Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

RIN1 RASGRF1 RASGRF2 DOCK8 RGL3 DOCK7 DNMBP

1.03e-04231937GO:0005085
GeneOntologyMolecularFunctionneuroligin family protein binding

NRXN3 NRXN2

2.13e-045932GO:0097109
GeneOntologyCellularComponentXY body

RAD18 BRCA1 DAXX

1.37e-0423923GO:0001741
MousePhenoshortened PR interval

TBX3 GPBP1 SCN5A DNAAF1

6.60e-0623764MP:0010511
MousePhenosinus bradycardia

TBX3 SCN5A POPDC2

5.38e-0514763MP:0010637
MousePhenoabnormal tail morphology

PARP4 ZEB1 THRA DMRT2 BRCA1 ROR2 DOCK7 DYNC2I1 HPS5 TBX6

6.20e-054037610MP:0002111
MousePhenodelayed bone ossification

ZEB1 THRA ERF ROR2 CASP3 SUCO

6.49e-05127766MP:0000060
MousePhenoenlarged tail bud

BRCA1 TBX6

8.72e-053762MP:0003401
MousePhenoabnormal fibrous joint morphology

ZEB1 THRA ROR2 CASP3 SUCO TBX6

9.12e-05135766MP:0030878
DomainRas_G-nucl-exch_fac_CS

RASGRF1 RASGRF2 RGL3

4.18e-0514933IPR019804
DomainMAP1

MAP1A MAP1B

7.33e-053932IPR026074
DomainRasGEFN

RASGRF1 RASGRF2 RGL3

1.28e-0420933SM00229
DomainRasGEF_N

RASGRF1 RASGRF2 RGL3

1.49e-0421933PF00618
DomainRas-like_Gua-exchang_fac_N

RASGRF1 RASGRF2 RGL3

1.72e-0422933IPR000651
DomainRASGEF_NTER

RASGRF1 RASGRF2 RGL3

1.72e-0422933PS50212
DomainRASGEF

RASGRF1 RASGRF2 RGL3

2.86e-0426933PS00720
DomainDUF3398

DOCK8 DOCK7

3.63e-046932PF11878
DomainDOCK_C/D_N

DOCK8 DOCK7

3.63e-046932IPR021816
DomainRASGEF_CAT

RASGRF1 RASGRF2 RGL3

3.98e-0429933PS50009
DomainRasGEF

RASGRF1 RASGRF2 RGL3

4.40e-0430933PF00617
Domain-

RASGRF1 RASGRF2 RGL3

4.40e-04309331.10.840.10
DomainRas_GEF_dom

RASGRF1 RASGRF2 RGL3

4.40e-0430933IPR023578
DomainRASGEF_cat_dom

RASGRF1 RASGRF2 RGL3

4.40e-0430933IPR001895
DomainRasGEF

RASGRF1 RASGRF2 RGL3

4.40e-0430933SM00147
DomainSyndecan

NRXN3 NRXN2

5.07e-047932PF01034
DomainSyndecan/Neurexin_dom

NRXN3 NRXN2

5.07e-047932IPR027789
DomainDOCK_C

DOCK8 DOCK7

1.31e-0311932IPR010703
DomainDHR-1_domain

DOCK8 DOCK7

1.31e-0311932IPR027007
DomainDHR_2

DOCK8 DOCK7

1.31e-0311932PS51651
DomainDHR_1

DOCK8 DOCK7

1.31e-0311932PS51650
DomainDOCK-C2

DOCK8 DOCK7

1.31e-0311932PF14429
DomainDHR-2

DOCK8 DOCK7

1.31e-0311932IPR027357
DomainDHR-2

DOCK8 DOCK7

1.31e-0311932PF06920
DomainDOCK

DOCK8 DOCK7

1.31e-0311932IPR026791
DomainLamG

NRXN3 COL15A1 NRXN2

1.37e-0344933SM00282
DomainNeurexin-like

NRXN3 NRXN2

2.15e-0314932IPR003585
Domain4.1m

NRXN3 NRXN2

2.15e-0314932SM00294
DomainARM-like

KPNA4 COPG1 DOCK8 DAXX CUL7 HEATR5B

2.30e-03270936IPR011989
DomainPH

IRS4 RASGRF1 RASGRF2 OSBPL5 SH2B2 TECPR1

2.66e-03278936SM00233
DomainPH_DOMAIN

IRS4 RASGRF1 RASGRF2 OSBPL5 SH2B2 TECPR1

2.71e-03279936PS50003
DomainPH_domain

IRS4 RASGRF1 RASGRF2 OSBPL5 SH2B2 TECPR1

2.76e-03280936IPR001849
DomainLaminin_G

NRXN3 COL15A1 NRXN2

3.03e-0358933IPR001791
DomainTF_T-box

TBX3 TBX6

3.18e-0317932IPR001699
DomainTBOX

TBX3 TBX6

3.18e-0317932SM00425
DomainTF_T-box_CS

TBX3 TBX6

3.18e-0317932IPR018186
Domain-

TBX3 TBX6

3.18e-03179322.60.40.820
DomainTBOX_3

TBX3 TBX6

3.18e-0317932PS50252
DomainT-box

TBX3 TBX6

3.18e-0317932PF00907
DomainTBOX_1

TBX3 TBX6

3.18e-0317932PS01283
DomainTBOX_2

TBX3 TBX6

3.18e-0317932PS01264
DomainDH_1

RASGRF1 RASGRF2 DNMBP

3.82e-0363933PS00741
DomainBRCT

PARP4 BRCA1

3.97e-0319932PF00533
Domain-

MAP1A MAP1B

4.40e-03209323.60.15.10
DomainMetallo-B-lactamas

MAP1A MAP1B

4.40e-0320932IPR001279
DomainRhoGEF

RASGRF1 RASGRF2 DNMBP

4.74e-0368933SM00325
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TBX3 RAD18 THRA ERF BRCA1 MAP1A CFAP36 CHAF1A BACH2 SCN5A CUL7 PIP4K2C CLSPN SRCAP MAST2 WDR37 PCM1

8.74e-091116951731753913
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NCOR1 IRS4 KMT2B MAP1B PHACTR4 DOCK7 GIGYF2 EDC4 PATJ SRCAP PCM1 WDR44

3.54e-08549951238280479
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

NCOR1 RAD18 MAP1A BACH2 DAXX CUL7 PIP4K2C CLSPN PATJ SRCAP DNMBP PCM1

7.45e-08588951238580884
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

IRS4 GPBP1 MAP1B EXPH5 SRGAP1 ROR2 PHACTR4 DOCK7 GIGYF2 EDC4 PATJ MAST2 DNMBP PCM1

9.35e-08861951436931259
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

NCOR1 RGL3 PHACTR4 PDE4DIP OSBPL5 DNAJB2 TSGA10IP TECPR1

2.65e-0723395837704626
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NCOR1 RAD18 ZEB1 KMT2B CHAF1A PHACTR4 RRP15 GIGYF2 DAXX DNMBP PCM1 WDR44

1.37e-06774951215302935
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

MAP1B DOCK8 DOCK7 CASP3 WDR37 CAPRIN1

1.76e-0613295616944949
Pubmed

A conserved acetylation switch enables pharmacological control of tubby-like protein stability.

RAD18 BACH2 FLAD1 PDE4DIP CUL7 PIP4K2C DNMBP

2.78e-0622395733187986
Pubmed

Control of p21Cip by BRCA1-associated protein is critical for cardiomyocyte cell cycle progression and survival.

CASP3 CCND1 PCM1

3.21e-061195331286143
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NCOR1 AREL1 KMT2B MAST2 TECPR1

4.23e-068795512465718
Pubmed

Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation.

CHAF1A DAXX DEK CAPRIN1

4.43e-064095428805822
Pubmed

RASGRF2 controls nuclear migration in postnatal retinal cone photoreceptors.

RASGRF1 RASGRF2

7.38e-06295226743081
Pubmed

Caspase-3 mediated cleavage of BRCA1 during UV-induced apoptosis.

BRCA1 CASP3

7.38e-06295212149654
Pubmed

Regulation of microtubule-associated protein 1B (MAP1B) subunit composition.

MAP1A MAP1B

7.38e-06295211002287
Pubmed

Aberrant dynamics of histone deacetylation at the thyrotropin-releasing hormone gene in resistance to thyroid hormone.

NCOR1 THRA

7.38e-06295215131262
Pubmed

Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression.

RASGRF1 RASGRF2

7.38e-06295216467520
Pubmed

NCOR1 modulates erythroid disorders caused by mutations of thyroid hormone receptor α1.

NCOR1 THRA

7.38e-06295229273766
Pubmed

Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1.

BRCA1 EDC4

7.38e-06295229511213
Pubmed

Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation.

BRCA1 CLSPN

7.38e-06295215096610
Pubmed

The environment versus genetics in controlling the contribution of MAP kinases to synaptic plasticity.

RASGRF1 RASGRF2

7.38e-06295217141611
Pubmed

DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice.

ZBTB20 BRCA1

7.38e-06295226615780
Pubmed

Multiple mechanisms regulate H3 acetylation of enhancers in response to thyroid hormone.

NCOR1 THRA

7.38e-06295232453730
Pubmed

Heterotypic complex formation between subunits of microtubule-associated proteins 1A and 1B is due to interaction of conserved domains.

MAP1A MAP1B

7.38e-06295216996626
Pubmed

Transgenerational rescue of a genetic defect in long-term potentiation and memory formation by juvenile enrichment.

RASGRF1 RASGRF2

7.38e-06295219193896
Pubmed

Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors.

RASGRF1 RASGRF2

7.38e-06295214749369
Pubmed

The mouse and rat MAP1B genes: genomic organization and alternative transcription.

MAP1A MAP1B

7.38e-0629529615228
Pubmed

Daxx contains two nuclear localization signals and interacts with importin alpha3.

KPNA4 DAXX

7.38e-06295217661348
Pubmed

A murine CDC25/ras-GRF-related protein implicated in Ras regulation.

RASGRF1 RASGRF2

7.38e-0629528293576
Pubmed

Delayed development of nervous system in mice homozygous for disrupted microtubule-associated protein 1B (MAP1B) gene.

MAP1A MAP1B

7.38e-0629529199175
Pubmed

Cloning of human microtubule-associated protein 1B and the identification of a related gene on chromosome 15.

MAP1A MAP1B

7.38e-0629527806212
Pubmed

Nuclear receptor corepressor (NCOR1) regulates in vivo actions of a mutated thyroid hormone receptor α.

NCOR1 THRA

7.38e-06295223610395
Pubmed

Ras-GRF2 regulates nestin-positive stem cell density and onset of differentiation during adult neurogenesis in the mouse dentate gyrus.

RASGRF1 RASGRF2

7.38e-06295228966131
Pubmed

BRCA1 mRNA expression modifies the effect of T cell activation score on patient survival in breast cancer.

BRCA1 CCND1

7.38e-06295231023256
Pubmed

A histone deacetylase inhibitor improves hypothyroidism caused by a TRα1 mutant.

NCOR1 THRA

7.38e-06295224381310
Pubmed

The Inhibition of RasGRF2, But Not RasGRF1, Alters Cocaine Reward in Mice.

RASGRF1 RASGRF2

7.38e-06295231182637
Pubmed

Neuronal abnormalities in microtubule-associated protein 1B mutant mice.

MAP1A MAP1B

7.38e-0629528577753
Pubmed

Molecular cloning of microtubule-associated protein 1 (MAP1A) and microtubule-associated protein 5 (MAP1B): identification of distinct genes and their differential expression in developing brain.

MAP1A MAP1B

7.38e-0629522355215
Pubmed

Human transcription factor protein interaction networks.

NCOR1 ASXL1 RAD18 IRS4 ZEB1 ERF KMT2B BRCA1 RRP15 GIGYF2 CUL7 EDC4 SRCAP CAPRIN1 PCM1

7.50e-061429951535140242
Pubmed

A human MAP kinase interactome.

KPNA4 TBX3 MAP1A EXPH5 CFAP36 CHAF1A GIGYF2 DAXX WDR44

7.66e-0648695920936779
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ASXL1 NRXN2 HPS5 WDR37 DNMBP

9.24e-0610295510231032
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

TBX3 PARP4 ERF MAP1B DOCK7 GIGYF2 CLSPN PATJ HPS5 MAST2

1.18e-05650951038777146
Pubmed

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.

NCOR1 ZEB1 ZBTB20 DOCK7

1.38e-055395421532573
Pubmed

Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling.

KMT2B GIGYF2 PCM1

1.56e-051895319640993
Pubmed

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3.

KPNA4 CHAF1A DAXX

1.85e-051995320504901
Pubmed

Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis.

CASP3 CCND1 PATJ

1.85e-051995322398208
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PIK3AP1 NCOR1 GPBP1 BACH2 PHACTR4 DYNC2I1 GIGYF2 MAST2 DNMBP LRP1B PCM1

2.17e-05853951128718761
Pubmed

Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.

NRXN3 NRXN2

2.21e-05395238891114
Pubmed

RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation.

RASGRF1 RASGRF2

2.21e-05395221685891
Pubmed

alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.

NRXN3 NRXN2

2.21e-05395216406382
Pubmed

Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development.

RASGRF1 RASGRF2

2.21e-05395211909944
Pubmed

Interaction of tubby-like protein-1 (Tulp1) and microtubule-associated protein (MAP) 1A and MAP1B in the mouse retina.

MAP1A MAP1B

2.21e-05395224664738
Pubmed

Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses.

NRXN3 NRXN2

2.21e-05395231005376
Pubmed

Interaction of PDZRhoGEF with microtubule-associated protein 1 light chains: link between microtubules, actin cytoskeleton, and neuronal polarity.

MAP1A MAP1B

2.21e-05395216478718
Pubmed

Cyclin D1 antagonizes BRCA1 repression of estrogen receptor alpha activity.

BRCA1 CCND1

2.21e-05395216061635
Pubmed

Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals.

NRXN3 NRXN2

2.21e-05395226446217
Pubmed

Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.

NRXN3 NRXN2

2.21e-05395211944992
Pubmed

Alternative splicing of neurexins 1-3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis.

NRXN3 NRXN2

2.21e-05395233058888
Pubmed

Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.

NRXN3 NRXN2

2.21e-05395217035546
Pubmed

Neurexins: three genes and 1001 products.

NRXN3 NRXN2

2.21e-0539529448462
Pubmed

Deletion of α-neurexin II results in autism-related behaviors in mice.

NRXN3 NRXN2

2.21e-05395225423136
Pubmed

Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB.

RASGRF1 RASGRF2

2.21e-05395215029245
Pubmed

Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.

NRXN3 NRXN2

2.21e-05395234133920
Pubmed

The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice.

NRXN3 NRXN2

2.21e-05395230858964
Pubmed

In vivo repression of an erythroid-specific gene by distinct corepressor complexes.

NCOR1 THRA

2.21e-05395211889044
Pubmed

Thyroid Hormone Receptors Predict Prognosis in BRCA1 Associated Breast Cancer in Opposing Ways.

THRA BRCA1

2.21e-05395226029931
Pubmed

MAP 1A and MAP 1B are structurally related microtubule associated proteins with distinct developmental patterns in the CNS.

MAP1A MAP1B

2.21e-0539522470876
Pubmed

Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.

NRXN3 NRXN2

2.21e-05395228013231
Pubmed

Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion.

NRXN3 NRXN2

2.21e-05395231812984
Pubmed

Microtubule-associated proteins, MAP 1A and MAP 1B, interact with F-actin in vitro.

MAP1A MAP1B

2.21e-0539527908020
Pubmed

Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing.

NRXN3 NRXN2

2.21e-05395212036300
Pubmed

β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling.

NRXN3 NRXN2

2.21e-05395226213384
Pubmed

Neurexin gene family variants as risk factors for autism spectrum disorder.

NRXN3 NRXN2

2.21e-05395229045040
Pubmed

Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.

NRXN3 NRXN2

2.21e-05395238571813
Pubmed

Deletion of β-Neurexins in Mice Alters the Distribution of Dense-Core Vesicles in Presynapses of Hippocampal and Cerebellar Neurons.

NRXN3 NRXN2

2.21e-05395235173587
Pubmed

BRCA1-IRIS activates cyclin D1 expression in breast cancer cells by downregulating the JNK phosphatase DUSP3/VHR.

BRCA1 CCND1

2.21e-05395217278098
Pubmed

Defective release of corepressor by hinge mutants of the thyroid hormone receptor found in patients with resistance to thyroid hormone.

NCOR1 THRA

2.21e-0539529804773
Pubmed

Neurexins are differentially expressed in the embryonic nervous system of mice.

NRXN3 NRXN2

2.21e-0539527722633
Pubmed

The functional relationship between co-repressor N-CoR and SMRT in mediating transcriptional repression by thyroid hormone receptor alpha.

NCOR1 THRA

2.21e-05395218052923
Pubmed

The light chains of microtubule-associated proteins MAP1A and MAP1B interact with α1-syntrophin in the central and peripheral nervous system.

MAP1A MAP1B

2.21e-05395223152929
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

IRS4 MAP1B PDE4DIP CCND1 CUL7 PIP4K2C PATJ DEK

2.51e-0543295823455922
Pubmed

The LIFEdb database in 2006.

PIK3AP1 ZBTB20 TXLNB GPBP1 CNST OSBPL5 CCND1 WDR37 HORMAD1 WDR44

2.82e-05720951016381901
Pubmed

From ORFeome to biology: a functional genomics pipeline.

PIK3AP1 ZBTB20 TXLNB GPBP1 CNST OSBPL5 CCND1 WDR37 HORMAD1 WDR44

2.89e-05722951015489336
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

PARP4 BRCA1 MAP1A MAP1B COPG1 DOCK7 GIGYF2 DAXX DNMBP CAPRIN1

2.96e-05724951036232890
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

IRS4 DOCK8 DOCK7 GIGYF2 CUL7 PATJ MAST2 PCM1

3.15e-0544695824255178
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

RIN1 MAP1A MAP1B NRXN2 DOCK8 CRACDL PDE4DIP DOCK7 EDC4 PIP4K2C WDR37 CAPRIN1 JMY PCM1

3.39e-051431951437142655
Pubmed

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.

IRS4 MAP1B DOCK7 RRP15 PATJ DEK CAPRIN1

3.79e-0533495730425250
Pubmed

Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism.

MAP1A MAP1B CASP3

3.83e-052495325505152
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PIK3AP1 ZBTB20 TXLNB GPBP1 CNST OSBPL5 CD320 WDR37 HORMAD1 WDR44

3.98e-05750951011230166
Pubmed

Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription.

KMT2B CASP3 CCND1

4.35e-052595325664857
Pubmed

Pathway analysis of single-nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forests.

BRCA1 CHAF1A

4.41e-05495218559551
Pubmed

An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis.

THRA CCND1

4.41e-05495215601836
Pubmed

A DNA-damage selective role for BRCA1 E3 ligase in claspin ubiquitylation, CHK1 activation, and DNA repair.

BRCA1 CLSPN

4.41e-05495222863316
Pubmed

Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism.

NRXN3 NRXN2

4.41e-05495232706374
Pubmed

Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression.

DOCK7 CCND1

4.41e-05495224870244
Pubmed

Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factors.

RASGRF1 RASGRF2

4.41e-05495219692568
Pubmed

Functional consequences of cyclin D1/BRCA1 interaction in breast cancer cells.

BRCA1 CCND1

4.41e-05495217334399
Pubmed

A novel natural mutation in the thyroid hormone receptor defines a dual functional domain that exchanges nuclear receptor corepressors and coactivators.

NCOR1 THRA

4.41e-0549529849963
Pubmed

CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins.

NRXN3 NRXN2

4.41e-0549528786425
Pubmed

Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation.

NRXN3 NRXN2

4.41e-05495217347997
Pubmed

RasGRF Couples Nox4-Dependent Endoplasmic Reticulum Signaling to Ras.

RASGRF1 RASGRF2

4.41e-05495227856453
InteractionYWHAZ interactions

RIN1 NCOR1 ASXL1 ADRA2B IRS4 BRCA1 GPBP1 RASGRF1 RASGRF2 EXPH5 SRGAP1 CHAF1A ROR2 PHACTR4 DOCK7 GIGYF2 CUL7 MAST2 WDR37 DNMBP SUCO DEK ZRANB1 PCM1

6.72e-0913199524int:YWHAZ
InteractionYWHAE interactions

RIN1 RAD18 IRS4 BRCA1 GPBP1 MAP1B RASGRF1 DOCK8 EXPH5 SRGAP1 CHAF1A PHACTR4 DOCK7 CASP3 GIGYF2 CUL7 MAST2 WDR37 DNMBP ZRANB1 CAPRIN1 PCM1

6.46e-0812569522int:YWHAE
InteractionYWHAH interactions

RIN1 IRS4 THRA GPBP1 EXPH5 SRGAP1 ROR2 PHACTR4 OSBPL5 DOCK7 GIGYF2 EDC4 PATJ MAST2 WDR37 DNMBP SUCO ZRANB1 PCM1

7.66e-0711029519int:YWHAH
InteractionYWHAB interactions

RIN1 IRS4 RASGRF1 EXPH5 SRGAP1 CHAF1A ROR2 PHACTR4 DOCK7 GIGYF2 CUL7 PIP4K2C MAST2 WDR37 DNMBP SUCO ZRANB1 PCM1

1.04e-0610149518int:YWHAB
InteractionYWHAG interactions

RIN1 IRS4 GPBP1 EXPH5 SRGAP1 CHAF1A ROR2 PHACTR4 DOCK7 CASP3 GIGYF2 CUL7 EDC4 PATJ MAST2 WDR37 DNMBP SUCO ZRANB1 PCM1

1.17e-0612489520int:YWHAG
InteractionMCRS1 interactions

ERF KMT2B BRCA1 GPBP1 BACH2 DAXX SH2B2 ZRANB1 PCM1

1.68e-06235959int:MCRS1
InteractionCSNK2A1 interactions

KPNA4 NCOR1 ASXL1 RAD18 IRS4 ZEB1 KMT2B BRCA1 CCDC82 RRP15 DAXX CUL7 PIP4K2C DNAJB2 DEK ZRANB1 WDR44

2.11e-069569517int:CSNK2A1
InteractionTK1 interactions

KMT2B FLAD1 PDE4DIP DOCK7 DYNC2I1 CCND1 CUL7 MAST2 ZRANB1

2.22e-06243959int:TK1
InteractionCAD interactions

ASXL1 NRBP2 ZEB1 BRCA1 MAP1B CHAF1A CASP3 GIGYF2 CCND1 CUL7 ZRANB1

4.39e-064189511int:CAD
InteractionWWTR1 interactions

NCOR1 IRS4 ZEB1 MAP1B PHACTR4 DOCK7 EDC4 PATJ SRCAP PCM1 WDR44

4.80e-064229511int:WWTR1
InteractionBAG2 interactions

NCOR1 ASXL1 RAD18 MAP1B EXPH5 PHACTR4 DOCK7 CCND1 CUL7 EDC4 HPS5 DNAJB2 ZRANB1

6.97e-066229513int:BAG2
InteractionFAM161A interactions

TXLNB BRCA1 GPBP1 DOCK8 BACH2 PDE4DIP ZRANB1

9.09e-06156957int:FAM161A
InteractionRBBP4 interactions

KPNA4 NCOR1 ASXL1 RAD18 ZEB1 ZBTB20 BRCA1 CHAF1A CCND1 CUL7 ZRANB1 CAPRIN1

1.59e-055739512int:RBBP4
InteractionYWHAQ interactions

IRS4 THRA BRCA1 GPBP1 EXPH5 SRGAP1 CHAF1A ROR2 PHACTR4 DOCK7 CUL7 MAST2 WDR37 DNMBP SUCO ZRANB1 PCM1

1.67e-0511189517int:YWHAQ
InteractionPPARD interactions

RIN1 NCOR1 ERF RGL3 CUL7 DNMBP

1.92e-05117956int:PPARD
InteractionDBF4 interactions

RAD18 BRCA1 CHAF1A DAXX

1.93e-0534954int:DBF4
InteractionTUBB6 interactions

FOCAD IRS4 BRCA1 ROR2 CCND1 CUL7 DNAJB2 ZRANB1

1.96e-05243958int:TUBB6
InteractionGRB7 interactions

RIN1 KMT2B FLAD1 DOCK7 GIGYF2 ZRANB1 CAPRIN1

2.14e-05178957int:GRB7
InteractionUBXN6 interactions

RIN1 IRS4 ERF RGL3 DOCK7 CCND1 CUL7 HPS5 DNMBP

2.30e-05325959int:UBXN6
InteractionAFDN interactions

RIN1 NRXN3 NRXN2 ROR2 PHACTR4 CUL7 PATJ DNMBP ZRANB1

2.78e-05333959int:AFDN
InteractionPRKCSH interactions

BRCA1 MAP1B COPG1 DOCK8 DOCK7 CUL7 ZRANB1 CAPRIN1

2.93e-05257958int:PRKCSH
InteractionTBL1XR1 interactions

NCOR1 IRS4 THRA ERF BRCA1 CCND1 ZRANB1

3.48e-05192957int:TBL1XR1
InteractionCSNK2B interactions

ERICH1 RAD18 KMT2B BRCA1 CCDC82 RRP15 DAXX CUL7 PIP4K2C CLSPN DEK ZRANB1

3.72e-056259512int:CSNK2B
InteractionMORC3 interactions

KPNA4 BRCA1 DOCK8 DAXX ZRANB1

3.81e-0580955int:MORC3
InteractionGCN1 interactions

ASXL1 RAD18 NRBP2 BRCA1 COPG1 CCND1 CUL7 MAST2 ZRANB1

4.01e-05349959int:GCN1
InteractionBPTF interactions

NCOR1 RAD18 BRCA1 CHAF1A CUL7 DEK ZRANB1

4.10e-05197957int:BPTF
InteractionARL16 interactions

ERICH1 NCOR1 BRCA1 CLSPN PCM1

4.55e-0583955int:ARL16
InteractionCBX3 interactions

ERICH1 NCOR1 RAD18 ZEB1 KMT2B BRCA1 CHAF1A DAXX CUL7 CLSPN DEK ZRANB1

5.12e-056469512int:CBX3
InteractionMKI67 interactions

KPNA4 BRCA1 MAP1B OSBPL5 DOCK7 RRP15 DAXX CCND1 CUL7 DNMBP ZRANB1 CAPRIN1

5.27e-056489512int:MKI67
InteractionTERF2IP interactions

KPNA4 ERICH1 NCOR1 RAD18 ZEB1 KMT2B BRCA1 CHAF1A CLSPN SRCAP ZRANB1

5.76e-055529511int:TERF2IP
InteractionCDKN1A interactions

NCOR1 IRS4 KMT2B FLAD1 PDE4DIP DOCK7 CASP3 GIGYF2 CCND1

6.98e-05375959int:CDKN1A
InteractionMAGED1 interactions

IRS4 DMRT2 COPG1 ROR2 TSGA10IP ZRANB1 PCM1 TBX6

7.74e-05295958int:MAGED1
InteractionEMD interactions

NCOR1 ASXL1 TBX3 IRS4 ZEB1 THRA DNAJC14 COPG1 ROR2 GIGYF2 CUL7 SUCO ZRANB1

8.29e-057899513int:EMD
InteractionSMARCC1 interactions

KPNA4 NCOR1 RAD18 BRCA1 CHAF1A SRCAP DEK ZRANB1 CAPRIN1

8.37e-05384959int:SMARCC1
InteractionCDK8 interactions

TBX3 RAD18 THRA BRCA1 SRGAP1 CCND1 DEK

8.70e-05222957int:CDK8
InteractionSFN interactions

IRS4 GPBP1 MAP1A MAP1B EXPH5 ROR2 DOCK7 EDC4 MAST2 DNMBP DEK ZRANB1

9.85e-056929512int:SFN
InteractionTNPO1 interactions

KPNA4 ASXL1 BRCA1 MAP1B DAXX CUL7 SUCO ZRANB1

9.98e-05306958int:TNPO1
InteractionPRKDC interactions

NCOR1 ASXL1 RAD18 NRBP2 ZEB1 THRA BRCA1 MAP1B CHAF1A CASP3 CUL7 ZRANB1

1.03e-046959512int:PRKDC
InteractionCREBBP interactions

NCOR1 ZEB1 THRA BRCA1 GPBP1 MAP1B CHAF1A DAXX CCND1 SRCAP DEK

1.19e-045999511int:CREBBP
InteractionRAC1 interactions

KPNA4 USP6 IRS4 RASGRF1 RASGRF2 DOCK8 CFAP36 SRGAP1 ROR2 PHACTR4 DOCK7 CASP3 CD320 DNMBP ZRANB1

1.29e-0410639515int:RAC1
InteractionNOLC1 interactions

KPNA4 RAD18 BRCA1 COPG1 DAXX CUL7 PIP4K2C ZRANB1

1.51e-04325958int:NOLC1
InteractionNRIP1 interactions

KPNA4 NCOR1 THRA BRCA1 DYNC2I1 ZRANB1

1.54e-04170956int:NRIP1
InteractionHSPB8 interactions

RIN1 ZBTB20 ERF MAP1B EXPH5 RGL3

1.64e-04172956int:HSPB8
InteractionAFP interactions

ASXL1 CASP3 ZRANB1

1.68e-0423953int:AFP
InteractionDHX16 interactions

TXLNB CUL7 DEK ZRANB1 CAPRIN1 WDR44

1.70e-04173956int:DHX16
InteractionSULT1C4 interactions

ERF RGL3 DOCK7 GIGYF2 DNMBP

1.73e-04110955int:SULT1C4
InteractionRFC2 interactions

RAD18 BRCA1 CHAF1A DAXX CCND1 ZRANB1

1.75e-04174956int:RFC2
InteractionASF1A interactions

NCOR1 KMT2B BRCA1 CHAF1A CLSPN SRCAP ZRANB1

1.77e-04249957int:ASF1A
InteractionPPP1CC interactions

KPNA4 NCOR1 RAD18 BRCA1 CNST RNF19B PHACTR4 RRP15 CCND1 CUL7 WDR37 ZRANB1

1.80e-047389512int:PPP1CC
InteractionMLF1 interactions

MAP1B EXPH5 PDE4DIP HEATR5B DNAJB2

1.97e-04113955int:MLF1
InteractionCREB1 interactions

NCOR1 THRA TXLNB BRCA1 DAXX CCND1 ZRANB1

2.00e-04254957int:CREB1
InteractionHDAC1 interactions

KPNA4 NCOR1 TBX3 IRS4 ZEB1 KMT2B BRCA1 CHAF1A DOCK7 GIGYF2 DAXX CCND1 ZRANB1 CAPRIN1 PCM1

2.03e-0411089515int:HDAC1
InteractionH3-3A interactions

KPNA4 ERICH1 RAD18 KMT2B BRCA1 CHAF1A OSBPL5 DYNC2I1 RRP15 DAXX SRCAP DEK

2.06e-047499512int:H3-3A
InteractionHDAC2 interactions

KPNA4 NCOR1 TBX3 ZEB1 THRA BRCA1 CHAF1A DAXX CCND1 CUL7 DEK ZRANB1 CAPRIN1

2.06e-048659513int:HDAC2
InteractionLPXN interactions

CEP68 TXLNB SRGAP1 DNMBP PCM1

2.13e-04115955int:LPXN
InteractionSOHLH1 interactions

RIN1 EXPH5 DOCK7 CASP3 CUL7

2.13e-04115955int:SOHLH1
InteractionCETN1 interactions

FOCAD BRCA1 CUL7 PCM1

2.23e-0463954int:CETN1
InteractionTULP3 interactions

NCOR1 RAD18 BACH2 FLAD1 PDE4DIP CUL7 PIP4K2C DNMBP

2.31e-04346958int:TULP3
InteractionAVEN interactions

FOCAD BRCA1 ZRANB1

2.44e-0426953int:AVEN
InteractionB4GALT2 interactions

RIN1 NCOR1 ERF RGL3 DNMBP

2.50e-04119955int:B4GALT2
InteractionMIF interactions

NCOR1 ASXL1 DOCK7 GIGYF2 CUL7 CLSPN ZRANB1

2.53e-04264957int:MIF
InteractionHSPH1 interactions

ZEB1 BRCA1 MAP1B CHAF1A ROR2 CCND1 PIP4K2C ZRANB1 WDR44

2.65e-04448959int:HSPH1
InteractionAPEX1 interactions

USP6 RAD18 ZEB1 KMT2B BRCA1 CHAF1A FLAD1 R3HCC1 RRP15 GIGYF2 DAXX SRCAP SUCO DEK ZRANB1 PCM1

2.78e-0412719516int:APEX1
InteractionSP110 interactions

RAD18 BACH2 CUL7 CLSPN PCM1

2.81e-04122955int:SP110
InteractionDMAP1 interactions

TXLNB CHAF1A DAXX SRCAP TSGA10IP ZRANB1

2.89e-04191956int:DMAP1
InteractionMSH6 interactions

BRCA1 CHAF1A CCND1 CUL7 CLSPN ZRANB1 CAPRIN1

2.97e-04271957int:MSH6
InteractionHSPA4 interactions

FOCAD NCOR1 IRS4 ZEB1 THRA BRCA1 MAP1B EXPH5 DNMBP DNAJB2 ZRANB1

3.01e-046679511int:HSPA4
InteractionPARG interactions

BRCA1 CASP3 ZRANB1

3.05e-0428953int:PARG
InteractionEWSR1 interactions

ERICH1 NCOR1 TBX3 ZEB1 BRCA1 CNST CHAF1A RRP15 CUL7 WDR37 LRP1B ZRANB1 PCM1

3.23e-049069513int:EWSR1
InteractionSAFB2 interactions

NCOR1 RAD18 MAP1B CUL7 SRCAP ZRANB1

3.23e-04195956int:SAFB2
InteractionSMARCB1 interactions

KPNA4 NCOR1 KMT2B BRCA1 CHAF1A SRCAP DEK ZRANB1

3.25e-04364958int:SMARCB1
InteractionEEF1AKMT3 interactions

RIN1 ERF RGL3 DOCK7 CUL7 PATJ HPS5 DNMBP

3.25e-04364958int:EEF1AKMT3
InteractionSRGAP2 interactions

SRGAP1 ROR2 GIGYF2 DNMBP ZRANB1 PCM1

3.41e-04197956int:SRGAP2
InteractionCCT6A interactions

KPNA4 ASXL1 PARP4 RAD18 BRCA1 MAP1B CCND1 CUL7 WDR37 ZRANB1

3.54e-045709510int:CCT6A
InteractionADNP interactions

KPNA4 MAP1B COPG1 CHAF1A DAXX ZRANB1

3.60e-04199956int:ADNP
InteractionJUN interactions

CEP68 USP6 NCOR1 BRCA1 BACH2 RRP15 DAXX CCND1 EDC4

3.77e-04470959int:JUN
InteractionTNRC6B interactions

BRCA1 GPBP1 FLAD1 GIGYF2 DNMBP ZRANB1 CAPRIN1

3.77e-04282957int:TNRC6B
InteractionRCC1 interactions

KPNA4 KMT2B FLAD1 CUL7 DNAJB2 ZRANB1

3.80e-04201956int:RCC1
InteractionDPY30 interactions

KMT2B BRCA1 DAXX CCND1 PIP4K2C ZRANB1

4.11e-04204956int:DPY30
InteractionFAM133B interactions

RAD18 RRP15 ZRANB1

4.14e-0431953int:FAM133B
InteractionCAPN10 interactions

MAP1A MAP1B DOCK7

4.56e-0432953int:CAPN10
InteractionTRIM28 interactions

KPNA4 NCOR1 ASXL1 RAD18 IRS4 BRCA1 MAP1A MAP1B COPG1 CHAF1A CASP3 DAXX CCND1 CUL7 EDC4 SRCAP ZRANB1

4.86e-0414749517int:TRIM28
InteractionLCMT1 interactions

BRCA1 CASP3 ZRANB1

5.00e-0433953int:LCMT1
InteractionZZZ3 interactions

KMT2B BRCA1 EDC4 WDR37 ZRANB1

5.12e-04139955int:ZZZ3
InteractionPARD3 interactions

KPNA4 IRS4 ROR2 PHACTR4 PATJ DNMBP ZRANB1

5.24e-04298957int:PARD3
InteractionHMGA2 interactions

KPNA4 ASXL1 CHAF1A ROR2 ZRANB1

5.29e-04140955int:HMGA2
InteractionSMN1 interactions

KMT2B FLAD1 PDE4DIP DOCK7 GIGYF2 MAST2 ZRANB1

5.35e-04299957int:SMN1
InteractionUSO1 interactions

CEP68 BRCA1 CHAF1A PDE4DIP CASP3 ZRANB1

5.43e-04215956int:USO1
InteractionTADA3 interactions

TXLNB KMT2B EDC4 WDR37 ZRANB1

5.46e-04141955int:TADA3
InteractionDNAJB8 interactions

ZBTB20 ERF DNAJB2 CAPRIN1

5.57e-0480954int:DNAJB8
InteractionDNAI2 interactions

RIN1 ERF RGL3 CCND1

5.57e-0480954int:DNAI2
InteractionLINC02370 interactions

MAP1A PDE4DIP

6.04e-048952int:LINC02370
InteractionZBTB45 interactions

ZBTB20 BACH2

6.04e-048952int:ZBTB45
InteractionSERPINH1 interactions

NRBP2 ZEB1 BRCA1 MAP1B CUL7 ZRANB1 JMY

6.14e-04306957int:SERPINH1
InteractionZNF408 interactions

CHAF1A PDE4DIP CUL7 LRP1B ZRANB1

6.20e-04145955int:ZNF408
InteractionNCOA1 interactions

NCOR1 THRA BRCA1 CCND1 FAM131B

6.40e-04146955int:NCOA1
InteractionD2HGDH interactions

ERF RGL3 DOCK7 GIGYF2 CUL7

6.40e-04146955int:D2HGDH
InteractionSEC61A1 interactions

ASXL1 MAP1B ROR2 CUL7 ZRANB1 CAPRIN1

6.57e-04223956int:SEC61A1
InteractionPFN1 interactions

BRCA1 MAP1A DOCK8 DOCK7 CUL7 DNMBP ZRANB1 JMY WDR44

6.69e-04509959int:PFN1
InteractionARRDC3 interactions

RAD18 MAP1B DOCK7 CUL7 CD320 ZRANB1

6.73e-04224956int:ARRDC3
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

NCOR1 BRCA1 MAP1B CNST PHACTR4

1.54e-04181515694
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASGRF1 RASGRF2 DNMBP

8.54e-0466513722
GeneFamilyT-boxes

TBX3 TBX6

1.16e-0318512766
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASGRF1 RASGRF2 OSBPL5 SH2B2

2.69e-03206514682
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

NCOR1 ASXL1 ZEB1 KMT2B BRCA1 DOCK8 PHACTR4 MAST2 PCM1

1.97e-08180959M8239
CoexpressionGSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN

PIK3AP1 ASXL1 RAD18 ZEB1 CRACDL BACH2 TBX6

8.49e-06200957M291
CoexpressionGSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_DN

KPNA4 ZBTB20 THRA PATJ SUCO ZRANB1 JMY

8.49e-06200957M9260
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

USP6 ASXL1 ZEB1 ZBTB20 BRCA1 MAP1B GIGYF2 CCND1 MAST2 WDR37 DNMBP SUCO DEK

1.29e-058569513M4500
CoexpressionNAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN

KPNA4 AREL1 ZEB1 CNST BACH2 RNF19B CASP3 GIGYF2 SUCO ZRANB1 JMY

3.58e-056809511M41089
CoexpressionKAUFFMANN_MELANOMA_RELAPSE_UP

RAD18 BRCA1 CHAF1A DEK

7.21e-0561954M2431
CoexpressionGSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_DN

PIK3AP1 TXLNB RGL3 R3HCC1 EDC4 JMY

7.66e-05194956M7568
CoexpressionGSE8515_IL1_VS_IL6_4H_STIM_MAC_DN

ADRA2B SCN5A SRCAP SH2B2 CCDC144A TBX6

7.66e-05194956M5767
CoexpressionNUYTTEN_EZH2_TARGETS_DN

CEP68 RAD18 NRXN3 BRCA1 DOCK8 RGL3 CHAF1A CCND1 CD320 CLSPN PATJ FAM131B RNF182

8.13e-0510239513M17122
CoexpressionGSE11057_CD4_CENT_MEM_VS_PBMC_UP

ASXL1 RASGRF2 CNST EDC4 PATJ TECPR1

8.57e-05198956M3116
CoexpressionGSE360_DC_VS_MAC_L_MAJOR_DN

ZBTB20 BRCA1 PHACTR4 SCN5A FAM131B CCDC144A

8.81e-05199956M5182
CoexpressionGSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_DN

PIK3AP1 BRCA1 RGL3 CASP3 DAXX POPDC2

9.05e-05200956M9341
CoexpressionGSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN

PARP4 ZBTB20 THRA RASGRF2 GIGYF2 TECPR1

9.05e-05200956M9765
CoexpressionGSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP

CEP68 ZEB1 PDE4DIP PIP4K2C DNMBP SH2B2

9.05e-05200956M8484
CoexpressionGSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_UP

CNST BACH2 PATJ WDR37 SUCO ZRANB1

9.05e-05200956M9258
CoexpressionBENPORATH_CYCLING_GENES

ASXL1 RAD18 BRCA1 CHAF1A FLAD1 CASP3 CCND1 CLSPN PATJ HORMAD1

1.22e-046489510M8156
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

PIK3AP1 TBX3 ADRA2B IRS4 COL15A1 DMRT2 RASGRF1 RASGRF2 DOCK8 ROR2 SCN5A CCND1 CLSPN

1.32e-0410749513M1941
CoexpressionGSE13173_UNTREATED_VS_IL12_TREATED_ACT_CD8_TCELL_DN

PHACTR4 PDE4DIP CASP3 DNAJB2 DEK

1.65e-04141955M465
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_500

NCOR1 ZBTB20 MAP1B RASGRF1 DOCK8 CASP3 GIGYF2 CAPRIN1 JMY

2.71e-07201949gudmap_developingKidney_e15.5_500_k3
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_500

NCOR1 ZBTB20 MAP1B RASGRF1 DOCK8 CASP3 GIGYF2 CCND1 PATJ CAPRIN1 JMY

1.65e-064029411gudmap_developingKidney_e15.5_anlage of loop of Henle_500
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000

KPNA4 NCOR1 ZBTB20 COL15A1 MAP1B RASGRF1 DOCK8 CASP3 GIGYF2 CCND1 PATJ DNMBP SUCO CAPRIN1 JMY

2.06e-067959415gudmap_developingKidney_e15.5_anlage of loop of Henle_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

TBX3 IRS4 MAP1B SRGAP1 CRACDL BACH2 ROR2 CASP3 GIGYF2 PATJ CAPRIN1 JMY PDZD2

5.43e-058069413gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500

NRXN3 ZBTB20 BRCA1 MAP1A MAP1B NRXN2 CHAF1A DYNC2I1 CLSPN DEK

6.57e-054939410Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000

RAD18 RASGRF2 CASP3 GIGYF2 DNMBP SUCO CAPRIN1 JMY

1.31e-04339948gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_1000

TBX3 ZBTB20 RASGRF2 DOCK8 RGL3 CASP3 GIGYF2 PATJ SRCAP SUCO CAPRIN1 JMY

1.56e-047749412gudmap_developingKidney_e15.5_cortic collect duct_1000
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 MAP1B NRXN2 RASGRF1 EXPH5 IL20RB PATJ

1.93e-071939575fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellmild_COVID-19-B_cell|World / disease group, cell group and cell class (v2)

ZEB1 RASGRF1 ZNF285 JMY PDZD2 TBX6

6.39e-071439564698cc877dda9b1ef7d6f18c9adc869ef791b1d8
ToppCellmild_COVID-19_(asymptomatic)-CD8+_T_naive|World / disease group, cell group and cell class (v2)

RAD18 ZEB1 TXLNB CFAP36 PATJ TBX6

9.13e-07152956f944743f40ff6ed3a7a096dd53e12d3526c67c4d
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TBX3 BRCA1 CHAF1A EDC4 MAST2 DNMBP

1.64e-0616895694cded2e953c0970bf2f3dbe0ce46bd77a5ed8c7
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 MAP1B NRXN2 EXPH5 IL20RB PATJ

2.95e-06186956d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 MAP1B NRXN2 EXPH5 IL20RB PATJ

3.23e-06189956f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZEB1 COL15A1 MAP1B SCN5A POPDC2 PDZD2

3.33e-06190956918ad5037881212008f9f69d5df5da91fd01422c
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ZEB1 ZBTB20 COL15A1 DOCK8 SRGAP1 LRP1B

3.54e-06192956d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCellMS-Treg-exh_CD4|MS / Condition, Cell_class and T cell subcluster

FOCAD CNST PDE4DIP DOCK7 HPS5 WDR37

3.54e-06192956c6722bf142c84ccedd99c1a3344085aecb4cbab4
ToppCellMatrixFB-Fibroblast-B_(Myofibroblast)|MatrixFB / shred on cell class and cell subclass (v4)

TBX3 ZEB1 NRXN3 COL15A1 MAP1B BACH2

3.99e-0619695638ea0eaf42f95c321ca23570d0d7752980cf00f8
ToppCellNon-neuronal-Dividing-IPC-IPC-new|World / Primary Cells by Cluster

ZEB1 ZBTB20 BRCA1 CCND1 CLSPN DEK

4.23e-0619895611d2d4d179bc31ef2897d7ceeaf9bed1b20cbdc0
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBX3 NRXN3 COL15A1 MAP1B NRXN2 SCN5A

4.23e-0619895652ddc1f1ed4ac4c3bac794c90b8feb03e3c221c4
ToppCellNon-neuronal-Dividing-IPC-IPC-new-9|World / Primary Cells by Cluster

ZEB1 ZBTB20 BRCA1 CCND1 CLSPN DEK

4.23e-06198956c724ef958e14e17a7d8c02b9f842510c0780f635
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

NRXN3 THRA MAP1B NRXN2 BACH2 PDE4DIP

4.48e-06200956bad32a95b759fad509401b07bc96a56687c2a592
ToppCellmild-CD8+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CEP68 ZEB1 ZBTB20 RASGRF2 BACH2 PCM1

4.48e-06200956c825320599a61a4c629d736f5c0fd6f1f405540a
ToppCellmild_COVID-19_(asymptomatic)-CD8+_T_naive|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ZEB1 TXLNB CFAP36 PATJ TBX6

2.05e-05155955e2c901d5c9e42d25d7702e5e8fc19b06f7c817be
ToppCellControl|World / group, cell type (main and fine annotations)

NRXN3 ZBTB20 EXPH5 PATJ PDZD2

3.02e-05168955a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell368C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ZEB1 COL15A1 MAP1A CHAF1A DNAAF1

3.29e-05171955f3bf5805823d5733b58742172e7668725ce82931
ToppCell368C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZEB1 COL15A1 MAP1A CHAF1A NME8

3.29e-05171955714a0b0d0c9886fef64170cf53eb64f0d8a47280
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ADRA2B RASGRF1 RRP15 PATJ SRCAP

3.57e-05174955a1f745962a104c6f4b86b7e482da8755384c773a
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBX3 NRXN3 MAP1B POPDC2 TBX6

3.57e-05174955c529f3674b784f872f4387ffdeb46aecb619976b
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ADRA2B RASGRF1 RRP15 PATJ SRCAP

3.67e-0517595578a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RASGRF2 EXPH5 CRACDL CCDC144A PDZD2

3.77e-0517695507abf29d681abdd6c7cc87f9eaf9377e92ce212c
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB20 COL15A1 TXLNB GPBP1 PCM1

3.77e-05176955749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RASGRF2 EXPH5 CRACDL CCDC144A PDZD2

3.98e-051789555d6297f34e104bacefb25c4e2338b50fe13dd19a
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 COL15A1 MAP1B NRXN2 RNF182

4.31e-05181955098dbb3e0ff531c9720a233123250c1e39a97d4c
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

ADRA2B ZEB1 MAP1B RGL3 PDZD2

4.54e-05183955273db6a3b00a93ca852498471187b642b5368185
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RASGRF2 EXPH5 CRACDL CCDC144A PDZD2

4.54e-051839551645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL15A1 BRCA1 CCND1 CD320 CLSPN

4.66e-05184955fa38d6a8709f520a027ad7e3ff783c84187ec467
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

CEP68 ASXL1 PARP4 COL15A1 DNMBP

5.16e-0518895514bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZEB1 COL15A1 MAP1A MAP1B ROR2

5.29e-0518995563449d9f1e78ff2bc8786eb88a0d177fe30c7f4d
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RAD18 BRCA1 CHAF1A CLSPN MAST2

5.43e-05190955d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell(04)_Pre-ciliated|World / shred by cell type and Timepoint

MAP1A CFAP36 CHAF1A DNAAF1 MAST2

5.56e-0519195537cf121e6e80760c8519075b7845b9029958a988
ToppCellT_cells-Central_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

CEP68 RASGRF2 CFAP36 BACH2 PATJ

5.56e-0519195525dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 NRXN2 RASGRF1 RASGRF2 CRACDL

5.84e-05193955be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 NRXN2 RASGRF1 RASGRF2 CRACDL

5.84e-051939550c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 NRXN2 RASGRF1 RASGRF2 CRACDL

5.84e-051939558689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZEB1 COL15A1 MAP1B RASGRF2 ROR2

5.84e-051939555de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZEB1 ZBTB20 NRXN2 CLSPN DEK

5.99e-051949557a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBX3 CHAF1A CCND1 CLSPN DEK

5.99e-05194955ae6d5cf4c825b29e677296df2c0985431c83b82e
ToppCell(7)_MNP-(7)_DC_1|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ZEB1 PDE4DIP CCND1 HPS5 FAM131B

5.99e-051949558dbe0188e2af6f14b3b44e5213fbdd581128082f
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

DNAJC14 RASGRF1 RGL3 R3HCC1 PIP4K2C

5.99e-051949554c40d6b50675eae52c419d69e719a9223df02ae3
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

DNAJC14 RASGRF1 RGL3 R3HCC1 PIP4K2C

5.99e-0519495599a90de637e3babec2131cdd9f05ea965d8a8f30
ToppCellBronchus_Control_(B.)-Epithelial-TX-AT2-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

TBX3 ADRA2B LRP1B FAM131B PDZD2

5.99e-051949555bfc26668fa8f109f2ebc0d5fd98ab5bd219e62c
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RAD18 BRCA1 CHAF1A CLSPN DEK

6.14e-05195955b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZEB1 ZBTB20 BACH2 JMY PCM1

6.14e-05195955ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RAD18 BRCA1 CHAF1A CLSPN DEK

6.14e-0519595556d8734d020b3da08a5aa9e67999706a9e023a99
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RAD18 BRCA1 CHAF1A CLSPN DEK

6.29e-05196955df366d76ea55f49e349d622effa57c1535df8400
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBX3 ZEB1 COL15A1 MAP1B ROR2

6.44e-0519795544673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

ZEB1 ERF MAP1B DYNC2I1 CLSPN

6.44e-051979550fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Cortical_neuron|3m / Sample Type, Dataset, Time_group, and Cell type.

THRA MAP1B SRGAP1 BACH2 RNF182

6.92e-05200955c248233b004f8ef0bab3c65ecfe295887966f2ee
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

ZEB1 ZBTB20 BRCA1 CLSPN DEK

6.92e-052009554923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

THRA MAP1B SRGAP1 BACH2 RNF182

6.92e-05200955e4f0bb57be1112869c7068d0a789c2b802a442dd
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

NCOR1 NRXN3 ZBTB20 DOCK8 PDE4DIP

6.92e-05200955e16bde12326f0cfc4d03f9307cba0e21ea2389cb
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

ZEB1 ZBTB20 BRCA1 CLSPN DEK

6.92e-05200955dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Intermediate|10w / Sample Type, Dataset, Time_group, and Cell type.

CEP68 CRACDL SCN5A DOCK7 DNMBP

6.92e-05200955e5a8647c47a49c8c90c78d681193946de103d8ff
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

NRXN3 MAP1B NRXN2 PDE4DIP WDR44

6.92e-05200955c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBX3 ZEB1 COL15A1 MAP1B ROR2

6.92e-0520095558b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal-Unfolded_protein_responsible_cell|GW23 / Sample Type, Dataset, Time_group, and Cell type.

COPG1 OSBPL5 CD320 DNAAF1

8.15e-051079547fee0193ee02e9cc62f506660ea7ec23fb4d0c84
ToppCellCOVID-19_Mild-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

MAP1A EXPH5 CFAP36 ZNF285

1.35e-041229542aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Neuronal-Neurons|GW08 / Sample Type, Dataset, Time_group, and Cell type.

CCDC82 SRGAP1 CD320

1.57e-044995346185fc61778d7a07f0eabaa934709e1b853dcf5
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TBX3 BACH2 ROR2 SCN5A

3.14e-04152954621e9b33cd3bb1c7b7d0633069f286b203e3d9c0
ToppCellremission-unassigned|remission / disease stage, cell group and cell class

TXLNB IL20RB SRCAP HPS5

3.30e-041549544130769829b838cc8a075c87ff6c187f0f507f8b
ToppCellCOVID-CD4-antiviral_CD4|COVID / Condition, Cell_class and T cell subcluster

ZEB1 CFAP36 BACH2 ZNF285

3.38e-041559547e5ae034036fe85915d38a24195501e6d3bcbfb0
ToppCellremission-unassigned|World / disease stage, cell group and cell class

TXLNB IL20RB SRCAP HPS5

3.38e-04155954d81bec894381e3e2d6249a567e8108b8423e5c54
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Interneuron|GW26 / Sample Type, Dataset, Time_group, and Cell type.

NRXN3 ZBTB20 PDE4DIP

3.46e-0464953fefabdf8d72a8f3caf78eb79d759edb475bdb2ad
ToppCellLPS-antiTNF-Endothelial-Mes-Like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLAD1 POPDC2 HORMAD1 TBX6

3.64e-0415895450df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAD18 HPS5 MAST2 RNF182

4.09e-04163954ce07bc424ef99c547588b07f5c8b39ff0773ca9b
ToppCell3'_v3-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Lung / Manually curated celltypes from each tissue

ADRA2B CHAF1A POPDC2 CLSPN

4.09e-0416395447300dec94dc66e965bf71fafff0a9fd24fae968
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 ZEB1 CHAF1A CLSPN

4.19e-041649541592a5becad7e0f3f990f0d7581d75fcfc7da023
ToppCellNS-critical-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAP1A CHAF1A CD320 NME8

4.28e-0416595417d5c4a111d9b5400780bc5e7b93ce2f5d69ceb7
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TBX3 ZEB1 BACH2 ROR2

4.38e-0416695494636dbc039f794c735960c3425e00bdd5523602
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RAD18 BRCA1 CHAF1A CLSPN

4.48e-04167954108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCellThalamus-Macroglia-POLYDENDROCYTE|Thalamus / BrainAtlas - Mouse McCarroll V32

THRA BRCA1 CASP3 JMY

4.48e-041679541e144c03409df94ccd39760842590e8ea7487e29
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP1A MAP1B CLSPN FAM131B

4.48e-04167954784776d1fcc098f84d3c2eca58fa56cb9428f434
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 MAP1B CCND1 RNF182

4.58e-0416895495dc690c1987b05685d36e6bb20eb79308696e30
ToppCell356C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NRBP2 POPDC2 DEK TECPR1

4.69e-041699540425d2580ed325178f522c0093ff4623de6ce7a8
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related|GW23 / Sample Type, Dataset, Time_group, and Cell type.

ZEB1 CCND1 DNAAF1 HPS5

4.69e-0416995429db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RAD18 BRCA1 CHAF1A CLSPN

4.69e-04169954e7514956b2e4298222ec443f98b2f5289451786e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC|GW23 / Sample Type, Dataset, Time_group, and Cell type.

ZEB1 CCND1 DNAAF1 HPS5

4.69e-04169954b1611e61f635f8f9b87250e026ad30999cbee041
ToppCell356C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NRBP2 POPDC2 DEK TECPR1

4.69e-04169954fec669968a77060bd77ee8695034e35a642c984f
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

TXLNB PDE4DIP SCN5A POPDC2

4.79e-041709543f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL15A1 MAP1A SUCO SH2B2

4.79e-04170954c638dfde9ce30190abbe0caea1c3eb874af09857
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRBP2 BRCA1 CHAF1A DEK

4.90e-041719541efce222989460bb59bd9fa955e7d9a60c73994c
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ERF JMY PCM1 CCDC144A

4.90e-041719542e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADRA2B NRXN3 SUCO CCDC144A

5.01e-04172954a03f30a996a9474ad4cccd209476423a042df002
ToppCellNasal_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

USP6 DMRT2 RASGRF2 RNF182

5.01e-0417295404fabb40fa9357d8902f3b04adc15231626cd9f8
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADRA2B NRXN3 SUCO CCDC144A

5.01e-04172954f92a53ad2e464cd68ba1714bcc1d5911479cdf1c
ToppCellNasal_Brush-Epithelial-Ionocytes|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

USP6 DMRT2 RASGRF2 RNF182

5.01e-04172954dd3a23dc78dc6939f41126f8d7bd23a2e4713647
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 NRXN3 COL15A1 SRGAP1

5.01e-04172954073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

EXPH5 CRACDL DOCK7 MAST2

5.12e-04173954b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRCA1 CHAF1A CCND1 CLSPN

5.12e-0417395415af4a0f7516dbf5c93ba66a19aca073ebe30d04
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ASXL1 NRXN3 DMRT2 PDZD2

5.46e-0417695425ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL15A1 NRXN2 ROR2 DYNC2I1

5.46e-04176954fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL15A1 NRXN2 ROR2 DYNC2I1

5.46e-04176954f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_early_1|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

BRCA1 CHAF1A CCND1 CLSPN

5.46e-041769542a15437c5f5dbf6398d5ea70050632c24a7dc66c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RASGRF2 CRACDL CCDC144A PDZD2

5.46e-04176954c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BRCA1 CHAF1A CLSPN DEK

5.46e-04176954cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 MAP1A NRXN2 CCDC144A

5.46e-0417695429b71369503719c74888cd356ceb6724cfdcabd9
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EXPH5 CRACDL DOCK7 PATJ

5.46e-04176954437cfc5e06416bb0fc76d1f9dc106f74e279e880
DrugAcenocoumarol [152-72-7]; Down 200; 11.4uM; MCF7; HT_HG-U133A

ASXL1 KMT2B BRCA1 EXPH5 PDE4DIP RRP15 MAST2

1.66e-051939577232_DN
DrugNaftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; HL60; HT_HG-U133A

EXPH5 PDE4DIP CASP3 CD320 SRCAP MAST2 PCM1

1.83e-051969572974_DN
DrugRamipril [87333-19-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A

CEP68 NCOR1 BRCA1 PHACTR4 PATJ SRCAP PCM1

1.90e-051979576792_DN
DrugDroperidol [548-73-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A

NRXN3 THRA MAP1B RASGRF1 PDE4DIP SRCAP TBX6

1.96e-051989575690_UP
DrugAvermectin B1 [71751-41-2]; Down 200; 4.8uM; MCF7; HT_HG-U133A

ASXL1 BRCA1 PDE4DIP RRP15 PATJ DNAAF1 DNAJB2

1.96e-051989577218_DN
DrugAntipyrine [60-80-0]; Up 200; 21.2uM; HL60; HG-U133A

ASXL1 ZEB1 RNF19B CD320 MAST2 PCM1 WDR44

2.02e-051999571989_UP
Drugestradiol, USP; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

EXPH5 RNF19B R3HCC1 EDC4 PATJ SRCAP DNAJB2

2.09e-05200957988_DN
Diseasecolon cancer (is_implicated_in)

BRCA1 CHAF1A CASP3 LRP1B

5.04e-0636934DOID:219 (is_implicated_in)
Diseasecerebral microbleeds

SRGAP1 OSBPL5 CCND1

2.83e-0519933EFO_0010059
DiseaseLung diseases

ADRA2B DOCK8 DNAAF1 NME8

1.10e-0478934C0024115
Diseaseleptin measurement

NRXN3 PATJ LRP1B PDZD2

1.28e-0481934EFO_0005000
DiseaseProstatic Neoplasms

NCOR1 TBX3 ZBTB20 COL15A1 ERF BRCA1 CCND1 PATJ LRP1B

1.44e-04616939C0033578
DiseaseMalignant neoplasm of prostate

NCOR1 TBX3 ZBTB20 COL15A1 ERF BRCA1 CCND1 PATJ LRP1B

1.44e-04616939C0376358
DiseaseNeoplasm of uncertain or unknown behavior of breast

NCOR1 TBX3 BRCA1

2.96e-0441933C0496956
DiseaseBreast adenocarcinoma

NCOR1 TBX3 BRCA1

2.96e-0441933C0858252
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

NCOR1 GIGYF2 SRCAP

5.03e-0449933DOID:0060037 (implicated_via_orthology)
Diseaseresponse to statin, myopathy

ERICH1 RASGRF2

5.31e-0411932EFO_0004145, GO_0036273
DiseaseMouth Diseases

BRCA1 CHAF1A

6.35e-0412932C0026636
DiseaseCakut

SRGAP1 TBX6

7.49e-0413932C1968949
DiseaseThyroid Diseases

TBX3 CNST

7.49e-0413932C0040128
Diseasecolon cancer (is_marker_for)

BRCA1 CHAF1A CASP3

8.67e-0459933DOID:219 (is_marker_for)
Diseaselung non-small cell carcinoma (is_implicated_in)

BRCA1 CASP3 CCND1 LRP1B

9.95e-04139934DOID:3908 (is_implicated_in)
Diseaseplatelet storage pool deficiency (implicated_via_orthology)

DOCK7 HPS5

1.00e-0315932DOID:2223 (implicated_via_orthology)
Diseasetransitional cell carcinoma (is_marker_for)

CASP3 DAXX CCND1

1.05e-0363933DOID:2671 (is_marker_for)
Diseasestomach cancer (is_marker_for)

TBX3 BRCA1 CASP3 DAXX

1.08e-03142934DOID:10534 (is_marker_for)
Diseasecolorectal mucinous adenocarcinoma

ZBTB20 RASGRF2

1.15e-0316932EFO_0009361
DiseaseMammary Carcinoma, Human

NCOR1 TBX3 ZEB1 BRCA1 CCND1 DEK RNF182

1.38e-03525937C4704874
DiseaseMammary Neoplasms, Human

NCOR1 TBX3 ZEB1 BRCA1 CCND1 DEK RNF182

1.38e-03525937C1257931
DiseaseMammary Neoplasms

NCOR1 TBX3 ZEB1 BRCA1 CCND1 DEK RNF182

1.41e-03527937C1458155
Diseaselevel of Phosphatidylcholine (15:0_18:2) in blood serum

RAD18 DOCK7

1.45e-0318932OBA_2045065
Diseasestomach cancer (is_implicated_in)

BRCA1 CASP3 LRP1B

1.54e-0372933DOID:10534 (is_implicated_in)
DiseaseBreast Carcinoma

NCOR1 TBX3 ZEB1 BRCA1 CCND1 DEK RNF182

1.58e-03538937C0678222
Diseaseatherosclerosis (biomarker_via_orthology)

CASP3 CCND1

1.80e-0320932DOID:1936 (biomarker_via_orthology)
Diseaseobsolete aging

KPNA4 AREL1 RASGRF1 GIGYF2 LRP1B

1.92e-03279935GO_0007568
Diseaselung non-small cell carcinoma (is_marker_for)

IRS4 BRCA1 CASP3 CCND1

2.04e-03169934DOID:3908 (is_marker_for)
DiseaseMalignant neoplasm of breast

NCOR1 TBX3 ZEB1 BRCA1 RASGRF2 CCND1 CLSPN DEK NME8 RNF182

2.06e-0310749310C0006142
Diseasehypothyroidism (biomarker_via_orthology)

NCOR1 MAP1A MAP1B

2.09e-0380933DOID:1459 (biomarker_via_orthology)
Diseaseimpotence (biomarker_via_orthology)

CASP3 CCND1

2.18e-0322932DOID:1875 (biomarker_via_orthology)
DiseaseBronchiectasis

DNAAF1 NME8

2.18e-0322932C0006267
Diseasemedial orbital frontal cortex volume measurement

FOCAD NRXN3

2.81e-0325932EFO_0010315
Diseasebreast cancer (is_marker_for)

THRA KMT2B BRCA1 CASP3

2.83e-03185934DOID:1612 (is_marker_for)
DiseaseIntellectual Disability

ADRA2B BRCA1 MAP1B NRXN2 DOCK8 WDR37

2.94e-03447936C3714756

Protein segments in the cluster

PeptideGeneStartEntry
VSDCSDGTSELEEPL

ERF

186

P50548
CEEDGVDTSEEDPTL

ERICH1

206

Q86X53
EESITLCLSGDEPDA

BACH2

286

Q9BYV9
TTICSGHDADTEDDP

CEP68

141

Q76N32
PDCLTDGSDVVSDLE

CFAP36

136

Q96G28
EGVCGASPEDEAEEE

ADRA2B

286

P18089
TSDHEAEEPDCIISE

DNMBP

341

Q6XZF7
EEEEEVDLACTPTDV

CCND1

276

P24385
IPGCEEEDASEISVS

CCDC144CP

291

Q8IYA2
LSEDEGVTEECADPE

CHAF1A

641

Q13111
GCDSVTDTEPEDEKV

PIK3AP1

146

Q6ZUJ8
TELDCGIETDSGVDD

CASP3

166

P42574
LCEEEEAASAPAVED

CAPRIN1

256

Q14444
GCPSASRAETDDEDD

DAXX

426

Q9UER7
EPEDTADVESCGSNE

ASXL1

101

Q8IXJ9
DEEEVEEDGPSSCSE

R3HCC1

261

Q9Y3T6
EELEPDREEDSSSCI

RAD18

411

Q9NS91
IPEESEDCCEESSPT

EDC4

241

Q6P2E9
ECEELGSDEGEVHTP

KIAA1107

931

Q9UPP5
HCTSPALGEDELEEE

DNAJC14

156

Q6Y2X3
ESEDESDILEESPCG

NRBP2

21

Q9NSY0
DSDESLDTCPEEVEI

LRP1B

61

Q9NZR2
ECPSITAEAALDSDE

MAP1A

2521

P78559
AEEPEEDGEEHVCVS

MAP1B

951

P46821
SPESEDEEEALPCTD

JMY

971

Q8N9B5
EDSENDETCAPLTED

GPBP1

396

Q86WP2
SDGSDEEECRIEPCT

CD320

81

Q9NPF0
EDVSSDTCPKEEDTE

HPS5

581

Q9UPZ3
EVCDGDDDESSNEPE

DYNC2I1

386

Q8WVS4
DISDQEEDEESEGCP

PCM1

1766

Q15154
EDEDHPGSGCSTSEE

PDZD2

886

O15018
VLPEDEDTEECEHLT

CUL7

476

Q14999
DDEDLEECEPSTGGE

NRXN2

1406

Q9P2S2
DDPVDSDCDTDTTTD

EXPH5

1961

Q8NEV8
GCVPEEESSDGESDE

KMT2B

106

Q9UMN6
EGLCPDSATEEEDTV

PARP4

116

Q9UKK3
SDPDSSEACAEEEEG

RGL3

221

Q3MIN7
DDEEEEEQTCPSTFS

PHACTR4

476

Q8IZ21
SLSDLTCTPEEEENE

CRACDL

251

Q6NV74
APEEEEDAGCRDLES

FAM131B

281

Q86XD5
LTEGPECDVTDDITA

IL20RB

91

Q6UXL0
LVASAECPSDDEDLE

NRXN2

351

P58401
DEDLEECEPSTGGEL

NRXN2

361

P58401
SSEENLSSEDEELPC

BRCA1

1211

P38398
KESCPSSDEVDEEEE

CCDC82

266

Q8N4S0
TDDDDDDCGTIDELP

HEATR5B

1451

Q9P2D3
VSDDVVSPDEEGICS

DOCK7

1751

Q96N67
SEDTLSPDEDGVCAG

DOCK8

1706

Q8NF50
DVESLELEEDVCGAP

DMRT2

16

Q9Y5R5
RPVDEGEECSDSEGS

GIGYF2

326

Q6Y7W6
ASCPLDSDLSEDEDL

DNAJB2

241

P25686
KCPEILSDESSSDED

DEK

221

P35659
IPGCEEEDASEISVS

CCDC144B

341

Q3MJ40
DEEDEDSPSECHTPE

AREL1

331

O15033
SCDSPDTPETDDSIE

MAST2

481

Q6P0Q8
CIDDLPDLEDDDETG

DNAAF1

546

Q8NEP3
TVKDCDPTTGETDDE

COPG1

731

Q9Y678
SSELEEPSLVCEEDE

HORMAD1

286

Q86X24
IPGCEEEDASEISVS

CCDC144A

341

A2RUR9
TLDSEEEGPLEECLA

FLAD1

326

Q8NFF5
PEELCDPEESSASGE

COL15A1

231

P39059
GPDSSEDACEDDSRL

CNST

386

Q6PJW8
STALEDCISVDEEGP

FOCAD

361

Q5VW36
PVREDESEVDGDCSL

PIP4K2C

301

Q8TBX8
TPESCPELSDEEQDG

OSBPL5

781

Q9H0X9
SESEEEDLPVGEEVC

IRS4

66

O14654
EATEEAEEGEHRTPC

TSGA10IP

251

Q3SY00
LQEVDCGSPSSSEEE

RIN1

311

Q13671
DAQSDDVPDITSDEC

RNF19B

671

Q6ZMZ0
DAGTEPHTSEDECEP

SRGAP1

731

Q7Z6B7
KDLCPSEGESDAEAE

TBX3

366

O15119
DCTLIEEPDASDDDS

RASGRF2

526

O14827
SSDDEDFVECEPSTG

NRXN3

316

Q9HDB5
ATCSADEDVDGEPER

NCOR1

881

O75376
TEECGEDRLPKSDSE

SCN5A

486

Q14524
EEGSVPETELLGDCD

ROR2

916

Q01974
PEDTAESQASDELEC

RNF182

6

Q8N6D2
DEDEVDANSSDCEPE

SRCAP

466

Q6ZRS2
IDCTLLEEPESTEEE

RASGRF1

521

Q13972
CSGSFPTDKEEEDEE

CLSPN

981

Q9HAW4
VDSDSEVSEESPCES

NME8

136

Q8N427
TDTCELPEREEGEGE

PATJ

1041

Q8NI35
GRTAEDTVEDACPAE

TECPR1

451

Q7Z6L1
TDTGVCSGTDEDPDD

WDR44

576

Q5JSH3
ESEKGDEEVCEPAVS

POPDC2

281

Q9HBU9
DPGDSEEDTELSCTR

SH2B2

306

O14492
CDSTLGGDIRESDPE

TBX6

311

O95947
DAIEADSEGDAEPCD

RRP15

61

Q9Y3B9
PSETEQSETDCDVGE

SUCO

161

Q9UBS9
CTEDTDQAEGTESEP

ZBTB20

356

Q9HC78
SVTDAADCEGVPEDD

ZEB1

46

P37275
CSDKDEPDLDGDVSS

WDR37

251

Q9Y2I8
EADSPSSSEEEPEVC

THRA

466

P10827
SSSEEEPEVCEDLAG

THRA

471

P10827
DCEETTEEAGREPVA

TXLNB

101

Q8N3L3
EECSPHLEDVSLSEE

ZNF285

96

Q96NJ3
SSCEELHPDEIDTDS

USP6

1346

P35125
RPCTSLSDGEEDEDD

ZRANB1

691

Q9UGI0
VPHEDICEDSDIDGD

KPNA4

51

O00629
EAEREETTSPECEEH

PDE4DIP

1286

Q5VU43