Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Domain-

HELT BHLHA9 HES6 MESP2 MESP1

2.21e-051095854.10.280.10
DomainHLH

HELT BHLHA9 HES6 MESP2 MESP1

2.41e-05111585PF00010
DomainHLH

HELT BHLHA9 HES6 MESP2 MESP1

2.99e-05116585SM00353
DomainBHLH

HELT BHLHA9 HES6 MESP2 MESP1

3.11e-05117585PS50888
DomainbHLH_dom

HELT BHLHA9 HES6 MESP2 MESP1

3.24e-05118585IPR011598
DomainHairy_orange

HELT HES6

6.13e-0412582PF07527
DomainOrange_dom

HELT HES6

6.13e-0412582IPR003650
DomainORANGE

HELT HES6

7.23e-0413582PS51054
Pubmed

Repurposing of the enhancer-promoter communication underlies the compensation of Mesp2 by Mesp1.

MESP2 MESP1

3.23e-06263235025872
Pubmed

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.

MEF2B KMT2D

3.23e-06263221796119
Pubmed

Transcriptional regulation of Mesp1 and Mesp2 genes: differential usage of enhancers during development.

MESP2 MESP1

3.23e-06263211578861
Pubmed

The roles of Mesp family proteins: functional diversity and redundancy in differentiation of pluripotent stem cells and mammalian mesodermal development.

MESP2 MESP1

3.23e-06263226088191
Pubmed

Identification of presomitic mesoderm (PSM)-specific Mesp1 enhancer and generation of a PSM-specific Mesp1/Mesp2-null mouse using BAC-based rescue technology.

MESP2 MESP1

3.23e-06263218328678
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KMT2D SPG7 MEGF8 PCNX3 DGKQ HES6 RELB LTBP3 ZNF579 SIPA1L2 KIFC2

4.30e-061105631135748872
Pubmed

Cooperative Mesp activity is required for normal somitogenesis along the anterior-posterior axis.

MESP2 MESP1

9.68e-06363216996494
Pubmed

Spatial and temporal deletion reveals a latent effect of Megf8 on the left-right patterning and heart development.

MEGF8 MESP1

1.93e-05463232203821
Pubmed

Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.

BHLHA9 HES6 MESP2 MESP1

3.11e-059863418557763
Pubmed

Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2.

MESP2 MESP1

3.22e-05563218849530
Pubmed

Differential contributions of Mesp1 and Mesp2 to the epithelialization and rostro-caudal patterning of somites.

MESP2 MESP1

3.22e-05563215677726
Pubmed

Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1.

IRF7 RELB

4.82e-05663222065573
Pubmed

MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons.

MEGF8 MESP1

6.74e-05763224052814
Pubmed

A genome-wide survey on basic helix-loop-helix transcription factors in rat and mouse.

HELT HES6

6.74e-05763219306043
Pubmed

Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes.

KMT2D RELB

6.74e-05763219219072
Pubmed

I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection.

IRF7 RELB

8.98e-05863223422957
Pubmed

The repression of Notch signaling occurs via the destabilization of mastermind-like 1 by Mesp2 and is essential for somitogenesis.

MESP2 MESP1

1.15e-04963221098559
Pubmed

Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation.

MESP2 MESP1

1.76e-04116329242490
Pubmed

Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening.

BHLHA9 MESP2

2.11e-041263214516699
Pubmed

MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube.

MESP2 MESP1

2.11e-041263210393122
Pubmed

Appropriate suppression of Notch signaling by Mesp factors is essential for stripe pattern formation leading to segment boundary formation.

MESP2 MESP1

2.11e-041263217306789
Pubmed

Inducible interleukin 32 (IL-32) exerts extensive antiviral function via selective stimulation of interferon λ1 (IFN-λ1).

IRF7 RELB

2.11e-041263223729669
Pubmed

A census of human transcription factors: function, expression and evolution.

KMT2D HELT BHLHA9 TBX10 IRF7 RELB MESP2 MESP1

2.28e-0490863819274049
Pubmed

The mouse rib-vertebrae mutation disrupts anterior-posterior somite patterning and genetically interacts with a Delta1 null allele.

MESP2 MESP1

2.49e-041363210906448
Pubmed

The SCF-FBXW7 E3 ubiquitin ligase triggers degradation of histone 3 lysine 4 methyltransferase complex component WDR5 to prevent mitotic slippage.

KMT2D PRR36

2.49e-041363236395886
Pubmed

Formal proof of the requirement of MESP1 and MESP2 in mesoderm specification and their transcriptional control via specific enhancers in mice.

MESP2 MESP1

2.49e-041363234679163
Pubmed

The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes.

MESP2 MESP1

2.90e-041463210837126
Pubmed

Genetic rescue of segmentation defect in MesP2-deficient mice by MesP1 gene replacement.

MESP2 MESP1

2.90e-04146329739106
Pubmed

Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation.

MESP2 MESP1

3.34e-041563232561646
Pubmed

Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse.

MESP2 MESP1

3.34e-041563210330372
Pubmed

KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation.

KMT2D MESP1

4.32e-041763226932671
Pubmed

The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis.

MESP2 MESP1

5.41e-041963211562355
Pubmed

The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation.

MESP2 MESP1

5.41e-041963221822279
Pubmed

Supt20 is required for development of the axial skeleton.

MESP2 MESP1

6.63e-042163227894818
Pubmed

Histone Lysine Methyltransferase SETD2 Regulates Coronary Vascular Development in Embryonic Mouse Hearts.

HES6 MESP1

7.29e-042263233898448
Pubmed

MesP1 and MesP2 are essential for the development of cardiac mesoderm.

MESP2 MESP1

8.69e-042463210887078
Pubmed

Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.

ACAN TBX10

9.43e-042563229475039
Pubmed

Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development.

ACAN MESP2

1.02e-032663219590010
Pubmed

ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.

MESP2 MESP1

1.36e-033063218462699
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

ASB16-AS1 PCNX3 FAAP20 PEX13 ZNF579 EDEM1 SIPA1L2 NCKAP5L

1.53e-03121563815146197
Pubmed

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.

DGKQ SIPA1L2

1.64e-033363225064009
Cytoband15q26.1

ACAN MESP2 MESP1

5.81e-055463315q26.1
Cytoband4q35.1

HELT FAM149A

1.13e-03366324q35.1
Cytoband12q13.12

KMT2D NCKAP5L

1.26e-033863212q13.12
Cytoband16q24.3

CTU2 SPG7

2.35e-035263216q24.3
CytobandEnsembl 112 genes in cytogenetic band chr15q26

ACAN MESP2 MESP1

2.90e-03206633chr15q26
Cytoband11q13.1

PCNX3 LTBP3

3.43e-036363211q13.1
CytobandEnsembl 112 genes in cytogenetic band chr11q13

PCNX3 TBX10 LTBP3 ARHGEF17

3.55e-03454634chr11q13
Cytoband19p13.11

MEF2B GMIP

4.57e-037363219p13.11
Cytoband1p36.33

FAAP20 TMEM88B

5.08e-03776321p36.33
GeneFamilyBasic helix-loop-helix proteins

HELT BHLHA9 HES6 MESP2 MESP1

4.22e-06110405420
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCARF1 CD1E EBI3 RELB GGT5

5.20e-061776353a150dcaefa342d49968b42c7cdb1fbb633adcd0
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SCARF1 CD1E EBI3 RELB GGT5

5.20e-06177635c9e5820ff0bc7ad1adcfb2651713fdfc58bced56
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|normal_Lung / Location, Cell class and cell subclass

CD1E MEF2B EBI3 CFP RELB

6.62e-061866350987c9a39503eb6c75a2bf4db98b2b2fd46956fb
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Activated_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

CD1E EBI3 ALPK3 CFP RELB

8.12e-06194635219056d4ad256cda73208b8c570bbf689219df83
ToppCellBAL-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CD1E EBI3 CFP RELB GGT5

8.33e-061956356ba23e19801305e071b0e4aaf1ee6f53f3b027d3
ToppCellBAL-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD1E EBI3 CFP RELB GGT5

8.33e-0619563566e5fd9f3208a06d617c5e994822bf57dceae7e2
ToppCellBAL-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CD1E EBI3 CFP RELB GGT5

8.33e-061956357209babdff96c93cd52cfe5d5cfd7e3c0274d8dd
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD1E EBI3 CFP RELB GGT5

8.33e-061956352f2e29089a8cb748d2c1329c5c8465165b25bc8b
ToppCellBAL-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD1E EBI3 CFP RELB GGT5

8.33e-061956359e5cf33b5dd455efa464a63d7116786c0786aefd
ToppCellMild_COVID-19-Myeloid-cDC|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

CD1E EBI3 CFP RELB GGT5

8.33e-0619563524149bb6933135b1a0a5c7f505914942b3782c3a
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD1E EBI3 CFP RELB GGT5

8.33e-06195635c9469e2d31beb30ebb64b3f0a5239e23119fbaa5
ToppCellBronchial-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD1E EBI3 RUSC1-AS1 CFP RELB

8.75e-0619763568d8546dfe7dffd017756a11d3333061f576d0ef
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MEF2B LDLRAD2 GPR173 C1QTNF4

4.26e-051376343f4746fb6fc36c90a8cd25725531a1503422cfbf
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GUCY2D TBX10 PRSS33 IRF7

6.07e-0515063457f21ad380fd1350a2c25d75ad8c3b763ded53ec
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCARF1 RASIP1 SCNN1D RELB

6.89e-0515563459035d792c26d870a8b097939e97fa47859ba68c
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EBI3 ALPK3 SSPOP FAM149A

7.98e-0516163476c993a4533362db2250c88b3ee3ede55362d54e
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHFPL4 METRN EBI3 AMER3

8.37e-051636348dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHFPL4 METRN EBI3 AMER3

8.37e-05163634fd243ca223079033be480a24817a399f281fa4d4
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|metastatic_Brain / Location, Cell class and cell subclass

ASB16-AS1 RASIP1 LINC01465 IRF7

8.57e-0516463406db4cc064f0765c481ce880207823872c27bfa9
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD1E EBI3 CFP RELB

8.98e-0516663475d719617c61409860f298ce91cbe3a0aafa0553
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

ASB16-AS1 RASIP1 LINC01465 IRF7

9.41e-051686344bf3f85aac4b335efa93d22c9ce7b153cb5ce152
ToppCellMild_COVID-19-Myeloid-MoAM5|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

DUSP8 SCNN1D RUSC1-AS1 CFP

9.85e-05170634b2daf46ab5a49590ede8f75e4240bfe6e9d8b764
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PRR36 TBX10 HES6 AMER3

9.85e-0517063498d13dbd76a826e47d55553f9d11f71c043b573e
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKRN3 LHFPL4 CACNA2D2 TMEM88B

1.01e-0417163482de2885c8ce4fb7776da6a0207b3355c0910121
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKRN3 LHFPL4 CACNA2D2 TMEM88B

1.01e-0417163409e653973962fb884878089d281f0947f7a285f6
ToppCell367C-Myeloid-Dendritic-cDC_activated|367C / Donor, Lineage, Cell class and subclass (all cells)

CD1E EBI3 CFP RELB

1.05e-0417363494f99f7e7813d6e53e0bedf97087400b1bf00129
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAN HES6 C1QTNF4 IL17D

1.05e-041736342b448acd5e584f24567204c31b8d74715e92f32a
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAN HES6 C1QTNF4 IL17D

1.05e-041736345086edc29c5a6137ca09877929a1317f9739c801
ToppCellwk_20-22-Hematologic-Myeloid-CXCL9+_Mac|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

EBI3 CFP IRF7 GGT5

1.10e-0417563448f5bdbfc1ba40c3fb6411f12a69e61da2138296
ToppCellwk_15-18-Hematologic-Myeloid-aDC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CD1E EBI3 CFP RELB

1.10e-04175634c31178d7a5a19d7afd336c9ec0e5c493655a6aa4
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 RASIP1 GUCY2D IRF7

1.10e-041756347be76d39e1a4f4ac709672cd2d409a2523a083ce
ToppCellwk_15-18-Hematologic-Myeloid-aDC_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CD1E EBI3 CFP RELB

1.15e-04177634ccf5dc54780d6039a4d062dee88440c011ddc0a3
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Activated_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

CD1E EBI3 CFP RELB

1.15e-04177634370aee11a6dc2c6f4366a13c3171f37bc5b32d65
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRR36 CACNA2D2 HES6 DCDC2B

1.18e-041786349099b47e0756d6a1b7ba1c6aa7b47c5425f649e0
ToppCellwk_20-22-Hematologic-Myeloid-aDC_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CD1E EBI3 CFP RELB

1.18e-04178634fd2bdb4796e86c8cff2d25f0c730ffea21db8787
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR173 AMER3 GRIN2C ZNF579

1.20e-04179634878b15ea62e3405682a538f79f58d74b9cd3f398
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 RASIP1 CFP GGT5

1.23e-041806347d4cb0ab9f96088cbc5db3096d884a1e5ce4cb5d
ToppCellwk_20-22-Hematologic-Myeloid-aDC_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CD1E EBI3 CFP IRF7

1.25e-041816348f7e5c310f4cdc4b2fb54fea950d01e56bd298e1
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD1E IRF7 RELB FAM149A

1.31e-04183634bd78e5c2670e67b4363078e3ca5a5b7081d24b7e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD1E IRF7 RELB FAM149A

1.31e-04183634d1bf3abf42eb9d7facf775becf1338d1faadd647
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-maDC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CD1E EBI3 CFP RELB

1.31e-04183634e01dacb08a9c36cf09c0b6764ce032a7232d4cdc
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD1E EBI3 CFP RELB

1.31e-041836349ca4954faaba50466c35121d6765895e955178aa
ToppCellwk_15-18-Hematologic-Myeloid-CXCL9+_Mac|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EBI3 CFP IRF7 RELB

1.31e-0418363499a36e9c74346b619b3b87d8d6bbf9b4b797c821
ToppCellStriatum-Macroglia|Striatum / BrainAtlas - Mouse McCarroll V32

MKRN3 METRN HES6 ZNF579

1.34e-041846349ed6a7c7171823b72561db9a6c1de47e82edc4c9
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP3 NCKAP5L PRRC2A TMEM88B

1.39e-04186634bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

CD1E MEF2B EBI3 RELB

1.39e-0418663400ad1239b952119b3fd2e6af8f034cba3488f9c1
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ACAN GPR173 IL17D GGT5

1.42e-04187634f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ACAN GPR173 IL17D GGT5

1.42e-0418763402e7246ef5ad41773d14426254e139b156d45c1d
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ACAN GPR173 IL17D GGT5

1.42e-0418763408c73d125e0638c9e9878165bba2442c266c8a48
ToppCell390C-Myeloid-Dendritic-cDC_activated|390C / Donor, Lineage, Cell class and subclass (all cells)

CD1E EBI3 CFP RELB

1.42e-0418763460c2576f31a60f819deb9ec500d1f714b469df4e
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CD1E ZC3H12A EBI3 CFP

1.48e-0418963431c8bc506ad69f2ed5676bd7e5319bad1075c8d8
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP3 NCKAP5L PRRC2A TMEM88B

1.48e-04189634965e0e388251e7318f8b463816dc96ccb4658677
ToppCell(3)_DC_activated|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CD1E EBI3 CFP RELB

1.48e-04189634e977838793fc0eb1499e81018e33e4ccb4a5f0c5
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LHFPL4 HELT HES6 AMER3

1.51e-04190634b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SCARF1 RASIP1 CFP GGT5

1.57e-041926347dbe3117a0f58ff2e838963d49f788a59a4351d7
ToppCellMild-Myeloid-mDC|Mild / Condition, Lineage, Cell class and cell subclass

CD1E EBI3 CFP RELB

1.57e-04192634da3952bd5c96242c15eb76678d0608ae2926a16e
ToppCellMild-Myeloid-mDC-|Mild / Condition, Lineage, Cell class and cell subclass

CD1E EBI3 CFP RELB

1.57e-041926348520b3fdf4508ac66f7918da613abc928ab5832a
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 RASIP1 CFP GGT5

1.60e-041936342661ad9107ed9231e4afea4442a79051139a31df
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SCARF1 CD1E EBI3 RELB

1.60e-04193634704378de39e1b6f108ab5b0ecbd594d414ec8ae4
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCARF1 CD1E EBI3 RELB

1.64e-0419463436f8ae4f2b3bf802f6ff0e9fc79e7f170f96ae8b
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

LHFPL4 GPR173 AMER3 ARHGEF17

1.64e-04194634b6488bc3a8905e926ad298332963e1bbaf010046
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

LHFPL4 GPR173 AMER3 ARHGEF17

1.64e-041946341e1f4139ad584f493d75a9b7f1568eca4653c5a2
ToppCelltumor_Lung-Myeloid_cells-Activated_DCs|tumor_Lung / Location, Cell class and cell subclass

CD1E EBI3 CFP RELB

1.64e-04194634a85d958aff84f2296c330a7dcd442bd2344738df
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

SCARF1 CD1E EBI3 CFP

1.64e-04194634e2d9186a7e8d1a4a71d7bd6dba7fc955d55479e6
ToppCell390C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CD1E EBI3 CFP RELB

1.67e-04195634ecf7d9856a5b507ec17c325c9a772dc5a184bc8e
ToppCell10x5'-GI_small-bowel-Myeloid_Dendritic|GI_small-bowel / Manually curated celltypes from each tissue

SCARF1 CD1E EBI3 CFP

1.70e-04196634571fade4d65427d277b7d37446b289ea5ebb8635
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD1E EBI3 CFP RELB

1.74e-041976342a140c61e81aa18de2c9c1c443e314d6f09cdc18
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD1E EBI3 CFP RELB

1.74e-04197634fa3fe934bd5fd8c6520a9c46357f9e441c794aba
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD1E EBI3 CFP RELB

1.74e-0419763432eb4437cc608b8369e376446d639497ecfdd17a
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC2-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD1E EBI3 CFP RELB

1.77e-04198634c58e2d3a21fcca9f1accccc5303ca4222b6c8432
ToppCellCaecum-(6)_Macrophage-(61)_LYVE1_Macrophage|Caecum / shred on region, Cell_type, and subtype

EBI3 CFP SIPA1L2 SSPOP

1.77e-04198634e684c3934c163aef4d284b69435832d2c9614f2a
ToppCellCaecum-Macrophage-LYVE1_Macrophage|Caecum / Region, Cell class and subclass

EBI3 CFP SIPA1L2 SSPOP

1.77e-04198634a92c0cacb775aca6bbb302bd9e22c081a112a44d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC2|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD1E EBI3 CFP RELB

1.77e-04198634f4ff9520598ebc52b3a1f31eee766957983e16b4
ToppCellNon-neuronal-Postmitotic-Endothelial|World / Primary Cells by Cluster

SCARF1 RASIP1 ALPK3 GGT5

1.80e-04199634b9763ac9857a60db6f1f104fe1e9ea2266cf931b
ToppCellmLN-Dendritic_cell-cDC2|mLN / Region, Cell class and subclass

SCARF1 CD1E EBI3 CFP

1.80e-04199634cb17bccb47d04f7793709f9a4376fcc8ce95430c
ToppCellNon-neuronal-Postmitotic-Endothelial-Endothelial-24|World / Primary Cells by Cluster

SCARF1 RASIP1 ALPK3 GGT5

1.80e-041996340b4edf3e359749827ef978a77b5267ddde732d71
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

GPR173 C1QTNF4 IL17D GGT5

1.80e-0419963407b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD1E CFP RELB GMIP

1.80e-041996346dc446a5d183b01bdf227e45bd88d0b3d8b1c56a
ToppCellNon-neuronal-Postmitotic-Endothelial-Endothelial|World / Primary Cells by Cluster

SCARF1 RASIP1 ALPK3 GGT5

1.80e-041996349e01eee126247a0696c71b019f855a8a41a0ede3
ToppCelldistal-2-Hematologic-Myeloid_Dendritic_Type_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD1E EBI3 CFP EDEM1

1.80e-0419963486ee039189c75e66b97453c20a34d7fb5a31e51d
ToppCellmLN-(5)_Dendritic_cell-(50)_cDC2|mLN / shred on region, Cell_type, and subtype

SCARF1 CD1E EBI3 CFP

1.80e-041996348d1b18596a0965427abefe0be744c74e4c11d5d3
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CCL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EBI3 HES6 RELB GRIN2C

1.80e-0419963451be0e3a91d1f25454b56d55ef6342ef8e8df4e8
ToppCellParenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD1E EBI3 CFP RELB

1.80e-04199634f4ab29f99ce45a3044d2e9f356dc24d3c5e7121f
ToppCellBronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD1E EBI3 CFP RELB

1.84e-04200634a4c41509ca936e137230a6ae548c90f18a566d12
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal|GW10 / Sample Type, Dataset, Time_group, and Cell type.

DGKQ RELB KIFC2 GGT5

1.84e-042006345c638c80661017c85f9390f1b398ac7728c8f001
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal-BMP_responsible_cell|GW10 / Sample Type, Dataset, Time_group, and Cell type.

DGKQ RELB KIFC2 GGT5

1.84e-04200634604a88633d4162337e394155c7346dbdef8b9f5a
ToppCellControl_saline-Hematopoietic_Myeloid-Dendritic_cells|Control_saline / Treatment groups by lineage, cell group, cell type

HES6 CFP IRF7 RELB

1.84e-042006341559844b3116d41a69081e4ee89e64744a760181
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CACNA2D2 MESP2 GGT5

2.22e-04836331ab68323518adc7fd0a459b41fad12d60f97eb5c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR-CR_Lhx5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CACNA2D2 MESP2 GGT5

2.22e-048363375b27d91a4473286f4b40027e96ac5246f5abe5b
DiseaseMitral valve prolapse, response to surgery

ALPK3 LTBP3

2.65e-0412602EFO_0009951, HP_0001634
DiseaseLeft ventricular mass to end-diastolic volume ratio

FAAP20 ALPK3

1.18e-0325602EFO_0010556
DiseaseJT interval

FAAP20 ALPK3 LTBP3 ZNF579

1.64e-03248604EFO_0007885
Diseasesexual dimorphism measurement

SPG7 METRN CACNA2D2 ACAN ALPK3 TBX10 RELB LTBP3

1.73e-031106608EFO_0021796

Protein segments in the cluster

PeptideGeneStartEntry
GPPGVLGCFRGPWRP

AMER3

646

Q8N944
SRPGPARTARPWPGC

CACNA2D2

11

Q9NY47
GTPSPDGPWCFSPEG

DUSP8

516

Q13202
RRCPGASSAGPPPWP

BHLHA9

206

Q7RTU4
GTWAPAPPGVSKPRC

ALPK3

126

Q96L96
PAACWALGPTPGPGS

C1QTNF4

11

Q9BXJ3
AWLGGGSPRPGSPAC

DGKQ

11

P52824
GSPGRPAAHSPWACG

ASB16-AS1

31

Q495Z4
RTGGSGPARPPWLPA

RASIP1

491

Q5U651
RPGATPPGPGWAFSC

RASIP1

506

Q5U651
PPGPGWAFSCRLCGR

RASIP1

511

Q5U651
PWGCPLGRLVSPAPG

RELB

106

Q01201
GPPRAPGRSGWPAGG

HES6

151

Q96HZ4
YRGCRPAPGSAAGWP

KIRREL3-AS3

151

Q8N7Y1
LREWGSGSPPCVPGP

ARHGEF17

341

Q96PE2
GSWSPADCRGPSPVP

LDLRAD2

206

Q5SZI1
SGAGPFPWPPGAARS

HELT

171

A6NFD8
CSPATPWRPPGQGPG

NCKAP5L

206

Q9HCH0
GRPWGPSRGPPQAQG

NCKAP5L

271

Q9HCH0
PRPAGGPSGGRPWFL

FAAP20

16

Q6NZ36
PGPAGGRCVRWGPRE

METRN

111

Q9UJH8
PARPPSGPGGVWAAL

FAM149A

126

A5PLN7
FPRGGSAPGPDPSCW

GUCY2D

436

Q02846
TQRPPSPWPGGAGSR

MYO15A

936

Q9UKN7
CWSGPSPEGPVPLTG

GMIP

66

Q9P107
AGSPWGCPLCPDRGP

MESP2

156

Q0VG99
LPPGPGWGPRSSLSG

PCNX3

1871

Q9H6A9
PTAPPRGPGTLGWCV

MEGF8

621

Q7Z7M0
PPSWAAGAPRAGRRP

IL17D

11

Q8TAD2
ARGRWPPSSRGGGPP

IRF7

66

Q92985
RRCTGLPPCPVAGGW

CFP

246

P27918
GARPPPGTPCRVTGW

PRSS33

151

Q8NF86
RPGGDVSGWGVLPCP

LHFPL4

226

Q7Z7J7
SPGPWQSLCGLGPPC

MEF2B

306

Q02080
AGCPWPTAGPGRRSP

MEF2B

321

Q02080
GLLPCTPRGGLPGPW

EXOC7

301

Q9UPT5
RPWGFPTPGLGPATA

ACAN

441

P16112
RGSWPCGAREGPPGP

ETAA1

41

Q9NY74
PEAWLSCGPSPGPGR

CD1E

211

P15812
PRGCWQPPGSKSRPH

DCDC2B

221

A2VCK2
LWASCPPCSGRKGPP

EBI3

11

Q14213
GRCWPPVPGERSPSS

GGT5

456

P36269
GRPGGVSGPSWLQPP

EDEM1

61

Q92611
PGSYRCECRPPWVPG

LTBP3

1101

Q9NS15
CECRPPWVPGPSGRD

LTBP3

1106

Q9NS15
PCWGTGGAPAPREPY

GPR173

356

Q9NS66
CTGPARGWPRRGGGP

SCNN1D

51

P51172
TRTPPGPCCSPGVGW

CTU2

426

Q2VPK5
CPSSPGSRPCPWGLR

KIFC2

816

Q96AC6
RSPSNPPAAWGGAPC

SSPOP

2741

A2VEC9
SLRPCPGPGGEWGPW

SSPOP

3036

A2VEC9
GPWGPCSRSCGPGLA

SSPOP

4316

A2VEC9
PWPPATGPGSADGLC

PRR36

1181

Q9H6K5
GRGGGRPPPQVCPGW

PRRC2A

1171

P48634
SSSDPGPGGSGPWRP

SIPA1L2

1126

Q9P2F8
PWETRRIPGAGPGPG

PEX13

11

Q92968
WACPRLPRSPPGGAQ

RUSC1-AS1

176

Q66K80
RAGASWGSPPACPGA

MESP1

196

Q9BRJ9
WGSPPACPGARAAPE

MESP1

201

Q9BRJ9
GPAWSPGFPARPGRG

SPG7

26

Q9UQ90
PGWLGPRCEDPCPTG

SCARF1

331

Q14162
APLPAPSPRWGLGCG

LINC01465

41

Q8N7H1
GWEPRLGSPFPSGPC

TBX10

26

O75333
CPRPPRERGGAGFPW

SWI5

21

Q1ZZU3
PPVQSPGAGRSPWGR

ZC3H12A

531

Q5D1E8
PASGGGAWPSPLPSR

MKRN3

76

Q13064
LTCPGWSGPPLLPGR

TMEM88B

36

A6NKF7
RPPAGEPRFWCPECG

ZNF579

376

Q8NAF0
APSLPPRCPCGFWGS

ZFAND3

11

Q9H8U3
WPRCPVVSPGGSPGP

KMT2D

91

O14686
ENWGGGRRAPPPSPC

GRIN2C

921

Q14957