Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-11	6.20e-08	11	216	5	GO:0004523
GeneOntologyMolecularFunction	low-affinity D-glucose:sodium symporter activity	SLC5A9 SLC5A2 SLC5A4	1.25e-06	3	216	3	GO:0005362
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 NYNRIN POP1 ERVK-11	2.63e-06	37	216	6	GO:0016891
GeneOntologyMolecularFunction	hexose transmembrane transporter activity	SLC2A7 SLC5A9 SLC2A5 SLC5A2 SLC5A4	6.30e-06	25	216	5	GO:0015149
GeneOntologyMolecularFunction	D-glucose transmembrane transporter activity	SLC2A7 SLC5A9 SLC2A5 SLC5A2 SLC5A4	6.30e-06	25	216	5	GO:0055056
GeneOntologyMolecularFunction	monosaccharide transmembrane transporter activity	SLC2A7 SLC5A9 SLC2A5 SLC5A2 SLC5A4	9.40e-06	27	216	5	GO:0015145
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 NYNRIN POP1 ERVK-11	9.76e-06	46	216	6	GO:0016893
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11	1.22e-05	14	216	4	GO:0003964
GeneOntologyMolecularFunction	sugar transmembrane transporter activity	SLC2A7 SLC5A9 SLC2A5 SLC5A2 SLC5A4	1.36e-05	29	216	5	GO:0051119
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ERVK-6 CDK16 CDK17 EPHA6 ERVK-7 ERVK-10 LMTK3 CDKL1 PASK PIK3C2G PIK3CD MAP3K9 ERVK-11 ROCK2 KALRN POLM RIPK4 PAPSS1 ULK3 NEK8 GYS2 EPHA10 MVK SBK3 CDK6	3.06e-05	938	216	25	GO:0016772
GeneOntologyMolecularFunction	D-glucose:sodium symporter activity	SLC5A9 SLC5A2 SLC5A4	4.23e-05	7	216	3	GO:0005412
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-18 ERVK-25	4.65e-05	37	216	5	GO:0004190
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11 POLM	5.31e-05	38	216	5	GO:0034061
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-18 ERVK-25	5.31e-05	38	216	5	GO:0070001
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-11	6.90e-05	21	216	4	GO:0035613
GeneOntologyMolecularFunction	carbohydrate transmembrane transporter activity	SLC2A7 SLC5A9 SLC2A5 SLC5A2 SLC5A4	8.68e-05	42	216	5	GO:0015144
GeneOntologyMolecularFunction	protein serine kinase activity	CDK16 CDK17 LMTK3 CDKL1 PASK MAP3K9 ROCK2 KALRN RIPK4 ULK3 NEK8 SBK3 CDK6	1.72e-04	363	216	13	GO:0106310
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-7 ERVK-10 NYNRIN POP1 ERVK-11	2.15e-04	79	216	6	GO:0004521
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDK16 CDK17 EPHA6 LMTK3 CDKL1 PASK PIK3C2G PIK3CD MAP3K9 ROCK2 KALRN RIPK4 PAPSS1 ULK3 NEK8 EPHA10 MVK SBK3 CDK6	2.68e-04	709	216	19	GO:0016773
GeneOntologyMolecularFunction	cyclin-dependent protein serine/threonine kinase activity	CDK16 CDK17 CDKL1 CDK6	2.93e-04	30	216	4	GO:0004693
GeneOntologyMolecularFunction	cyclin-dependent protein kinase activity	CDK16 CDK17 CDKL1 CDK6	2.93e-04	30	216	4	GO:0097472
GeneOntologyMolecularFunction	kinase activity	CDK16 CDK17 EPHA6 LMTK3 CDKL1 PASK PIK3C2G PIK3CD MAP3K9 ROCK2 KALRN RIPK4 PAPSS1 ULK3 NEK8 EPHA10 MVK SBK3 CDK6	6.68e-04	764	216	19	GO:0016301
GeneOntologyMolecularFunction	carbohydrate:monoatomic cation symporter activity	SLC5A9 SLC5A2 SLC5A4	7.59e-04	17	216	3	GO:0005402
GeneOntologyMolecularFunction	HLA-A specific inhibitory MHC class I receptor activity	LILRB2 LILRA2	1.14e-03	5	216	2	GO:0030107
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CDK16 CDK17 LMTK3 CDKL1 PASK MAP3K9 ROCK2 KALRN RIPK4 ULK3 NEK8 SBK3 CDK6	1.19e-03	446	216	13	GO:0004674
GeneOntologyMolecularFunction	HLA-B specific inhibitory MHC class I receptor activity	LILRB2 LILRA2	1.70e-03	6	216	2	GO:0030109
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-11	1.35e-07	13	213	5	GO:0015074
Domain	Kinase-like_dom	CDK16 CDK17 EPHA6 CDKL1 PASK DST PIK3C2G PIK3CD MAP3K9 ROCK2 KALRN ACAD10 RIPK4 ULK3 NEK8 MACF1 EPHA10 SBK3 CDK6	1.25e-05	542	210	19	IPR011009
Domain	APC_su10/DOC_dom	CUL9 HERC2 HECTD3	4.74e-05	7	210	3	IPR004939
Domain	DOC	CUL9 HERC2 HECTD3	4.74e-05	7	210	3	PS51284
Domain	ANAPC10	CUL9 HERC2 HECTD3	4.74e-05	7	210	3	PF03256
Domain	APC10	CUL9 HERC2 HECTD3	4.74e-05	7	210	3	SM01337
Domain	Na/solute_symporter_CS	SLC5A9 SLC5A2 SLC5A4	7.53e-05	8	210	3	IPR018212
Domain	Spectrin	DST KALRN SPTBN4 MACF1	1.16e-04	23	210	4	PF00435
Domain	LRDF	LEFTY2 LEFTY1	1.26e-04	2	210	2	IPR003942
Domain	Fru_transpt_5	SLC2A7 SLC2A5	1.26e-04	2	210	2	IPR002442
Domain	NA_SOLUT_SYMP_1	SLC5A9 SLC5A2 SLC5A4	2.16e-04	11	210	3	PS00456
Domain	PROTEIN_KINASE_ATP	CDK16 CDK17 EPHA6 LMTK3 CDKL1 PASK MAP3K9 ROCK2 KALRN RIPK4 ULK3 NEK8 EPHA10 SBK3 CDK6	2.26e-04	459	210	15	PS00107
Domain	SSF	SLC5A9 SLC5A2 SLC5A4	2.86e-04	12	210	3	PF00474
Domain	NA_SOLUT_SYMP_2	SLC5A9 SLC5A2 SLC5A4	2.86e-04	12	210	3	PS00457
Domain	Na/solute_symporter	SLC5A9 SLC5A2 SLC5A4	2.86e-04	12	210	3	IPR001734
Domain	NA_SOLUT_SYMP_3	SLC5A9 SLC5A2 SLC5A4	2.86e-04	12	210	3	PS50283
Domain	Spectrin_repeat	DST KALRN SPTBN4 MACF1	2.96e-04	29	210	4	IPR002017
Domain	Cul7	CUL9 HERC2	3.75e-04	3	210	2	PF11515
Domain	CPH_domain	CUL9 HERC2	3.75e-04	3	210	2	IPR021097
Domain	SPEC	DST KALRN SPTBN4 MACF1	4.36e-04	32	210	4	SM00150
Domain	Spectrin/alpha-actinin	DST KALRN SPTBN4 MACF1	4.36e-04	32	210	4	IPR018159
Domain	PROTEIN_KINASE_DOM	CDK16 CDK17 EPHA6 LMTK3 CDKL1 PASK MAP3K9 ROCK2 KALRN RIPK4 ULK3 NEK8 EPHA10 SBK3 CDK6	4.81e-04	493	210	15	PS50011
Domain	Ser/Thr_kinase_AS	CDK16 CDK17 CDKL1 PASK MAP3K9 ROCK2 KALRN RIPK4 ULK3 NEK8 SBK3 CDK6	7.49e-04	357	210	12	IPR008271
Domain	PROTEIN_KINASE_ST	CDK16 CDK17 CDKL1 PASK MAP3K9 ROCK2 KALRN RIPK4 ULK3 NEK8 SBK3 CDK6	8.46e-04	362	210	12	PS00108
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	MUC21 POGLUT3 EPHA6 TNFRSF6B PGLYRP2 DPEP2 NBEAL2 SPACA6 IGSF9 CHPF2 FLRT3 IL27RA DNHD1 ALKBH7 CFAP36 ADAM12 DIPK2B TMEM25 LEFTY1 CDH24 IL17RE GHITM LGR6 SUFU	1.85e-08	985	219	24	12975309
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PEX6 CUL9 CARD10 ABCA7 DST KCNG1 PIK3CD NBEAL2 HERC2 DPH2 ARHGEF19 KALRN AMBRA1 C2CD2 KIFC2 ARHGEF10L CELSR2 MEGF8 MROH6 ADAMTS7 IL17RE NEK8 NUP188 SUFU HCFC1	3.88e-08	1105	219	25	35748872
Pubmed	A family of human cdc2-related protein kinases.	CDK16 CDK17 CDKL1 CDK6	1.05e-07	8	219	4	1639063
Pubmed	Lefty-1 inhibits renal epithelial-mesenchymal transition by antagonizing the TGF-β/Smad signaling pathway.	TGFB1 LEFTY2 LEFTY1	2.46e-07	3	219	3	32065356
Pubmed	Lefty-1 alleviates TGF-β1-induced fibroblast-myofibroblast transdifferentiation in NRK-49F cells.	TGFB1 LEFTY2 LEFTY1	2.46e-07	3	219	3	26316705
Pubmed	Lefty1 alleviates renal tubulointerstitial injury in mice with unilateral ureteral obstruction.	TGFB1 LEFTY2 LEFTY1	2.46e-07	3	219	3	26647776
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10	9.81e-07	4	219	3	10469592
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-18	2.44e-06	5	219	3	12629516
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-10 ERVK-18 ERVK-25 ERVK-11	4.37e-06	18	219	4	18664271
Pubmed	Bacterial c-di-GMP affects hematopoietic stem/progenitors and their niches through STING.	IRF3 STING1 TGFB1	1.35e-05	8	219	3	25843711
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ILF2 NOL6 CUL9 DDB1 DST NUP210 POP1 HERC2 NIPBL MOV10 MACF1 SCAF11 NUP188 LTF HCFC1	1.92e-05	653	219	15	22586326
Pubmed	Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling.	IRF3 STING1 SIRPG	2.86e-05	10	219	3	28801234
Pubmed	Visceral endoderm mediates forebrain development by suppressing posteriorizing signals.	SIX3 LEFTY2 LEFTY1	2.86e-05	10	219	3	10985852
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-10 ERVK-18 ERVK-25 ERVK-11	2.99e-05	94	219	6	21542922
Pubmed	Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function.	MAG GRIN2A LEFTY2 LEFTY1	3.69e-05	30	219	4	27568567
Pubmed	CRL4AMBRA1 is a master regulator of D-type cyclins.	DDB1 LRRC41 AMBRA1 CDK6	3.69e-05	30	219	4	33854235
Pubmed	Myelin suppresses axon regeneration by PIR-B/SHP-mediated inhibition of Trk activity.	MAG LILRB2 LILRA2	3.91e-05	11	219	3	21364532
Pubmed	Protein tyrosine phosphatase SHP-1 positively regulates TLR-induced IL-12p40 production in macrophages through inhibition of phosphatidylinositol 3-kinase.	LILRB2 SIRPG LILRA2	3.91e-05	11	219	3	20145200
Pubmed	PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly.	SIX3 LEFTY2 LEFTY1	3.91e-05	11	219	3	31950080
Pubmed	The disintegrin and metalloproteinase ADAM12 contributes to TGF-beta signaling through interaction with the type II receptor.	ADAM12 TGFB1	3.95e-05	2	219	2	17620406
Pubmed	Inhibition of IRF3 expression reduces TGF-β1-induced proliferation of hepatic stellate cells.	IRF3 TGFB1	3.95e-05	2	219	2	26611114
Pubmed	LEFTY2 alleviates hepatic stellate cell activation and liver fibrosis by regulating the TGF-β1/Smad3 pathway.	LEFTY2 LEFTY1	3.95e-05	2	219	2	32745796
Pubmed	Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.	IRF3 STING1	3.95e-05	2	219	2	27302953
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	3.95e-05	2	219	2	11002341
Pubmed	STING-associated vasculopathy develops independently of IRF3 in mice.	IRF3 STING1	3.95e-05	2	219	2	28951494
Pubmed	LEFTY, a member of the transforming growth factor-beta superfamily, inhibits uterine stromal cell differentiation: a novel autocrine role.	LEFTY2 LEFTY1	3.95e-05	2	219	2	20056823
Pubmed	Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.	LEFTY2 LEFTY1	3.95e-05	2	219	2	10053005
Pubmed	Mutation analysis of human LEFTY A and LEFTY B genes in children with Ivemark syndrome.	LEFTY2 LEFTY1	3.95e-05	2	219	2	11100524
Pubmed	Mitochondrial DNA and the STING pathway are required for hepatic stellate cell activation.	STING1 TGFB1	3.95e-05	2	219	2	37013923
Pubmed	Analyses of the Genetic Polymorphisms rs3740199 and rs1871054 of the ADAM12 Gene and the Alleles at the rs2073508 Loci of the TGFB1 Gene and Their Contribution to Susceptibility to Primary Knee Osteoarthritis.	ADAM12 TGFB1	3.95e-05	2	219	2	32250658
Pubmed	STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.	IRF3 STING1	3.95e-05	2	219	2	24052526
Pubmed	MITA modulated autophagy flux promotes cell death in breast cancer cells.	IRF3 STING1	3.95e-05	2	219	2	28366813
Pubmed	Lefty1 and lefty2 control the balance between self-renewal and pluripotent differentiation of mouse embryonic stem cells.	LEFTY2 LEFTY1	3.95e-05	2	219	2	24147624
Pubmed	Lefty antagonises TGF-beta1 induced epithelial-mesenchymal transition in tubular epithelial cells.	LEFTY2 LEFTY1	3.95e-05	2	219	2	20171171
Pubmed	Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily.	LEFTY2 LEFTY1	3.95e-05	2	219	2	9496783
Pubmed	A functional role of LEFTY during progesterone therapy for endometrial carcinoma.	LEFTY2 LEFTY1	3.95e-05	2	219	2	29268772
Pubmed	RNF39 facilitates antiviral immune responses by promoting K63-linked ubiquitination of STING.	STING1 RNF39	3.95e-05	2	219	2	39255680
Pubmed	Lefty1 Ameliorates Post-infarction Fibrosis by Suppressing p-Smad2 and p-ERK1/2 Signaling Pathways.	LEFTY2 LEFTY1	3.95e-05	2	219	2	33409963
Pubmed	LEFTY2 inhibits endometrial receptivity by downregulating Orai1 expression and store-operated Ca2+ entry.	LEFTY2 LEFTY1	3.95e-05	2	219	2	29230527
Pubmed	Molecular analysis of LEFTY-expressing cells in early human embryoid bodies.	LEFTY2 LEFTY1	3.95e-05	2	219	2	17038673
Pubmed	MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP.	IRF3 STING1	3.95e-05	2	219	2	21813776
Pubmed	STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3.	IRF3 STING1	3.95e-05	2	219	2	31121492
Pubmed	Decreased Expressions of STING but not IRF3 Molecules in Chronic HBV Infected Patients.	IRF3 STING1	3.95e-05	2	219	2	26058929
Pubmed	RCCD1 depletion attenuates TGF-β-induced EMT and cell migration by stabilizing cytoskeletal microtubules in NSCLC cells.	RCCD1 TGFB1	3.95e-05	2	219	2	28455245
Pubmed	Anti-inflammatory effects of Lefty-1 in renal tubulointerstitial inflammation via regulation of the NF-κB pathway.	LEFTY2 LEFTY1	3.95e-05	2	219	2	29286065
Pubmed	Role of TGF-β in a mouse model of high turnover renal osteodystrophy.	TGFB1 NEK8	3.95e-05	2	219	2	24166835
Pubmed	Isolation, characterization, and function of EBAF/LEFTY B: role in infertility.	LEFTY2 LEFTY1	3.95e-05	2	219	2	21401636
Pubmed	RHCG suppresses cervical cancer progression through inhibiting migration and inducing apoptosis regulated by TGF-β1.	RHCG TGFB1	3.95e-05	2	219	2	29852177
Pubmed	Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease.	IRF3 STING1	3.95e-05	2	219	2	29106945
Pubmed	Yersinia YopJ negatively regulates IRF3-mediated antibacterial response through disruption of STING-mediated cytosolic DNA signaling.	IRF3 STING1	3.95e-05	2	219	2	27742471
Pubmed	Proteomic identification of ADAM12 as a regulator for TGF-β1-induced differentiation of human mesenchymal stem cells to smooth muscle cells.	ADAM12 TGFB1	3.95e-05	2	219	2	22808268
Pubmed	Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.	ERVK-6 ERVK-18	3.95e-05	2	219	2	11672541
Pubmed	Lefty is expressed in mouse endometrium in estrous cycle and peri-implantation period.	LEFTY2 LEFTY1	3.95e-05	2	219	2	15640253
Pubmed	The STING in the tail for cytosolic DNA-dependent activation of IRF3.	IRF3 STING1	3.95e-05	2	219	2	22394560
Pubmed	Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA.	IRF3 STING1	3.95e-05	2	219	2	23910378
Pubmed	Biological, clinical and population relevance of 95 loci for blood lipids.	LILRB2 NYNRIN MAMSTR CELSR2 MACF1 UBASH3B MVK	4.12e-05	146	219	7	20686565
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ILF2 LMTK3 DDB1 NCDN SIRPG LRIG2 DST HERC2 NIPBL SHANK1 ROCK2 KALRN GRIN2A GRM4 SPTBN4 CELSR2 MACF1 UBASH3B	4.37e-05	963	219	18	28671696
Pubmed	The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis.	SIX3 LEFTY2 LEFTY1	5.20e-05	12	219	3	9671576
Pubmed	UBE2O and USP7 co-regulate RECQL4 ubiquitinylation and homologous recombination-mediated DNA repair.	UIMC1 DDB1 NKAP MOV10 TAF1C MACF1 HCFC1	6.03e-05	155	219	7	34921745
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	VPS33A CUL9 DST HERC2 VARS1 LRRC41 HECTD3 RCCD1	6.42e-05	212	219	8	33853758
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	NOL6 CARD10 OTOP3 HSD11B1L DDB1 NBEAL2 RNASEH2C POLM CFAP36 UFC1 SLC5A2 DIPK2B USP8 NEK8 C11orf21 CERCAM	8.43e-05	832	219	16	36724073
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	POGLUT3 LRIG2 SIAE NUP210 CHPF2 TGFB1 CERCAM	8.60e-05	164	219	7	32409323
Pubmed	The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse.	SIX3 LEFTY2 LEFTY1	1.06e-04	15	219	3	11358868
Pubmed	Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings.	SIX3 LEFTY2 LEFTY1	1.06e-04	15	219	3	17481602
Pubmed	Selective inactivation of Otx2 mRNA isoforms reveals isoform-specific requirement for visceral endoderm anteriorization and head morphogenesis and highlights cell diversity in the visceral endoderm.	SIX3 LEFTY2 LEFTY1	1.06e-04	15	219	3	19615442
Pubmed	Nodal and lefty signaling regulates the growth of pancreatic cells.	LEFTY2 LEFTY1	1.18e-04	3	219	2	18393305
Pubmed	Induction of complementary function reductase enzymes in colon cancer cells by dithiole-3-thione versus sodium selenite.	TXNRD1 PTGR1	1.18e-04	3	219	2	25179160
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	1.18e-04	3	219	2	12399109
Pubmed	Role of asymmetric signals in left-right patterning in the mouse.	LEFTY2 LEFTY1	1.18e-04	3	219	2	11471154
Pubmed	Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and lefty processing.	LEFTY2 LEFTY1	1.18e-04	3	219	2	16141390
Pubmed	Antibodies to a renal Na+/glucose cotransport system localize to the apical plasma membrane domain of polar mouse embryo blastomeres.	SLC5A9 SLC5A2	1.18e-04	3	219	2	1702069
Pubmed	IFT46 plays an essential role in cilia development.	LEFTY2 LEFTY1	1.18e-04	3	219	2	25722189
Pubmed	Distinct transcriptional regulation and phylogenetic divergence of human LEFTY genes.	LEFTY2 LEFTY1	1.18e-04	3	219	2	10886363
Pubmed	DNA sensor cGAS-mediated immune recognition.	IRF3 STING1	1.18e-04	3	219	2	27696330
Pubmed	Association of maternal hypertension and diabetes with variants of the NKX2-5, LEFTY1 and LEFTY2 genes in children with congenital heart defects: a case-control study from Pakistani Population.	LEFTY2 LEFTY1	1.18e-04	3	219	2	37097539
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-11	1.18e-04	3	219	2	9971820
Pubmed	SLC27A5 deficiency activates NRF2/TXNRD1 pathway by increased lipid peroxidation in HCC.	TXNRD1 SLC27A5	1.18e-04	3	219	2	31367013
Pubmed	Differential patterns of inhibition of the sugar transporters GLUT2, GLUT5 and GLUT7 by flavonoids.	SLC2A7 SLC2A5	1.18e-04	3	219	2	29548810
Pubmed	Differential regulation of mouse kidney sodium-dependent transporters mRNA by cadmium.	SLC5A2 SLC5A4	1.18e-04	3	219	2	11749115
Pubmed	A Baseline Cellular Antiviral State Is Maintained by cGAS and Its Most Frequent Naturally Occurring Variant rs610913.	IRF3 STING1	1.18e-04	3	219	2	35851540
Pubmed	Molecular and spatial mechanisms governing STING signalling.	IRF3 STING1	1.18e-04	3	219	2	33237620
Pubmed	Role of mouse peptidoglycan recognition protein PGLYRP2 in the innate immune response to Salmonella enterica serovar Typhimurium infection in vivo.	PGLYRP2 NOD1	1.18e-04	3	219	2	22615249
Pubmed	Activation of the cGAS-STING-IRF3 Axis by Type I and II Interferons Contributes to Host Defense.	IRF3 STING1	1.18e-04	3	219	2	39004913
Pubmed	Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition system.	LEFTY2 LEFTY1	1.18e-04	3	219	2	17011489
Pubmed	Runt-Related Transcription Factor 1 (RUNX1) Promotes TGF-β-Induced Renal Tubular Epithelial-to-Mesenchymal Transition (EMT) and Renal Fibrosis through the PI3K Subunit p110δ.	PIK3CD TGFB1	1.18e-04	3	219	2	29759484
Pubmed	STING-IRF3 Triggers Endothelial Inflammation in Response to Free Fatty Acid-Induced Mitochondrial Damage in Diet-Induced Obesity.	IRF3 STING1	1.18e-04	3	219	2	28302626
Pubmed	USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-Dependent Protein Levels.	SHANK1 USP8	1.18e-04	3	219	2	29735556
Pubmed	Diminished Innate Antiviral Response to Adenovirus Vectors in cGAS/STING-Deficient Mice Minimally Impacts Adaptive Immunity.	IRF3 STING1	1.18e-04	3	219	2	27076643
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-18	1.18e-04	3	219	2	10516026
Pubmed	Novel Helicobacter species H.japonicum isolated from laboratory mice from Japan induces typhlocolitis and lower bowel carcinoma in C57BL/129 IL10-/- mice.	LEFTY2 LEFTY1	1.18e-04	3	219	2	27655833
Pubmed	The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation.	IRF3 STING1	1.18e-04	3	219	2	18818105
Pubmed	Embryonic asymmetry: the left side gets all the best genes.	LEFTY2 LEFTY1	1.18e-04	3	219	2	9889116
Pubmed	GADD34 Promotes Tumor Growth by Inducing Myeloid-derived Suppressor Cells.	PPP1R15A TGFB1	1.18e-04	3	219	2	27630304
Pubmed	STING Is Involved in Antiviral Immune Response against VZV Infection via the Induction of Type I and III IFN Pathways.	IRF3 STING1	1.18e-04	3	219	2	28647346
Pubmed	Two modes by which Lefty proteins inhibit nodal signaling.	LEFTY2 LEFTY1	1.18e-04	3	219	2	15062104
Pubmed	FLRT3 and TGF-β/SMAD4 signalling: Impacts on apoptosis, autophagy and ion channels in supraventricular tachycardia.	FLRT3 TGFB1	1.18e-04	3	219	2	38509727
Pubmed	Requirements of LEFTY and Nodal overexpression for tumor cell survival under hypoxia in glioblastoma.	LEFTY2 LEFTY1	1.18e-04	3	219	2	33111989
Pubmed	Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system.	IRF3 STING1	1.18e-04	3	219	2	22728658
Pubmed	Dual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathway.	ULK3 SUFU	1.18e-04	3	219	2	20643644
Pubmed	TGFβ signaling in establishing left-right asymmetry.	LEFTY2 LEFTY1	1.18e-04	3	219	2	24704359
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	MAG LILRB2 IRF3 PPP1R15A LMTK3 FCGRT NFKBIB KCNJ14 SPACA6 MAMSTR SLC27A5 WDR62 SHANK1 LILRA2 PLEKHA4 FUZ RABAC1 TGFB1 SPTBN4 KASH5 MEGF8 RINL SBK3	1.74e-08	1192	219	23	chr19q13
Cytoband	1p36.2	SLC2A7 PIK3CD SLC2A5	2.96e-05	13	219	3	1p36.2
Cytoband	19q13.33	LMTK3 MAMSTR PLEKHA4 FUZ KASH5	1.62e-04	106	219	5	19q13.33
GeneFamily	Cyclin dependent kinases	CDK16 CDK17 CDKL1 CDK6	3.91e-05	26	135	4	496
GeneFamily	Fibronectin type III domain containing	EPHA6 IGSF9 FLRT3 IL27RA KALRN EPHA10	1.28e-03	160	135	6	555
GeneFamily	WD repeat domain containing\|Caspase recruitment domain containing\|Apoptosome	CARD10 NOD1 CARD6	1.43e-03	30	135	3	959
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	1.50e-03	8	135	2	939
GeneFamily	Phosphatidylinositol 3-kinase subunits	PIK3C2G PIK3CD	1.50e-03	8	135	2	831
GeneFamily	Plexins	PLXNB1 PLXNB3	1.93e-03	9	135	2	683
GeneFamily	Short chain dehydrogenase/reductase superfamily	HSD11B1L SDR39U1 RDH5 HSD3B7	2.52e-03	76	135	4	743
GeneFamily	Maestro heat like repeat containing	MROH7 MROH6	2.91e-03	11	135	2	636
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MUC21 MAP3K9 IGSF9 FLRT3 VWA2 RIPK4 SIX3 PLEKHG4B SYTL1	4.79e-07	197	213	9	58d809ccb8cc4b1e76acf0b8f996cd0e2637290c
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	MUC21 MAP3K9 IGSF9 FLRT3 VWA2 RIPK4 SIX3 PLEKHG4B SYTL1	4.79e-07	197	213	9	751f19b00f92e1334f653b870d3f7c0c149ff41a
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Basal_1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	MUC21 MAP3K9 IGSF9 FLRT3 VWA2 RIPK4 SIX3 PLEKHG4B SYTL1	4.79e-07	197	213	9	2701864e49878c5f323f5133e2c4b0a5a7fff7f5
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKL1 KCNC4 PIK3C2G MAP3K9 IGSF9 WDR62 PCDHA10 EPHA10	2.27e-06	177	213	8	9b02fd91c110b405eba6cb74ceb90b1286535973
ToppCell	facs-Heart-RA-18m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGLYRP2 LMTK3 ZNF831 PIK3CD NUP210 SIX3 CD6 RINL	2.27e-06	177	213	8	31201a72b7c1bdb0eff892b7072a35c80fd34727
ToppCell	facs-Heart-RA-18m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGLYRP2 LMTK3 ZNF831 PIK3CD NUP210 SIX3 CD6 RINL	2.27e-06	177	213	8	89d0131320cd96af8b0ee54f0f4d4771d17ef44e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF831 NCDN GRIN2A KIFC2 SPTBN4 LEFTY2 CELSR2 EPHA10	3.41e-06	187	213	8	e04a84989d624378141042768383b9c846901f2d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF831 NCDN GRIN2A KIFC2 SPTBN4 LEFTY2 CELSR2 EPHA10	3.41e-06	187	213	8	24cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF831 NCDN GRIN2A KIFC2 SPTBN4 LEFTY2 CELSR2 EPHA10	3.41e-06	187	213	8	2f153b203fe79f206319603cf94d3a03ab49a05d
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST HERC2 MYO18B SLC2A5 USP8 MACF1 SCAF11 UBASH3B	4.65e-06	195	213	8	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	Striatum-Neuronal-Excitatory\|Striatum / BrainAtlas - Mouse McCarroll V32	CDK17 ZNF831 ADCY5 NCDN KALRN GRIN2A SPTBN4 ANO3	4.83e-06	196	213	8	67400193ba469cf4d939e94f5ed94995e384bc07
ToppCell	5'-GW_trimst-2-LymphNode\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R15A ZNF831 SIRPG PASK NUP210 IL27RA CD6 SYTL1	5.40e-06	199	213	8	4a9ca133125dc25a06e7b1cfea15ecffa449c20e
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R15A ZNF831 SIRPG PASK NUP210 IL27RA CD6 SYTL1	5.40e-06	199	213	8	45d0d275ffb4183e3e71f4701e121ef9853ebd10
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R15A ZNF831 SIRPG PASK NUP210 IL27RA CD6 SYTL1	5.40e-06	199	213	8	da20998253ad08a4a127a98b991b26237edb61a2
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R15A ZNF831 SIRPG PASK NUP210 IL27RA CD6 SYTL1	5.40e-06	199	213	8	b01328a80db5bb088c44564cea0f6729b1a9805b
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CUL9 SIRPG IGSF9 PM20D1 ADAM12 MMEL1 GYS2	8.74e-06	152	213	7	eb7ff36792c3c54ac88cfe976f84016b70b1a1d7
ToppCell	cellseq2-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-Treg\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CUL9 ZNF831 VWDE PASK WDR62 SLC5A2 CD6	1.17e-05	159	213	7	048b6a97568242c8846034277680632e5de75840
ToppCell	facs-Marrow-T-cells-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGLYRP2 SHANK1 ALKBH7 HDHD5 SLC2A5 ULK3 UBE3D	1.22e-05	160	213	7	b3f7ef7e682b48a83ca425f5c439336e96168300
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCN12 ZNF831 PIK3CD IL27RA SAP25 CD6 SYTL1	1.32e-05	162	213	7	58fe827198c172eeaa26273b0fad7991a718b0bf
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM178B SIRPG PASK PIK3CD SHANK1 C11orf21 SYTL1	1.61e-05	167	213	7	484de3ca4a905067c18d06995601479eef8fc15e
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGRT DPEP2 NBEAL2 MYO18B KALRN ACAD10 RAB44	1.67e-05	168	213	7	e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MAMSTR MROH7 IGSF9 COX7B2 IL17RE TMEM82	1.74e-05	113	213	6	fed408864201218295bac0cc6647953fda8d688e
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MAMSTR MROH7 IGSF9 COX7B2 IL17RE TMEM82	1.74e-05	113	213	6	c0b8d7a2e3722029e850051bdff77f31f34a8cca
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MAMSTR MROH7 IGSF9 COX7B2 IL17RE TMEM82	1.74e-05	113	213	6	7e24c0f6a80e10a2a41325d48a87628bd330a1e2
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPACA6 IL27RA RCCD1 ACAD10 CD6 SLC17A1 RINL	1.95e-05	172	213	7	10a1d1838492b8ce6dea08844353b51571432c56
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-Regulatory_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPACA6 IL27RA RCCD1 ACAD10 CD6 SLC17A1 RINL	1.95e-05	172	213	7	d824e46c8040b0bb9235f9b8a2b35386b303caa0
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDR39U1 DPEP2 NBEAL2 NUP210 FLRT3 CMAHP SAP25	2.34e-05	177	213	7	f6b9d91d46830d0d207b0abd4ee5a4942fd99774
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CUL9 SAP25 SLC5A9 HSD3B7 CDH24 LTF MUC3A	2.61e-05	180	213	7	8d9be9cfdf98e5888654a28ab12e5e89f201af00
ToppCell	facs-Heart-RA-18m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGLYRP2 ZNF831 PIK3CD NUP210 SIX3 CD6 RINL	2.61e-05	180	213	7	9be0af61d496a29d737bb772ad09864797994299
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDR39U1 LRRC41 SLC5A9 RAB44 SUFU CDK6 TEDC1	2.70e-05	181	213	7	e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDR39U1 LRRC41 SLC5A9 RAB44 SUFU CDK6 TEDC1	2.70e-05	181	213	7	d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAM178B ITGA1 IRAG1 ADCY5 DST PCDHA10 LGR6	2.70e-05	181	213	7	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAG VWDE KCNC4 PM20D1 ADAM12 RAB44 TGFB1	2.80e-05	182	213	7	4cd5eb13f78f4f377932c50ac2acb4ac0cd14c12
ToppCell	Mild-CD4+_T\|Mild / Disease group and Cell class	STING1 PPP1R15A SH3YL1 PASK ADAM12 CD6 IL17RE	3.11e-05	185	213	7	c28ecb63146de1b02418e5a4fad0ae7c2b66a41d
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA1 PPP1R15A NIPBL ROCK2 USP8 MACF1 SCAF11	3.11e-05	185	213	7	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	VWDE PIK3C2G NUP210 MAP3K9 VWA2 RIPK4 PLEKHG4B	3.68e-05	190	213	7	625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ITGA1 IRAG1 RHCG TACC2 LEFTY2 LGR6 UBASH3B	4.20e-05	194	213	7	67f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCell	wk_08-11-Hematologic-Myeloid-Myelocyte-like\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	LILRB2 LILRA2 RCCD1 SLC2A5 TGFB1 LTF SYTL1	4.49e-05	196	213	7	4b88c96b737a747422674ad99c073b28e6febc7c
ToppCell	mLN-T_cell-Th1\|T_cell / Region, Cell class and subclass	GPR135 ITGA1 PPP1R15A ZSWIM4 SIX3 SLC17A1 ARMC5	4.63e-05	197	213	7	5e39a49dddef04469ff2b615d755ddf6a926e58e
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	DST NYNRIN IGSF9 PLXNB1 CELSR2 LGR6 SYTL1	4.63e-05	197	213	7	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_3-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MUC21 SIAE IGSF9 FLRT3 ULK3 ADGRD2 RNF39	4.63e-05	197	213	7	0f37afad46b94c748a149d9ee681472d7a3e6937
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_3\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	MUC21 SIAE IGSF9 FLRT3 ULK3 ADGRD2 RNF39	4.63e-05	197	213	7	4f8f23b1ef2eae9d300bd2c1a5cb7ef0163858a1
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Basal_3\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	MUC21 SIAE IGSF9 FLRT3 ULK3 ADGRD2 RNF39	4.63e-05	197	213	7	2cff37f9d33951840a8f52ccbba6ca1a4bbe3ad9
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	GPR135 ADCY5 DST GRIN2A CELSR2 ADAMTS7 MFSD8	4.78e-05	198	213	7	cc2b5b632e73e44bb60050f0db10d8f0dbb859fa
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-SELL+_CD8_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SIRPG PASK NUP210 IL27RA CD6 C11orf21 SYTL1	4.78e-05	198	213	7	0dac00a64fe08ec6669af3ddd4b82413b673233d
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ITGA1 IRAG1 ADCY5 MROH7 MYO18B TACC2 LGR6	5.10e-05	200	213	7	9169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARD10 FCGRT DPEP2 MYO18B AMBRA1 LTF	9.16e-05	152	213	6	82a493ffb2f1704cd6f68a82d970fe12f537d20e
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CUL9 SIRPG IGSF9 PM20D1 ADAM12 GYS2	9.16e-05	152	213	6	6d02b50e9e9ecf820f84a79e46d153a4840a1cfe
Drug	3-O-methyl-D-glucose	SLC2A7 STING1 SIAE PIK3C2G PIK3CD SLC2A5 SLC5A2 CS GYS2	2.47e-08	72	214	9	CID000008973
Drug	nocodazole; Down 200; 1uM; MCF7; HG-U133A	NOL6 LMF2 NFKBIB NUP210 NIPBL DPH2 HECTD3 TAF1C FUZ TACC2 NUP188 MVK	4.07e-07	198	214	12	621_DN
Drug	Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; HL60; HT_HG-U133A	LILRB2 FJX1 LRRC41 IL27RA LILRA2 TAF1C CD6 CELSR2 MEGF8 CDK6 ZNF44	2.40e-06	194	214	11	1267_UP
Disease	aspartate aminotransferase measurement	TNFRSF6B CDKL1 STN1 OR2B11 FCGRT CMAHP VARS1 MOV10 ARHGEF19 KALRN TGFB1 USP8 MROH6 CEP112 UBASH3B MVK CDK6	2.62e-04	904	209	17	EFO_0004736
Disease	Cushing syndrome	USP8 ARMC5	2.97e-04	4	209	2	cv:C0010481
Disease	Metastatic melanoma	PASK MAP3K9 ROCK2 CDK6	5.86e-04	54	209	4	C0278883
Disease	age of onset of anorexia nervosa	CDK17 CMAHP	1.02e-03	7	209	2	OBA_2050099
Disease	cholangiocarcinoma (is_marker_for)	PRSS56 TGFB1 RNF39 MUC3A	1.11e-03	64	209	4	DOID:4947 (is_marker_for)
Disease	low density lipoprotein cholesterol measurement, physical activity	NYNRIN MAMSTR C2CD2 CELSR2	1.25e-03	66	209	4	EFO_0003940, EFO_0004611
Disease	Malignant neoplasm of breast	XIRP1 LMF2 POP1 MROH7 HERC2 NIPBL PLXNB1 PNLIPRP1 KALRN RCCD1 TACC2 ADAM12 SLC2A5 TMEM25 MACF1 LGR6 DOP1A	1.75e-03	1074	209	17	C0006142
Disease	Autoinflammatory disorder	STING1 RNASEH2C MVK	1.94e-03	35	209	3	C3860213
Disease	Asthma, Occupational	HERC2 TGFB1	2.16e-03	10	209	2	C0264423
Disease	rhinitis (is_marker_for)	NOD1 CRHR2 TGFB1	4.25e-03	46	209	3	DOID:4483 (is_marker_for)
Disease	platelet-to-lymphocyte ratio	MUC21 ZNF831 ZSWIM4 CMAHP VARS1 KALRN ACAD10 CDK6	4.53e-03	363	209	8	EFO_0008446
Disease	Autosomal recessive primary microcephaly	WDR62 CDK6	4.93e-03	15	209	2	cv:C3711387
Disease	Myopia	PRSS56 RDH5	4.93e-03	15	209	2	C0027092
Disease	phospholipids in medium LDL measurement	ITGA1 NYNRIN CELSR2	5.08e-03	49	209	3	EFO_0022183
Disease	tumor necrosis factor-alpha measurement	LILRA2 OR52M1 ANO3	5.08e-03	49	209	3	EFO_0004684
Disease	developmental disorder of mental health (implicated_via_orthology)	PLXNB1 PLXNB3 GRIN2A	5.08e-03	49	209	3	DOID:0060037 (implicated_via_orthology)
Disease	response to tenofovir	GRIN2A SLC2A5 SLC17A1	5.68e-03	51	209	3	EFO_0009279
Disease	serum gamma-glutamyl transferase measurement	C16orf90 TNFRSF6B ITGA1 SH3YL1 NBEAL2 NFKBIB FSCN2 ARHGEF19 KALRN TGFB1 CELSR2 GYS2 UBASH3B CDK6	5.83e-03	914	209	14	EFO_0004532
Disease	total lipids in medium LDL	ITGA1 NYNRIN CELSR2	6.00e-03	52	209	3	EFO_0022180
Disease	total lipids in LDL measurement	ITGA1 NYNRIN CELSR2	6.00e-03	52	209	3	EFO_0022308

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSDSVWPLGKPEGLL	CARD10	571	Q9BWT7
RTSGGVLWDLESPPV	ARHGEF10L	951	Q9HCE6
PGPVRTLLSLEDAVW	ARHGEF10L	971	Q9HCE6
PIWGSLGLEETPSVG	CCDC187	986	A0A096LP49
LGPWLEELKTGPVRV	HSD3B7	46	Q9H2F3
IAGFLRGPDWSIPIL	CFAP36	16	Q96G28
TGCRPIPIIKLEWGS	GRM4	571	Q14833
SLGGLPQWEVEELPV	GYS2	11	P54840
LSTIPWGLPRTIEEL	FLRT3	166	Q9NZU0
WRLLTQDEGPALVPG	IBA57	196	Q5T440
PEGLPAWVLGELETS	CEP112	116	Q8N8E3
DPDLSRLLLGWAPGQ	DPH2	231	Q9BQC3
GVLIPSPGRVAAEWE	ACAD10	51	Q6JQN1
TPGQWETGLRLAPLR	ADAM12	876	O43184
EEPWGREGPALLLLS	ARMC5	516	Q96C12
WGSLLTSPAVRLPGI	DOP1A	186	Q5JWR5
ILDVIGLPGEEDWPR	CDK6	231	Q00534
WDSLLGPGAERLPLH	CELSR2	2761	Q9HCU4
ELERLALWPGLAASP	DNHD1	3951	Q96M86
GLLLPQPRSASEGIW	ADCY5	316	O95622
INSARWLPEPGLGLA	AMBRA1	1011	Q9C0C7
VPGARTLTETPLRGW	HSD11B1L	251	Q7Z5J1
GPEAAALRPGWLALL	DIPK2B	6	Q9H7Y0
PDAVLGRTIWGVLGL	BPNT1	161	O95861
VLRLWSEEGPRTPLG	CCDC154	576	A6NI56
ILWRVDPVGPLSFSG	DMXL1	706	Q9Y485
LWLSGLSEPGAARQP	CIAO2A	16	Q9H5X1
ALEGGLGPVDSELWP	ADAMTS7	1271	Q9UKP4
VEELWALLSPLPGGA	ABCA7	1436	Q8IZY2
PLPARATDIGIWLGI	ANO3	801	Q9BYT9
PPALLDISWLTESLG	POLM	96	Q9NP87
TPAGLKSILEALGPW	MROH7	556	Q68CQ1
LRAGPGPEALLQVWA	RCCD1	86	A6NED2
PEELRLTGWEPGALL	REC8	256	O95072
EPGSTPEGRLLWGLS	RAB44	471	Q7Z6P3
LPLVLGSAPGWDERT	PIK3C2G	691	O75747
EPLLGDTPGSREWDI	MFSD8	11	Q8NHS3
RRVGWTELLPPSLGL	KASH5	361	Q8N6L0
WSLPSDLLELLVPGV	LILRA2	206	Q8N149
DARTPWAEGGPLVLE	MRNIP	306	Q6NTE8
WEVPPFSGLERDGII	PM20D1	136	Q6GTS8
EELRAPGSRWSLGTP	ARHGEF19	56	Q8IW93
LLWPLSPGGSDTEIT	ARHGEF19	76	Q8IW93
LWEPGERLPVRLTNG	CD6	36	P30203
WLSTRPEVASIEPLG	NUP210	56	Q8TEM1
LELRPGSGVVAWDIP	HCFC1	176	P51610
GLHRRPLWETVPEGL	OTOP3	471	Q7RTS5
LSFGTPTLDEPWLGV	PASK	636	Q96RG2
LTGPSLVEVLRARPW	PASK	961	Q96RG2
SIAPGLLAVLWLGPR	OR52W1	81	Q6IF63
WVLPLASPGAALTGE	LEFTY1	11	O75610
SLGPGLRILSNEPWE	MAGED4	61	Q96JG8
PELRPELSWLGHEGL	MAG	166	P20916
TPGPTWPGDALRLLL	NCDN	451	Q9UBB6
PLTILGGPLLIRAAW	GHITM	206	Q9H3K2
AGWPVLLALTGVPAL	SLC2A7	196	Q6PXP3
PGGSLVPWEIFLITL	MUC21	471	Q5SSG8
ISLLGRSWLLPPGTL	LCN12	146	Q6JVE5
LGGIPAEALWELPSL	LGR6	126	Q9HBX8
PGSIRLALLLTWAGP	GPBAR1	121	Q8TDU6
WQRLIPEGIDIGEPL	HERC2	1696	O95714
WLLPVRPQEGGRITL	DST	1736	Q03001
PLAWKGRLPSDDVIG	KATNIP	781	O60303
LLLWSGADLRPVSGP	IL17RE	556	Q8NFR9
PLRWAAPELLGELHG	LMTK3	306	Q96Q04
PLDDWGPLFRTLAEL	CDH24	796	Q86UP0
LGAELGPGLSWAPLV	NFKBIB	36	Q15653
VSRPPLLRGLSWDSG	IRAG1	376	Q9Y6F6
LLRGLSWDSGPEEPG	IRAG1	381	Q9Y6F6
SGLPAPWISLRGDDT	FCGRT	326	P55899
PWISLRGDDTGVLLP	FCGRT	331	P55899
RWLLESLGGPALEVV	PNMA6E	361	A0A0J9YXQ4
KPALDWLTREGGELP	PLXNB1	836	O43157
WLELPGELRGLPATL	PLXNB3	721	Q9ULL4
TEPWGGTAIRPLKIL	PNLIPRP1	31	P54315
RDLAGWPLGVPQLAS	MUC3A	51	Q02505
GLLLWSDPGTASLPL	PGLYRP2	11	Q96PD5
GGPWPAAELGLVLAL	PEX6	26	Q13608
WVDGGLTNALPILPV	PNPLA4	161	P41247
AAEGWVPGSILAPLT	KALRN	2371	O60229
PEWPAAELLLSLLGR	NIPBL	1576	Q6KC79
RLLWGLEGLPLTVSA	NOL6	671	Q9H6R4
LALAEELLLDGWGPP	CRHR2	16	Q13324
IGIEWNLSPVGRVTP	COX7B2	61	Q8TF08
SVWGFREELAPLVGP	IL27RA	406	Q6UWB1
LWVGEGLGLPVALPA	MEGF8	1051	Q7Z7M0
GVTRSGRLILWEAPP	NEK8	346	Q86SG6
LLGDINWIRPTLGIP	HERVK_113	271	P63132
RPWLLEIGFSPSLLT	NOD1	101	Q9Y239
VWSSPSDLLELLVPG	LILRB2	206	Q8N423
LPWTTLDEFPLTRLG	KCNG1	76	Q9UIX4
GLLAQVPSLAEGRPW	MROH6	156	A6NGR9
IFRLLGTPSQETWPG	CDK17	401	Q00537
LALLLGPWRPGTAEE	EPHA10	21	Q5JZY3
GPWRPGTAEEVILLD	EPHA10	26	Q5JZY3
ISKDGLPGRVPLWVI	ITGA1	1131	P56199
SQPLLDILEVVGGWP	MMEL1	186	Q495T6
LLGDINWIRPTLGIP	ERVK-7	271	P63135
LLGDINWIRPTLGIP	ERVK-6	271	Q9BXR3
LLWPESGEILPITDA	MACF1	1856	Q9UPN3
LPGELLWGHRFEPVL	KCNJ14	321	Q9UNX9
FILLGVSDRPWLELP	OR2B11	16	Q5JQS5
ELVVTARDGGSPPLW	PCDHA10	421	Q9Y5I2
EALTLGLWSGPLPRV	POP1	941	Q99575
LLGDINWIRPTLGIP	ERVK-18	271	Q9QC07
SLLALWGGLLPPRTE	FJX1	21	Q86VR8
RPVLLLHPLGGWTKD	PAPSS1	446	O43252
PGLWPGAGTIRLEQD	GMPPA	211	Q96IJ6
TALGFSLPWELLGAP	GPR135	236	Q8IZ08
SLPWELLGAPRELAA	GPR135	241	Q8IZ08
PVLENSWLFPTRIGG	CARD6	726	Q9BX69
PRPGSDALLSWILTL	C2CD2	56	Q9Y426
EPALTPDEWLGGINR	CORO2B	376	Q9UQ03
LSWISGDLLPPGGQE	CACNA1G	2221	O43497
LLSGVPLWPGKSDVD	CDKL1	196	Q00532
RILGTPTEETWPGIL	CDK16	376	Q00536
GEEPLPEGLFWLLVT	CS	111	O75390
GFEPLTPWILDLLGH	ILF2	236	Q12905
EEPPRWLEGDLGSLS	DNAAF8	141	Q8IYS4
PEGTAWALDLPQGTL	C16orf90	96	A8MZG2
WVLPLAGPGAALTEE	LEFTY2	11	O00292
DSLDWLEALSGGPPL	MAMSTR	371	Q6ZN01
LEGPGTFGRWPLLSL	DPEP2	6	Q9H4A9
EPGPQRSGEALWLIP	CUL9	1836	Q8IWT3
PGRITWDELAASGLP	SDR39U1	36	Q9NRG7
LGPWLEAAGVAESPL	CERCAM	16	Q5T4B2
LELSWFPDTLPGIGR	SCAF11	231	Q99590
TLPLRPAVDSWGLGV	SBK3	216	P0C264
PPLAVLDFLGDDWGL	SBK3	296	P0C264
ELIEPWRPSLGELLA	SPACA6	271	W5XKT8
SIDLPGIKGLWPLRS	DDB1	401	Q16531
LPAPELWTELTGLAA	KIFC2	46	Q96AC6
GVLLWELLTGEVPFR	MAP3K9	336	P80192
RLGTPEAVLLPWLVG	FUZ	196	Q9BT04
RIGELGAPEVWGLSP	NKAP	136	Q8N5F7
LRGLGPLEPWLVEAV	PPP1R15A	36	O75807
DLALVQLWTPVSPGG	PRSS56	191	P0CW18
ELVGRLRWGPAPLLT	NYNRIN	136	Q9P2P1
APLLTPRGIWEAEVT	NYNRIN	146	Q9P2P1
LTEWPDTIPLSLALG	PTGR1	106	Q14914
ALILEWSPPSDTGGR	EPHA6	346	Q9UF33
SEVGDRTLPGWPVTL	IRF3	231	Q14653
PSSFWLTGIPGLESL	OR52M1	11	Q8NGK5
WVLEPDPGQGTAVLL	FSCN2	46	O14926
VLEPGLWSLVPGVDT	MIEF2	201	Q96C03
RGPSTAWLSGPELIA	SAP25	131	Q8TEE9
EWVDGLLPLRTNLAP	SYTL1	546	Q8IYJ3
VLGALGRALSPLEEW	VARS1	131	P26640
VTLWGLGEPPEHTLR	STING1	31	Q86WV6
ETPSLLWGLDPVFLA	STN1	11	Q9H668
TAGWNVPIGTLRPFL	LTF	141	P02788
PTLLWEAPRLGLDTA	LMF2	61	Q9BU23
LESGVWALPGPILQS	LRRC41	61	Q15345
PATVLWELLGPGESG	MOV10	211	Q9HCE1
LPQDEGAWPLRVTLL	PLEKHA4	761	Q9H4M7
PLIDPWDPGLTARDL	TAF1C	71	Q15572
PPETSLGAFGLLWDL	FAM178B	336	Q8IXR5
GWPILLGLTGVPAAL	SLC2A5	191	P22732
GPAIIGALLRKVPSW	NBEAL2	976	Q6ZNJ1
GVLLLGEPVRWETSL	HDHD5	191	Q9BXW7
LSLLIPPAAGIGVAW	SLC17A1	121	Q14916
RLPDGKWSAPSAIGI	SH3YL1	71	Q96HL8
ERLGRFLWSLPVAPG	SIX3	106	O95343
VLPLILWADRSAGIG	SIAE	11	Q9HAT2
LASSWPLGVSGPLIE	SHQ1	526	Q6PI26
FRDAVTGDIPWPGII	SLC5A4	266	Q9NY91
GDIPWPGLIFGLTVL	SLC5A9	276	Q2M3M2
PDSLEGWVPVREGLF	WHAMM	6	Q8TF30
TSLLPVGPVLWFRGV	SIRPG	56	Q9P1W8
GIIGPTPWLTRDDFQ	RDH5	116	Q92781
AALLPVTGRWRSPGE	RIPK4	291	P57078
SSLPRKLLPWEEGPG	SHANK1	1831	Q9Y566
PSEGLLFRWDPGALD	ADGRD2	296	Q7Z7M1
LFRWDPGALDVTPSL	ADGRD2	301	Q7Z7M1
ALGAGDPELLLTGPW	ADGRD2	441	Q7Z7M1
LLALRTLPGPSWVRG	ALKBH7	6	Q9BT30
ITWTPRPGATLDLGR	CMAHP	291	Q9Y471
LTPEGEAGLSWPVGL	CHPF2	346	Q9P2E5
PGQLPLAIRLGWDLD	C11orf21	96	Q9P2W6
LLGDINWIRPTLGIP	ERVK-25	271	P63136
LARLAAGPWLPGTLT	nan	31	P0C880
LVSAPRSLVWGPGLQ	POGLUT3	26	Q7Z4H8
LWPLGSFLVTGRDPS	RINL	66	Q6ZS11
LPALTEELIWSPDIG	RINL	456	Q6ZS11
LDFVTPTPLGTRWGL	TXNRD1	191	Q16881
IWLSLRDSETLPSPG	VWDE	91	Q8N2E2
GLGPWLAVEIPDLIQ	UFC1	141	Q9Y3C8
TGDLPWPALLLGLTI	SLC5A2	271	P31639
PVAVALTLRWLLGDP	SLC27A5	26	Q9Y2P5
IVVWSELPPGAGLGS	MVK	131	Q03426
ALWDPLSLLRGLPGA	PLEKHG4B	676	Q96PX9
LWLLVLTPGRPAAGL	TGFB1	16	P01137
RVLPLPSENWGALVG	UBE3D	126	Q7Z6J8
LLALSWLLARGPVPE	TEDC1	111	Q86SX3
LLGDINWIRPTLGIP	ERVK-10	271	P10266
ELLRTVPIAGGPWLI	SUFU	221	Q9UMX1
LVWSLDGIPFRGGPT	VWA2	406	Q5GFL6
LWGLETIPGPDAKVR	RNASEH2C	131	Q8TDP1
LPELFWGTEPTSGLG	NUP188	416	Q5SRE5
LEPSAQTWGPGTLRL	PIK3CD	171	O00329
LLGDINWIRPTLGIP	ERVK-11	271	Q9UQG0
DGFPESRLEGWLSLP	ROCK2	1146	O75116
PGLALDEWLPHLELG	SPTBN4	1166	Q9H254
DPASDKLLGPAGLTW	TACC2	1491	O95359
LPGLPSLEWGSSLLD	TMEM82	11	A0PJX8
VPSLRQSLLWGDPAG	IGSF9	811	Q9P2J2
QGSTLGLEDWPTLPI	MYO18B	2266	Q8IUG5
LLPKLIPSGAGREWL	RABAC1	21	Q9UI14
IVGLILRLPFWGQPS	RHCG	411	Q9UBD6
ALGLLQGSPARWSEP	WDR62	1381	O43379
TPAAVRAVPELGLWL	TMEM87B	36	Q96K49
VILGLIPSSEEGWPI	TRMT12	306	Q53H54
PGWRSIEEVLRILPG	VPS33A	506	Q96AX1
LGETGIWQLTDPPIL	UBASH3B	616	Q8TF42
SPLVSPNGRLELGWQ	ZNF831	746	Q5JPB2
SGVVSRLEQGEPWIP	ZSCAN29	181	Q8IWY8
RLEQGEPWIPDLLGS	ZSCAN29	186	Q8IWY8
GGSLEVRSLRPAWPT	PRO2829	31	Q9P1C3
GEDLRSPSPGWKIIS	ZNF79	101	Q15937
RIVPGLPSGWAKFLD	USP8	646	P40818
ALPRGLPGGWVTIQD	XIRP1	1126	Q702N8
TRDLKWGTPVPLEGF	MARS1	496	P56192
GLTEGIWQLVPPSLF	UIMC1	151	Q96RL1
VTLPRGQPEVLEWGL	ZNF44	31	P15621
LLPALLSSGWGELEP	TMEM25	16	Q86YD3
WGPPRLDGFILTERL	ULK3	6	Q6PHR2
WRSGPEFTLLTRIPG	WDR54	196	Q9H977
GGRLWALTAPEPTLL	RNF39	341	Q9H2S5
RLLQALEAPEGWGPT	TNFRSF6B	231	O95407
VARLLSPDLWEQGPL	ZAN	101	Q9Y493
DILRRWTLSAPGLGP	ZSWIM4	881	Q9H7M6
AGPSRVLLPVWEAEG	HECTD3	56	Q5T447
TLPGTRLAWLADPDG	KCNC4	56	Q03721
WRALSGLLPPDTAIL	LRIG2	66	O94898
LRTLWGPEQAAGLPL	GRIN2A	51	Q12879