN	2.17e-08	3	98	3	21352885
Pubmed	A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.	EZR RDX MSN	2.17e-08	3	98	3	1429901
Pubmed	ERM Proteins at the Crossroad of Leukocyte Polarization, Migration and Intercellular Adhesion.	EZR RDX MSN	2.17e-08	3	98	3	32098334
Pubmed	Ezrin, Radixin, and Moesin (ERM) proteins function as pleiotropic regulators of human immunodeficiency virus type 1 infection.	EZR RDX MSN	2.17e-08	3	98	3	18295815
Pubmed	Dmoesin controls actin-based cell shape and polarity during Drosophila melanogaster oogenesis.	EZR RDX MSN	2.17e-08	3	98	3	12360288
Pubmed	Dynamics and function of ERM proteins during cytokinesis in human cells.	EZR RDX MSN	2.17e-08	3	98	3	28889652
Pubmed	Control of adipogenesis by ezrin, radixin and moesin-dependent biomechanics remodeling.	EZR RDX MSN	2.17e-08	3	98	3	23116763
Pubmed	Induction of ezrin-radixin-moesin molecules after cryogenic traumatic brain injury of the mouse cortex.	EZR RDX MSN	2.17e-08	3	98	3	21451358
Pubmed	Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation: probing sphingolipid signaling at the outer plasma membrane.	EZR RDX MSN	2.17e-08	3	98	3	20679347
Pubmed	Differential expression and distribution of ezrin, radixin and moesin in human natural killer cells.	EZR RDX MSN	2.17e-08	3	98	3	12385025
Pubmed	Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?	EZR RDX MSN	2.17e-08	3	98	3	25286001
Pubmed	Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.	EZR RDX MSN	2.17e-08	3	98	3	17977945
Pubmed	Ezrin/radixin/moesin proteins are high affinity targets for ADP-ribosylation by Pseudomonas aeruginosa ExoS.	EZR RDX MSN	2.17e-08	3	98	3	15252013
Pubmed	ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation.	EZR RDX MSN	2.17e-08	3	98	3	32160548
Pubmed	The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications.	EZR RDX MSN	2.17e-08	3	98	3	12734202
Pubmed	CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins.	EZR RDX MSN	8.66e-08	4	98	3	27793041
Pubmed	The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival.	EZR RDX MSN	8.66e-08	4	98	3	15096511
Pubmed	Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus.	EZR RDX MSN	8.66e-08	4	98	3	17237445
Pubmed	Mutagenesis of the ezrin-radixin-moesin binding domain of L-selectin tail affects shedding, microvillar positioning, and leukocyte tethering.	EZR RDX MSN	8.66e-08	4	98	3	15178693
Pubmed	Cortical mechanics and meiosis II completion in mammalian oocytes are mediated by myosin-II and Ezrin-Radixin-Moesin (ERM) proteins.	EZR RDX MSN	8.66e-08	4	98	3	20660156
Pubmed	In Vitro and in Vivo Characterization of Molecular Interactions between Calmodulin, Ezrin/Radixin/Moesin, and L-selectin.	EZR RDX MSN	8.66e-08	4	98	3	19129194
Pubmed	Two Sides of the Coin: Ezrin/Radixin/Moesin and Merlin Control Membrane Structure and Contact Inhibition.	EZR RDX MSN	8.66e-08	4	98	3	31018575
Pubmed	Ezrin is a component of the HIV-1 virological presynapse and contributes to the inhibition of cell-cell fusion.	EZR RDX MSN	8.66e-08	4	98	3	24760896
Pubmed	Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.	EZR RDX MSN	8.66e-08	4	98	3	20855527
Pubmed	Functional binding interaction identified between the axonal CAM L1 and members of the ERM family.	EZR RDX MSN	8.66e-08	4	98	3	12070130
Pubmed	Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis.	EZR RDX MSN	8.66e-08	4	98	3	19890007
Pubmed	The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating the activation of ERM proteins.	EZR RDX MSN	8.66e-08	4	98	3	28302370
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3D TBC1D3F	8.66e-08	4	98	3	12359748
Pubmed	Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network.	EZR RDX MSN	8.66e-08	4	98	3	22685202
Pubmed	CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation.	EZR RDX MSN	8.66e-08	4	98	3	21289089
Pubmed	The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes.	EZR RDX MSN	8.66e-08	4	98	3	21148287
Pubmed	Rho-ROCK-dependent ezrin-radixin-moesin phosphorylation regulates Fas-mediated apoptosis in Jurkat cells.	EZR RDX MSN	8.66e-08	4	98	3	18941185
Pubmed	Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.	TBC1D3 TBC1D3D TBC1D3F	8.66e-08	4	98	3	8406013
Pubmed	Human immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host cell death.	EZR RDX MSN	8.66e-08	4	98	3	15818415
Pubmed	Proteomic profiling in pancreatic cancer with and without lymph node metastasis.	EZR RDX MSN	8.66e-08	4	98	3	19152423
Pubmed	LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.	EZR RDX MSN	8.66e-08	4	98	3	19255442
Pubmed	Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout.	EZR RDX MSN	8.66e-08	4	98	3	9890997
Pubmed	The Tre2 (USP6) oncogene is a hominoid-specific gene.	TBC1D3 TBC1D3D TBC1D3C	2.16e-07	5	98	3	12604796
Pubmed	Sensitivity of CYP1A1 mRNA inducibility by dioxin is the same in Cyp1a2(+/+) wild-type and Cyp1a2(-/-) null mutant mice.	EZR RDX MSN	2.16e-07	5	98	3	9464455
Pubmed	Activated ERM protein plays a critical role in drug resistance of MOLT4 cells induced by CCL25.	EZR RDX MSN	2.16e-07	5	98	3	23326330
Pubmed	Regulation of NK cell trafficking by CD81.	EZR RDX MSN	2.16e-07	5	98	3	19830727
Pubmed	A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.	EZR RDX MSN	2.16e-07	5	98	3	23063725
Pubmed	Interplay between RAGE, CD44, and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells.	EZR RDX MSN	2.16e-07	5	98	3	21278261
Pubmed	Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.	TBC1D3 TBC1D3D TBC1D3F	2.16e-07	5	98	3	8471161
Pubmed	Ezrin/radixin/moesin are required for the purinergic P2X7 receptor (P2X7R)-dependent processing of the amyloid precursor protein.	EZR RDX MSN	2.16e-07	5	98	3	22891241
Pubmed	The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho.	EZR RDX MSN	2.16e-07	5	98	3	10806479
Pubmed	Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin.	EZR RDX MSN	2.16e-07	5	98	3	23019340
Pubmed	Anchoring of protein kinase A by ERM (ezrin-radixin-moesin) proteins is required for proper netrin signaling through DCC (deleted in colorectal cancer).	EZR RDX MSN	2.16e-07	5	98	3	25575591
Pubmed	A novel role for BRCA1 in regulating breast cancer cell spreading and motility.	EZR RDX MSN	2.16e-07	5	98	3	21282464
Pubmed	Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes.	EZR RDX MSN	4.31e-07	6	98	3	17515952
Pubmed	Expression of ezrin in subventricular zone neural stem cells and their progeny in adult and developing mice.	EZR RDX MSN	4.31e-07	6	98	3	23229862
Pubmed	Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2.	EZR RDX MSN	4.31e-07	6	98	3	9472040
Pubmed	Human immunodeficiency virus (HIV-1) Vpr induced downregulation of NHE1 induces alteration in intracellular pH and loss of ERM complex in target cells.	EZR RDX MSN	4.31e-07	6	98	3	17349711
Pubmed	Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion.	EZR RDX MSN	4.31e-07	6	98	3	26209696
Pubmed	Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress.	EZR RDX MSN	7.53e-07	7	98	3	22291017
Pubmed	MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression.	EZR RDX MSN	7.53e-07	7	98	3	23264465
Pubmed	VIP regulates CFTR membrane expression and function in Calu-3 cells by increasing its interaction with NHERF1 and P-ERM in a VPAC1- and PKCε-dependent manner.	EZR RDX MSN	1.20e-06	8	98	3	24788249
Pubmed	Finding the Unicorn, a New Mouse Model of Midfacial Clefting.	EZR RDX MSN	1.80e-06	9	98	3	31940751
Pubmed	Radixin regulates cell migration and cell-cell adhesion through Rac1.	EZR RDX MSN	1.80e-06	9	98	3	22467863
Pubmed	Alpha6beta4 integrin and dystroglycan cooperate to stabilize the myelin sheath.	EZR RDX MSN	4.69e-06	12	98	3	18579745
Pubmed	Podoplanin regulates mammary stem cell function and tumorigenesis by potentiating Wnt/β-catenin signaling.	EZR RDX MSN	4.69e-06	12	98	3	29361573
Pubmed	A molecular blueprint at the apical surface establishes planar asymmetry in cochlear hair cells.	EZR RDX MSN	6.08e-06	13	98	3	24135232
Pubmed	Embryo-uterine interaction coordinates mouse embryogenesis during implantation.	EZR RDX MSN	6.08e-06	13	98	3	37522872
Pubmed	Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling.	EZR RDX MSN	7.72e-06	14	98	3	27641493
Pubmed	Expression of ezrin and moesin related to invasion, metastasis and prognosis of laryngeal squamous cell carcinoma.	EZR MSN	7.86e-06	2	98	2	25299115
Pubmed	The multiphosphorylation domain of the phosphorylase kinase alpha M and alpha L subunits is a hotspot of differential mRNA processing and of molecular evolution.	PHKA1 PHKA2	7.86e-06	2	98	2	8226841
Pubmed	Ezrin and moesin expression within the developing human cerebrum and tuberous sclerosis-associated cortical tubers.	EZR MSN	7.86e-06	2	98	2	12111362
Pubmed	Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe.	ATR TIMELESS	7.86e-06	2	98	2	37144518
Pubmed	Perspectives for Ezrin and Radixin in Astrocytes: Kinases, Functions and Pathology.	EZR RDX	7.86e-06	2	98	2	31382374
Pubmed	Expression of ezrin and moesin in primary breast carcinoma and matched lymph node metastases.	EZR MSN	7.86e-06	2	98	2	28624994
Pubmed	WDR34 mutation from anencephaly patients impaired both SHH and PCP signaling pathways.	DYNC2I2 SHH	7.86e-06	2	98	2	32576942
Pubmed	Immunohistochemical assessment of ezrin and moesin in colorectal carcinoma.	EZR MSN	7.86e-06	2	98	2	27042764
Pubmed	Mouse models for ATR deficiency.	NDOR1 ATR	7.86e-06	2	98	2	19782648
Pubmed	Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss.	NDOR1 ATR	7.86e-06	2	98	2	18371340
Pubmed	Moesin: a member of the protein 4.1-talin-ezrin family of proteins.	EZR MSN	7.86e-06	2	98	2	1924289
Pubmed	X-linked liver glycogenosis type II (XLG II) is caused by mutations in PHKA2, the gene encoding the liver alpha subunit of phosphorylase kinase.	PHKA1 PHKA2	7.86e-06	2	98	2	8733133
Pubmed	Specific binding of HIV-1 envelope protein gp120 to the structural membrane proteins ezrin and moesin.	EZR MSN	7.86e-06	2	98	2	9213396
Pubmed	Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site.	EZR MSN	7.86e-06	2	98	2	7579708
Pubmed	Ezrin has properties to self-associate at the plasma membrane.	EZR MSN	7.86e-06	2	98	2	7844168
Pubmed	The Na,K-ATPase alpha4 gene (Atp1a4) encodes a ouabain-resistant alpha subunit and is tightly linked to the alpha2 gene (Atp1a2) on mouse chromosome 1.	ATP1A2 ATP1A4	7.86e-06	2	98	2	10555956
Pubmed	cDNA cloning of a liver isoform of the phosphorylase kinase alpha subunit and mapping of the gene to Xp22.2-p22.1, the region of human X-linked liver glycogenosis.	PHKA1 PHKA2	7.86e-06	2	98	2	1372435
Interaction	GPR17 interactions	PDXDC1 ATR SLC2A8 XPO4 SLC39A4 HEATR1 PIGG SLC5A3 SLC12A9 TIMELESS TARBP1	8.48e-08	283	94	11	int:GPR17
Interaction	ZNF767P interactions	ZNF777 ZNF783 ZNF398 ZNF282	7.74e-07	16	94	4	int:ZNF767P
Interaction	SPN interactions	EZR ATR XPO4 HEATR1 MSN	6.85e-06	57	94	5	int:SPN
Interaction	P2RY8 interactions	XPO4 SLC39A4 HEATR1 PIGG SLC30A7 ATP1A2 ATP1A4	2.07e-05	179	94	7	int:P2RY8
Interaction	TSPAN8 interactions	SHH SNX19 SLC5A3 SLC30A7 SLC38A7	2.64e-05	75	94	5	int:TSPAN8
Interaction	ZNF398 interactions	ZNF777 ZNF783 ZNF398 ZNF282	4.76e-05	43	94	4	int:ZNF398
Interaction	ADORA2B interactions	EZR PIGG SLC5A3 SLC30A7	4.76e-05	43	94	4	int:ADORA2B
Interaction	GPR182 interactions	PDXDC1 RELCH UXS1 ATR TMC6 HEATR1 PIGG SLC5A3 TIMELESS TARBP1	5.19e-05	455	94	10	int:GPR182
Interaction	OPRM1 interactions	ATR XPO4 CLDN8 SLC5A3 SLC38A7 SLC41A1	5.82e-05	144	94	6	int:OPRM1
Interaction	GALNT3 interactions	PDXDC1 SLC39A4 PAPSS1	6.37e-05	17	94	3	int:GALNT3
Interaction	ZNF212 interactions	ZNF777 ZNF783 ZNF398 ZNF282	8.01e-05	49	94	4	int:ZNF212
Interaction	GPR45 interactions	PDXDC1 ATR XPO4 SLC39A4 HEATR1 PIGG SLC5A3 SLC30A7	8.07e-05	300	94	8	int:GPR45
Interaction	GPR173 interactions	SLC39A4 PIGG SLC5A3 SLC30A7	9.38e-05	51	94	4	int:GPR173
Interaction	B3GAT3 interactions	RELCH XPO4 SLC39A4 PIGG SLC30A7	1.00e-04	99	94	5	int:B3GAT3
Interaction	CD70 interactions	PDXDC1 ATR XPO4 HEATR1 PIGG TIMELESS	1.28e-04	166	94	6	int:CD70
Interaction	APH1A interactions	SLC39A4 PDE10A SNX19 SLC38A7	1.77e-04	60	94	4	int:APH1A
Interaction	P2RY2 interactions	XPO4 SLC39A4 HEATR1 PIGG SLC30A7	1.79e-04	112	94	5	int:P2RY2
Interaction	EFNB1 interactions	PDXDC1 EZR RELN XPO4 SLC39A4 HEATR1 TIMELESS	1.92e-04	255	94	7	int:EFNB1
Interaction	MAPK10 interactions	EZR RDX MSN PKMYT1	2.14e-04	63	94	4	int:MAPK10
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 TBC1D3H TBC1D3L PNMT TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	6.31e-16	149	99	12	chr17q12
Cytoband	17q12	TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F	2.56e-06	99	99	5	17q12
Cytoband	7q36.1	ZNF777 ZNF783 ZNF398 ZNF282	2.08e-05	74	99	4	7q36.1
Cytoband	Ensembl 112 genes in cytogenetic band chr7q36	ZNF777 SHH ZNF783 ZNF398 ZNF282	2.57e-05	159	99	5	chr7q36
Cytoband	3q26.2	MYNN SLC7A14	1.56e-03	27	99	2	3q26.2
Cytoband	1q23.2	ATP1A2 ATP1A4	2.61e-03	35	99	2	1q23.2
Cytoband	7q22	RELN SLC12A9	3.08e-03	38	99	2	7q22
GeneFamily	Solute carriers	SLC2A8 SLC5A9 SLC39A4 SLC7A14 SLC2A2 SLC5A3 SLC30A7 SLC12A9 SLC28A2 SLC38A7 SLC41A1	5.15e-08	395	59	11	752
GeneFamily	ATPase Na+/K+ transporting subunits	ATP1A2 ATP1A4	2.18e-04	7	59	2	1208
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	EZR RDX MSN	5.80e-04	50	59	3	1293
CoexpressionAtlas	Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	RELN TBC1D3 TBC1D3H TBC1D3L TBC1D3D TMC6 SLC5A9 PDE10A TBC1D3C TBC1D3B SLC5A3 TBC1D3G TBC1D3K TBC1D3F	1.60e-10	320	95	14	PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	2.56e-10	90	95	9	PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlas	DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TMEM185A PDE10A TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	1.13e-08	242	95	11	PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D PDE10A TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	4.02e-08	213	95	10	PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D PDE10A TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	4.02e-08	213	95	10	PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B MGAT5 TBC1D3G TBC1D3K TBC1D3F	5.27e-07	281	95	10	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B MGAT5 TBC1D3G TBC1D3K TBC1D3F	5.27e-07	281	95	10	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	RELN TBC1D3 TBC1D3H TBC1D3L TBC1D3D TMC6 TMEM185A SLC5A9 PDE10A TBC1D3C TBC1D3B SLC5A3 DERA GAS2L1 MGAT5 TBC1D3G TBC1D3K TBC1D3F	3.07e-06	1153	95	18	PCBC_ratio_MESO-5_vs_SC_cfr-2X-p05
Disease	glycogen storage disease (is_implicated_in)	SLC2A2 PHKA1 PHKA2	2.05e-06	9	87	3	DOID:2747 (is_implicated_in)
Disease	Glycogen phosphorylase kinase deficiency	PHKA1 PHKA2	5.14e-05	4	87	2	cv:C0268147
Disease	systemic lupus erythematosus, chronic lymphocytic leukemia	MYNN MGAT5	1.28e-04	6	87	2	EFO_0000095, MONDO_0007915
Disease	familial hemiplegic migraine (implicated_via_orthology)	ATP1A2 ATP1A4	1.79e-04	7	87	2	DOID:0060178 (implicated_via_orthology)
Disease	primary bacterial infectious disease (implicated_via_orthology)	SHH DUOX1	3.05e-04	9	87	2	DOID:0050338 (implicated_via_orthology)
Disease	nervous system disease (implicated_via_orthology)	ATP1A2 ATP1A4	5.56e-04	12	87	2	DOID:863 (implicated_via_orthology)
Disease	Migraine Disorders	GABRQ ATP1A2	6.56e-04	13	87	2	C0149931
Disease	hypothyroidism (implicated_via_orthology)	PHKA1 DUOX1	6.56e-04	13	87	2	DOID:1459 (implicated_via_orthology)
Disease	macrophage inflammatory protein 1b measurement	TBC1D3 GRM2 TBC1D3B TBC1D3F	7.15e-04	136	87	4	EFO_0008219
Disease	Glycogen storage disease	PHKA1 PHKA2	1.14e-03	17	87	2	cv:C0017919
Disease	Psychoses, Substance-Induced	HTR1A GRM2	1.14e-03	17	87	2	C0033941
Disease	CCL4 measurement	TBC1D3 TBC1D3F	1.58e-03	20	87	2	EFO_0004751
Disease	temporal lobe epilepsy (is_marker_for)	RELN SHH	1.58e-03	20	87	2	DOID:3328 (is_marker_for)
Disease	alpha-tocopherol measurement	CACNA2D1 MGAT5	1.58e-03	20	87	2	EFO_0007898
Disease	neuroimaging measurement, brain volume measurement	PDXDC1 ATR ZNF398 SLC38A7 SLC41A1	1.60e-03	286	87	5	EFO_0004346, EFO_0006930
Disease	Depression, Bipolar	RELN HTR1A SLC5A3	1.67e-03	79	87	3	C0005587
Disease	Psychoses, Drug	HTR1A GRM2	1.74e-03	21	87	2	C0033937
Disease	beta-aminoisobutyric acid measurement	HTR1A PAPSS1	2.27e-03	24	87	2	EFO_0010464
Disease	low density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram	RELN GFRA2	2.27e-03	24	87	2	EFO_0004611, EFO_0006329, EFO_0007871
Disease	Bipolar Disorder	RELN HTR1A PDE10A SLC5A3 TIMELESS ATP1A2	2.90e-03	477	87	6	C0005586

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLGIALLAYVASVWG	UXS1	21	Q8NBZ7
INELITELWSNLEYG	TBC1D32	751	Q96NH3
LLDEIAILWLLGSGY	ACER1	86	Q8TDN7
VGYWAEGLTLDTSLI	GRM2	471	Q14416
ILVLALILGITAWGY	ADAM22	746	Q9P0K1
LLTLGQAWQGYVSDI	DFFB	71	O76075
LLGYSEAAVRGLEWL	C17orf113	476	A0A1B0GUU1
IELAWGFSTVLGILL	ORAI2	146	Q96SN7
LWLGVDALGLNIYEH	RDX	216	P35241
LYNQDLSWLELLPGG	DUOX1	471	Q9NRD9
YQLEQEGTTGWESLL	RELCH	816	Q9P260
RLEGEINTYWGLLDS	KRT40	381	Q6A162
GELVQWSDLITSLYL	MGAT5	296	Q09328
GSTIYLWEFLLALLQ	ELF4	206	Q99607
VILLLIRTWLAEGNY	GABRQ	11	Q9UN88
DNVYSILAVWGLGLA	PHKA1	46	P46020
YWLEAGSANLGLITV	KIAA1109	1066	Q2LD37
GLYSGEVLVWDLSRL	DYNC2I2	236	Q96EX3
AVYLLSALGNGTILW	OR51S1	41	Q8NGJ8
AIGDLIGILELYRHW	PDE10A	196	Q9Y233
LWLSLQYLGLDGFVE	PDXDC1	341	Q6P996
GLLGKYIDRLIQLEW	FAM217B	176	Q9NTX9
ERYLWLLGVGNSLLN	GPR119	261	Q8TDV5
IGLEFILGNYDLWHI	SLC2A2	206	P11168
ILGNYDLWHILLGLS	SLC2A2	211	P11168
LLEFIYTGTLNLDSW	MYNN	76	Q9NPC7
LWLGVDALGLNIYEQ	MSN	216	P26038
LLENGISVWPGYLET	POLG2	406	Q9UHN1
SLSWLYIGLVLLNDL	GDPD2	51	Q9HCC8
YLVVDTDIGLVLLWD	MUC5AC	1001	P98088
WAIGTLLDTNGLYDE	SMPD3	546	Q9NY59
VDFWSLGILVYELLT	PRKG2	631	Q13237
LGSLVWELLDRQGAY	NDOR1	531	Q9UHB4
VLLQYSLNGGLSWSL	RELN	2246	P78509
LLDYSTDGGITWTLL	RELN	2976	P78509
WLGLGIYGIQDSDTL	OASL	486	Q15646
LIGGDLQVLDRVYWN	PAPSS1	376	O43252
DLIIHWGGYSIFLIL	CD1E	296	P15812
VLSLILGYSWLEAVI	ATP1A2	306	P50993
ELLLWQIGCVLLEYG	ATR	226	Q13535
DLLILTWIGGQPVSY	MT-CYB	331	P00156
LQIYWSIHLGLTEGE	GFRA2	106	O00451
LYLLVLAVTEAWGQE	GPHA2	11	Q96T91
WTNVYLDALELGLVI	CACNA2D1	446	P54289
EDLAEWLNALYGLGL	GAS2L1	31	Q99501
LGAIINWLGYSNSLL	HTR1A	381	P08908
EIHSLNVLEGSWILY	CRYGB	121	P07316
VYCDQETSLGGWLLI	FGA	661	P02671
WYLLGIGSEVDIHTI	HEPHL1	991	Q6MZM0
GSYWQRVTLILELLQ	HEATR1	1201	Q9H583
LWLGVDALGLNIYEK	EZR	216	P15311
SLVLTGQWEALYDEI	DERA	161	Q9Y315
LNQEWGLIRYISGLL	PHKA2	816	P46019
GKLIYLLGDSTLRQW	NXPE1	346	Q8N323
DVLARWTDGLLYLGT	PHF1	36	O43189
ILHLGNYLGAIESWV	WARS2	46	Q9UGM6
TGIQSLIEGLLQYSW	DARS2	291	Q6PI48
SQLLYQIGTWLLDSE	SHH	436	Q15465
VLLALRLDGIIQWSY	TMEM185A	26	Q8NFB2
VVGILLAYLAGWVLE	SLC2A8	166	Q9NY64
GWTVLLLLSLYEDDI	SLC39A4	631	Q6P5W5
WVLVSYGVLLVTLGA	SLC38A7	431	Q9NVC3
QESLGWNLYVSVILL	SLC5A3	151	P53794
ALGWNLYLSTGILLV	SLC5A9	181	Q2M3M2
TLALLSGISWGLYLE	SLC41A1	266	Q8IVJ1
GISLGLTLRLWDVYL	TBC1D3L	276	B9A6J9
LSWLGELVDIQGLTF	SLC28A2	441	O43868
ALSLLLGYGWLEAII	ATP1A4	316	Q13733
LGEALYLGWTTALVL	CLDN8	161	P56748
LLLIGALEESWYLAG	PNMT	211	P11086
GWNLILEYLIGTAAG	SLC7A14	136	Q8TBB6
ASLNGLEIIWAEYSL	STK31	406	Q9BXU1
GISLGLTLRLWDVYL	TBC1D3B	276	A6NDS4
GISLGLTLRLWDVYL	TBC1D3H	276	P0C7X1
GVLSETLYELLQLGW	TIMELESS	131	Q9UNS1
ELIYLLEHGQELWTV	ZNF599	56	Q96NL3
WLILVTGYLLADDTQ	XPO4	541	Q9C0E2
TWLGLLEEAYTLVQH	NIBAN1	271	Q9BZQ8
GISLGLTLRLWDVYL	TBC1D3F	276	A6NER0
VRLEQAWEEGGILYL	PKMYT1	171	Q99640
AWEEGGILYLQTELC	PKMYT1	176	Q99640
WAVLGTLLQEYGLLQ	ZNF398	96	Q8TD17
AAVLYSWGLVQLVLL	SLC12A9	396	Q9BXP2
IILALSLAYEWLQKG	MT-ND3	96	P03897
LTLDLSDGLLYWLVQ	ROS1	836	P08922
GISLGLTLRLWDVYL	TBC1D3E	276	A0A087X179
YLLLGQRLEGLDTGW	SPTB	1136	P11277
YLLLLQESIWPGGVL	SNX19	876	Q92543
VELLYGIWSNCLGLI	SLC30A7	51	Q8NEW0
LLQGAGDIWLDVYKL	WDR93	211	Q6P2C0
DALGLVEYLNEWLQI	PSMG2	216	Q969U7
GISLGLTLRLWDVYL	TBC1D3D	276	A0A087WVF3
RNVLELIYGQTLTWL	TMC6	591	Q7Z403
GALLIWEYTRQQLLS	TARBP1	1601	Q13395
TVGLWEIYSGLVLLA	PIGG	791	Q5H8A4
SKWVVLGTLLQEYGL	ZNF777	236	Q9ULD5
GISLGLTLRLWDVYL	TBC1D3G	276	Q6DHY5
GISLGLTLRLWDVYL	TBC1D3	276	Q8IZP1
GISLGLTLRLWDVYL	TBC1D3K	276	A0A087X1G2
WAVLGTLLQEYGLLQ	ZNF282	151	Q9UDV7
GISLGLTLRLWDVYL	TBC1D3I	276	A0A087WXS9
GISLGLTLRLWDVYL	TBC1D3C	276	Q6IPX1
EWLLVGTKQGHLLLY	VPS39	26	Q96JC1
WAVLGTLLQEYGLLQ	ZNF783	96	Q6ZMS7
LSYIEVLTDGSLVGW	GRIN2D	201	O15399