Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

HSPG2 COL27A1 MATN3 LAMA1 SSPOP FBN1 FBN2 LTBP4 MUC5AC AGRN FBN3

1.97e-0718815111GO:0005201
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF672 ZNF586 ZEB1 ZNF680 ZSCAN9 SUV39H2 ZNF891 GFI1 ZNF691 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 NEUROG1 ZSCAN20 SARS1 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

4.25e-07145915130GO:0000977
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF672 ZNF586 ZEB1 ZNF680 ZSCAN9 ZNF891 GFI1 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 NEUROG1 ZSCAN20 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98 MYRF NOTCH1

7.04e-07141215129GO:0000981
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF586 ZEB1 ZNF680 ZSCAN9 CXXC1 GFI1 ZNF691 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 NEUROG1 ZSCAN20 SARS1 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF506 UHRF1 ZNF814 ZNF91 ZNF418 ZNF98 NOTCH1

9.56e-07127115127GO:0000987
GeneOntologyMolecularFunctioncalcium ion binding

SELL SELP HSPG2 STAB2 DSG2 MATN3 TTYH2 ADAMTS13 ITPR1 STAB1 EDEM3 FBN1 FBN2 LRP1 LRP2 LTBP4 AGRN FBN3 NOTCH1

3.93e-0674915119GO:0005509
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

STAB2 STAB1 LRP1 LRP2

5.33e-06161514GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

STAB2 STAB1 LRP1 LRP2

1.70e-05211514GO:0030228
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF586 ZEB1 ZNF680 ZSCAN9 GFI1 ZNF691 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 NEUROG1 ZSCAN20 SARS1 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF506 ZNF814 ZNF91 ZNF418 ZNF98

2.09e-05124415124GO:0000978
GeneOntologyMolecularFunctionglycosaminoglycan binding

MPO SELL SELP STAB2 STAB1 FBN1 MAMDC2 FURIN LTBP4 AGRN

3.82e-0526815110GO:0005539
GeneOntologyMolecularFunctionglycosphingolipid binding

SELL SELP LAMA1

1.15e-04131513GO:0043208
GeneOntologyMolecularFunctionsphingolipid binding

SELL SELP LAMA1 MAP3K1

1.22e-04341514GO:0046625
GeneOntologyMolecularFunctiongrowth factor binding

ERBB4 HTRA1 FURIN SCN5A LRP2 LTBP4 AGRN

1.87e-041561517GO:0019838
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

HSPG2 LRP1 LRP2 PCSK9

2.10e-04391514GO:0070325
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

STAB2 STAB1 PCSK9

3.18e-04181513GO:0030169
GeneOntologyMolecularFunctionsialic acid binding

SELL SELP AGRN

8.63e-04251513GO:0033691
GeneOntologyMolecularFunctionscavenger receptor activity

STAB2 STAB1 LRP1

1.09e-03271513GO:0005044
GeneOntologyMolecularFunctionzinc ion binding

PAPPA2 ZEB1 PRICKLE1 MARCHF8 KCMF1 CUL9 ERVK-7 ADAMTS13 SUV39H2 CXXC1 MEFV POLR1H MAP3K1 P2RX4 UHRF1 ZNF91

1.19e-0389115116GO:0008270
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

HTRA1 ZEB1 FBN1 FBN2 ZFYVE9 FURIN LRP1 SPRED1 LTBP4

1.30e-051921529GO:0017015
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

HTRA1 ZEB1 FBN1 FBN2 ZFYVE9 FURIN LRP1 SPRED1 LTBP4

1.47e-051951529GO:1903844
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

HTRA1 ZEB1 MAP3K1 FBN1 FBN2 ZFYVE9 FURIN LRP1 SPRED1 LTBP4

3.96e-0527615210GO:0007179
GeneOntologyBiologicalProcessheart development

HSPG2 ERBB4 NEBL DSG2 PRICKLE1 NSD2 OBSL1 C2CD3 FBN1 WNT16 SCN5A LRP1 LRP2 SPRED1 TNFRSF1A ZNF418 NOTCH1

4.46e-0575715217GO:0007507
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

HTRA1 ZEB1 FBN1 FBN2 ZFYVE9 FURIN LRP1 LRP2 SPRED1 LTBP4 NOTCH1

5.47e-0534715211GO:0090092
GeneOntologyBiologicalProcessextracellular matrix organization

HSPG2 PRICKLE1 COL27A1 MATN3 LAMA1 ADAMTS13 FURIN LRP1 TNFRSF1A LTBP4 NOTCH1

1.14e-0437715211GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

HSPG2 PRICKLE1 COL27A1 MATN3 LAMA1 ADAMTS13 FURIN LRP1 TNFRSF1A LTBP4 NOTCH1

1.17e-0437815211GO:0043062
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

HTRA1 ZEB1 MAP3K1 FBN1 FBN2 ZFYVE9 FURIN LRP1 LRP2 SPRED1 LTBP4 NOTCH1

1.17e-0444515212GO:0141091
GeneOntologyBiologicalProcessexternal encapsulating structure organization

HSPG2 PRICKLE1 COL27A1 MATN3 LAMA1 ADAMTS13 FURIN LRP1 TNFRSF1A LTBP4 NOTCH1

1.20e-0437915211GO:0045229
GeneOntologyBiologicalProcesscirculatory system development

HSPG2 PLK2 ERBB4 GGNBP2 STAB2 NEBL DSG2 PRICKLE1 NSD2 COL27A1 LAMA1 OBSL1 STAB1 C2CD3 FBN1 SARS1 WNT16 SCN5A LRP1 LRP2 SPRED1 TNFRSF1A ZNF418 NOTCH1

1.43e-04144215224GO:0072359
GeneOntologyBiologicalProcesscardiac muscle tissue development

HSPG2 ERBB4 NEBL DSG2 PRICKLE1 OBSL1 SCN5A LRP2 ZNF418 NOTCH1

1.61e-0432715210GO:0048738
GeneOntologyBiologicalProcessextracellular matrix constituent secretion

PRICKLE1 TNFRSF1A NOTCH1

1.67e-04151523GO:0070278
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

HTRA1 ZEB1 MAP3K1 FBN1 FBN2 ZFYVE9 FURIN LRP1 SPRED1 LTBP4

2.00e-0433615210GO:0071560
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

HTRA1 ZEB1 MAP3K1 FBN1 FBN2 ZFYVE9 FURIN LRP1 SPRED1 LTBP4

2.36e-0434315210GO:0071559
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

HTRA1 ZEB1 MAP3K1 FBN1 FBN2 ZFYVE9 FURIN LRP1 LRP2 SPRED1 LTBP4 NOTCH1

2.45e-0448215212GO:0007178
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

HTRA1 ZEB1 FBN1 FBN2 ZFYVE9 FURIN LRP1 LRP2 SPRED1 LTBP4 NOTCH1

2.47e-0441215211GO:0090287
GeneOntologyCellularComponentmicrofibril

FBN1 FBN2 LTBP4 FBN3

1.83e-06131524GO:0001527
GeneOntologyCellularComponentextracellular matrix

HSPG2 HTRA1 COL20A1 WNT3 COL27A1 MATN3 LAMA1 ADAMTS13 SSPOP TF FBN1 FBN2 MAMDC2 LTBP4 MUC5AC AGRN FBN3

6.03e-0665615217GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

HSPG2 HTRA1 COL20A1 WNT3 COL27A1 MATN3 LAMA1 ADAMTS13 SSPOP TF FBN1 FBN2 MAMDC2 LTBP4 MUC5AC AGRN FBN3

6.28e-0665815217GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

HSPG2 HTRA1 COL20A1 COL27A1 MATN3 LAMA1 SSPOP TF FBN1 FBN2 MAMDC2 LTBP4 AGRN

1.37e-0453015213GO:0062023
GeneOntologyCellularComponentendoplasmic reticulum lumen

COL20A1 WNT3 COL27A1 MATN3 ADAMTS13 TF EDEM3 FBN1 FURIN PCSK9

1.63e-0433215210GO:0005788
GeneOntologyCellularComponentplatelet dense granule membrane

SELP ITPR1

7.73e-0461522GO:0031088
MousePhenoabnormal mandible morphology

PAPPA2 HSPG2 ZEB1 PRICKLE1 COL27A1 FBN1 FBN2 SPRED1 GCN1

1.45e-051761159MP:0000458
Domainzf-C2H2_6

ZNF672 ZNF586 ZNF680 ZSCAN9 ZNF891 GFI1 ZNF71 ZNF419 ZNF514 ZNF718 ZNF728 ZNF735 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

1.16e-1231415220PF13912
DomainGrowth_fac_rcpt_

HSPG2 ERBB4 HTRA1 STAB2 MATN3 LAMA1 STAB1 FBN1 FBN2 FURIN LRP1 LRP2 LTBP4 FBN3 NOTCH1

2.54e-1215615215IPR009030
Domain-

ZNF672 ZNF586 ZEB1 ZNF680 ZSCAN9 ZNF891 GFI1 ZNF691 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 ZSCAN20 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

7.24e-12679152273.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

ZNF672 ZNF586 ZEB1 ZNF680 ZSCAN9 ZNF891 GFI1 ZNF691 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 ZSCAN20 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

1.20e-1169415227IPR013087
DomainZINC_FINGER_C2H2_2

ZNF672 ZNF586 ZEB1 ZNF680 KCMF1 ZSCAN9 ZNF891 GFI1 ZNF691 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 ZSCAN20 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

2.69e-1177515228PS50157
DomainZINC_FINGER_C2H2_1

ZNF672 ZNF586 ZEB1 ZNF680 KCMF1 ZSCAN9 ZNF891 GFI1 ZNF691 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 ZSCAN20 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

2.86e-1177715228PS00028
DomainZnf_C2H2-like

ZNF672 ZNF586 ZEB1 ZNF680 KCMF1 ZSCAN9 ZNF891 GFI1 ZNF691 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 ZSCAN20 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

5.02e-1179615228IPR015880
DomainEGF_2

SELL SELP HSPG2 STAB2 MATN3 LAMA1 ADAM29 SSPOP STAB1 FBN1 FBN2 LRP1 LRP2 LTBP4 AGRN FBN3 NOTCH1

5.68e-1126515217PS01186
DomainZnf_C2H2

ZNF672 ZNF586 ZEB1 ZNF680 KCMF1 ZSCAN9 ZNF891 GFI1 ZNF691 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 ZSCAN20 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

6.51e-1180515228IPR007087
Domainzf-C2H2

ZNF672 ZNF586 ZNF680 ZSCAN9 ZNF891 GFI1 ZNF691 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 ZSCAN20 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

6.70e-1169315226PF00096
DomainZnF_C2H2

ZNF672 ZNF586 ZEB1 ZNF680 KCMF1 ZSCAN9 ZNF891 GFI1 ZNF691 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 ZSCAN20 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

7.09e-1180815228SM00355
DomainEGF_3

SELL SELP HSPG2 STAB2 MATN3 ADAM29 SSPOP STAB1 FBN1 FBN2 LRP1 LRP2 LTBP4 AGRN FBN3 NOTCH1

8.90e-1123515216PS50026
DomainKRAB

ZNF586 ZNF680 ZNF891 ZNF419 ZNF514 ZNF716 ZSCAN20 ZNF718 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

1.74e-1036915219SM00349
DomainKRAB

ZNF586 ZNF680 ZNF891 ZNF419 ZNF514 ZNF716 ZSCAN20 ZNF718 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

1.82e-1037015219IPR001909
DomainEGF-like_dom

SELL SELP HSPG2 STAB2 MATN3 LAMA1 ADAM29 STAB1 FBN1 FBN2 LRP1 LRP2 LTBP4 AGRN FBN3 NOTCH1

2.10e-1024915216IPR000742
DomainEGF_1

SELL SELP HSPG2 STAB2 LAMA1 ADAM29 SSPOP STAB1 FBN1 FBN2 LRP1 LRP2 LTBP4 AGRN FBN3 NOTCH1

2.99e-1025515216PS00022
DomainEGF_CA

HSPG2 STAB2 MATN3 STAB1 FBN1 FBN2 LRP1 LRP2 LTBP4 AGRN FBN3 NOTCH1

3.28e-1012215212SM00179
DomainEGF-like_Ca-bd_dom

HSPG2 STAB2 MATN3 STAB1 FBN1 FBN2 LRP1 LRP2 LTBP4 AGRN FBN3 NOTCH1

3.97e-1012415212IPR001881
DomainEGF-like_CS

SELL SELP HSPG2 STAB2 MATN3 LAMA1 ADAM29 STAB1 FBN1 FBN2 LRP1 LRP2 LTBP4 AGRN FBN3 NOTCH1

4.20e-1026115216IPR013032
DomainKRAB

ZNF586 ZNF680 ZNF891 ZNF419 ZNF514 ZNF716 ZNF718 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

7.94e-1035815218PS50805
DomainKRAB

ZNF586 ZNF680 ZNF891 ZNF419 ZNF514 ZNF716 ZNF718 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

7.94e-1035815218PF01352
DomainEGF

SELL SELP HSPG2 STAB2 MATN3 LAMA1 STAB1 FBN1 FBN2 LRP1 LRP2 LTBP4 AGRN FBN3 NOTCH1

8.72e-1023515215SM00181
DomainEGF

SELL SELP HSPG2 STAB2 MATN3 STAB1 LRP1 LRP2 AGRN FBN3 NOTCH1

6.56e-0912615211PF00008
DomainTB

FBN1 FBN2 LTBP4 FBN3

1.45e-0771524PF00683
Domain-

FBN1 FBN2 LTBP4 FBN3

2.88e-07815243.90.290.10
DomainEGF_CA

MATN3 FBN1 FBN2 LRP1 LRP2 LTBP4 FBN3 NOTCH1

4.96e-07861528PF07645
DomainTB_dom

FBN1 FBN2 LTBP4 FBN3

5.15e-0791524IPR017878
DomainTB

FBN1 FBN2 LTBP4 FBN3

5.15e-0791524PS51364
DomainFBN

FBN1 FBN2 FBN3

5.29e-0731523IPR011398
DomaincEGF

FBN1 FBN2 LRP1 LRP2 FBN3

1.92e-06261525PF12662
DomaincEGF

FBN1 FBN2 LRP1 LRP2 FBN3

1.92e-06261525IPR026823
DomainEGF_LAM_2

HSPG2 STAB2 LAMA1 STAB1 AGRN

4.04e-06301525PS50027
DomainEGF_LAM_1

HSPG2 STAB2 LAMA1 STAB1 AGRN

4.04e-06301525PS01248
DomainEGF_Lam

HSPG2 STAB2 LAMA1 STAB1 AGRN

8.91e-06351525SM00180
DomainLaminin_EGF

HSPG2 STAB2 LAMA1 STAB1 AGRN

1.35e-05381525IPR002049
DomainEGF_Ca-bd_CS

FBN1 FBN2 LRP1 LRP2 LTBP4 FBN3 NOTCH1

1.43e-05971527IPR018097
DomainEGF_CA

FBN1 FBN2 LRP1 LRP2 LTBP4 FBN3 NOTCH1

1.64e-05991527PS01187
DomainASX_HYDROXYL

FBN1 FBN2 LRP1 LRP2 LTBP4 FBN3 NOTCH1

1.75e-051001527PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

FBN1 FBN2 LRP1 LRP2 LTBP4 FBN3 NOTCH1

2.56e-051061527IPR000152
DomainDUF3480

ZFYVE16 ZFYVE9

6.58e-0521522PF11979
DomainDUF3480

ZFYVE16 ZFYVE9

6.58e-0521522IPR022557
DomainZnf_FYVE_endofin

ZFYVE16 ZFYVE9

6.58e-0521522IPR017165
DomainConA-like_dom

PAPPA2 HSPG2 COL20A1 COL27A1 LAMA1 MEFV MAMDC2 AGRN SPSB3

7.83e-052191529IPR013320
DomainLaminin_G_1

HSPG2 LAMA1 AGRN

8.31e-05111523PF00054
DomainLaminin_G

HSPG2 COL20A1 COL27A1 LAMA1 AGRN

1.08e-04581525IPR001791
DomainTIL_dom

SSPOP LRP2 MUC5AC

1.80e-04141523IPR002919
DomainLaminin_EGF

HSPG2 LAMA1 STAB1 AGRN

1.81e-04351524PF00053
DomainSelectin_superfamily

SELL SELP

1.96e-0431522IPR002396
DomainLAM_G_DOMAIN

HSPG2 COL27A1 LAMA1 AGRN

2.51e-04381524PS50025
DomainLDLR_class-A_CS

HSPG2 SSPOP LRP1 LRP2

3.07e-04401524IPR023415
DomainFAS1

STAB2 STAB1

3.91e-0441522SM00554
DomainFAS1_domain

STAB2 STAB1

3.91e-0441522IPR000782
Domain-

STAB2 STAB1

3.91e-04415222.30.180.10
DomainFAS1

STAB2 STAB1

3.91e-0441522PS50213
DomainFasciclin

STAB2 STAB1

3.91e-0441522PF02469
Domain-

DCAF1 WSB1 CFAP43 TEP1 BIRC6 SCAP WDR75 PAN2 WDR90 MAPKBP1

4.07e-04333152102.130.10.10
DomainWD40/YVTN_repeat-like_dom

DCAF1 WSB1 CFAP43 TEP1 BIRC6 SCAP WDR75 PAN2 WDR90 MAPKBP1

4.27e-0433515210IPR015943
DomainLdl_recept_a

HSPG2 SSPOP LRP1 LRP2

4.85e-04451524PF00057
Domain-

HSPG2 SSPOP LRP1 LRP2

5.27e-044615244.10.400.10
DomainLDLRA_1

HSPG2 SSPOP LRP1 LRP2

6.21e-04481524PS01209
DomainLDrepeatLR_classA_rpt

HSPG2 SSPOP LRP1 LRP2

6.72e-04491524IPR002172
DomainLDLa

HSPG2 SSPOP LRP1 LRP2

6.72e-04491524SM00192
DomainLDLRA_2

HSPG2 SSPOP LRP1 LRP2

6.72e-04491524PS50068
DomainWD40_repeat_dom

DCAF1 WSB1 CFAP43 TEP1 SCAP WDR75 PAN2 WDR90 MAPKBP1

7.43e-042971529IPR017986
DomainPWWP

NSD2 PWWP2B PWWP3B

9.43e-04241523PS50812
DomainNotch_dom

PAPPA2 NOTCH1

1.35e-0371522IPR000800
Domainzf-Di19

ZEB1 KCMF1

1.35e-0371522PF05605
DomainDi19_Zn_binding_dom

ZEB1 KCMF1

1.35e-0371522IPR008598
DomainNotch

PAPPA2 NOTCH1

1.35e-0371522PF00066
DomainNL

PAPPA2 NOTCH1

1.35e-0371522SM00004
DomainEGF_extracell

STAB2 STAB1 LRP2 NOTCH1

1.44e-03601524IPR013111
DomainEGF_2

STAB2 STAB1 LRP2 NOTCH1

1.44e-03601524PF07974
DomainhEGF

FBN2 FBN3 NOTCH1

1.49e-03281523PF12661
DomainLAMININ_IVA

HSPG2 LAMA1

1.78e-0381522PS51115
DomainLaminin_B

HSPG2 LAMA1

1.78e-0381522PF00052
DomainLamB

HSPG2 LAMA1

1.78e-0381522SM00281
DomainLaminin_IV

HSPG2 LAMA1

1.78e-0381522IPR000034
DomainWD_REPEATS_1

DCAF1 WSB1 CFAP43 TEP1 SCAP WDR75 WDR90 MAPKBP1

2.02e-032781528PS00678
DomainWD_REPEATS_2

DCAF1 WSB1 CFAP43 TEP1 SCAP WDR75 WDR90 MAPKBP1

2.06e-032791528PS50082
DomainWD_REPEATS_REGION

DCAF1 WSB1 CFAP43 TEP1 SCAP WDR75 WDR90 MAPKBP1

2.06e-032791528PS50294
DomainPeptidase_S8_subtilisin-rel

FURIN PCSK9

2.84e-03101522IPR015500
DomainSUBTILASE_ASP

FURIN PCSK9

2.84e-03101522PS00136
DomainSUBTILASE_HIS

FURIN PCSK9

2.84e-03101522PS00137
DomainSUBTILASE_SER

FURIN PCSK9

2.84e-03101522PS00138
Domain-

FURIN PCSK9

3.45e-031115223.40.50.200
DomainGFP-like

STAB2 STAB1

3.45e-03111522IPR023413
DomainPeptidase_S8/S53_dom

FURIN PCSK9

3.45e-03111522IPR000209
Domain-

STAB2 STAB1

3.45e-031115222.40.155.10
DomainPeptidase_S8

FURIN PCSK9

3.45e-03111522PF00082
DomainEGF_dom

STAB2 STAB1

4.12e-03121522IPR024731
DomainC8

SSPOP MUC5AC

4.12e-03121522PF08742
DomainEGF_3

STAB2 STAB1

4.12e-03121522PF12947
DomainTIL

SSPOP MUC5AC

4.12e-03121522PF01826
DomainLink_dom

STAB2 STAB1

4.84e-03131522IPR000538
DomainSSD

SCAP DISP3

4.84e-03131522IPR000731
DomainXlink

STAB2 STAB1

4.84e-03131522PF00193
DomainSSD

SCAP DISP3

4.84e-03131522PS50156
DomainLINK_2

STAB2 STAB1

4.84e-03131522PS50963
DomainLINK

STAB2 STAB1

4.84e-03131522SM00445
DomainUnchr_dom_Cys-rich

SSPOP MUC5AC

4.84e-03131522IPR014853
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

HSPG2 HTRA1 COL20A1 COL27A1 MATN3 LAMA1 FBN1 FBN2 FURIN LTBP4 AGRN FBN3

8.63e-0630011912M610
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2 FURIN LTBP4 FBN3

3.29e-05441195M26969
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HSPG2 NSD2 PEX6 CUL9 CFAP43 ANKHD1 TEP1 BIRC6 FOCAD PLEKHG1 C2CD3 PWWP2B SCAP FURIN SCN5A DIP2C WDR90 MAPKBP1 LTBP4 GCN1 MYRF AGRN NOTCH1

7.59e-1011051542335748872
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DCAF1 ERBB4 ACTR8 HTRA1 WAPL DSG2 NSD2 OBSL1 PEX6 CUL9 ANKHD1 TEP1 TF EDEM3 PWWP2B FBN2 DDX18 SCN5A LRP1 LRP2 LTBP4 ARAP2

4.95e-0911161542231753913
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN2 FBN3

3.39e-074154325034023
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

FBN1 FBN2 LTBP4

3.39e-074154312429738
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

SSPOP FBN1 FBN2 LRP1 LRP2 MUC5AC

7.72e-0771154633541421
Pubmed

Development, composition, and structural arrangements of the ciliary zonule of the mouse.

HSPG2 FBN1 FBN2

8.46e-075154323493297
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

HSPG2 COL27A1 LAMA1 SSPOP FBN1 FBN2 LTBP4 AGRN

1.22e-06175154828071719
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF680 ZNF419 ZNF718 ZNF728 ZNF558 ZNF91 ZNF98 GCN1

1.57e-06181154837372979
Pubmed

Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.

HSPG2 LAMA1 AGRN

1.69e-066154315668394
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DCAF1 ZFYVE16 OBSL1 CUL9 FOCAD PLEKHG1 STARD9 NAV3 MAPKBP1 ARAP2 PDZD2

2.22e-064071541112693553
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

HSPG2 LAMA1 FBN1 FBN2 AGRN

2.88e-0650154523658023
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

HSPG2 ANKHD1 TEP1 SSPOP CXXC1 GFI1 POLR1H LRP2 TMF1 MAPKBP1 LTBP4 AGRN NOTCH1

3.46e-066081541316713569
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

SELP ERBB4 LRP1 LRP2 TNFRSF1A NOTCH1

6.12e-06101154623382219
Pubmed

Effect of tumour necrosis factor-alpha receptor 1 genetic deletion on carrageenan-induced acute inflammation: a comparison with etanercept.

MPO SELP TNFRSF1A

7.01e-069154318505433
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF716 ZNF718 ZNF506 ZNF91

8.05e-0629154414563677
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

HSPG2 COL20A1 LAMA1 SSPOP AGRN

9.85e-0664154522261194
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

HSPG2 HTRA1 COL27A1 LAMA1 FBN1 LTBP4 AGRN

1.02e-05167154722159717
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

HSPG2 FBN1 LRP1 LTBP4 AGRN NOTCH1

1.50e-05118154621078624
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ZFYVE16 DSG2 PEX6 RTN3 ITPR1 SCAP ZFYVE9 FURIN LRP2 TMF1 PLEKHM3

1.66e-055041541134432599
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DLGAP1 PLK2 ACTR8 WAPL CEP85 OBSL1 CUL9 TF STAB1 FOCAD FBN1 DDX18 ZNF558 NAV3 LRP1 LRP2 SPRED1 ZNF439

1.67e-0512851541835914814
Pubmed

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.

HSPG2 LAMA1 AGRN

1.82e-0512154316750824
Pubmed

Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.

FBN1 FBN2

1.95e-052154212399449
Pubmed

Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.

FBN1 FBN2

1.95e-052154221851253
Pubmed

New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.

FBN1 FBN2

1.95e-052154230044367
Pubmed

Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.

FBN1 FBN2

1.95e-052154221440062
Pubmed

Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma.

HSPG2 AGRN

1.95e-052154225506919
Pubmed

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.

FBN1 FBN2

1.95e-052154215131124
Pubmed

The maternal protein NLRP5 stabilizes UHRF1 in the cytoplasm: implication for the pathogenesis of multilocus imprinting disturbance.

UHRF1 NLRP5

1.95e-052154238868925
Pubmed

FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.

STAB2 STAB1

1.95e-052154212473645
Pubmed

TNFRSF1A and MEFV mutations in childhood onset multiple sclerosis.

MEFV TNFRSF1A

1.95e-052154228927886
Pubmed

The association of TNFRSF1A gene and MEFV gene mutations with adult onset Still's disease.

MEFV TNFRSF1A

1.95e-052154223269568
Pubmed

Role of selectins in experimental Staphylococcus aureus-induced arthritis.

SELL SELP

1.95e-052154210898496
Pubmed

Microfibril structure masks fibrillin-2 in postnatal tissues.

FBN1 FBN2

1.95e-052154220404337
Pubmed

Autoinflammatory diseases and cardiovascular manifestations.

MEFV TNFRSF1A

1.95e-052154221284530
Pubmed

Fibrillln mutations in Marfan syndrome and related phenotypes.

FBN1 FBN2

1.95e-05215428791520
Pubmed

Specific glycoforms of MUC5AC and endorepellin accurately distinguish mucinous from nonmucinous pancreatic cysts.

HSPG2 MUC5AC

1.95e-052154223836919
Pubmed

Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.

FBN1 FBN2

1.95e-05215428307578
Pubmed

Platelet, not endothelial, P-selectin expression contributes to generation of immunity in cutaneous contact hypersensitivity.

SELL SELP

1.95e-052154220056837
Pubmed

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

FBN1 FBN2

1.95e-05215427744963
Pubmed

Fibrillin microfibrils in bone physiology.

FBN1 FBN2

1.95e-052154226408953
Pubmed

Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver.

STAB2 STAB1

1.95e-052154221427291
Pubmed

Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.

FBN1 FBN2

1.95e-052154218006876
Pubmed

Digenic MEFV/TNFRSF1A autoinflammatory syndrome with relapsing aseptic neutrophilic meningitis and chronic myelitis.

MEFV TNFRSF1A

1.95e-052154228134085
Pubmed

Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.

FBN1 FBN2

1.95e-052154224833718
Pubmed

The Notch1 receptor is cleaved constitutively by a furin-like convertase.

FURIN NOTCH1

1.95e-05215429653148
Pubmed

Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding.

STAB2 STAB1

1.95e-052154215572036
Pubmed

Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin-deficient mice.

STAB2 STAB1

1.95e-052154238946049
Pubmed

Exome sequencing identified new mutations in a Marfan syndrome family.

FBN1 LRP1

1.95e-052154224484584
Pubmed

Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins.

SELL SELP

1.95e-052154212093896
Pubmed

L- and P-selectins collaborate to support leukocyte rolling in vivo when high-affinity P-selectin-P-selectin glycoprotein ligand-1 interaction is inhibited.

SELL SELP

1.95e-052154215743805
Pubmed

Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.

FBN1 FBN2

1.95e-052154224265020
Pubmed

In vivo studies of mutant fibrillin-1 microfibrils.

FBN1 FBN2

1.95e-052154220529844
Pubmed

Postprandial activation of leukocyte-endothelium interaction by fatty acids in the visceral adipose tissue microcirculation.

MPO SELP

1.95e-052154231393790
Pubmed

MEFV gene polymorphisms and TNFRSF1A mutation in patients with inflammatory myopathy with abundant macrophages.

MEFV TNFRSF1A

1.95e-052154224965843
Pubmed

FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities.

STAB2 STAB1

1.95e-052154212077138
Pubmed

Clinical and genetic features of hereditary periodic fever syndromes in Hispanic patients: the Chilean experience.

MEFV TNFRSF1A

1.95e-052154222281876
Pubmed

Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.

FBN1 FBN2

1.95e-052154223133647
Pubmed

The low-density-lipoprotein receptor-related protein (LRP) is processed by furin in vivo and in vitro.

FURIN LRP1

1.95e-05215428546712
Pubmed

Selectin-mediated adhesion in shear flow using micropatterned substrates: multiple-bond interactions govern the critical length for cell binding.

SELL SELP

1.95e-052154222627390
Pubmed

Proprotein convertase subtilisin/kexin type 9 targets megalin in the kidney proximal tubule and aggravates proteinuria in nephrotic syndrome.

LRP2 PCSK9

1.95e-052154237406929
Pubmed

Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.

FBN1 FBN2

1.95e-05215421852206
Pubmed

Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA.

ZFYVE16 ZFYVE9

1.95e-052154216775010
Pubmed

Scavenging Endothelium of Pancreatic Islets: Differential Expression of Stabilin-1 and Stabilin-2 in Mice and Humans.

STAB2 STAB1

1.95e-052154227977633
Pubmed

AGRN promotes lung adenocarcinoma progression by activating Notch signaling pathway and acts as a therapeutic target.

AGRN NOTCH1

1.95e-052154237321467
Pubmed

Microfibrils at basement membrane zones interact with perlecan via fibrillin-1.

HSPG2 FBN1

1.95e-052154215657057
Pubmed

Mutational spectrum in the MEFV and TNFRSF1A genes in patients suffering from AA amyloidosis and recurrent inflammatory attacks.

MEFV TNFRSF1A

1.95e-052154212105243
Pubmed

Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.

FBN1 FBN2

1.95e-052154212429739
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

1.95e-052154234445520
Pubmed

Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study.

STAB2 STAB1

1.95e-052154233008099
Pubmed

Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells.

STAB2 STAB1

1.95e-052154233130055
Pubmed

Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.

FBN1 FBN2

1.95e-052154212524050
Pubmed

Comparative immunolocalisation of fibrillin-1 and perlecan in the human foetal, and HS-deficient hspg2 exon 3 null mutant mouse intervertebral disc.

HSPG2 FBN1

1.95e-052154223104139
Pubmed

Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis.

SELL SELP

1.95e-052154211854515
Pubmed

Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.

FBN1 FBN2

1.95e-05215428120105
Pubmed

The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.

FBN1 FBN2

1.95e-052154235419902
Pubmed

Role of the R92Q TNFRSF1A mutation in patients with familial Mediterranean fever.

MEFV TNFRSF1A

1.95e-052154220506103
Pubmed

Fibrillin assembly: dimer formation mediated by amino-terminal sequences.

FBN1 FBN2

1.95e-052154210504303
Pubmed

Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.

FBN1 FBN3

1.95e-052154215221638
Pubmed

Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan.

MPO HSPG2

1.95e-052154219788922
Pubmed

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.

STAB2 STAB1

1.95e-052154221293057
Pubmed

Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas.

SELL SELP

1.95e-052154212975470
Pubmed

Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues.

STAB2 STAB1

1.95e-052154211829752
Pubmed

The Fbn1 gene variant governs passive ascending aortic mechanics in the mgΔlpn mouse model of Marfan syndrome when superimposed to perlecan haploinsufficiency.

HSPG2 FBN1

1.95e-052154238545339
Pubmed

Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.

FBN1 FBN2

1.95e-052154225524144
Pubmed

PRICKLE1 × FOCAD Interaction Revealed by Genome-Wide vQTL Analysis of Human Facial Traits.

PRICKLE1 FOCAD

1.95e-052154234434215
Pubmed

[The analysis of the influence of short term physical effort on selected endothelial function parameters and blood vessels stiffness features among young and healthy men].

SELL SELP

1.95e-052154225095634
Pubmed

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

FBN1 FBN2

1.95e-052154216407178
Pubmed

Is HSPG2 a modifier gene for Marfan syndrome?

HSPG2 FBN1

1.95e-052154232514132
Pubmed

Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice.

STAB2 STAB1

1.95e-052154237446152
Pubmed

N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.

FBN1 FBN2

1.95e-052154210359653
Pubmed

Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment.

FURIN LRP1

1.95e-05215422112085
Pubmed

Protective effects of fucoidan, a P- and L-selectin inhibitor, in murine acute pancreatitis.

SELL SELP

1.95e-052154224177139
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

MPO SELL HSPG2 DSG2 ADAMTS13 TF LRP1 SERPINA7

2.05e-05257154816335952
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

HSPG2 LAMA1 AGRN

2.36e-0513154312682087
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

HSPG2 HTRA1 DSG2 LAMA1 RTN3 ITPR1 EDEM3 FBN1 FBN2 SCAP FURIN LRP1 UHRF1 TNFRSF1A AGRN NOTCH1 PCSK9

2.56e-0512011541735696571
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WAPL NSD2 UVSSA ARHGAP11A ANKHD1 GPATCH2L NUAK2 STAB1 PAN2 FAM53B WDR90

2.58e-055291541114621295
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

FURIN LRP1 LRP2

2.99e-0514154315082773
Pubmed

Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.

HSPG2 GC TF LRP1

4.37e-0544154431273033
Pubmed

Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.

HSPG2 LAMA1 AGRN

4.57e-0516154317948866
Pubmed

Congenital Diaphragmatic Hernia Overview

FBN1 LRP2 LTBP4 MYRF

5.22e-0546154420301533
InteractionNTN5 interactions

FBN1 FBN2 LRP2 LTBP4 NOTCH1

8.37e-07241515int:NTN5
InteractionZNF408 interactions

HSPG2 LAMA1 CXXC1 GPATCH2L FBN1 FBN2 LRP2 SPRED1 LTBP4

1.49e-061451519int:ZNF408
InteractionCUBN interactions

GC TF LRP1 LRP2

3.88e-06151514int:CUBN
InteractionZFP41 interactions

FBN1 FBN2 LRP1 LRP2 LTBP4 AGRN

4.24e-06571516int:ZFP41
Cytoband5q23-q31

FBN2 NEUROG1

1.12e-05215425q23-q31
Cytoband19q13.43

ZNF586 ZNF419 ZNF814 ZNF418 NLRP5

1.18e-0587154519q13.43
Cytoband1q23-q25

SELL PAPPA2

6.68e-05415421q23-q25
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF672 ZNF586 ZEB1 ZNF680 ZSCAN9 ZNF891 GFI1 ZNF691 ZNF71 ZNF419 BCL6B ZNF514 ZNF716 ZSCAN20 ZNF718 EGR4 ZNF728 ZNF735 ZKSCAN3 ZNF558 ZNF506 ZNF814 ZNF91 ZNF700 ZNF439 ZNF418 ZNF98

7.66e-147181172728
GeneFamilyCD molecules|Selectins|Sushi domain containing|C-type lectin domain containing

SELL SELP

1.24e-0431172945
GeneFamilyPWWP domain containing

NSD2 PWWP2B PWWP3B

3.72e-042211731147
GeneFamilyBlood group antigens|CD molecules|Proteoglycans

HSPG2 AGRN

8.54e-0471172570
GeneFamilyProprotein convertase subtilisin/kexin family

FURIN PCSK9

1.45e-0391172973
GeneFamilyWD repeat domain containing

WSB1 CFAP43 TEP1 SCAP WDR75 WDR90 MAPKBP1

1.59e-032621177362
GeneFamilyLow density lipoprotein receptors

LRP1 LRP2

3.09e-03131172634
CoexpressionNABA_CORE_MATRISOME

HSPG2 COL20A1 COL27A1 MATN3 LAMA1 SSPOP FBN1 FBN2 LTBP4 AGRN FBN3

6.51e-0727515211M5884
CoexpressionNABA_MATRISOME

PAPPA2 HSPG2 HTRA1 COL20A1 WNT3 COL27A1 MATN3 LAMA1 ADAM29 ADAMTS13 SSPOP FBN1 FBN2 WNT16 CTSE LTBP4 MUC5AC AGRN FBN3 SERPINA7

2.14e-06102615220M5889
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2C

HTRA1 COL27A1 LAMA1 MAP3K1 LRP1 UHRF1 SPRED1 TNFRSF1A SPAG17 NOTCH1 ARAP2

3.30e-0632515211M39053
CoexpressionBYSTRYKH_SCP2_QTL

MPO GGNBP2 PSMB6

3.78e-0661523M17138
CoexpressionNABA_CORE_MATRISOME

HSPG2 COL20A1 COL27A1 MATN3 LAMA1 SSPOP FBN1 FBN2 LTBP4 AGRN

4.23e-0627015210MM17057
CoexpressionNABA_MATRISOME

PAPPA2 HSPG2 HTRA1 COL20A1 WNT3 COL27A1 MATN3 LAMA1 ADAM29 ADAMTS13 SSPOP FBN1 FBN2 WNT16 CTSE LTBP4 MUC5AC AGRN SERPINA7

6.36e-06100815219MM17056
CoexpressionBYSTRYKH_SCP2_QTL

MPO GGNBP2 PSMB6

6.58e-0671523MM1140
CoexpressionRODWELL_AGING_KIDNEY_NO_BLOOD_UP

PAPPA2 DLGAP1 PLK2 PRICKLE1 COL27A1 STAB1 FBN1 SCN5A MYRF

6.74e-062241529M9893
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL3

HTRA1 NEBL DSG2 COL27A1 OBSL1 SSPOP TF MAMDC2 LRP1 LRP2 KCNMB4 TNFRSF1A SPAG17 ARAP2

6.81e-0657415214M39056
CoexpressionNABA_ECM_GLYCOPROTEINS

MATN3 LAMA1 SSPOP FBN1 FBN2 LTBP4 AGRN FBN3

1.98e-051961528M3008
CoexpressionCOLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP

HTRA1 RTN3 TF PDZD2

4.40e-05341524M11581
CoexpressionLEE_NEURAL_CREST_STEM_CELL_DN

PLK2 HTRA1 NUAK2 FBN2 NAV3 NOTCH1

8.01e-051221526M10276
CoexpressionJAK2_DN.V1_UP

DLGAP1 ZEB1 WNT3 LAMA1 SUV39H2 CCIN EGR4

9.95e-051831527M2873
CoexpressionGSE37416_CTRL_VS_0H_F_TULARENSIS_LVS_NEUTROPHIL_DN

SELL GPD1 DLGAP1 ARHGAP11A CCIN DISP3 KCNMB4

1.22e-041891527M5327
CoexpressionNABA_ECM_GLYCOPROTEINS

MATN3 LAMA1 SSPOP FBN1 FBN2 LTBP4 AGRN

1.30e-041911527MM17059
CoexpressionGSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_UP

SELL ERBB4 GC GFI1 CCIN STAB1 PDZD2

1.57e-041971527M8337
CoexpressionGSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN

ACTR8 ZFYVE16 C2CD3 FURIN TNFRSF1A NOTCH1 ARAP2

1.57e-041971527M4421
CoexpressionHALLMARK_COAGULATION

HTRA1 TF FBN1 FURIN LRP1 CTSE

1.58e-041381526M5946
CoexpressionGSE22886_NAIVE_TCELL_VS_NKCELL_DN

ACTR8 ZFYVE16 C2CD3 FURIN TNFRSF1A NOTCH1 ARAP2

1.62e-041981527M4415
CoexpressionGSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_UP

SELL PLK2 NEBL GFI1 LRP2 MAPKBP1 SERPINA7

1.67e-041991527M8401
CoexpressionGSE14769_20MIN_VS_360MIN_LPS_BMDM_DN

SELL PAPPA2 ZEB1 CCIN ITPR1 MSL2 SCAP

1.72e-042001527M3513
CoexpressionGSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_DN

SELL TEP1 MEFV ITPR1 ATAD2B AGRN NOTCH1

1.72e-042001527M8568
CoexpressionGSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_DN

UVSSA TEP1 MSL2 CEPT1 STARD9 ATAD2B TMF1

1.72e-042001527M8997
CoexpressionGSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_UP

HTRA1 DSG2 PRICKLE1 LAMA1 GPATCH2L MYPN NAV3

1.72e-042001527M5280
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP1 ZEB1 NEBL LAMA1 CFAP43 DIP2C RP1 SLC2A13 PDZD2

1.73e-081861539f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP1 ZEB1 NEBL LAMA1 CFAP43 DIP2C RP1 SLC2A13 PDZD2

1.82e-081871539c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 LAMA1 SSPOP FBN2 NAV3 DISP3 LRP2 SPAG17

2.51e-0718415382cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 LAMA1 SSPOP FBN2 NAV3 DISP3 LRP2 SPAG17

2.51e-071841538ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 LAMA1 SSPOP FBN2 NAV3 DISP3 LRP2 SPAG17

2.51e-0718415382b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

3.47e-0719215382bfac6b3956265205ca47d06888851ed68b65999
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

3.47e-071921538d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

3.75e-071941538c8b9551b93a5aed62154b487db90130604a6125c
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

3.90e-07195153812ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

SELP PLK2 ZEB1 STAB2 STAB1 PLEKHG1 NOTCH1 PDZD2

3.90e-0719515386b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

4.21e-071971538deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

4.21e-071971538a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

4.38e-071981538f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCellmild_COVID-19-HSPC|mild_COVID-19 / disease group, cell group and cell class (v2)

HSPG2 DSG2 OBSL1 FBN1 MAMDC2 ZNF418 PDZD2

1.91e-06168153790b33962adb77d8326dee403712118398b4d1315
ToppCellmild_COVID-19-HSPC|World / disease group, cell group and cell class (v2)

HSPG2 DSG2 OBSL1 FBN1 MAMDC2 ZNF418 PDZD2

2.07e-06170153785c476e0bc496445e868a88849960598d97bdea2
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPD1 WSB1 ERBB4 HTRA1 MAP3K1 SCN5A SLC2A13

2.15e-0617115375efd15300f865ebf651e0888265cbd717bc3b9d3
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DLGAP1 NEBL COL27A1 MATN3 MAMDC2 NAV3 LRP1

3.02e-06180153708ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4

3.14e-061811537a53f05c4c47465ee62e353716456bd09ab464b23
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4

3.37e-061831537709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4

3.37e-061831537dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELP STAB1 EDEM3 KCNMB4 SLC2A13 LTBP4 NOTCH1

3.62e-06185153787151ab95530e70d61328b336518df58db584acb
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZEB1 NEBL LAMA1 DIP2C RP1 SLC2A13 PDZD2

4.03e-061881537af740fa78542438fdff627ea1f74f4eee43316be
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 DSG2 PRICKLE1 WNT3 MEIOB WNT16 MAPKBP1

4.17e-0618915371cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SELP HSPG2 BCL6B PLEKHG1 FBN1 RP1 AGRN

4.17e-061891537fccadf8efbef17b7f12291b069c71060a71b04e2
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TEP1 CXXC1 ZNF891 ITPR1 STAB1 FURIN MAPKBP1

4.32e-06190153763018acb7ad80415e861643162abdc2e55968ee4
ToppCellwk_08-11-Epithelial-PNS-Schwann_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ERBB4 COL20A1 NEUROG1 WNT16 SCN5A NOTCH1 ARAP2

4.32e-0619015374a777d8aa19cadd3b61b023772df142421a89113
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4

4.47e-0619115371924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4

4.47e-06191153788f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

4.63e-0619215375890076929598e88fe9d59a4e4e858b446746ce9
ToppCellAT1_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 NEBL MATN3 ZFYVE9 MYRF AGRN ARAP2

4.63e-0619215370444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCellfacs-Thymus-Epithelium-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTR8 KCMF1 CFAP43 SUV39H2 PLEKHM3 TCTN1

4.71e-0612515366bdbbd47b699d836900bd055f2144cf960b5e7b6
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 HTRA1 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

4.79e-061931537826b8dd801298b3e0cd76232feae5a14026b8806
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

4.79e-0619315374a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 HTRA1 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

4.79e-06193153787d3a577d37fb0cb4b6313c596310de452bc3872
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

4.79e-061931537d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 HTRA1 PRICKLE1 STAB1 PLEKHG1 LTBP4 NOTCH1

4.79e-061931537d485634c564b268e344b6a2863c26f6adaec9e38
ToppCellbackground-Cholangiocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

ERBB4 NEBL PRICKLE1 NUAK2 PWWP3B MYRF AGRN

4.79e-0619315379152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|kidney / Disease (COVID-19 only), tissue and cell type

SELP HSPG2 PLK2 ZEB1 STAB1 PLEKHG1 FBN1

5.30e-061961537ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4

5.48e-061971537d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4

5.48e-061971537412091994196a06c2779b4c2cfed84be889a5f8d
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Mesothelium|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

PLK2 CHCHD10 DSG2 COL27A1 OBSL1 PWWP3B MYRF

5.85e-0619915376cfefd81e8a1a883fb4279ac4ab0b298ed2a0817
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SELP HSPG2 PLK2 ZEB1 BCL6B PLEKHG1 LTBP4

5.85e-06199153733f1669eeb701986b4dec409efdb6c06c3c41c2b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

GPD1 WSB1 PLK2 ERBB4 COL20A1 TF ZNF91

6.05e-062001537e16bde12326f0cfc4d03f9307cba0e21ea2389cb
ToppCellfacs-Thymus-Epithelium-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTR8 KCMF1 CFAP43 SUV39H2 PLEKHM3 TCTN1

6.45e-0613215366f711fe84135406a8114a898a14c5ea0dfad74f2
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HTRA1 NEBL LAMA1 RP1 SLC2A13 PDZD2

8.32e-061381536a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPD1 ERBB4 HTRA1 MAP3K1 SCN5A SLC2A13

1.61e-051551536cba6f3f7742b4d5d54ad0a0ac0dd4016e73fe658
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

HSPG2 MATN3 ZNF716 CTSE MYRF AGRN

1.93e-05160153658ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

HTRA1 FBN1 MAMDC2 NAV3 DISP3 ZNF98

2.07e-051621536e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

HTRA1 FBN1 MAMDC2 NAV3 DISP3 ZNF98

2.07e-051621536ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCellControl|World / group, cell type (main and fine annotations)

DLGAP1 ERBB4 NEBL LRP2 MUC5AC PDZD2

2.54e-051681536a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPD1 ERBB4 HTRA1 FBN1 PWWP3B SLC2A13

2.54e-051681536f3879a8e11eaf866f37c52e67021be43f0b8784a
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

NEBL ZFYVE9 RP1 MYRF ARAP2 PDZD2

3.09e-051741536548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WSB1 PLK2 ZEB1 MAMDC2 LRP1 PDZD2

3.20e-051751536cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellfacs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 STAB1 SCN5A NAV3 DHRS2 LTBP4

3.30e-051761536057d2759fdc67176c25802b57a78064d8cc93205
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 STAB1 SCN5A NAV3 DHRS2 LTBP4

3.30e-051761536b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELP PRICKLE1 FOCAD BCL6B C2CD3 ZNF418

3.41e-0517715361921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DLGAP1 NEBL MATN3 MAMDC2 NAV3 LRP1

3.74e-0518015369b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

RTN3 ARHGAP11A SCAP OR10K1 WDR90 PDZD2

3.86e-051811536c18e5a3f5d99043fa3cb33e2ac33fa98cd15d3db
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 PRICKLE1 STAB1 PLEKHG1 LTBP4

3.86e-051811536fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL LAMA1 MAP3K1 NUAK2 SLC2A13 PDZD2

3.86e-0518115369d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP1 COL20A1 COL27A1 MAMDC2 KCNMB4 DHRS2

3.98e-051821536d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCellASK454-Epithelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

NEBL MATN3 CFAP43 RP1 CTSE MYRF

3.98e-051821536ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL LAMA1 MAP3K1 NUAK2 SLC2A13 PDZD2

3.98e-051821536eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP1 COL20A1 COL27A1 MAMDC2 KCNMB4 DHRS2

3.98e-051821536e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP1 COL20A1 COL27A1 MAMDC2 KCNMB4 DHRS2

3.98e-05182153682ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLK2 STAB2 PRICKLE1 STAB1 LTBP4

3.98e-051821536b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 LAMA1 ITPR1 RP1 SLC2A13 ZNF98

4.10e-05183153631ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SELP HSPG2 ZEB1 PLEKHG1 KCNMB4 PDZD2

4.23e-0518415360f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PAPPA2 HTRA1 COL27A1 DDC FBN1 FBN2

4.36e-051851536427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 LAMA1 ITPR1 RP1 SLC2A13 ZNF98

4.36e-051851536898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP HSPG2 HTRA1 FBN1 WNT16 LTBP4

4.49e-051861536c116cc9f41971622264434ebe29d18e719b0ae19
ToppCellControl-Myeloid-DC_Mature|Myeloid / Disease state, Lineage and Cell class

ZEB1 DSG2 TTYH2 NUAK2 PLEKHG1 ARAP2

4.49e-051861536e9e58c5871b4966cd3586b611703e21af8df6360
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

NEBL RP1 MYRF AGRN FBN3 ARAP2

4.49e-05186153609d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 LAMA1 ITPR1 RP1 SLC2A13 ZNF98

4.63e-051871536b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HSPG2 FBN2 RP1 MYRF AGRN FBN3

4.63e-0518715364ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 MATN3 CTSE MYRF AGRN FBN3

4.63e-051871536f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 PLK2 ZEB1 PLEKHG1 STARD9 NAV3

4.63e-05187153635c382c0aabd46906113e5db30ea24bb8e658899
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 HTRA1 TTYH2 TF LRP2 MYRF

4.63e-05187153697e520705491c8f52a32025311a9fa7b9176979a
ToppCellfacs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 HTRA1 DSG2 WNT3 WNT16 MAPKBP1

4.63e-0518715369c1013720c248ef201d010806b6e7ad24205e8ee
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTRA1 FBN1 FBN2 MAMDC2 LRP2 LTBP4

4.63e-0518715364e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTRA1 FBN1 FBN2 MAMDC2 LRP2 LTBP4

4.63e-051871536d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTRA1 FBN1 FBN2 MAMDC2 LRP2 LTBP4

4.63e-051871536827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL LAMA1 MAP3K1 NUAK2 RP1 SLC2A13

4.63e-051871536c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZEB1 PRICKLE1 FBN1 NAV3 LRP1 LTBP4

4.77e-051881536ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 DLGAP1 PLK2 BCL6B PLEKHG1 AGRN

4.77e-0518815360026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCellfacs-Skin-Telogen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 HTRA1 DSG2 WNT3 WNT16 MAPKBP1

4.77e-0518815368cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCellfacs-Skin-nan-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WSB1 HTRA1 DSG2 PRICKLE1 WNT3 WNT16

4.91e-0518915366c71e81373cb7822de23c193a6350b6df9f567bc
ToppCell(2)_5-FU-(1)_VE-Cad+_vascular_cells|(2)_5-FU / Stress and Cell class

SELP PLK2 STAB2 STAB1 PLEKHG1 NOTCH1

4.91e-0518915360f169b17bb26a812a5b0dcd6e29a3ca8415fd197
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

NEBL COL27A1 FBN1 LRP1 PWWP3B LTBP4

4.91e-0518915360c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP1 PRICKLE1 COL27A1 ITPR1 FBN1 LRP1

4.91e-051891536c734e5693808a0333139e87bd5be2597a9252afe
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SELL ZEB1 MAP3K1 FURIN LTBP4 ARAP2

5.05e-05190153691ba66d4b56c59523485b17738e93f14bb00afa4
ToppCelltumor_Lung-Fibroblasts-Mesothelial_cells|Fibroblasts / Location, Cell class and cell subclass

DSG2 LRP2 PWWP3B CTSE MYRF AGRN

5.05e-051901536d82ab67735c1f365d4b0e02b5fa91c64cdc234da
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ERBB4 LAMA1 ITPR1 RP1 ZNF98

5.05e-051901536b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP1 PRICKLE1 COL27A1 ITPR1 FBN1 LRP1

5.05e-0519015362e592323085ba9c019d678ac2a784462ab470ed9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL LAMA1 MAP3K1 FBN2 RP1 SLC2A13

5.05e-05190153659bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 STAB2 STAB1 NAV3 PWWP3B LTBP4

5.05e-051901536f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 STAB2 STAB1 NAV3 PWWP3B LTBP4

5.05e-051901536a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP1 PRICKLE1 COL27A1 ITPR1 FBN1 LRP1

5.05e-051901536445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ERBB4 LAMA1 ITPR1 RP1 ZNF98

5.05e-0519015363dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 STAB2 STAB1 NAV3 PWWP3B LTBP4

5.05e-05190153657c136bf6d7feafb4a220877bed0cc8fdf314db2
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN2 FBN3

1.14e-0731443DOID:65 (implicated_via_orthology)
DiseaseIntermittent joint effusion

MEFV TNFRSF1A

2.37e-0521442C0149910
DiseaseColorectal Carcinoma

MPO LAMA1 ADAM29 FBN2 WNT16 ZKSCAN3 LRP1 PAN2 LRP2 DIP2C DHRS2 SPAG17 PLPPR2

4.25e-0570214413C0009402
DiseaseFamilial dilated cardiomyopathy

NEBL DSG2 MYPN SCN5A

6.35e-05441444C0340427
DiseaseS-6-hydroxywarfarin to S-warfarin ratio measurement

DLGAP1 GC BIRC6 DDX18 MYPN

7.30e-05881445EFO_0803332
Diseaseglomerulonephritis (is_marker_for)

MPO TF TNFRSF1A

1.04e-04191443DOID:2921 (is_marker_for)
Diseasecortical thickness

HSPG2 WNT3 LAMA1 CUL9 ZNF891 MAP3K1 STAB1 PLEKHG1 FBN1 FBN2 FURIN WNT16 NAV3 LRP1 FAM53B PDZD2

1.13e-04111314416EFO_0004840
DiseaseParoxysmal atrial fibrillation

HSPG2 ERBB4 NEBL WNT3 MYPN SCN5A

1.21e-041561446C0235480
Diseasefamilial atrial fibrillation

HSPG2 ERBB4 NEBL WNT3 MYPN SCN5A

1.21e-041561446C3468561
DiseasePersistent atrial fibrillation

HSPG2 ERBB4 NEBL WNT3 MYPN SCN5A

1.21e-041561446C2585653
Diseasewhite matter microstructure measurement

WNT3 ZSCAN9 ANKHD1 TF MSL2 PLEKHG1 WDR75 ZKSCAN3 LRP2

1.33e-043901449EFO_0005674
DiseaseAtrial Fibrillation

HSPG2 ERBB4 NEBL WNT3 MYPN SCN5A

1.39e-041601446C0004238
Diseasescoliosis (is_implicated_in)

FBN1 FBN2

1.41e-0441442DOID:0060249 (is_implicated_in)
DiseaseEndometrioid carcinoma ovary

PLK2 NUAK2

2.34e-0451442C0346163
Diseaseapolipoprotein A 1 measurement

PAPPA2 MARCHF8 PEX6 TF CXXC1 STAB1 MSL2 SARS1 FURIN LRP1 FAM53B MYRF PCSK9

2.76e-0484814413EFO_0004614
Diseasetransforming growth factor beta measurement

CEP85 CUL9 ADAM29

3.06e-04271443EFO_0004818
Diseasespontaneous coronary artery dissection

HTRA1 FBN1 LRP1

4.63e-04311443EFO_0010820
DiseaseHereditary Autoinflammatory Diseases

MEFV TNFRSF1A

4.89e-0471442C0751422
Diseasearrhythmogenic right ventricular cardiomyopathy (is_marker_for)

DSG2 SCN5A

4.89e-0471442DOID:0050431 (is_marker_for)
DiseaseDisproportionate short stature

HSPG2 MATN3 OBSL1 FBN1

5.58e-04771444C0878659
Diseasehydroxypalmitoyl sphingomyelin (d18:1/16:0(OH)) measurement

MYRF PCSK9

6.50e-0481442EFO_0800583
Disease1-stearoyl-2-docosahexaenoyl-GPC (18:0/22:6) measurement

PEX6 MYRF

6.50e-0481442EFO_0800392
Diseasethyroxine measurement

ERBB4 STARD9 PWWP3B SERPINA7

7.41e-04831444EFO_0005130
DiseaseDrug-Induced Liver Disease

GPD1 GC TF ITPR1 PAN2 CTSE TCTN1 NOTCH1

8.60e-044041448C0860207
DiseaseDrug-Induced Acute Liver Injury

GPD1 GC TF ITPR1 PAN2 CTSE TCTN1 NOTCH1

8.60e-044041448C3658290
DiseaseHepatitis, Toxic

GPD1 GC TF ITPR1 PAN2 CTSE TCTN1 NOTCH1

8.60e-044041448C0019193
DiseaseChemically-Induced Liver Toxicity

GPD1 GC TF ITPR1 PAN2 CTSE TCTN1 NOTCH1

8.60e-044041448C4279912
DiseaseChemical and Drug Induced Liver Injury

GPD1 GC TF ITPR1 PAN2 CTSE TCTN1 NOTCH1

8.60e-044041448C4277682
DiseaseHepatitis, Drug-Induced

GPD1 GC TF ITPR1 PAN2 CTSE TCTN1 NOTCH1

8.60e-044041448C1262760
Diseasecortical surface area measurement

WNT3 CUL9 ZNF891 MAP3K1 FOCAD PLEKHG1 FBN1 FBN2 ATAD2B NAV3 UHRF1 PLEKHM3 MPHOSPH9 SPAG17 FBN3 PDZD2

9.05e-04134514416EFO_0010736
Diseaseaortic aneurysm

FBN1 LRP1

1.04e-03101442EFO_0001666
DiseaseMarfan syndrome (implicated_via_orthology)

MATN3 FBN1

1.04e-03101442DOID:14323 (implicated_via_orthology)
Diseasediabetes mellitus (is_marker_for)

HTRA1 GC SERPINA7

1.06e-03411443DOID:9351 (is_marker_for)
Diseasevital capacity

PAPPA2 HSPG2 HTRA1 WNT3 MAP3K1 ITPR1 ATAD2B MYPN PAN2 LRP2 UHRF1 MAPKBP1 LTBP4 FBN3 PDZD2

1.08e-03123614415EFO_0004312
Diseasechronic obstructive pulmonary disease (is_marker_for)

MPO SELP TNFRSF1A MUC5AC

1.33e-03971444DOID:3083 (is_marker_for)
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

ERBB4 HTRA1 MAP3K1

1.39e-03451443DOID:3748 (is_implicated_in)
Diseaselinoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement

MYRF PDZD2

1.51e-03121442EFO_0800500
DiseaseAcute kidney injury

MPO GC TF LRP2

1.54e-031011444C2609414
DiseaseAcute Kidney Insufficiency

MPO GC TF LRP2

1.54e-031011444C1565662
DiseaseKidney Failure, Acute

MPO GC TF LRP2

1.54e-031011444C0022660
Diseasesystemic lupus erythematosus (is_marker_for)

SELL ADAMTS13 TNFRSF1A

1.58e-03471443DOID:9074 (is_marker_for)
Diseasesusceptibility to measles measurement

PAPPA2 NEBL GC

1.78e-03491443EFO_0008414
Diseaseuveitis (is_implicated_in)

GC TNFRSF1A

1.78e-03131442DOID:13141 (is_implicated_in)
Diseasedihomo-linolenoylcarnitine (C20:3n3 or 6) measurement

MARCHF8 MYRF

1.78e-03131442EFO_0800547
Diseasecongestive heart failure (biomarker_via_orthology)

SELP ERBB4 P2RX4 SCN5A

1.90e-031071444DOID:6000 (biomarker_via_orthology)
DiseaseMetabolic Bone Disorder

GC LRP2

2.07e-03141442C0005944
Diseasecoronary artery disease

ERBB4 HTRA1 ZEB1 WNT3 MAP3K1 MSL2 PLEKHG1 FBN2 FURIN LRP1 PAN2 UHRF1 RP1 PCSK9

2.17e-03119414414EFO_0001645
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN1 FBN2 NOTCH1

2.23e-03531443C4707243
Diseasefactor VIII measurement, coronary artery disease

STAB2 FURIN RP1 PCSK9

2.32e-031131444EFO_0001645, EFO_0004630
DiseaseOsteopenia

GC LRP2

2.38e-03151442C0029453
Diseaseresponse to statin, LDL cholesterol change measurement

ZNF98 PCSK9

2.38e-03151442EFO_0007804, GO_0036273
Diseasenon-high density lipoprotein cholesterol measurement

PLK2 GGNBP2 MARCHF8 PEX6 GC GFI1 DDX18 RP1 MYRF PCSK9

2.70e-0371314410EFO_0005689
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

WNT3 NOTCH1

2.71e-03161442C0334634
Diseasetriiodothyronine measurement

ERBB4 SERPINA7

2.71e-03161442EFO_0008392
Diseasevon Willebrand factor measurement, coronary artery disease

STAB2 FURIN MYRF PCSK9

2.71e-031181444EFO_0001645, EFO_0004629
Diseaseankle injury

TF WDR75 DIP2C

3.03e-03591443EFO_1002021
DiseaseMuscle hypotonia

NSD2 DDC

3.07e-03171442C0026827
Diseaseulcerative colitis (is_implicated_in)

SELL GC

3.07e-03171442DOID:8577 (is_implicated_in)
Diseasepulse pressure measurement

PAPPA2 NEBL COL27A1 SSPOP PLEKHG1 ZNF716 FBN1 FBN2 FURIN ATAD2B MYPN LRP1 UHRF1 FAM53B SLC2A13

3.39e-03139214415EFO_0005763
Diseaseoptic disc size measurement

SELP MYPN NAV3 LRP2 PDZD2

3.40e-032051445EFO_0004832
Diseaseosteochondrodysplasia (is_implicated_in)

HSPG2 MATN3

3.83e-03191442DOID:2256 (is_implicated_in)
Diseaseesterified cholesterol measurement, high density lipoprotein cholesterol measurement

OBSL1 MYRF

3.83e-03191442EFO_0004612, EFO_0008589
DiseaseCardiomyopathies

NEBL DSG2 MYPN SCN5A

3.84e-031301444C0878544
Diseaseretinal vasculature measurement

HSPG2 ERBB4 TTYH2 ITPR1 PLEKHG1 MYPN NAV3 PDZD2

3.98e-035171448EFO_0010554
Diseaselow density lipoprotein cholesterol measurement, physical activity

DDX18 RP1 PCSK9

4.16e-03661443EFO_0003940, EFO_0004611
DiseaseMultiple Epiphyseal Dysplasia

HSPG2 MATN3

4.24e-03201442C0026760
DiseaseIgA glomerulonephritis (is_marker_for)

SELL TNFRSF1A

4.24e-03201442DOID:2986 (is_marker_for)
Diseasebreast carcinoma

PLK2 ERBB4 NEBL WNT3 ADAM29 MAP3K1 ITPR1 FBN1 FBN2 WDR75 ZKSCAN3 SPAG17

4.33e-03101914412EFO_0000305

Protein segments in the cluster

PeptideGeneStartEntry
LSNCTLTDGSTCAFG

ADAM29

426

Q9UKF5
GATAEIFDDSCCNGT

ERBB4

1096

Q15303
EASTGASCSCAVVPE

BEST2

426

Q8NFU1
ACCPSSLSAAVGTED

CFAP43

436

Q8NDM7
EDCIVDSCKFGTSVS

ATP13A5

561

Q4VNC0
LSAEGISCITCSGLF

DISP3

776

Q9P2K9
CTDGTDRISCFGSGS

BIRC6

381

Q9NR09
EDLAGCSTACASLLT

BIRC6

1461

Q9NR09
DCFDTSTGDVVQCIT

CCIN

446

Q13939
ESVCATYGSGLSSTC

ACTR8

266

Q9H981
VTCSFGSTCARSADG

AGRN

251

O00468
GSTCARSADGLTASC

AGRN

256

O00468
GCSQDDECVSLRSSS

DLGAP1

501

O14490
NADSECLSFVGCSTS

ARAP2

211

Q8WZ64
ATLGTTTCCSFDNLL

DDC

241

P20711
SLDFTGINCVDTDEC

FBN3

2116

Q75N90
DGTLSLCVSGSCRTF

ADAMTS13

516

Q76LX8
CSKESGLAETESCGQ

RBAKDN

11

A6NC62
DATTVCKSDASCTAG

P2RX4

121

Q99571
SDTCFLDTDGQATCD

HSPG2

826

P98160
FCCRSGSAADTQAVA

PSMB6

76

P28072
CAFEESTCGFDSVLA

MAMDC2

26

Q7Z304
SLNASIGCCSFIEGE

DSG2

806

Q14126
SCSLTGSVAEETLGC

MEIOB

391

Q8N635
SGCVSFTADSLRCAA

OBSL1

1606

O75147
CSSGDSVIGQLFSCE

PAN2

646

Q504Q3
EDESGFTCCAFSARE

DCAF1

1091

Q9Y4B6
DCTESSCFNGGTCVD

NOTCH1

986

P46531
STEDACGCEATLAFQ

MATN3

441

O15232
ETCISDLDCASSSGS

NEUROG1

6

Q92886
DRASASPDSCEGSVC

GFI1

66

Q99684
ETDFIENSSCKACGS

GGNBP2

406

Q9H3C7
FSDVCRVESGENCSS

ITPR1

2501

Q14643
ASSQFLCSSGRCVAE

LRP1

2906

Q07954
DGRTCADVDECSTTF

LRP1

2976

Q07954
EVVSFCDSGDKCSSE

ATAD2B

1291

Q9ULI0
ARTGTETDTCTACAG

EDEM3

216

Q9BZQ6
FCSEGCQAIVDTGTS

CTSE

271

P14091
TFSSLSCLSAGTEDC

FAM53B

306

Q14153
EDIIGASSDCSTCFV

PCSK9

366

Q8NBP7
TTGDACVSTSCELAS

PDZD2

1186

O15018
ARASFVTGVNCETSC

MPO

271

P05164
CSSLCAESSGAVETK

PEX6

496

Q13608
STSLGLSSDCIASYC

NAV3

1971

Q8IVL0
DACLAAGCSVIASNS

NSD2

796

O96028
CSVSSGYGTFCISEL

MPHOSPH9

41

Q99550
SDTNSSCCTEPEDTG

MARCHF8

271

Q5T0T0
SQCAFSCSEGTNLTG

SELL

221

P14151
FTSACTFICSEGTEL

SELL

281

P14151
LCASSSGDDGCAFAE

GCN1

1066

Q92616
EDCGITATGCQSLAS

NLRP5

931

P59047
GASSFTCSNGRCISE

LRP2

2701

P98164
CTAGFETNVFDRTSC

LRP2

3991

P98164
TCVRDSCSFPEAVSG

MEFV

326

O15553
CRSLSEGDITCSVGF

MUC5AC

721

P98088
ALNSCGASGDLADSC

EGR4

156

Q05215
FEDISTSRCESCGAV

PLEKHM3

696

Q6ZWE6
FCNADSGTLLCTDVA

DDX18

471

Q9NVP1
TVATDLCSTGIDICS

MSL2

241

Q9HCI7
LCSTGIDICSFSEDI

MSL2

246

Q9HCI7
IGESTIVSGACCRFS

PLPPR2

106

Q96GM1
CQRSSTSDDDSGCAL

PRICKLE1

16

Q96MT3
ASGSLCGACTEDGTF

PAPPA2

876

Q9BXP8
VSSADTGLCSEACLF

FAM189B

521

P81408
SVSVSDALGSCIIDC

ERVK-7

101

P63130
GCDSLSTVFVVLGTC

CEPT1

156

Q9Y6K0
DSDDTDLQIFCVSCG

CXXC1

476

Q9P0U4
VCASSEPVCGSDANT

HTRA1

111

Q92743
CEAVAGCSSGLDSLV

BCL6B

306

Q8N143
IPSCCVSFATADESS

C2CD3

1661

Q4AC94
SRDGETCPAFVSACS

COL20A1

1051

Q9P218
GSFICECSSESTLDP

FBN1

826

P35555
DCSTTQSDLSLCEGF

CHCHD10

111

Q8WYQ3
TSSQACVVCEEGFSL

FURIN

591

P09958
CGILTDAVFAACTST

GPR148

121

Q8TDV2
GTSCSDIAEDFCSSS

CEP85

61

Q6P2H3
LGSCGVTVALTSDAC

DIP2C

431

Q9Y2E4
LGCSSDTIEVSCNFT

COL27A1

1711

Q8IZC6
TFLESCGVADLITTC

GPD1

251

P21695
SSCSFSCEEGFALVG

SELP

286

P16109
DSTFCITSSGLLCEF

MAPKBP1

246

O60336
QSGICTNTDGSFECI

LTBP4

931

Q8N2S1
CETSSVCSSSDTGLF

GPATCH2L

221

Q9NWQ4
FECTFTCGADCRGTS

KCNMB4

66

Q86W47
DLCASCYESGATTTR

KCMF1

31

Q9P0J7
CETGNLETSCGSSTA

KRTAP26-1

71

Q6PEX3
AGGVACTSTDVLSCI

CUL9

1916

Q8IWT3
CSEGFTGDGFTCSDV

FBN2

1436

P35556
GESEDCAGIVSFLCS

DHRS2

246

Q13268
PEGRADCASESACSS

PWWP2B

411

Q6NUJ5
LTCTTSCVISSGLDD

SCAP

1166

Q12770
LSCVCTSAFSAGIIE

FOCAD

1191

Q5VW36
GISSLDGGCSASEAC

RP1

1231

P56715
AAACACGFTVSLVTT

OR10K1

146

Q8NGX5
SISGDVVEACCSVLS

MAP3K1

626

Q13233
ESCDSSKFTCLSGLS

MCM9

176

Q9NXL9
ESLFDNRLCTCGTSD

SLC2A13

606

Q96QE2
ALGTKSCSSSCADSF

RTN3

36

O95197
SGAFRELVSCSNCTD

SARS1

386

P49591
CDGALSSCIESASKD

ARHGAP11A

876

Q6P4F7
SGEIESCLTEVESCF

UVSSA

186

Q2YD98
AGSANASAGSLEECC

SSPOP

126

A2VEC9
GSCSRECEVSFSASN

PWWP3B

311

Q5H9M0
SECFCFGVSDVCSSL

LAMA1

501

P25391
SDVLLCGNSSDAGTC

SCN5A

321

Q14524
SSFQSDLDFCSDCGS

POLR1H

11

Q9P1U0
TGESFCDCAGQSEAS

SPSB3

66

Q6PJ21
AQSCCGASSDSTESG

STARD9

1891

Q9P2P6
GDSCFSLTDCQEVTA

NUAK2

601

Q9H093
EDSSCCATFGDGTTI

SPAG17

1506

Q6Q759
ETALTLACCGGFSEV

ANKHD1

506

Q8IWZ3
SCCSSDAFERIDSFS

TMF1

316

P82094
CSECGRSFAENSSLI

ZNF586

236

Q9NXT0
ECSDCGKSFAENSSL

ZNF586

346

Q9NXT0
FSCEECGNVFTTSSD

ZNF718

311

Q3SXZ3
CDSFVCAEVGIGNSS

ZNF700

126

Q9H0M5
VCSLSFSDSGALLCG

WDR90

456

Q96KV7
EECGRTFNCSSTVKA

ZNF735

356

P0CB33
ECTECGRTFSDISNF

ZNF691

256

Q5VV52
ECSECGRSFSKSSAL

ZSCAN20

876

P17040
VTDCSGNFCLFRSET

TF

631

P02787
SGCDGISACLFLSDD

TEP1

1716

Q99973
ATNCCFSEDGSLLAV

WDR75

501

Q8IWA0
AADGSAAVATSDFCV

TTYH2

261

Q9BSA4
SDSEGDFSDPCSCDT

SPRED1

381

Q7Z699
ISLVNEATFGCSCTD

SUV39H2

181

Q9H5I1
ECNECGKSFSSSFSL

ZNF558

321

Q96NG5
ECSECGRAFSQSSSL

ZNF514

261

Q96K75
ACGDCGRCFSESSTL

ZNF672

256

Q499Z4
SFGACCSTQTEIVET

SERPINA7

81

P05543
DCSSVDFSVFSACSV

TCTN1

96

Q2MV58
CEECGKAFTTFSSLT

ZNF728

426

P0DKX0
SLGECCDVEDSTTCF

GC

371

P02774
EECGKSFNCSSTLTR

ZNF716

216

A6NP11
AVTRSCAEGTSTICG

WNT3

126

P56703
ETSCSFDSSICSGEG

WAPL

1006

Q7Z5K2
VQDSAGASTCACAAG

STAB1

1431

Q9NY15
DTFTTFDASGECGSC

STAB2

1891

Q8WWQ8
ECSCDTTLQNGGSAS

WNT16

146

Q9UBV4
SFEGGVNDSTCLLCD

ZEB1

521

P37275
CEECGKAFSQSSTLT

ZNF91

996

Q05481
SDTDSGCCLGQSESD

UHRF1

91

Q96T88
CSECGKSFAETFSLT

ZNF418

621

Q8TF45
CEECGRAFSQSSTLT

ZNF98

296

A6NK75
DDCGKTFSQSCSLLE

ZKSCAN3

401

Q9BRR0
STFLGLEADFVCCDS

PLEKHG1

766

Q9ULL1
CDECGKSFTQSSGLI

ZSCAN9

256

O15535
GTLGSCSSSSECLED

PLK2

451

Q9NYY3
LSNGLCCAFSTDGSV

WSB1

351

Q9Y6I7
CCAFSTDGSVLAAGT

WSB1

356

Q9Y6I7
ECSECGKLFSFNSSL

ZNF419

316

Q96HQ0
GQDTDCRECESGSFT

TNFRSF1A

76

P19438
DCSECGKAFSRSSSL

ZNF71

131

Q9NQZ8
CEECGKGFTLFSTLT

ZNF680

436

Q8NEM1
ECSDCGKVFSGVSSL

ZNF891

461

A8MT65
CEECGKAFTAFSTLT

ZNF506

371

Q5JVG8
GTCISESEECDFSTV

ZFYVE9

451

O95405
ECSECGKSFAESSSL

ZNF814

801

B7Z6K7
ESSDCCEGFINTFSS

ZFYVE16

491

Q7Z3T8
CDSFVCEVGLGNSSS

ZNF439

121

Q8NDP4
FAEDSGCFTCTASNK

MYPN

506

Q86TC9
DLVDTDGSFAVSTSC

MYRF

796

Q9Y2G1
SFSCCSEVTRPSDEG

NEBL

906

O76041