Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncomplement component C3b binding

CFHR1 CFHR2 CR1

6.77e-0612643GO:0001851
GeneOntologyMolecularFunctionRNA transmembrane transporter activity

SIDT2 SIDT1

3.03e-053642GO:0051033
GeneOntologyMolecularFunctionnucleic acid transmembrane transporter activity

SIDT2 SIDT1

3.03e-053642GO:0051032
GeneOntologyMolecularFunctionX11-like protein binding

CLSTN3 CLSTN2

3.03e-053642GO:0042988
GeneOntologyMolecularFunctionopsonin binding

CFHR1 CFHR2 CR1

6.87e-0525643GO:0001846
GeneOntologyMolecularFunctionprotein-lysine 6-oxidase activity

LOX LOXL1

1.01e-045642GO:0004720
GeneOntologyMolecularFunctioncomplement binding

CFHR1 CFHR2 CR1

1.46e-0432643GO:0001848
GeneOntologyMolecularFunctionproteoglycan binding

SLIT1 SEMA5A CTSS

5.86e-0451643GO:0043394
GeneOntologyMolecularFunctionmetalloendopeptidase activity

MMEL1 ADAMTS7 ADAMTS17 IDE

5.97e-04120644GO:0004222
GeneOntologyMolecularFunctionaxon guidance receptor activity

ROBO1 SEMA5A

7.71e-0413642GO:0008046
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

LOX LOXL1

1.18e-0316642GO:0016641
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRM PTPRT

1.33e-0317642GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRM PTPRT

1.33e-0317642GO:0019198
GeneOntologyMolecularFunctionDNA replication origin binding

MCM10 DDX11

1.50e-0318642GO:0003688
GeneOntologyMolecularFunctiongrowth factor binding

A2M IGF2R GLG1 FGFR2

1.58e-03156644GO:0019838
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors

LOX LOXL1

1.85e-0320642GO:0016638
GeneOntologyMolecularFunctionendopeptidase activity

CNTNAP5 MMEL1 ADAMTS7 ADAMTS17 IDE CTSS

2.52e-03430646GO:0004175
GeneOntologyBiologicalProcessneuron projection extension

CLSTN3 NRCAM SLIT1 TRPV2 ROBO1 SEMA5A ITGA4 UNC13A

2.46e-07207648GO:1990138
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

CLSTN3 NRCAM SLIT1 TRPV2 ROBO1 SEMA5A FGFR2 ITGA4 UNC13A

3.43e-07299649GO:0060560
GeneOntologyBiologicalProcesscomplement activation

A2M CFHR1 CFHR2 IGHE CR1

2.54e-0670645GO:0006956
GeneOntologyBiologicalProcessdevelopmental cell growth

CLSTN3 NRCAM SLIT1 TRPV2 ROBO1 SEMA5A ITGA4 UNC13A

4.08e-06301648GO:0048588
GeneOntologyBiologicalProcessnegative regulation of synapse assembly

CLSTN3 SLIT1 ROBO1

1.26e-0515643GO:0051964
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

CLSTN3 NRCAM PTPRM ROBO1 CLSTN2 PTPRT

2.48e-05187646GO:0007156
GeneOntologyBiologicalProcessnegative regulation of synapse organization

CLSTN3 SLIT1 ROBO1

3.64e-0521643GO:1905809
GeneOntologyBiologicalProcesssynapse organization

CLSTN3 NRCAM NCAN SLIT1 ROBO1 CLSTN2 FGFR2 CSMD2 UNC13A PTPRT

4.58e-056856410GO:0050808
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

CLSTN3 NRCAM PTPRM ROBO1 CLSTN2 ITGA4 PTPRT

5.13e-05313647GO:0098742
GeneOntologyBiologicalProcessretinal ganglion cell axon guidance

NRCAM PTPRM SLIT1

5.50e-0524643GO:0031290
GeneOntologyBiologicalProcessregulation of protein binding

CFHR1 CFHR2 LOX IDE ITGA4 DDX11

7.50e-05228646GO:0043393
GeneOntologyBiologicalProcesspeptidyl-lysine oxidation

LOX LOXL1

9.42e-055642GO:0018057
GeneOntologyBiologicalProcesscell-cell adhesion

BTN2A2 CLSTN3 NRCAM PTPRM MYO10 CD28 ROBO1 CLSTN2 ITGA4 CR1 PTPRT NCK2

1.02e-0410776412GO:0098609
GeneOntologyBiologicalProcesscell growth

CLSTN3 NRCAM SLIT1 TRPV2 KDM2B ROBO1 SEMA5A ITGA4 UNC13A

1.27e-04625649GO:0016049
GeneOntologyBiologicalProcessextracellular matrix organization

OLFML2A ADAMTS7 LOX LOXL1 ADAMTS17 SEMA5A CTSS

1.64e-04377647GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

OLFML2A ADAMTS7 LOX LOXL1 ADAMTS17 SEMA5A CTSS

1.66e-04378647GO:0043062
GeneOntologyBiologicalProcessneuron projection morphogenesis

CLSTN3 NRCAM PTPRM SLIT1 TRPV2 ROBO1 SEMA5A FGFR2 ITGA4 UNC13A

1.69e-048026410GO:0048812
GeneOntologyBiologicalProcessexternal encapsulating structure organization

OLFML2A ADAMTS7 LOX LOXL1 ADAMTS17 SEMA5A CTSS

1.69e-04379647GO:0045229
GeneOntologyBiologicalProcesscell junction organization

CLSTN3 NRCAM NCAN SLIT1 ROBO1 ACTN4 CLSTN2 FGFR2 CSMD2 UNC13A PTPRT

1.84e-049746411GO:0034330
GeneOntologyBiologicalProcessregulation of synapse organization

CLSTN3 NRCAM NCAN SLIT1 ROBO1 CLSTN2 PTPRT

1.92e-04387647GO:0050807
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

CLSTN3 NRCAM PTPRM SLIT1 TRPV2 ROBO1 SEMA5A FGFR2 ITGA4 UNC13A

2.00e-048196410GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

CLSTN3 NRCAM PTPRM SLIT1 TRPV2 ROBO1 SEMA5A FGFR2 ITGA4 UNC13A

2.14e-048266410GO:0048858
GeneOntologyBiologicalProcessregulation of synapse structure or activity

CLSTN3 NRCAM NCAN SLIT1 ROBO1 CLSTN2 PTPRT

2.18e-04395647GO:0050803
GeneOntologyBiologicalProcesscell morphogenesis

CLSTN3 SIDT2 NRCAM PTPRM MYO10 SLIT1 TRPV2 ROBO1 SEMA5A FGFR2 ITGA4 UNC13A

2.68e-0411946412GO:0000902
GeneOntologyBiologicalProcessnegative regulation of cell junction assembly

CLSTN3 SLIT1 ROBO1

2.79e-0441643GO:1901889
GeneOntologyBiologicalProcessregulation of axon extension

NRCAM SLIT1 TRPV2 SEMA5A

3.07e-04104644GO:0030516
GeneOntologyBiologicalProcessnegative regulation of protein binding

CFHR1 CFHR2 ITGA4 DDX11

3.30e-04106644GO:0032091
GeneOntologyBiologicalProcessaxonogenesis

NRCAM PTPRM SLIT1 TRPV2 ROBO1 SEMA5A FGFR2 ITGA4

3.51e-04566648GO:0007409
GeneOntologyBiologicalProcesssynapse assembly

CLSTN3 NRCAM SLIT1 ROBO1 CLSTN2 CSMD2

3.83e-04308646GO:0007416
GeneOntologyBiologicalProcesscytolysis by host of symbiont cells

CFHR1 CFHR2

4.20e-0410642GO:0051838
GeneOntologyBiologicalProcesstangential migration from the subventricular zone to the olfactory bulb

SLIT1 ROBO1

4.20e-0410642GO:0022028
GeneOntologyBiologicalProcessregulation of regulatory T cell differentiation

BTN2A2 CD28 CR1

4.74e-0449643GO:0045589
GeneOntologyBiologicalProcesshumoral immune response

A2M CFHR1 CFHR2 IGHE CD28 CR1

4.76e-04321646GO:0006959
GeneOntologyBiologicalProcessnegative regulation of axon extension involved in axon guidance

SLIT1 SEMA5A

5.12e-0411642GO:0048843
GeneOntologyBiologicalProcessolfactory bulb interneuron development

SLIT1 ROBO1

5.12e-0411642GO:0021891
GeneOntologyBiologicalProcessnegative chemotaxis

SLIT1 ROBO1 SEMA5A

5.34e-0451643GO:0050919
GeneOntologyBiologicalProcessregulation of extent of cell growth

NRCAM SLIT1 TRPV2 SEMA5A

5.63e-04122644GO:0061387
GeneOntologyBiologicalProcessregulation of anatomical structure size

NRCAM PTPRM SLIT1 TRPV2 KCNMB1 SEMA5A ITGA4 NCK2

6.27e-04618648GO:0090066
GeneOntologyBiologicalProcessregulatory T cell differentiation

BTN2A2 CD28 CR1

6.31e-0454643GO:0045066
GeneOntologyBiologicalProcessnegative regulation of chemotaxis

SLIT1 ROBO1 SEMA5A

6.31e-0454643GO:0050922
GeneOntologyBiologicalProcessactivation of immune response

A2M CFHR1 CFHR2 BTN2A2 IGHE CD28 CR1 CTSS

6.61e-04623648GO:0002253
GeneOntologyBiologicalProcessaxon development

NRCAM PTPRM SLIT1 TRPV2 ROBO1 SEMA5A FGFR2 ITGA4

8.03e-04642648GO:0061564
GeneOntologyBiologicalProcessneuron recognition

NRCAM ROBO1 SEMA5A

8.18e-0459643GO:0008038
GeneOntologyBiologicalProcessaxon extension

NRCAM SLIT1 TRPV2 SEMA5A

8.23e-04135644GO:0048675
GeneOntologyBiologicalProcessprotein oxidation

LOX LOXL1

8.42e-0414642GO:0018158
GeneOntologyBiologicalProcessnegative regulation of complement activation

A2M CR1

8.42e-0414642GO:0045916
GeneOntologyBiologicalProcessregulation of cell growth

CLSTN3 NRCAM SLIT1 TRPV2 KDM2B SEMA5A UNC13A

1.10e-03519647GO:0001558
GeneOntologyCellularComponentcell surface

BTN2A2 CLSTN3 IGF2R NRCAM ADAMTS7 CD28 RTP2 TRPV2 ROBO1 CLSTN2 FGFR2 IDE ITGA4 CR1 IL3RA CTSS PTPRT

3.16e-0811116517GO:0009986
GeneOntologyCellularComponentextracellular matrix

A2M OLFML2A COL6A3 ADAMTS7 GLG1 LOX LOXL1 NCAN ADAMTS17 FGFR2 MUC5AC CTSS

7.25e-076566512GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

A2M OLFML2A COL6A3 ADAMTS7 GLG1 LOX LOXL1 NCAN ADAMTS17 FGFR2 MUC5AC CTSS

7.49e-076586512GO:0030312
GeneOntologyCellularComponentpostsynaptic density membrane

CLSTN3 NRCAM CLSTN2 CSMD2 PTPRT

1.29e-04157655GO:0098839
GeneOntologyCellularComponentcollagen-containing extracellular matrix

A2M COL6A3 LOX LOXL1 NCAN ADAMTS17 FGFR2 CTSS

2.30e-04530658GO:0062023
GeneOntologyCellularComponentpostsynaptic specialization membrane

CLSTN3 NRCAM CLSTN2 CSMD2 PTPRT

4.05e-04201655GO:0099634
GeneOntologyCellularComponentexternal side of plasma membrane

BTN2A2 NRCAM CD28 IDE ITGA4 CR1 IL3RA

1.12e-03519657GO:0009897
DomainSushi

CFHR1 CFHR2 NCAN CSMD2 CR1

9.25e-0752645PF00084
DomainCCP

CFHR1 CFHR2 NCAN CSMD2 CR1

1.12e-0654645SM00032
DomainSUSHI

CFHR1 CFHR2 NCAN CSMD2 CR1

1.35e-0656645PS50923
DomainSushi_SCR_CCP_dom

CFHR1 CFHR2 NCAN CSMD2 CR1

1.47e-0657645IPR000436
DomainIg-like_fold

COL6A3 BTN2A2 NRCAM PTPRM IGHE CD28 NCAN ROBO1 LSAMP FGFR2 IL3RA PTPRT

4.19e-067066412IPR013783
DomainIG_LIKE

BTN2A2 NRCAM PTPRM IGHE CD28 NCAN ROBO1 LSAMP FGFR2 PTPRT

6.10e-064916410PS50835
DomainIg-like_dom

BTN2A2 NRCAM PTPRM IGHE CD28 NCAN ROBO1 LSAMP FGFR2 PTPRT

7.54e-065036410IPR007110
DomainConA-like_dom

BTN2A2 CLSTN3 CNTNAP5 PTPRM SLIT1 CLSTN2 PTPRT

9.76e-06219647IPR013320
DomainSID1_TM_fam

SIDT2 SIDT1

1.16e-052642IPR025958
DomainSID-1_RNA_chan

SIDT2 SIDT1

1.16e-052642PF13965
Domain-

COL6A3 BTN2A2 NRCAM PTPRM CD28 NCAN ROBO1 LSAMP FGFR2 IL3RA PTPRT

1.39e-0566364112.60.40.10
DomainCalsyntenin

CLSTN3 CLSTN2

3.46e-053642IPR026914
DomainFN3_dom

COL6A3 NRCAM PTPRM ROBO1 IL3RA PTPRT

7.98e-05209646IPR003961
DomainIG

BTN2A2 NRCAM PTPRM NCAN ROBO1 LSAMP FGFR2 PTPRT

9.15e-05421648SM00409
DomainIg_sub

BTN2A2 NRCAM PTPRM NCAN ROBO1 LSAMP FGFR2 PTPRT

9.15e-05421648IPR003599
DomainLysyl_oxidase

LOX LOXL1

1.15e-045642IPR001695
DomainLYSYL_OXIDASE

LOX LOXL1

1.15e-045642PS00926
DomainLysyl_oxidase_CS

LOX LOXL1

1.15e-045642IPR019828
DomainLysyl_oxidase

LOX LOXL1

1.15e-045642PF01186
Domain-

CLSTN3 CNTNAP5 SLIT1 CLSTN2

3.16e-04956442.60.120.200
DomainFN3

COL6A3 NRCAM PTPRM ROBO1 PTPRT

4.29e-04185645SM00060
DomainFN3

COL6A3 NRCAM PTPRM ROBO1 PTPRT

5.98e-04199645PS50853
DomainTSP_1

ADAMTS7 ADAMTS17 SEMA5A

1.32e-0363643PF00090
DomainMAM_1

PTPRM PTPRT

1.34e-0316642PS00740
DomainTSP1

ADAMTS7 ADAMTS17 SEMA5A

1.44e-0365643SM00209
DomainTSP1_rpt

ADAMTS7 ADAMTS17 SEMA5A

1.44e-0365643IPR000884
DomainTSP1

ADAMTS7 ADAMTS17 SEMA5A

1.44e-0365643PS50092
DomainMAM

PTPRM PTPRT

1.52e-0317642SM00137
DomainMAM

PTPRM PTPRT

1.71e-0318642PF00629
DomainMAM_dom

PTPRM PTPRT

1.71e-0318642IPR000998
DomainMAM_2

PTPRM PTPRT

1.71e-0318642PS50060
DomainCTCK_1

SLIT1 MUC5AC

1.71e-0318642PS01185
DomainPLAC

ADAMTS7 ADAMTS17

1.90e-0319642PS50900
DomainPLAC

ADAMTS7 ADAMTS17

1.90e-0319642IPR010909
DomainIGv

BTN2A2 CD28 ROBO1

2.17e-0375643SM00406
Domainfn3

NRCAM PTPRM ROBO1 PTPRT

2.31e-03162644PF00041
DomainCT

SLIT1 MUC5AC

2.55e-0322642SM00041
DomainMetalloPept_cat_dom

MMEL1 ADAMTS7 ADAMTS17

2.71e-0381643IPR024079
Domain-

MMEL1 ADAMTS7 ADAMTS17

2.71e-03816433.40.390.10
DomainADAM_spacer1

ADAMTS7 ADAMTS17

2.79e-0323642IPR010294
DomainADAM_spacer1

ADAMTS7 ADAMTS17

2.79e-0323642PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS7 ADAMTS17

3.04e-0324642IPR013273
DomainTYR_PHOSPHATASE_1

MTMR12 PTPRM PTPRT

3.21e-0386643PS00383
DomainCys_knot_C

SLIT1 MUC5AC

3.30e-0325642IPR006207
DomainCTCK_2

SLIT1 MUC5AC

3.30e-0325642PS01225
DomainTYR_PHOSPHATASE_2

MTMR12 PTPRM PTPRT

3.31e-0387643PS50056
DomainPHD

KDM2B G2E3 SP140

3.53e-0389643SM00249
DomainZnf_PHD

KDM2B G2E3 SP140

3.76e-0391643IPR001965
DomainHECT

G2E3 HERC4

3.84e-0327642PF00632
DomainHECTc

G2E3 HERC4

3.84e-0327642SM00119
DomainHECT_dom

G2E3 HERC4

3.84e-0327642IPR000569
DomainHECT

G2E3 HERC4

3.84e-0327642PS50237
DomainIg_I-set

NRCAM ROBO1 LSAMP FGFR2

4.10e-03190644IPR013098
DomainI-set

NRCAM ROBO1 LSAMP FGFR2

4.10e-03190644PF07679
DomainZF_PHD_2

KDM2B G2E3 SP140

4.24e-0395643PS50016
DomainZF_PHD_1

KDM2B G2E3 SP140

4.37e-0396643PS01359
DomainZINC_PROTEASE

MMEL1 ADAMTS7 ADAMTS17

4.63e-0398643PS00142
DomainProt-tyrosine_phosphatase-like

MTMR12 PTPRM PTPRT

4.76e-0399643IPR029021
DomainIg_V-set

BTN2A2 CD28 NCAN ROBO1

4.83e-03199644IPR013106
DomainPTPc

PTPRM PTPRT

6.76e-0336642SM00194
DomainLAM_G_DOMAIN

CNTNAP5 SLIT1

7.51e-0338642PS50025
DomainPeptidase_M12B_N

ADAMTS7 ADAMTS17

7.89e-0339642IPR002870
DomainPep_M12B_propep

ADAMTS7 ADAMTS17

7.89e-0339642PF01562
DomainTYR_PHOSPHATASE_PTP

PTPRM PTPRT

7.89e-0339642PS50055
DomainDISINTEGRIN_1

ADAMTS7 ADAMTS17

8.29e-0340642PS00427
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS7 NCAN ADAMTS17 SEMA5A MUC5AC ALG13

1.52e-05143536M27275
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL6A3 LOX LOXL1 CTSS

3.61e-0550534MM14796
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL6A3 LOX LOXL1 CTSS

7.93e-0561534M27103
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS7 ADAMTS17 SEMA5A MUC5AC

1.21e-0468534M27303
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

A2M COL6A3 LOX LOXL1 NCAN ITGA4 CTSS

1.23e-04300537M610
PathwayKEGG_CELL_ADHESION_MOLECULES_CAMS

NRCAM PTPRM CD28 GLG1 ITGA4

1.38e-04133535M16476
PathwayREACTOME_COLLAGEN_FORMATION

COL6A3 LOX LOXL1 CTSS

1.87e-0476534MM14573
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR

CFHR1 CFHR2

2.06e-046532M47880
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS7 NCAN ADAMTS17 SEMA5A MUC5AC ALG13

3.35e-04250536M27554
PathwayREACTOME_COLLAGEN_FORMATION

COL6A3 LOX LOXL1 CTSS

3.58e-0490534M631
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

A2M COL6A3 LOX LOXL1 ITGA4 CTSS

3.96e-04258536MM14572
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS7 ADAMTS17 SEMA5A

4.17e-0439533M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS7 ADAMTS17 SEMA5A

4.17e-0439533MM15165
PathwayREACTOME_NETRIN_1_SIGNALING

MYO10 SLIT1 ROBO1

5.96e-0444533M875
PathwayREACTOME_REGULATION_OF_COMMISSURAL_AXON_PATHFINDING_BY_SLIT_AND_ROBO

SLIT1 ROBO1

6.12e-0410532M27348
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS7 ADAMTS17 SEMA5A MUC5AC

7.40e-04109534MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS7 ADAMTS17 SEMA5A MUC5AC

7.92e-04111534M27416
PathwayREACTOME_ACTIVATION_OF_RAC1

ROBO1 NCK2

1.05e-0313532M6322
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

COL6A3 NRCAM MYO10 NCAN SLIT1 ROBO1 SEMA5A NCK2

1.28e-03575538M29853
PathwayKEGG_AXON_GUIDANCE

SLIT1 ROBO1 SEMA5A NCK2

1.39e-03129534M5539
Pubmed

The adaptor protein Nck2 mediates Slit1-induced changes in cortical neuron morphology.

SLIT1 ROBO1 NCK2

2.49e-08465321600986
Pubmed

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

MYO10 LOX LOXL1 FGFR2

2.81e-065265430389913
Pubmed

Deficiency of Mouse FHR-1 Homolog, FHR-E, Accelerates Sepsis, and Acute Kidney Injury Through Enhancing the LPS-Induced Alternative Complement Pathway.

CFHR1 CFHR2

3.44e-06265232636836
Pubmed

Comparative immunocytochemical localization of lysyl oxidase (LOX) and the lysyl oxidase-like (LOXL) proteins: changes in the expression of LOXL during development and growth of mouse tissues.

LOX LOXL1

3.44e-06265215609098
Pubmed

Inhibition of Lysyl Oxidase and Lysyl Oxidase-Like Enzymes Has Tumour-Promoting and Tumour-Suppressing Roles in Experimental Prostate Cancer.

LOX LOXL1

3.44e-06265226804196
Pubmed

Molecular cloning of a human serum protein structurally related to complement factor H.

CFHR1 CFHR2

3.44e-0626521711047
Pubmed

Crosstalk of lysyl oxidase-like 1 and lysyl oxidase prolongs their half-lives and regulates liver fibrosis through Notch signal.

LOX LOXL1

3.44e-06265238466882
Pubmed

Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases.

CFHR1 CFHR2

3.44e-06265233651882
Pubmed

A novel family of mammalian transmembrane proteins involved in cholesterol transport.

SIDT2 SIDT1

3.44e-06265228785058
Pubmed

A new gene with sequence and structural similarity to the gene encoding human lysyl oxidase.

LOX LOXL1

3.44e-0626527706256
Pubmed

Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell.

LOX LOXL1

3.44e-06265212577300
Pubmed

Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1.

SIDT2 SIDT1

3.44e-06265226067272
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

NRCAM PTPRM SLIT1 SEMA5A FGFR2 ITGA4

7.70e-0625165629031500
Pubmed

The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers.

LOX LOXL1

1.03e-05365216251195
Pubmed

Calsyntenin-3 interacts with the sodium-dependent vitamin C transporter-2 to regulate vitamin C uptake.

CLSTN3 CLSTN2

1.03e-05365234673103
Pubmed

The expression of lysyl-oxidase gene family members in myeloproliferative neoplasms.

LOX LOXL1

1.03e-05365223494965
Pubmed

The calsyntenins--a family of postsynaptic membrane proteins with distinct neuronal expression patterns.

CLSTN3 CLSTN2

1.03e-05365212498782
Pubmed

Elevated expression levels of lysyl oxidases protect against aortic aneurysm progression in Marfan syndrome.

LOX LOXL1

1.03e-05365225988230
Pubmed

Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in Pseudoexfoliation.

LOX LOXL1

1.03e-05365227116380
Pubmed

Serum FHR1 binding to necrotic-type cells activates monocytic inflammasome and marks necrotic sites in vasculopathies.

CFHR1 CFHR2

1.03e-05365231273197
Pubmed

A molecular mechanism for the heparan sulfate dependence of slit-robo signaling.

SLIT1 ROBO1

1.03e-05365217062560
Pubmed

ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling.

SLIT1 ROBO1

1.03e-05365230504844
Pubmed

ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis.

LOX LOXL1

1.03e-05365230890638
Pubmed

The copper dependent-lysyl oxidases contribute to the pathogenesis of pulmonary emphysema in chronic obstructive pulmonary disease patients.

LOX LOXL1

1.03e-05365228965583
Pubmed

C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation.

CFHR1 CFHR2

1.03e-05365223728178
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

SLIT1 ROBO1 SEMA5A

1.97e-052865318617019
Pubmed

Differential expression of the LOX family genes in human colorectal adenocarcinomas.

LOX LOXL1

2.06e-05465219724858
Pubmed

Atypical haemolytic-uraemic syndrome due to heterozygous mutations of CFH/CFHR1-3 and complement factor H 479.

CFHR1 CFHR2

2.06e-05465224333077
Pubmed

Upregulated copper transporters in hypoxia-induced pulmonary hypertension.

LOX LOXL1

2.06e-05465224614111
Pubmed

Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes.

BTN2A2 CD28

2.06e-05465223589618
Pubmed

Contralateral migration of oculomotor neurons is regulated by Slit/Robo signaling.

SLIT1 ROBO1

2.06e-05465227770832
Pubmed

Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin.

A2M ADAMTS7

2.06e-05465218485748
Pubmed

Lysyl oxidases: a novel multifunctional amine oxidase family.

LOX LOXL1

2.06e-05465211642359
Pubmed

The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance.

SLIT1 ROBO1

2.06e-05465210433822
Pubmed

Nuclear translocation of lysyl oxidase is promoted by interaction with transcription repressor p66β.

LOX LOXL1

2.06e-05465225118846
Pubmed

Expression patterns of Slit and Robo family members during vertebrate limb development.

SLIT1 ROBO1

2.06e-05465211472852
Pubmed

Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.

MYO10 ROBO1 CSMD2 PTPRT

2.52e-059065415033168
Pubmed

Slit and robo: expression patterns in lung development.

SLIT1 ROBO1

3.43e-05565212609596
Pubmed

Complement factor H and related proteins: an expanding family of complement-regulatory proteins?

CFHR1 CFHR2

3.43e-0556528172644
Pubmed

Factor H-related proteins determine complement-activating surfaces.

CFHR1 CFHR2

3.43e-05565225979655
Pubmed

The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.

SLIT1 ROBO1

3.43e-05565215084255
Pubmed

Identification and sequence analysis of four complement factor H-related transcripts in mouse liver.

CFHR1 CFHR2

3.43e-0556521689298
Pubmed

On the topographic targeting of basal vomeronasal axons through Slit-mediated chemorepulsion.

SLIT1 ROBO1

3.43e-05565212954717
Pubmed

Expression of fibroblast growth factor receptors in peri-implantation mouse embryos.

GLG1 FGFR2

3.43e-0556529771645
Pubmed

Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding.

SLIT1 ROBO1

3.43e-05565215207848
Pubmed

A radiation hybrid map of complement factor H and factor H-related genes.

CFHR1 CFHR2

3.43e-05565210380701
Pubmed

Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.

SLIT1 ROBO1

3.43e-05565225894826
Pubmed

Expression patterns of Slit and Robo family members in adult mouse spinal cord and peripheral nervous system.

SLIT1 ROBO1

3.43e-05565228234971
Pubmed

Common polymorphisms in human lysyl oxidase genes are not associated with the adolescent idiopathic scoliosis phenotype.

LOX LOXL1

3.43e-05565221740577
Pubmed

Slit1 is specifically expressed in the primary and secondary enamel knots during molar tooth cusp formation.

SLIT1 ROBO1

3.43e-05565211520671
Pubmed

Midbrain dopaminergic axons are guided longitudinally through the diencephalon by Slit/Robo signals.

SLIT1 ROBO1

3.43e-05565221118670
Pubmed

Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth.

SLIT1 ROBO1

3.43e-05565222772332
Pubmed

Slit proteins are not dominant chemorepellents for olfactory tract and spinal motor axons.

SLIT1 ROBO1

3.43e-05565211748139
Pubmed

A genomic atlas of mouse hypothalamic development.

NCAN ROBO1 SEMA5A LSAMP G2E3

4.20e-0520565520436479
Pubmed

Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism.

CLSTN3 CLSTN2

5.13e-05665212972431
Pubmed

SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium.

SLIT1 ROBO1

5.13e-05665218829537
Pubmed

Dimerization of complement factor H-related proteins modulates complement activation in vivo.

CFHR1 CFHR2

5.13e-05665223487775
Pubmed

Slit2 is a repellent for retinal ganglion cell axons.

SLIT1 ROBO1

5.13e-05665210864954
Pubmed

Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.

CFHR1 CFHR2

5.13e-05665227196323
Pubmed

Autocrine/juxtaparacrine regulation of axon fasciculation by Slit-Robo signaling.

SLIT1 ROBO1

5.13e-05665222306607
Pubmed

Slit/Robo-mediated chemorepulsion of vagal sensory axons in the fetal gut.

SLIT1 ROBO1

5.13e-05665223161783
Pubmed

Slit antagonizes netrin-1 attractive effects during the migration of inferior olivary neurons.

SLIT1 ROBO1

5.13e-05665212051827
Pubmed

The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons.

SLIT1 ROBO1

5.13e-05665218054781
Pubmed

Robo1 and robo2 control the development of the lateral olfactory tract.

SLIT1 ROBO1

5.13e-05665217360927
Pubmed

Slit2 and netrin 1 act synergistically as adhesive cues to generate tubular bi-layers during ductal morphogenesis.

SLIT1 ROBO1

5.13e-05665216439476
Pubmed

Pioneer longitudinal axons navigate using floor plate and Slit/Robo signals.

SLIT1 ROBO1

5.13e-05665218842816
Pubmed

Robo2 Receptor Gates the Anatomical Divergence of Neurons Derived From a Common Precursor Origin.

SLIT1 ROBO1

5.13e-05665234249921
Pubmed

Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications.

CFHR1 CFHR2

5.13e-05665217438673
Pubmed

Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age.

IGF2R NRCAM SLIT1

5.86e-054065336843585
Pubmed

Slit-Robo signals regulate pioneer axon pathfinding of the tract of the postoptic commissure in the mammalian forebrain.

SLIT1 ROBO1

7.18e-05765221688288
Pubmed

Slit molecules prevent entrance of trunk neural crest cells in developing gut.

SLIT1 ROBO1

7.18e-05765225490618
Pubmed

FLRT3 is a Robo1-interacting protein that determines Netrin-1 attraction in developing axons.

SLIT1 ROBO1

7.18e-05765224560577
Pubmed

Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation.

CLSTN3 CLSTN2

7.18e-05765215037614
Pubmed

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.

CLSTN3 PTPRM ROBO1 LSAMP CTSS PTPRT

7.40e-0537665624154525
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

SLIT1 ROBO1 SEMA5A FGFR2

9.37e-0512665416284245
Pubmed

Slit/Robo signaling mediates spatial positioning of spiral ganglion neurons during development of cochlear innervation.

SLIT1 ROBO1

9.56e-05865223884932
Pubmed

Robos and slits control the pathfinding and targeting of mouse olfactory sensory axons.

SLIT1 ROBO1

9.56e-05865218417704
Pubmed

Dual branch-promoting and branch-repelling actions of Slit/Robo signaling on peripheral and central branches of developing sensory axons.

SLIT1 ROBO1

9.56e-05865217581972
Pubmed

Conserved roles for Slit and Robo proteins in midline commissural axon guidance.

SLIT1 ROBO1

9.56e-05865215091338
Pubmed

Slit and robo expression in the developing mouse lung.

SLIT1 ROBO1

9.56e-05865215162513
Pubmed

Motor axons are guided to exit points in the spinal cord by Slit and Netrin signals.

SLIT1 ROBO1

9.56e-05865228986144
Pubmed

Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain.

SLIT1 ROBO1

9.56e-05865217392456
Pubmed

Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype.

LOX LOXL1

9.56e-05865219458888
Pubmed

Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neovascularization.

ROBO1 NCK2

9.56e-05865226659946
Pubmed

Multiple Slits regulate the development of midline glial populations and the corpus callosum.

SLIT1 ROBO1

9.56e-05865222349628
Pubmed

Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa.

LOX LOXL1

9.56e-05865227339457
Pubmed

PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments.

SLIT1 ROBO1

9.56e-05865225485759
Pubmed

Slit2 and Robo3 modulate the migration of GnRH-secreting neurons.

SLIT1 ROBO1

9.56e-05865222912413
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

A2M CFHR1 COL6A3 NRCAM PTPRM

1.22e-0425765516335952
Pubmed

Retinal ganglion cell axon guidance in the mouse optic chiasm: expression and function of robos and slits.

SLIT1 ROBO1

1.23e-04965210864955
Pubmed

Pioneer midbrain longitudinal axons navigate using a balance of Netrin attraction and Slit repulsion.

SLIT1 ROBO1

1.23e-04965225056828
Pubmed

Cooperative slit and netrin signaling in contralateralization of the mouse trigeminothalamic pathway.

SLIT1 ROBO1

1.23e-04965222806432
Pubmed

Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome.

CFHR1 CFHR2

1.23e-04965220059470
Pubmed

Localized LoxL3-Dependent Fibronectin Oxidation Regulates Myofiber Stretch and Integrin-Mediated Adhesion.

LOX LOXL1

1.23e-04965226954549
Pubmed

Collaborative and specialized functions of Robo1 and Robo2 in spinal commissural axon guidance.

SLIT1 ROBO1

1.23e-04965220631173
Pubmed

Nolz1 expression is required in dopaminergic axon guidance and striatal innervation.

PTPRM SLIT1 ROBO1

1.52e-045565332561725
Pubmed

Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development.

SLIT1 ROBO1

1.53e-041065221307234
Pubmed

TGF-beta1 induces the different expressions of lysyl oxidases and matrix metalloproteinases in anterior cruciate ligament and medial collateral ligament fibroblasts after mechanical injury.

LOX LOXL1

1.53e-041065223357697
Pubmed

Slit/Robo signals prevent spinal motor neuron emigration by organizing the spinal cord basement membrane.

SLIT1 ROBO1

1.53e-041065231356769
Pubmed

Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions.

A2M IGF2R IDE

1.61e-045665337059927
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CFHR1 CFHR2 NCAN CSMD2 CR1

4.95e-07575051179
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

NRCAM PTPRM ROBO1 LSAMP FGFR2

8.07e-05161505593
GeneFamilyComplement system|Sushi domain containing

CFHR1 CFHR2 CR1

1.33e-0436503492
GeneFamilyADAM metallopeptidase domain containing|CD molecules

IGF2R CD28 FGFR2 ITGA4 CR1 IL3RA

7.29e-04394506471
GeneFamilyFibronectin type III domain containing

NRCAM PTPRM ROBO1 PTPRT

9.91e-04160504555
GeneFamilyCadherin related

CLSTN3 CLSTN2

9.93e-041750224
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS7 ADAMTS17

1.24e-031950250
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRM PTPRT

1.52e-0321502813
GeneFamilyPHD finger proteins

KDM2B G2E3 SP140

1.97e-039050388
GeneFamilyAdenosine receptors|V-set domain containing

BTN2A2 CD28 NCAN

1.03e-02163503590
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

COL6A3 LOX LOXL1 ROBO1

1.60e-0635644M11788
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

COL6A3 LOX LOXL1 ROBO1

1.80e-0636644MM1212
CoexpressionGSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_UP

MTMR12 TRPV2 G2E3 IDE INTS8 DCAF4

8.97e-06198646M4283
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPERIC

A2M CFHR1 OLFML2A PTPRM SIDT1 TRPV2 KCNMB1 SEMA5A ITGA4 NCK2

2.14e-057956410M39050
CoexpressionNABA_ECM_REGULATORS

A2M ADAMTS7 LOX LOXL1 ADAMTS17 CTSS

2.54e-05238646M3468
CoexpressionNABA_ECM_REGULATORS

A2M ADAMTS7 LOX LOXL1 ADAMTS17 CTSS

2.79e-05242646MM17062
CoexpressionNABA_MATRISOME

A2M COL6A3 ADAMTS7 LOX LOXL1 NCAN SLIT1 ADAMTS17 SEMA5A MUC5AC CTSS

2.96e-0510086411MM17056
CoexpressionTERAMOTO_OPN_TARGETS_CLUSTER_6

ADAMTS7 SLIT1 ACTN4

3.47e-0526643M1202
CoexpressionTERAMOTO_OPN_TARGETS_CLUSTER_6

ADAMTS7 SLIT1 ACTN4

3.47e-0526643MM523
CoexpressionNABA_MATRISOME

A2M COL6A3 ADAMTS7 LOX LOXL1 NCAN SLIT1 ADAMTS17 SEMA5A MUC5AC CTSS

3.48e-0510266411M5889
CoexpressionURS_ADIPOCYTE_DIFFERENTIATION_DN

COL6A3 LOX LOXL1

5.94e-0531643M18395
CoexpressionBOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP

A2M CFHR2 OLFML2A MYO10 LOX ITGA4 CTSS

8.09e-05427647M17923
CoexpressionSWEET_LUNG_CANCER_KRAS_DN

CFHR1 CFHR2 LOX LOXL1 ROBO1 FGFR2 ARHGEF3

1.03e-04444647MM1051
CoexpressionONKEN_UVEAL_MELANOMA_UP

IGF2R PTPRM TRPV2 PUM3 ACTN4 IDE INTS8 CTSS ALG13

1.23e-04790649M12490
CoexpressionGSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN

DHRS3 CD28 SIDT1 INTS8 DDX11

1.24e-04198645M5419
CoexpressionGSE3982_BCELL_VS_TH1_UP

SIDT2 SIDT1 CR1 MUC5AC NCK2

1.27e-04199645M5551
CoexpressionGSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_UP

NRCAM CD28 SIDT1 NCK2 SP140

1.27e-04199645M4494
CoexpressionGSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_UP

DHRS3 TRPV2 KDM2B ACTN4 HERC4

1.30e-04200645M7742
CoexpressionGSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_UP

SIDT1 ARHGEF3 ITGA4 HERC4 CTSS

1.30e-04200645M7027
CoexpressionGSE17721_LPS_VS_POLYIC_16H_BMDC_UP

IGF2R DHRS3 GLG1 ARHGEF3 ITGA4

1.30e-04200645M3818
CoexpressionTRAVAGLINI_LUNG_PERICYTE_CELL

NRCAM MYO10 SEMA5A NCK2

1.76e-04114644M41678
CoexpressionSCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP

COL6A3 PTPRM LOX LOXL1 ROBO1 CTSS

2.19e-04352646M17471
CoexpressionKRAS.50_UP.V1_UP

A2M CFHR2 NRCAM

2.22e-0448643M2878
CoexpressionMURARO_PANCREAS_DUCTAL_CELL

A2M OLFML2A MTMR12 IGF2R DHRS3 PTPRM MYO10 ACTN4 FGFR2 CTSS NCK2

2.41e-0412766411M39173
CoexpressionWESTON_VEGFA_TARGETS_6HR

CFHR1 COL6A3 SEMA5A

2.51e-0450643M1521
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000

COL6A3 CLSTN3 NRCAM MYO10 LOXL1 NCAN ADAMTS17 NINL CLSTN2 FGFR2 MCM10 CTSS SP140

3.18e-069766113Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_k-means-cluster#5_top-relative-expression-ranked_1000

LOX SEMA5A G2E3 ITGA4

1.39e-0551614gudmap_developingGonad_P2_testes_1000_k5
CoexpressionAtlasgudmap_RNAseq_p2_CD2APMEISWT_2500_K4

CFHR2 COL6A3 DHRS3 MYO10 KCNMB1 SEMA5A ACTN4 FGFR2 ITGA4 CTSS SP140

2.43e-058426111gudmap_RNAseq_p2_CD2APMEISWT_2500_K4
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000

COL6A3 IGF2R NRCAM LOX SEMA5A LSAMP ITGA4 CTSS UNC13A PTPRT

4.19e-057346110gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_1000
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#5_top-relative-expression-ranked_200

LOX SEMA5A ITGA4

1.16e-0433613gudmap_developingGonad_P2_epididymis_200_k5
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

COL6A3 IGF2R NRCAM LOX LOXL1 ADAMTS17 ROBO1

1.13e-081886573f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M COL6A3 PTPRM LOX ROBO1 CLSTN2 CSMD2

1.13e-08188657997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

A2M COL6A3 PTPRM MYO10 ADAMTS17 ROBO1 LSAMP

1.30e-0819265762904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

A2M COL6A3 NRCAM MYO10 ADAMTS17 ROBO1 LSAMP

1.45e-08195657603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MMEL1 PTPRM ADAMTS17 ROBO1 FGFR2 SLC5A8

2.91e-071846567d41784eac0935e77d6bc701f20c693adf998730
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

A2M OLFML2A COL6A3 MYO10 ROBO1 LSAMP

3.21e-07187656e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM LOX LOXL1 SEMA5A LSAMP

3.41e-07189656a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM LOX ADAMTS17 ROBO1 SEMA5A

3.52e-0719065645df8fee00f8949937863159d7aa042e72748d9b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM LOX ROBO1 SEMA5A LSAMP

3.63e-07191656b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM LOX ROBO1 SEMA5A LSAMP

3.74e-071926566f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OLFML2A LOX LOXL1 KCNMB1 SEMA5A ITGA4

3.74e-0719265626d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM LOX ROBO1 SEMA5A LSAMP

3.74e-071926563d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OLFML2A LOX KCNMB1 SEMA5A CLSTN2 ITGA4

3.86e-0719365688916d9a7d831eb52848599917c04238f8f9812b
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OLFML2A LOX LOXL1 KCNMB1 SEMA5A ITGA4

3.86e-071936567fc3ab7261c88c1df71744bf5b17e8e46c4300e0
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M COL6A3 MYO10 ADAMTS17 ROBO1 LSAMP

3.86e-0719365699525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

A2M OLFML2A COL6A3 MYO10 ROBO1 LSAMP

3.86e-07193656acad568621ed677031797b8c2e34dafea798d681
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M COL6A3 MYO10 ADAMTS17 SEMA5A LSAMP

3.98e-07194656e93de9428c986b8943fc169258847c650cfab0e5
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM ADAMTS17 ROBO1 SEMA5A LSAMP

3.98e-0719465689b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A3 IGF2R NRCAM LOX LOXL1 ADAMTS17

4.22e-07196656617103f4a09e009fe96c28eb5e40505a4fd6dcf4
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A3 IGF2R NRCAM LOX LOXL1 ADAMTS17

4.22e-07196656db64ab27374f82553ee577aec056141170f3656f
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

A2M COL6A3 NRCAM ROBO1 LSAMP CSMD2

4.35e-07197656f1c8936986123a3151140c374fcd62d6705c530b
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

A2M OLFML2A COL6A3 TRPV2 SEMA5A ITGA4

4.48e-0719865672aad5b2dcd8b0bde58828fa4f8129fe6cb6a21d
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

A2M COL6A3 LOXL1 FGFR2 CTSS DDX11

4.62e-0719965656d72da6a5fab9cbb2975fe6f87a631debaba6a8
ToppCellBiopsy_Other_PF-Mesenchymal-Myofibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

A2M COL6A3 LOX LOXL1 ROBO1 LSAMP

4.75e-07200656e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCellFibroblast|World / shred by cell class for parenchyma

A2M COL6A3 LOX LOXL1 SLIT1 LSAMP

4.75e-07200656dec9ce1bc2571197003596f32e5f742ede72aa79
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESPN CD28 TRPV2 MCM10 UNC13A

4.07e-061636559c91415a56b12b3b2d15d253bb59db8bedf49ea2
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

COL6A3 LOX LOXL1 ADAMTS17 ARHGEF3

4.07e-06163655f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

A2M PTPRM ADAMTS7 ADAMTS17 SEMA5A

4.07e-06163655bba830a302919c8b33f914a8839877fc21dd28a0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

OLFML2A LOX SEMA5A ARHGEF3 CR1

4.99e-0617065560bbd738c12e64e483485586c30057304884f5a6
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

A2M COL6A3 NRCAM SEMA5A NCK2

5.44e-06173655fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL6A3 NRCAM LOX LOXL1 ADAMTS17

5.59e-061746553c47d069bd836599a8d40eae485c23d4d3487517
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M NRCAM MYO10 SEMA5A NCK2

6.24e-06178655185b44700f06ec58b3c09c80520502166c965fd6
ToppCellStriatum-Endothelial-MURAL|Striatum / BrainAtlas - Mouse McCarroll V32

OLFML2A LOX KCNMB1 ACTN4 ITGA4

6.42e-061796553d58babf44e47462c3d4129dd2e94a2339fd7ce0
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)|Striatum / BrainAtlas - Mouse McCarroll V32

OLFML2A LOX KCNMB1 ACTN4 ITGA4

6.42e-0617965599167ac678cae5c35b1d4f4a81b32000437c00c2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIDT1 ITGA4 CR1 CTSS SP140

6.59e-0618065565c069585737302a69b9a01476f4eb8b50cb2bfd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRM ADAMTS17 ROBO1 FGFR2 SLC5A8

6.77e-06181655af92b8b7f455210dab502ef6964f3a0162180759
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M COL6A3 MYO10 ROBO1 LSAMP

6.77e-061816559ede19228ba5c0668a9c06c915510b95585216ef
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 NRCAM LOX LOXL1 ADAMTS17

6.96e-06182655c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 NRCAM LOX LOXL1 ADAMTS17

6.96e-06182655dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD28 SIDT1 ITGA4 CTSS SP140

7.33e-061846555cf7447faaec99fc37dfa8e92ff72cc2c7c05951
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD28 SIDT1 ITGA4 CTSS SP140

7.33e-061846557126261a453c7e2f3f005016873b6adeb51e46f8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP5 PTPRM ADAMTS17 CSMD2 PTPRT

7.33e-06184655658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL6A3 BTN2A2 LSAMP DCAF4

7.53e-06185655e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL6A3 BTN2A2 LSAMP DCAF4

7.53e-061856559d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M PTPRM MYO10 SIDT1 IL3RA

7.53e-06185655602536a3308a848f106adcb0a83530997440c8f4
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BTN2A2 DHRS3 PTPRM ARHGEF3 ITGA4

7.93e-06187655ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MTMR12 SIDT2 IGF2R GLG1 INTS8

7.93e-06187655689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MTMR12 SIDT2 IGF2R GLG1 INTS8

7.93e-061876554527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIDT1 ITGA4 CR1 CTSS SP140

7.93e-061876558fa454dc4e6a3e8e2bb2ad803acc579e0d3f76da
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

A2M COL6A3 ADAMTS17 ROBO1 LSAMP

7.93e-0618765592d468dde81125d51daf7abd4703741abe1ab91c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M CLSTN3 PTPRM MYO10 IL3RA

7.93e-061876550ef82111b9049cc7ee78d64d240e1f10ab14d6b6
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

CD28 SIDT1 ITGA4 NCK2 SP140

7.93e-06187655f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIDT1 ITGA4 CR1 CTSS SP140

7.93e-06187655edad646d5eb1d70b768dc21fe02ef5265214e8e6
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LOX SEMA5A ACTN4 ARHGEF3 CR1

7.93e-0618765524c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

A2M COL6A3 NRCAM ROBO1 LSAMP

7.93e-06187655bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL6A3 NRCAM MYO10 SEMA5A NCK2

7.93e-06187655a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OLFML2A DHRS3 SEMA5A FGFR2 SLC5A8

8.14e-06188655842982de2197770f999a70083ed9fca40ac22d79
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OLFML2A DHRS3 SEMA5A FGFR2 SLC5A8

8.14e-06188655a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCellFibroblast-A|World / shred on cell class and cell subclass (v4)

COL6A3 NRCAM LOX LOXL1 ADAMTS17

8.14e-061886556740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCellP07-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

OLFML2A LOX LOXL1 SEMA5A ITGA4

8.14e-061886556ec22b79b19d57ea187f312907819dc2d01f3efe
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM LOX ADAMTS17 SEMA5A

8.35e-06189655e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellfacs-Skin-nan-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 LOX LOXL1 LSAMP IL3RA

8.35e-0618965529287525120be2953b76881ba3cfc4379c265e7a
ToppCellfacs-Skin-nan-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 LOX LOXL1 LSAMP IL3RA

8.35e-061896557150dad9a92a715487c2d8130fa01b752ea69663
ToppCellCOVID-19-T_cells-CD8+_T_cells|COVID-19 / group, cell type (main and fine annotations)

CD28 SIDT1 ITGA4 NCK2 SP140

8.35e-061896552c018d6120f65f0b2704b483bc9da1c0984872e3
ToppCellfacs-Skin-nan-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 LOX LOXL1 LSAMP IL3RA

8.35e-061896556e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

OLFML2A IGF2R TRPV2 ITGA4 NCK2

8.35e-061896559c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

OLFML2A COL6A3 MYO10 SLIT1 LSAMP

8.35e-06189655203c80030df08ae112f9ae4043709f455d87ce89
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

COL6A3 NRCAM MYO10 SEMA5A NCK2

8.35e-06189655d7ed96add29f219183c802895fbff519b627f635
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM MYO10 SEMA5A LSAMP

8.35e-061896552a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

COL6A3 IGF2R LOX ADAMTS17 ROBO1

8.35e-061896550c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL6A3 DHRS3 LSAMP CLSTN2

8.57e-061906552306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL6A3 NRCAM MYO10 SEMA5A NCK2

8.57e-061906554eb92aef1ee868f4537483d19014d947b7684612
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD28 SIDT1 ITGA4 NCK2 SP140

8.57e-06190655b772a5d281fe016f259ddda80d6f33d949dcac2b
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OLFML2A LOX LOXL1 KCNMB1 SEMA5A

8.57e-061906557df63e5e0dd395676f4fc18cad0d8b2428390943
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL6A3 DHRS3 LSAMP CLSTN2

8.57e-061906551f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL6A3 NRCAM MYO10 SEMA5A NCK2

8.57e-061906557be4341e2909101d756f14031c21e705eb45e69a
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OLFML2A LOX LOXL1 KCNMB1 SEMA5A

8.57e-06190655140aca04c044cd7a93f81ff1631b00b5216d2cb1
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM LOX LOXL1 SEMA5A

8.57e-06190655d60395739458d7f47a3350ade751fe3819500320
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL6A3 DHRS3 LSAMP CLSTN2

8.79e-06191655a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

COL6A3 IGF2R NRCAM LOX ADAMTS17

8.79e-061916553379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL6A3 NRCAM MYO10 ADAMTS17 LSAMP

8.79e-0619165508720998aa55131d7377c4c67c4c935865bd7d79
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD28 SIDT1 ITGA4 NCK2 SP140

8.79e-061916551a2d5fec2bea96da2154b0aed252f1bb35102f6e
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CD28 SIDT1 ITGA4 NCK2 SP140

8.79e-06191655c7be771543089fc94e5c62fd22f745189642aec3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD28 SIDT1 ITGA4 NCK2 SP140

8.79e-06191655326b4541069efedc8ab409f85bb11f77346dda90
ToppCellCOVID-19-T_cells|COVID-19 / group, cell type (main and fine annotations)

CD28 SIDT1 ITGA4 NCK2 SP140

8.79e-061916557f64add931b64b8d35836fa6bee9ebab593844d3
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

A2M COL6A3 ADAMTS17 ROBO1 LSAMP

8.79e-061916556688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL6A3 DHRS3 LSAMP CLSTN2

9.01e-061926559093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A3 NRCAM LOX LOXL1 ADAMTS17

9.01e-0619265525492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL6A3 DHRS3 LSAMP CLSTN2

9.01e-061926559ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM LOX ADAMTS17 SEMA5A

9.01e-06192655f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

A2M COL6A3 ADAMTS17 ROBO1 LSAMP

9.01e-0619265599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM LOX SEMA5A LSAMP

9.01e-06192655dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A3 NRCAM LOX LOXL1 ADAMTS17

9.01e-06192655de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM LOX ADAMTS17 SEMA5A

9.01e-061926554e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIDT2 GLG1 LOXL1 SEMA5A FGFR2

9.01e-061926550dc1f46e40346ed0b286e53b106a812441575100
ToppCellNS-moderate-d_0-4-Lymphoid|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CD28 TRPV2 ITGA4 MCM10 SP140

9.01e-06192655905217dcfc843d3469e9e71bd33707863b14cc82
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 NRCAM LOX SEMA5A LSAMP

9.01e-06192655deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LOX SEMA5A ACTN4 ARHGEF3 CR1

9.24e-061936553eaa0461618582a1754400624350d269d24e750a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M CFHR1 COL6A3 LOX LOXL1

9.24e-06193655dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A3 NRCAM LOX LOXL1 ADAMTS17

9.24e-061936554c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
DrugZ-Gly-phe-NH2

A2M GLG1 IDE

5.94e-0613643CID000096819
DrugBacitracin

A2M IDE

7.78e-062642DB00626
Drugdesmosine

COL6A3 LOX LOXL1 IDE

1.50e-0553644CID000025435
Drugchondroitin sulfate

A2M COL6A3 ADAMTS7 NCAN SEMA5A CLSTN2 ITGA4 DDX11

2.00e-05413648CID000024766
DrugTubocurarine chloride pentahydrate (+) [6989-98-6]; Up 200; 5.2uM; MCF7; HT_HG-U133A

BTN2A2 CLSTN3 SIDT2 CD28 FGFR2 CTSS

2.03e-051996465449_UP
DrugLinuron

IGF2R NRCAM SLIT1 ROBO1 FGFR2

3.04e-05128645ctd:D008044
Drugenzacamene

IGF2R NRCAM SLIT1 ROBO1 FGFR2

3.15e-05129645ctd:C038939
DrugVitamin K 3

A2M SIDT2 IGF2R PTPRM MYO10 GLG1 LOX KDM2B ROBO1 PUM3 G2E3 FGFR2 ITGA4

3.67e-0512496413ctd:D024483
Diseasemultiple sclerosis

ESPN IGF2R MMEL1 CD28 SIDT1 CLSTN2 ARHGEF3 CTSS SP140

5.25e-06594649MONDO_0005301
Diseasegalectin-4 measurement

ACTN4 ARHGEF3

2.77e-054642EFO_0020398
Diseasecomplement factor H-related protein 2 measurement

CFHR1 CFHR2 DDX11

3.42e-0529643EFO_0600055
Diseasedescending aortic diameter

COL6A3 ADAMTS7 LOXL1 ACTN4

4.09e-0588644EFO_0021788
Diseasespermidine measurement

CNTNAP5 ARHGEF3

4.61e-055642EFO_0021802
DiseaseAcute Confusional Senile Dementia

A2M IGF2R IDE CR1

6.49e-0599644C0546126
DiseaseAlzheimer's Disease, Focal Onset

A2M IGF2R IDE CR1

6.49e-0599644C0750900
DiseaseAlzheimer Disease, Early Onset

A2M IGF2R IDE CR1

6.49e-0599644C0750901
DiseasePresenile dementia

A2M IGF2R IDE CR1

6.49e-0599644C0011265
DiseaseAlzheimer Disease, Late Onset

A2M IGF2R IDE CR1

6.49e-0599644C0494463
DiseaseFamilial Alzheimer Disease (FAD)

A2M IGF2R IDE CR1

6.75e-05100644C0276496
Diseaseglycerophosphocholine measurement

SIDT1 LSAMP

6.91e-056642EFO_0010489
DiseaseAlzheimer's Disease

A2M IGF2R IDE CR1

7.02e-05101644C0002395
DiseaseLiver Cirrhosis

A2M LOX LOXL1 FGFR2

7.57e-05103644C0023890
DiseaseFibrosis, Liver

A2M LOX LOXL1 FGFR2

8.16e-05105644C0239946
Diseasebipolar II disorder

NCAN SLIT1

1.29e-048642EFO_0009964
Diseasedisease recurrence, malaria

PTPRM PTPRT

1.29e-048642EFO_0001068, EFO_0004952
Diseasesurvival time

LSAMP MCM10

1.65e-049642EFO_0000714
DiseaseC3 glomerulopathy

CFHR1 CFHR2

1.65e-049642C4087273
Diseaseaortic measurement

COL6A3 ADAMTS7 LOXL1 ACTN4 DCAF4

2.17e-04251645EFO_0020865
DiseaseMalignant neoplasm of lung

A2M SIDT2 ROBO1 FGFR2 PTPRT

2.83e-04266645C0242379
Diseasealcoholic liver disease

CNTNAP5 ROBO1 LSAMP

7.63e-0482643EFO_0008573
Diseaseresponse to anticonvulsant

COL6A3 CLSTN2 SP140

8.47e-0485643GO_0036277
Diseasecolorectal health

ADAMTS17 SEMA5A LSAMP DDX11

9.65e-04201644EFO_0008460
DiseaseHepatolenticular Degeneration

A2M LOX

1.24e-0324642C0019202
DiseaseHepatic Form of Wilson Disease

A2M LOX

1.24e-0324642C1527352
DiseaseNephrotic Syndrome

A2M NCK2

1.57e-0327642C0027726
Diseasetriacylglycerol 56:7 measurement

NCAN PTPRT

1.81e-0329642EFO_0010434
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement

SEMA5A DDX11

1.81e-0329642EFO_0004735, EFO_0004736
DiseaseAge related macular degeneration

CFHR1 CFHR2

1.94e-0330642C0242383

Protein segments in the cluster

PeptideGeneStartEntry
IFNNCHELYSREYQT

UNC13A

1011

Q9UPW8
YATNSAEVCQYVITH

ACSBG2

136

Q5FVE4
TTKCVRQYEGHVNEY

DCAF4

401

Q8WV16
VCLESEGRYYNAHIQ

ALG13

501

Q9NP73
TRAVTHNEQLCYQLY

ARHGEF3

361

Q9NR81
IVCNTVQNEDGFSHY

CLSTN3

396

Q9BQT9
VNYNNNHECIYSIQT

CSMD2

1116

Q7Z408
SAVEVCVVYGNYSQQ

CD28

61

P10747
NELDYYDSHNVNTRC

ACTN4

481

O43707
QHQYEILVTAYDCGQ

CLSTN2

226

Q9H4D0
FQHREVTCVYQLQNG

ADAMTS17

881

Q8TE56
VLYDVSHQCRLQYGA

ADAMTS7

466

Q9UKP4
DCINRHNVYINGITY

A2M

641

P01023
YSQVHICLRSGNYQE

INTS8

326

Q75QN2
AHDSTRVIQCYIQYG

PUM3

176

Q15397
YHTEDTRDQNQQCSY

KCNMB1

91

Q16558
CVVENEYGSINHTYH

FGFR2

231

P21802
YYGNVTRHQAECALN

NCK2

286

O43639
YICYARFNHTQTIQQ

NRCAM

216

Q92823
YVQEDSCQHGVYGRL

MTMR12

61

Q9C0I1
LYLACQEGHLEVTQY

ESPN

176

B1AK53
NVVRCNIHYTGRYVS

LOXL1

551

Q08397
DIQIVQVACGYYHSL

HERC4

136

Q5GLZ8
GSSVEYQCQNLYQLE

CFHR2

171

P36980
YHYLNQSGCVEDKTI

MYO10

286

Q9HD67
YQCRYEELRVTAGNH

KRT82

311

Q9NSB4
TQTVNLRDCEYCQYH

MCM10

401

Q7L590
YQNQSTCAVYHRSLI

MUC5AC

5526

P98088
CQAHSQLLQYVERYG

DDX11

416

Q96FC9
TQHFREQSECMIYQY

MMEL1

641

Q495T6
GYAVTRCHSYNLTVQ

PTPRT

411

O14522
NAYQELLQHYERCDV

G2E3

221

Q7L622
DHRGNITEYQCHQYI

GLG1

206

Q92896
RQQYECLHYKTDAQG

IL3RA

146

P26951
VYCVTQRSHLTQEYQ

KDM2B

371

Q8NHM5
NRENFHYGSVVTYRC

CR1

181

P17927
NRENFHYGSVVTYRC

CR1

631

P17927
NRENFHYGSVVTYRC

CR1

1081

P17927
DGVQQTTYLAQQYCH

PDSS1

371

Q5T2R2
GQTYHVAVVCYLRSQ

COL6A3

3051

P12111
LSDRTYTCQVTYQGH

IGHE

186

P01854
YTNNVVRCDIRYTGH

LOX

391

P28300
QTTTGECHFENYQRV

ITGA4

846

P13612
VYYEPSCTQNVNHGV

CTSS

266

P25774
QRNEVHNNCGIEIYY

IDE

781

P14735
SSVEYQCQNLYQLEG

CFHR1

231

Q03591
IHNVTAQENGIYRCY

BTN2A2

116

Q8WVV5
IYEQSCEVYRHQGNT

CNTNAP5

586

Q8WYK1
HYFICDVGNREEVYQ

DHRS3

91

O75911
VCGILYAVDTYNQQE

OLFML2A

581

Q68BL7
TVHYCYQVGGQEQVR

PTPRM

416

P28827
SLVHNGVSYYINLCQ

IGF2R

2016

P11717
REQCYEEDGGQYRIH

RTP2

126

Q5QGT7
YQTVVNVTGNQDICY

SIDT2

471

Q8NBJ9
TVTNVTEEHYGNYTC

LSAMP

276

Q13449
VHATVRYQCNEGFAQ

NCAN

1236

O14594
IYGVNQSQVQRYISC

SLC5A8

256

Q8N695
CYHQELSYQQGQVEQ

NINL

381

Q9Y2I6
GLRYLHTQYCHQQTE

REELD1

461

A0A1B0GV85
TYCQRYQQQSHDATV

SEMA5A

991

Q13591
ATDCYIVHEIYNGEN

TMEM11

26

P17152
YQTVVNVTGNQDICY

SIDT1

466

Q9NXL6
LVNAQCTDDYYRGHS

TRPV2

151

Q9Y5S1
TNVQRSDVGYYICQT

ROBO1

416

Q9Y6N7
LNEIYRSFQNVCYEH

SP140

126

Q13342
YEALRNCHRNSQVYG

ZSCAN29

266

Q8IWY8
DFHQVQRGYAICQTT

SLIT1

1466

O75093