Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aldehyde dehydrogenase (NAD+) activity	ALDH1L1 ALDH3B1 ALDH3B2	5.00e-05	15	98	3	GO:0004029
GeneOntologyMolecularFunction	aldehyde dehydrogenase (NADP+) activity	ALDH1L1 ALDH3B1	7.13e-05	3	98	2	GO:0033721
GeneOntologyMolecularFunction	aldehyde dehydrogenase [NAD(P)+] activity	ALDH1L1 ALDH3B1 ALDH3B2	7.42e-05	17	98	3	GO:0004030
GeneOntologyMolecularFunction	3-chloroallyl aldehyde dehydrogenase activity	ALDH3B1 ALDH3B2	4.93e-04	7	98	2	GO:0004028
Domain	PHR	BTBD6 BTBD1 BTBD3	1.23e-06	5	94	3	PF08005
Domain	PHR	BTBD6 BTBD1 BTBD3	1.23e-06	5	94	3	IPR012983
Domain	BACK	BTBD6 BTBD1 KBTBD2 BTBD3 KLHL31	1.27e-05	60	94	5	SM00875
Domain	BACK	BTBD6 BTBD1 KBTBD2 BTBD3 KLHL31	1.38e-05	61	94	5	PF07707
Domain	BACK	BTBD6 BTBD1 KBTBD2 BTBD3 KLHL31	1.38e-05	61	94	5	IPR011705
Domain	ConA-like_dom	TRIM46 NBEAL1 BSPRY CNTNAP1 BTN3A3 EYS CNTNAP5 WDFY3	1.47e-05	219	94	8	IPR013320
Domain	LYZL1/LYZL2	LYZL1 LYZL2	2.51e-05	2	94	2	IPR030057
Domain	BTB	BTBD6 ZBTB4 BTBD1 KBTBD2 BTBD3 KLHL31	5.21e-05	131	94	6	PF00651
Domain	Ald_DH_CS_GLU	ALDH1L1 ALDH3B1 ALDH3B2	6.59e-05	16	94	3	IPR029510
Domain	Ald_DH_CS_CYS	ALDH1L1 ALDH3B1 ALDH3B2	7.98e-05	17	94	3	IPR016160
Domain	ALDEHYDE_DEHYDR_GLU	ALDH1L1 ALDH3B1 ALDH3B2	9.54e-05	18	94	3	PS00687
Domain	ALDEHYDE_DEHYDR_CYS	ALDH1L1 ALDH3B1 ALDH3B2	9.54e-05	18	94	3	PS00070
Domain	Ald_DH_C	ALDH1L1 ALDH3B1 ALDH3B2	1.13e-04	19	94	3	IPR016163
Domain	Ald_DH_N	ALDH1L1 ALDH3B1 ALDH3B2	1.13e-04	19	94	3	IPR016162
Domain	Ald_DH/histidinol_DH	ALDH1L1 ALDH3B1 ALDH3B2	1.13e-04	19	94	3	IPR016161
Domain	-	ALDH1L1 ALDH3B1 ALDH3B2	1.13e-04	19	94	3	3.40.605.10
Domain	Aldedh	ALDH1L1 ALDH3B1 ALDH3B2	1.13e-04	19	94	3	PF00171
Domain	Aldehyde_DH_dom	ALDH1L1 ALDH3B1 ALDH3B2	1.13e-04	19	94	3	IPR015590
Domain	-	ALDH1L1 ALDH3B1 ALDH3B2	1.13e-04	19	94	3	3.40.309.10
Domain	-	NBEAL1 CNTNAP1 EYS CNTNAP5 WDFY3	1.18e-04	95	94	5	2.60.120.200
Domain	Aldehyde_DH_NAD(P)	ALDH3B1 ALDH3B2	1.49e-04	4	94	2	IPR012394
Domain	BTB	BTBD6 ZBTB4 BTBD1 KBTBD2 BTBD3 KLHL31	1.57e-04	160	94	6	PS50097
Domain	DUF4704	NBEAL1 WDFY3	2.48e-04	5	94	2	IPR031570
Domain	DUF4704	NBEAL1 WDFY3	2.48e-04	5	94	2	PF15787
Domain	BTB	BTBD6 ZBTB4 BTBD1 KBTBD2 BTBD3 KLHL31	2.98e-04	180	94	6	SM00225
Domain	BTB/POZ_dom	BTBD6 ZBTB4 BTBD1 KBTBD2 BTBD3 KLHL31	3.45e-04	185	94	6	IPR000210
Domain	PH_BEACH	NBEAL1 WDFY3	3.71e-04	6	94	2	PF14844
Domain	SKP1/BTB/POZ	BTBD6 ZBTB4 BTBD1 KBTBD2 BTBD3 KLHL31	3.86e-04	189	94	6	IPR011333
Domain	Glyco_hydro_22_lys	LYZL1 LYZL2	5.18e-04	7	94	2	IPR000974
Domain	Glyco_hydro_22_CS	LYZL1 LYZL2	5.18e-04	7	94	2	IPR019799
Domain	PH-BEACH_dom	NBEAL1 WDFY3	6.88e-04	8	94	2	IPR023362
Domain	-	NBEAL1 WDFY3	6.88e-04	8	94	2	2.30.29.40
Domain	Glyco_hydro_22	LYZL1 LYZL2	6.88e-04	8	94	2	IPR001916
Domain	LACTALBUMIN_LYSOZYME_2	LYZL1 LYZL2	6.88e-04	8	94	2	PS51348
Domain	Lys	LYZL1 LYZL2	6.88e-04	8	94	2	PF00062
Domain	PH_BEACH	NBEAL1 WDFY3	6.88e-04	8	94	2	PS51783
Domain	LACTALBUMIN_LYSOZYME_1	LYZL1 LYZL2	6.88e-04	8	94	2	PS00128
Domain	LYZ1	LYZL1 LYZL2	6.88e-04	8	94	2	SM00263
Domain	BEACH_dom	NBEAL1 WDFY3	8.82e-04	9	94	2	IPR000409
Domain	BEACH	NBEAL1 WDFY3	8.82e-04	9	94	2	PS50197
Domain	Beach	NBEAL1 WDFY3	8.82e-04	9	94	2	PF02138
Domain	-	NBEAL1 WDFY3	8.82e-04	9	94	2	1.10.1540.10
Domain	Beach	NBEAL1 WDFY3	8.82e-04	9	94	2	SM01026
Domain	LAM_G_DOMAIN	CNTNAP1 EYS CNTNAP5	9.17e-04	38	94	3	PS50025
Domain	Laminin_G_2	CNTNAP1 EYS CNTNAP5	1.07e-03	40	94	3	PF02210
Domain	Lysozyme-like_dom	LYZL1 LYZL2	1.10e-03	10	94	2	IPR023346
Domain	LamG	CNTNAP1 EYS CNTNAP5	1.41e-03	44	94	3	SM00282
Domain	Calpain_domain_III	CAPN10 CAPN13	1.89e-03	13	94	2	IPR022682
Domain	Calpain_III	CAPN10 CAPN13	1.89e-03	13	94	2	PF01067
Domain	Calpain_cysteine_protease	CAPN10 CAPN13	2.19e-03	14	94	2	IPR022684
Domain	CysPc	CAPN10 CAPN13	2.52e-03	15	94	2	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN10 CAPN13	2.52e-03	15	94	2	IPR001300
Domain	Peptidase_C2	CAPN10 CAPN13	2.52e-03	15	94	2	PF00648
Domain	CALPAIN_CAT	CAPN10 CAPN13	2.52e-03	15	94	2	PS50203
Domain	Laminin_G	CNTNAP1 EYS CNTNAP5	3.12e-03	58	94	3	IPR001791
Domain	aa-tRNA-synth_I_CS	MARS1 QARS1	3.64e-03	18	94	2	IPR001412
Domain	NA_NEUROTRAN_SYMP_2	SLC6A1 SLC6A4	3.64e-03	18	94	2	PS00754
Domain	SNF	SLC6A1 SLC6A4	4.05e-03	19	94	2	PF00209
Domain	NA_NEUROTRAN_SYMP_1	SLC6A1 SLC6A4	4.05e-03	19	94	2	PS00610
Domain	NA_NEUROTRAN_SYMP_3	SLC6A1 SLC6A4	4.05e-03	19	94	2	PS50267
Domain	Na/ntran_symport	SLC6A1 SLC6A4	4.05e-03	19	94	2	IPR000175
Domain	AA_TRNA_LIGASE_I	MARS1 QARS1	4.05e-03	19	94	2	PS00178
Domain	FA58C	CNTNAP1 CNTNAP5	4.95e-03	21	94	2	SM00231
Domain	FA58C_3	CNTNAP1 CNTNAP5	4.95e-03	21	94	2	PS50022
Domain	FA58C_1	CNTNAP1 CNTNAP5	4.95e-03	21	94	2	PS01285
Domain	FA58C_2	CNTNAP1 CNTNAP5	4.95e-03	21	94	2	PS01286
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BTBD3 XPO6 WDFY3 TRIM37 ZNF292	5.72e-06	87	101	5	12465718
Pubmed	Molecular and Functional Relevance of NaV1.8-Induced Atrial Arrhythmogenic Triggers in a Human SCN10A Knock-Out Stem Cell Model.	SLC6A4 SCN10A	8.35e-06	2	101	2	37373335
Pubmed	GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake.	ERP44 SLC6A4	8.35e-06	2	101	2	25512553
Pubmed	Human aldehyde dehydrogenase genes, ALDH7 and ALDH8: genomic organization and gene structure comparison.	ALDH3B1 ALDH3B2	8.35e-06	2	101	2	9161417
Pubmed	HPA axis reactivity: a mechanism underlying the associations among 5-HTTLPR, stress, and depression.	SLC6A1 SLC6A4	8.35e-06	2	101	2	18005940
Pubmed	C-LTMRs mediate wet dog shakes via the spinoparabrachial pathway.	GPR83 SCN10A TRPM8	2.23e-05	19	101	3	38915692
Pubmed	Testosterone-androgen receptor: The steroid link inhibiting TRPM8-mediated cold sensitivity.	SCN10A TRPM8	2.50e-05	3	101	2	32277850
Pubmed	Cold sensing by NaV1.8-positive and NaV1.8-negative sensory neurons.	SCN10A TRPM8	4.99e-05	4	101	2	30755524
Pubmed	Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling.	SCN10A TRPM8	4.99e-05	4	101	2	22850668
Pubmed	Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification.	ALDH3B1 ALDH3B2	4.99e-05	4	101	2	25286108
Pubmed	Alteration of gastric functions and candidate genes associated with weight reduction in response to sibutramine.	SLC6A1 SLC6A4	8.30e-05	5	101	2	17544870
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CNTNAP1 ZBTB4 BTBD1 SLC4A3 TXNDC11 SLC6A1 FRY SBNO1 WDFY3 QARS1 WDR17 TRIM37 ZNF292	9.00e-05	1285	101	13	35914814
Pubmed	A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.	BTBD6 BTBD1 KBTBD2 BTBD3	1.24e-04	87	101	4	37495603
Pubmed	Lack of association between genetic polymorphisms affecting sympathetic activity and tilt-induced vasovagal syncope.	SLC6A4 ADRA1A	1.24e-04	6	101	2	20129829
Pubmed	Gene structure, chromosomal localization, and expression pattern of Capn12, a new member of the calpain large subunit gene family.	CAPN10 CAPN13	1.24e-04	6	101	2	10964513
Pubmed	Cortical RORβ is required for layer 4 transcriptional identity and barrel integrity.	PLXND1 SLC6A4	1.24e-04	6	101	2	32851975
Pubmed	An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.	SCN10A TRPM8	1.24e-04	6	101	2	23711479
Pubmed	The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2 are dispensable for fertility in mice.	LYZL1 LYZL2	1.24e-04	6	101	2	29563520
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	DNHD1 EEF1AKMT4-ECE2 ERP44 ESPNL LYZL1 TMEM161A EYS LCTL APH1A KAT14 ERVFRD-1	1.39e-04	985	101	11	12975309
Pubmed	Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver.	CYP3A43 CASR	2.31e-04	8	101	2	18794335
Pubmed	Heat shock protein 90 mediates protein-protein interactions between human aminoacyl-tRNA synthetases.	MARS1 QARS1	2.31e-04	8	101	2	10913161
Pubmed	Distribution of monocarboxylate transporters in the peripheral nervous system suggests putative roles in lactate shuttling and myelination.	CNTNAP1 SLC16A2	2.31e-04	8	101	2	25762662
Pubmed	ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest.	HEXD LRRC9 LCTL SBNO1 UBR3	2.33e-04	189	101	5	29449217
Pubmed	Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis.	MARS1 QARS1	2.97e-04	9	101	2	10791971
Pubmed	Anatomical and functional dichotomy of ocular itch and pain.	SCN10A TRPM8	2.97e-04	9	101	2	29988128
Pubmed	The human EPRS locus (formerly the QARS locus): a gene encoding a class I and a class II aminoacyl-tRNA synthetase.	MARS1 QARS1	3.70e-04	10	101	2	8188258
Pubmed	New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis.	SATB2 CASR	3.70e-04	10	101	2	22527485
Pubmed	The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex.	MARS1 QARS1	3.70e-04	10	101	2	16055448
Pubmed	The appended C-domain of human methionyl-tRNA synthetase has a tRNA-sequestering function.	MARS1 QARS1	3.70e-04	10	101	2	11714285
Pubmed	Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit.	MARS1 QARS1	3.70e-04	10	101	2	8052601
Pubmed	Divergent phenotypes in constitutive versus conditional mutant mouse models of Sifrim-Hitz-Weiss syndrome.	SATB2 ALDH1L1	3.70e-04	10	101	2	37738575
Pubmed	Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer.	MARS1 QARS1	3.70e-04	10	101	2	8078941
Pubmed	Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant.	MARS1 QARS1	3.70e-04	10	101	2	9278442
Pubmed	Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells.	MARS1 QARS1	4.51e-04	11	101	2	19289464
Pubmed	Expression of human aspartyl-tRNA synthetase in Escherichia coli. Functional analysis of the N-terminal putative amphiphilic helix.	MARS1 QARS1	4.51e-04	11	101	2	8449960
Pubmed	Lrig1 and Lrig3 cooperate to control Ret receptor signaling, sensory axonal growth and epidermal innervation.	SCN10A TRPM8	4.51e-04	11	101	2	34338291
Pubmed	Dissection of the structural organization of the aminoacyl-tRNA synthetase complex.	MARS1 QARS1	4.51e-04	11	101	2	19131329
Pubmed	Smad anchor for receptor activation nuclear localization during development identifies Layers V and VI of the neocortex.	SATB2 WDFY3	5.41e-04	12	101	2	32037591
Pubmed	Novel CUL3 Variant Causing Familial Hyperkalemic Hypertension Impairs Regulation and Function of Ubiquitin Ligase Activity.	BTBD1 KBTBD2 BTBD3	6.21e-04	57	101	3	34878901
Pubmed	Etv4 regulates nociception by controlling peptidergic sensory neuron development and peripheral tissue innervation.	SCN10A TRPM8	6.38e-04	13	101	2	35904071
Pubmed	Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein.	MARS1 QARS1	6.38e-04	13	101	2	9878398
Pubmed	Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse.	SATB2 CNTNAP1	6.38e-04	13	101	2	36793543
Pubmed	Thalamocortical axons control the cytoarchitecture of neocortical layers by area-specific supply of VGF.	BTBD3 SLC6A4	6.38e-04	13	101	2	35289744
Pubmed	Neocortical neuronal production and maturation defects in the TcMAC21 mouse model of Down syndrome.	SATB2 ALDH1L1	6.38e-04	13	101	2	38025769
Pubmed	p38 is essential for the assembly and stability of macromolecular tRNA synthetase complex: implications for its physiological significance.	MARS1 QARS1	7.43e-04	14	101	2	12060739
Pubmed	Direct and indirect neurogenesis generate a mosaic of distinct glutamatergic projection neuron types in cerebral cortex.	SATB2 PLXND1	8.55e-04	15	101	2	37348506
Pubmed	In the developing cerebral cortex: axonogenesis, synapse formation, and synaptic plasticity are regulated by SATB2 target genes.	SATB2 PLXND1	8.55e-04	15	101	2	36028553
Pubmed	The familial dysautonomia disease gene IKBKAP is required in the developing and adult mouse central nervous system.	PKD2L1 SV2A	8.55e-04	15	101	2	28167615
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SATB2 PLXND1 KBTBD2 ANKRD50 CAPN10 PCNX1 CACNA1G	9.09e-04	529	101	7	14621295
Pubmed	Effects of perfluorooctanoic acid (PFOA) on expression of peroxisome proliferator-activated receptors (PPAR) and nuclear receptor-regulated genes in fetal and postnatal CD-1 mouse tissues.	CYP3A43 CPT1B	9.76e-04	16	101	2	22154759
Pubmed	A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex.	SATB2 ALDH1L1	9.76e-04	16	101	2	38713624
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	CNTNAP1 SLC4A3 SLC6A1 TMEM161A ADRA1A APH1A SV2A SLC25A28	9.85e-04	697	101	8	28298427
Pubmed	Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation.	SATB2 SV2A	1.10e-03	17	101	2	27476503
Pubmed	Brain-specific Wt1 deletion leads to depressive-like behaviors in mice via the recruitment of Tet2 to modulate Epo expression.	SATB2 ALDH1L1	1.10e-03	17	101	2	32393787
Pubmed	Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.	DNHD1 RNF31	1.10e-03	17	101	2	12693554
Pubmed	The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse.	SATB2 ALDH1L1	1.24e-03	18	101	2	34935271
Pubmed	Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex.	MAP2K4 SATB2	1.24e-03	18	101	2	22090513
Pubmed	Variation in catechol-O-methyltransferase is associated with duloxetine response in a clinical trial for major depressive disorder.	SLC6A4 ADRA1A	1.38e-03	19	101	2	19095219
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	NBEAL1 EHD4 TMEM161A SV2A WDFY3	1.49e-03	285	101	5	34369648
Pubmed	Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation.	SCN10A TRPM8	1.53e-03	20	101	2	33789102
Pubmed	The repertoire of solute carriers of family 6: identification of new human and rodent genes.	SLC6A1 SLC6A4	1.69e-03	21	101	2	16125675
Pubmed	ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons.	SCN10A TRPM8	1.69e-03	21	101	2	25369838
Pubmed	BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development.	SATB2 ALDH1L1	1.69e-03	21	101	2	38101413
Pubmed	Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development.	SATB2 ALDH1L1	2.03e-03	23	101	2	36103829
Pubmed	Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems.	ALDH1L1 ALDH3B1	2.03e-03	23	101	2	18971422
Pubmed	Sidekick 2 directs formation of a retinal circuit that detects differential motion.	SATB2 SV2A	2.03e-03	23	101	2	26287463
Pubmed	Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.	SCN10A TRPM8	2.03e-03	23	101	2	16446141
Pubmed	A germline-specific class of small RNAs binds mammalian Piwi proteins.	BTBD6 ZBTB4 SPINT2 SBNO1 WDFY3 SLC25A28	2.04e-03	450	101	6	16751776
Pubmed	The DNA sequence and analysis of human chromosome 6.	PRICKLE4 CALHM5 RAB44 KLHL31 BTN3A3 EYS ERVFRD-1	2.29e-03	622	101	7	14574404
Pubmed	A microarray minisequencing system for pharmacogenetic profiling of antihypertensive drug response.	CASR ADRA1A	2.40e-03	25	101	2	12544508
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	CYP3A43 ALDH1L1 ALDH3B1 ALDH3B2	2.47e-03	193	101	4	19343046
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	TRIM46 RNF31 UBR3	2.71e-03	95	101	3	29643511
Pubmed	Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe.	SLC6A4 CORIN	2.80e-03	27	101	2	27789623
Pubmed	Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation.	BTBD6 CEP97	2.80e-03	27	101	2	30404837
Pubmed	An introduction to TRP channels.	PKD2L1 TRPM8	2.80e-03	27	101	2	16460286
Cytoband	2p22-p21	MEMO1 CAPN13	1.33e-04	8	101	2	2p22-p21
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	BTBD6 ZBTB4 BTBD1 KBTBD2 BTBD3 KLHL31	1.02e-05	134	67	6	861
GeneFamily	Aldehyde dehydrogenases	ALDH1L1 ALDH3B1 ALDH3B2	4.52e-05	19	67	3	398
GeneFamily	Lysozymes, c-type	LYZL1 LYZL2	4.79e-04	9	67	2	1174
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 WDFY3	4.79e-04	9	67	2	1230
GeneFamily	C2 domain containing\|Calpains	CAPN10 CAPN13	1.38e-03	15	67	2	975
GeneFamily	Aminoacyl tRNA synthetases, Class I	MARS1 QARS1	2.22e-03	19	67	2	131
GeneFamily	Transient receptor potential cation channels	PKD2L1 TRPM8	4.81e-03	28	67	2	249
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HSERT	TRIM46 MAP2K4 BTBD6 BTBD1 SLC4A3 SLC6A1 SLC6A4 FRY SPINT2 FNDC10 CACNA1G	1.34e-06	450	101	11	M39072
Coexpression	GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN	USP18 RNF31 EHD4 BTN3A3 PCNX1 SLC25A28 TMEM140	1.27e-05	200	101	7	M8967
Coexpression	GSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_DN	USP18 RNF31 TCIRG1 EHD4 BTN3A3 SLC25A28 TMEM140	1.27e-05	200	101	7	M9570
Computational	Peptide and AA transporters.	SLC6A1 SLC6A4 SLC16A2	8.77e-05	18	53	3	MODULE_368
Computational	Genes in the cancer module 162.	SLC6A1 SLC6A4 SLC16A2	1.04e-04	19	53	3	MODULE_162
Computational	Genes in the cancer module 218.	SLC6A1 SLC6A4 SLC16A2	1.22e-04	20	53	3	MODULE_218
Disease	YKL40 measurement, cerebrospinal fluid biomarker measurement	EYS CNTNAP5	9.98e-05	5	94	2	EFO_0004869, EFO_0006794
Disease	autism spectrum disorder (implicated_via_orthology)	CNTNAP1 SLC6A4 CNTNAP5 WDFY3 NAA16	1.29e-04	152	94	5	DOID:0060041 (implicated_via_orthology)
Disease	Sjogren-Larsson syndrome (implicated_via_orthology)	ALDH3B1 ALDH3B2	1.49e-04	6	94	2	DOID:14501 (implicated_via_orthology)
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP1 CNTNAP5	2.78e-04	8	94	2	DOID:0060308 (implicated_via_orthology)
Disease	Ventricular Fibrillation	SLC4A3 SCN10A	2.78e-04	8	94	2	C0042510
Disease	oropharynx cancer	SATB2 CAPN13 WDFY3	4.30e-04	46	94	3	EFO_1001931
Disease	Shortened QT interval	SLC4A3 SCN10A	5.42e-04	11	94	2	C0151879
Disease	glycochenodeoxycholate glucuronide (1) measurement	CACNA1G SLC25A28	7.65e-04	13	94	2	EFO_0800474
Disease	diverticular disease	ZBTB4 AFMID SPINT2 NOTUM SLC25A28	9.66e-04	236	94	5	EFO_0009959
Disease	Headache, HbA1c measurement	NBEAL1 PLXND1	2.03e-03	21	94	2	EFO_0004541, HP_0002315
Disease	chronic widespread pain	MAP2K4 CASR	2.43e-03	23	94	2	EFO_0010099

Protein segments in the cluster

Peptide	Gene	Start	Entry
FCRAQDLEYLTGRVW	SLC4A3	781	P48751
LRCYGDRNSWNTISF	CNTNAP1	776	P78357
ERFEWRYCVLGCENF	BTN3A3	376	O00478
SNQWRYRGRCDSIQF	BTBD6	401	Q96KE9
ESVECIRYNFRGFRW	CASR	56	P41180
FEVLGYWAFGRVFCN	ADRA1A	86	P35348
QTVANRVAWFRYFNA	ALDH3B1	226	P43353
RVAWFRYFNAGQTCV	ALDH3B1	231	P43353
NQWRYRGRCDSIQFA	BTBD3	386	Q9Y2F9
ADQEYRGSFTCRIWQ	CAPN10	101	Q9HC96
QYAGIFRFRFWQCGQ	CAPN13	121	Q6MZZ7
SLLQGKQFYCREWVF	ANKRD50	16	Q9ULJ7
AACWIDVLGRSFLYN	DNHD1	1636	Q96M86
TVANRVAWFCYFNAG	ALDH3B2	146	P48448
FRQRTYRIWAFGIAA	SLC16A2	316	P36021
IVQFYGALFREGDCW	MAP2K4	161	P45985
QYLLFDFRIWNRGDF	NBEAL1	1001	Q6ZS30
CFVLQLWDTAGQERY	RAB44	881	Q7Z6P3
GFRDWQCQAYSVRTS	ADAMTS19	691	Q8TE59
FHRQSWEFYQTLCQG	AFMID	251	Q63HM1
KGREWFARYVSAQRC	KIAA0513	131	O60268
LILSRFCAWDFRTYG	LRRC9	411	Q6ZRR7
DICGYINRSFAFWKE	ESPNL	981	Q6ZVH7
VSNFCRYDPRFNTWI	KLHL31	386	Q9H511
DYGIFQINSFAWCRR	LYZL1	71	Q6UWQ5
DYGIFQINSFAWCRR	LYZL2	71	Q7Z4W2
DSQEYRYLCFLRWAG	EYS	546	Q5T1H1
FLECCIYWVGFAFRN	NNAT	26	Q16517
VVFFDACERRRYWAL	APH1A	176	Q96BI3
QGFFRDIWVFQFCLV	PCNX1	1026	Q96RV3
FERRGCVHGNLTFWY	PLXND1	1051	Q9Y4D7
LEAAERYLQFCLGWF	LCTL	276	Q6UWM7
WFQTECISAYQRLGR	NAA16	486	Q6N069
GRQGYFRWKEDICAF	KAT14	141	Q9H8E8
YRRCGFPQLWAASAF	HEXD	241	Q8WVB3
QTAFRTVNCFYWFDA	KBTBD2	341	Q8IY47
CVRAVWQNEGAGAFY	SLC25A28	211	Q96A46
RYGQCWVFAGVFNTF	F13A1	311	P00488
GYDFCQVLQWFAERV	EHD4	171	Q9H223
NYTFSDWQNFVGRRR	GPR83	46	Q9NYM4
ERRYCAFNNWGSVEE	GIMAP5	181	Q96F15
LLFLEGGWYCFNREN	NOTUM	121	Q6P988
VYGSALCNAQRWLNF	NPC1L1	191	Q9UHC9
YGVFAARAGEQRCWH	PRICKLE4	96	Q2TBC4
EDFYQFSCGGWIRRN	EEF1AKMT4-ECE2	236	P0DPD8
NLRKAYGRNESWLCF	APOBEC3F	206	Q8IUX4
CRLGHNAFSWVFSRY	BSPRY	316	Q5W0U4
LFYLRGLWNFDRECN	CYP3A43	51	Q9HB55
CYLGDTWNRLDFFIV	CACNA1G	146	O43497
GFFLNNRSWRLFTGC	CALHM5	66	Q8N5C1
AATKLQACWRGFYAR	CEP97	561	Q8IW35
FALNCSWRGAYTRFP	FNDC10	106	F2Z333
CINRFQQVESRWGYS	BTBD1	331	Q9H0C5
NYSWPDFLRCSQFRN	CORIN	231	Q9Y5Q5
ADVALVNFYADWCRF	ERP44	46	Q9BS26
IFWIQERFYESGNRA	MBLAC2	16	Q68D91
QINLFNWAIDRCYTG	FRY	1216	Q5TBA9
GQFWSAHQRFFKYLC	SBNO1	591	A3KN83
LRCYGDRRFWNAVSF	CNTNAP5	781	Q8WYK1
GNCYNRWFDKSFTLI	CPT1B	446	Q92523
VSSDFCHWGQRFRYS	MEMO1	186	Q9Y316
SCNPRSVYENFRLWQ	NUTM2D	251	Q5VT03
QARRSSYFWLCNALD	QARS1	461	P47897
ECWGYNRFFRLDLLA	TRIM37	371	O94972
DTQRTFAYDQIFLCW	TRIM46	436	Q7Z4K8
FECVSISWFYGVNRF	SLC6A1	466	P30531
QGKSYWNRLRFLDTC	PPP4R4	576	Q6NUP7
QEAGADDLFFCYRWL	TBC1D25	396	Q3MII6
RIGFYNFCLWNEDTS	TMEM140	46	Q9NV12
SFARWLLCNGSLFRY	TMEM161A	26	Q9NX61
RNFHCWDYRRFVATQ	RABGGTA	141	Q92696
DKIREFCQRYFGWNR	ERCC5	956	P28715
FCQRYFGWNRTKTDE	ERCC5	961	P28715
YANVSATKCQEFGRW	SATB2	211	Q9UPW6
YFGTRGQFRCNLEWH	SLC26A10	426	Q8NG04
AEWYFQDGRAVLAAC	WDR17	951	Q8IZU2
FLFCRVRYSQLHGWN	SNX31	31	Q8N9S9
LRECGHGRFQWTLYF	SV2A	156	Q7L0J3
SIQTFRYFAGWCDKI	ALDH1L1	526	O75891
FSVRDYWRGFFAATC	CLCNKA	231	P51800
FLWCAQCSFGFIYER	RNF31	796	Q96EP0
SRFFDAWCQQRLALF	ZSWIM9	31	Q86XI8
LDDFRIWQGYNFLCD	WDFY3	301	Q8IZQ1
SQSFFWYRQDCRKEP	TRAV12-1	51	A0A0B4J245
STRNFWFRPADYNQC	ERVFRD-1	201	P60508
NLFAGKFWRCINYTD	SCN10A	1301	Q9Y5Y9
FPRWYFDVERNSCNN	SPINT2	146	O43291
ERGFISARFRNWQAY	ZNF292	526	O60281
DQRVRFYPVAFFCCW	TMEM116	136	Q8NCL8
YIFSWFNVKEGRTRC	XKR4	441	Q5GH76
GERRYQCIFCWETFV	ZBTB4	361	Q9P1Z0
LIRYVSNWDFFIVGC	PKD2L1	341	Q9P0L9
FFYAPWCGQSIAARA	TXNDC11	131	Q6PKC3
VYIRNAVDGKWFCFN	USP41	321	Q3LFD5
FLSARDFGERWGNYC	ZMYM6	501	O95789
GLVWTANFVAYRCRT	UBR3	121	Q6ZT12
QFRFERWNCTLEGRY	WNT9A	96	O14904
ADAESFRQRFRWFCY	ZNF483	46	Q8TF39
FRQRFRWFCYSEVAG	ZNF483	51	Q8TF39
VYIRNAVDGKWFCFN	USP18	321	Q9UMW8
FVLFCDEVRQWYVNG	TRPM8	776	Q7Z2W7
NNFAQQIGAWRFCLY	XPO6	36	Q96QU8
AVSWFYGITQFCRDV	SLC6A4	511	P31645
TEWNSRCVLFTYFQG	VGLL1	21	Q99990
CRYFFLLSGWEQDDL	MARS1	66	P56192
AAQNEIWQTFFRGRY	TCIRG1	431	Q13488