Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity	HS3ST3B1 HS3ST3A1	1.92e-05	2	88	2	GO:0033872
Domain	Striatin	STRN3 STRN4	6.56e-05	3	88	2	PF08232
Domain	Striatin_N	STRN3 STRN4	6.56e-05	3	88	2	IPR013258
Domain	PPR	PTCD1 MRPS27	6.03e-04	8	88	2	PS51375
Domain	ABC_A	ABCA1 ABCA10	1.40e-03	12	88	2	IPR026082
Domain	P-loop_NTPase	ABCA1 GTPBP2 SAMD9 DRG2 MYO18A ASPM CHD3 HS3ST3B1 HS3ST3A1 ABCA10 AQR	2.08e-03	848	88	11	IPR027417
Domain	-	ABCA1 GTPBP2 SAMD9 DRG2 MYO18A CHD3 HS3ST3B1 HS3ST3A1 ABCA10 AQR	2.64e-03	746	88	10	3.40.50.300
Domain	Myosin-like_IQ_dom	MYO18A ASPM	3.56e-03	19	88	2	IPR027401
Domain	-	MYO18A ASPM	3.56e-03	19	88	2	4.10.270.10
Domain	Pentatricopeptide_repeat	PTCD1 MRPS27	5.21e-03	23	88	2	IPR002885
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	TYK2 UBR1 FRAS1 GTPBP2 SAMD9 MAP1B MCU MARF1 CHD3 ZZEF1 AQR CDC45	1.19e-07	650	90	12	38777146
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	SOX4 ASAP2 STX18 CSNK1A1 CDC16 MCU VPS50 MARF1 NINL MINDY4 OCRL NME7 FMNL2 EDRF1 PKN3 PHLDB2	2.61e-07	1321	90	16	27173435
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TYK2 TRIM33 GTPBP2 ANKRD2 CDC16 VPS50 CAPRIN2 ASPM CHD3 CSMD1 ZZEF1 FMNL2 PHLDB2 ZNF518A	1.06e-06	1116	90	14	31753913
Pubmed	Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells.	CSNK1A1L CSNK1A1	6.62e-06	2	90	2	23354688
Pubmed	Tissue-specific distribution of mouse casein kinase I alpha mRNA.	CSNK1A1L CSNK1A1	6.62e-06	2	90	2	9522121
Pubmed	Drosophila glucome screening identifies Ck1alpha as a regulator of mammalian glucose metabolism.	CSNK1A1L CSNK1A1	6.62e-06	2	90	2	25994086
Pubmed	CSNK1A1/CK1α suppresses autoimmunity by restraining the CGAS-STING1 signaling.	CSNK1A1L CSNK1A1	6.62e-06	2	90	2	37723657
Pubmed	Casein Kinase 1α Regulates Testosterone Synthesis and Testis Development in Adult Mice.	CSNK1A1L CSNK1A1	6.62e-06	2	90	2	36929849
Pubmed	A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry.	HS3ST3B1 HS3ST3A1	6.62e-06	2	90	2	10520990
Pubmed	Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1.	HS3ST3B1 HS3ST3A1	6.62e-06	2	90	2	15304505
Pubmed	Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso.	HS3ST3B1 HS3ST3A1	6.62e-06	2	90	2	22475533
Pubmed	Class III β-Tubulin Expression Is of Value in Selecting nab -Paclitaxel and Gemcitabine as First-Line Therapy in Unresectable Pancreatic Cancer.	CSNK1A1L CSNK1A1	6.62e-06	2	90	2	35695793
Pubmed	Exploring the role of casein kinase 1α splice variants across cancer cell lines.	CSNK1A1L CSNK1A1	6.62e-06	2	90	2	38852281
Pubmed	Casein kinase 1 alpha regulates chromosome congression and separation during mouse oocyte meiotic maturation and early embryo development.	CSNK1A1L CSNK1A1	6.62e-06	2	90	2	23690993
Pubmed	Csnk1a1 inhibition modulates the inflammatory secretome and enhances response to radiotherapy in glioma.	CSNK1A1L CSNK1A1	6.62e-06	2	90	2	34216174
Pubmed	Casein Kinase 1α as a Novel Factor Affects Thyrotropin Synthesis via PKC/ERK/CREB Signaling.	CSNK1A1L CSNK1A1	6.62e-06	2	90	2	37108197
Pubmed	Knockdown of Csnk1a1 results in preimplantation developmental arrest in mice.	CSNK1A1L CSNK1A1	6.62e-06	2	90	2	36542875
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	CSNK1A1L MAP1B PTCD1 RSL1D1 CDC16 TBCK PBK MRPS27 CHD3 NSMCE3 PLOD2 TERF2IP SDHA CDC45	8.34e-06	1335	90	14	29229926
Pubmed	Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.	CSNK1A1L CSNK1A1 RSL1D1 CHD3	1.39e-05	56	90	4	26919559
Pubmed	CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation.	CSNK1A1L CSNK1A1	1.98e-05	3	90	2	28878021
Pubmed	Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.	CSNK1A1L CSNK1A1	1.98e-05	3	90	2	26811327
Pubmed	Assignment of a locus for autosomal dominant idiopathic scoliosis (IS) to human chromosome 17p11.	HS3ST3B1 HS3ST3A1	1.98e-05	3	90	2	12384783
Pubmed	Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling.	CSNK1A1L CSNK1A1	1.98e-05	3	90	2	19805514
Pubmed	Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia.	CSNK1A1L CSNK1A1	1.98e-05	3	90	2	24616378
Pubmed	Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.	CSNK1A1L CSNK1A1	1.98e-05	3	90	2	25242043
Pubmed	Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.	CSNK1A1L CSNK1A1	1.98e-05	3	90	2	28655862
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	FAM184B FRAS1 DRG2 STX18 PTCD1 RSL1D1 MYO18A ASPM MRPS27 NME7 PLOD2 EDRF1 AQR SDHA	2.77e-05	1487	90	14	33957083
Pubmed	Collaborative effect of Csnk1a1 haploinsufficiency and mutant p53 in Myc induction can promote leukemic transformation.	CSNK1A1L CSNK1A1	3.96e-05	4	90	2	38147624
Pubmed	The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic.	CSNK1A1L CSNK1A1	3.96e-05	4	90	2	32728212
Pubmed	Biosynthesis of heparin/heparan sulfate. The D-glucosaminyl 3-O-sulfotransferase reaction: target and inhibitor saccharides.	HS3ST3B1 HS3ST3A1	3.96e-05	4	90	2	7744762
Pubmed	Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities.	HS3ST3B1 HS3ST3A1	3.96e-05	4	90	2	9988768
Pubmed	FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning.	CSNK1A1L CSNK1A1	3.96e-05	4	90	2	31338967
Pubmed	Osteoadherin accumulates in the predentin towards the mineralization front in the developing tooth.	OMD BGN	3.96e-05	4	90	2	22355375
Pubmed	Cx43 phosphorylation sites regulate pancreatic cancer metastasis.	CSNK1A1L CSNK1A1	3.96e-05	4	90	2	33603164
Pubmed	Regulation of p53-MDMX interaction by casein kinase 1 alpha.	CSNK1A1L CSNK1A1	3.96e-05	4	90	2	16024788
Pubmed	Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain.	STRN3 STRN4	3.96e-05	4	90	2	10748158
Pubmed	A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma.	CSNK1A1L CSNK1A1	3.96e-05	4	90	2	30487124
Pubmed	MxA interacts with and is modified by the SUMOylation machinery.	CHD3 TDG ZNF251	4.69e-05	27	90	3	25447205
Pubmed	Crbn I391V is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice.	CSNK1A1L CSNK1A1	6.59e-05	5	90	2	30064974
Pubmed	A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism.	CSNK1A1L CSNK1A1	6.59e-05	5	90	2	23890787
Pubmed	Mutational analysis of genes with ureteric progenitor cell-specific expression in branching morphogenesis of the mouse kidney.	HS3ST3B1 HS3ST3A1	6.59e-05	5	90	2	32017326
Pubmed	CK1α deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3β pathway and inhibiting Foxa2 expression through p53 pathway†.	CSNK1A1L CSNK1A1	6.59e-05	5	90	2	37944068
Pubmed	Glutaredoxin 1 protects lens epithelial cells from epithelial-mesenchymal transition by preventing casein kinase 1α S-glutathionylation during posterior capsular opacification.	CSNK1A1L CSNK1A1	6.59e-05	5	90	2	36989576
Pubmed	CKIα ablation highlights a critical role for p53 in invasiveness control.	CSNK1A1L CSNK1A1	6.59e-05	5	90	2	21331045
Pubmed	Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome.	CSNK1A1L CSNK1A1	6.59e-05	5	90	2	30651631
Pubmed	The armadillo repeat domain of the APC tumor suppressor protein interacts with Striatin family members.	STRN3 STRN4	6.59e-05	5	90	2	18502210
Pubmed	Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer.	CSNK1A1L CSNK1A1	6.59e-05	5	90	2	25628462
Pubmed	Deficiency of lysyl hydroxylase 2 in mice causes systemic endoplasmic reticulum stress leading to early embryonic lethality.	ATF4 PLOD2	6.59e-05	5	90	2	30905411
Pubmed	Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2.	ATF4 PLOD2 BGN	8.64e-05	33	90	3	18424556
Pubmed	An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.	CSNK1A1L CSNK1A1 CDC16	8.64e-05	33	90	3	30783098
Pubmed	Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways.	CSNK1A1L CSNK1A1	9.87e-05	6	90	2	11884395
Pubmed	Physiological role for casein kinase 1 in glutamatergic synaptic transmission.	CSNK1A1L CSNK1A1	9.87e-05	6	90	2	16014721
Pubmed	MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.	CSNK1A1L CSNK1A1	9.87e-05	6	90	2	33667384
Pubmed	Protein kinase CK1alpha regulates mRNA binding by heterogeneous nuclear ribonucleoprotein C in response to physiologic levels of hydrogen peroxide.	CSNK1A1L CSNK1A1	9.87e-05	6	90	2	15687492
Pubmed	Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival.	CSNK1A1L CSNK1A1	9.87e-05	6	90	2	19118383
Pubmed	MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling.	CSNK1A1L CSNK1A1	9.87e-05	6	90	2	32511789
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	TRIM33 CDC16 VPS50 STRN4 PBK AQR SDHA CDC45	1.05e-04	560	90	8	35241646
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TYK2 PLEKHH1 ASAP2 MAP1B CSNK1A1 TBCK SLITRK3 CHD3 CSMD1 SLC4A5 ZNF595 TERF2IP TSPAN9	1.18e-04	1489	90	13	28611215
Pubmed	Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.	HIP1 MAST4 TCFL5 SDHA	1.21e-04	97	90	4	22360420
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	TRIM33 STRN3 HIP1 STX18 PTCD1 CSNK1A1 CDC16 STRN4 MRPS27 EDRF1 TERF2IP AQR SDHA	1.24e-04	1497	90	13	31527615
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TYK2 DOCK3 SOX4 FRAS1 HIP1 STRN4 NINL ZZEF1 PKN3 SDHA TRAK1	1.33e-04	1105	90	11	35748872
Pubmed	Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.	CSNK1A1L CSNK1A1	1.38e-04	7	90	2	25644602
Pubmed	The synovial sarcoma SYT-SSX2 oncogene remodels the cytoskeleton through activation of the ephrin pathway.	CSNK1A1L CSNK1A1	1.38e-04	7	90	2	17686994
Pubmed	NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly.	CSNK1A1L CSNK1A1	1.38e-04	7	90	2	34615873
Pubmed	Functional proteomics mapping of a human signaling pathway.	MAST4 CHD3 TDG ZZEF1 FMNL2 ZNF251 ZNF518A TRAK1	1.51e-04	591	90	8	15231748
Pubmed	Casein kinase 1 delta (CK1delta) interacts with the SNARE associated protein snapin.	CSNK1A1L CSNK1A1	1.84e-04	8	90	2	17101137
Pubmed	The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1.	CSNK1A1L CSNK1A1	1.84e-04	8	90	2	21930935
Pubmed	Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif.	CHD3 TDG	1.84e-04	8	90	2	10961991
Pubmed	Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism.	CSNK1A1L CSNK1A1	1.84e-04	8	90	2	17244647
Pubmed	Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun.	TDG ATF4	1.84e-04	8	90	2	1631061
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	UBR1 STRN3 CDC16 STRN4 ZZEF1	2.32e-04	212	90	5	33853758
Pubmed	Effects of Fam83h truncation mutation on enamel developmental defects in male C57/BL6J mice.	CSNK1A1L CSNK1A1	2.36e-04	9	90	2	36272714
Pubmed	Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta.	CSNK1A1L CSNK1A1	2.36e-04	9	90	2	9601641
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	STRN3 CDC16 STRN4 MRPS27 NINL NME7 ADGRG4 PHLDB2	2.57e-04	639	90	8	23443559
Pubmed	Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7.	CSNK1A1L CSNK1A1	2.94e-04	10	90	2	25500533
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	DRG2 MAP1B CSNK1A1 RSL1D1 VPS50 MRPS27 AQR	3.18e-04	498	90	7	36634849
Pubmed	The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.	UBR1 HIP1 VPS50 MYO18A MRPS27	3.37e-04	230	90	5	35449600
Pubmed	Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.	ASAP2 MARF1 ZZEF1	3.38e-04	52	90	3	9455477
Pubmed	Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex.	CSNK1A1L CSNK1A1	3.59e-04	11	90	2	21709260
Pubmed	Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy.	OMD BGN	3.59e-04	11	90	2	12796502
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	STRN3 DRG2 MAST4 CSNK1A1 MCU NINL MINDY4 OCRL NME7	3.70e-04	853	90	9	28718761
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DRG2 MAST4 MAP1B CSNK1A1 PLEKHM3 EDRF1 AQR PHLDB2 TRAK1	3.95e-04	861	90	9	36931259
Pubmed	Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function.	FAM184B MCU SDHA	3.99e-04	55	90	3	29111377
Pubmed	Protein interaction analysis of senataxin and the ALS4 L389S mutant yields insights into senataxin post-translational modification and uncovers mutant-specific binding with a brain cytoplasmic RNA-encoded peptide.	CHD3 TDG	4.30e-04	12	90	2	24244371
Pubmed	Peli1 Modulates the Subcellular Localization and Activity of Mdmx.	CSNK1A1L CSNK1A1	4.30e-04	12	90	2	29523541
Pubmed	Replication of top markers of a genome-wide association study in multiple sclerosis in Spain.	ASAP2 CSMD1	4.30e-04	12	90	2	20944657
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	STRN3 STX18 RSL1D1 MCU STRN4 MRPS27 MINDY4 OCRL ZZEF1 SDHA TRAK1 CDC45	4.73e-04	1496	90	12	32877691
Pubmed	HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction.	STRN3 STRN4	5.07e-04	13	90	2	23277359
Pubmed	Casein kinase 1α mediates estradiol secretion via CYP19A1 expression in mouse ovarian granulosa cells.	CSNK1A1L CSNK1A1	5.91e-04	14	90	2	39183304
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	FRAS1 COL6A5 BGN	6.23e-04	64	90	3	22261194
Pubmed	Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.	ZNF91 ZNF595	6.80e-04	15	90	2	15885501
Pubmed	E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3.	MYO18A ATF4	6.80e-04	15	90	2	18276110
Pubmed	Kinome siRNA screen identifies regulators of ciliogenesis and hedgehog signal transduction.	CSNK1A1L CSNK1A1	6.80e-04	15	90	2	18827223
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	FRAS1 DRG2 MAP1B RSL1D1 MRPS27 CHD3	7.00e-04	410	90	6	26949251
Pubmed	TRIM27 cooperates with STK38L to inhibit ULK1-mediated autophagy and promote tumorigenesis.	CSNK1A1L CSNK1A1 PHLDB2	7.12e-04	67	90	3	35670107
Pubmed	The COP9 signalosome mediates beta-catenin degradation by deneddylation and blocks adenomatous polyposis coli destruction via USP15.	CSNK1A1L CSNK1A1	7.76e-04	16	90	2	19576224
Pubmed	Multiple isoforms of heparan sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cdnas and identification of distinct genomic loci.	HS3ST3B1 HS3ST3A1	7.76e-04	16	90	2	9988767
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	MAP1B RSL1D1 MYO18A ASPM MRPS27 CHD3 TERF2IP AQR	7.97e-04	759	90	8	35915203
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	STRN3 CSNK1A1L CSNK1A1 RSL1D1 CDC16 STRN4 ASPM NSMCE3 PLOD2 AQR	8.11e-04	1155	90	10	20360068
Pubmed	Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.	TYK2 TRIM33 CSNK1A1L CSNK1A1	8.30e-04	161	90	4	36398662
GeneFamily	Small leucine rich repeat proteoglycans	OMD BGN	6.54e-04	12	58	2	573
GeneFamily	ATP binding cassette subfamily A	ABCA1 ABCA10	8.98e-04	14	58	2	805
GeneFamily	WD repeat domain containing\|Protein phosphatase 2 regulatory subunits	STRN3 STRN4	1.03e-03	15	58	2	696
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	STRN3 STRN4	1.85e-03	20	58	2	1371
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHH1 ASAP2 PLEKHM3 PHLDB2	4.30e-03	206	58	4	682
GeneFamily	Sulfotransferases, membrane bound	HS3ST3B1 HS3ST3A1	6.27e-03	37	58	2	763
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX4 OMD HS3ST3A1 ABCA10 BGN SPIC	2.99e-06	197	90	6	5fbbc570a4e77c703f569a4f85ce2d8af67d6297
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD13C CAPRIN2 ZNF251 NLRC3 CDC45	2.07e-05	164	90	5	5621c2e3fae84d5a2e4f1595e454bcb3a2b3f93c
ToppCell	Ionocyte\|World / shred by cell class for turbinate	SOX4 HS3ST3A1 FMNL2 RCAN2 SPIC	2.13e-05	165	90	5	0cb2199b87f17ece743fb2652b2f448dfa78ae0b
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PBK ASPM OMD BGN CDC45	2.99e-05	177	90	5	4197cf2b1e743230c821f422836fa5991b155a52
ToppCell	Pericytes-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	CSNK1A1L MAP1B OMD RCAN2 BGN	3.07e-05	178	90	5	a2448d868da2abe48c394c51264aad03e866dfec
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK3 MAST4 ANKRD2 PXYLP1 RCAN2	3.41e-05	182	90	5	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	Basal\|World / shred by cell class for mouse tongue	SOX4 ABCA1 HIP1 ASAP2 MAP1B	3.50e-05	183	90	5	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac\|Myeloid_cells / Location, Cell class and cell subclass	UBR1 STRN3 CHD3 ZNF251 PHLDB2	3.78e-05	186	90	5	701eea0016d69f0f9d29b613948f91239096e6c7
ToppCell	severe-Others-Megakaryocytes\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ASAP2 ARMC3 MAP1B PLOD2 TSPAN9	3.88e-05	187	90	5	ef16331d1e5abe6bde7f09793c4a87a6ac24e592
ToppCell	COPD-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	HIP1 MAP1B PXYLP1 RCAN2 BGN	3.88e-05	187	90	5	406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FRAS1 MAP1B PLOD2 TSPAN9 BGN	3.98e-05	188	90	5	ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	MAST4 ANKRD2 HS3ST3A1 PHLDB2 RCAN2	4.19e-05	190	90	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	Control-PLT_1\|World / Disease Group and Platelet Clusters	GTPBP2 ASAP2 ARMC3 NSMCE3 SDHA	4.40e-05	192	90	5	f595eba81911eb860dce964f1d8269287f50d3ea
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OMD HS3ST3A1 ABCA10 BGN SPIC	4.51e-05	193	90	5	c5bd0ed6f57459e54d2463318e8d9b1879718e63
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FRAS1 MAP1B OMD PLOD2 BGN	4.97e-05	197	90	5	63b63c6b2f842adb87bc83222ff86796bd9b58f6
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FRAS1 MAP1B OMD PLOD2 BGN	4.97e-05	197	90	5	fb50903b87498b400c8e16e6a561b6d9458e5d97
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SOX4 CHD3 HS3ST3A1 PLOD2 BGN	5.09e-05	198	90	5	c55608633f66e3d434c5d81324efb07c5120d2c2
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SOX4 CHD3 HS3ST3A1 PLOD2 BGN	5.09e-05	198	90	5	3e5459038fc6ed95f529eb4d1dc5113e16c19012
ToppCell	facs-Trachea-nan-3m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OMD HS3ST3B1 HS3ST3A1 PLOD2 BGN	5.09e-05	198	90	5	71e847e8c24744d6df4a960348ad2ecf310373b4
ToppCell	3'-Broncho-tracheal-Mesenchymal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1B OMD ABCA10 RCAN2 BGN	5.09e-05	198	90	5	4961a3e9b953679648586afed04869ff36b81820
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1B COL6A5 OMD ABCA10 BGN	5.22e-05	199	90	5	fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	RNASEH2B FAM184B MAST4 ASPM CDC45	5.34e-05	200	90	5	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Mesothelium\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	FRAS1 MAP1B PLOD2 PHLDB2 BGN	5.34e-05	200	90	5	c082bc21ec7c5323439d108ea8aea510e1113c3f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	RNASEH2B FAM184B MAST4 ASPM CDC45	5.34e-05	200	90	5	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Cdc20)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ESRP1 PBK ASPM PKN3	1.44e-04	131	90	4	f9fb8d74ca720b81fd5910cc975510359a8ef751
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TOPAZ1 PBK PKN3 CDC45	1.81e-04	139	90	4	b07929348ec9ad95d7bce33a7deac0938227b19f
ToppCell	Parenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_systemic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	GTPBP2 MAP1B ESRP1 RCAN2	1.92e-04	141	90	4	dcc56aef1b31bfe0de84cb0b5c77d242681cf19c
ToppCell	Bronchus_Control_(B.)-Immune-TX-TRAM-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	FAM184B ANKRD13C ZNF425 NLRC3	2.25e-04	147	90	4	50a855aa7f214c3be8ac46a22adf9bc9dd0285db
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	UBR1 MAST4 ASPM NLRC3	2.31e-04	148	90	4	80470353e12599440f711b6e107730763376d04d
ToppCell	normal_Lung-Endothelial_cells-Tumor_ECs\|Endothelial_cells / Location, Cell class and cell subclass	PBK ASPM ABCA10 RCAN2	2.68e-04	154	90	4	afdc385397c7b13c9348eeef95f109f2363057ae
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK3 MYO1H RCAN2 CDC45	2.75e-04	155	90	4	cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HIP1 PLEKHM3 MINDY4 FMNL2	2.89e-04	157	90	4	432b8719a8afd289cf48068e12c26a349d753fcc
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX4 FAM184B LCA5L BGN	2.89e-04	157	90	4	beab0ac47202266b04543c02cfcdda012375e879
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ABCA10 ADGRG4 TRAK1	2.96e-04	158	90	4	7960337d87afecf2692ab65e5991f052ceddfacc
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184B FRAS1 ESRP1 NLRC3	3.03e-04	159	90	4	4000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184B FRAS1 ESRP1 NLRC3	3.03e-04	159	90	4	7619d0d49738dd08daf01b42664691a5323aa793
ToppCell	COVID-CD4-CD4_Treg\|COVID / Condition, Cell_class and T cell subcluster	STRN3 MAST4 PTCD1 PXYLP1	3.03e-04	159	90	4	037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 AOC1 SLITRK3 SPIC	3.25e-04	162	90	4	0ccdb224ee3c585a6d0caffde5608d9d3cc452f8
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 AOC1 SLITRK3 SPIC	3.25e-04	162	90	4	0d35752a7249b3c62b8007ec8a775c37d16b8d31
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 AOC1 SLITRK3 SPIC	3.25e-04	162	90	4	9ccee8e7e78e16b0149a94867e12d86d3b04f9b9
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAP1B ASPM CSMD1 RCAN2	3.33e-04	163	90	4	51dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 PBK ASPM SPIC	3.49e-04	165	90	4	0ae39c9a6d1265d65dc0660924612cfe11e489ec
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ASAP2 MAP1B PLOD2 TSPAN9	3.49e-04	165	90	4	6799a6580c667738995cceb31cbf1c7fbdc4ff84
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ASAP2 MAP1B PLOD2 TSPAN9	3.49e-04	165	90	4	8329d780f244bc31344443b29e5a00529a016662
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 PBK ASPM SPIC	3.49e-04	165	90	4	686cf89077cc7b744a6127de2b34d8c27da8b6c4
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 PBK ASPM SPIC	3.49e-04	165	90	4	a5ed8c331d5551cd8bce50bdc31cb893218317cd
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAM184B FRAS1 ESRP1 NLRC3	3.57e-04	166	90	4	bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCell	CV-Mild-3\|Mild / Virus stimulation, Condition and Cluster	SOX4 ZNF595 PHLDB2 CDC45	3.57e-04	166	90	4	5599f90fc0e15a3670b03187085eba91228390a2
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPRIN2 PBK PXYLP1 CDC45	3.57e-04	166	90	4	21ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCell	Ionocyte-iono-3\|World / Class top	HIP1 PBK TDG RCAN2	3.57e-04	166	90	4	9c4a780f8af46d7552077c7a0ae0ab1b2413e5d4
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAM184B FRAS1 ESRP1 NLRC3	3.57e-04	166	90	4	5e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	HS3ST3A1 PKN3 BGN CDC45	3.65e-04	167	90	4	9062577a4b7902c9a888d706589d1b05221c0fa8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PBK ASPM PKN3 CDC45	3.82e-04	169	90	4	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 PBK OMD CDC45	3.82e-04	169	90	4	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	MYO1H PBK ASPM CDC45	3.90e-04	170	90	4	5319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B PBK ASPM CDC45	3.99e-04	171	90	4	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B PBK ASPM CDC45	3.99e-04	171	90	4	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	PBK ASPM CHD3 OMD	4.26e-04	174	90	4	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	droplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CAPRIN2 PBK PXYLP1 CDC45	4.35e-04	175	90	4	6751ee4b312d7f87275f2c35e5878cfc3be3ebe3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ESRP1 PBK ASPM CDC45	4.35e-04	175	90	4	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCA5L PLEKHM3 HS3ST3A1 FMNL2	4.45e-04	176	90	4	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B PHLDB2 RCAN2 BGN	4.45e-04	176	90	4	90f36f10c6ed440a0ca549f23219398853f1fbc3
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL6A5 HS3ST3A1 SLC4A5 BGN	4.45e-04	176	90	4	852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 ANKRD2 PXYLP1 RCAN2	4.45e-04	176	90	4	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCA5L PLEKHM3 HS3ST3A1 FMNL2	4.45e-04	176	90	4	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL6A5 HS3ST3A1 SLC4A5 BGN	4.45e-04	176	90	4	d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	SOX4 MAP1B ZNF91	4.53e-04	74	90	3	a50df7f4f7847b8aeff3fc6d521a69b50e05c719
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 ESRP1 PLOD2 PHLDB2	4.54e-04	177	90	4	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MAP1B LCA5L OMD BGN	4.64e-04	178	90	4	8f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCell	ASK440-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	ASPM COL6A5 PLOD2 BGN	4.64e-04	178	90	4	86f1741636ed3e85bb4a65f84949b718fc38c290
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FRAS1 HS3ST3A1 PLOD2 BGN	4.64e-04	178	90	4	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega\|lymph-node_spleen / Manually curated celltypes from each tissue	ARMC3 COL6A5 PLOD2 TSPAN9	4.74e-04	179	90	4	4e0cf069bc47328eda753a4edc7e89b8915d52bb
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CSNK1A1L PBK ASPM CDC45	4.84e-04	180	90	4	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRAS1 MAP1B ASPM PHLDB2	4.94e-04	181	90	4	65eaa9bc1022bcf0c5f0f92c07a2cbbf11f9b59c
ToppCell	IIH-cycling-\|IIH / Condition, Cell_class and T cell subcluster	ANKRD2 PBK ASPM CDC45	4.94e-04	181	90	4	7f4fed9e296bc22cb5a1e6c8e3c4b641e97c3078
ToppCell	IIH-cycling\|IIH / Condition, Cell_class and T cell subcluster	ANKRD2 PBK ASPM CDC45	4.94e-04	181	90	4	ec3e782ce93dcfe1a54fb7284e4e39063614b0e2
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(PRG4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRAS1 MAP1B ASPM PHLDB2	4.94e-04	181	90	4	eaac7d58117eddfff06b25521efc431c1351d592
ToppCell	droplet-Lung-nan-3m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPRIN2 ESRP1 COL6A5 SLC4A5	5.05e-04	182	90	4	cfba75c1ffc39ac76db9e8e27394731942882b30
ToppCell	droplet-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPRIN2 ESRP1 COL6A5 SLC4A5	5.05e-04	182	90	4	d836bfdc298ecd3558a973e393a329eb8bd59d79
ToppCell	COVID-19-kidney-CD-IC-B\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ASAP2 NINL PHLDB2 RCAN2	5.05e-04	182	90	4	ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCell	severe_influenza-Platelet\|severe_influenza / disease group, cell group and cell class (v2)	ASAP2 MAP1B PLOD2 TSPAN9	5.05e-04	182	90	4	2018b71ec26bf3cd7ecdc04d5473900a697cd58a
ToppCell	droplet-Lung-nan-3m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPRIN2 ESRP1 COL6A5 SLC4A5	5.05e-04	182	90	4	7e7c7a26460d3003cdf0c0ffb96208a566aa09a7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PBK ASPM OMD CDC45	5.15e-04	183	90	4	ba7753e9fe2a6a87c5264f299ac97da2ddbda178
ToppCell	COVID-19-kidney-Podocyte\|kidney / Disease (COVID-19 only), tissue and cell type	MAP1B HS3ST3B1 HS3ST3A1 BGN	5.15e-04	183	90	4	fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell	Control-T/NK_proliferative\|Control / Disease group and Cell class	MCU PBK ASPM CDC45	5.15e-04	183	90	4	09c2b4e630f1c338f02c1242e3598e870d6b0a28
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RNASEH2B CAPRIN2 PBK CDC45	5.15e-04	183	90	4	6c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCell	Mesenchymal_cells-Chondrocytes\|World / Lineage and Cell class	OMD HS3ST3B1 HS3ST3A1 PLOD2	5.26e-04	184	90	4	1e03f9f08de5ad4d45388a95afad9f23ff0d0e28
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|lymph-node_spleen / Manually curated celltypes from each tissue	ARMC3 MCU PLOD2 TSPAN9	5.26e-04	184	90	4	10607d7d92edcbb92d992900086b90b307421cc3
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CSNK1A1L OMD ABCA10 BGN	5.26e-04	184	90	4	4d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CAPRIN2 PBK PXYLP1 CDC45	5.37e-04	185	90	4	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 MAP1B RCAN2 BGN	5.37e-04	185	90	4	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	OMD HS3ST3A1 PLOD2 BGN	5.37e-04	185	90	4	87c416d14ca6255bee39b16e7571553e36ee3069
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CATSPERZ SOX4 MAP1B BGN	5.37e-04	185	90	4	35d39a1d04c871edcfb749653538dc5fd0054281
ToppCell	COPD-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	MAST4 MAP1B PLOD2 PHLDB2	5.37e-04	185	90	4	23579988036fc1925992c31919750f9b3fe9f790
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MAST4 ETFDH OMD BGN	5.37e-04	185	90	4	b57dae20c21f984edd2acee4344d86f033108ebf
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MAST4 ETFDH OMD BGN	5.37e-04	185	90	4	d3b054d203e575c1bb5455aa7a2e551a0957a760
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STRN3 MAP1B ATF4 TRAK1	5.37e-04	185	90	4	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 MAP1B RCAN2 BGN	5.37e-04	185	90	4	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK3 MAP1B CSMD1 RCAN2	5.48e-04	186	90	4	18fd311252299d6d30ddb32002ed069056108206
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac\|normal_Pleural_Fluid / Location, Cell class and cell subclass	STRN3 CHD3 ZNF251 PHLDB2	5.48e-04	186	90	4	3314def702fe6a5056d0dadbb3a587c5d1a16412
Disease	facial morphology	MCU MYO18A CSMD1 PHLDB2	2.14e-05	55	87	4	EFO_0004743
Disease	syndromic X-linked intellectual disability Najm type (implicated_via_orthology)	CSNK1A1L CSNK1A1	1.79e-04	7	87	2	DOID:0060807 (implicated_via_orthology)
Disease	phosphoglycerides measurement	TDRD15 ABCA1 MYO1H	3.89e-04	48	87	3	EFO_0022291
Disease	free cholesterol to total lipids in small HDL percentage	TDRD15 ABCA1 ETFDH	4.65e-04	51	87	3	EFO_0022285
Disease	total lipids in very large HDL measurement	TDRD15 ABCA1 ETFDH	9.91e-04	66	87	3	EFO_0022312
Disease	cholesterol in very large HDL measurement	TDRD15 ABCA1 ETFDH	1.13e-03	69	87	3	EFO_0022229
Disease	cyclic adenosine monophosphate measurement	MAST4 PXYLP1	1.14e-03	17	87	2	EFO_0010473
Disease	total lipids in large HDL	ABCA1 MYO1H ETFDH	1.38e-03	74	87	3	EFO_0022189
Disease	coagulation factor V measurement	MAST4 NME7	1.58e-03	20	87	2	EFO_0008087
Disease	free cholesterol in large HDL measurement	ABCA1 MYO1H ETFDH	1.67e-03	79	87	3	EFO_0022157
Disease	lipoprotein measurement, phospholipid measurement	TDRD15 ABCA1 MYO1H	2.05e-03	85	87	3	EFO_0004639, EFO_0004732
Disease	HDL cholesterol change measurement	ABCA1 ABCA10	2.27e-03	24	87	2	EFO_0007805
Disease	nighttime rest measurement	MYO18A CSMD1	2.27e-03	24	87	2	EFO_0007827
Disease	airway responsiveness measurement	CAPRIN2 CSMD1	2.27e-03	24	87	2	EFO_0006897
Disease	pulse pressure measurement	TDRD15 HIP1 ASAP2 MAP1B CDC16 ETFDH LCA5L MRPS27 OMD NME7 TRAK1	2.58e-03	1392	87	11	EFO_0005763
Disease	blood manganese measurement	OCRL CSMD1	2.88e-03	27	87	2	EFO_0007581

Protein segments in the cluster

Peptide	Gene	Start	Entry
VHYYIKLKDLRDQLK	TDG	286	Q13569
HFLTKELQRYIEGLK	CATSPERZ	176	Q9NTU4
GIYKKEEAHLLLKAF	CSMD1	3401	Q96PZ7
HLKNKFGRDYLLEIK	ABCA10	1426	Q8WWZ4
IAFHKLRKDYPAKIL	ADGRG4	2766	Q8IZF6
LGLLDDYLEVAKHFK	ATF4	31	P18848
KHPEYLKVGAKLLFR	GTPBP2	561	Q9BX10
FYARLKGLSEKHVKA	ABCA1	996	O95477
LKALKELGDFYLELH	ANKRD13C	216	Q8N6S4
RHDLVKLGFKYDNIL	AQR	1046	O60306
KKGIFYHRALLFKAL	ARMC3	791	Q5W041
LPKKYHVLRFLDKGE	AOC1	76	P19801
YKELLENEKKNFHLV	ASPM	1206	Q8IZT6
ALRKHKDLLGKRYIE	ESRP1	386	Q6NXG1
LHETQFRGKKLKLYF	RCAN2	71	Q14206
VHSKEKLRKGYLFLK	FRAS1	1181	Q86XX4
GLKRIITDKHFYFNK	HS3ST3B1	316	Q9Y662
YNILEGLEKLKHLDF	MAP1B	496	P46821
DRQYLLFFHKGAKKS	MCU	296	Q8NE86
GRLAFHGLLKKKYVF	NLRC3	401	Q7RTR2
DLHYSKAAKLFQLLK	EDRF1	1056	Q3B7T1
KKGVDLLQNLIKYFH	ASAP2	211	O43150
LEHRGRKISDLKKYA	FAM184B	276	Q9ULE4
GYLARQHFKKRKIQD	MYO18A	1201	Q92614
RKDDFKGLQHLYALV	BGN	106	P21810
KQLQLRHLKAIGKYE	LCA5L	176	O95447
GLKRIITDKHFYFNK	HS3ST3A1	331	Q9Y663
NKLFLIDFGLAKKYR	CSNK1A1L	151	Q8N752
NILKKGYLEIRKDHD	PLEKHM3	211	Q6ZWE6
LDYPKEALKLFIHNK	PLOD2	321	O00469
HLAKQLYKKFDLRAN	ETFDH	251	Q16134
NRYKIIKLLLLHGAD	ANKRD2	291	Q9GZV1
LGHVCRKLKKYAEAL	CDC16	451	Q13042
KLYHGLELAKKQLRA	CDC45	411	O75419
EGLCRKIIHYFNKGK	DOCK3	1291	Q8IZD9
FRVLNGYKIDHKLLL	CHD3	896	Q12873
RIHKPDLNYIAKFLK	COL6A5	2141	A8TX70
LKEKLDYHLETFRGK	GALNTL5	181	Q7Z4T8
LKLEDYKDRLKSGEH	CAPRIN2	141	Q6IMN6
KLGLDEYLDKLKHTE	FMNL2	346	Q96PY5
KKFGHKLNVSDLYKL	MARF1	906	Q9Y4F3
SRYFLELQHKLDKLL	MAST4	436	O15021
DRKLYKFLLLENVVH	IP6K1	201	Q92551
FLKRTKYDNLHLEDL	NME7	46	Q9Y5B8
GLQFLHEKKIIYRDL	PKN3	671	Q6P5Z2
NYLHDSLLKDKIFAK	OMD	196	Q99983
KLPQYLERFKALHSK	MRPS27	326	Q92552
LEYALKQERAKYHKL	STRN3	121	Q13033
KHLAEKKVKRVYLFG	SOX4	286	Q06945
LLAKLLEKKNYVHFA	TRIM33	326	Q9UPN9
KLYGDLKHLKTFDRG	SDHA	541	P31040
INEKIKVLLHAYGKR	TDRD15	1131	B5MCY1
QALARHFYIKKKDFG	SAMD9	1086	Q5K651
NKLFLIDFGLAKKYR	CSNK1A1	151	P48729
FNGLKILKRLYLHEN	SLITRK3	121	O94933
KERQKLGELRKKHYE	HIP1	996	O00291
NGQLLRDIYLKKHKL	PXYLP1	176	Q8TE99
HLGLLKAKLAKYRAQ	DRG2	26	P55039
KGRKKLRLFEYLHES	SPIC	106	Q8N5J4
LTEKKIKHLEQGYRE	NINL	431	Q9Y2I6
SLEERKKQHKEGLYL	PHLDB2	881	Q86SQ0
GLIKHILAKREKEYV	OCRL	221	Q01968
NYFHLDSLQKKLKDL	TRAK1	206	Q9UPV9
FDRGYIKKKLEHGLT	VPS50	371	Q96JG6
IEDSFHKLILKRYEK	ZNF595	91	Q8IYB9
LHLEFLYKENKAKEN	MINDY4	51	Q4G0A6
LLLHYLIKADKEGKF	RNASEH2B	96	Q5TBB1
EHLAKAEKYLKTGFL	NAPG	11	Q99747
EQFYRKLLNKHGIKT	RSL1D1	111	O76021
GKLRDFLLEHRKDYI	STX18	61	Q9P2W9
KLYKGARKILHELIF	UBR1	361	Q8IWV7
ENKLKKAAGYHLDLF	SLC4A5	861	Q9BY07
ARGLKYLHQEKKLLH	PBK	151	Q96KB5
VLLKHEVDKYRKLFQ	ZNF518A	61	Q6AHZ1
NILLDRKGHIKLAKF	TBCK	121	Q8TEA7
HRKYQELLKAIKGKD	PLEKHH1	86	Q9ULM0
IKRADILKHVIGDYK	NSMCE3	106	Q96MG7
GRKVLEKLYELKIHF	TOPAZ1	1381	Q8N9V7
KVLLRKYEKCGHENL	ZNF91	106	Q05481
LNDGSKRYFIHIKKI	ZNF251	651	Q9BRH9
LKGLYKTLKAHGFEE	ZZEF1	2356	O43149
LEYALKQERAKYHKL	STRN4	121	Q9NRL3
KNFELNLKTYHALLK	PTCD1	241	O75127
CGRKFIYKIKLDEHI	ZNF425	391	Q6IV72
FLKYIQERHGDSLKK	TCFL5	446	Q9UL49
AGYESLKKNEILHLK	WDR73	41	Q6P4I2
KKDLKEGLLLYHTEN	TSPAN9	116	O75954
KDRYLKHLRGQEHKY	TERF2IP	181	Q9NYB0
VFHKRYLKKIRDLGE	TYK2	891	P29597
KGFLEKNNDLLYRHL	MYO1H	526	Q8N1T3
KFDDFLIRHQIKYLG	MYO1H	606	Q8N1T3