Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	N6-methyladenosine-containing RNA reader activity	YTHDF1 YTHDF2 YTHDF3	7.25e-05	15	111	3	GO:1990247
GeneOntologyCellularComponent	MLL3/4 complex	NCOA6 KMT2D KDM6A	3.27e-05	12	113	3	GO:0044666
GeneOntologyCellularComponent	P-body	AGO2 TNRC6C YTHDF1 YTHDF2 YTHDF3	2.32e-04	102	113	5	GO:0000932
HumanPheno	Abnormal aortic valve morphology	AGO2 OGT POLR1A CLIP2 CHD7 JMJD1C KMT2D KANSL1 FANCI KDM6A	6.25e-06	289	32	10	HP:0001646
HumanPheno	Bicuspid aortic valve	AGO2 OGT POLR1A CLIP2 KMT2D KANSL1 KDM6A	6.60e-06	119	32	7	HP:0001647
HumanPheno	Abnormal aortic valve cusp morphology	AGO2 OGT POLR1A CLIP2 KMT2D KANSL1 KDM6A	7.37e-06	121	32	7	HP:0031567
HumanPheno	Overfolded helix	AGO2 CHD7 JMJD1C KMT2D KANSL1 KDM6A	9.39e-06	82	32	6	HP:0000396
HumanPheno	Abnormally folded helix	AGO2 CHD7 JMJD1C KMT2D KANSL1 KDM6A	1.61e-05	90	32	6	HP:0008544
HumanPheno	Renal hypoplasia	CLIP2 CHD7 JMJD1C ERCC8 KMT2D FANCI KDM6A	2.65e-05	147	32	7	HP:0000089
HumanPheno	Absent nipple	EDA KMT2D KDM6A	3.59e-05	11	32	3	HP:0002561
HumanPheno	Abdominal organ duplication	CLIP2 LAMA3 KMT2D KANSL1 KDM6A	5.97e-05	69	32	5	HP:0005217
HumanPheno	Renal duplication	CLIP2 LAMA3 KMT2D KANSL1 KDM6A	5.97e-05	69	32	5	HP:0000075
HumanPheno	Abnormality of the ureter	CLIP2 LAMA3 CHD7 JMJD1C SLC22A12 ERCC8 KMT2D KANSL1 FANCI KDM6A	7.37e-05	383	32	10	HP:0000069
HumanPheno	Choanal atresia	POLR1A CHD7 JMJD1C KMT2D FANCI KDM6A	9.50e-05	123	32	6	HP:0000453
HumanPheno	Reduced circulating growth hormone concentration	KMT2D FANCI KDM6A	9.74e-05	15	32	3	HP:0034323
HumanPheno	Abnormal ureter physiology	CLIP2 LAMA3 CHD7 JMJD1C KMT2D KANSL1 FANCI KDM6A	9.82e-05	245	32	8	HP:0025634
HumanPheno	Widely spaced teeth	ADNP EDA ERCC8 KMT2D KANSL1 KDM6A	1.04e-04	125	32	6	HP:0000687
HumanPheno	Abnormality of teeth spacing	ADNP EDA ERCC8 KMT2D KANSL1 KDM6A	1.14e-04	127	32	6	HP:0006478
HumanPheno	Abnormal alveolar type II pneumocyte morphology	KMT2D KDM6A	1.14e-04	3	32	2	HP:0033245
HumanPheno	Decreased proportion of CD4-positive, alpha-beta memory T cells	KMT2D KDM6A	1.14e-04	3	32	2	HP:0410386
HumanPheno	Type II pneumocyte hyperplasia	KMT2D KDM6A	1.14e-04	3	32	2	HP:0033328
HumanPheno	Choanal atresia or stenosis	POLR1A CHD7 JMJD1C KMT2D FANCI KDM6A	1.53e-04	134	32	6	HP:0000416
HumanPheno	Abnormal choanae morphology	POLR1A CHD7 JMJD1C KMT2D FANCI KDM6A	1.53e-04	134	32	6	HP:0000415
HumanPheno	Right ventricular hypertrophy	POLR1A KMT2D DEPDC5 KDM6A	1.60e-04	45	32	4	HP:0001667
HumanPheno	Aplasia of the semicircular canal	CHD7 KMT2D KDM6A	1.72e-04	18	32	3	HP:0011381
HumanPheno	Dimple chin	CHD7 KMT2D KDM6A	1.72e-04	18	32	3	HP:0010751
HumanPheno	Prominent fingertip pads	ADNP KMT2D KANSL1 KDM6A	1.74e-04	46	32	4	HP:0001212
HumanPheno	Lagophthalmos	KMT2D ECEL1 KDM6A	2.04e-04	19	32	3	HP:0030001
HumanPheno	Prominent digit pad	ADNP KMT2D KANSL1 KDM6A	2.06e-04	48	32	4	HP:0011298
HumanPheno	Scimitar anomaly	KMT2D KDM6A	2.28e-04	4	32	2	HP:0011626
HumanPheno	Hypoparathyroidism	CHD7 JMJD1C KMT2D KDM6A	2.41e-04	50	32	4	HP:0000829
HumanPheno	Interrupted aortic arch	CHD7 KMT2D KDM6A	3.20e-04	22	32	3	HP:0011611
HumanPheno	Abnormal growth hormone level	CHD7 ADNP KMT2D KANSL1 FANCI KDM6A	3.27e-04	154	32	6	HP:0032367
HumanPheno	Vesicoureteral reflux	CLIP2 CHD7 JMJD1C KMT2D KANSL1 FANCI KDM6A	3.50e-04	221	32	7	HP:0000076
HumanPheno	Dental malocclusion	AGO2 CLIP2 EDA ERCC8 KMT2D KDM6A	3.51e-04	156	32	6	HP:0000689
HumanPheno	Absent pubertal growth spurt	KMT2D KDM6A	3.78e-04	5	32	2	HP:0031087
HumanPheno	Renal tubular epithelial necrosis	LAMA3 SLC22A12	3.78e-04	5	32	2	HP:0008682
HumanPheno	Renal necrosis	LAMA3 SLC22A12	3.78e-04	5	32	2	HP:0032618
HumanPheno	Branchial sinus	KMT2D KDM6A	3.78e-04	5	32	2	HP:0100272
HumanPheno	Patent ductus arteriosus	AGO2 POLR1A CLIP2 CHD7 JMJD1C KMT2D KANSL1 FANCI KDM6A	4.05e-04	382	32	9	HP:0001643
HumanPheno	Duplicated collecting system	LAMA3 KMT2D KDM6A	4.17e-04	24	32	3	HP:0000081
HumanPheno	Abnormal thymus morphology	CHD7 JMJD1C ERCC8 KMT2D	4.29e-04	58	32	4	HP:0000777
HumanPheno	Vertebral segmentation defect	CLIP2 CHD7 KMT2D KANSL1 FANCI KDM6A	4.30e-04	162	32	6	HP:0003422
HumanPheno	Abnormal renal morphology	CLCA4 ADAMTSL1 POLR1A CLIP2 MYO5B LAMA3 CHD7 ADNP JMJD1C SLC22A12 ERCC8 KMT2D KANSL1 FANCI ANKRD17 DEPDC5 KDM6A	4.65e-04	1252	32	17	HP:0012210
HumanPheno	Abnormal finger morphology	TET2 ADAMTSL1 AGO2 OGT POLR1A CLIP2 LAMA3 CHD7 ADNP EDA JMJD1C ERCC8 KMT2D KANSL1 FANCI ECEL1 KDM6A TOR1AIP1	4.77e-04	1385	32	18	HP:0001167
HumanPheno	Chiari malformation	CLIP2 KMT2D KANSL1 FANCI KDM6A	4.77e-04	107	32	5	HP:0002308
HumanPheno	Abnormal aortic arch morphology	CLIP2 CHD7 JMJD1C KMT2D KDM6A	5.20e-04	109	32	5	HP:0012303
HumanPheno	Abnormal semicircular canal morphology	CHD7 KMT2D KDM6A	5.31e-04	26	32	3	HP:0011380
HumanPheno	Abnormal ureter morphology	LAMA3 SLC22A12 ERCC8 KMT2D FANCI KDM6A	5.39e-04	169	32	6	HP:0025633
HumanPheno	Abnormal dermatoglyphics	ADAMTSL1 POLR1A CLIP2 CHD7 ADNP KMT2D DEPDC5 KDM6A	5.44e-04	314	32	8	HP:0007477
HumanPheno	Eversion of lateral third of lower eyelids	KMT2D KDM6A	5.65e-04	6	32	2	HP:0007655
HumanPheno	Bilateral renal hypoplasia	KMT2D KDM6A	5.65e-04	6	32	2	HP:0012584
HumanPheno	Abnormality of dental eruption	ADAMTSL1 CHD7 ADNP EDA ERCC8 KMT2D KDM6A	5.77e-04	240	32	7	HP:0006292
HumanPheno	Abnormal aortic morphology	POLR1A CLIP2 CHD7 JMJD1C ERCC8 KMT2D KANSL1 FANCI KDM6A	5.80e-04	401	32	9	HP:0001679
HumanPheno	Abnormal heart valve morphology	AGO2 OGT POLR1A CLIP2 CHD7 ADNP JMJD1C KMT2D KANSL1 FANCI KDM6A	5.83e-04	588	32	11	HP:0001654
HumanPheno	Decreased proportion of memory B cells	TET2 KMT2D KDM6A	5.95e-04	27	32	3	HP:0030374
HumanPheno	Abnormal proportion of memory B cells	TET2 KMT2D KDM6A	5.95e-04	27	32	3	HP:0030373
HumanPheno	Functional abnormality of the bladder	CLIP2 LAMA3 CHD7 ADNP JMJD1C ERCC8 KMT2D KANSL1 FANCI DEPDC5 KDM6A	6.00e-04	590	32	11	HP:0000009
HumanPheno	Carious teeth	CLIP2 LAMA3 ADNP JMJD1C ERCC8 KMT2D	6.30e-04	174	32	6	HP:0000670
HumanPheno	Oligodontia	ADNP EDA KMT2D KDM6A	6.64e-04	65	32	4	HP:0000677
HumanPheno	Abnormality of the chin	ADAMTSL1 CLIP2 CHD7 ADNP EDA ERCC8 KMT2D KANSL1 KDM6A	6.71e-04	409	32	9	HP:0000306
HumanPheno	Abnormality of external features of the abdomen	CLIP2 CHD7 ADNP JMJD1C KMT2D FANCI DEPDC5 KDM6A	6.99e-04	326	32	8	HP:0001462
HumanPheno	Decreased proportion of memory T cells	KMT2D KDM6A	7.87e-04	7	32	2	HP:0032183
HumanPheno	Anterior hypopituitarism	CHD7 ADNP EDA KMT2D KANSL1 KDM6A	7.99e-04	182	32	6	HP:0000830
HumanPheno	Clinodactyly of the 5th finger	AGO2 OGT POLR1A CLIP2 CHD7 ADNP KMT2D FANCI KDM6A	8.14e-04	420	32	9	HP:0004209
HumanPheno	Abnormal renal collecting system morphology	LAMA3 KMT2D KDM6A	8.15e-04	30	32	3	HP:0004742
HumanPheno	Abnormality of the helix	AGO2 CHD7 JMJD1C KMT2D KANSL1 KDM6A	8.23e-04	183	32	6	HP:0000380
HumanPheno	Clinodactyly of hands	AGO2 OGT POLR1A CLIP2 CHD7 ADNP KMT2D FANCI KDM6A	8.28e-04	421	32	9	HP:0001157
HumanPheno	Deviation of the 5th finger	AGO2 OGT POLR1A CLIP2 CHD7 ADNP KMT2D FANCI KDM6A	8.28e-04	421	32	9	HP:0009179
HumanPheno	Cupped ear	CHD7 ADNP KMT2D KDM6A	8.33e-04	69	32	4	HP:0000378
HumanPheno	Tetralogy of Fallot	CLIP2 CHD7 JMJD1C KMT2D FANCI KDM6A	8.71e-04	185	32	6	HP:0001636
HumanPheno	Abnormal B cell subset distribution	TET2 KMT2D KDM6A	8.98e-04	31	32	3	HP:0025539
HumanPheno	Long palpebral fissure	POLR1A ADNP KMT2D KDM6A	9.28e-04	71	32	4	HP:0000637
HumanPheno	Abnormality of the bladder	CLIP2 LAMA3 CHD7 ADNP JMJD1C ERCC8 KMT2D KANSL1 FANCI DEPDC5 KDM6A	9.31e-04	621	32	11	HP:0000014
HumanPheno	Congenital hypothyroidism	ADAMTSL1 KMT2D KDM6A	9.87e-04	32	32	3	HP:0000851
HumanPheno	Abnormal esophagus morphology	CLCA4 AGO2 POLR1A CLIP2 LAMA3 CHD7 ADNP EDA JMJD1C ERCC8 KMT2D KANSL1 FANCI QDPR KDM6A	1.01e-03	1078	32	15	HP:0002031
HumanPheno	Hydronephrosis	POLR1A LAMA3 CHD7 ERCC8 KMT2D KANSL1 KDM6A	1.02e-03	264	32	7	HP:0000126
HumanPheno	Hypopituitarism	CHD7 ADNP EDA KMT2D KANSL1 KDM6A	1.03e-03	191	32	6	HP:0040075
HumanPheno	Abnormal palmar dermatoglyphics	ADAMTSL1 POLR1A CHD7 ADNP KMT2D DEPDC5 KDM6A	1.04e-03	265	32	7	HP:0001018
HumanPheno	Abnormal pulmonary alveolar system morphology	KMT2D KDM6A	1.05e-03	8	32	2	HP:0033137
HumanPheno	Anoperineal fistula	KMT2D KDM6A	1.05e-03	8	32	2	HP:0005218
HumanPheno	Abnormal morphology of the vestibule of the inner ear	CHD7 KMT2D KDM6A	1.08e-03	33	32	3	HP:0011376
HumanPheno	Abnormal stomach morphology	TET2 CLCA4 AGO2 CLIP2 LAMA3 CHD7 ADNP JMJD1C ERCC8 KMT2D KANSL1 KDM6A	1.14e-03	742	32	12	HP:0002577
HumanPheno	Microtia	AGO2 POLR1A CHD7 ADNP KMT2D KDM6A	1.15e-03	195	32	6	HP:0008551
HumanPheno	Anal stenosis	CHD7 KMT2D KDM6A	1.18e-03	34	32	3	HP:0002025
HumanPheno	Calcaneovalgus deformity	ADAMTSL1 KANSL1 ECEL1	1.18e-03	34	32	3	HP:0001848
HumanPheno	Macrotia	ADAMTSL1 POLR1A CLIP2 ERCC8 KMT2D KANSL1 KDM6A	1.19e-03	271	32	7	HP:0000400
HumanPheno	Regional abnormality of skin	ADAMTSL1 POLR1A CLIP2 LAMA3 CHD7 ADNP KMT2D KANSL1 DEPDC5 KDM6A	1.24e-03	541	32	10	HP:0011356
HumanPheno	Atrial septal defect	AGO2 POLR1A CLIP2 CHD7 ADNP JMJD1C KMT2D KANSL1 FANCI KDM6A	1.24e-03	541	32	10	HP:0001631
HumanPheno	Abnormality of the atrial septum	AGO2 POLR1A CLIP2 CHD7 ADNP JMJD1C KMT2D KANSL1 FANCI KDM6A	1.24e-03	541	32	10	HP:0001630
HumanPheno	Abnormal pulmonary valve morphology	AGO2 CLIP2 CHD7 JMJD1C KANSL1 KDM6A	1.24e-03	198	32	6	HP:0001641
HumanPheno	Deformed tarsal bones	ADAMTSL1 KANSL1 ECEL1	1.29e-03	35	32	3	HP:0008119
HumanPheno	Abnormal atrial septum morphology	AGO2 POLR1A CLIP2 CHD7 ADNP JMJD1C KMT2D KANSL1 FANCI KDM6A	1.30e-03	544	32	10	HP:0011994
HumanPheno	Radial deviation of finger	AGO2 OGT POLR1A CLIP2 CHD7 ADNP KMT2D FANCI KDM6A	1.30e-03	448	32	9	HP:0009466
HumanPheno	Renal hypoplasia/aplasia	CLIP2 CHD7 JMJD1C ERCC8 KMT2D FANCI ANKRD17 KDM6A	1.32e-03	359	32	8	HP:0008678
HumanPheno	Anal fistula	KMT2D KDM6A	1.34e-03	9	32	2	HP:0010447
HumanPheno	Pineal cyst	ADNP KANSL1	1.34e-03	9	32	2	HP:0012683
HumanPheno	Alobar holoprosencephaly	KMT2D KDM6A	1.34e-03	9	32	2	HP:0006988
HumanPheno	Pilomatrixoma	KMT2D KDM6A	1.34e-03	9	32	2	HP:0030434
HumanPheno	Bilateral choanal atresia	POLR1A KMT2D	1.34e-03	9	32	2	HP:0004502
HumanPheno	Abnormal proportion of memory T cells	KMT2D KDM6A	1.34e-03	9	32	2	HP:0032182
HumanPheno	Patent foramen ovale	AGO2 POLR1A KMT2D FANCI KDM6A	1.37e-03	135	32	5	HP:0001655
HumanPheno	Finger clinodactyly	AGO2 OGT POLR1A CLIP2 CHD7 ADNP KMT2D FANCI KDM6A	1.38e-03	452	32	9	HP:0040019
Domain	Ank	TRPA1 ANK2 ANK3 ANKLE1 ANKRD27 ASB13 ANKRD17 POTEI POTEA AGAP7P	1.06e-06	228	111	10	PF00023
Domain	YTH	YTHDF1 YTHDF2 YTHDF3	2.03e-06	5	111	3	PF04146
Domain	YTH_domain	YTHDF1 YTHDF2 YTHDF3	2.03e-06	5	111	3	IPR007275
Domain	YTH	YTHDF1 YTHDF2 YTHDF3	2.03e-06	5	111	3	PS50882
Domain	ANK	TRPA1 ANK2 ANK3 ANKLE1 ANKRD27 ASB13 ANKRD17 POTEI POTEA AGAP7P	2.52e-06	251	111	10	SM00248
Domain	ANK_REPEAT	TRPA1 ANK2 ANK3 ANKLE1 ANKRD27 ASB13 ANKRD17 POTEI POTEA AGAP7P	2.71e-06	253	111	10	PS50088
Domain	Ankyrin_rpt-contain_dom	TRPA1 ANK2 ANK3 ANKLE1 ANKRD27 ASB13 ANKRD17 POTEI POTEA AGAP7P	2.80e-06	254	111	10	IPR020683
Domain	ANK_REP_REGION	TRPA1 ANK2 ANK3 ANKLE1 ANKRD27 ASB13 ANKRD17 POTEI POTEA AGAP7P	2.80e-06	254	111	10	PS50297
Domain	Ankyrin_rpt	TRPA1 ANK2 ANK3 ANKLE1 ANKRD27 ASB13 ANKRD17 POTEI POTEA AGAP7P	3.70e-06	262	111	10	IPR002110
Domain	Ank_2	TRPA1 ANK2 ANK3 ANKLE1 ANKRD27 ASB13 ANKRD17 POTEI POTEA	5.50e-06	215	111	9	PF12796
Domain	-	TRPA1 ANK2 ANK3 ANKLE1 ANKRD27 ASB13 ANKRD17 POTEI POTEA	1.73e-05	248	111	9	1.25.40.20
Domain	-	GART SEPHS2	1.05e-04	3	111	2	3.90.650.10
Domain	ZF_ZZ_2	ZSWIM2 ZZEF1 UTRN	1.56e-04	18	111	3	PS50135
Domain	ZF_ZZ_1	ZSWIM2 ZZEF1 UTRN	1.56e-04	18	111	3	PS01357
Domain	ZZ	ZSWIM2 ZZEF1 UTRN	1.56e-04	18	111	3	PF00569
Domain	Znf_ZZ	ZSWIM2 ZZEF1 UTRN	1.85e-04	19	111	3	IPR000433
Domain	ZnF_ZZ	ZSWIM2 ZZEF1 UTRN	1.85e-04	19	111	3	SM00291
Domain	-	GART SEPHS2	2.08e-04	4	111	2	3.30.1330.10
Domain	AIRS_C	GART SEPHS2	2.08e-04	4	111	2	PF02769
Domain	AIRS	GART SEPHS2	2.08e-04	4	111	2	PF00586
Domain	PurM-like_N	GART SEPHS2	2.08e-04	4	111	2	IPR016188
Domain	AIR_synth_C_dom	GART SEPHS2	2.08e-04	4	111	2	IPR010918
Domain	zf-C2H2	SP3 ZNF613 ADNP ZNF25 ZXDA ZNF587B ZNF34 ZBTB49 ZNF776 GLI4 ZNF587 ZNF81 ZNF417	2.40e-04	693	111	13	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	SP3 ZNF613 ADNP ZNF25 ZXDA ZNF587B ZNF34 ZBTB49 ZNF776 GLI4 ZNF587 ZNF81 ZNF417	2.43e-04	694	111	13	IPR013087
Domain	ZINC_FINGER_C2H2_2	SP3 ZNF613 ADNP ZNF25 ZXDA ZNF587B ZNF34 ZBTB49 ZNF776 GLI4 ZNF587 ZNF81 ZNF417	6.91e-04	775	111	13	PS50157
Domain	ZINC_FINGER_C2H2_1	SP3 ZNF613 ADNP ZNF25 ZXDA ZNF587B ZNF34 ZBTB49 ZNF776 GLI4 ZNF587 ZNF81 ZNF417	7.08e-04	777	111	13	PS00028
Domain	-	SP3 ZNF613 ZNF25 ZXDA ZNF587B ZNF34 ZBTB49 ZNF776 GLI4 ZNF587 ZNF81 ZNF417	7.13e-04	679	111	12	3.30.160.60
Domain	Znf_C2H2-like	SP3 ZNF613 ADNP ZNF25 ZXDA ZNF587B ZNF34 ZBTB49 ZNF776 GLI4 ZNF587 ZNF81 ZNF417	8.85e-04	796	111	13	IPR015880
Domain	Znf_C2H2	SP3 ZNF613 ADNP ZNF25 ZXDA ZNF587B ZNF34 ZBTB49 ZNF776 GLI4 ZNF587 ZNF81 ZNF417	9.80e-04	805	111	13	IPR007087
Domain	ZnF_C2H2	SP3 ZNF613 ADNP ZNF25 ZXDA ZNF587B ZNF34 ZBTB49 ZNF776 GLI4 ZNF587 ZNF81 ZNF417	1.01e-03	808	111	13	SM00355
Domain	ZU5	ANK2 ANK3	1.23e-03	9	111	2	SM00218
Domain	KRAB	ZNF613 ZNF25 ZNF587B ZNF34 ZNF776 ZNF587 ZNF81 ZNF417	1.34e-03	358	111	8	PS50805
Domain	KRAB	ZNF613 ZNF25 ZNF587B ZNF34 ZNF776 ZNF587 ZNF81 ZNF417	1.34e-03	358	111	8	PF01352
Domain	MAC_perforin	ASTN1 C6	1.53e-03	10	111	2	IPR001862
Domain	ZU5	ANK2 ANK3	1.53e-03	10	111	2	PS51145
Domain	Ank_3	ANK3 ANKRD27	1.53e-03	10	111	2	PF13606
Domain	KRAB	ZNF613 ZNF25 ZNF587B ZNF34 ZNF776 ZNF587 ZNF81 ZNF417	1.62e-03	369	111	8	SM00349
Domain	KRAB	ZNF613 ZNF25 ZNF587B ZNF34 ZNF776 ZNF587 ZNF81 ZNF417	1.65e-03	370	111	8	IPR001909
Domain	MACPF	ASTN1 C6	2.22e-03	12	111	2	IPR020864
Domain	MACPF	ASTN1 C6	2.22e-03	12	111	2	SM00457
Domain	ZU5	ANK2 ANK3	2.22e-03	12	111	2	PF00791
Domain	ZU5_dom	ANK2 ANK3	2.22e-03	12	111	2	IPR000906
Domain	EGF-like_dom	STAB2 LAMA3 CD93 ASTN1 PLAT C6	3.73e-03	249	111	6	IPR000742
Domain	TPR_8	OGT TMTC2 KDM6A	3.86e-03	53	111	3	PF13181
Domain	EGF-like_CS	STAB2 LAMA3 CD93 ASTN1 PLAT C6	4.69e-03	261	111	6	IPR013032
Domain	EGF_2	STAB2 LAMA3 CD93 ASTN1 PLAT C6	5.05e-03	265	111	6	PS01186
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	NCOA6 OGT KMT2D KANSL1 KDM6A	4.49e-06	42	83	5	M48018
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	OGT KMT2D KANSL1 KDM6A	7.08e-05	38	83	4	MM17073
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	NCOA3 NCOA6 TBRG4 JMJD1C PREB YTHDF1 JUND KMT2D RAVER2 ANKRD17 TOR1AIP1 MAML3 YTHDF2 YTHDF3	3.15e-10	457	113	14	32344865
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TET2 NCOA6 TBRG4 AGO2 ADNP ZZEF1 FOXJ3 ANKRD27 TIAM2 SENP6 ANKRD17 DEPDC5 HHIPL1 AGAP7P	2.07e-09	529	113	14	14621295
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NCOA3 NCOA6 CHD7 ADNP JMJD1C KMT2D KDM6A	1.07e-08	83	113	7	28794006
Pubmed	YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.	YTHDF1 YTHDF2 YTHDF3	3.34e-08	3	113	3	28106072
Pubmed	YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation.	YTHDF1 YTHDF2 YTHDF3	3.34e-08	3	113	3	35508130
Pubmed	A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA.	YTHDF1 YTHDF2 YTHDF3	3.34e-08	3	113	3	32492408
Pubmed	m6A enhances the phase separation potential of mRNA.	YTHDF1 YTHDF2 YTHDF3	3.34e-08	3	113	3	31292544
Pubmed	Comprehensive Analysis of YTH Domain Family in Lung Adenocarcinoma: Expression Profile, Association with Prognostic Value, and Immune Infiltration.	YTHDF1 YTHDF2 YTHDF3	3.34e-08	3	113	3	34497675
Pubmed	m6A-binding YTHDF proteins promote stress granule formation.	YTHDF1 YTHDF2 YTHDF3	3.34e-08	3	113	3	32451507
Pubmed	N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression.	YTHDF1 YTHDF2 YTHDF3	3.34e-08	3	113	3	27371828
Pubmed	N6-methyladenosine-dependent regulation of messenger RNA stability.	YTHDF1 YTHDF2 YTHDF3	1.33e-07	4	113	3	24284625
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	JCAD NCOA3 NCOA6 ARHGAP32 TBRG4 ABCA4 CHD7 FOXJ3 MEPE KMT2D ANKRD17 KDM6A MAML3	1.69e-07	638	113	13	31182584
Pubmed	Human transcription factor protein interaction networks.	TET2 NCOA3 NCOA6 ARHGAP32 AGO2 OGT CHD7 TNRC6C ADNP JMJD1C YTHDF1 JUND KMT2D KANSL1 ANKRD17 KDM6A LRIF1 YTHDF2 YTHDF3	1.74e-07	1429	113	19	35140242
Pubmed	Context-dependent functional compensation between Ythdf m6A reader proteins.	YTHDF1 YTHDF2 YTHDF3	3.32e-07	5	113	3	32943573
Pubmed	PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands.	TET2 OGT KDM6A	3.32e-07	5	113	3	34667079
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	NCOA6 OGT KMT2D KDM6A	4.92e-07	20	113	4	29785026
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	ARHGAP32 AGO2 CLIP2 TNRC6C PRAG1 YTHDF1 AGAP7P QDPR	6.10e-07	218	113	8	33378226
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	NCOA6 OGT ADNP ANKRD27 FBXO30 KMT2D KANSL1 FBXO4 FANCI KDM6A LRIF1	6.85e-07	495	113	11	27705803
Pubmed	Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.	AGO2 GART YTHDF1 ANKRD17 YTHDF2 YTHDF3	1.42e-06	107	113	6	30995489
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NCOA3 NCOA6 CHD7 JUND KMT2D KANSL1 FBXO4 EIF4G2 SENP6 ANKRD17 UTP20 TLN2 KDM6A	1.48e-06	774	113	13	15302935
Pubmed	Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.	NCOA6 KMT2D KDM6A	1.85e-06	8	113	3	17178841
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF25 ZNF587B ZNF34 ZNF776 ZNF587 ZNF417 YTHDF2	2.23e-06	181	113	7	37372979
Pubmed	Interaction network of human early embryonic transcription factors.	TET2 NCOA3 NCOA6 OGT CHD7 KMT2D KDM6A LRIF1 YTHDF3	2.33e-06	351	113	9	38297188
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TET2 NCOA3 NCOA6 OGT CHD7 JMJD1C KMT2D KDM6A	2.85e-06	268	113	8	33640491
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NCOA6 FRYL ANKLE1 TNRC6C ZZEF1 PRAG1 TIAM2 JUND SEPHS2 KMT2D KANSL1 FANCI TLN2 DEPDC5 IQGAP3	3.05e-06	1105	113	15	35748872
Pubmed	Functional proteomics mapping of a human signaling pathway.	NCOA6 ANK3 ZZEF1 ANKRD27 ZNF587B KMT2D KANSL1 ZNF587 EIF4G2 UTRN KDM6A	3.78e-06	591	113	11	15231748
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	CHD7 FOXJ3 YTHDF1 PLAT UTRN YTHDF2 YTHDF3	3.91e-06	197	113	7	20811636
Pubmed	The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.	NCOA3 NCOA6 JMJD1C	5.41e-06	11	113	3	36613751
Pubmed	Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.	NCOA3 NCOA6 CHD7 JMJD1C KMT2D	5.79e-06	78	113	5	28611094
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	TBRG4 OGT CHD7 YTHDF1 KMT2D UTP20 UTRN YTHDF2 YTHDF3	8.17e-06	410	113	9	26949251
Pubmed	High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A.	SP3 OGT VCAM1	9.33e-06	13	113	3	17670746
Pubmed	Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.	NCOA6 KMT2D KDM6A	9.33e-06	13	113	3	17761849
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 NCOA3 OGT CHD7 ADNP JMJD1C KMT2D ANKRD17 UTRN	9.53e-06	418	113	9	34709266
Pubmed	Kabuki Syndrome	KMT2D KDM6A	1.05e-05	2	113	2	21882399
Pubmed	Hypermobility in individuals with Kabuki syndrome: The effect of growth hormone treatment.	KMT2D KDM6A	1.05e-05	2	113	2	30556359
Pubmed	Cytoplasmic m6A reader YTHDF3 promotes mRNA translation.	YTHDF1 YTHDF3	1.05e-05	2	113	2	28106076
Pubmed	Deletion of YTHDF1 (not YTHDF3) reduced brain and gut damage after traumatic brain injury.	YTHDF1 YTHDF3	1.05e-05	2	113	2	39081030
Pubmed	Anti-obesity and anti-hyperglycemic effects of cinnamaldehyde via altered ghrelin secretion and functional impact on food intake and gastric emptying.	GHRL TRPA1	1.05e-05	2	113	2	25605129
Pubmed	Identification of KMT2D and KDM6A mutations by exome sequencing in Korean patients with Kabuki syndrome.	KMT2D KDM6A	1.05e-05	2	113	2	24739679
Pubmed	MLL2 and KDM6A mutations in patients with Kabuki syndrome.	KMT2D KDM6A	1.05e-05	2	113	2	23913813
Pubmed	Identification of KMT2D and KDM6A variants by targeted sequencing from patients with Kabuki syndrome and other congenital disorders.	KMT2D KDM6A	1.05e-05	2	113	2	31935506
Pubmed	YTHDF1 and YTHDF2 are associated with better patient survival and an inflamed tumor-immune microenvironment in non-small-cell lung cancer.	YTHDF1 YTHDF2	1.05e-05	2	113	2	34408926
Pubmed	Update of the genotype and phenotype of KMT2D and KDM6A by genetic screening of 100 patients with clinically suspected Kabuki syndrome.	KMT2D KDM6A	1.05e-05	2	113	2	32803813
Pubmed	N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency.	YTHDF1 YTHDF2	1.05e-05	2	113	2	26046440
Pubmed	The mechanism underlying redundant functions of the YTHDF proteins.	YTHDF1 YTHDF2	1.05e-05	2	113	2	36694229
Pubmed	YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways.	YTHDF2 YTHDF3	1.05e-05	2	113	2	32905781
Pubmed	Prenatal and perinatal history in Kabuki Syndrome.	KMT2D KDM6A	1.05e-05	2	113	2	31654559
Pubmed	The phenotypic spectrum of Kabuki syndrome in patients of Chinese descent: A case series.	KMT2D KDM6A	1.05e-05	2	113	2	31883305
Pubmed	SETting up the genome: KMT2D and KDM6A genomic function in the Kabuki syndrome craniofacial developmental disorder.	KMT2D KDM6A	1.05e-05	2	113	2	37800171
Pubmed	Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.	KMT2D KDM6A	1.05e-05	2	113	2	23184418
Pubmed	Kabuki syndrome genes KMT2D and KDM6A: functional analyses demonstrate critical roles in craniofacial, heart and brain development.	KMT2D KDM6A	1.05e-05	2	113	2	25972376
Pubmed	Prenatal Phenotype of Kabuki Syndrome: Seven Case Series.	KMT2D KDM6A	1.05e-05	2	113	2	36436503
Pubmed	CHARGE and Kabuki Syndromes: Gene-Specific DNA Methylation Signatures Identify Epigenetic Mechanisms Linking These Clinically Overlapping Conditions.	CHD7 KMT2D	1.05e-05	2	113	2	28475860
Pubmed	Clinical and molecular characterization study of Chinese Kabuki syndrome in Hong Kong.	KMT2D KDM6A	1.05e-05	2	113	2	33314698
Pubmed	The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.	ANK2 ANK3	1.05e-05	2	113	2	11781319
Pubmed	Structural basis of diverse membrane target recognitions by ankyrins.	ANK2 ANK3	1.05e-05	2	113	2	25383926
Pubmed	Kabuki syndrome: clinical and molecular diagnosis in the first year of life.	KMT2D KDM6A	1.05e-05	2	113	2	25281733
Pubmed	Recurrent giant cell fibroblastoma: Malignancy predisposition in Kabuki syndrome revisited.	KMT2D KDM6A	1.05e-05	2	113	2	26898171
Pubmed	Hybrid selection of transcribed sequences from microdissected DNA: isolation of genes within amplified region at 20q11-q13.2 in breast cancer.	NCOA3 NCOA6	1.05e-05	2	113	2	8758910
Pubmed	Molecular genetic analysis in 14 Czech Kabuki syndrome patients is confirming the utility of phenotypic scoring.	KMT2D KDM6A	1.05e-05	2	113	2	26841933
Pubmed	Congenital hyperinsulinism as the presenting feature of Kabuki syndrome: clinical and molecular characterization of 9 affected individuals.	KMT2D KDM6A	1.05e-05	2	113	2	29907798
Pubmed	Kabuki syndrome: expanding the phenotype to include microphthalmia and anophthalmia.	KMT2D KDM6A	1.05e-05	2	113	2	26049589
Pubmed	Absence of deletion and duplication of MLL2 and KDM6A genes in a large cohort of patients with Kabuki syndrome.	KMT2D KDM6A	1.05e-05	2	113	2	22840376
Pubmed	Mutation Update for Kabuki Syndrome Genes KMT2D and KDM6A and Further Delineation of X-Linked Kabuki Syndrome Subtype 2.	KMT2D KDM6A	1.05e-05	2	113	2	27302555
Pubmed	Somatic mutations in KMT2D and TET2 associated with worse prognosis in Epstein-Barr virus-associated T or natural killer-cell lymphoproliferative disorders.	TET2 KMT2D	1.05e-05	2	113	2	31311407
Pubmed	YTHDF1 promotes mRNA degradation via YTHDF1-AGO2 interaction and phase separation.	AGO2 YTHDF1	1.05e-05	2	113	2	34821414
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	JCAD NCOA6 SP3 ARHGAP32 ANK3 CHD7 ADNP BLZF1 FOXJ3	1.19e-05	430	113	9	35044719
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TET2 NCOA3 NCOA6 OGT CHD7 ADNP FOXJ3 JMJD1C JUND KMT2D FANCI EIF4G2 KDM6A LRIF1	1.42e-05	1103	113	14	34189442
Pubmed	The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex.	NCOA6 KMT2D KDM6A	1.48e-05	15	113	3	17925232
Pubmed	H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.	NCOA6 KMT2D KDM6A	1.81e-05	16	113	3	24368734
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TET2 JCAD OGT ANK2 ANK3 CLIP2 DNAJB9 ZNF34 EIF4G2 LRRCC1 SENP6 ASTN1 TLN2 UTRN KDM6A	1.83e-05	1285	113	15	35914814
Pubmed	Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.	NCOA6 OGT KMT2D KDM6A	2.17e-05	50	113	4	37974198
Pubmed	MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.	NCOA6 KMT2D KDM6A	2.20e-05	17	113	3	26180087
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TET2 JCAD CCP110 NCOA6 ARHGAP32 FRYL PRAG1 ANKRD27 ANKRD17 NUB1 UTRN YTHDF2	2.46e-05	861	113	12	36931259
Pubmed	PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.	NCOA6 KMT2D KDM6A	2.63e-05	18	113	3	17500065
Pubmed	m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs.	YTHDF1 YTHDF2 YTHDF3	3.12e-05	19	113	3	36039295
Pubmed	Mutually exclusive mutation profiles define functionally related genes in muscle invasive bladder cancer.	KMT2D KDM6A	3.13e-05	3	113	2	35073341
Pubmed	Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation.	KMT2D KDM6A	3.13e-05	3	113	2	34463256
Pubmed	YTH: a new domain in nuclear proteins.	YTHDF2 YTHDF3	3.13e-05	3	113	2	12368078
Pubmed	Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance).	CHD7 KMT2D	3.13e-05	3	113	2	28007623
Pubmed	The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression.	KMT2D KDM6A	3.13e-05	3	113	2	37410700
Pubmed	The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.	ANK2 ANK3	3.13e-05	3	113	2	15611082
Pubmed	Human ankyrins and their contribution to disease biology: An update.	ANK2 ANK3	3.13e-05	3	113	2	33410423
Pubmed	Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq.	YTHDF2 YTHDF3	3.13e-05	3	113	2	22575960
Pubmed	m6A modification controls the innate immune response to infection by targeting type I interferons.	YTHDF2 YTHDF3	3.13e-05	3	113	2	30559377
Pubmed	The t-PA -7351C>T enhancer polymorphism decreases Sp1 and Sp3 protein binding affinity and transcriptional responsiveness to retinoic acid.	SP3 PLAT	3.13e-05	3	113	2	15466927
Pubmed	The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome.	TET2 KMT2D	3.13e-05	3	113	2	26551667
Pubmed	Spatial regulation and activity modulation of plasmin by high affinity binding to the G domain of the alpha 3 subunit of laminin-5.	LAMA3 PLAT	3.13e-05	3	113	2	10956663
Pubmed	The m6 A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons.	YTHDF1 YTHDF2	3.13e-05	3	113	2	34643063
Pubmed	Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.	ANK2 ANK3	3.13e-05	3	113	2	34289389
Pubmed	A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription.	KMT2D KDM6A	3.13e-05	3	113	2	28732206
Pubmed	TET2 promotes histone O-GlcNAcylation during gene transcription.	TET2 OGT	3.13e-05	3	113	2	23222540
Pubmed	FBXW7 Triggers Degradation of KMT2D to Favor Growth of Diffuse Large B-cell Lymphoma Cells.	NCOA6 KMT2D KDM6A	3.66e-05	20	113	3	32350066
Pubmed	Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.	NCOA6 KMT2D KDM6A	3.66e-05	20	113	3	19047629
Pubmed	Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.	NCOA3 NCOA6 JMJD1C	4.26e-05	21	113	3	19596656
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	NCOA6 OGT JUND KMT2D KDM6A	4.50e-05	119	113	5	23508102
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	NCOA6 KMT2D KDM6A	4.92e-05	22	113	3	26886794
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	TET2 JCAD NCOA3 CHD7 JMJD1C ZNF587B KMT2D KDM6A	4.93e-05	398	113	8	35016035
Pubmed	cDNAs with long CAG trinucleotide repeats from human brain.	NCOA3 KMT2D MAML3	5.64e-05	23	113	3	9225980
Pubmed	PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.	NCOA6 OGT KMT2D KDM6A	6.14e-05	65	113	4	22496869
Interaction	NUP35 interactions	NCOA3 NCOA6 JMJD1C PREB YTHDF1 JUND KMT2D RAVER2 ANKRD17 MAML3 YTHDF2 YTHDF3	3.88e-06	424	111	12	int:NUP35
Interaction	SOX7 interactions	TET2 NCOA3 CHD7 JMJD1C KMT2D KDM6A	6.07e-06	82	111	6	int:SOX7
Interaction	CXXC1 interactions	TET2 NCOA6 OGT EDA KMT2D KANSL1 KDM6A	8.50e-06	132	111	7	int:CXXC1
Interaction	SMG7 interactions	NCOA3 NCOA6 AGO2 TNRC6C JMJD1C YTHDF1 KMT2D ANKRD17 YTHDF2 YTHDF3	1.08e-05	319	111	10	int:SMG7
Interaction	CPEB4 interactions	ARHGAP32 AGO2 TNRC6C YTHDF1 ANKRD17 YTHDF2 YTHDF3	2.52e-05	156	111	7	int:CPEB4
Interaction	CNOT11 interactions	OGT TNRC6C YTHDF1 ANKRD17 YTHDF2 YTHDF3	3.63e-05	112	111	6	int:CNOT11
Interaction	GCM1 interactions	TET2 NCOA3 YTHDF1 KMT2D KDM6A	3.66e-05	68	111	5	int:GCM1
Interaction	CEP85 interactions	ARHGAP32 AGO2 TNRC6C YTHDF1 ANKRD17 YTHDF2 YTHDF3	4.21e-05	169	111	7	int:CEP85
Interaction	CNOT9 interactions	CCP110 AGO2 TNRC6C JMJD1C YTHDF1 ANKRD17 YTHDF2 YTHDF3	4.23e-05	231	111	8	int:CNOT9
Interaction	PPARG interactions	NCOA3 NCOA6 AGO2 JMJD1C JUND KMT2D FBXO4 KDM6A LRIF1	5.10e-05	307	111	9	int:PPARG
Interaction	CNOT8 interactions	AGO2 TNRC6C ANKRD17 YTHDF2 YTHDF3	5.51e-05	74	111	5	int:CNOT8
Interaction	YTHDF2 interactions	AGO2 OGT TNRC6C YTHDF1 EIF4G2 ANKRD17 YTHDF2 YTHDF3 VCAM1	5.77e-05	312	111	9	int:YTHDF2
Interaction	CNOT2 interactions	AGO2 TNRC6C JMJD1C YTHDF1 ANKRD17 YTHDF2 YTHDF3	5.85e-05	178	111	7	int:CNOT2
Interaction	ZFP36 interactions	ARHGAP32 AGO2 TNRC6C YTHDF1 ANKRD17 YTHDF2 YTHDF3	6.50e-05	181	111	7	int:ZFP36
Interaction	YTHDF3 interactions	AGO2 TNRC6C ITFG1 YTHDF1 EIF4G2 ANKRD17 YTHDF2 YTHDF3	6.58e-05	246	111	8	int:YTHDF3
Interaction	ALG13 interactions	NCOA3 JMJD1C YTHDF1 KMT2D RAVER2 YTHDF2 YTHDF3	6.96e-05	183	111	7	int:ALG13
Interaction	SMAP2 interactions	AGO2 TNRC6C SLC22A12 YTHDF1 YTHDF2 YTHDF3 VCAM1	8.53e-05	189	111	7	int:SMAP2
Interaction	ZYX interactions	CCP110 ARHGAP32 OGT ANK2 GART TLN2 YTHDF2 YTHDF3 VCAM1	8.67e-05	329	111	9	int:ZYX
Interaction	QPRT interactions	ADNP JMJD1C RAVER2 EIF4G2 ANKRD17	1.01e-04	84	111	5	int:QPRT
Interaction	KLF5 interactions	TET2 NCOA3 NCOA6 OGT KMT2D KDM6A YTHDF3	1.04e-04	195	111	7	int:KLF5
Interaction	CNOT7 interactions	AGO2 TNRC6C YTHDF1 ANKRD17 YTHDF2 YTHDF3	1.26e-04	140	111	6	int:CNOT7
Interaction	RORB interactions	NCOA3 NCOA6 ZNF587 ZNF417	1.30e-04	47	111	4	int:RORB
Interaction	CNOT10 interactions	AGO2 TNRC6C YTHDF1 ANKRD17 YTHDF2 YTHDF3	1.31e-04	141	111	6	int:CNOT10
Interaction	TOP3B interactions	NCOA6 AGO2 FRYL ANKLE1 TNRC6C ZZEF1 PRAG1 TIAM2 YTHDF1 JUND SEPHS2 KMT2D KANSL1 FANCI ANKRD17 TLN2 DEPDC5 IQGAP3 YTHDF2 YTHDF3	1.41e-04	1470	111	20	int:TOP3B
Interaction	HCFC2 interactions	NCOA6 OGT KMT2D KANSL1 KDM6A	1.56e-04	92	111	5	int:HCFC2
Interaction	CPEB1 interactions	AGO2 TNRC6C YTHDF1 ANKRD17 YTHDF2 YTHDF3	1.58e-04	146	111	6	int:CPEB1
Interaction	CNOT6L interactions	AGO2 TNRC6C ANKRD17 YTHDF2 YTHDF3	1.64e-04	93	111	5	int:CNOT6L
Interaction	BOD1L1 interactions	NCOA6 OGT ADNP KMT2D MTBP KDM6A	1.77e-04	149	111	6	int:BOD1L1
Interaction	PAGR1 interactions	NCOA6 KMT2D QDPR KDM6A	1.78e-04	51	111	4	int:PAGR1
Interaction	SOX17 interactions	NCOA3 NCOA6 CHD7 KMT2D KDM6A	1.81e-04	95	111	5	int:SOX17
Interaction	ZC3H7A interactions	AGO2 GART TNRC6C YTHDF1 ANKRD17 YTHDF2 YTHDF3	1.90e-04	215	111	7	int:ZC3H7A
Interaction	RBBP5 interactions	NCOA6 AGO2 OGT CHD7 KMT2D KANSL1 FANCI KDM6A	1.91e-04	287	111	8	int:RBBP5
Interaction	SOX9 interactions	NCOA3 NCOA6 CHD7 KMT2D KDM6A	1.99e-04	97	111	5	int:SOX9
Interaction	AGO3 interactions	AGO2 TNRC6C YTHDF1 ANKRD17 YTHDF2 YTHDF3	2.04e-04	153	111	6	int:AGO3
Interaction	MYL4 interactions	AGO2 IQGAP3 VCAM1	2.32e-04	22	111	3	int:MYL4
Interaction	FUBP3 interactions	AGO2 OGT TNRC6C YTHDF1 ANKRD17 YTHDF2 YTHDF3 VCAM1	2.41e-04	297	111	8	int:FUBP3
Interaction	TPRX2 interactions	NCOA6 OGT KMT2D KDM6A	2.57e-04	56	111	4	int:TPRX2
Interaction	NR3C1 interactions	JCAD NCOA3 NCOA6 ARHGAP32 TBRG4 ABCA4 CHD7 FOXJ3 JMJD1C MEPE KMT2D ANKRD17 KDM6A MAML3 LRIF1	2.91e-04	974	111	15	int:NR3C1
Interaction	GARRE1 interactions	ARHGAP32 AGO2 TNRC6C ANKRD17 YTHDF2 YTHDF3	3.27e-04	167	111	6	int:GARRE1
Interaction	FOS interactions	NCOA3 NCOA6 AGO2 JUND KMT2D ANKRD17 VSIG8 KDM6A	3.35e-04	312	111	8	int:FOS
Interaction	LSM14B interactions	AGO2 OGT ITFG1 YTHDF2 YTHDF3	3.43e-04	109	111	5	int:LSM14B
Interaction	YWHAH interactions	TET2 JCAD CCP110 NCOA3 NCOA6 ARHGAP32 OGT FRYL PRAG1 ANKRD27 ANKRD17 MTBP NUB1 SUCO UTRN YTHDF2	3.48e-04	1102	111	16	int:YWHAH
Interaction	SETD1A interactions	NCOA6 OGT EDA KMT2D KANSL1 KDM6A	3.60e-04	170	111	6	int:SETD1A
Interaction	UBAP2 interactions	YTHDF1 ZNF34 ASB13 ANKRD17 YTHDF2 YTHDF3	3.60e-04	170	111	6	int:UBAP2
Interaction	EGR2 interactions	TET2 NCOA3 NCOA6 CHD7 KMT2D KDM6A	3.71e-04	171	111	6	int:EGR2
Interaction	HIF1AN interactions	NCOA3 ANK2 ANK3 ANKRD27 ASB13 RAVER2 ANKRD17 TLN2	3.72e-04	317	111	8	int:HIF1AN
Interaction	PAX8 interactions	TET2 NCOA3 CHD7 KMT2D KDM6A	3.73e-04	111	111	5	int:PAX8
Interaction	TBR1 interactions	TET2 NCOA3 CHD7 KMT2D KDM6A	4.05e-04	113	111	5	int:TBR1
Interaction	BSND interactions	CCP110 TBRG4 ANK3 IQGAP3	4.29e-04	64	111	4	int:BSND
Interaction	MAFA interactions	NCOA6 KMT2D KDM6A	4.32e-04	27	111	3	int:MAFA
Interaction	ELF4 interactions	KMT2D KANSL1 FBXO4 KDM6A LRIF1	4.39e-04	115	111	5	int:ELF4
Interaction	TBXT interactions	NCOA3 NCOA6 CHD7 KMT2D KDM6A	4.57e-04	116	111	5	int:TBXT
Cytoband	19q13.43	ZNF776 ZNF587 ZNF417 NLRP8	6.85e-05	87	114	4	19q13.43
Cytoband	6q24	FBXO30 UTRN	1.69e-04	8	114	2	6q24
GeneFamily	Ankyrin repeat domain containing	TRPA1 ANK2 ANK3 ANKLE1 ANKRD27 ASB13 ANKRD17 POTEI POTEA AGAP7P	9.84e-08	242	79	10	403
GeneFamily	Ataxins\|Trinucleotide repeat containing	NCOA3 TNRC6C KMT2D MAML3	3.98e-06	25	79	4	775
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	ZSWIM2 ZZEF1 UTRN	6.25e-05	18	79	3	91
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	SP3 ZNF613 ZNF25 ZXDA ZNF587B ZNF34 ZBTB49 ZNF776 GLI4 ZNF587 ZNF81 ZNF417	6.25e-05	718	79	12	28
GeneFamily	Cyclins\|F-boxes other	FBXO30 FBXO8 FBXO4	6.55e-04	39	79	3	560
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEI POTEA	1.43e-03	13	79	2	685
GeneFamily	PHD finger proteins\|Lysine demethylases	JMJD1C KDM6A	4.89e-03	24	79	2	485
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 FRYL JMJD1C JUND KANSL1 NUB1 UTRN	8.50e-07	200	114	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD AGO2 FOXJ3 JMJD1C FBXO30 UTRN	8.22e-06	185	114	6	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	NCOA3 ITFG2 KANSL1 TLN2 UTRN MAML3	8.48e-06	186	114	6	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	NCOA3 ITFG2 KANSL1 TLN2 UTRN MAML3	8.48e-06	186	114	6	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	JMJD1C KANSL1 ANKRD17 UTRN KDM6A MAML3	1.05e-05	193	114	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 ANK2 ANK3 TIAM2 ITFG1 SLC24A2	1.08e-05	194	114	6	ba529c051f248d29f4222f4bc9801ba233859093
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	JCAD ADAMTSL1 CD93 PLAT UTRN VCAM1	1.14e-05	196	114	6	ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TET2 ANK3 DNAJB9 FBXO30 TLN2 VCAM1	1.18e-05	197	114	6	5bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANK3 MYO5B LAMA3 CHD7 ECEL1 UTRN	1.18e-05	197	114	6	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	LV-09._Endothelium_I\|LV / Chamber and Cluster_Paper	JCAD NCOA3 TMTC2 FRYL PRAG1 UTRN	1.18e-05	197	114	6	f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ANK3 TMTC2 KANSL1 KDM6A MAML3	1.21e-05	198	114	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ANK3 KANSL1 UTRN KDM6A MAML3	1.25e-05	199	114	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Macroglial-Oligodendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CCP110 ANK3 TMTC2 FRYL SLC24A2 QDPR	1.28e-05	200	114	6	4dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ANK3 MYO5B TMTC2 RAVER2 MAML3	1.28e-05	200	114	6	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Macroglial-Oligodendrocytes-OPALIN--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CCP110 ANK3 TMTC2 FRYL SLC24A2 QDPR	1.28e-05	200	114	6	26b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCell	Macroglial-Oligodendrocytes-OPALIN---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CCP110 ANK3 TMTC2 FRYL SLC24A2 QDPR	1.28e-05	200	114	6	1314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCell	Macroglial-Oligodendrocytes-OPALIN-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CCP110 ANK3 TMTC2 FRYL SLC24A2 QDPR	1.28e-05	200	114	6	8b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCell	Macroglial-Oligodendrocytes-OPALIN----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CCP110 ANK3 TMTC2 FRYL SLC24A2 QDPR	1.28e-05	200	114	6	272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCell	Macroglial-Oligodendrocytes-OPALIN\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CCP110 ANK3 TMTC2 FRYL SLC24A2 QDPR	1.28e-05	200	114	6	5f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	AGO2 OGT KMT2D ZNF587 KDM6A	2.55e-05	135	114	5	ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell	LPS-antiTNF-Endothelial-Epi-like-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWA3A MYO5B PPFIA4 GAL3ST4 UTP20	4.22e-05	150	114	5	9cb3332924bd67c966873343c14445e30d3f384f
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF776 GZMH KCNK10 ZNF417 IQGAP3	5.74e-05	160	114	5	1a9329d8183296f36928bd9e96f10db9f04ce326
ToppCell	droplet-Thymus-nan-21m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 PPFIA4 EDA C6 VCAM1	5.91e-05	161	114	5	441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCell	droplet-Spleen-SPLEEN-1m-Myeloid-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 ANK2 PPFIA4 C6 VCAM1	7.43e-05	169	114	5	3f8aa6d2f9aa060ae1a0ea3eb47e794099fc2c2c
ToppCell	droplet-Spleen-SPLEEN-1m-Myeloid\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 ANK2 PPFIA4 C6 VCAM1	7.43e-05	169	114	5	26de495c7562e0740689d0f78e803698e3e793db
ToppCell	droplet-Spleen-SPLEEN-1m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA3A STAB2 ANK2 PPFIA4 VCAM1	7.64e-05	170	114	5	670027daec5a10dfa12246f1497b58db21d32a22
ToppCell	CV-Mild-7\|Mild / Virus stimulation, Condition and Cluster	TET2 CCP110 ZNF776 FANCI ZNF81	8.30e-05	173	114	5	c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 FRYL PLAT UTRN VCAM1	1.00e-04	180	114	5	67c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	OGT ANK3 JMJD1C KANSL1 KDM6A	1.03e-04	181	114	5	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 FRYL PLAT UTRN VCAM1	1.05e-04	182	114	5	ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 FRYL PLAT UTRN VCAM1	1.05e-04	182	114	5	47ff6b4002a4167412c79210651316d1342503f9
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 JMJD1C JUND UTRN KDM6A	1.11e-04	184	114	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	saliva-Severe-critical_progression_d28-40\|saliva / Compartment, severity and other cell annotations on 10x 3' data (130k)	TET2 NCOA6 JMJD1C NUB1 TOR1AIP1	1.17e-04	186	114	5	0095560ca776b01aa473ad4d6015ed78fc93ff51
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LAMA3 JMJD1C CD93 JUND ASTN1	1.17e-04	186	114	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPA1 FRYL PLAT UTRN VCAM1	1.20e-04	187	114	5	7170694a1b86fe8d84d96c880ffe57af09bdc026
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	JMJD1C KANSL1 SUCO UTRN KDM6A	1.23e-04	188	114	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	JCAD ADAMTSL1 CD93 PLAT VCAM1	1.26e-04	189	114	5	c121817ddad164e9cfe382c43d0cbc9215508d02
ToppCell	Endothelial-A-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	JCAD ADAMTSL1 CD93 PLAT VCAM1	1.26e-04	189	114	5	04b565855f58ca0f343904d04be657b66e109076
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	OGT JUND KANSL1 GZMH UTRN	1.26e-04	189	114	5	0e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 TMTC2 KANSL1 ANKRD17 UTRN	1.26e-04	189	114	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TET2 JMJD1C CD93 JUND UTRN	1.26e-04	189	114	5	55aba1ebc012006a5db3ff9c92589cb3d9f7c68a
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD LAMA3 GAL3ST4 CD93 PLAT	1.29e-04	190	114	5	9d5242759546be0089981ef1877e4ed5f81face5
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	JCAD ADAMTSL1 CD93 PLAT UTRN	1.32e-04	191	114	5	04c7aa2e39fdd08ca24c10d43b29a5e41a73b9e0
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	JCAD ADAMTSL1 CD93 PLAT UTRN	1.32e-04	191	114	5	db8dd6bbba803585bdd6a55d5c403d383f2e9acf
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA3 FRYL JMJD1C JUND VCAM1	1.32e-04	191	114	5	8691eba35793e4e90f93d50c2145847ee51289f7
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	JCAD ADAMTSL1 CD93 PLAT UTRN	1.35e-04	192	114	5	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	PRAG1 EDA KANSL1 UTRN KDM6A	1.35e-04	192	114	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMTC2 CD93 PLAT C6 VCAM1	1.35e-04	192	114	5	52acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	OGT ANK3 JMJD1C KANSL1 KDM6A	1.35e-04	192	114	5	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTSL1 ANK3 MYO5B LAMA3 SLCO4C1	1.35e-04	192	114	5	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	MS-Treg-exh_CD4\|MS / Condition, Cell_class and T cell subcluster	GART SEPHS2 ZNF587 DEPDC5 VSIG8	1.35e-04	192	114	5	c6722bf142c84ccedd99c1a3344085aecb4cbab4
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	JCAD ADAMTSL1 CD93 PLAT UTRN	1.39e-04	193	114	5	3a9fe4e709c09ec787c71bdd6b58a71c419896de
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD ADAMTSL1 CD93 PLAT VCAM1	1.39e-04	193	114	5	1f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell	RV-09._Endothelium_I\|RV / Chamber and Cluster_Paper	NCOA3 TMTC2 FRYL PRAG1 UTRN	1.42e-04	194	114	5	7b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCell	LV-09._Endothelium_I\|World / Chamber and Cluster_Paper	NCOA3 TMTC2 FRYL PRAG1 UTRN	1.45e-04	195	114	5	19e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCell	COVID-19-Heart-EC_1\|Heart / Disease (COVID-19 only), tissue and cell type	JCAD FRYL PRAG1 CD93 UTRN	1.45e-04	195	114	5	50a193475db1bb1e05b8590225a553688c372c14
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD ADAMTSL1 CD93 PLAT UTRN	1.49e-04	196	114	5	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TET2 JMJD1C CD93 JUND YTHDF3	1.49e-04	196	114	5	01cea0bb0b938d0986fd2ddae06597b8af1768ee
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TET2 ANK3 DNAJB9 TLN2 VCAM1	1.49e-04	196	114	5	97ac47daf5bb07fa5dda3976e1ae402750f959b5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CD93 SLC24A2 PLAT UTRN	1.49e-04	196	114	5	145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJB9 JMJD1C FBXO30 EIF4G2 UTRN	1.49e-04	196	114	5	151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD ADAMTSL1 CD93 PLAT UTRN	1.49e-04	196	114	5	e224338490691d92c1f70b57112fabdcc92b06a9
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	NCOA3 GHRL ANK2 LRRCC1 VCAM1	1.53e-04	197	114	5	4edf043e8f586fd375f56485841fe992a18bf853
ToppCell	facs-Brain_Non-Myeloid\|facs / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD ANK3 SLC24A2 PLAT UTRN	1.53e-04	197	114	5	a1f7eec1aca03432caa8fe817ff6d24b29d4062d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD ADAMTSL1 CD93 PLAT UTRN	1.53e-04	197	114	5	c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCell	Control_saline-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	ARHGAP32 ANK3 LAMA3 ECEL1 UTRN	1.53e-04	197	114	5	44a59dfb889577b3160a5b13ada1276771a00241
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD ADAMTSL1 CD93 PLAT UTRN	1.53e-04	197	114	5	2844dbcd0a673ed81c99920aa45858651a00736d
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ANK3 MYO5B LAMA3 TMTC2	1.60e-04	199	114	5	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	OGT ANK3 FRYL KANSL1 UTRN	1.60e-04	199	114	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	T_cells-CCR7+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ANK3 CHD7 DNAJB9 JMJD1C JUND	1.60e-04	199	114	5	467820d6abe3024d9d655b9672c2f9cdc1303db3
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ANK3 MYO5B LAMA3 TMTC2	1.60e-04	199	114	5	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	MS-IIF-Lymphocyte-T/NK-ILC\|IIF / Disease, condition lineage and cell class	ANKRD27 ASB13 LRRCC1 DECR2 ZNF81	1.64e-04	200	114	5	edb0b252e6ff9824908d1ff7d0d42710b00949c8
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ANK3 MYO5B RAVER2 MAML3	1.64e-04	200	114	5	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
Computational	Neighborhood of CSNK1A1	FOXJ3 SENP6 ANKRD17 TOR1AIP1	5.15e-05	36	62	4	GCM_CSNK1A1
Disease	Abnormality of refraction	JCAD ARHGAP32 ADAMTSL1 ABCA4 ANK3 MYO5B ZZEF1 SLC24A2 ECEL1 C6 UTRN TOR1AIP1	8.25e-06	673	110	12	HP_0000539
Disease	Kabuki syndrome 1	KMT2D KDM6A	1.38e-05	2	110	2	cv:CN030661
Disease	Kabuki syndrome (is_implicated_in)	KMT2D KDM6A	1.38e-05	2	110	2	DOID:0060473 (is_implicated_in)
Disease	KABUKI SYNDROME 1	KMT2D KDM6A	1.38e-05	2	110	2	147920
Disease	Kabuki syndrome (implicated_via_orthology)	KMT2D KDM6A	4.12e-05	3	110	2	DOID:0060473 (implicated_via_orthology)
Disease	disease of metabolism (implicated_via_orthology)	YTHDF1 YTHDF2 YTHDF3	6.38e-05	21	110	3	DOID:0014667 (implicated_via_orthology)
Disease	Kabuki make-up syndrome	KMT2D KDM6A	8.22e-05	4	110	2	C0796004
Disease	prostate carcinoma	TET2 SP3 ADAMTSL1 POLR1A ANK2 TMTC2 CHD7 ADNP AGAP7P TOR1AIP1 MAML3 LRIF1	1.25e-04	891	110	12	EFO_0001663
Disease	lung small cell carcinoma (is_implicated_in)	LAMA3 KMT2D KDM6A	1.54e-04	28	110	3	DOID:5409 (is_implicated_in)
Disease	Leukemia, Myelomonocytic, Chronic	TET2 KDM6A	2.05e-04	6	110	2	C0023480
Disease	refractive error	JCAD ADAMTSL1 ANK3 MYO5B CHD7 ZZEF1 ECEL1	2.27e-04	326	110	7	MONDO_0004892
Disease	coronary artery calcification	ANK3 ZSWIM2 ZBTB49 ZNF776 EIF4G2 KCNK10 UTP20 ASTN1	2.90e-04	450	110	8	EFO_0004723
Disease	diabetic neuropathy (is_marker_for)	PLAT VCAM1	3.80e-04	8	110	2	DOID:9743 (is_marker_for)
Disease	Congenital small ears	CHD7 KMT2D KDM6A	4.85e-04	41	110	3	C0152423
Disease	Adenoid Cystic Carcinoma	JMJD1C KANSL1 KDM6A MAML3	5.44e-04	100	110	4	C0010606
Disease	tyrosine measurement	ADAMTSL1 PRAG1 JMJD1C DEPDC5	6.31e-04	104	110	4	EFO_0005058
Disease	esophagus squamous cell carcinoma (is_implicated_in)	TET2 KMT2D KDM6A	6.38e-04	45	110	3	DOID:3748 (is_implicated_in)
Disease	age at menopause	FRYL CHD7 ADNP SLC18A1 FANCI LRIF1	9.62e-04	302	110	6	EFO_0004704
Disease	Fetal Alcohol Syndrome	ANK3 ADNP	1.81e-03	17	110	2	C0015923
Disease	peritonsillar abscess	TET2 PRAG1	2.03e-03	18	110	2	EFO_0007429
Disease	Prostatic Neoplasms	TET2 NCOA3 STAB2 CHD7 KMT2D SENP6 M6PR KDM6A	2.19e-03	616	110	8	C0033578
Disease	Malignant neoplasm of prostate	TET2 NCOA3 STAB2 CHD7 KMT2D SENP6 M6PR KDM6A	2.19e-03	616	110	8	C0376358
Disease	Alzheimer disease, educational attainment	TET2 JMJD1C ERCC8 KANSL1 MAML3	2.37e-03	247	110	5	EFO_0011015, MONDO_0004975
Disease	esophagus squamous cell carcinoma (is_marker_for)	TET2 KMT2D KDM6A	2.70e-03	74	110	3	DOID:3748 (is_marker_for)
Disease	intellectual disability (implicated_via_orthology)	ANK2 PREB KANSL1	2.80e-03	75	110	3	DOID:1059 (implicated_via_orthology)
Disease	Liver carcinoma	STAB2 FANCI MTBP DEPDC5 IQGAP3 YTHDF2 VCAM1	2.95e-03	507	110	7	C2239176
Disease	peptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease	DEPDC5 MAML3	3.60e-03	24	110	2	EFO_0003948, EFO_0009923, MONDO_0004247

Protein segments in the cluster

Peptide	Gene	Start	Entry
HLQQNNYGVKSVGQG	ADNP	326	Q9H2P0
EALGIQTLTNQKQGH	ANKLE1	556	Q8NAG6
QGSGLHQVSKRQQVD	CCDC169	156	A6NNP5
NQITAFLGHNGAGKT	ABCA4	956	P78363
NAGANVNAAKLHETA	ASB13	171	Q8WXK3
QGSSINVTLGAHNIK	GZMH	66	P20718
GIGSGVNFQLNNQHK	FBXO4	216	Q9UKT5
NHCNQNGGNLATVKS	CD93	51	Q9NPY3
NSGSANGIHQQDKAQ	CLIP2	1026	Q9UDT6
SKGANVNRTTANNDH	ANKRD17	651	O75179
AVHQLCQSLAGKNSG	QDPR	156	P09417
DAHKNFAQNRGAGNT	CHD7	2126	Q9P2D1
GQNQNTGSKKRFENH	DNAJB9	126	Q9UBS3
NNHSKEVAAGQVLKG	ASTN1	741	O14525
SGQSNGRDHQALAKA	AGO2	831	Q9UKV8
TSGAHRQALAVNQGQ	C17orf113	81	A0A1B0GUU1
AAGSLLVGHHKQQQS	RAVER2	536	Q9HCJ3
RGNVQLAAQTLAHNG	NUB1	516	Q9Y5A7
LQHGAKPNATTANGN	ANK2	781	Q01484
QHGASINASNNKGNT	ANKRD27	831	Q96NW4
INASNNKGNTALHEA	ANKRD27	836	Q96NW4
EQQAAVHGGKSSAQS	DEPDC5	1056	O75140
KHLKVGQQGDSNNNL	FANCI	291	Q9NVI1
KTHQGENNGLANSIR	LAMA3	2011	Q16787
NVATETQLKGGQHSQ	LRIF1	271	Q5T3J3
GTNSLNKQHNILTYG	MAML3	586	Q96JK9
VNSHLLGNVGINNQK	BLZF1	306	Q9H2G9
NRVDAGSQNAHQGKV	MEPE	356	Q9NQ76
NLNSNLGHVVADAKG	HHIPL1	166	Q96JK4
TDLGNNLQGNGHLKT	NLRP8	806	Q86W28
LAGAHQQVSALQQGA	PPFIA4	186	O75335
QGEHVLNSQNKGKSR	JCAD	216	Q9P266
TINKANSVGNGQASQ	JMJD1C	1526	Q15652
KNRETNAVHVNVGAG	KIAA1109	401	Q2LD37
DLHKQNQLGAGAAAA	JUND	146	P17535
SQHLQAAGSGIQNQN	KDM6A	666	O15550
ALQTHKHQNGIFSNG	ADAMTSL1	991	Q8N6G6
AINTKEQNFLQGHGN	CFAP52	51	Q8N1V2
QGNQGQHHLNSQVSL	FAM205A	246	Q6ZU69
NKNQDTQHGVANGAS	FRYL	656	O94915
GQALQVHAGSAKAAV	DECR2	171	Q9NUI1
SNISNTNHRKQVQGG	FBXO8	36	Q9NRD0
NNGNANILIAANGTK	KANSL1	36	Q7Z3B3
LNKHGQGASEDNIIN	KCNK10	431	P57789
AATNIGLNNSHKVQG	ARHGAP32	1326	A7KAX9
NAQAGHKQGLSTVSN	GAL3ST4	331	Q96RP7
KSQGLSQLYHNQSQG	EIF4G2	431	P78344
NQRVNGKHTLGENIA	ECEL1	661	O95672
LQHAAAGKAFSGQSQ	IQGAP3	1216	Q86VI3
NKNVSTHLIGNIKQG	ITFG2	251	Q969R8
AVESANTAHNGKVNG	ERCC8	236	Q13216
LQSDISAGHFGVNNK	NCOA6	891	Q14686
VHLQGQGSAIQVKND	EDA	251	Q92838
KDLTSLGHNENQQGS	C6	256	P13671
LSGVQYQQHSQALGK	GHRL	86	Q9UBU3
RAAIQKSDATQNAHG	FOXJ3	36	Q9UPW0
CGKAFGQSSQLIQHQ	GLI4	356	P10075
VHITKNRNGGGSLNN	AGAP7P	176	Q5VUJ5
NQNGLNALHLASKEG	ANK3	71	Q12955
GKSNQVCQSSGNHLE	CCP110	456	O43303
QNLHGDSKQSNLTNG	FBXO30	301	Q8TB52
QNQAVKKATHGTLGN	SLC22A12	531	Q96S37
AENQFGKANGTTHLV	CNTN3	481	Q9P232
HIQFLGGKSQKDQNT	TBRG4	436	Q969Z0
ANQINGSFALNLIHG	MTBP	421	Q96DY7
NGLATTQINNKAATG	OGT	806	O15294
QKHGSNNVGLSENLT	POTEA	346	Q6S8J7
HVLQTGQINQKLGVS	UTP20	1661	O75691
AHQSSVGSVLQAGNQ	UTRN	361	P46939
KLDNGNLQHLSGNAT	VCAM1	261	P19320
AQGNFTGHTKKTNGN	TNRC6C	6	Q9HCJ0
GKNKHSSGQQNLNTI	CRCP	31	O75575
NNLLGSQGAHVKNVC	POLR1A	171	O95602
NGNLSHNIEGAEAQT	SLC24A2	436	Q9UI40
GSHLGTKQQVFQGTN	NCOA3	821	Q9Y6Q9
HTLKEQTNSGNLGKQ	SHLD3	106	Q6ZNX1
ALHLASANGNSGVVK	POTEI	176	P0CG38
LHQSNTSFIKLNNNG	CLCA4	16	Q14CN2
QAHQQQGNKAEKAGS	PREB	96	Q9HCU5
KGQGNKVSVQNGSIH	YTHDF3	11	Q7Z739
GILGHSQNLAKQQRN	SEPHS2	321	Q99611
AQNPSAQALGLGKHN	PLAT	251	P00750
FHSSINQGLNNGDLV	VSIG8	211	P0DPA2
NNGKATPLHLAVQNG	TRPA1	236	O75762
SNGFKNGQNAAVVHR	TOR1AIP1	466	Q5JTV8
QGSKNHSNTITGAKQ	TIAM2	11	Q8IVF5
AGNHTSGAGLVQINK	M6PR	81	P20645
GTAEIQAGKTSQAHQ	SLCO4C1	341	Q6ZQN7
QQQQHGNGAVAAAAA	SP3	36	Q02447
IHGVQASGQNISQQA	SP3	421	Q02447
TVTNGKQNANGHSCL	TMTC2	341	Q8N394
KSFGQKGNLIQHQQG	ZNF587	331	Q96SQ5
KSFGQKGNLIQHQQG	ZNF417	331	Q8TAU3
GKSFGQKGNLVQHQR	ZNF417	386	Q8TAU3
IHQNSGGQKSQNTGL	SENP6	256	Q9GZR1
GDNAATNGVIHIINK	STAB2	1111	Q8WWQ8
NGNLVHGSNQKESVF	SUCO	901	Q9UBS9
AKIEHAAAAQGQGQV	PRAG1	431	Q86YV5
QINGSVLKNGSLTNH	GART	786	P22102
KNSAVNGQAHQSVSN	ZSWIM2	396	Q8NEG5
QKSSLIQHQQFHTGG	ZNF587B	281	E7ETH6
QAGNSRNGELTKHQK	ZNF25	96	P17030
NAAGNHGSQKERNLI	ZXDA	776	P98168
GGNSVNTNSQFIKHQ	ZNF613	181	Q6PF04
KNSSGANLQGELSHI	ZZEF1	141	O43149
QQQFNRTGKAEHGSV	TLN2	436	Q9Y4G6
NICGKHFSQAGNLQT	ZBTB49	426	Q6ZSB9
KAGQHSQAVADLQAA	TTC37	576	Q6PGP7
KNGSAGQLSQSAHLA	ITFG1	481	Q8TB96
GQSQGTVDQHLQFQK	TET2	641	Q6N021
GQNSDNGLLVTHVNQ	VWA3A	56	A6NCI4
NKVQNGSVHQKDGLN	YTHDF2	16	Q9Y5A9
NLDKTIGHGQVFTQN	ZNF81	216	P51508
TKGQDNKVQNGSLHQ	YTHDF1	11	Q9BYJ9
CGKGFTQSSNLIQHQ	ZNF34	396	Q8IZ26
EAISAHKNNCLQGTG	SLC18A1	116	P54219
DILHQGTQHNQKLNG	ZNF776	101	Q68DI1
QQQQVSLLHTAGGGS	KMT2D	4101	O14686
HELAQQGSSLAQNRG	LRRCC1	771	Q9C099
KAVADQATQNNSSHG	MYO5B	1221	Q9ULV0