Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR4K17 OR4S2 OR2AP1 OR9I1 TAAR2 OR6C65 PTH2R OR10A3 OR51A7 GPR161 OR5AC2 OR6C70 RXFP2 OR5H6 CCR8 OR6C6 OR51H1	1.11e-06	884	97	17	GO:0004930
GeneOntologyMolecularFunction	olfactory receptor activity	OR4K17 OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR5AC2 OR6C70 OR5H6 OR6C6 OR51H1	1.19e-06	431	97	12	GO:0004984
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	IL31RA OR4K17 OR4S2 OR2AP1 OR9I1 TAAR2 OR6C65 PLXND1 PTH2R OR10A3 OR51A7 GPR161 OR5AC2 OR6C70 RXFP2 OR5H6 CCR8 OR6C6 PLXNA1 PLXNA2 OR51H1	1.67e-06	1353	97	21	GO:0004888
GeneOntologyMolecularFunction	polyspecific organic cation:proton antiporter activity	SLC47A2 SLC47A1	2.34e-05	2	97	2	GO:0140968
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXND1 PLXNA1 PLXNA2	2.37e-05	12	97	3	GO:0017154
GeneOntologyMolecularFunction	GTPase activator activity	RALGAPA1 RAP1GAP2 CHML ARHGEF11 ANKRD27 TIAM2 ALDH1A1 SOS1	6.48e-05	279	97	8	GO:0005096
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RALGAPA1 RAP1GAP2 CHML ARHGEF11 ANKRD27 TIAM2 ARHGEF33 GNA13 ALDH1A1 SOS1	1.78e-04	507	97	10	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RALGAPA1 RAP1GAP2 CHML ARHGEF11 ANKRD27 TIAM2 ARHGEF33 GNA13 ALDH1A1 SOS1	1.78e-04	507	97	10	GO:0030695
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	ARHGEF11 ANKRD27 TIAM2 ARHGEF33 GNA13 SOS1	9.24e-04	231	97	6	GO:0005085
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR4K17 OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR5AC2 OR6C70 OR5H6 OR6C6 OR51H1	8.74e-07	432	97	12	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR4K17 OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR5AC2 OR6C70 OR5H6 OR6C6 OR51H1	1.88e-06	465	97	12	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR4K17 OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR5AC2 OR6C70 OR5H6 OR6C6 OR51H1	2.91e-06	485	97	12	GO:0050907
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR4K17 OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 ARRB2 OR5AC2 OR6C70 OR5H6 OR6C6 OR51H1	3.35e-06	582	97	13	GO:0050906
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR4K17 OR4S2 OR2AP1 OR9I1 TAAR2 OR6C65 ARHGEF11 PTH2R OR10A3 OR51A7 GPR161 ARRB2 OR5AC2 GNA13 OR6C70 RXFP2 OR5H6 CCR8 OR6C6 OR51H1	6.29e-06	1395	97	20	GO:0007186
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR4K17 OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR5AC2 OR6C70 OR5H6 OR6C6 OR51H1	6.40e-06	524	97	12	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR4K17 OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR5AC2 OR6C70 OR5H6 OR6C6 OR51H1	9.86e-06	547	97	12	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus	OR4K17 OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 ARRB2 OR5AC2 OR6C70 OR5H6 OR6C6 OR51H1	3.31e-05	722	97	13	GO:0051606
GeneOntologyBiologicalProcess	homologous chromosome pairing at meiosis	HORMAD1 FANCD2 SYCP2 TERB1	1.83e-04	60	97	4	GO:0007129
GeneOntologyBiologicalProcess	positive regulation of axonogenesis	PLXND1 TIAM2 ANAPC2 PLXNA1 PLXNA2	2.03e-04	114	97	5	GO:0050772
GeneOntologyBiologicalProcess	response to thyroxine	CRLS1 GCLC	2.17e-04	5	97	2	GO:0097068
GeneOntologyBiologicalProcess	dichotomous subdivision of terminal units involved in salivary gland branching	PLXND1 PLXNA1	2.17e-04	5	97	2	GO:0060666
GeneOntologyBiologicalProcess	response to L-phenylalanine derivative	CRLS1 GCLC	3.24e-04	6	97	2	GO:1904386
GeneOntologyCellularComponent	semaphorin receptor complex	PLXND1 PLXNA1 PLXNA2	2.68e-05	13	97	3	GO:0002116
Domain	GPCR_Rhodpsn_7TM	OR4K17 OR4S2 OR2AP1 OR9I1 TAAR2 OR6C65 OR10A3 OR51A7 GPR161 OR5AC2 OR6C70 RXFP2 OR5H6 CCR8 OR6C6	7.84e-07	670	91	15	IPR017452
Domain	7tm_1	OR4K17 OR4S2 OR2AP1 OR9I1 TAAR2 OR6C65 OR10A3 OR51A7 GPR161 OR5AC2 OR6C70 RXFP2 OR5H6 CCR8 OR6C6	8.93e-07	677	91	15	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR4K17 OR4S2 OR2AP1 OR9I1 TAAR2 OR6C65 OR10A3 OR51A7 GPR161 OR5AC2 OR6C70 RXFP2 OR5H6 CCR8 OR6C6	1.03e-06	685	91	15	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR4K17 OR4S2 OR2AP1 OR9I1 TAAR2 OR6C65 OR10A3 OR51A7 GPR161 OR5AC2 OR6C70 RXFP2 OR5H6 CCR8 OR6C6	1.15e-06	691	91	15	PS50262
Domain	GPCR_Rhodpsn	OR4K17 OR4S2 OR2AP1 OR9I1 TAAR2 OR6C65 OR10A3 OR51A7 GPR161 OR5AC2 OR6C70 RXFP2 OR5H6 CCR8 OR6C6	1.17e-06	692	91	15	IPR000276
Domain	Olfact_rcpt	OR4K17 OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR5AC2 OR6C70 OR5H6 OR6C6	3.26e-06	393	91	11	IPR000725
Domain	Plexin_cytopl	PLXND1 PLXNA1 PLXNA2	9.20e-06	9	91	3	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXND1 PLXNA1 PLXNA2	9.20e-06	9	91	3	IPR013548
Domain	Plexin	PLXND1 PLXNA1 PLXNA2	9.20e-06	9	91	3	IPR031148
Domain	MATE_fam	SLC47A2 SLC47A1	2.35e-05	2	91	2	IPR002528
Domain	MatE	SLC47A2 SLC47A1	2.35e-05	2	91	2	PF01554
Domain	HORMA_dom	HORMAD1 MAD2L1	1.40e-04	4	91	2	IPR003511
Domain	HORMA	HORMAD1 MAD2L1	1.40e-04	4	91	2	PS50815
Domain	HORMA	HORMAD1 MAD2L1	1.40e-04	4	91	2	PF02301
Domain	-	HORMAD1 MAD2L1	1.40e-04	4	91	2	3.30.900.10
Domain	ARM-type_fold	RALGAPA1 MROH2A USP24 FHOD3 LYST SDAD1 FHOD1 TERB1	2.49e-04	339	91	8	IPR016024
Domain	IPT	PLXND1 PLXNA1 PLXNA2	3.01e-04	27	91	3	SM00429
Domain	RhoGEF	ARHGEF11 TIAM2 ARHGEF33 SOS1	3.38e-04	68	91	4	SM00325
Domain	RhoGEF	ARHGEF11 TIAM2 ARHGEF33 SOS1	3.78e-04	70	91	4	PF00621
Domain	DH_2	ARHGEF11 TIAM2 ARHGEF33 SOS1	3.78e-04	70	91	4	PS50010
Domain	DH-domain	ARHGEF11 TIAM2 ARHGEF33 SOS1	3.99e-04	71	91	4	IPR000219
Domain	-	ARHGEF11 TIAM2 ARHGEF33 SOS1	3.99e-04	71	91	4	1.20.900.10
Domain	TIG	PLXND1 PLXNA1 PLXNA2	4.56e-04	31	91	3	PF01833
Domain	Sema	PLXND1 PLXNA1 PLXNA2	4.56e-04	31	91	3	SM00630
Domain	Semap_dom	PLXND1 PLXNA1 PLXNA2	4.56e-04	31	91	3	IPR001627
Domain	Sema	PLXND1 PLXNA1 PLXNA2	4.56e-04	31	91	3	PF01403
Domain	SEMA	PLXND1 PLXNA1 PLXNA2	4.56e-04	31	91	3	PS51004
Domain	Plectin_repeat	PPL PLEC	4.85e-04	7	91	2	IPR001101
Domain	Plectin	PPL PLEC	4.85e-04	7	91	2	PF00681
Domain	PLEC	PPL PLEC	4.85e-04	7	91	2	SM00250
Domain	PSI	PLXND1 PLXNA1 PLXNA2	5.01e-04	32	91	3	PF01437
Domain	IPT	PLXND1 PLXNA1 PLXNA2	5.01e-04	32	91	3	IPR002909
Domain	Plexin_repeat	PLXND1 PLXNA1 PLXNA2	5.01e-04	32	91	3	IPR002165
Domain	GDS_CDC24_CS	ARHGEF11 TIAM2 SOS1	9.01e-04	39	91	3	IPR001331
Domain	Rap_GAP	RALGAPA1 RAP1GAP2	1.03e-03	10	91	2	PF02145
Domain	GBD/FH3_dom	FHOD3 FHOD1	1.25e-03	11	91	2	IPR014768
Domain	Rap_GAP_dom	RALGAPA1 RAP1GAP2	1.25e-03	11	91	2	IPR000331
Domain	RAPGAP	RALGAPA1 RAP1GAP2	1.25e-03	11	91	2	PS50085
Domain	GBD_FH3	FHOD3 FHOD1	1.25e-03	11	91	2	PS51232
Domain	PSI	PLXND1 PLXNA1 PLXNA2	1.28e-03	44	91	3	IPR016201
Domain	PSI	PLXND1 PLXNA1 PLXNA2	1.46e-03	46	91	3	SM00423
Domain	Ig_E-set	PLXND1 ARRB2 PLXNA1 PLXNA2	1.67e-03	104	91	4	IPR014756
Domain	FH2	FHOD3 FHOD1	2.37e-03	15	91	2	PS51444
Domain	FH2_Formin	FHOD3 FHOD1	2.37e-03	15	91	2	IPR015425
Domain	FH2	FHOD3 FHOD1	2.37e-03	15	91	2	PF02181
Domain	FH2	FHOD3 FHOD1	2.37e-03	15	91	2	SM00498
Domain	DH_1	ARHGEF11 TIAM2 SOS1	3.60e-03	63	91	3	PS00741
Domain	UCH	USP24 USP7 PAN2	5.04e-03	71	91	3	PF00443
Domain	USP_3	USP24 USP7 PAN2	5.24e-03	72	91	3	PS50235
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR4K17 OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR5AC2 OR6C70 OR5H6 OR6C6 OR51H1	2.85e-06	417	78	12	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR4K17 OR4S2 OR9I1 OR6C65 OR10A3 OR51A7 ARRB2 OR5AC2 OR6C70 OR5H6 OR6C6	9.08e-06	389	78	11	M14091
Pathway	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	ARHGEF11 TIAM2 ARHGEF33 GNA13 SOS1	9.66e-06	52	78	5	MM14743
Pathway	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	ARHGEF11 TIAM2 ARHGEF33 GNA13 SOS1	1.81e-05	59	78	5	M11215
Pathway	REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE	ARHGEF11 TIAM2 ARHGEF33 GNA13 SOS1	4.16e-05	70	78	5	MM14824
Pathway	REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE	ARHGEF11 TIAM2 ARHGEF33 GNA13 SOS1	6.19e-05	76	78	5	M19832
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	ARHGEF11 TIAM2 ARHGEF33 GNA13 SOS1	6.59e-05	77	78	5	MM15044
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	ARHGEF11 TIAM2 ARHGEF33 GNA13 SOS1	7.92e-05	80	78	5	M800
Pathway	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	ARHGEF11 TIAM2 ARHGEF33 GNA13 SOS1	1.06e-04	85	78	5	MM14746
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	PLXND1 PLXNA1 PLXNA2	1.48e-04	19	78	3	M10959
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	PLXND1 ARHGEF11 PLXNA1 PLXNA2	1.78e-04	51	78	4	MM14967
Pathway	REACTOME_SENSORY_PERCEPTION	OR4K17 OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR5AC2 OR6C70 OR5H6 OR6C6 OR51H1	1.81e-04	636	78	12	M41834
Pathway	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	ARHGEF11 TIAM2 ARHGEF33 GNA13 SOS1	1.97e-04	97	78	5	M9400
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	PLXND1 ARHGEF11 PLXNA1 PLXNA2	4.28e-04	64	78	4	M7923
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR6C70 OR5H6 OR6C6 OR51H1	4.14e-08	340	97	10	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR6C70 OR5H6 OR6C6 OR51H1	4.14e-08	340	97	10	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR6C70 OR5H6 OR6C6 OR51H1	4.49e-08	343	97	10	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR4S2 OR2AP1 OR9I1 OR6C65 OR10A3 OR51A7 OR6C70 OR5H6 OR6C6 OR51H1	4.88e-08	346	97	10	14611657
Pubmed	Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.	PLXND1 PLXNA1 PLXNA2	4.54e-06	12	97	3	25839327
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXND1 PLXNA1 PLXNA2	4.54e-06	12	97	3	21270798
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXND1 PLXNA1 PLXNA2	5.89e-06	13	97	3	10520995
Pubmed	Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A.	PLXNA1 PLXNA2	7.70e-06	2	97	2	10781943
Pubmed	Evaluation of 4',6-diamidino-2-phenylindole as a fluorescent probe substrate for rapid assays of the functionality of human multidrug and toxin extrusion proteins.	SLC47A2 SLC47A1	7.70e-06	2	97	2	20047987
Pubmed	Lack of effect of the SLC47A1 and SLC47A2 gene polymorphisms on the glycemic response to metformin in type 2 diabetes mellitus patients.	SLC47A2 SLC47A1	7.70e-06	2	97	2	30433870
Pubmed	A human transporter protein that mediates the final excretion step for toxic organic cations.	SLC47A2 SLC47A1	7.70e-06	2	97	2	16330770
Pubmed	Functional characteristics of two human MATE transporters: kinetics of cimetidine transport and profiles of inhibition by various compounds.	SLC47A2 SLC47A1	7.70e-06	2	97	2	20067714
Pubmed	Rapid Regulation of Human Multidrug and Extrusion Transporters hMATE1 and hMATE2K.	SLC47A2 SLC47A1	7.70e-06	2	97	2	32708212
Pubmed	Fhos2, a novel formin-related actin-organizing protein, probably associates with the nestin intermediate filament.	FHOD3 FHOD1	7.70e-06	2	97	2	15966898
Pubmed	Identification and characterization of human FHOD3 gene in silico.	FHOD3 FHOD1	7.70e-06	2	97	2	15010865
Pubmed	Heterozygous variants of multidrug and toxin extrusions (MATE1 and MATE2-K) have little influence on the disposition of metformin in diabetic patients.	SLC47A2 SLC47A1	7.70e-06	2	97	2	20016398
Pubmed	The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations.	SLC47A2 SLC47A1	7.70e-06	2	97	2	16996621
Pubmed	The effect of novel promoter variants in MATE1 and MATE2 on the pharmacokinetics and pharmacodynamics of metformin.	SLC47A2 SLC47A1	7.70e-06	2	97	2	23267855
Pubmed	Impact of Experimental Conditions on the Evaluation of Interactions between Multidrug and Toxin Extrusion Proteins and Candidate Drugs.	SLC47A2 SLC47A1	7.70e-06	2	97	2	27271370
Pubmed	Identification of multidrug and toxin extrusion (MATE1 and MATE2-K) variants with complete loss of transport activity.	SLC47A2 SLC47A1	7.70e-06	2	97	2	19158817
Pubmed	Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters.	SLC47A2 SLC47A1	7.70e-06	2	97	2	17509534
Pubmed	Cytolinker cross-talk: periplakin N-terminus interacts with plectin to regulate keratin organisation and epithelial migration.	PPL PLEC	7.70e-06	2	97	2	17662978
Pubmed	Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.	PLXND1 PLXNA1 PLXNA2	1.15e-05	16	97	3	18489001
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	PLXND1 PLXNA1 PLXNA2	1.39e-05	17	97	3	11683995
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXND1 PLXNA1 PLXNA2	1.39e-05	17	97	3	17626059
Pubmed	PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development.	PLXND1 PLXNA1 PLXNA2	1.97e-05	19	97	3	15239958
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA1 PLXNA2	2.31e-05	3	97	2	27397516
Pubmed	Gαs directly drives PDZ-RhoGEF signaling to Cdc42.	ARHGEF11 GNA13	2.31e-05	3	97	2	33023908
Pubmed	Genetic variants and clinical relevance associated with gestational diabetes mellitus in Chinese women: a case-control study.	PLXND1 ARHGEF11	2.31e-05	3	97	2	28554271
Pubmed	Identification of plexin family molecules in mice.	PLXNA1 PLXNA2	2.31e-05	3	97	2	8806646
Pubmed	Plakins: a family of versatile cytolinker proteins.	PPL PLEC	2.31e-05	3	97	2	11854008
Pubmed	Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development.	PLXNA1 PLXNA2	2.31e-05	3	97	2	29091353
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA1 PLXNA2	2.31e-05	3	97	2	18625214
Pubmed	Plexins promote Hedgehog signaling through their cytoplasmic GAP activity.	PLXNA1 PLXNA2	2.31e-05	3	97	2	36169302
Pubmed	Differential expression of plexin-A subfamily members in the mouse nervous system.	PLXNA1 PLXNA2	2.31e-05	3	97	2	11241833
Pubmed	Fhod1, an actin-organizing formin family protein, is dispensable for cardiac development and function in mice.	FHOD3 FHOD1	2.31e-05	3	97	2	31008549
Pubmed	Genome-wide gene-environment interaction analysis for asbestos exposure in lung cancer susceptibility.	PTH2R PPL	2.31e-05	3	97	2	22637743
Pubmed	Inhibition of OCT2, MATE1 and MATE2-K as a possible mechanism of drug interaction between pazopanib and cisplatin.	SLC47A2 SLC47A1	2.31e-05	3	97	2	27178732
Pubmed	Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.	FANCD2 POLQ	2.31e-05	3	97	2	25642963
Pubmed	A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho.	ARHGEF11 GNA13	2.31e-05	3	97	2	10026210
Pubmed	The DNA sequence, annotation and analysis of human chromosome 3.	DNAH12 OR5AC2 TMPRSS7 PLXNA1	2.80e-05	62	97	4	16641997
Pubmed	Variants in the 1q21 risk region are associated with a visual endophenotype of autism and schizophrenia.	OR6C65 OR6C70 OR6C6	4.08e-05	24	97	3	24152035
Pubmed	TRIP13 localizes to synapsed chromosomes and functions as a dosage-sensitive regulator of meiosis.	HORMAD1 SYCP2	4.60e-05	4	97	2	39207914
Pubmed	Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulation.	ANAPC2 MAD2L1	4.60e-05	4	97	2	11438673
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA1 PLXNA2	4.60e-05	4	97	2	11306810
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA1 PLXNA2	4.60e-05	4	97	2	25518740
Pubmed	Prolonged RXFP1 and RXFP2 signaling can be explained by poor internalization and a lack of beta-arrestin recruitment.	ARRB2 RXFP2	4.60e-05	4	97	2	19279230
Pubmed	Determination of cell adhesion sites of neuropilin-1.	PLXNA1 PLXNA2	4.60e-05	4	97	2	10725340
Pubmed	The CSN3 subunit of the COP9 signalosome interacts with the HD region of Sos1 regulating stability of this GEF protein.	COPS3 SOS1	4.60e-05	4	97	2	30631038
Pubmed	A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.	PLXNA1 PLXNA2	4.60e-05	4	97	2	8570614
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CHD2 LYST PPL NUP205 GCLC FAM186A N4BP2 GNA13 ALDH1A1 PLEC TMPRSS7 POLQ POFUT2 PLXNA2	4.66e-05	1442	97	14	35575683
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	USP24 ARHGEF11 ARRB2 GCLC USP7 PLEC MOV10	5.22e-05	344	97	7	30333137
Pubmed	Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.	ARHGEF11 GNA13	7.66e-05	5	97	2	12515866
Pubmed	Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.	PLXNA1 PLXNA2	7.66e-05	5	97	2	25313870
Pubmed	Precise comparison of protein localization among OCT, OAT, and MATE in human kidney.	SLC47A2 SLC47A1	7.66e-05	5	97	2	23630107
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	MROH2A PRPF38B FHOD3 SDAD1 NUP205 DNAH12 PLEC POLQ	7.71e-05	496	97	8	31343991
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP24 USP7 PAN2 TMPRSS7	8.02e-05	81	97	4	12838346
Pubmed	Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA.	FANCD2 USP7	1.15e-04	6	97	2	32510829
Pubmed	A bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosis.	ARHGEF11 GNA13	1.15e-04	6	97	2	20300064
Pubmed	The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation.	ANAPC2 MAD2L1	1.15e-04	6	97	2	9637688
Pubmed	Potent activation of RhoA by Galpha q and Gq-coupled receptors.	ARHGEF11 GNA13	1.15e-04	6	97	2	12016230
Pubmed	Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation.	ANAPC2 MAD2L1	1.15e-04	6	97	2	17443186
Pubmed	Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages.	PLXNA1 PLXNA2	1.15e-04	6	97	2	19480842
Pubmed	The human olfactory receptor gene family.	OR4K17 OR4S2 OR2AP1 OR9I1 OR10A3 OR51A7 OR5H6 OR51H1	1.40e-04	541	97	8	14983052
Pubmed	Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.	PLXNA1 PLXNA2	1.60e-04	7	97	2	19063725
Pubmed	Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.	PLXNA1 PLXNA2	1.60e-04	7	97	2	19655386
Pubmed	Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.	PLXNA1 PLXNA2	1.60e-04	7	97	2	10520994
Pubmed	EZH2-CCF-cGAS Axis Promotes Breast Cancer Metastasis.	USP24 USP7	1.60e-04	7	97	2	35163710
Pubmed	Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.	ARHGEF11 TIAM2 SOS1	1.65e-04	38	97	3	11756498
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	IL31RA ITPRIPL2 PLXND1 SLC47A2 NUP205 FANCD2 TMEM168 GCLC GNA13 SLC35B4 PLXNA1	1.84e-04	1061	97	11	33845483
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNA1 PLXNA2	2.13e-04	8	97	2	15661641
Pubmed	Mouse HORMAD1 is a meiosis i checkpoint protein that modulates DNA double- strand break repair during female meiosis.	HORMAD1 SYCP2	2.13e-04	8	97	2	23759310
Pubmed	Polycomb protein SCML2 associates with USP7 and counteracts histone H2A ubiquitination in the XY chromatin during male meiosis.	SYCP2 USP7	2.13e-04	8	97	2	25634095
Pubmed	Integration of opposing semaphorin guidance cues in cortical axons.	PLXNA1 PLXNA2	2.13e-04	8	97	2	22368082
Pubmed	Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta.	ADAM12 MAD2L1	2.13e-04	8	97	2	10527948
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	IL31RA CHD2 LYST SDAD1 SLC35B4 ANAPC2 USP7 PLEC MAD2L1 SOS1	2.31e-04	910	97	10	36736316
Pubmed	NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.	ARHGEF11 TIAM2 SOS1	2.39e-04	43	97	3	12376548
Pubmed	PlexinA2 and semaphorin signaling during cardiac neural crest development.	PLXNA1 PLXNA2	2.74e-04	9	97	2	11688557
Pubmed	Plakin proteins are coordinately cleaved during apoptosis but preferentially through the action of different caspases.	PPL PLEC	2.74e-04	9	97	2	15500642
Pubmed	The role of neuropilins in cell signalling.	PLXNA1 PLXNA2	2.74e-04	9	97	2	19909241
Pubmed	TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.	PLXND1 PLXNA1 PLXNA2	3.12e-04	47	97	3	35462405
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	USP24 PRPF38B PATL1 PPL FANCD2 FHOD1 USP7 PLEC SOS1	3.19e-04	774	97	9	15302935
Pubmed	FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.	COPS3 GTPBP10 SDAD1 GNA13 PLEC	3.28e-04	212	97	5	33462405
Pubmed	Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.	PLXNA1 PLXNA2	3.41e-04	10	97	2	18804103
Pubmed	The anaphase promoting complex/cyclosome ubiquitylates histone H2B on the promoter during UbcH10 transactivation.	ANAPC2 MAD2L1	3.41e-04	10	97	2	36520528
Pubmed	Nek2A destruction marks APC/C activation at the prophase-to-prometaphase transition by spindle-checkpoint-restricted Cdc20.	ANAPC2 MAD2L1	3.41e-04	10	97	2	25673878
Pubmed	Class 3 semaphorins negatively regulate dermal lymphatic network formation.	PLXNA1 PLXNA2	4.17e-04	11	97	2	26319580
Pubmed	Evidence for new homotypic and heterotypic interactions between transmembrane helices of proteins involved in receptor tyrosine kinase and neuropilin signaling.	GYPA PLXNA1	4.17e-04	11	97	2	25315821
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	PLXND1 PLXNA1 PLXNA2	4.21e-04	52	97	3	26633812
Pubmed	A human MAP kinase interactome.	RAP1GAP2 ARHGEF11 ARRB2 N4BP2 FHOD1 PLEC SOS1	4.34e-04	486	97	7	20936779
Pubmed	Multidimensional Proteomics Reveals a Role of UHRF2 in the Regulation of Epithelial-Mesenchymal Transition (EMT).	CHD2 FANCD2 USP7	4.97e-04	55	97	3	27114453
Pubmed	New functions of Semaphorin 3E and its receptor PlexinD1 during developing and adult hippocampal formation.	PLXND1 PLXNA1	4.99e-04	12	97	2	29358640
Pubmed	PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.	PLXNA1 PLXNA2	4.99e-04	12	97	2	31690636
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	PLXNA1 PLXNA2	4.99e-04	12	97	2	24179230
Pubmed	Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.	ARHGEF11 GNA13	4.99e-04	12	97	2	12123608
Pubmed	Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.	PLXNA1 PLXNA2	4.99e-04	12	97	2	23991118
Pubmed	The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC.	ANAPC2 MAD2L1	4.99e-04	12	97	2	18722180
Pubmed	Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.	PLXNA1 PLXNA2	4.99e-04	12	97	2	28407732
Pubmed	USP51 promotes deubiquitination and stabilization of ZEB1.	USP7 PAN2	5.89e-04	13	97	2	29119051
Pubmed	Functional assembly of accessory optic system circuitry critical for compensatory eye movements.	PLXNA1 PLXNA2	5.89e-04	13	97	2	25959730
Cytoband	12q13.2	OR2AP1 OR6C65 OR6C70 PAN2 OR6C6	1.21e-07	55	97	5	12q13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	OR2AP1 OR6C65 FAM186A OR6C70 PAN2 OR6C6	2.88e-04	423	97	6	chr12q13
Cytoband	3q12.1	OR5AC2 OR5H6	9.04e-04	21	97	2	3q12.1
Cytoband	3q13.2	TMPRSS7 CD200R1L	1.97e-03	31	97	2	3q13.2
GeneFamily	Plexins	PLXND1 PLXNA1 PLXNA2	4.21e-06	9	68	3	683
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF11 TIAM2 ARHGEF33 SOS1	1.11e-04	66	68	4	722
GeneFamily	EF-hand domain containing\|Plakins	PPL PLEC	3.85e-04	8	68	2	939
GeneFamily	Olfactory receptors, family 6	OR6C65 OR6C70 OR6C6	9.31e-04	51	68	3	153
GeneFamily	Ubiquitin specific peptidases	USP24 USP7 PAN2	1.22e-03	56	68	3	366
ToppCell	mLN-(1)_T_cell-(10)_CD8_T\|mLN / shred on region, Cell_type, and subtype	CD244 LYST STAT4 ARRB2 ATP8A1 TPRG1	4.76e-06	200	96	6	6f02ba3a76e8aa3083efea9cb4ee587799c61fda
ToppCell	mLN-T_cell-CD8_T\|mLN / Region, Cell class and subclass	CD244 LYST STAT4 ARRB2 ATP8A1 TPRG1	4.76e-06	200	96	6	a221213f9245297a5d6196564c1043f8c17eb857
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHOD3 PTH2R ARHGEF33 SNTG2 PLXNA2	2.37e-05	158	96	5	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHOD3 PTH2R ARHGEF33 SNTG2 PLXNA2	2.37e-05	158	96	5	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD244 ITGAD ADAM12 STAT4 CD200R1L	2.75e-05	163	96	5	d18fee517e0daed51f89703f94f218567c83cb03
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-CD45____NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD244 ITGAD ADAM12 STAT4 CD200R1L	2.75e-05	163	96	5	f4a6e28ad3c1fcbf62ed9b2bf09f65d2ab0b31d1
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	SLC25A46 LRRC8C STAT4 PGAP1 POLQ	3.00e-05	166	96	5	c73fce59256ad501864f44f76cfae2fc33b3777e
ToppCell	LPS-antiTNF-Endothelial-Mes-Like-Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC25A46 HORMAD1 TIAM2 SNTG2 PLXNA1	3.00e-05	166	96	5	94a00edf66d54bc5f7343daea700ca26cf38fd90
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM120B CFAP300 FHOD3 GYPA CD200R1L	3.18e-05	168	96	5	17fb9426eeea407b26fb895b8397faca95b7552d
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM120B CFAP300 FHOD3 GYPA CD200R1L	3.18e-05	168	96	5	a61b39884851384cffd430079040546d125b2b40
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MROH2A SKA2 CCDC168 POLQ MAD2L1	3.18e-05	168	96	5	a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRC8C ATP8A1 FHOD1 TTC21B PLXNA2	3.65e-05	173	96	5	66488d01e03264fb193285470901c9c4182fbae8
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	DDIT4L COX10 TIAM2 ATP8A1 SOS1	3.65e-05	173	96	5	b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD244 ITGAD STAT4 CD200R1L MAD2L1	3.86e-05	175	96	5	ae7e0448ffd11b8908d0f6d99ff737faf5eca4bf
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-MAIT_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD244 PLXND1 ADAM12 LYST STAT4	4.19e-05	178	96	5	0290868dc990878eac5c182fe64968333bc52450
ToppCell	COVID-19-kidney-NK\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CD244 RAP1GAP2 LYST STAT4 ATP8A1	4.53e-05	181	96	5	8906ee8a7a1616dfe8c3b5c73988416641213629
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RALGAPA1 USP24 CHD2 STAT4 ATP8A1	5.43e-05	188	96	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	droplet-Marrow-nan-3m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM120B GCLC GYPA ALDH1A1 POLQ	5.56e-05	189	96	5	8a38baee58a27c2fa3f4bd131ab9f15723ed9295
ToppCell	Severe-Lymphoid-T-NK\|Severe / Condition, Lineage, Cell class and cell subclass	OR4K17 SKA2 STAT4 ATP8A1 POLQ	5.70e-05	190	96	5	60642de433f84fa2cecd796c3a1a4aab9219d3db
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	USP24 RAP1GAP2 FHOD3 ATP8A1 SLC35B4	5.70e-05	190	96	5	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD244 DDIT4L LYST STAT4 ATP8A1	6.14e-05	193	96	5	778fcf8448e81fe18972d97ea8a30ab036d16fe5
ToppCell	MS-CD8\|MS / Condition, Cell_class and T cell subcluster	CD244 LYST STAT4 ATP8A1 TPRG1	6.30e-05	194	96	5	8dfeaa213403cedecb1976bfde1bac84f0155999
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	CD244 STAT4 ARRB2 ATP8A1 TPRG1	6.30e-05	194	96	5	68e9ad254fe94e2f59cf5c2b2ea3e1245cb85104
ToppCell	tumor_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th\|tumor_Lung / Location, Cell class and cell subclass	RALGAPA1 PRPF38B STAT4 ATP8A1 PGAP1	6.77e-05	197	96	5	de26ca046038e34790cece24529a05d491e6f8ef
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RALGAPA1 USP24 CHD2 STAT4 PGAP1	7.10e-05	199	96	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Caecum-T_cell-CD8_T\|Caecum / Region, Cell class and subclass	CD244 LYST STAT4 ATP8A1 TPRG1	7.27e-05	200	96	5	8c0ced6cbfde40c2a9b54953c6fe93d83ad001d7
ToppCell	Sigmoid-Dendritic_cell-cycling_DCs\|Dendritic_cell / Region, Cell class and subclass	SKA2 SDAD1 NUP205 POLQ MAD2L1	7.27e-05	200	96	5	372fe9018481a4e9ac6ab3af43705a48238c4376
ToppCell	Caecum-(1)_T_cell-(10)_CD8_T\|Caecum / shred on region, Cell_type, and subtype	CD244 LYST STAT4 ATP8A1 TPRG1	7.27e-05	200	96	5	4276d8e21a1bb3cf51f238455bb072a7600f9253
ToppCell	mLN-T_cell-CD8_T\|T_cell / Region, Cell class and subclass	CD244 LYST STAT4 ATP8A1 TPRG1	7.27e-05	200	96	5	650916c6d2bcf00315c7a21088cb63f37bf24346
ToppCell	(10)_CD8_T\|World / shred on Cell_type and subtype	CD244 LYST STAT4 ATP8A1 TPRG1	8.17e-05	205	96	5	87c36989d0fc926f36d6b911ede068455f027177
Drug	cinchonidine	SLC47A2 SLC47A1	1.72e-05	2	95	2	ctd:C041622
Drug	ethohexadiol	SLC47A2 SLC47A1	1.72e-05	2	95	2	ctd:C004917
Drug	Sulfamerazine	SLC47A2 SLC47A1	1.72e-05	2	95	2	ctd:D013416
Drug	Midodrine	SLC47A2 SLC47A1	1.72e-05	2	95	2	ctd:D008879
Drug	triethylmethylammonium	SLC47A2 SLC47A1	1.72e-05	2	95	2	ctd:C043900
Drug	Nialamide	SLC47A2 SLC47A1	1.72e-05	2	95	2	ctd:D009526
Disease	lung carcinoma, asbestos exposure measurement	PTH2R PPL	9.83e-06	2	93	2	EFO_0001071, EFO_0004806
Disease	lymphocyte count	LRRC8C IL31RA TMEM120B OLFM4 RAP1GAP2 PLXND1 CHML ARHGEF11 HORMAD1 LYST ARRB2 GYPA USP7 SLC47A1 PLEC	5.15e-05	1464	93	15	EFO_0004587
Disease	Drug habituation	FHOD3 TIAM2 TTC21B TMPRSS7	4.89e-04	115	93	4	C0013170
Disease	Substance-Related Disorders	FHOD3 TIAM2 TTC21B TMPRSS7	4.89e-04	115	93	4	C0236969
Disease	Drug abuse	FHOD3 TIAM2 TTC21B TMPRSS7	4.89e-04	115	93	4	C0013146
Disease	Drug Use Disorders	FHOD3 TIAM2 TTC21B TMPRSS7	4.89e-04	115	93	4	C0013222
Disease	Drug Dependence	FHOD3 TIAM2 TTC21B TMPRSS7	4.89e-04	115	93	4	C1510472
Disease	Substance Dependence	FHOD3 TIAM2 TTC21B TMPRSS7	4.89e-04	115	93	4	C0038580
Disease	Substance Use Disorders	FHOD3 TIAM2 TTC21B TMPRSS7	4.89e-04	115	93	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	FHOD3 TIAM2 TTC21B TMPRSS7	4.89e-04	115	93	4	C0029231
Disease	Prescription Drug Abuse	FHOD3 TIAM2 TTC21B TMPRSS7	4.89e-04	115	93	4	C4316881
Disease	Substance abuse problem	FHOD3 TIAM2 TTC21B TMPRSS7	5.06e-04	116	93	4	C0740858
Disease	phenylacetylglutamine measurement	SYCP2 RXFP2	6.35e-04	12	93	2	EFO_0021013
Disease	sporadic amyotrophic lateral sclerosis	LRRC8C OLFM4 PTH2R PLXNA1	1.02e-03	140	93	4	EFO_0001357
Disease	insomnia, total blood protein measurement	OR4K17 MROH2A CD200R1L HSP90AA4P	1.26e-03	148	93	4	EFO_0004536, EFO_0004698
Disease	platelet crit	TMEM120B ITGAD ARHGEF11 NUP205 SLC35B4 GYPA USP7 PLEC MOV10	3.12e-03	952	93	9	EFO_0007985

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLQTVFLIAKVKYLS	TTC21B	491	Q7Z4L5
IITLYISAIKALRVL	ANAPC2	396	Q9UJX6
LESYKKYILVSLILL	COPS3	221	Q9UNS2
VKLIKSGAYVALTLL	ARHGEF11	106	O15085
SERKYVINISLILKI	ARHGEF33	276	A8MVX0
ILARLSKIKLTALVV	COX10	156	Q12887
VLLTDLKIQYTKIFI	ALDH1A1	11	P00352
VVYLKRKTLIRLLFT	ADAM12	726	O43184
LVKKKLYSLIGTTVI	DDIT4L	176	Q96D03
LGILVSYRVKVKLVV	ARRB2	316	P32121
ASLLLDVVYKVIKRT	ATP8A1	1061	Q9Y2Q0
KLLYSQGLLIDLLIK	CHML	236	P26374
TLLLVSLSFLYLKEV	PATE4	6	P0C8F1
LYIILKKLLDFILKT	NUP205	1396	Q92621
LVVLSYTLILKTILK	OR6C65	211	A6NJZ3
DLLSVLLYLLVKTEI	ANKRD27	311	Q96NW4
LVILSYSYIIKTILK	OR6C70	211	A6NIJ9
ASVILISYLLIIKTI	OR9I1	211	Q8NGQ6
ISYLLIIKTILKVKS	OR9I1	216	Q8NGQ6
KTLVIIEKTYSLLLD	PATL1	521	Q86TB9
TLKSTYLKLRFLIDI	PAN2	1061	Q504Q3
KKLISLAYTLLTPLL	OR10A3	271	P58181
LTLLVTTDLELIKYL	MAD2L1	51	Q13257
LLILIILTVAYGLKK	IL31RA	531	Q8NI17
LSLLIILYVKLSLFV	CD200R1L	236	Q6Q8B3
LLLVIVAVLIAYKRK	PLXNA1	1256	Q9UIW2
IIVIIVLIAYKRKSR	PLXNA2	1251	O75051
KKVLPEIYLTRLLST	PLXND1	1696	Q9Y4D7
ALIVLSYVLILKTIL	OR51A7	211	Q8NH64
SYVLILKTILSIASL	OR51A7	216	Q8NH64
LDVLLTLLSYVLTLK	OR51H1	211	Q8NH63
ILLISYSLILITIKN	OR4K17	216	Q8NGC6
ILLISYSIILVSLRK	OR4S2	211	Q8NH73
TLQKVLDSEKLLYVL	PPL	71	O60437
VLLTRVILSYKLDFL	GCLC	446	P48506
TTLRKVLKLNLTPYL	DNAH12	796	Q6ZR08
YLYTTIVSKILKILI	DNAH12	1731	Q6ZR08
EKTYVKRLVKILLLG	GNA13	41	Q14344
LVILSYAFIIKTILK	OR2AP1	211	Q8NGE2
KVLIKITYITELSIL	PARP4	726	Q9UKK3
LISYTIILFTILEKK	OR5H6	231	Q8NGV6
ALLLLALITATLYKL	ITGAD	1111	Q13349
IIISYTRVLFDILKK	OR5AC2	216	Q9NZP5
LKISTLRKLVDFLYT	BTBD18	81	B2RXH4
LETTKLIYKDLVSVR	CFAP300	191	Q9BRQ4
FETIILLTKELELYK	GTPBP10	251	A4D1E9
ALITTYEILLKDKTV	CHD2	591	O14647
VVCKKLRSITDVYLL	CCR8	61	P51685
ELLLTKICYITRKSA	POLQ	231	O75417
VVKTALKLLLVFVEY	FHOD3	206	Q2V2M9
TILLISYGIRRLIKK	GYPA	106	P02724
IYVKTLPILLKSRVI	LYST	776	Q99698
LVIVVTLYKKSYLLT	GPR161	46	Q8N6U8
SVKDLVILLYETALL	HSP90AA4P	346	Q58FG1
TKKASILLIRKIYIL	HORMAD1	146	Q86X24
VSLIRKISKELYVTL	CCDC168	5731	Q8NDH2
IRSKIVIEQLYAKLS	FAM186A	331	A6NE01
RLVVKTALKLLLVFV	FHOD1	216	Q9Y613
VTLILLLLLKVYQGK	CD244	6	Q9BZW8
LADKILISILYVSLT	CRLS1	171	Q9UJA2
KATLLIYTKTLLLPV	DPY19L2P2	296	Q6ZN68
YSKSLIKLLLGIDIL	FANCD2	131	Q9BXW9
LKVAVLLLLSYVLLR	ITPRIPL2	51	Q3MIP1
ILSSYVLKTVLLAVL	ITPRIPL2	401	Q3MIP1
ASKVEVLLLELLYKT	MROH2A	701	A6NES4
IEYLRVILRSKLKTV	RAP1GAP2	191	Q684P5
ILGIIILKKRYSIFK	SLC35B4	106	Q969S0
LLKELSVIKSRYQTL	SKA2	46	Q8WVK7
VFLLLYIVLKKLHLE	SLC47A2	261	Q86VL8
KFKLYLTIILLLGAV	TMEM120B	131	A0PK00
DVYIRIASLLKTLLK	POFUT2	61	Q9Y2G5
KKLQEYRVLITTLIT	MOV10	611	Q9HCE1
ALLILSLISYVSLKK	ST8SIA3	21	O43173
LLLTYLTLEKFLVIV	RXFP2	511	Q8WXD0
KAELLPTIKYLTLRL	PGAP1	416	Q75T13
YDIRLKLTKEVLTIQ	SNTG2	41	Q9NY99
KLLRKTLYTHIVTDI	SDAD1	131	Q9NVU7
IKAGTVIKLIERLTY	SOS1	601	Q07889
LISVYEKKLLNLTVR	OLFM4	126	Q6UX06
LVILSYTCIIKTILK	OR6C6	211	A6NF89
TLALLLFLYILGKKL	SLC47A1	226	Q96FL8
LQKSLPYILILSVKL	RNFT1	151	Q5M7Z0
LEALLKYIVIQVKSL	RALGAPA1	211	Q6GYQ0
RVLKYPLLLKELVSL	TIAM2	1251	Q8IVF5
KLVAIVGYLIRLSIK	TMPRSS7	276	Q7RTY8
VIQKFVLLILKRKTY	SLC25A46	281	Q96AG3
TLIQFTVKLRLLIKL	STAT4	336	Q14765
YSIEVRESKKLLTII	SYCP2	341	Q9BX26
LLYKLFTLKLTRKQV	PRPF38B	131	Q5VTL8
RILLVTDKTLLICKY	TPRG1	111	Q6ZUI0
YSTKITIPVIKRLLL	TAAR2	151	Q9P1P5
ESTKYLLLTSIVLRI	TMEM168	121	Q9H0V1
YLEKLKTISLVIRGT	PLEC	1221	Q15149
KQYRKLAKSTLVLVL	PTH2R	356	P49190
YRSTKLVIIERLLLL	USP24	916	Q9UPU5
LKTIGISKIYIDLIR	SLC9C2	171	Q5TAH2
YVLESTLKIIILKRK	SLC9C2	651	Q5TAH2
SGKLRLLEIVSYKII	USP7	936	Q93009
LSKYHIVSKLLALLL	TERB1	291	Q8NA31
LILGALLVSYLAVKK	ZP4	516	Q12836
TVLKVIKFLIIIAYN	LRRC8C	266	Q8TDW0
VRKKTSYVGLVLVLL	N4BP2	431	Q86UW6