Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH9 MYH10 MYH11 MYO10 MYO3A

3.22e-06381215GO:0000146
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH9 MYH10 MYH11 DNAH10 MYO10 MYO3A KIF13A

7.62e-061181217GO:0003774
GeneOntologyMolecularFunctionATP-dependent activity

MYH9 MYH10 MYH11 DNAH10 ERCC6L MYO10 MYO3A ATP6V1H ATP11B CLPB SLFN13 SLFN11 ATP1A1 KIF13A

2.14e-0561412114GO:0140657
GeneOntologyMolecularFunctioncytoskeletal protein binding

NPHS1 MYH9 MYH10 MYH11 MYO10 NCKIPSD NUMA1 OBSCN DYSF SPTBN4 MYO3A SYNE3 TIAM1 TTLL6 NFKB1 ATP1A1 KIF13A CNN1 NIN

3.34e-05109912119GO:0008092
GeneOntologyMolecularFunctionactin filament binding

MYH9 MYH10 MYH11 MYO10 SPTBN4 MYO3A SYNE3 CNN1

7.37e-052271218GO:0051015
GeneOntologyMolecularFunctioncalmodulin binding

MYH9 MYH10 MYH11 MYO10 OBSCN MYO3A EEF2K CNN1

8.08e-052301218GO:0005516
GeneOntologyMolecularFunctionplus-end directed microfilament motor activity

MYO10 MYO3A

1.09e-0431212GO:0060002
GeneOntologyMolecularFunctionADP binding

MYH9 MYH10 MYO3A ATP1A1

2.03e-04481214GO:0043531
GeneOntologyMolecularFunctionankyrin binding

OBSCN SPTBN4 ATP1A1

3.52e-04231213GO:0030506
GeneOntologyMolecularFunctionphospholipid binding

RAPGEF6 FGD2 MYO10 NUMA1 OBSCN APOB DYSF GGA3 TPCN1 SPTBN4 TIAM1

5.05e-0454812111GO:0005543
GeneOntologyMolecularFunctionspectrin binding

NPHS1 MYO10 SPTBN4

1.13e-03341213GO:0030507
GeneOntologyBiologicalProcessregulation of cell morphogenesis

RELN MYH9 MYH10 FGD2 MYO10 OBSL1 REG1A STRIP1 SYNE3 TIAM1 SH3D19 EEF2K PRKDC BRWD1

2.86e-0930212114GO:0022604
GeneOntologyBiologicalProcesscell morphogenesis

RELN MYH9 MYH10 FGD2 MYO10 OBSL1 REG1A BCAN STRIP1 SPTBN4 TTC8 MYO3A SYNE3 TIAM1 SH3D19 EEF2K PRKDC CDH15 BRWD1 NIN

2.00e-05119412120GO:0000902
GeneOntologyBiologicalProcessmonocyte activation involved in immune response

DYSF FER1L5

3.41e-0521212GO:0002280
GeneOntologyBiologicalProcessplasma membrane repair

MYH9 MYH10 DYSF FER1L5

4.56e-05341214GO:0001778
GeneOntologyBiologicalProcesspositive regulation of cell morphogenesis

RELN OBSL1 TIAM1 EEF2K PRKDC

5.32e-05691215GO:0010770
GeneOntologyBiologicalProcessactin filament bundle distribution

MYH9 MYH10

1.02e-0431212GO:0070650
GeneOntologyCellularComponentmyosin filament

MYH9 MYH10 MYH11 OBSCN

1.19e-05251204GO:0032982
GeneOntologyCellularComponentmyosin complex

MYH9 MYH10 MYH11 MYO10 MYO3A

2.24e-05591205GO:0016459
GeneOntologyCellularComponentsupramolecular fiber

MYH9 MYH10 MYH11 DNAH10 KRT28 KLHL40 NCKIPSD NUMA1 OBSCN OBSL1 EVPL DYSF SPTBN4 MYO3A TIAM1 TTLL6 CFAP161 KIF13A NIN

4.15e-05117912019GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

MYH9 MYH10 MYH11 DNAH10 KRT28 KLHL40 NCKIPSD NUMA1 OBSCN OBSL1 EVPL DYSF SPTBN4 MYO3A TIAM1 TTLL6 CFAP161 KIF13A NIN

4.54e-05118712019GO:0099081
GeneOntologyCellularComponentCOP9 signalosome

MYH9 NCKIPSD GRAPL GRAP

6.56e-05381204GO:0008180
GeneOntologyCellularComponentmyosin II filament

MYH9 MYH10

9.77e-0531202GO:0097513
GeneOntologyCellularComponentendoplasmic reticulum lumen

PCSK1 ARSJ CALU APOB GANAB SCG2 FGA CNPY3 CERCAM

1.29e-043321209GO:0005788
GeneOntologyCellularComponentcell-cell contact zone

OBSCN OBSL1 SPTBN4 TIAM1 ATP1A1

2.09e-04941205GO:0044291
GeneOntologyCellularComponentmyosin II complex

MYH9 MYH10 MYH11

5.44e-04281203GO:0016460
GeneOntologyCellularComponentcell-cell junction

NPHS1 MYH9 OBSCN OBSL1 EVPL SPTBN4 TGM1 GJB3 TIAM1 ATP1A1 CDH15

6.04e-0459112011GO:0005911
GeneOntologyCellularComponentintercalated disc

OBSCN OBSL1 SPTBN4 ATP1A1

6.33e-04681204GO:0014704
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

MYH9 DNAH10 KRT28 NCKIPSD NUMA1 EVPL DYSF SPTBN4 MYO3A TIAM1 TTLL6 CFAP161 KIF13A NIN

6.50e-0489912014GO:0099513
GeneOntologyCellularComponentU2-type catalytic step 2 spliceosome

CWC22 SNW1 CDC40

7.37e-04311203GO:0071007
GeneOntologyCellularComponentnuclear protein-containing complex

MYH9 SETD1B NCKIPSD CWC22 ANAPC10 SYNE3 SNW1 CDC40 UPF2 SUPT5H RFXANK NFKB1 NAT10 SUPT16H GRAPL PRKDC TAF1 GRAP

8.63e-04137712018GO:0140513
GeneOntologyCellularComponentmain axon

BCAN DBH SPTBN4 TIAM1

1.73e-03891204GO:0044304
DomainMyosin_head_motor_dom

MYH9 MYH10 MYH11 MYO10 MYO3A

3.93e-06381185IPR001609
DomainMYOSIN_MOTOR

MYH9 MYH10 MYH11 MYO10 MYO3A

3.93e-06381185PS51456
DomainMyosin_head

MYH9 MYH10 MYH11 MYO10 MYO3A

3.93e-06381185PF00063
DomainMYSc

MYH9 MYH10 MYH11 MYO10 MYO3A

3.93e-06381185SM00242
DomainIQ

MYH9 MYH10 MYH11 MYO10 OBSCN MYO3A

5.73e-06711186PF00612
DomainIQ

MYH9 MYH10 MYH11 MYO10 OBSCN MYO3A

1.23e-05811186SM00015
DomainIQ_motif_EF-hand-BS

MYH9 MYH10 MYH11 MYO10 OBSCN MYO3A

2.26e-05901186IPR000048
DomainIQ

MYH9 MYH10 MYH11 MYO10 OBSCN MYO3A

2.73e-05931186PS50096
DomainMyosin_N

MYH9 MYH10 MYH11

1.06e-04151183PF02736
DomainMyosin_N

MYH9 MYH10 MYH11

1.06e-04151183IPR004009
DomainFerA

DYSF FER1L5

1.18e-0431182SM01200
DomainFerlin_A-domain

DYSF FER1L5

1.18e-0431182IPR012560
DomainFerA

DYSF FER1L5

1.18e-0431182PF08165
DomainDUF2075

SLFN13 SLFN11

1.18e-0431182PF09848
DomainDUF2075

SLFN13 SLFN11

1.18e-0431182IPR018647
DomainMyosin_tail_1

MYH9 MYH10 MYH11

1.87e-04181183PF01576
DomainMyosin_tail

MYH9 MYH10 MYH11

1.87e-04181183IPR002928
DomainMyosin-like_IQ_dom

MYH9 MYH10 MYH11

2.21e-04191183IPR027401
Domain-

MYH9 MYH10 MYH11

2.21e-041911834.10.270.10
DomainDysFC

DYSF FER1L5

2.36e-0441182SM00694
DomainDysFN

DYSF FER1L5

2.36e-0441182SM00693
DomainPeroxin/Ferlin

DYSF FER1L5

2.36e-0441182IPR006614
DomainPH

FGD2 MYO10 OBSCN SPTBN4 TIAM1 IRS2 ARHGAP21 RASAL2

3.88e-042781188SM00233
DomainFerI

DYSF FER1L5

3.91e-0451182SM01202
DomainFerB

DYSF FER1L5

3.91e-0451182SM01201
DomainFerlin_B-domain

DYSF FER1L5

3.91e-0451182IPR012561
DomainFerlin_C

DYSF FER1L5

3.91e-0451182PF16165
DomainFerlin_C

DYSF FER1L5

3.91e-0451182IPR032362
DomainFerIin_dom

DYSF FER1L5

3.91e-0451182IPR012968
DomainFerI

DYSF FER1L5

3.91e-0451182PF08151
DomainFerB

DYSF FER1L5

3.91e-0451182PF08150
DomainMyosin_S1_N

MYH10 MYH11

3.91e-0451182IPR008989
DomainPH_DOMAIN

FGD2 MYO10 OBSCN SPTBN4 TIAM1 IRS2 ARHGAP21 RASAL2

3.97e-042791188PS50003
DomainPH_domain

FGD2 MYO10 OBSCN SPTBN4 TIAM1 IRS2 ARHGAP21 RASAL2

4.07e-042801188IPR001849
DomainPH

FGD2 MYO10 OBSCN SPTBN4 TIAM1 IRS2 ARHGAP21

6.33e-042291187PF00169
DomainSpectrin_repeat

EVPL SPTBN4 SYNE3

7.97e-04291183IPR002017
DomainAlbA_2

SLFN13 SLFN11

8.14e-0471182PF04326
DomainSchlafen

SLFN13 SLFN11

8.14e-0471182IPR029684
DomainSchlafen_AAA_dom

SLFN13 SLFN11

8.14e-0471182IPR007421
DomainSPEC

EVPL SPTBN4 SYNE3

1.07e-03321183SM00150
DomainSpectrin/alpha-actinin

EVPL SPTBN4 SYNE3

1.07e-03321183IPR018159
DomainMIF4G

CWC22 UPF2

1.72e-03101182SM00543
DomainJmjN

KDM4C KDM5C

1.72e-03101182SM00545
DomainMIF4G

CWC22 UPF2

1.72e-03101182PF02854
DomainJmjN

KDM4C KDM5C

1.72e-03101182PF02375
DomainMIF4G-like_typ-3

CWC22 UPF2

1.72e-03101182IPR003890
DomainJMJN

KDM4C KDM5C

1.72e-03101182PS51183
DomainJmjN

KDM4C KDM5C

1.72e-03101182IPR003349
DomainAnk_2

ASZ1 TEX14 CLPB RFXANK NFKB1 PPP1R16B

2.45e-032151186PF12796
DomainP-loop_NTPase

RALB MYH9 MYH10 MYH11 DNAH10 ERCC6L MYO10 MYO3A CLPB SLFN13 SLFN11 KIF13A CARD14

2.72e-0384811813IPR027417
DomainAnk

ASZ1 TEX14 CLPB RFXANK NFKB1 PPP1R16B

3.28e-032281186PF00023
Domain-

FGD2 MYO10 OBSCN SPTBN4 TIAM1 IRS2 ARHGAP21 RASAL2

3.40e-0339111882.30.29.30
Domainzf-C2H2_6

ZNF184 ZNF316 ZNF416 ZNF546 ZNF26 ZNF761 ZNF548

3.82e-033141187PF13912
Domain-

CWC22 UPF2

3.94e-031511821.25.40.180
DomainMIF4-like

CWC22 UPF2

3.94e-03151182IPR016021
DomainTPR_REGION

DNAH10 ERCC6L TTC8 PRKDC EMC2

3.97e-031651185PS50293
DomainTPR

DNAH10 ERCC6L TTC8 PRKDC EMC2

3.97e-031651185PS50005
Domain-

ASZ1 TEX14 CLPB RFXANK NFKB1 PPP1R16B

4.94e-0324811861.25.40.20
DomainANK

ASZ1 TEX14 CLPB RFXANK NFKB1 PPP1R16B

5.23e-032511186SM00248
DomainANK_REPEAT

ASZ1 TEX14 CLPB RFXANK NFKB1 PPP1R16B

5.43e-032531186PS50088
DomainAnkyrin_rpt-contain_dom

ASZ1 TEX14 CLPB RFXANK NFKB1 PPP1R16B

5.54e-032541186IPR020683
DomainANK_REP_REGION

ASZ1 TEX14 CLPB RFXANK NFKB1 PPP1R16B

5.54e-032541186PS50297
DomainPH_dom-like

FGD2 MYO10 OBSCN SPTBN4 TIAM1 IRS2 ARHGAP21 RASAL2

5.67e-034261188IPR011993
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

EPRS1 PTGES2 RELN KDM4C OBSL1 NCAPH2 CUEDC1 SPTBN4 TIAM1 CLPB SUPT5H SCG2 SH3D19 PPP1R16B CERCAM PRKDC TAF1 WDR17 PADI2 ARHGAP21 RASAL2 BRWD1

9.82e-1012851242235914814
Pubmed

LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.

EPRS1 MYH9 MYH10 MYH11 NUMA1 EVPL TGM1 GANAB NAT10 SUPT16H PRKDC ATP1A1

2.43e-093271241231409639
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

EPRS1 MYH9 MYH10 DNAH10 CALU NUMA1 APOB CWC22 ATP6V1H GANAB SNW1 CDC40 CLPB SUPT5H NAT10 SUPT16H PRKDC ATP1A1 EMC2 ZNF512 RASAL2

3.32e-0814251242130948266
Pubmed

Effects of h1-calponin ablation on the contractile properties of bladder versus vascular smooth muscle in mice lacking SM-B myosin.

MYH10 MYH11 CNN1

4.42e-083124316973711
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

EPRS1 MYH9 MYH10 MYH11 NUMA1 TIAM1 SUPT16H PRKDC ATP1A1

5.02e-08202124933005030
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

MYH9 MYH10 NUMA1 SNW1 SUPT5H NAT10 SUPT16H PRKDC TAF1 ZNF512

7.84e-082831241030585729
Pubmed

Loss of smooth muscle myosin heavy chain results in the bladder and stomach developing lesion during foetal development in mice.

MYH9 MYH11 CNN1

1.76e-074124329932067
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

EPRS1 MYH9 MYH10 RAPGEF6 ERCC6L NUMA1 GGA3 SNW1 SH3D19 NAT10 IRS2 SLFN11 PRKDC ATP1A1 ARHGAP21 HERC5

2.34e-079341241633916271
Pubmed

Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach.

CLGN CALU DBH GANAB PRKDC ATP1A1

2.55e-0773124623464991
Pubmed

Telokin expression is restricted to smooth muscle tissues during mouse development.

MYH9 MYH10 MYH11

4.40e-075124311121372
Pubmed

Proteome analysis of the HIV-1 Gag interactome.

EPRS1 MYH9 MYH10 NAT10 HERC5

5.16e-0744124525010285
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

EPRS1 MYH9 MYH10 MYH11 NUMA1 UPF2 PRKDC ATP1A1

6.97e-07202124824639526
Pubmed

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.

MYH9 MYH10 MYH11 APOB FGA CNN1

1.01e-0692124637343697
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

EPRS1 MYH9 MYH10 MYH11 MYO10 NUMA1 OBSL1 APOB TGM1 GANAB NAT10 SUPT16H PRKDC ATP1A1 HERC5

1.56e-069491241536574265
Pubmed

Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction.

MYH9 MYH10 MYH11

2.45e-068124333424621
Pubmed

Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.

EPRS1 MYH9 MYH10 CLGN APOB GANAB PRKDC ATP1A1

2.86e-06244124828902428
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

EPRS1 KDM5C NUMA1 NCAPH2 SNW1 SUPT5H NAT10 PRKDC TAF1

3.20e-06332124932786267
Pubmed

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

EPRS1 MYH9 MYH10 CALU PRKDC ATP1A1

4.32e-06118124627377895
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

EPRS1 MYH9 ERCC6L NUMA1 ATP6V1H GANAB SH3D19 IRS2 PRKDC ATP1A1 ARHGAP21 RASAL2

9.21e-067081241239231216
Pubmed

Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.

MYH9 MYH10 MYH11

9.51e-061212438424456
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

EPRS1 MYH9 MYH10 CALU NUMA1 GANAB TRIM56 NAT10 SUPT16H PRKDC HERC5

1.09e-056011241133658012
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CALU KDM5C ZNF316 OBSL1 ANAPC10 TRIM56 NAT10 SUPT16H IRS2 SLFN11 TAF1 PADI2 CDH15 BRWD1 NIN

1.09e-0511161241531753913
Pubmed

Angiotensin-II mediates nonmuscle myosin II activation and expression and contributes to human keloid disease progression.

MYH9 MYH10

1.26e-052124221792479
Pubmed

Micro-environmental control of cell migration--myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics.

MYH9 MYH10

1.26e-052124222328520
Pubmed

Nonmuscle myosin II-B is required for normal development of the mouse heart.

MYH9 MYH10

1.26e-05212429356462
Pubmed

Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis.

NFKB1 CARD14

1.26e-052124222521419
Pubmed

Mechanisms underlying Myosin 10's contribution to the maintenance of mitotic spindle bipolarity.

MYH10 MYO10

1.26e-052124238019611
Pubmed

Dorsal root ganglion neurons react to semaphorin 3A application through a biphasic response that requires multiple myosin II isoforms.

MYH9 MYH10

1.26e-052124219109430
Pubmed

Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling.

GRAPL GRAP

1.26e-052124219836472
Pubmed

Rho kinase differentially regulates phosphorylation of nonmuscle myosin II isoforms A and B during cell rounding and migration.

MYH9 MYH10

1.26e-052124217020881
Pubmed

Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction.

GRAPL GRAP

1.26e-052124211971956
Pubmed

The distinct roles of myosin IIA and IIB under compression stress in nucleus pulposus cells.

MYH9 MYH10

1.26e-052124233415745
Pubmed

ERCC6L promotes cell growth and metastasis in gastric cancer through activating NF-κB signaling.

ERCC6L NFKB1

1.26e-052124234425559
Pubmed

Mutations in non-muscle myosin 2A disrupt the actomyosin cytoskeleton in Sertoli cells and cause male infertility.

MYH9 MYH10

1.26e-052124233188738
Pubmed

Nonmuscle myosin IIA and IIB differentially contribute to intrinsic and directed migration of human embryonic lung fibroblasts.

MYH9 MYH10

1.26e-052124229486156
Pubmed

Myosin heavy chain gene expression in normal and hyperplastic human prostate tissue.

MYH10 MYH11

1.26e-052124210906735
Pubmed

Redistribution of insoluble interphotoreceptor matrix components during photoreceptor differentiation in the mouse retina.

MYH9 MYH10

1.26e-05212428089273
Pubmed

Expression of four myosin heavy chain isoforms with development in mouse uterus.

MYH9 MYH10

1.26e-05212428402956
Pubmed

Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes.

MYH9 MYH10

1.26e-052124227737892
Pubmed

Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis.

MYH10 MYH11

1.26e-05212427916668
Pubmed

Dynamic assembly properties of nonmuscle myosin II isoforms revealed by combination of fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy.

MYH9 MYH10

1.26e-052124221106542
Pubmed

Conditional expression of a truncated fragment of nonmuscle myosin II-A alters cell shape but not cytokinesis in HeLa cells.

MYH9 MYH10

1.26e-052124211029059
Pubmed

Non-muscle myosin heavy chain IIA and IIB interact and co-localize in living cells: relevance for MYH9-related disease.

MYH9 MYH10

1.26e-052124216596254
Pubmed

Detection of Grb-2-related adaptor protein gene (GRAP) and peptide molecule in salivary glands of MRL/lpr mice and patients with Sjögren's syndrome.

GRAPL GRAP

1.26e-052124215174222
Pubmed

Constriction velocities of renal afferent and efferent arterioles of mice are not related to SMB expression.

MYH10 MYH11

1.26e-052124216316347
Pubmed

Carboxyl-terminal-dependent recruitment of nonmuscle myosin II to megakaryocyte contractile ring during polyploidization.

MYH9 MYH10

1.26e-052124225185263
Pubmed

Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy.

DYSF PRKDC

1.26e-052124221364666
Pubmed

Non-Muscle Myosin II Isoforms Have Different Functions in Matrix Rearrangement by MDA-MB-231 Cells.

MYH9 MYH10

1.26e-052124226136073
Pubmed

Myosin II activity regulates neurite outgrowth and guidance in response to chondroitin sulfate proteoglycans.

MYH9 MYH10

1.26e-052124222191382
Pubmed

Myosin II isoforms play distinct roles in adherens junction biogenesis.

MYH9 MYH10

1.26e-052124231486768
Pubmed

Differential expression and functions of cortical myosin IIA and IIB isotypes during meiotic maturation, fertilization, and mitosis in mouse oocytes and embryos.

MYH9 MYH10

1.26e-05212429725909
Pubmed

Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain.

MYH9 MYH10

1.26e-052124223128239
Pubmed

Disparity between microRNA levels and promoter strength is associated with initiation rate and Pol II pausing.

NFKB1 TAF1

1.26e-052124223831825
Pubmed

Differential localization of myosin-II isozymes in human cultured cells and blood cells.

MYH9 MYH10

1.26e-05212427699007
Pubmed

Grb2-related adaptor protein GRAP is a novel regulator of liver fibrosis.

GRAPL GRAP

1.26e-052124237343720
Pubmed

Conditional Myh9 and Myh10 inactivation in adult mouse renal epithelium results in progressive kidney disease.

MYH9 MYH10

1.26e-052124233001861
Pubmed

Distinct roles for non-muscle myosin II isoforms in mouse hepatic stellate cells.

MYH9 MYH10

1.26e-052124220932596
Pubmed

The C-terminal tail region of nonmuscle myosin II directs isoform-specific distribution in migrating cells.

MYH9 MYH10

1.26e-052124218843042
Pubmed

Human nonmuscle myosin heavy chains are encoded by two genes located on different chromosomes.

MYH9 MYH10

1.26e-05212421860190
Pubmed

Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response.

SLFN13 SLFN11

1.26e-052124237833372
Pubmed

Different contributions of nonmuscle myosin IIA and IIB to the organization of stress fiber subtypes in fibroblasts.

MYH9 MYH10

1.26e-052124229467250
Pubmed

Absence of T and B lymphocytes modulates dystrophic features in dysferlin deficient animal model.

DYSF PRKDC

1.26e-052124222465227
Pubmed

Non-muscle myosin IIB is essential for cytokinesis during male meiotic cell divisions.

MYH9 MYH10

1.26e-052124222820068
Pubmed

Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis.

MYH9 MYH10

1.26e-052124222393000
Pubmed

Nonmuscle myosin IIA and IIB differentially modulate migration and alter gene expression in primary mouse tumorigenic cells.

MYH9 MYH10

1.26e-052124230995168
Pubmed

Concerted actions of distinct nonmuscle myosin II isoforms drive intracellular membrane remodeling in live animals.

MYH9 MYH10

1.26e-052124228600434
Pubmed

Single quantum dot tracking reveals that an individual multivalent HIV-1 Tat protein transduction domain can activate machinery for lateral transport and endocytosis.

MYH9 MYH10

1.26e-052124223732912
Pubmed

Ablation and mutation of nonmuscle myosin heavy chain II-B results in a defect in cardiac myocyte cytokinesis.

MYH9 MYH10

1.26e-052124212893741
Pubmed

Expression of the smooth muscle cell calponin gene marks the early cardiac and smooth muscle cell lineages during mouse embryogenesis.

MYH11 CNN1

1.26e-05212428636144
Pubmed

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.

SLFN13 SLFN11

1.26e-052124229563550
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MYH10 SETD1B MYO10 OBSL1 STRIP1 GGA3 GANAB BTBD7 ARHGAP21

1.64e-05407124912693553
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

ERCC6L CALU NUMA1 CWC22 STRIP1 CCNA2 TGM1 ANAPC10 GANAB SNW1 CDC40 DNAJA4 SH3D19 FGA PRKDC

1.64e-0511551241520360068
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

EPRS1 MYH9 MYH10 NUMA1 GANAB SNW1 CDC40 NAT10 SUPT16H PRKDC ATP1A1

1.97e-056411241136057605
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CCPG1 CALU OBSL1 GANAB SYNE3 SNW1 TIAM1 CLPB DNAJA4 NAT10 SUPT16H EEF2K EMC2 ZNF512 RASAL2 HERC5 NIN

2.22e-0514871241733957083
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

MYH9 NUMA1 EVPL APOB TGM1 GANAB SNW1 NAT10 SUPT16H FGA PRKDC

2.31e-056521241131180492
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

MYH9 MYH10 CALU NUMA1 GANAB SNW1 CDC40 CLPB SUPT5H NAT10 PRKDC

2.34e-056531241133742100
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYH9 MYH10 NUMA1 GANAB SNW1 SUPT5H NAT10 PRKDC ATP1A1 ZNF512 HERC5

2.34e-056531241122586326
Pubmed

Genome-wide association of body fat distribution in African ancestry populations suggests new loci.

PCSK1 MYH11 ASZ1

2.39e-0516124323966867
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

EPRS1 RAPGEF6 ERCC6L NUMA1 GGA3 SNW1 SH3D19 NAT10 PRKDC TAF1

2.89e-055491241038280479
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

MYH9 CCPG1 KDM5C CCNA2 TIAM1 EEF2K SLFN11

3.36e-05250124733536335
Pubmed

FAP is critical for ovarian cancer cell survival by sustaining NF-κB activation through recruitment of PRKDC in lipid rafts.

NFKB1 PRKDC

3.77e-053124236494579
Pubmed

Mmu-miR-125b overexpression suppresses NO production in activated macrophages by targeting eEF2K and CCNA2.

CCNA2 EEF2K

3.77e-053124227020049
Pubmed

Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II.

MYH9 MYH10

3.77e-053124220685736
Pubmed

Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex.

OBSCN OBSL1

3.77e-053124220133654
Pubmed

Nonmuscle myosin IIA facilitates vesicle trafficking for MG53-mediated cell membrane repair.

MYH9 DYSF

3.77e-053124222253476
Pubmed

Correlation between the clinical phenotype of MYH9-related disease and tissue distribution of class II nonmuscle myosin heavy chains.

MYH9 MYH10

3.77e-053124215177565
Pubmed

Myosin IIA suppresses glioblastoma development in a mechanically sensitive manner.

MYH9 MYH10

3.77e-053124231235578
Pubmed

Both Myosin-10 isoforms are required for radial neuronal migration in the developing cerebral cortex.

MYH10 MYO10

3.77e-053124223300110
Pubmed

Local and global dynamics of the basement membrane during branching morphogenesis require protease activity and actomyosin contractility.

MYH9 MYH10

3.77e-053124225158168
Pubmed

HBx-induced MiR-1269b in NF-κB dependent manner upregulates cell division cycle 40 homolog (CDC40) to promote proliferation and migration in hepatoma cells.

CDC40 NFKB1

3.77e-053124227349221
Pubmed

Schlafen 11 triggers innate immune responses through its ribonuclease activity upon detection of single-stranded DNA.

SLFN13 SLFN11

3.77e-053124238875319
Pubmed

Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.

OBSCN OBSL1

3.77e-053124227989621
Pubmed

Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation.

EEF1AKMT4-ECE2 EEF1AKMT4

3.77e-053124228520920
Pubmed

Vertebrate nonmuscle myosin II isoforms rescue small interfering RNA-induced defects in COS-7 cell cytokinesis.

MYH9 MYH10

3.77e-053124215774463
Pubmed

Nephrin deficiency activates NF-kappaB and promotes glomerular injury.

NPHS1 NFKB1

3.77e-053124219497968
Pubmed

Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.

OBSCN OBSL1

3.77e-053124231098411
Pubmed

Mosaic loss of non-muscle myosin IIA and IIB is sufficient to induce mammary epithelial proliferation.

MYH9 MYH10

3.77e-053124228821574
Pubmed

Lens fiber cell elongation and differentiation is associated with a robust increase in myosin light chain phosphorylation in the developing mouse.

MYH9 MYH10

3.77e-053124217459090
Pubmed

Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family.

MYH9 MYH10

3.77e-053124214594953
Pubmed

The depletion of Circ-PRKDC enhances autophagy and apoptosis in T-cell acute lymphoblastic leukemia via microRNA-653-5p/Reelin mediation of the PI3K/AKT/mTOR signaling pathway.

RELN PRKDC

3.77e-053124233615686
InteractionITGB1 interactions

RELN MYH9 MYH10 MYO10 CALU NCKIPSD GGA3 GANAB SYNE3 UPF2 SUPT5H SUPT16H PRKDC EMC2 BRWD1

1.60e-0840012015int:ITGB1
InteractionLRRC31 interactions

EPRS1 MYH9 MYH10 MYH11 NUMA1 TIAM1 SUPT16H PRKDC ATP1A1

3.86e-062051209int:LRRC31
InteractionH3C15 interactions

EPRS1 PTGES2 MYH10 KDM5C NUMA1 OBSL1 NAT10 SUPT16H SLFN11

4.18e-062071209int:H3C15
InteractionLOXL2 interactions

EPRS1 MYH9 MYH10 MYH11 NUMA1 EVPL TGM1 GANAB NAT10 SUPT16H PRKDC ATP1A1

6.24e-0641012012int:LOXL2
InteractionITGB3 interactions

MYH9 MYH10 MYO10 GANAB SUPT5H FGA PRKDC ATP1A1

8.19e-061701208int:ITGB3
InteractionTRIM33 interactions

MYH9 MYH10 CALU KDM5C CCNA2 GANAB SUPT16H FGA SLFN11 PRKDC ATP1A1 NIN

1.69e-0545312012int:TRIM33
InteractionH2BC4 interactions

EPRS1 RALB PTGES2 MYH9 MYH10 MYH11 NUMA1 UPF2 SLFN11

2.52e-052591209int:H2BC4
InteractionCIT interactions

MYH9 MYH10 MYH11 CLGN CALU NCKIPSD NUMA1 OBSL1 APOB SPTBN4 GANAB SNW1 CDC40 CLPB SUPT5H NAT10 SUPT16H CNPY3 PRKDC ATP1A1 RASAL2 NIN

4.15e-05145012022int:CIT
InteractionPPP2R1A interactions

MYH9 MYH10 OBSL1 NCAPH2 STRIP1 ANAPC10 GANAB SNW1 CDC40 SUPT5H SLFN11 MINDY4 TAF1 ATP1A1

4.21e-0566512014int:PPP2R1A
InteractionCDK9 interactions

MYH9 MYH10 SETD1B MYO10 NUMA1 CCNA2 ATP6V1H GANAB SNW1 SUPT5H NFKB1 SUPT16H PRKDC ATP1A1

5.80e-0568512014int:CDK9
InteractionRANBP2 interactions

RALB NUMA1 OBSL1 SYNE3 SNW1 SUPT16H SLFN11 PRKDC TAF1 EMC2

6.08e-0536112010int:RANBP2
InteractionNAA40 interactions

EPRS1 MYH9 MYH10 RAPGEF6 ERCC6L NUMA1 GGA3 SNW1 SH3D19 NAT10 SUPT16H IRS2 SLFN11 PRKDC ATP1A1 ARHGAP21 HERC5

6.81e-0597812017int:NAA40
GeneFamilyMyosin heavy chains

MYH9 MYH10 MYH11

4.54e-05158631098
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

FGD2 MYO10 SPTBN4 TIAM1 IRS2 ARHGAP21 RASAL2

5.65e-05206867682
GeneFamilyFerlin family

DYSF FER1L5

3.31e-046862828
GeneFamilySchlafen family

SLFN13 SLFN11

4.62e-0478621110
CoexpressionGSE4142_PLASMA_CELL_VS_MEMORY_BCELL_UP

MYH11 ARSJ FGD2 CRYBA1 MYO3A GJB3 CFAP161 RASAL2

4.68e-061991238M6395
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic-6|TCGA-Mesothelium / Sample_Type by Project: Shred V9

ERCC6L CALU DYSF SYT15B CNN1 NIN

5.35e-06159123685501c636cd04f15ba1be24df1ba7ac909633ce8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN SYT15B TTLL6 GRAPL PPP1R16B GRAP

6.62e-0616512366a621b300442c52adfc15b61d3a6d3a3cb00099f
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERCC6L CARMIL3 ZNF184 EVPL ZNF416 CCNA2

8.97e-0617412362a96a4fd7d9ef05213b26103c689cf3a26968713
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCSK1 ARSJ EVPL SPTBN4 GJB3 SCG2

1.05e-0517912368ce5000088b727783a0619baa16a2cd036d21f54
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH10 ZNF184 CDC40 DNAJA4 SCG2 IRS2

1.31e-051861236f5468e03321ea2083e223eb0d92c3a9307039569
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYH9 MYH10 MYH11 KIF13A CNN1 RASAL2

1.43e-0518912366b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN DYSF SYT15B GRAPL PPP1R16B RASAL2

1.52e-051911236f663131a4810584c5854bd64ee7991a237b7707f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN DYSF SYT15B GRAPL PPP1R16B RASAL2

1.66e-051941236b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN DYSF GRAPL PPP1R16B RASAL2 GRAP

1.66e-051941236ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN DYSF SYT15B GRAPL PPP1R16B RASAL2

1.66e-051941236fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCellfacs-Bladder-nan-3m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCPG1 MYH10 CALU GANAB SH3D19 CERCAM

1.76e-05196123644f5b1b474399c9316729155f2ea95a82ca66e30
ToppCellfacs-Bladder-nan-3m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCPG1 MYH10 CALU GANAB SH3D19 CERCAM

1.76e-051961236c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCellCV-Moderate|CV / Virus stimulation, Condition and Cluster

PTGES2 CARMIL3 DNPH1 NFKB1 CERCAM IL9R

1.81e-0519712368747a57ded96175a8365f066101ce2af80c8081d
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-C1ql2-Excitatory_Neuron.Slc17a7.C1ql2-Cck_(Dentate_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

KRT28 DBH GJB3 FGA CDH15

2.95e-05129123508ecebb7f09d105dfdfd2191fc310910d3baec0f
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH11 NCKIPSD STRIP1 TPCN1 CNN1

3.30e-05132123546c80eab16a70da9f363a9fbdf50bccab0b287d7
ToppCellLPS-IL1RA+antiTNF-Unknown|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH11 NCKIPSD STRIP1 TPCN1 CNN1

3.30e-051321235a022c3c41654166cb106f27dc54fa88e8c40f898
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

EPRS1 KLHL40 PYROXD2 CNN1 PRIMPOL

7.30e-051561235029ba0832ee9c4a2c85620e4df2260e02d86b45c
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

EPRS1 KLHL40 PYROXD2 CNN1 PRIMPOL

7.30e-0515612355df19a235843829f5a1a90ca21b0964ef8b4e115
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FGD2 GRAPL PPP1R16B IL9R GRAP

9.52e-0516512357039bb5a7af4684fbd1192230864e5cd6936e83c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FGD2 GRAPL PPP1R16B IL9R GRAP

9.52e-051651235d2c79653710b139794170f3d72f11392fc548ac7
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK1 ERCC6L CCNA2 PADI2 IL9R

1.01e-041671235859dfe0764cb69de27e79e1c1aa65f9d538f79ea
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYH11 RAPGEF6 KLHL40 CCNA2 CNN1

1.01e-0416712354ae9f2c5df13463709ea880ab035965fd99e7626
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYH11 RAPGEF6 KLHL40 CCNA2 CNN1

1.01e-0416712354e58f9bf1e9d47720c871776ec34513ded4de9b7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPRS1 MYH11 RAPGEF6 KDM5C IRS2

1.01e-041671235ced6ed9b412739c6ced622523347c10295edbf53
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERCC6L CCNA2 TGM1 TTLL6 CFAP161

1.16e-041721235c0bda7153e02bee7d0326138cc684151c404c2a1
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

RELN DYSF SYNE3 HERC5 GRAP

1.16e-041721235c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCKIPSD TIAM1 PPP1R16B PRIMPOL HERC5

1.16e-041721235eee45759284baa3ed77da6a5fbcc4f8f6c553106
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN DYSF SYT15B GRAPL PPP1R16B

1.16e-041721235c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 MYH11 GUCA1B WDR17 CNN1

1.22e-041741235778e0317c0c63fa4efd74114feb760975b819d92
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH11 KRT28 APOB TEX14 CNN1

1.22e-041741235c529f3674b784f872f4387ffdeb46aecb619976b
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DYSF SLFN13 PPP1R16B RASAL2 GRAP

1.22e-04174123542735f6a8e5ec36dd3d35aceea6d37cf3eaa1871
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH11 ERCC6L DNPH1 CCNA2 CNN1

1.29e-04176123545c6983ab671b0f306e7390320bd84f848e474cc
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK1 MYH11 APOB FGA CNN1

1.32e-041771235928118b0ed120ec01c7d753ce523ab609ac24e5f
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYH11 MYO10 PPP1R16B PADI2 RASAL2

1.39e-04179123514fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYH11 MYO10 GRAPL PPP1R16B PADI2

1.51e-0418212357b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF GRAPL PPP1R16B RASAL2 GRAP

1.54e-041831235dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF GRAPL PPP1R16B RASAL2 GRAP

1.54e-0418312354759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

MYH11 MYO10 NCKIPSD OBSCN CNN1

1.54e-041831235fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN DYSF GRAPL PPP1R16B GRAP

1.63e-041851235fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RELN DYSF GRAPL PPP1R16B GRAP

1.63e-0418512353be9e05b929ac4d956b1d53284072f668a6c1959
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RELN DYSF GRAPL PPP1R16B GRAP

1.63e-041851235c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN DYSF GRAPL PPP1R16B GRAP

1.67e-0418612359d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH9 MYO10 DYSF PPP1R16B RASAL2

1.71e-0418712350ef82111b9049cc7ee78d64d240e1f10ab14d6b6
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

MYH10 MYH11 KIF13A CNN1 RASAL2

1.75e-04188123534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RELN DYSF GRAPL PPP1R16B GRAP

1.80e-0418912350d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN MYH11 CARMIL3 MYO3A SCG2

1.80e-041891235f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF TIAM1 GRAPL PPP1R16B CFAP161

1.84e-041901235656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCellwk_08-11-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RELN DYSF GRAPL PPP1R16B GRAP

1.84e-041901235279c5f68b993dc7adbf9aa69fffb1321cdebc48a
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH9 MYH10 MYH11 CALU NIN

1.84e-041901235d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellwk_08-11-Endothelial-Lymph_endothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RELN DYSF GRAPL PPP1R16B GRAP

1.84e-041901235d7f1dc032d161529559e01832d1a3112c6f6cc1a
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DPP3 ATP11B SLFN11 IL9R NIN

1.93e-041921235445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF GRAPL PPP1R16B CFAP161 RASAL2

1.93e-041921235c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCellsevere-Myeloid-Neutrophils_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MYH9 DYSF ATP11B IRS2 PADI2

1.98e-041931235f4d43dfbf4115dd0f843ea5cf08049220342a047
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF SYT15B GRAPL PPP1R16B GRAP

1.98e-0419312351f978e102a029a6beb10913052cd0a20c7253e8e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF GRAPL PPP1R16B CFAP161 RASAL2

1.98e-04193123552e918884877b6659cdca0496390e440f73694a9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF GRAPL PPP1R16B CFAP161 RASAL2

2.03e-041941235f76808666fb875fc787751cbfd924d9be20a8192
ToppCellControl-Classical_Monocyte|Control / Disease condition and Cell class

DYSF TPCN1 IRS2 KIF13A PADI2

2.03e-0419412359e33e1b54b4114f9e6981819834bb796ed7192b5
ToppCellsevere-Myeloid-Neutrophils_3|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MYH9 DYSF ATP11B IRS2 PADI2

2.03e-0419412351f8edab1c8ba48bc0114429ea47aab378b5830b7
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 CARMIL3 DPP3 SCG2 ATP1A1

2.03e-0419412350b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

OBSCN DYSF SH3D19 GRAPL CFAP161

2.03e-04194123540842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF GRAPL PPP1R16B CFAP161 RASAL2

2.03e-041941235f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF GRAPL PPP1R16B CFAP161 RASAL2

2.03e-041941235a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

RELN DYSF SH3D19 GRAPL CFAP161

2.07e-041951235094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RELN DYSF GRAPL PPP1R16B GRAP

2.12e-04196123509a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RELN DYSF GRAPL PPP1R16B GRAP

2.12e-041961235e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

RELN MYO10 GRAPL PPP1R16B RASAL2

2.12e-041961235e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF GRAPL PPP1R16B CFAP161 RASAL2

2.12e-04196123522767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN DYSF GRAPL PPP1R16B RASAL2

2.12e-0419612358f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN DYSF GRAPL PPP1R16B RASAL2

2.12e-04196123548b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCellcontrol-immature_Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ERCC6L KDM5C GGA3 CLPB NFKB1

2.12e-041961235e34fd3e7a5b1c22a81fd3208e6d58bdb846d51c4
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARSJ CALU SCG2 CNN1 CDH15

2.12e-041961235b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellFetal_29-31_weeks-Endothelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RELN DYSF GRAPL PPP1R16B CFAP161

2.12e-0419612353981f6c7487598f4f7ce4650ac0ac5bd41481d66
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN DYSF GRAPL PPP1R16B RASAL2

2.12e-041961235473980c827443464d08a0be28c53e3536369b12a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF GRAPL PPP1R16B CFAP161 RASAL2

2.12e-041961235adee900dcd16dbaba15c58bdcace09ba20214950
ToppCellEndothelial|World / Lineage, Cell type, age group and donor

RELN DYSF GRAPL PPP1R16B CFAP161

2.12e-04196123596c6d78482a130ce4e29f6629972a06d10d7530e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF GRAPL PPP1R16B CFAP161 RASAL2

2.18e-041971235cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellBL|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RALB MYH9 DYSF NFKB1 NIN

2.18e-0419712351acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCellCD8+_Memory_T_cell-CV-3|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

CARMIL3 DNPH1 NFKB1 CERCAM IL9R

2.18e-0419712359fe3d53346a95c1bbb0fc6a2f2e974889873424b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF GRAPL PPP1R16B CFAP161 RASAL2

2.18e-041971235412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-Treg|ICU-SEP / Disease, condition lineage and cell class

OBSCN DPP3 PPP1R16B KLHL34 HERC5

2.18e-041971235c3ee2d522fbfe67069ddba2d1abfc4f5ca230c26
ToppCellCV-Moderate-3|CV / Virus stimulation, Condition and Cluster

CARMIL3 DNPH1 NFKB1 CERCAM IL9R

2.18e-0419712357031286e300eaccf73b927939f8de3a9d2d5fc74
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RELN DYSF GRAPL PPP1R16B GRAP

2.23e-0419812359ab0db78394e730f6866b2db80047149024ad5f6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF GRAPL PPP1R16B CFAP161 RASAL2

2.23e-0419812350a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RELN DYSF GRAPL PPP1R16B GRAP

2.23e-041981235e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellsevere-Myeloid-Neutrophils_4|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RALB MYH9 DYSF ATP11B PADI2

2.28e-04199123550242666def13e5d4149c563ae000d6768f086f7
ToppCellControl-Control-Myeloid-Neutrophil|Control / Disease, condition lineage and cell class

RALB MYH9 DYSF PADI2 NIN

2.33e-04200123595c41f147a1594d49e73cb56d86d301c3115ce20
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RELN DYSF GRAPL PPP1R16B GRAP

2.33e-042001235f99d0d3f51b4893fa7898c5b435494358a654cbd
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RELN DYSF GRAPL PPP1R16B GRAP

2.33e-042001235e65d4ae3d48f68c12edd5dc2c2f4e25e4acfadf1
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Lymphatic|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

RELN DYSF GRAPL PPP1R16B GRAP

2.33e-0420012354ec8e30dd241d83a1bba1c5967b6a4656afbfafd
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Serous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KDM4C NCKIPSD OBSL1 SPTBN4 PADI2

2.33e-04200123561bae10c8b12196d9cee766897971b81cb897191
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PCSK1 ARSJ CALU OBSL1 SCG2

2.33e-0420012355a5d70bfb6d253f272cc1f8516205fcfe8106291
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Macroglial-Glia_progenitor_cell|3m / Sample Type, Dataset, Time_group, and Cell type.

CCPG1 CALU OBSL1 BCAN HERC5

2.33e-042001235c5afba198818d02b4e79956edd7e77ebff74fc2e
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Zbtb20_(Ventral_Hippocampus)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GUCA1B FGA CFAP161 CDH15

2.45e-041101234ff196c71aa2a21cdd812958bd163fa6b91bd2352
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GUCA1B FGA CFAP161 CDH15

2.45e-041101234438bf761ab0a25e3dc9244c23ae2c2d68a169c7f
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Zbtb20_(Ventral_Hippocampus)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GUCA1B FGA CFAP161 CDH15

2.45e-04110123446635a130453c2fa304f0e09561b2a267c9ceb31
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GUCA1B FGA CFAP161 CDH15

2.45e-0411012343639fb5fc02eca509cb220295bc3e6064c23baab
Drugformycin triphosphate

MYH9 MYH10 MYH11 MYO10 MYO3A

6.95e-06511195CID000122274
DrugMethyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A

CLGN MYO10 NUMA1 BCAN TEX14 CUEDC1 IRS2 RASAL2

8.10e-0619311983850_UP
DrugBacitracin [1405-87-4]; Up 200; 2.8uM; MCF7; HT_HG-U133A

PIDD1 EVPL NCAPH2 DYSF CHRNA2 GJB3 SCG2 IRS2

8.73e-0619511987448_UP
DrugThiocolchicoside [602-41-5]; Down 200; 7uM; HL60; HG-U133A

RALB SETD1B CALU KDM5C PIDD1 NCAPH2 UPF2 HERC5

8.73e-0619511981726_DN
DrugPentamidine isethionate [140-64-7]; Down 200; 6.8uM; MCF7; HT_HG-U133A

CLGN MYO10 NCKIPSD PIDD1 NCAPH2 BTBD7 CNPY3 RASAL2

9.07e-0619611982834_DN
Drugpurealin

MYH9 MYH10 MYH11 MYO10 MYO3A

1.32e-05581195CID006419303
Drug125I-DLT

RELN CALU APOB

2.23e-05111193CID000126958
DrugAC1L22WP

EVPL APOB CRYBA1 TGM1 FGA

2.48e-05661195CID000065254
Drug3-methyl-2-pentanol

GRAPL GRAP

2.71e-0521192CID000011261
DiseaseHyalinosis, Segmental Glomerular

NPHS1 MYH9 MYH10

1.90e-04281183C0086432
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

DYSF FER1L5

3.29e-0471182DOID:11724 (implicated_via_orthology)
DiseaseFocal glomerulosclerosis

NPHS1 MYH9 MYH10

4.04e-04361183C0017668
DiseaseOligospermia

TPCN1 BRWD1

1.02e-03121182C0028960
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

PTGES2 CALU NCKIPSD DYSF CWC22 SH3D19 BRWD1

1.13e-033981187EFO_0003756, EFO_0003888, EFO_0004337
Diseasealcohol use disorder (implicated_via_orthology)

KDM4C KDM5C DBH CHRNA2 ATP1A1

1.15e-031951185DOID:1574 (implicated_via_orthology)
DiseaseIschemic stroke, plasminogen activator inhibitor 1 measurement

TRIM56 FGA

1.83e-03161182EFO_0004792, HP_0002140
Diseaseposterior cingulate cortex volume measurement

KDM4C NIN

2.07e-03171182EFO_0010324
Diseasebrain age measurement

EEF1AKMT4-ECE2 EEF1AKMT4

2.87e-03201182EFO_0010602
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

KDM5C PIDD1 SPTBN4 MYO3A

3.00e-031481184C0279702
DiseaseLiver diseases

TGM1 NFKB1 IL9R

3.04e-03721183C0023895
DiseaseLiver Dysfunction

TGM1 NFKB1 IL9R

3.04e-03721183C0086565
DiseaseNonsyndromic genetic hearing loss

MYH9 MYO3A GJB3

3.54e-03761183cv:C5680182
DiseaseSensorineural Hearing Loss (disorder)

MYH9 GJB3

3.80e-03231182C0018784
DiseasePR interval

MYH11 ZNF184 OBSCN DNPH1 DYSF MYO3A SYNE3

3.82e-034951187EFO_0004462

Protein segments in the cluster

PeptideGeneStartEntry
QVWDYEEGEVEALLD

DNPH1

141

O43598
EDDQNWYKAELRGVE

GRAPL

31

Q8TC17
EDDQNWYKAELRGVE

GRAP

31

Q13588
YHWLESNVDAEEREV

CHRNA2

401

Q15822
YEDVERQWKGHDLNE

CALU

106

O43852
EQNWRQHREAYEEDE

DNAJA4

371

Q8WW22
RIGNWNEDVYLEEEL

CFAP161

11

Q6P656
RDNNIFSEWDGILDY

GKN3P

51

P0CG01
EDDGWEIGYLDRTSQ

ASZ1

21

Q8WWH4
EEARSKAEEWGVQYV

RALB

141

P11234
QVRWYKDGLEVEASD

OBSL1

1111

O75147
EYQWIGLNDRTIEGD

BCAN

741

Q96GW7
EEDRVRNEYEESQWT

NPHS1

1106

O60500
NVVGYDLDLDRWEDI

KLHL34

591

Q8N239
YEALAEQNRKDAEAW

KRT28

266

Q7Z3Y7
QIDEDIQLDGYDIWE

ARSJ

391

Q5FYB0
DDRWINDVEDSYGQQ

ATP1A1

891

P05023
SDEDRYQNGAERRWE

CWC22

866

Q9HCG8
QWDVDTIYHAEDNRE

CARMIL3

176

Q8ND23
GDQESRWKQYLEDER

CUEDC1

221

Q9NWM3
GQYLQLQELECDWEE

EVPL

1711

Q92817
QLEYSREGLVWEDID

MYO10

471

Q9HD67
AWVLNNGQYEEDVEE

RASAL2

961

Q9UJF2
SIYDEGVDEWNIARL

KDM4C

141

Q9H3R0
EGADAEDVIYVNWLN

DPP3

531

Q9NY33
NRQEDWEYIIGFCDQ

GGA3

21

Q9NZ52
VPTELNDIWRYNEEE

KLHL40

576

Q2TBA0
ILEQEEYQREGIEWN

MYH9

486

P35579
YLNRGDRWIQDEIEF

PADI2

341

Q9Y2J8
DRWIQDEIEFGYIEA

PADI2

346

Q9Y2J8
SEYIIRGDDEEWNEV

NAT10

961

Q9H0A0
GEDYDQWAVDDIIIL

RELN

1206

P78509
ICQLDYWDESAEENG

HERC5

551

Q9UII4
YWDESAEENGNVQAL

HERC5

556

Q9UII4
QVEGDDRAFEVWQER

OBSCN

5961

Q5VST9
EYEGEAILWQRSAAE

PPP1R16B

361

Q96T49
AENEQEQEGWYRALT

IRS2

126

Q9Y4H2
EQEGWYRALTDLVSE

IRS2

131

Q9Y4H2
REVEYWDQRYQGAAD

EEF1AKMT4-ECE2

21

P0DPD8
GVDQLRDDNLETYWQ

ANAPC10

41

Q9UM13
NAEWVYQGAIRQIDD

APOB

4111

P04114
DLWERLYVEAKDQNG

CCPG1

446

Q9ULG6
QEEYEAWSQRGDIIQ

CARD14

861

Q9BXL6
EEFEEVIEDWYRNHQ

CNPY3

171

Q9BT09
KENFIGRQWEISDDY

CRYBA1

131

P05813
RDGREWEIVNQDNHY

DBH

426

P09172
RLDWEGNEHNRSYEE

BRWD1

51

Q9NSI6
SGWDVRDVNALVEEY

BTBD7

91

Q9P203
DADQWEENCAEVYGG

FGA

791

P02671
WEVYQRLGLEDDIVD

FGD2

301

Q7Z6J4
WDREVADVLVDGYNV

CLPB

601

Q9H078
RYNAVTGEWLDDEVL

EEF2K

116

O00418
EYLEQFVGDQEAWHE

EMC2

146

Q15006
DWLVEVGEEYKLQNE

CCNA2

216

P20248
QEWLAAVGDDYAAVV

CERCAM

81

Q5T4B2
YVVAAERVWGDEQKD

GJB3

36

O75712
RQRYWLGEEQEDAVQ

CROCCP3

101

Q8IVE0
YILFDGDVDALWVEN

DNAH10

2186

Q8IVF4
VIDEAQNFRTEDGDW

SLFN13

666

Q68D06
QGDEDQDYDYLRDWG

CDH15

756

P55291
TDLNRAVDEQGWEYS

DYSF

1001

O75923
QEEYQREGIEWNFID

MYH10

496

P35580
AVWDNGIDDAYFLEA

PRIMPOL

511

Q96LW4
RGQEFVWDYVILDEA

ERCC6L

216

Q2NKX8
RNDNSWGDLETYLEE

PIDD1

416

Q9HB75
AAWRERYEDSQQEEA

NUMA1

811

Q14980
LLERDVDINIYDWNG

RFXANK

176

O14593
NEDRETWVDADLYCQ

REG1A

51

P05451
GGIWEDEDARNFYEN

UPF2

456

Q9HAU5
YQEEDLNCVRERWSD

KIF13A

1086

Q9H1H9
DRDEQFYWIIEALGI

EPRS1

401

P07814
INDADWELLGELDYQ

URM1

71

Q9BTM9
VNEYRFAWVEADGVN

ATP6V1H

211

Q9UI12
AIILEDGQELDSWYV

RAPGEF6

306

Q8TEU7
DWQRVIEYHRENDEP

TEX14

986

Q8IWB6
KEYVNEEWARGEVRG

SH3D19

601

Q5HYK7
EHEEYQAGVDEFQLW

SYNE3

221

Q6ZMZ3
EEVYENQGRDTRGAW

FER1L5

856

A0AVI2
RSEEYEAEGQLRFWN

NIN

151

Q8N4C6
DNEDLVYGRWEDNII

TAF1

471

P21675
WNYRDEADVLEVDQG

GANAB

401

Q14697
EAAGEIDVAELQEWY

GUCA1B

11

Q9UMX6
VQWDIRSGEIVQEYD

CDC40

401

O60508
ANNIAYEDVVGGEDW

SCG2

236

P13521
RLNDDWAYGNDLDAR

STRIP1

746

Q5VSL9
VIDEAQNFRTEDGDW

SLFN11

666

Q7Z7L1
LYDIWNGGIDEEDIR

SETD1B

1681

Q9UPS6
DNVREDLYEAADKWV

PTGES2

301

Q9H7Z7
DRSWEEIIGNTDYAI

WDR17

696

Q8IZU2
QNLWRDQREEELGEY

SUPT5H

126

O00267
LEDDVVEEERYTGQW

IL9R

231

Q01113
WRKGEDEYANVDAIV

SUPT16H

21

Q9Y5B9
REVEYWDQRYQGAAD

EEF1AKMT4

21

P0DPD7
AQQRSWALYEDEGVI

NCKIPSD

396

Q9NZQ3
YDGRWEIEELKENQV

CLGN

91

O14967
NWEVDVAAQLGEYLE

NCAPH2

21

Q6IBW4
YDHQREQELREWIEG

CNN1

26

P51911
GYEDWLRHNSDNEVN

ATP11B

106

Q9Y2G3
QEEYQREGIEWNFID

MYH11

496

P35749
GLQFLLWYDEGEERN

TRBV5-8

61

A0A5A2
DYEFQWQEDERNGHE

ZNF761

96

Q86XN6
AENEEEAADVWYNLG

TTC8

416

Q8TAM2
DRWVEEQFDLAQYEE

TIAM1

1481

Q13009
LVNIYDLSDEDAGWR

MINDY4

116

Q4G0A6
WDEQERDAYADRVFD

PYROXD2

471

Q8N2H3
LGRLWFSVEYEQEAE

SYT15B

201

X6R8R1
QEEWECLDAVQRDLY

ZNF546

71

Q86UE3
ESQVEEWYREVGELQ

SPTBN4

1456

Q9H254
EWYREVGELQAQTAA

SPTBN4

1461

Q9H254
EDEIYNVYDQAWRGG

SNW1

426

Q13573
DHSYNVEQIWRDIED

TTLL6

296

Q8N841
QYDEALNKQDWVDGE

PRKDC

2971

P78527
EIQEWYEEHAREQEQ

TPCN1

776

Q9ULQ1
EWERLEADQRGLYQE

ZNF316

171

A6NFI3
YFSQEEWGLLDEAQR

ZNF416

36

Q9BWM5
DGWEEWYQNNQDELE

ZNF26

86

P17031
YFSQEEWGHLDEAQR

ZNF548

16

Q8NEK5
EDWRQEYVLNESGRI

TGM1

261

P22735
WDYIEGQDETLENVN

ARHGAP21

496

Q5T5U3
SAGLIDDNDLYRWEV

UBE2G1

26

P62253
AAGSLEEQWYLEIVD

ZNF512

151

Q96ME7
SNLDEDYQREGSNWL

TMEM266

66

Q2M3C6
LESWEYEGSLERQQA

ZNF184

141

Q99676
WYDEEARERQAAQCP

TRIM56

156

Q9BRZ2
AWIADVDEIQNGDHY

KDM5C

1031

P41229
AWEQNEYLNEDVDAR

MYO3A

751

Q8NEV4
SDDDRVIWAEQQYEK

PCSK1

91

P29120
QIRFYEEEENGGVWE

NFKB1

281

P19838