Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphotransferase activity, phosphate group as acceptor	AK9 IP6K3 CASK	4.60e-05	41	34	3	GO:0016776
GeneOntologyMolecularFunction	sodium channel inhibitor activity	NEDD4L NEDD4	7.83e-05	8	34	2	GO:0019871
GeneOntologyMolecularFunction	nucleoside monophosphate kinase activity	AK9 CASK	6.96e-04	23	34	2	GO:0050145
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	AK9 IP6K3 TAF1L FGGY POLA1 CASK LRRK2	8.72e-04	938	34	7	GO:0016772
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor binding	GTF2E2 TAF1L	9.62e-04	27	34	2	GO:0001091
GeneOntologyMolecularFunction	kinase activity	AK9 IP6K3 TAF1L FGGY CASK LRRK2	1.65e-03	764	34	6	GO:0016301
GeneOntologyMolecularFunction	sodium channel regulator activity	NEDD4L NEDD4	2.55e-03	44	34	2	GO:0017080
GeneOntologyMolecularFunction	nucleobase-containing compound kinase activity	AK9 CASK	2.90e-03	47	34	2	GO:0019205
GeneOntologyMolecularFunction	ion channel inhibitor activity	NEDD4L NEDD4	3.02e-03	48	34	2	GO:0008200
GeneOntologyMolecularFunction	transmembrane transporter binding	USP10 NEDD4L LRRK2	3.09e-03	172	34	3	GO:0044325
GeneOntologyMolecularFunction	molecular function inhibitor activity	USP10 NEDD4L TAF1L LRRK2 NEDD4	3.17e-03	596	34	5	GO:0140678
GeneOntologyMolecularFunction	channel inhibitor activity	NEDD4L NEDD4	3.28e-03	50	34	2	GO:0016248
GeneOntologyMolecularFunction	transporter inhibitor activity	NEDD4L NEDD4	3.41e-03	51	34	2	GO:0141110
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor activity	GTF2E2 TAF1L	3.54e-03	52	34	2	GO:0016251
GeneOntologyMolecularFunction	structural constituent of ribosome	RPL22 RPL22L1 RPL35	3.68e-03	183	34	3	GO:0003735
GeneOntologyMolecularFunction	protein kinase A binding	AKAP7 LRRK2	4.38e-03	58	34	2	GO:0051018
GeneOntologyMolecularFunction	general transcription initiation factor binding	GTF2E2 TAF1L	5.31e-03	64	34	2	GO:0140296
GeneOntologyMolecularFunction	basal RNA polymerase II transcription machinery binding	GTF2E2 TAF1L	5.64e-03	66	34	2	GO:0001099
GeneOntologyMolecularFunction	basal transcription machinery binding	GTF2E2 TAF1L	5.64e-03	66	34	2	GO:0001098
GeneOntologyMolecularFunction	general transcription initiation factor activity	GTF2E2 TAF1L	5.98e-03	68	34	2	GO:0140223
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	IP6K3 TAF1L FGGY CASK LRRK2	6.59e-03	709	34	5	GO:0016773
GeneOntologyMolecularFunction	p53 binding	USP10 TAF1L	7.60e-03	77	34	2	GO:0002039
GeneOntologyMolecularFunction	transcription factor binding	DNAJA3 GTF2E2 PSIP1 TAF1L MED13	8.45e-03	753	34	5	GO:0008134
GeneOntologyBiologicalProcess	vesicle-mediated transport in synapse	P2RX1 NEDD4L SYNJ1 CASK LRRK2 NEDD4	1.05e-05	321	33	6	GO:0099003
GeneOntologyBiologicalProcess	regulation of postsynaptic neurotransmitter receptor internalization	NEDD4L SYNJ1 NEDD4	3.28e-05	39	33	3	GO:0099149
GeneOntologyBiologicalProcess	synaptic vesicle exocytosis	P2RX1 SYNJ1 CASK LRRK2	4.59e-05	125	33	4	GO:0016079
GeneOntologyBiologicalProcess	postsynaptic endocytosis	NEDD4L SYNJ1 NEDD4	7.37e-05	51	33	3	GO:0140239
GeneOntologyBiologicalProcess	postsynaptic neurotransmitter receptor internalization	NEDD4L SYNJ1 NEDD4	7.37e-05	51	33	3	GO:0098884
GeneOntologyBiologicalProcess	neurotransmitter receptor internalization	NEDD4L SYNJ1 NEDD4	1.08e-04	58	33	3	GO:0099590
GeneOntologyBiologicalProcess	regulation protein catabolic process at postsynapse	NEDD4L NEDD4	1.11e-04	10	33	2	GO:0140252
GeneOntologyBiologicalProcess	regulation of postsynaptic membrane neurotransmitter receptor levels	EPS8 NEDD4L SYNJ1 NEDD4	1.32e-04	164	33	4	GO:0099072
GeneOntologyBiologicalProcess	regulation of synaptic vesicle exocytosis	P2RX1 CASK LRRK2	1.32e-04	62	33	3	GO:2000300
GeneOntologyBiologicalProcess	regulation of potassium ion transmembrane transporter activity	NEDD4L AKAP7 NEDD4	1.39e-04	63	33	3	GO:1901016
GeneOntologyBiologicalProcess	neuromuscular junction development	DNAJA3 LRRK2 NEDD4	1.74e-04	68	33	3	GO:0007528
GeneOntologyBiologicalProcess	regulation protein catabolic process at synapse	NEDD4L NEDD4	2.23e-04	14	33	2	GO:0140250
GeneOntologyBiologicalProcess	signal release from synapse	P2RX1 SYNJ1 CASK LRRK2	2.56e-04	195	33	4	GO:0099643
GeneOntologyBiologicalProcess	neurotransmitter secretion	P2RX1 SYNJ1 CASK LRRK2	2.56e-04	195	33	4	GO:0007269
GeneOntologyBiologicalProcess	dendrite morphogenesis	NEDD4L CASK LRRK2 NEDD4	2.71e-04	198	33	4	GO:0048813
GeneOntologyBiologicalProcess	negative regulation of sodium ion transmembrane transporter activity	NEDD4L NEDD4	2.94e-04	16	33	2	GO:2000650
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection organization	EPS8 INTU NEDD4L NRDC CASK LRRK2 NEDD4	3.20e-04	846	33	7	GO:0120035
GeneOntologyBiologicalProcess	positive regulation of synaptic vesicle recycling	SYNJ1 LRRK2	3.33e-04	17	33	2	GO:1903423
GeneOntologyBiologicalProcess	negative regulation of sodium ion transmembrane transport	NEDD4L NEDD4	3.33e-04	17	33	2	GO:1902306
GeneOntologyBiologicalProcess	regulation of cell projection organization	EPS8 INTU NEDD4L NRDC CASK LRRK2 NEDD4	3.61e-04	863	33	7	GO:0031344
GeneOntologyBiologicalProcess	positive regulation of proteolysis	DNAJA3 P2RX1 NRDC NLRC4 LRRK2	3.61e-04	390	33	5	GO:0045862
GeneOntologyBiologicalProcess	positive regulation of protein catabolic process	NEDD4L NRDC LRRK2 NEDD4	4.63e-04	228	33	4	GO:0045732
GeneOntologyBiologicalProcess	regulation of receptor internalization	NEDD4L SYNJ1 NEDD4	4.67e-04	95	33	3	GO:0002090
GeneOntologyBiologicalProcess	regulation of potassium ion transmembrane transport	NEDD4L AKAP7 NEDD4	4.97e-04	97	33	3	GO:1901379
GeneOntologyBiologicalProcess	negative regulation of sodium ion transport	NEDD4L NEDD4	5.62e-04	22	33	2	GO:0010766
GeneOntologyBiologicalProcess	regulation of vesicle-mediated transport	P2RX1 NEDD4L SYNJ1 CASK LRRK2 NEDD4	5.87e-04	667	33	6	GO:0060627
GeneOntologyBiologicalProcess	regulation of dendrite morphogenesis	NEDD4L CASK NEDD4	5.92e-04	103	33	3	GO:0048814
GeneOntologyBiologicalProcess	regulation of protein kinase A signaling	AKAP7 LRRK2	6.15e-04	23	33	2	GO:0010738
GeneOntologyBiologicalProcess	neurotransmitter transport	P2RX1 SYNJ1 CASK LRRK2	7.46e-04	259	33	4	GO:0006836
GeneOntologyBiologicalProcess	synaptic vesicle cycle	P2RX1 SYNJ1 CASK LRRK2	8.02e-04	264	33	4	GO:0099504
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transport	P2RX1 NEDD4L AKAP7 CASK	8.24e-04	266	33	4	GO:0043270
GeneOntologyBiologicalProcess	regulation of neurotransmitter secretion	P2RX1 CASK LRRK2	8.79e-04	118	33	3	GO:0046928
GeneOntologyBiologicalProcess	regulation of potassium ion transport	NEDD4L AKAP7 NEDD4	9.45e-04	121	33	3	GO:0043266
GeneOntologyBiologicalProcess	protein-containing complex localization	INTU NEDD4L SYNJ1 NEDD4	9.71e-04	278	33	4	GO:0031503
GeneOntologyBiologicalProcess	negative regulation of keratinocyte proliferation	INTU CASK	9.81e-04	29	33	2	GO:0010839
GeneOntologyBiologicalProcess	regulation of metal ion transport	P2RX1 NEDD4L AKAP7 CASK NEDD4	1.04e-03	493	33	5	GO:0010959
GeneOntologyBiologicalProcess	positive regulation of dendrite extension	CPNE6 NEDD4L	1.12e-03	31	33	2	GO:1903861
GeneOntologyBiologicalProcess	regulated exocytosis	P2RX1 SYNJ1 CASK LRRK2	1.15e-03	291	33	4	GO:0045055
GeneOntologyBiologicalProcess	regulation of cell morphogenesis	EPS8 CPNE6 NEDD4L CASK	1.32e-03	302	33	4	GO:0022604
GeneOntologyBiologicalProcess	positive regulation of calcium ion import	P2RX1 CASK	1.35e-03	34	33	2	GO:0090280
GeneOntologyBiologicalProcess	positive regulation of transport	P2RX1 NEDD4L SYNJ1 AKAP7 CASK LRRK2 NEDD4	1.37e-03	1081	33	7	GO:0051050
GeneOntologyBiologicalProcess	regulation of dendrite extension	CPNE6 NEDD4L	1.43e-03	35	33	2	GO:1903859
GeneOntologyBiologicalProcess	regulation of anatomical structure morphogenesis	EPS8 CPNE6 NEDD4L NRDC CASK LRRK2 NEDD4	1.44e-03	1090	33	7	GO:0022603
GeneOntologyBiologicalProcess	regulation of neurotransmitter transport	P2RX1 CASK LRRK2	1.47e-03	141	33	3	GO:0051588
GeneOntologyBiologicalProcess	postsynapse organization	DNAJA3 CPNE6 CASK LRRK2	1.50e-03	313	33	4	GO:0099173
GeneOntologyBiologicalProcess	neuron projection morphogenesis	CPNE6 NEDD4L NRDC CASK LRRK2 NEDD4	1.53e-03	802	33	6	GO:0048812
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	CPNE6 NEDD4L NRDC CASK LRRK2 NEDD4	1.70e-03	819	33	6	GO:0120039
GeneOntologyBiologicalProcess	regulation of dendrite development	NEDD4L CASK NEDD4	1.75e-03	150	33	3	GO:0050773
GeneOntologyBiologicalProcess	cell projection morphogenesis	CPNE6 NEDD4L NRDC CASK LRRK2 NEDD4	1.78e-03	826	33	6	GO:0048858
GeneOntologyBiologicalProcess	regulation of membrane potential	P2RX1 NEDD4L AKAP7 LRRK2 NEDD4	1.82e-03	559	33	5	GO:0042391
GeneOntologyBiologicalProcess	positive regulation of cysteine-type endopeptidase activity	DNAJA3 P2RX1 NLRC4	1.82e-03	152	33	3	GO:2001056
GeneOntologyBiologicalProcess	regulation of endopeptidase activity	DNAJA3 P2RX1 NRDC NLRC4	1.87e-03	332	33	4	GO:0052548
GeneOntologyBiologicalProcess	dendrite development	NEDD4L CASK LRRK2 NEDD4	1.93e-03	335	33	4	GO:0016358
GeneOntologyBiologicalProcess	regulation of membrane repolarization	NEDD4L AKAP7	1.96e-03	41	33	2	GO:0060306
GeneOntologyBiologicalProcess	regulation of receptor-mediated endocytosis	NEDD4L SYNJ1 NEDD4	1.96e-03	156	33	3	GO:0048259
GeneOntologyBiologicalProcess	regulation of monoatomic ion transport	P2RX1 NEDD4L AKAP7 CASK NEDD4	2.09e-03	577	33	5	GO:0043269
GeneOntologyBiologicalProcess	regulation of synaptic vesicle recycling	SYNJ1 LRRK2	2.25e-03	44	33	2	GO:1903421
GeneOntologyBiologicalProcess	regulation of regulated secretory pathway	P2RX1 CASK LRRK2	2.30e-03	165	33	3	GO:1903305
GeneOntologyBiologicalProcess	positive regulation of neurogenesis	NRDC SYNJ1 ELL3 CASK	2.36e-03	354	33	4	GO:0050769
GeneOntologyBiologicalProcess	cell morphogenesis	EPS8 CPNE6 NEDD4L NRDC CASK LRRK2 NEDD4	2.42e-03	1194	33	7	GO:0000902
GeneOntologyBiologicalProcess	dendrite extension	CPNE6 NEDD4L	2.46e-03	46	33	2	GO:0097484
GeneOntologyBiologicalProcess	cytoplasmic translation	RPL22 RPL22L1 RPL35	2.59e-03	172	33	3	GO:0002181
GeneOntologyBiologicalProcess	positive regulation of cation transmembrane transport	P2RX1 NEDD4L AKAP7	2.67e-03	174	33	3	GO:1904064
GeneOntologyBiologicalProcess	protein kinase A signaling	AKAP7 LRRK2	2.67e-03	48	33	2	GO:0010737
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	USP10 POLA1	2.67e-03	48	33	2	GO:0000731
GeneOntologyBiologicalProcess	regulation of neuron projection development	NEDD4L NRDC CASK LRRK2 NEDD4	2.70e-03	612	33	5	GO:0010975
GeneOntologyBiologicalProcess	translation at presynapse	RPL22 RPL35	2.79e-03	49	33	2	GO:0140236
GeneOntologyBiologicalProcess	positive regulation of endopeptidase activity	DNAJA3 P2RX1 NLRC4	2.81e-03	177	33	3	GO:0010950
GeneOntologyBiologicalProcess	translation at synapse	RPL22 RPL35	2.90e-03	50	33	2	GO:0140241
GeneOntologyBiologicalProcess	translation at postsynapse	RPL22 RPL35	2.90e-03	50	33	2	GO:0140242
GeneOntologyBiologicalProcess	receptor internalization	NEDD4L SYNJ1 NEDD4	3.03e-03	182	33	3	GO:0031623
GeneOntologyBiologicalProcess	regulation of monoatomic cation transmembrane transport	P2RX1 NEDD4L AKAP7 NEDD4	3.04e-03	380	33	4	GO:1904062
GeneOntologyBiologicalProcess	inositol phosphate metabolic process	IP6K3 SYNJ1	3.13e-03	52	33	2	GO:0043647
GeneOntologyBiologicalProcess	negative regulation of organelle assembly	USP10 LRRK2	3.13e-03	52	33	2	GO:1902116
GeneOntologyBiologicalProcess	transcription initiation at RNA polymerase II promoter	GTF2E2 TAF1L MED13	3.23e-03	186	33	3	GO:0006367
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	P2RX1 SYNJ1 AKAP7 CASK LRRK2 NEDD4	3.24e-03	931	33	6	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	P2RX1 SYNJ1 AKAP7 CASK LRRK2 NEDD4	3.24e-03	931	33	6	GO:0007268
GeneOntologyBiologicalProcess	regulation of endocytosis	NEDD4L SYNJ1 LRRK2 NEDD4	3.31e-03	389	33	4	GO:0030100
GeneOntologyBiologicalProcess	synaptic vesicle transport	SYNJ1 LRRK2	3.37e-03	54	33	2	GO:0048489
GeneOntologyBiologicalProcess	protein monoubiquitination	NEDD4L NEDD4	3.37e-03	54	33	2	GO:0006513
GeneOntologyBiologicalProcess	trans-synaptic signaling	P2RX1 SYNJ1 AKAP7 CASK LRRK2 NEDD4	3.38e-03	939	33	6	GO:0099537
GeneOntologyBiologicalProcess	positive regulation of peptidase activity	DNAJA3 P2RX1 NLRC4	3.53e-03	192	33	3	GO:0010952
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transmembrane transport	P2RX1 NEDD4L AKAP7	3.53e-03	192	33	3	GO:0034767
GeneOntologyBiologicalProcess	positive regulation of cation channel activity	NEDD4L AKAP7	3.62e-03	56	33	2	GO:2001259
GeneOntologyBiologicalProcess	membrane repolarization	NEDD4L AKAP7	3.62e-03	56	33	2	GO:0086009
GeneOntologyBiologicalProcess	regulation of keratinocyte proliferation	INTU CASK	3.62e-03	56	33	2	GO:0010837
GeneOntologyBiologicalProcess	regulation of sodium ion transmembrane transporter activity	NEDD4L NEDD4	3.75e-03	57	33	2	GO:2000649
GeneOntologyBiologicalProcess	modulation of chemical synaptic transmission	P2RX1 AKAP7 CASK LRRK2 NEDD4	3.80e-03	663	33	5	GO:0050804
GeneOntologyCellularComponent	glutamatergic synapse	RPL22 EPS8 P2RX1 NEDD4L SYNJ1 LRRK2 NEDD4	2.38e-04	817	33	7	GO:0098978
GeneOntologyCellularComponent	nuclear DNA-directed RNA polymerase complex	GTF2E2 TAF1L POLA1	7.46e-04	113	33	3	GO:0055029
GeneOntologyCellularComponent	ribosome	RPL22 USP10 RPL22L1 RPL35	7.96e-04	267	33	4	GO:0005840
GeneOntologyCellularComponent	DNA-directed RNA polymerase complex	GTF2E2 TAF1L POLA1	8.05e-04	116	33	3	GO:0000428
GeneOntologyCellularComponent	RNA polymerase complex	GTF2E2 TAF1L POLA1	8.66e-04	119	33	3	GO:0030880
GeneOntologyCellularComponent	postsynapse	RPL22 DNAJA3 EPS8 RPL35 P2RX1 LRRK2 NEDD4	8.93e-04	1018	33	7	GO:0098794
GeneOntologyCellularComponent	cytosolic ribosome	RPL22 USP10 RPL35	9.76e-04	124	33	3	GO:0022626
GeneOntologyCellularComponent	transferase complex, transferring phosphorus-containing groups	GTF2E2 TAF1L POLA1 MED13	1.84e-03	335	33	4	GO:0061695
GeneOntologyCellularComponent	presynapse	RPL22 RPL35 P2RX1 SYNJ1 CASK LRRK2	2.37e-03	886	33	6	GO:0098793
GeneOntologyCellularComponent	nuclear periphery	PSIP1 POLA1 CASK	2.45e-03	171	33	3	GO:0034399
GeneOntologyCellularComponent	transcription factor TFIID complex	GTF2E2 TAF1L	2.50e-03	47	33	2	GO:0005669
MousePheno	small exoccipital bone	PSIP1 NEDD4	3.58e-05	5	27	2	MP:0004445
Domain	Ribosomal_L22e	RPL22 RPL22L1	3.41e-06	2	35	2	IPR002671
Domain	Ribosomal_L22e	RPL22 RPL22L1	3.41e-06	2	35	2	PF01776
Domain	HECT	NEDD4L NEDD4	1.16e-03	27	35	2	PF00632
Domain	HECTc	NEDD4L NEDD4	1.16e-03	27	35	2	SM00119
Domain	HECT_dom	NEDD4L NEDD4	1.16e-03	27	35	2	IPR000569
Domain	HECT	NEDD4L NEDD4	1.16e-03	27	35	2	PS50237
Domain	C2	CPNE6 NEDD4L NEDD4	1.87e-03	131	35	3	PF00168
Domain	C2	CPNE6 NEDD4L NEDD4	2.13e-03	137	35	3	SM00239
Domain	C2	CPNE6 NEDD4L NEDD4	2.36e-03	142	35	3	PS50004
Domain	-	CPNE6 NEDD4L NEDD4	2.65e-03	148	35	3	2.60.40.150
Domain	WW	NEDD4L NEDD4	3.50e-03	47	35	2	PF00397
Domain	C2_dom	CPNE6 NEDD4L NEDD4	3.54e-03	164	35	3	IPR000008
Domain	WW	NEDD4L NEDD4	3.65e-03	48	35	2	SM00456
Domain	WW_DOMAIN_2	NEDD4L NEDD4	4.11e-03	51	35	2	PS50020
Domain	WW_DOMAIN_1	NEDD4L NEDD4	4.11e-03	51	35	2	PS01159
Domain	WW_dom	NEDD4L NEDD4	4.27e-03	52	35	2	IPR001202
Domain	-	ANKRD31 ANKRD12 LRRK2	1.11e-02	248	35	3	1.25.40.20
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	RPL22 DNAJA3 USP10 GTF2E2 RPL22L1 RPL35 NEDD4L PSIP1 NRDC POLA1	8.71e-07	1415	35	10	28515276
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RPL22 EPS8 USP10 GTF2E2 CPNE6 RPL35 NEDD4L NRDC SYNJ1 CASK	9.65e-07	1431	35	10	37142655
Pubmed	The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1.	RPL22 RPL22L1	9.84e-07	2	35	2	23990801
Pubmed	Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na(+) channel regulation.	NEDD4L NEDD4	9.84e-07	2	35	2	11502596
Pubmed	RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance.	RPL22 RPL22L1	9.84e-07	2	35	2	31581233
Pubmed	Nedd4 and Nedd4-2: ubiquitin ligases at work in the neuron.	NEDD4L NEDD4	9.84e-07	2	35	2	23262292
Pubmed	Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2.	NEDD4L NEDD4	9.84e-07	2	35	2	37962894
Pubmed	Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson's disease.	SYNJ1 LRRK2	9.84e-07	2	35	2	27794539
Pubmed	Down-regulating destruction: phosphorylation regulates the E3 ubiquitin ligase Nedd4-2.	NEDD4L NEDD4	9.84e-07	2	35	2	19602703
Pubmed	A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel.	NEDD4L NEDD4	9.84e-07	2	35	2	11149908
Pubmed	Dietary sodium modulates nephropathy in Nedd4-2-deficient mice.	NEDD4L NEDD4	9.84e-07	2	35	2	31802037
Pubmed	Alternative splicing determines the domain structure of WWP1, a Nedd4 family protein.	NEDD4L NEDD4	2.95e-06	3	35	2	11779188
Pubmed	Regulation of Nedd4-2 self-ubiquitination and stability by a PY motif located within its HECT-domain.	NEDD4L NEDD4	2.95e-06	3	35	2	18498246
Pubmed	Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.	NEDD4L NEDD4	2.95e-06	3	35	2	21852580
Pubmed	The high-affinity choline transporter CHT1 is regulated by the ubiquitin ligase Nedd4-2.	NEDD4L NEDD4	2.95e-06	3	35	2	22361880
Pubmed	Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination.	NEDD4L NEDD4	2.95e-06	3	35	2	15217910
Pubmed	Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking in Ventral Midbrain Neurons.	SYNJ1 LRRK2	2.95e-06	3	35	2	29054882
Pubmed	Cell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval development.	EPS8 CASK	2.95e-06	3	35	2	16688213
Pubmed	Characterization of the interactions between Nedd4-2, ENaC, and sgk-1 using surface plasmon resonance.	NEDD4L NEDD4	2.95e-06	3	35	2	12729930
Pubmed	Nedd4-2-mediated ubiquitination facilitates processing of surfactant protein-C.	NEDD4L NEDD4	2.95e-06	3	35	2	19423771
Pubmed	Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein.	NEDD4L NEDD4	2.95e-06	3	35	2	12050153
Pubmed	Unbiased proteomic screening identifies a novel role for the E3 ubiquitin ligase Nedd4-2 in translational suppression during ER stress.	RPL22 NEDD4L	2.95e-06	3	35	2	33064840
Pubmed	Interaction of serum- and glucocorticoid regulated kinase 1 (SGK1) with the WW-domains of Nedd4-2 is required for epithelial sodium channel regulation.	NEDD4L NEDD4	2.95e-06	3	35	2	20730100
Pubmed	Nedd4-2 but not Nedd4-1 is critical for protein kinase C-regulated ubiquitination, expression, and transport activity of human organic anion transporter 1.	NEDD4L NEDD4	2.95e-06	3	35	2	26823285
Pubmed	Mutations in TNK2 in severe autosomal recessive infantile onset epilepsy.	NEDD4L NEDD4	2.95e-06	3	35	2	23686771
Pubmed	Nedd4-2 does not regulate wt-CFTR in human airway epithelial cells.	USP10 NEDD4L	2.95e-06	3	35	2	22904170
Pubmed	14-3-3 proteins modulate the expression of epithelial Na+ channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase.	NEDD4L NEDD4	2.95e-06	3	35	2	15677482
Pubmed	Bone Marrow Stem Cell-Exo-Derived TSG-6 Attenuates 1-Methyl-4-Phenylpyridinium+-Induced Neurotoxicity via the STAT3/miR-7/NEDD4/LRRK2 Axis.	LRRK2 NEDD4	2.95e-06	3	35	2	35773961
Pubmed	The Ubiquitin Ligase Itch and Ubiquitination Regulate BFRF1-Mediated Nuclear Envelope Modification for Epstein-Barr Virus Maturation.	NEDD4L NEDD4	5.90e-06	4	35	2	27466427
Pubmed	SGK1/Nedd4-2 signaling pathway regulates the activity of human organic anion transporters 3.	NEDD4L NEDD4	5.90e-06	4	35	2	28608480
Pubmed	GRK2 interacts with and phosphorylates Nedd4 and Nedd4-2.	NEDD4L NEDD4	5.90e-06	4	35	2	17544362
Pubmed	The ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1.	NEDD4L NEDD4	5.90e-06	4	35	2	20026598
Pubmed	C2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms.	NEDD4L NEDD4	5.90e-06	4	35	2	31357244
Pubmed	Kir5.1 regulates Nedd4-2-mediated ubiquitination of Kir4.1 in distal nephron.	NEDD4L NEDD4	5.90e-06	4	35	2	29897283
Pubmed	NEDD4-2 associates with gamma(c) and regulates its degradation rate.	NEDD4L NEDD4	5.90e-06	4	35	2	19615332
Pubmed	Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels.	NEDD4L NEDD4	5.90e-06	4	35	2	22024150
Pubmed	Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing.	RPL22 RPL22L1	5.90e-06	4	35	2	28076796
Pubmed	Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel.	NEDD4L NEDD4	5.90e-06	4	35	2	11696533
Pubmed	Nedd4-2-dependent ubiquitylation and regulation of the cardiac potassium channel hERG1.	NEDD4L NEDD4	5.90e-06	4	35	2	21463633
Pubmed	Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins.	NEDD4L NEDD4	9.82e-06	5	35	2	15548568
Pubmed	Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.	NEDD4L NEDD4	9.82e-06	5	35	2	25157163
Pubmed	Oligomerization of the HECT ubiquitin ligase NEDD4-2/NEDD4L is essential for polyubiquitin chain assembly.	NEDD4L NEDD4	9.82e-06	5	35	2	30287686
Pubmed	An obligatory heterodimer of 14-3-3beta and 14-3-3epsilon is required for aldosterone regulation of the epithelial sodium channel.	NEDD4L NEDD4	9.82e-06	5	35	2	18687683
Pubmed	Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis.	NEDD4L NEDD4	9.82e-06	5	35	2	27793840
Pubmed	The Nedd4-like ubiquitin E3 ligases target angiomotin/p130 to ubiquitin-dependent degradation.	NEDD4L NEDD4	9.82e-06	5	35	2	22385262
Pubmed	Ubiquitin-specific protease 2-45 (Usp2-45) binds to epithelial Na+ channel (ENaC)-ubiquitylating enzyme Nedd4-2.	NEDD4L NEDD4	9.82e-06	5	35	2	21478478
Pubmed	NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor.	NEDD4L NEDD4	9.82e-06	5	35	2	31867777
Pubmed	A Nedd4 E3 Ubiquitin Ligase Pathway Inhibits Robo1 Repulsion and Promotes Commissural Axon Guidance across the Midline.	NEDD4L NEDD4	9.82e-06	5	35	2	36002265
Pubmed	The ESCRT pathway and HIV-1 budding.	NEDD4L NEDD4	9.82e-06	5	35	2	19143627
Pubmed	Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons.	NEDD4L NEDD4	9.82e-06	5	35	2	19706893
Pubmed	Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway.	NEDD4L NEDD4	9.82e-06	5	35	2	19617352
Pubmed	Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response.	NEDD4L NEDD4	9.82e-06	5	35	2	25631046
Pubmed	The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels.	NEDD4L NEDD4	9.82e-06	5	35	2	18577513
Pubmed	The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family.	NEDD4L NEDD4	9.82e-06	5	35	2	17289006
Pubmed	N4WBP5A (Ndfip2), a Nedd4-interacting protein, localizes to multivesicular bodies and the Golgi, and has a potential role in protein trafficking.	NEDD4L NEDD4	1.47e-05	6	35	2	15252135
Pubmed	Lysosomal-associated protein transmembrane 5 ameliorates non-alcoholic steatohepatitis by promoting the degradation of CDC42 in mice.	NEDD4L NEDD4	1.47e-05	6	35	2	37156795
Pubmed	Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).	NEDD4L NEDD4	1.47e-05	6	35	2	27445338
Pubmed	Cell survival through Trk neurotrophin receptors is differentially regulated by ubiquitination.	NEDD4L NEDD4	1.47e-05	6	35	2	16701206
Pubmed	Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis.	RPL22 RPL22L1	1.47e-05	6	35	2	35046107
Pubmed	Regulation of Itch and Nedd4 E3 Ligase Activity and Degradation by LRAD3.	NEDD4L NEDD4	1.47e-05	6	35	2	26854353
Pubmed	β-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.	NEDD4L NEDD4	1.47e-05	6	35	2	29964046
Pubmed	N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein.	NEDD4L NEDD4	1.47e-05	6	35	2	11748237
Pubmed	A cell-based high-throughput screening method based on a ubiquitin-reference technique for identifying modulators of E3 ligases.	NEDD4L NEDD4	2.06e-05	7	35	2	30587574
Pubmed	Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases.	NEDD4L NEDD4	2.06e-05	7	35	2	11046148
Pubmed	Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming.	NEDD4L NEDD4	2.06e-05	7	35	2	23644597
Pubmed	Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes.	NEDD4L NEDD4	2.06e-05	7	35	2	20051513
Pubmed	HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK.	NEDD4L NEDD4	2.06e-05	7	35	2	20086093
Pubmed	Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein.	NEDD4L NEDD4	2.06e-05	7	35	2	24831002
Pubmed	The ubiquitin-protein ligases Nedd4 and Nedd4-2 show similar ubiquitin-conjugating enzyme specificities.	NEDD4L NEDD4	2.06e-05	7	35	2	16337426
Pubmed	The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel.	NEDD4L NEDD4	2.74e-05	8	35	2	11244092
Pubmed	Ndfip1 expression in developing neurons indicates a role for protein ubiquitination by Nedd4 E3 ligases during cortical development.	NEDD4L NEDD4	2.74e-05	8	35	2	24036464
Pubmed	Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain.	NEDD4L NEDD4	2.74e-05	8	35	2	17719543
Pubmed	Functional regulation of the epithelial Na+ channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2.	NEDD4L NEDD4	3.53e-05	9	35	2	18981174
Pubmed	NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.	NEDD4L NEDD4	3.53e-05	9	35	2	15496141
Pubmed	Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog.	NEDD4L NEDD4	4.40e-05	10	35	2	25092867
Pubmed	Recognition sequences for the GYF domain reveal a possible spliceosomal function of CD2BP2.	SYNJ1 NEDD4	4.40e-05	10	35	2	15105431
Pubmed	Interactomic analysis of REST/NRSF and implications of its functional links with the transcription suppressor TRIM28 during neuronal differentiation.	RPL22 RPL35 PSIP1 SYNJ1	5.32e-05	205	35	4	27976729
Pubmed	USP11 augments TGFβ signalling by deubiquitylating ALK5.	NEDD4L NEDD4	5.38e-05	11	35	2	22773947
Pubmed	Respiratory distress and perinatal lethality in Nedd4-2-deficient mice.	NEDD4L NEDD4	5.38e-05	11	35	2	21505443
Pubmed	Synaptic vesicle trafficking and Parkinson's disease.	SYNJ1 LRRK2	5.38e-05	11	35	2	21563316
Pubmed	Dysregulated Inflammatory Signaling upon Charcot-Marie-Tooth Type 1C Mutation of SIMPLE Protein.	NEDD4L NEDD4	5.38e-05	11	35	2	25963657
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	USP10 RPL22L1 NEDD4L NRDC POLA1 AKAP7 CASK	5.46e-05	1005	35	7	19615732
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	NEDD4L NEDD4	7.62e-05	13	35	2	15123669
Pubmed	Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch.	NEDD4L NEDD4	7.62e-05	13	35	2	23146885
Pubmed	Mammalian α arrestins link activated seven transmembrane receptors to Nedd4 family e3 ubiquitin ligases and interact with β arrestins.	NEDD4L NEDD4	1.02e-04	15	35	2	23236378
Pubmed	Reverse two-hybrid screening to analyze protein-protein interaction of HIV-1 viral and cellular proteins.	PSIP1 NEDD4	1.02e-04	15	35	2	19020832
Pubmed	SYT14L, especially its C2 domain, is involved in regulating melanocyte differentiation.	CPNE6 NEDD4L	1.02e-04	15	35	2	23999003
Pubmed	Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases.	NEDD4L NEDD4	1.17e-04	16	35	2	21920314
Pubmed	RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling.	NEDD4L NEDD4	1.33e-04	17	35	2	28292929
Pubmed	A strategy for modulation of enzymes in the ubiquitin system.	USP10 NEDD4	1.33e-04	17	35	2	23287719
Pubmed	Wrapping up the bad news: HIV assembly and release.	NEDD4L NEDD4	1.49e-04	18	35	2	23305486
Pubmed	Circular RNA FOXP1 promotes tumor progression and Warburg effect in gallbladder cancer by regulating PKLR expression.	RPL22 RPL35 NLRC4	1.50e-04	102	35	3	31623628
Pubmed	SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.	NEDD4L NEDD4	1.66e-04	19	35	2	21572392
Pubmed	Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.	NEDD4L NEDD4	2.04e-04	21	35	2	37005481
Pubmed	ARRDC1 and ARRDC3 act as tumor suppressors in renal cell carcinoma by facilitating YAP1 degradation.	NEDD4L NEDD4	2.04e-04	21	35	2	29416926
Pubmed	TIM-1 Ubiquitination Mediates Dengue Virus Entry.	DNAJA3 NEDD4L	2.46e-04	23	35	2	29742433
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	DNAJA3 CPNE6 FGGY KLB	2.70e-04	313	35	4	20800603
Pubmed	Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.	NEDD4L NEDD4	2.91e-04	25	35	2	23873930
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	USP10 GTF2E2 RPL35 PSIP1 SYNJ1 DEPDC1B	3.08e-04	934	35	6	33916271
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	NEDD4L NEDD4	3.15e-04	26	35	2	26949039
Interaction	RASL11B interactions	NEDD4L LRRK2 NEDD4	4.56e-06	19	35	3	int:RASL11B
Interaction	CLIC2 interactions	RPL35 NEDD4L NEDD4	5.36e-06	20	35	3	int:CLIC2
Interaction	PRRG3 interactions	NEDD4L NEDD4	2.92e-05	5	35	2	int:PRRG3
Interaction	CYYR1 interactions	NEDD4L NEDD4	8.15e-05	8	35	2	int:CYYR1
Interaction	KCTD13 interactions	RPL22 EPS8 USP10 GTF2E2 CPNE6 RPL35 NEDD4L NRDC SYNJ1 CASK	9.01e-05	1394	35	10	int:KCTD13
Interaction	FGFR1 interactions	RPL22 DNAJA3 RPL22L1 SYNJ1 CASK KLB NEDD4	9.03e-05	632	35	7	int:FGFR1
Interaction	CAMK1D interactions	NEDD4L LRRK2 NEDD4	1.12e-04	54	35	3	int:CAMK1D
Interaction	ULK1 interactions	USP10 NEDD4L PSIP1 NEDD4	1.19e-04	147	35	4	int:ULK1
Interaction	EFTUD2 interactions	RPL22 DNAJA3 USP10 GTF2E2 RPL22L1 RPL35 NEDD4L PSIP1 POLA1 MED13	1.24e-04	1449	35	10	int:EFTUD2
Interaction	MS4A10 interactions	NEDD4L NEDD4	1.31e-04	10	35	2	int:MS4A10
Interaction	PRRG2 interactions	NEDD4L NEDD4	1.31e-04	10	35	2	int:PRRG2
Interaction	JHY interactions	LRRK2 NEDD4	1.31e-04	10	35	2	int:JHY
Interaction	SCN10A interactions	NEDD4L NEDD4	1.60e-04	11	35	2	int:SCN10A
Interaction	TMEM252 interactions	NEDD4L NEDD4	1.60e-04	11	35	2	int:TMEM252
Interaction	ILDR1 interactions	NEDD4L NEDD4	1.60e-04	11	35	2	int:ILDR1
Interaction	SCNN1A interactions	USP10 NEDD4L NEDD4	1.86e-04	64	35	3	int:SCNN1A
Interaction	FGF21 interactions	KLB NEDD4	1.91e-04	12	35	2	int:FGF21
Interaction	RPSA interactions	RPL22 RPL22L1 RPL35 NLRC4 LRRK2 NEDD4	2.51e-04	522	35	6	int:RPSA
Interaction	MOB3A interactions	NEDD4L NEDD4	2.63e-04	14	35	2	int:MOB3A
Interaction	DGCR2 interactions	DNAJA3 NEDD4L DEPDC1B NEDD4	2.65e-04	181	35	4	int:DGCR2
Interaction	AICDA interactions	USP10 NEDD4L NEDD4	2.75e-04	73	35	3	int:AICDA
Interaction	PRRG1 interactions	NEDD4L NEDD4	3.03e-04	15	35	2	int:PRRG1
Interaction	FBP1 interactions	RPL22 RPL35 NEDD4L PSIP1 NEDD4	3.16e-04	348	35	5	int:FBP1
Interaction	HDGFL2 interactions	RPL22 GTF2E2 PSIP1 LRRK2	3.45e-04	194	35	4	int:HDGFL2
Interaction	PRR16 interactions	NEDD4L NEDD4	3.46e-04	16	35	2	int:PRR16
Interaction	SCN3A interactions	NEDD4L NEDD4	3.46e-04	16	35	2	int:SCN3A
Interaction	SUSD6 interactions	NEDD4L NEDD4	3.46e-04	16	35	2	int:SUSD6
Interaction	EFCAB11 interactions	SFI1 CASK	3.46e-04	16	35	2	int:EFCAB11
Interaction	CUEDC1 interactions	NEDD4L LRRK2 NEDD4	3.87e-04	82	35	3	int:CUEDC1
Interaction	TMEM92 interactions	NEDD4L NEDD4	3.92e-04	17	35	2	int:TMEM92
Interaction	TMEM255A interactions	NEDD4L NEDD4	3.92e-04	17	35	2	int:TMEM255A
Interaction	MAP3K3 interactions	NEDD4L IP6K3 NEDD4	4.15e-04	84	35	3	int:MAP3K3
Interaction	DUSP3 interactions	GTF2E2 SPANXN4 CASK	4.15e-04	84	35	3	int:DUSP3
Interaction	TMEM174 interactions	NEDD4L NEDD4	4.41e-04	18	35	2	int:TMEM174
Interaction	FAM131C interactions	DNAJA3 SFI1	4.41e-04	18	35	2	int:FAM131C
Interaction	GRIA1 interactions	EPS8 NEDD4L NEDD4	4.45e-04	86	35	3	int:GRIA1
Interaction	SLC9A3 interactions	USP10 NEDD4L	4.92e-04	19	35	2	int:SLC9A3
Interaction	SCN2A interactions	NEDD4L NEDD4	4.92e-04	19	35	2	int:SCN2A
Interaction	TULP4 interactions	CASK NEDD4	4.92e-04	19	35	2	int:TULP4
Interaction	SCN8A interactions	NEDD4L NEDD4	5.46e-04	20	35	2	int:SCN8A
Interaction	STN1 interactions	POLA1 MED13 LRRK2	5.59e-04	93	35	3	int:STN1
Interaction	GRIN2A interactions	EPS8 CASK NEDD4	5.59e-04	93	35	3	int:GRIN2A
Interaction	SCN9A interactions	NEDD4L NEDD4	6.03e-04	21	35	2	int:SCN9A
Interaction	INPP5J interactions	DNAJA3 EPS8	6.03e-04	21	35	2	int:INPP5J
Interaction	KCNQ1 interactions	NEDD4L NEDD4	6.03e-04	21	35	2	int:KCNQ1
Interaction	SLC22A8 interactions	NEDD4L NEDD4	6.62e-04	22	35	2	int:SLC22A8
Interaction	DDIT4 interactions	LRRK2 NEDD4	6.62e-04	22	35	2	int:DDIT4
Interaction	SCNN1G interactions	NEDD4L NEDD4	6.62e-04	22	35	2	int:SCNN1G
Interaction	TMEM51 interactions	EPS8 NEDD4L NEDD4	7.32e-04	102	35	3	int:TMEM51
Interaction	CDK5 interactions	NEDD4L SYNJ1 LRRK2 NEDD4	7.93e-04	242	35	4	int:CDK5
GeneFamily	L ribosomal proteins	RPL22 RPL35	2.07e-03	51	24	2	729
Coexpression	GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_DN	TBX19 SYNJ1 DEPDC1B NLRC4 NEDD4	4.69e-06	192	34	5	M9983
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EPS8 NEDD4L AKAP7 LRRK2	8.56e-06	166	35	4	c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell	AT2_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	EPS8 NEDD4L FGGY LRRK2	1.20e-05	181	35	4	ed0ea67f0607073aedf153f8d1073b35e46127c3
ToppCell	droplet-Spleen-nan-3m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL22L1 RPL35 ELL3	1.37e-05	187	35	4	91c8e93bde0d1d1a4e324b0acf2afda00f4fb3bf
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL22L1 RPL35 ELL3	1.37e-05	187	35	4	382db691eb0b3e089e816bed3d6699cc2d4e1bda
ToppCell	(7)_Epithelial-E_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	EPS8 NEDD4L FGGY LRRK2	1.49e-05	191	35	4	0fc8d109d5c50957ceef5b8b8b818b0c598b1bbe
ToppCell	T/NK_cells-Regulatory_T_cell\|T/NK_cells / Lineage and Cell class	RPL22 USP10 ANKRD12 RPL35	1.58e-05	194	35	4	22843d03366ead435a0cb35092d6f734c225024c
ToppCell	(7)_Epithelial_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	EPS8 NEDD4L FGGY LRRK2	1.58e-05	194	35	4	413e8b9f1e15be363a7f4a8f727af3eeb9e9a928
ToppCell	356C-Epithelial_cells\|356C / Donor, Lineage, Cell class and subclass (all cells)	EPS8 NEDD4L FGGY LRRK2	1.61e-05	195	35	4	d913d0a6c4797d9a873ddea6f340c3f152da1cf3
ToppCell	IIF-Lymphocyte-T_NK-CD4_TCM\|IIF / Disease, Lineage and Cell Type	RPL22 USP10 ANKRD12 RPL35	1.61e-05	195	35	4	8f5d469ef00132637154f6e8847ba4d1e4f008cb
ToppCell	(7)_Epithelial-A_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	EPS8 NEDD4L FGGY LRRK2	1.61e-05	195	35	4	c9a6c65ee18d83bf34a4713d306a6e30db1325c2
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_em-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RPL22 USP10 ANKRD12 RPL35	1.61e-05	195	35	4	48905d57775ec90cc031af0863cc8c3800f2e48e
ToppCell	normal_Lung-Epithelial_cells\|normal_Lung / Location, Cell class and cell subclass	EPS8 NEDD4L FGGY LRRK2	1.61e-05	195	35	4	7c90d887afde5c4d63352b5171be9987e2dfca58
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_em-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	USP10 ANKRD12 RPL35 PSIP1	1.65e-05	196	35	4	ea3caea65e8ddd20a837b4322e7940328c94c15a
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_em\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	USP10 ANKRD12 RPL35 PSIP1	1.65e-05	196	35	4	f7af0af02059aefb968b72a2a27867ad8ff23614
ToppCell	LAM-Epithelial\|LAM / Condition, Lineage and Cell class	EPS8 NEDD4L FGGY LRRK2	1.68e-05	197	35	4	e5cf07061f6d9db7f12ac17209b267373fa2270b
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL22L1 RPL35 NEDD4L	1.68e-05	197	35	4	e5ab45cfe4ebd02ca25029d87bece70dfbb4adc4
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_2-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	EPS8 NEDD4L FGGY LRRK2	1.71e-05	198	35	4	de5748c2b66ecc432974cf095ecd241369579f7c
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_2-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	EPS8 NEDD4L FGGY LRRK2	1.71e-05	198	35	4	19eefd05573fbaed654af52bf0f8a26092b8b229
ToppCell	RSV\|World / Virus stimulation, Condition and Cluster	RPL22 SFI1 RPL22L1 RPL35	1.71e-05	198	35	4	cb2334a37f8c8d0043382dd732ac54d507edc164
ToppCell	AT2_cells\|World / lung cells shred on cell class, cell subclass, sample id	EPS8 NEDD4L FGGY LRRK2	1.71e-05	198	35	4	92c569c3b8a9fca2d4682cbf77ee8149bcc0a80a
ToppCell	CD8+_Memory_T_cell-RSV\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	RPL22 SFI1 RPL22L1 RPL35	1.71e-05	198	35	4	dad352beefbbfa803d1f5e19318f5701694b59d2
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RPL22 RPL22L1 RPL35 PSIP1	1.71e-05	198	35	4	ab17003f5dddc495aa7e1bfb84df66cd2f9113c3
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-B_(AT2)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	RPL22 RPL35 FGGY LRRK2	1.71e-05	198	35	4	391f59e232269f6ae9f8792d21a60ad534e03c4d
ToppCell	distal-1-Epithelial-Alveolar_Epithelial_Type_2\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	EPS8 NEDD4L FGGY LRRK2	1.71e-05	198	35	4	ce9d6b2a93c7b304414ce1b8b1a09562cf581278
ToppCell	Biopsy_Other_PF-Epithelial-AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	EPS8 NEDD4L FGGY LRRK2	1.75e-05	199	35	4	9a65acfe9bf500db72142469cf17bf0973540001
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RPL22 RPL22L1 FGGY LRRK2	1.75e-05	199	35	4	df157604a7e2b6e7fa2d21660ca749a3552b945c
ToppCell	Epithelial_cells\|World / lung cells shred on cell class, cell subclass, sample id	EPS8 NEDD4L FGGY LRRK2	1.75e-05	199	35	4	bbe69e44b7970f57628365ae771790f2b13d0cae
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	EPS8 NEDD4L FGGY LRRK2	1.75e-05	199	35	4	e459d5aa63c83f960562be33cea8182b0556eabf
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RPL22 RPL22L1 FGGY LRRK2	1.75e-05	199	35	4	48626e54ce94b5ea3001fc5d447509a50c073aa4
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_2_alveolar\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	EPS8 NEDD4L FGGY LRRK2	1.75e-05	199	35	4	e28ace2ca680c6154398e17110aa1838dd7a5548
ToppCell	distal-Epithelial\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	EPS8 NEDD4L FGGY LRRK2	1.78e-05	200	35	4	0a97080f694738bb882787cee21b91a4d5757b7a
ToppCell	MS-IIF-Lymphocyte-T/NK-CD4+_Tcm\|IIF / Disease, condition lineage and cell class	RPL22 USP10 ANKRD12 RPL35	1.78e-05	200	35	4	f5c570a03eac54a81921630c79f5bccab05d3452
ToppCell	ASK440-Epithelial\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	EPS8 NEDD4L FGGY LRRK2	1.78e-05	200	35	4	cb617e2a0ca82b470b473b8d5906bc8879c85718
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RPL22 RPL35 PSIP1	2.07e-04	147	35	3	d655e6ede8bca65a62efada2b15c7916e5f19324
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ANKRD12 PSIP1 CASK	2.33e-04	153	35	3	7518187a5fbf6c0881182dc79bd37c2d49f92b2e
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ANKRD12 PSIP1 CASK	2.33e-04	153	35	3	93d36723f01c2df39feebf20f3eba5b4fb4cdf59
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	INTU AK9 CFAP54	2.51e-04	157	35	3	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8 NLRC4 LRRK2	2.61e-04	159	35	3	323cb4a2416d2e6bff0a3f225d2edeae9ab7dc76
ToppCell	COVID-19-kidney-Plasma\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CPNE6 CFAP54 P2RX1	2.66e-04	160	35	3	f8d9e459976e711e9ad39ea2b6173140c0589d6e
ToppCell	-Hematopoietic_Mast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RPL22L1 P2RX1	2.87e-04	32	35	2	ca3d87cac849c1b713acd984626f214f5c8e1433
ToppCell	-Hematopoietic_Mast-Mast_cells-Mast-cells\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RPL22L1 P2RX1	2.87e-04	32	35	2	c6b707107c661f81e5afa945dd62b37a73bfadf9
ToppCell	-Hematopoietic_Mast-Mast_cells\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RPL22L1 P2RX1	2.87e-04	32	35	2	de636b6fbdc9368ef6ce7157acbf84e28330cd94
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RPL22 ANKRD12 CASK	2.91e-04	165	35	3	4edc9714185a7519a7044487a3d6ea845131b851
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-RGCs_early_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	RPL22 RPL35 ELL3	2.91e-04	165	35	3	1917f05a4050e28f669192e45023b0a31c53174b
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RPL22 ANKRD12 CASK	2.91e-04	165	35	3	fd1d38b97564c1f64f5c7246dcec96d60364b7b2
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-STAT1+_Naive_B\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPL35 ELL3 DEPDC1B	3.07e-04	168	35	3	ba127d97697202a8558a0d50bcdafa30b0509de1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 NEDD4L NRDC	3.12e-04	169	35	3	4b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 NEDD4L NRDC	3.12e-04	169	35	3	a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCell	E17.5\|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RPL22 RPL35 NEDD4L	3.12e-04	169	35	3	56aa58636ec624819ca88c8c27a7493c3f8c49fc
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	INTU AK9 CFAP54	3.12e-04	169	35	3	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	COVID-19-kidney-Plasma\|kidney / Disease (COVID-19 only), tissue and cell type	CPNE6 CFAP54 P2RX1	3.23e-04	171	35	3	a59a054b8e119215f24dc5c80ad5a8094b3500f9
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL22 RPL22L1 RPL35	3.28e-04	172	35	3	25bf2551d698237bfd912c2ff067b1600dfb19ca
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Monocytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAF1L NLRC4 LRRK2	3.28e-04	172	35	3	cf46810dd1072b6f2171e5d9530351ddc79a055b
ToppCell	Control-PLT_5\|Control / Disease Group and Platelet Clusters	DNAJA3 EPS8 RPL35	3.28e-04	172	35	3	950d0a5b7908ee6ef8d30f123c9c7f7180dd4c26
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL22 RPL22L1 RPL35	3.34e-04	173	35	3	46dbc51270cc80d6e0b7118c53cec8516b1bb508
ToppCell	droplet\|World / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL22L1 RPL35	3.40e-04	174	35	3	62553b0979e6d8f0b5fb95015f4d7adb116d6269
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL22 RPL22L1 RPL35	3.40e-04	174	35	3	76694cd8a1162047a9ee60521ce84201b4378a47
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL22 RPL22L1 RPL35	3.45e-04	175	35	3	f7547eade69aa1d012db963adf59f36a309beae6
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL22 RPL22L1 RPL35	3.51e-04	176	35	3	3bf8ef0afad8c96f814355ead5b993d58cd1ce35
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL22 RPL22L1 RPL35	3.57e-04	177	35	3	0d6167c6a11c7dec0717ae7c8b4c45341585804f
ToppCell	PND28-Immune\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL22 RPL22L1 RPL35	3.57e-04	177	35	3	087bcda36589e3554e6f2c170542a4be7833cfd2
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	P2RX1 MED13 NLRC4	3.57e-04	177	35	3	68f1139fc378f351e3b9e9f392aacb150025bf03
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL22 RPL22L1 RPL35	3.63e-04	178	35	3	a8d6aae3c35de6e7d1421cc48e58688adbdf16aa
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL22 RPL22L1 RPL35	3.63e-04	178	35	3	61363c3365d3e191c47be1b2a35fa8afbfa64ff2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 NEDD4L NRDC	3.69e-04	179	35	3	e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPS8 NEDD4L LRRK2	3.69e-04	179	35	3	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL22 RPL22L1 RPL35	3.69e-04	179	35	3	1309d41dbf286e9230fde6a7949e60c24d86766a
ToppCell	droplet\|World / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL22L1 RPL35	3.69e-04	179	35	3	1c29ecd294c140d73417bf1c11fe8bd3edd24eb7
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	EPS8 NEDD4L LRRK2	3.75e-04	180	35	3	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL22 RPL22L1 RPL35	3.81e-04	181	35	3	5e1b784c6bd445593855751329ead0eecd5e1736
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	EPS8 NEDD4L LRRK2	3.81e-04	181	35	3	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	facs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL22L1 RPL35	3.87e-04	182	35	3	e7138c8d3821b4141c4b1b23dab6d9b4e99fd4b2
ToppCell	droplet-Pancreas-PANCREAS\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL35 P2RX1	3.87e-04	182	35	3	ecb8c1d0b9e0766fae4dd2568456eb78a3cfce9a
ToppCell	droplet-Pancreas-PANCREAS-30m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL35 P2RX1	3.87e-04	182	35	3	cf1ccfc4709364763fa73e60d5f2c05ce268d5c1
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EPS8 NEDD4L LRRK2	3.94e-04	183	35	3	6847c1252d6bb105524f812658112517fd351eab
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	EPS8 FGGY LRRK2	4.00e-04	184	35	3	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	NEDD4L FGGY LRRK2	4.00e-04	184	35	3	0ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	EPS8 NEDD4L LRRK2	4.00e-04	184	35	3	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	droplet-Spleen-nan-24m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL35 ELL3	4.00e-04	184	35	3	a740ceffa62175578e6cff62da1f8dfaf40098e5
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	GTF2E2 POLA1 ZNF681	4.00e-04	184	35	3	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	NEDD4L FGGY LRRK2	4.00e-04	184	35	3	2a8338e94937686a148b5433515700ca0f674058
ToppCell	droplet-Thymus-nan-24m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL35 ELL3 LRRK2	4.06e-04	185	35	3	a92bd84e44fc992b7eeefaa2ff8091ed09f0df00
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	GTF2E2 POLA1 ZNF681	4.06e-04	185	35	3	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	facs-Thymus-Flowthrough\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL22L1 RPL35	4.06e-04	185	35	3	c0587b32f9925052016a06422ddcdc2ad9b7fc93
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EPS8 NEDD4L LRRK2	4.06e-04	185	35	3	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	droplet\|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL22L1 RPL35	4.06e-04	185	35	3	4c8a25f36cbf43fc78d38dfeb3f1cab160bb029d
ToppCell	droplet-Thymus-nan-24m-Myeloid-professional_antigen_presenting_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL35 ELL3 LRRK2	4.06e-04	185	35	3	877eb127ac797f8a1e1a9e0049fa16cae16cfa35
ToppCell	droplet-Mammary_Gland-nan-3m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL22L1 RPL35	4.06e-04	185	35	3	02a2cbae9238c6c1e80b9a52a575e3b22f0eebb4
ToppCell	droplet-Spleen\|droplet / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL22L1 RPL35	4.06e-04	185	35	3	392c3130c79f7a938b73461c9dded803bb5c5785
ToppCell	droplet-Thymus-nan-24m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL35 ELL3 LRRK2	4.06e-04	185	35	3	d7fed17356f8bf5900fd106f25b4f7501ad7b590
ToppCell	droplet-Spleen-nan-3m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL35 ELL3	4.13e-04	186	35	3	26f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FGGY LRRK2 NEDD4	4.13e-04	186	35	3	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	droplet\|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL22L1 RPL35	4.13e-04	186	35	3	fd69a94144710d63fe047cdc50813f42ac7ab68d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPS8 NEDD4L LRRK2	4.13e-04	186	35	3	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL35 POLA1	4.13e-04	186	35	3	4ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL22 RPL35 POLA1	4.13e-04	186	35	3	15ab6666748a641226e42e6ca6eeaf186a501c95
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	NEDD4L FGGY LRRK2	4.19e-04	187	35	3	11670a85db87cbb3e78022a589632173604b0940
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	NEDD4L FGGY LRRK2	4.19e-04	187	35	3	0277d4e54bd4d48f30241c2951a569209423fee8
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	EPS8 NEDD4L LRRK2	4.19e-04	187	35	3	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEDD4L FGGY LRRK2	4.19e-04	187	35	3	7c44cec1c26ca5907a495f2d7e633410e2e9728f
Disease	Liddle syndrome (implicated_via_orthology)	NEDD4L NEDD4	7.72e-06	4	34	2	DOID:0050477 (implicated_via_orthology)
Disease	PARTINGTON X-LINKED MENTAL RETARDATION SYNDROME	POLA1 CASK	3.59e-05	8	34	2	C0796250
Disease	Parkinsonism, Juvenile	SYNJ1 LRRK2	5.49e-04	30	34	2	C0752105
Disease	Autoinflammatory disorder	POLA1 NLRC4	7.49e-04	35	34	2	C3860213
Disease	unipolar depression, age at onset	INTU NEDD4L	9.78e-04	40	34	2	EFO_0003761, EFO_0004847
Disease	Anorectal Malformations	INTU CASK	1.03e-03	41	34	2	C3495676
Disease	Cleft palate, isolated	NEDD4L CASK	1.08e-03	42	34	2	C1837218
Disease	Parkinson's disease (is_implicated_in)	SYNJ1 LRRK2	3.48e-03	76	34	2	DOID:14330 (is_implicated_in)
Disease	Cleft Palate	NEDD4L CASK	3.94e-03	81	34	2	C0008925

Protein segments in the cluster

Peptide	Gene	Start	Entry
AKQVYYKNKRKDPSK	CFAP54	2566	Q96N23
KIIQEYKKFRKQYPS	ELL3	351	Q9HB65
RKKKRKDYQPNYFLS	AKAP7	76	Q9P0M2
KKKLKQFQKSYPEVY	DEPDC1B	471	Q8WUY9
KQEKAFYPKSFKSKK	ANKRD12	401	Q6UB98
NPKYRDKKKNYKSSG	CPNE6	266	O95741
YYQKDPKNTKFGKSK	ANKRD31	681	Q8N7Z5
FGKKKKQYKDKYLAK	CASK	701	O14936
YKRKYEFFRRKLKKQ	NEDD4	941	P46934
LLCKYTAQRFKPKYK	NLRC4	426	Q9NPP4
VEKFLSKKRKFPKNY	LRRK2	1631	Q5S007
KKYFLCKDKYYGRKL	IP6K3	261	Q96PC2
DTNKYKKGRKKAAYA	POLA1	826	P09884
YKERKKYEPKLKQFT	INTU	101	Q9ULD6
VVFPRLQDKKYYDKK	FGGY	516	Q96C11
KQKERKPKSSAHYYK	KLB	486	Q86Z14
QPKKYAKSKYDFVAR	EPS8	531	Q12929
QKEIKKAYYQLAKKY	DNAJA3	106	Q96EY1
ILPKRHYYKQKKFKY	P2RX1	356	P51575
KYAFKPKYNVRDKKA	GTF2E2	136	P29084
FNPKGSEYTRKKYKK	AK9	1846	Q5TCS8
RYFKDGAVKKPYSAK	SFI1	31	A8K8P3
KENLRKFYKGKKYKP	RPL35	66	P42766
CENFYKYSKPKKIRV	SYNJ1	521	O43426
ATKIKNYYKRKPGKD	TAF1L	716	Q8IZX4
ANIAWKYYKFPKKKD	MED13	611	Q9UHV7
KYYKFPKKKDVEFLP	MED13	616	Q9UHV7
YSENKEKYGKPNKRK	PSIP1	61	O75475
YLKYLTKKYLKKNNL	RPL22L1	76	Q6P5R6
KAKYPTLVFYCRKNK	SPANXN4	46	Q5MJ08
LWYKKDNKFKIPKAY	NRDC	691	O43847
RYLKYLTKKYLKKNN	RPL22	81	P35268
KVRHTRKKPFKYKEF	ZNF681	161	Q96N22
KKKKRPPGYYSYLKD	USP10	151	Q14694
KIKYNPFAKAFLDAK	TBX19	206	O60806
EFKQKYDYFRKKLKK	NEDD4L	596	Q96PU5