Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone deacetylase activity, NAD-dependent	SIRT3 SIRT1	6.88e-05	5	53	2	GO:0017136
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF668 KLF1 EGR1 ZSCAN4 ZNF746 ZNF324 ZNF580 ZNF324B ZNF785 ZNF786 SIRT1 ZNF169 ZNF304	8.52e-05	1459	53	13	GO:0000977
GeneOntologyMolecularFunction	NAD-dependent protein lysine deacetylase activity	SIRT3 SIRT1	1.44e-04	7	53	2	GO:0034979
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF668 KLF1 EGR1 ZSCAN4 ZNF746 ZNF324 ZNF580 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	2.63e-04	1412	53	12	GO:0000981
GeneOntologyMolecularFunction	complement component C1q complex binding	C4A C4B	3.07e-04	10	53	2	GO:0001849
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF668 KLF1 EGR1 ZSCAN4 ZNF746 ZNF324 ZNF580 ZNF324B ZNF786 SIRT1 ZNF304	3.54e-04	1244	53	11	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF668 KLF1 EGR1 ZSCAN4 ZNF746 ZNF324 ZNF580 ZNF324B ZNF786 SIRT1 ZNF304	4.26e-04	1271	53	11	GO:0000987
GeneOntologyMolecularFunction	NAD+ binding	SIRT3 SIRT1	1.27e-03	20	53	2	GO:0070403
GeneOntologyMolecularFunction	promoter-specific chromatin binding	EGR1 SIRT1 ZNF304	1.40e-03	83	53	3	GO:1990841
GeneOntologyMolecularFunction	histone deacetylase activity	SIRT3 SIRT1	1.84e-03	24	53	2	GO:0004407
GeneOntologyMolecularFunction	opsonin binding	C4A C4B	1.99e-03	25	53	2	GO:0001846
GeneOntologyMolecularFunction	protein lysine deacetylase activity	SIRT3 SIRT1	1.99e-03	25	53	2	GO:0033558
GeneOntologyMolecularFunction	NAD+-protein poly-ADP-ribosyltransferase activity	SIRT3 SIRT1	2.50e-03	28	53	2	GO:0003950
GeneOntologyMolecularFunction	NAD+-protein ADP-ribosyltransferase activity	SIRT3 SIRT1	2.87e-03	30	53	2	GO:1990404
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	RNF19A CHFR PELI1 TRIM39 HECTD1	3.01e-03	372	53	5	GO:0061630
GeneOntologyMolecularFunction	complement binding	C4A C4B	3.26e-03	32	53	2	GO:0001848
GeneOntologyBiologicalProcess	glial cell-derived neurotrophic factor receptor signaling pathway	NRTN RET GFRA4	7.13e-06	15	53	3	GO:0035860
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	TGFB1I1 COL4A1 MYOF COMP EGR1 NRTN LRP2 DSG4 RET GFRA4 SIRT1 ADAMTSL2	3.66e-05	1186	53	12	GO:0007167
GeneOntologyBiologicalProcess	negative regulation of peptidyl-lysine acetylation	SIRT3 SIRT1	6.45e-05	5	53	2	GO:2000757
GeneOntologyCellularComponent	symbiont cell surface	C4A C4B	1.68e-04	8	52	2	GO:0106139
GeneOntologyCellularComponent	other organism part	C4A C4B	2.16e-04	9	52	2	GO:0044217
MousePheno	abnormal blood vessel physiology	TGFB1I1 COL4A1 MYOF COMP EGR1 C4A C4B KCTD1	1.89e-05	394	42	8	MP:0000249
MousePheno	decreased vascular permeability	MYOF C4A C4B	1.99e-05	18	42	3	MP:0003071
MousePheno	abnormal vasculature physiology	TGFB1I1 COL4A1 MYOF COMP EGR1 C4A C4B KCTD1	2.26e-05	404	42	8	MP:0031170
MousePheno	abnormal parasympathetic postganglionic fiber morphology	NRTN RET	2.64e-05	3	42	2	MP:0008313
MousePheno	abnormal kidney physiology	COL4A1 NMNAT2 C4A C4B KCTD1 RET SIRT1	1.08e-04	372	42	7	MP:0002136
MousePheno	abnormal eye size	COL4A1 NMNAT2 EGR1 MARK4 LRP2 HECTD1 SIRT1	1.13e-04	375	42	7	MP:0002697
Domain	ZINC_FINGER_C2H2_2	ZBTB44 ZNF668 ZNF775 KLF1 EGR1 ZSCAN4 ZNF746 HELZ2 ZNF324 ZNF580 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	2.33e-09	775	53	15	PS50157
Domain	ZINC_FINGER_C2H2_1	ZBTB44 ZNF668 ZNF775 KLF1 EGR1 ZSCAN4 ZNF746 HELZ2 ZNF324 ZNF580 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	2.42e-09	777	53	15	PS00028
Domain	Znf_C2H2-like	ZBTB44 ZNF668 ZNF775 KLF1 EGR1 ZSCAN4 ZNF746 HELZ2 ZNF324 ZNF580 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	3.36e-09	796	53	15	IPR015880
Domain	-	ZBTB44 ZNF668 ZNF775 KLF1 EGR1 ZSCAN4 ZNF746 ZNF324 ZNF580 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	3.99e-09	679	53	14	3.30.160.60
Domain	ZnF_C2H2	ZBTB44 ZNF668 ZNF775 KLF1 EGR1 ZSCAN4 ZNF746 HELZ2 ZNF324 ZNF580 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	4.11e-09	808	53	15	SM00355
Domain	zf-C2H2	ZBTB44 ZNF668 ZNF775 KLF1 EGR1 ZSCAN4 ZNF746 ZNF324 ZNF580 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	5.17e-09	693	53	14	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZBTB44 ZNF668 ZNF775 KLF1 EGR1 ZSCAN4 ZNF746 ZNF324 ZNF580 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	5.27e-09	694	53	14	IPR013087
Domain	Znf_C2H2	ZBTB44 ZNF668 ZNF775 KLF1 EGR1 ZSCAN4 ZNF746 ZNF324 ZNF580 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	3.43e-08	805	53	14	IPR007087
Domain	-	SIRT3 SIRT1	4.72e-05	4	53	2	3.30.1600.10
Domain	Sirtuin_cat_small_dom	SIRT3 SIRT1	4.72e-05	4	53	2	IPR026591
Domain	KRAB	ZNF746 ZNF324 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	6.47e-05	358	53	7	PS50805
Domain	KRAB	ZNF746 ZNF324 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	6.47e-05	358	53	7	PF01352
Domain	KRAB	ZNF746 ZNF324 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	7.83e-05	369	53	7	SM00349
Domain	Anaphylatoxin_comp_syst	C4A C4B	7.86e-05	5	53	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	7.86e-05	5	53	2	IPR001840
Domain	KRAB	ZNF746 ZNF324 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	7.96e-05	370	53	7	IPR001909
Domain	ANATO	C4A C4B	1.64e-04	7	53	2	SM00104
Domain	ANATO	C4A C4B	1.64e-04	7	53	2	PF01821
Domain	SIR2	SIRT3 SIRT1	1.64e-04	7	53	2	PF02146
Domain	ANAPHYLATOXIN_2	C4A C4B	1.64e-04	7	53	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	1.64e-04	7	53	2	PS01177
Domain	Ssirtuin_cat_dom	SIRT3 SIRT1	1.64e-04	7	53	2	IPR026590
Domain	Sirtuin	SIRT3 SIRT1	1.64e-04	7	53	2	IPR003000
Domain	SIRTUIN	SIRT3 SIRT1	1.64e-04	7	53	2	PS50305
Domain	Anaphylatoxin/fibulin	C4A C4B	1.64e-04	7	53	2	IPR000020
Domain	Thiol-ester_cl	C4A C4B	2.19e-04	8	53	2	PF10569
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	2.19e-04	8	53	2	IPR019565
Domain	MacrogloblnA2_CS	C4A C4B	2.19e-04	8	53	2	IPR019742
Domain	zf-C2H2_6	ZBTB44 ZNF668 ZNF746 ZNF324 ZNF324B ZNF169	2.54e-04	314	53	6	PF13912
Domain	A2M_N	C4A C4B	3.50e-04	10	53	2	PF01835
Domain	A2M_N	C4A C4B	3.50e-04	10	53	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	3.50e-04	10	53	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	3.50e-04	10	53	2	PS00477
Domain	A2M	C4A C4B	3.50e-04	10	53	2	PF00207
Domain	A2M_N_2	C4A C4B	3.50e-04	10	53	2	IPR011625
Domain	A2M_comp	C4A C4B	3.50e-04	10	53	2	IPR011626
Domain	A2M_N_2	C4A C4B	3.50e-04	10	53	2	PF07703
Domain	A2M_recep	C4A C4B	3.50e-04	10	53	2	PF07677
Domain	A2M_comp	C4A C4B	3.50e-04	10	53	2	PF07678
Domain	Macroglobln_a2	C4A C4B	3.50e-04	10	53	2	IPR001599
Domain	-	SIRT3 SIRT1	4.27e-04	11	53	2	3.40.50.1220
Domain	DHS-like_NAD/FAD-binding_dom	SIRT3 SIRT1	5.12e-04	12	53	2	IPR029035
Domain	TIL_dom	FCGBP LRP2	7.03e-04	14	53	2	IPR002919
Domain	C345C	C4A C4B	1.05e-03	17	53	2	SM00643
Domain	Znf_RING_CS	RNF224 MID2 CHFR TRIM39	1.17e-03	163	53	4	IPR017907
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	1.17e-03	18	53	2	IPR008930
Domain	NTR	C4A C4B	1.31e-03	19	53	2	PF01759
Domain	Netrin_module_non-TIMP	C4A C4B	1.31e-03	19	53	2	IPR018933
Domain	ZF_RING_1	RNF224 MID2 RNF19A CHFR TRIM39	1.38e-03	291	53	5	PS00518
Domain	ZF_RING_2	RNF224 MID2 RNF19A CHFR TRIM39	1.53e-03	298	53	5	PS50089
Domain	RING	RNF224 MID2 RNF19A CHFR TRIM39	1.70e-03	305	53	5	SM00184
Domain	NTR	C4A C4B	1.92e-03	23	53	2	PS50189
Domain	Netrin_domain	C4A C4B	1.92e-03	23	53	2	IPR001134
Domain	Znf_RING	RNF224 MID2 RNF19A CHFR TRIM39	2.27e-03	326	53	5	IPR001841
Domain	TIMP-like_OB-fold	C4A C4B	2.46e-03	26	53	2	IPR008993
Domain	Znf-RING_LisH	RNF224 MID2	4.18e-03	34	53	2	IPR027370
Domain	zf-RING_UBOX	RNF224 MID2	4.18e-03	34	53	2	PF13445
Domain	AAA+_ATPase	ABCG4 HELZ2 NVL	7.94e-03	144	53	3	IPR003593
Domain	AAA	ABCG4 HELZ2 NVL	7.94e-03	144	53	3	SM00382
Domain	-	RNF224 MID2 RNF19A CHFR TRIM39	8.74e-03	449	53	5	3.30.40.10
Domain	Znf_RING/FYVE/PHD	RNF224 MID2 RNF19A CHFR TRIM39	9.56e-03	459	53	5	IPR013083
Pathway	WP_NAD_METABOLISM	NMNAT2 SIRT3 SIRT1	1.65e-05	16	45	3	M39541
Pathway	WP_NAD_METABOLISM_IN_ONCOGENEINDUCED_SENESCENCE_AND_MITOCHONDRIAL_DYSFUNCTIONASSOCIATED_SENESCENCE	NMNAT2 SIRT3 SIRT1	5.15e-05	23	45	3	M40059
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF668 PMS2 ZNF775 ZNF746 ZNF324 KCTD1 RET ZNF324B ZNF785 ZNF786 SIRT3 SIRT1 ZNF169 ZNF304	6.64e-05	1387	45	14	M734
Pathway	REACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION	SIRT3 SIRT1	1.48e-04	6	45	2	MM15660
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	2.07e-04	7	45	2	MM14685
Pathway	REACTOME_RET_SIGNALING	NRTN RET GFRA4	2.37e-04	38	45	3	MM15493
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	2.76e-04	8	45	2	M27031
Pathway	KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	2.76e-04	8	45	2	M47872
Pathway	REACTOME_RET_SIGNALING	NRTN RET GFRA4	2.77e-04	40	45	3	M27746
Pathway	REACTOME_NCAM1_INTERACTIONS	COL4A1 NRTN GFRA4	3.20e-04	42	45	3	M7169
Pathway	REACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION	SIRT3 SIRT1	4.41e-04	10	45	2	M27945
Pathway	WP_NAD_METABOLISM_SIRTUINS_AND_AGING	SIRT3 SIRT1	5.38e-04	11	45	2	M39439
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	5.38e-04	11	45	2	MM1430
Pathway	KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	5.38e-04	11	45	2	M47874
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	ZNF775 ZNF746 ZNF324 KCTD1 ZNF324B ZNF786 SIRT3 SIRT1 ZNF169	6.08e-04	768	45	9	MM14851
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	6.44e-04	12	45	2	MM1368
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	7.60e-04	13	45	2	M4732
Pathway	WP_SIDS_SUSCEPTIBILITY_PATHWAYS	C4A C4B RET	8.72e-04	59	45	3	MM15838
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	COL4A1 NRTN DSG4 RET GFRA4 SIRT1 SPINK5	9.76e-04	502	45	7	MM14537
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	1.02e-03	15	45	2	M7146
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	COL4A1 NRTN GFRA4	1.06e-03	63	45	3	M11187
Pathway	WP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY	C4A C4B	1.31e-03	17	45	2	MM15944
Pathway	BIOCARTA_COMP_PATHWAY	C4A C4B	1.31e-03	17	45	2	MM1369
Pathway	WP_SUDDEN_INFANT_DEATH_SYNDROME_SIDS_SUSCEPTIBILITY_PATHWAYS	EGR1 C4A C4B RET	1.62e-03	159	45	4	M39373
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL4A1 COMP ICAM5	1.82e-03	76	45	3	MM14867
Pathway	BIOCARTA_COMP_PATHWAY	C4A C4B	1.83e-03	20	45	2	M917
Pathway	WP_COMPLEMENT_ACTIVATION	C4A C4B	2.21e-03	22	45	2	M39502
Pathway	WP_NAD_BIOSYNTHETIC_PATHWAYS	SIRT3 SIRT1	2.21e-03	22	45	2	M39704
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION	SIRT3 SIRT1	2.21e-03	22	45	2	MM15656
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL4A1 COMP ICAM5	2.50e-03	85	45	3	M16441
Pathway	PID_HDAC_CLASSIII_PATHWAY	SIRT3 SIRT1	3.08e-03	26	45	2	M32
Pubmed	A rapid and dynamic regulation of GDNF-family ligands and receptors correlate with the developmental dependency of cutaneous sensory innervation.	NRTN RET GFRA4	2.95e-07	9	54	3	10331972
Pubmed	Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.	MYOF MYH6 C4A C4B SPINK5	3.31e-07	92	54	5	37343697
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	RNF224 NMNAT2 RNF19A CHFR HECTD1	3.89e-07	95	54	5	29643511
Pubmed	Distinct roles for GFRalpha1 and GFRalpha2 signalling in different cranial parasympathetic ganglia in vivo.	NRTN RET GFRA4	4.21e-07	10	54	3	11069590
Pubmed	Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems.	NRTN RET GFRA4	1.00e-06	13	54	3	22855506
Pubmed	Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH.	SIRT3 SIRT1	2.37e-06	2	54	2	29958828
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	2.37e-06	2	54	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	2.37e-06	2	54	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	2.37e-06	2	54	2	15998580
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	2.37e-06	2	54	2	7373044
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	2.37e-06	2	54	2	19062096
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	2.37e-06	2	54	2	3696167
Pubmed	SIRT1-SIRT3 Axis Regulates Cellular Response to Oxidative Stress and Etoposide.	SIRT3 SIRT1	2.37e-06	2	54	2	27925196
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	2.37e-06	2	54	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	2.37e-06	2	54	2	16098595
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	2.37e-06	2	54	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	2.37e-06	2	54	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	2.37e-06	2	54	2	17645767
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	2.37e-06	2	54	2	15787745
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	2.37e-06	2	54	2	12207352
Pubmed	Imbalance of Lysine Acetylation Contributes to the Pathogenesis of Parkinson's Disease.	SIRT3 SIRT1	2.37e-06	2	54	2	33003340
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	2.37e-06	2	54	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	2.37e-06	2	54	2	6559257
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	2.37e-06	2	54	2	27758680
Pubmed	SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside.	SIRT3 SIRT1	2.37e-06	2	54	2	33690226
Pubmed	Alterations of SIRT1/SIRT3 subcellular distribution in aging undermine cardiometabolic homeostasis during ischemia and reperfusion.	SIRT3 SIRT1	2.37e-06	2	54	2	37537789
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	2.37e-06	2	54	2	22387014
Pubmed	Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1.	EGR1 PTGES	2.37e-06	2	54	2	12034740
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	2.37e-06	2	54	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	2.37e-06	2	54	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	2.37e-06	2	54	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	2.37e-06	2	54	2	26800705
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	2.37e-06	2	54	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	2.37e-06	2	54	2	23918728
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	2.37e-06	2	54	2	15390104
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	2.37e-06	2	54	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	2.37e-06	2	54	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	2.37e-06	2	54	2	4216347
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	2.37e-06	2	54	2	1699796
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	2.37e-06	2	54	2	6950384
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	2.37e-06	2	54	2	2997024
Pubmed	Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH.	SIRT3 SIRT1	2.37e-06	2	54	2	27040510
Pubmed	Dietary fatty acids as nutritional modulators of sirtuins: a systematic review.	SIRT3 SIRT1	2.37e-06	2	54	2	32403131
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	2.37e-06	2	54	2	8660986
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	2.37e-06	2	54	2	3624865
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	2.37e-06	2	54	2	8428773
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	2.37e-06	2	54	2	21857912
Pubmed	Cerebellar Predominant Increase in mRNA Expression Levels of Sirt1 and Sirt3 Isoforms in a Transgenic Mouse Model of Huntington's Disease.	SIRT3 SIRT1	2.37e-06	2	54	2	32524313
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	2.37e-06	2	54	2	24638111
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	2.37e-06	2	54	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	2.37e-06	2	54	2	4514997
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	2.37e-06	2	54	2	21345967
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	2.37e-06	2	54	2	5919331
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	2.37e-06	2	54	2	3167981
Pubmed	An autoregulatory loop reverts the mechanosensitive Sirt1 induction by EGR1 in skeletal muscle cells.	EGR1 SIRT1	2.37e-06	2	54	2	22820707
Pubmed	Sirtuins-mediators of maternal obesity-induced complications in offspring?	SIRT3 SIRT1	2.37e-06	2	54	2	26667041
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	2.37e-06	2	54	2	7545960
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	2.37e-06	2	54	2	30041577
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	2.37e-06	2	54	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	2.37e-06	2	54	2	2302180
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	2.37e-06	2	54	2	3862104
Pubmed	The BS variant of C4 protects against age-related loss of white matter microstructural integrity.	C4A C4B	2.37e-06	2	54	2	34358307
Pubmed	Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.	C4A C4B	2.37e-06	2	54	2	18360261
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	2.37e-06	2	54	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	2.37e-06	2	54	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	2.37e-06	2	54	2	29080553
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	2.37e-06	2	54	2	26814963
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	2.37e-06	2	54	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	2.37e-06	2	54	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	2.37e-06	2	54	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	2.37e-06	2	54	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	2.37e-06	2	54	2	6149581
Pubmed	Obesity and aging diminish sirtuin 1 (SIRT1)-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3.	SIRT3 SIRT1	2.37e-06	2	54	2	28808064
Pubmed	Activation of AMPK/Sirt3 pathway by phloretin reduces mitochondrial ROS in vascular endothelium by increasing the activity of MnSOD via deacetylation.	SIRT3 SIRT1	2.37e-06	2	54	2	32195489
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	2.37e-06	2	54	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	2.37e-06	2	54	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	2.37e-06	2	54	2	2387317
Pubmed	Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.	C4A C4B	2.37e-06	2	54	2	8132550
Pubmed	Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.	C4A C4B	2.37e-06	2	54	2	2395880
Pubmed	Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.	C4A C4B	2.37e-06	2	54	2	26814708
Pubmed	Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3-dependent mechanism in male mice.	SIRT3 SIRT1	2.37e-06	2	54	2	30801823
Pubmed	15d-PGJ₂ decreases PGE₂ synthesis in HBx-positive liver cells by interfering EGR1 binding to mPGES-1 promoter.	EGR1 PTGES	2.37e-06	2	54	2	25108236
Pubmed	cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).	C4A C4B	2.37e-06	2	54	2	6192448
Pubmed	Complete primary structure of human C4a anaphylatoxin.	C4A C4B	2.37e-06	2	54	2	6167582
Pubmed	The modulation of SIRT1 and SIRT3 by natural compounds as a therapeutic target in doxorubicin-induced cardiotoxicity: A review.	SIRT3 SIRT1	2.37e-06	2	54	2	34747550
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	2.37e-06	2	54	2	16908004
Pubmed	Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.	C4A C4B	2.37e-06	2	54	2	1438267
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	2.37e-06	2	54	2	7365238
Pubmed	SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2.	SIRT3 SIRT1	2.37e-06	2	54	2	21701047
Pubmed	Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.	C4A C4B	2.37e-06	2	54	2	19150565
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	2.37e-06	2	54	2	7391573
Pubmed	Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.	C4A C4B	2.37e-06	2	54	2	17506029
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	2.37e-06	2	54	2	17971360
Pubmed	Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.	C4A C4B	2.37e-06	2	54	2	23715124
Pubmed	Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.	C4A C4B	2.37e-06	2	54	2	3464002
Pubmed	Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.	C4A C4B	2.37e-06	2	54	2	2993295
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	2.37e-06	2	54	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	2.37e-06	2	54	2	17971229
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	2.37e-06	2	54	2	6881182
Pubmed	4'-Bromo-resveratrol, a dual Sirtuin-1 and Sirtuin-3 inhibitor, inhibits melanoma cell growth through mitochondrial metabolic reprogramming.	SIRT3 SIRT1	2.37e-06	2	54	2	31292999
Interaction	ZNF324B interactions	ZNF746 HELZ2 ZNF324 TRIM39 ZNF324B	4.00e-06	89	54	5	int:ZNF324B
Interaction	ZNF324 interactions	ZNF324 ZNF324B ZNF785 ZNF169	6.91e-06	46	54	4	int:ZNF324
Interaction	UBE2D2 interactions	RNF224 MID2 RNF19A CHFR PELI1 TRIM39 HECTD1	2.14e-05	318	54	7	int:UBE2D2
Interaction	ZNF460 interactions	ZNF324 TRIM39 ZNF324B ZNF785 SIRT1	3.38e-05	138	54	5	int:ZNF460
Interaction	NRTN interactions	NRTN RET	4.21e-05	4	54	2	int:NRTN
Interaction	ZNF764 interactions	MID2 HELZ2 ZNF324 TRIM39	1.13e-04	93	54	4	int:ZNF764
Interaction	ZNF785 interactions	MID2 ZNF324 ZNF785 SIRT1	1.22e-04	95	54	4	int:ZNF785
Interaction	UBE2E2 interactions	MID2 RNF19A CHFR TRIM39	1.27e-04	96	54	4	int:UBE2E2
Interaction	NOTCH2 interactions	ZBTB44 ZNF668 ZNF775 ZNF746 ZNF324 RET ZNF324B	1.29e-04	423	54	7	int:NOTCH2
Cytoband	7q36.1	ZNF775 ZNF746 ZNF786	9.40e-05	74	54	3	7q36.1
Cytoband	19q13.43	ZSCAN4 ZNF324 ZNF324B	1.52e-04	87	54	3	19q13.43
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	FCGBP ZSCAN4 MARK4 ZNF324 ZNF580 ZNF324B ZNF304	4.78e-04	1192	54	7	chr19q13
Cytoband	Ensembl 112 genes in cytogenetic band chr7q36	ZNF775 ZNF746 ZNF786	8.88e-04	159	54	3	chr7q36
Cytoband	16p11.2	TGFB1I1 ZNF668 ZNF785	1.50e-03	191	54	3	16p11.2
Cytoband	14q12	MYH6 HECTD1	1.94e-03	55	54	2	14q12
Cytoband	6p21.3	C4A C4B TRIM39	3.22e-03	250	54	3	6p21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr16p11	TGFB1I1 ZNF668 ZNF785	4.34e-03	278	54	3	chr16p11
Cytoband	Ensembl 112 genes in cytogenetic band chr9q34	RNF224 PTGES ADAMTSL2	6.68e-03	325	54	3	chr9q34
Cytoband	9q34.3	RNF224 PTGES	6.99e-03	106	54	2	9q34.3
Cytoband	Ensembl 112 genes in cytogenetic band chr20p13	DEFB126 GFRA4	9.30e-03	123	54	2	chr20p13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZBTB44 ZNF668 ZNF775 KLF1 EGR1 ZSCAN4 ZNF746 ZNF324 ZNF580 ZNF324B ZNF785 ZNF786 ZNF169 ZNF304	1.14e-09	718	45	14	28
GeneFamily	Sirtuins	SIRT3 SIRT1	1.26e-04	7	45	2	938
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	2.16e-04	9	45	2	1234
GeneFamily	Ring finger proteins	RNF224 MID2 RNF19A CHFR TRIM39	5.83e-04	275	45	5	58
GeneFamily	Complement system\|Sushi domain containing	C4A C4B	3.62e-03	36	45	2	492
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	C4A C4B	3.82e-03	37	45	2	454
Drug	salvianolic acid	SIRT3 SIRT1	5.52e-06	2	54	2	ctd:C568740
Drug	Meclozine dihydrochloride [1104-22-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A	ZBTB44 EGR1 PTGES ZNF324 RET ZNF324B	5.95e-06	191	54	6	5607_DN
Drug	Iocetamic acid [16034-77-8]; Down 200; 6.6uM; MCF7; HT_HG-U133A	TGFB1I1 MID2 MARK4 ZNF324 ZNF580 SPINK5	7.32e-06	198	54	6	3361_DN
Drug	O-Ln	NRTN RET GFRA4 SIRT1	9.47e-06	56	54	4	CID000656979
Drug	2-aminothiophenol	C4A C4B	1.65e-05	3	54	2	ctd:C005464
Drug	telomestatin	PMS2 EGR1 RET	3.15e-05	26	54	3	CID000443590
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	MYOF EGR1 ZNF324 PELI1 RET	7.68e-05	185	54	5	5585_DN
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	MYOF RNF19A MARK4 ZNF580 SIRT3	7.88e-05	186	54	5	1664_UP
Drug	PF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A	NMNAT2 EGR1 NRTN MARK4 LRP2	8.93e-05	191	54	5	5917_UP
Drug	Metergoline [17692-51-2]; Down 200; 10uM; MCF7; HT_HG-U133A	ZNF668 PTGES ZNF324 ZNF324B SIRT3	9.38e-05	193	54	5	3221_DN
Drug	Iopanoic acid [96-83-3]; Down 200; 7uM; MCF7; HT_HG-U133A	MYOF GPR27 MARK4 LRP2 ZNF324B	9.61e-05	194	54	5	5448_DN
Drug	Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; HL60; HT_HG-U133A	GPR27 KLF1 EGR1 LRP2 SIRT3	9.61e-05	194	54	5	2485_DN
Drug	0173570-0000 [211245-44-2]; Down 200; 10uM; MCF7; HT_HG-U133A	ZBTB44 MID2 MARK4 ZNF324 ZNF324B	9.85e-05	195	54	5	4712_DN
Drug	Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; MCF7; HT_HG-U133A	GPR27 MARK4 PELI1 ZNF324B SIRT3	9.85e-05	195	54	5	2852_DN
Drug	Demecarium bromide [56-94-0]; Up 200; 5.6uM; MCF7; HT_HG-U133A	MYOF EGR1 PTGES ZNF324 PELI1	1.01e-04	196	54	5	6269_UP
Drug	Medrysone [2668-66-8]; Up 200; 11.6uM; PC3; HT_HG-U133A	ABCG4 KLF1 EGR1 ICAM5 PTGES	1.01e-04	196	54	5	3705_UP
Drug	Pregnenolone [145-13-1]; Down 200; 12.6uM; MCF7; HT_HG-U133A	TGFB1I1 MYOF NRTN ZNF324 ZNF580	1.01e-04	196	54	5	4802_DN
Drug	Sertaconazole nitrate [99592-39-9]; Down 200; 8uM; MCF7; HT_HG-U133A	RNF19A MARK4 PTGES ZNF324 SIRT3	1.03e-04	197	54	5	3550_DN
Drug	Salbutamol [18559-94-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A	TGFB1I1 RNF19A MARK4 PTGES ZNF324	1.03e-04	197	54	5	2306_DN
Drug	Thioridazine hydrochloride [130-61-0]; Down 200; 9.8uM; MCF7; HT_HG-U133A	ZNF668 MARK4 LRP2 ZNF324B SIRT3	1.03e-04	197	54	5	1486_DN
Drug	Ritodrine hydrochloride [23239-51-2]; Down 200; 12.4uM; MCF7; HT_HG-U133A	MID2 RNF19A ZNF324 PELI1 SPINK5	1.03e-04	197	54	5	2635_DN
Drug	Arcaine sulfate [14923-17-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A	TGFB1I1 EGR1 LRP2 ZNF324B ZNF304	1.03e-04	197	54	5	4974_DN
Drug	Tolfenamic acid [13710-19-5]; Up 200; 15.2uM; HL60; HG-U133A	ABCG4 ZBTB44 MYOF GPR27 ZNF324B	1.06e-04	198	54	5	1437_UP
Drug	LY294002; Up 200; 10uM; MCF7; HT_HG-U133A	EGR1 NRTN SIRT3 SPINK5 ZNF304	1.06e-04	198	54	5	5937_UP
Drug	phenformin hydrochloride; Down 200; 10uM; MCF7; HG-U133A	TGFB1I1 NMNAT2 PMS2 EGR1 CHFR	1.06e-04	198	54	5	21_DN
Drug	Caffeic acid [3331-39-5]; Up 200; 22.2uM; MCF7; HT_HG-U133A	MYOF PTGES SIRT3 SPINK5 ZNF304	1.06e-04	198	54	5	5352_UP
Drug	Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; MCF7; HT_HG-U133A	MYOF RNF19A SENP2 SIRT3 SPINK5	1.08e-04	199	54	5	4831_DN
Drug	Acetopromazine maleate salt [3598-37-6]; Down 200; 9uM; MCF7; HT_HG-U133A	ZBTB44 EGR1 PTGES ZNF324 ZNF324B	1.08e-04	199	54	5	2769_DN
Drug	Nizatidine [76963-41-2]; Down 200; 12uM; PC3; HT_HG-U133A	MYOF NRTN ZNF324 SENP2 SIRT3	1.08e-04	199	54	5	6305_DN
Drug	Procaine hydrochloride [51-05-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A	EGR1 MARK4 PTGES LRP2 ZNF324B	1.11e-04	200	54	5	1674_UP
Drug	Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A	MYOF RNF19A SIRT3 SPINK5 ZNF304	1.11e-04	200	54	5	5513_UP
Disease	Hydronephrosis	EGR1 PTGES	2.92e-05	5	51	2	C0020295
Disease	Aganglionic megacolon	NRTN RET	4.37e-05	6	51	2	cv:C0019569
Disease	Autoimmune Diseases	EGR1 C4B SIRT1	5.32e-05	42	51	3	C0004364
Disease	Hirschsprung's disease (is_implicated_in)	NRTN RET	1.59e-04	11	51	2	DOID:10487 (is_implicated_in)
Disease	Hydrops Fetalis	NMNAT2 KLF1	4.92e-04	19	51	2	C0020305
Disease	Adenocarcinoma of large intestine	PMS2 MARK4 RET	6.21e-04	96	51	3	C1319315
Disease	ocular sarcoidosis	PMS2 LRP2 KCTD1	1.07e-03	116	51	3	EFO_0010723
Disease	Complement deficiency disease	C4A C4B	1.49e-03	33	51	2	C0272242
Disease	Heart Failure, Diastolic	COL4A1 MYH6	1.49e-03	33	51	2	C1135196

Protein segments in the cluster

Peptide	Gene	Start	Entry
TCLEERCPFREPQSI	ABCG4	591	Q9H172
ALCVSFPQPCRAAER	RNPEP	121	Q9H4A4
ARVQQPDCREPFLSC	C4B	721	P0C0L5
CFPRVRCINTSPGFR	COMP	136	P49747
IRPFISRCAVCEAPA	COL4A1	1541	P02462
CVIFFDEVDALCPRR	NVL	676	O15381
RERVRAQPCCRPTAY	NRTN	156	Q99748
PEQDVCSAFRPFVRD	SPINK5	156	Q9NQ38
NDYCPNIFPERRTIC	DSG4	491	Q86SJ6
RPYACPVESCDRRFS	EGR1	336	P18146
RDCFRAQFPCCQSPR	GPR27	346	Q9NS67
REPETQPVCFFRCAR	ICAM5	91	Q9UMF0
FSRPCECLVVRVAPD	KCTD1	136	Q719H9
RYQLCRVQECPPDGR	ADAMTSL2	96	Q86TH1
SEFLCVNDRPPDRRC	LRP2	2951	P98164
TCCFQPMPDRRAERE	CHFR	486	Q96EP1
VDRCFETCPPRTFLP	HECTD1	41	Q9ULT8
QRPFRCQLCPRAFSR	KLF1	336	Q13351
PACAERRRQTFVPSC	GFRA4	91	Q9GZZ7
RELSERACCFQAVPP	LINC00473	91	A8K010
REWRRPDFCPFQCPA	FCGBP	3526	Q9Y6R7
TAAARCRCRQPQPFL	MARK4	681	Q96L34
CCCRFRIPEPVRQAD	ENDOV	226	Q8N8Q3
RDCCVPADRRANYPV	DEFB126	56	Q9BYW3
CCLTDDRQAFRPPTR	HELZ2	621	Q9BYK8
ARVQQPDCREPFLSC	C4A	721	P0C0L4
RFACRIICERNPPFT	PELI1	136	Q96FA3
TIFRFCDRSVPPARA	SENP2	11	Q9HC62
ERDFPCPVCRKTSRY	TRIM39	61	Q9HCM9
RTFRDVVRFEVAPCP	PIK3R6	696	Q5UE93
TFCQACVRRLDTPAP	RNF224	46	P0DH78
DIFNQVVPRCPRCPA	SIRT1	386	Q96EB6
CTVCQRPFPGEDIRA	SIRT3	256	Q9NTG7
PQYCRSDPDVERCLR	PTGES	56	O14684
AQTRPFDIRTECFVP	MYH6	26	P13533
FVCTQCGRAFRERPA	ZNF324	481	O75467
QRPFRCEECGRAFAE	ZNF668	361	Q96K58
RVNISCPECTERFNP	RNF19A	171	Q9NV58
DRPFQCPTCGVRFTR	ZBTB44	396	Q8NCP5
RPFCCPECARRFSQK	ZNF775	161	Q96BV0
DRQFFFINRRPCDPA	PMS2	286	P54278
CFPETRPSFRIRENR	RET	166	P07949
QRRHRNERPFVCPEC	ZSCAN4	331	Q8NAM6
RPFQCPECNRSFRLK	ZNF786	591	Q8N393
ERFSPRCGFCNQPIR	TGFB1I1	281	O43294
AEVRPFRCLPCGNVF	ZNF304	246	Q9HCX3
RPFPCTECEKRFTER	ZNF746	536	Q6NUN9
RIACQFCEQDPPRDA	MID2	136	Q9UJV3
TCPLCPRRFQDAAEL	ZNF580	151	Q9UK33
ERPFLCLECGRSFRQ	ZNF169	371	Q14929
RRIHSDSRPFPCVEC	ZNF785	331	A8K8V0
FVCTQCGRAFRERPA	ZNF324B	481	Q6AW86
QCTIERLDRFRCDPY	MYOF	1391	Q9NZM1
SRICCVRPPVERFTF	NMNAT2	161	Q9BZQ4