Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL3A1 HSPG2 FRAS1 FN1 LAMA1 HMCN2 MUC17 VCAN	3.21e-06	188	95	8	GO:0005201
GeneOntologyMolecularFunction	calcium ion binding	HSPG2 STAB2 PKD1L2 F12 TBC1D9 GSN FAT1 PROZ HMCN2 VCAN LRP1 C1S	2.24e-04	749	95	12	GO:0005509
GeneOntologyMolecularFunction	protease binding	COL3A1 HSPG2 FN1 XIAP CNTNAP2 LRP1	2.28e-04	181	95	6	GO:0002020
GeneOntologyBiologicalProcess	extracellular matrix organization	COL3A1 HSPG2 ABL1 FN1 LAMA1 POMGNT1 HPSE2 ADAMTSL3 GSN FSHR LRP1	1.78e-06	377	98	11	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	COL3A1 HSPG2 ABL1 FN1 LAMA1 POMGNT1 HPSE2 ADAMTSL3 GSN FSHR LRP1	1.82e-06	378	98	11	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	COL3A1 HSPG2 ABL1 FN1 LAMA1 POMGNT1 HPSE2 ADAMTSL3 GSN FSHR LRP1	1.87e-06	379	98	11	GO:0045229
GeneOntologyBiologicalProcess	regulation of protein processing	XIAP F12 GSN CTSZ CHAC1	4.46e-05	82	98	5	GO:0070613
GeneOntologyBiologicalProcess	basement membrane organization	COL3A1 LAMA1 POMGNT1 FSHR	5.13e-05	43	98	4	GO:0071711
GeneOntologyBiologicalProcess	regulation of protein maturation	XIAP F12 GSN CTSZ CHAC1	5.61e-05	86	98	5	GO:1903317
GeneOntologyBiologicalProcess	axonogenesis	HSPG2 ABL1 FN1 LAMA1 LGR4 ADARB1 CYFIP1 HMCN2 CNTNAP2 LRP1 SEPTIN7	7.81e-05	566	98	11	GO:0007409
GeneOntologyBiologicalProcess	regulation of amyloid-beta clearance	PLA2G3 IFNGR1 LRP1	1.12e-04	20	98	3	GO:1900221
GeneOntologyCellularComponent	extracellular matrix	COL3A1 HSPG2 LAMB4 FRAS1 FN1 LAMA1 HPSE2 CELA2B ADAMTSL3 F12 FCGBP HMCN2 MUC17 VCAN CTSZ	3.94e-07	656	98	15	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL3A1 HSPG2 LAMB4 FRAS1 FN1 LAMA1 HPSE2 CELA2B ADAMTSL3 F12 FCGBP HMCN2 MUC17 VCAN CTSZ	4.09e-07	658	98	15	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL3A1 HSPG2 LAMB4 FRAS1 FN1 LAMA1 CELA2B F12 HMCN2 MUC17 VCAN CTSZ	6.99e-06	530	98	12	GO:0062023
GeneOntologyCellularComponent	basement membrane	HSPG2 LAMB4 FRAS1 FN1 LAMA1 HMCN2	2.37e-05	122	98	6	GO:0005604
GeneOntologyCellularComponent	Golgi lumen	HSPG2 GALNT2 PROZ MUC17 VCAN	1.62e-04	109	98	5	GO:0005796
GeneOntologyCellularComponent	Atg12-Atg5-Atg16 complex	WDFY3 ATG16L2	3.22e-04	6	98	2	GO:0034274
GeneOntologyCellularComponent	neuronal cell body	PCSK2 ABL1 SEZ6L2 RGS12 CYFIP1 HMCN2 CD22 CNTNAP2 LRP1 PPP1R9B WDFY3 SEPTIN7	5.29e-04	835	98	12	GO:0043025
GeneOntologyCellularComponent	somatodendritic compartment	PCSK2 ABL1 SEZ6L2 RGS12 IFNGR1 CYFIP1 HMCN2 CD22 CNTNAP2 LRP1 CNTNAP4 PPP1R9B ABHD13 WDFY3 SEPTIN7	5.79e-04	1228	98	15	GO:0036477
GeneOntologyCellularComponent	cell body	PCSK2 ABL1 SEZ6L2 RGS12 CYFIP1 HMCN2 CD22 CNTNAP2 LRP1 PPP1R9B WDFY3 SEPTIN7	1.34e-03	929	98	12	GO:0044297
MousePheno	abnormal caput epididymis morphology	PLA2G3 LGR4 CEP78 FSHR	3.79e-06	19	81	4	MP:0002660
Domain	EGF-like_dom	HSPG2 FRAS1 STAB2 LAMA1 F12 MEP1A FAT1 FCGBP PROZ HMCN2 MUC17 VCAN CNTNAP2 LRP1 CNTNAP4 C1S	2.20e-13	249	98	16	IPR000742
Domain	EGF_1	HSPG2 LAMB4 STAB2 FN1 LAMA1 F12 MEP1A FAT1 PROZ HMCN2 MUC17 VCAN CNTNAP2 LRP1 CNTNAP4 C1S	3.18e-13	255	98	16	PS00022
Domain	EGF-like_CS	HSPG2 LAMB4 STAB2 FN1 LAMA1 F12 MEP1A FAT1 PROZ HMCN2 MUC17 VCAN CNTNAP2 LRP1 CNTNAP4 C1S	4.55e-13	261	98	16	IPR013032
Domain	EGF_2	HSPG2 LAMB4 STAB2 LAMA1 F12 MEP1A FAT1 PROZ HMCN2 MUC17 VCAN CNTNAP2 LRP1 CNTNAP4 C1S	8.17e-12	265	98	15	PS01186
Domain	EGF	HSPG2 FRAS1 STAB2 LAMA1 F12 MEP1A FAT1 FCGBP PROZ MUC17 VCAN CNTNAP2 LRP1 CNTNAP4	2.16e-11	235	98	14	SM00181
Domain	EGF	HSPG2 STAB2 F12 MEP1A FAT1 PROZ VCAN CNTNAP2 LRP1 CNTNAP4 C1S	5.77e-11	126	98	11	PF00008
Domain	EGF_3	HSPG2 STAB2 F12 MEP1A FAT1 PROZ HMCN2 MUC17 VCAN CNTNAP2 LRP1 CNTNAP4 C1S	2.97e-10	235	98	13	PS50026
Domain	EGF_CA	HSPG2 STAB2 F12 FAT1 PROZ HMCN2 VCAN LRP1 C1S	1.55e-08	122	98	9	SM00179
Domain	EGF-like_Ca-bd_dom	HSPG2 STAB2 F12 FAT1 PROZ HMCN2 VCAN LRP1 C1S	1.79e-08	124	98	9	IPR001881
Domain	LAM_G_DOMAIN	HSPG2 LAMA1 FAT1 CNTNAP2 CNTNAP4	1.57e-06	38	98	5	PS50025
Domain	Laminin_G_2	HSPG2 LAMA1 FAT1 CNTNAP2 CNTNAP4	2.04e-06	40	98	5	PF02210
Domain	ConA-like_dom	HSPG2 MID2 LAMA1 MEP1A BTN3A3 FAT1 CNTNAP2 CNTNAP4 WDFY3	2.27e-06	219	98	9	IPR013320
Domain	LamG	HSPG2 LAMA1 FAT1 CNTNAP2 CNTNAP4	3.31e-06	44	98	5	SM00282
Domain	Galactose-bd-like	PCSK2 LAMA1 CUL9 BTBD9 CNTNAP2 CNTNAP4	1.00e-05	94	98	6	IPR008979
Domain	-	HSPG2 LAMA1 FAT1 CNTNAP2 CNTNAP4 WDFY3	1.07e-05	95	98	6	2.60.120.200
Domain	Laminin_G	HSPG2 LAMA1 FAT1 CNTNAP2 CNTNAP4	1.32e-05	58	98	5	IPR001791
Domain	ASX_HYDROXYL	FAT1 PROZ HMCN2 VCAN LRP1 C1S	1.43e-05	100	98	6	PS00010
Domain	EGF_LAM_2	HSPG2 LAMB4 STAB2 LAMA1	1.76e-05	30	98	4	PS50027
Domain	EGF_LAM_1	HSPG2 LAMB4 STAB2 LAMA1	1.76e-05	30	98	4	PS01248
Domain	Growth_fac_rcpt_	HSPG2 FRAS1 STAB2 LAMA1 FAT1 HMCN2 LRP1	1.81e-05	156	98	7	IPR009030
Domain	Ig-like_fold	IGSF8 HSPG2 FN1 MID2 ADAMTSL3 IFNGR1 BTN3A3 HMCN2 CD22 VCAN SIGLEC1 OSMR CEACAM20 IGSF3	1.85e-05	706	98	14	IPR013783
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT1 PROZ HMCN2 VCAN LRP1 C1S	2.00e-05	106	98	6	IPR000152
Domain	EGF_Lam	HSPG2 LAMB4 STAB2 LAMA1	3.29e-05	35	98	4	SM00180
Domain	-	PCSK2 CUL9 BTBD9 CNTNAP2 CNTNAP4	4.06e-05	73	98	5	2.60.120.260
Domain	-	IGSF8 HSPG2 FN1 MID2 ADAMTSL3 IFNGR1 BTN3A3 CD22 VCAN SIGLEC1 OSMR CEACAM20 IGSF3	4.24e-05	663	98	13	2.60.40.10
Domain	Laminin_EGF	HSPG2 LAMB4 STAB2 LAMA1	4.59e-05	38	98	4	IPR002049
Domain	IG	IGSF8 HSPG2 ADAMTSL3 BTN3A3 HMCN2 CD22 VCAN SIGLEC1 CEACAM20 IGSF3	7.28e-05	421	98	10	SM00409
Domain	Ig_sub	IGSF8 HSPG2 ADAMTSL3 BTN3A3 HMCN2 CD22 VCAN SIGLEC1 CEACAM20 IGSF3	7.28e-05	421	98	10	IPR003599
Domain	EGF_Ca-bd_CS	FAT1 HMCN2 VCAN LRP1 C1S	1.58e-04	97	98	5	IPR018097
Domain	FN1_2	FN1 F12	1.62e-04	4	98	2	PS51091
Domain	fn1	FN1 F12	1.62e-04	4	98	2	PF00039
Domain	Fibronectin_type1	FN1 F12	1.62e-04	4	98	2	IPR000083
Domain	FN1	FN1 F12	1.62e-04	4	98	2	SM00058
Domain	FN1_1	FN1 F12	1.62e-04	4	98	2	PS01253
Domain	EGF_CA	FAT1 HMCN2 VCAN LRP1 C1S	1.74e-04	99	98	5	PS01187
Domain	IGc2	HSPG2 ADAMTSL3 HMCN2 CD22 SIGLEC1 CEACAM20 IGSF3	2.39e-04	235	98	7	SM00408
Domain	Ig_sub2	HSPG2 ADAMTSL3 HMCN2 CD22 SIGLEC1 CEACAM20 IGSF3	2.39e-04	235	98	7	IPR003598
Domain	IG_LIKE	IGSF8 HSPG2 ADAMTSL3 BTN3A3 HMCN2 CD22 VCAN SIGLEC1 CEACAM20 IGSF3	2.55e-04	491	98	10	PS50835
Domain	F5_F8_type_C	BTBD9 CNTNAP2 CNTNAP4	2.62e-04	24	98	3	PF00754
Domain	FA58C	BTBD9 CNTNAP2 CNTNAP4	2.62e-04	24	98	3	IPR000421
Domain	Ig-like_dom	IGSF8 HSPG2 ADAMTSL3 BTN3A3 HMCN2 CD22 VCAN SIGLEC1 CEACAM20 IGSF3	3.09e-04	503	98	10	IPR007110
Domain	BRCT	ENGASE SLF1 NBN	3.34e-04	26	98	3	PS50172
Domain	Gphrmn_rcpt_fam	LGR4 FSHR	4.03e-04	6	98	2	IPR002131
Domain	BRCT_dom	ENGASE SLF1 NBN	4.17e-04	28	98	3	IPR001357
Domain	V-set	IGSF8 HSPG2 BTN3A3 VCAN SIGLEC1 IGSF3	4.19e-04	184	98	6	PF07686
Domain	Ig_I-set	HSPG2 ADAMTSL3 HMCN2 CD22 SIGLEC1 CEACAM20	4.97e-04	190	98	6	IPR013098
Domain	I-set	HSPG2 ADAMTSL3 HMCN2 CD22 SIGLEC1 CEACAM20	4.97e-04	190	98	6	PF07679
Domain	Ig_V-set	IGSF8 HSPG2 BTN3A3 VCAN SIGLEC1 IGSF3	6.33e-04	199	98	6	IPR013106
Domain	LAMININ_IVA	HSPG2 LAMA1	7.48e-04	8	98	2	PS51115
Domain	Laminin_B	HSPG2 LAMA1	7.48e-04	8	98	2	PF00052
Domain	LamB	HSPG2 LAMA1	7.48e-04	8	98	2	SM00281
Domain	Laminin_IV	HSPG2 LAMA1	7.48e-04	8	98	2	IPR000034
Domain	Laminin_EGF	HSPG2 LAMB4 LAMA1	8.12e-04	35	98	3	PF00053
Domain	VWC	COL3A1 FRAS1 FCGBP	1.03e-03	38	98	3	SM00214
Domain	EGF_CA	FAT1 HMCN2 LRP1 C1S	1.09e-03	86	98	4	PF07645
Domain	VWF_dom	COL3A1 FRAS1 FCGBP	1.39e-03	42	98	3	IPR001007
Domain	Laminin_G_1	HSPG2 LAMA1	1.45e-03	11	98	2	PF00054
Domain	ZnF_UBP	USP49 USP44	1.45e-03	11	98	2	SM00290
Domain	Link_dom	STAB2 VCAN	2.05e-03	13	98	2	IPR000538
Domain	Xlink	STAB2 VCAN	2.05e-03	13	98	2	PF00193
Domain	LINK_2	STAB2 VCAN	2.05e-03	13	98	2	PS50963
Domain	LINK	STAB2 VCAN	2.05e-03	13	98	2	SM00445
Domain	-	FN1 F12	2.05e-03	13	98	2	2.10.10.10
Domain	LINK_1	STAB2 VCAN	2.05e-03	13	98	2	PS01241
Domain	FN_type2_col-bd	FN1 F12	2.38e-03	14	98	2	IPR000562
Domain	FN2_2	FN1 F12	2.38e-03	14	98	2	PS51092
Domain	Znf_UBP	USP49 USP44	2.38e-03	14	98	2	IPR001607
Domain	zf-UBP	USP49 USP44	2.38e-03	14	98	2	PF02148
Domain	FN2_1	FN1 F12	2.38e-03	14	98	2	PS00023
Domain	SEA	HSPG2 MUC17	2.38e-03	14	98	2	SM00200
Domain	ZF_UBP	USP49 USP44	2.38e-03	14	98	2	PS50271
Domain	fn2	FN1 F12	2.38e-03	14	98	2	PF00040
Domain	FN2	FN1 F12	2.38e-03	14	98	2	SM00059
Domain	Sushi	SEZ6L2 VCAN C1S	2.57e-03	52	98	3	PF00084
Domain	CCP	SEZ6L2 VCAN C1S	2.86e-03	54	98	3	SM00032
Domain	Peptidase_S1A	CELA2B F12 PROZ C1S	2.97e-03	113	98	4	IPR001314
Domain	Laminin_N	LAMB4 LAMA1	3.12e-03	16	98	2	IPR008211
Domain	LamNT	LAMB4 LAMA1	3.12e-03	16	98	2	SM00136
Domain	LAMININ_NTER	LAMB4 LAMA1	3.12e-03	16	98	2	PS51117
Domain	Laminin_N	LAMB4 LAMA1	3.12e-03	16	98	2	PF00055
Domain	TRYPSIN_DOM	CELA2B F12 PROZ C1S	3.16e-03	115	98	4	PS50240
Domain	SUSHI	SEZ6L2 VCAN C1S	3.17e-03	56	98	3	PS50923
Domain	ig	HSPG2 ADAMTSL3 CD22 SIGLEC1 CEACAM20	3.27e-03	190	98	5	PF00047
Domain	Immunoglobulin	HSPG2 ADAMTSL3 CD22 SIGLEC1 CEACAM20	3.27e-03	190	98	5	IPR013151
Domain	Sushi_SCR_CCP_dom	SEZ6L2 VCAN C1S	3.34e-03	57	98	3	IPR000436
Domain	Tryp_SPc	CELA2B F12 PROZ C1S	3.36e-03	117	98	4	SM00020
Domain	Trypsin_dom	CELA2B F12 PROZ C1S	3.79e-03	121	98	4	IPR001254
Domain	Trypsin	CELA2B F12 PROZ C1S	3.79e-03	121	98	4	PF00089
Domain	Peptidase_S1_PA	CELA2B F12 PROZ C1S	4.02e-03	123	98	4	IPR009003
Domain	VWC_out	FRAS1 FCGBP	4.40e-03	19	98	2	SM00215
Pathway	REACTOME_ECM_PROTEOGLYCANS	COL3A1 HSPG2 FN1 LAMA1 VCAN	4.80e-05	76	74	5	M27219
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	COL3A1 HSPG2 LAMB4 FN1 LAMA1	7.77e-05	84	74	5	M7098
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	IGSF8 COL3A1 HSPG2 FRAS1 TMEM201 GALNT2 LAMA1 LGR4 POMGNT1 SEZ6L2 IFNGR1 FAT1 METTL9 CLPTM1 LRP1 OSMR CTSZ IGSF3	9.07e-09	1201	100	18	35696571
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	HSPG2 FN1 CUL9 CPT2 SEZ6L2 SPTBN5 CD22 LRP1 OSMR	1.25e-08	214	100	9	22199357
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	COL3A1 HSPG2 FRAS1 FN1 LAMA1 VCAN	3.18e-08	64	100	6	22261194
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	COL3A1 LAMB4 FN1 LAMA1	1.91e-07	18	100	4	11311202
Pubmed	Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.	COL3A1 HSPG2 FN1 LAMA1 VCAN	3.40e-07	50	100	5	23658023
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL3A1 HSPG2 FRAS1 FN1 LAMA1 HMCN2 VCAN	5.71e-07	167	100	7	22159717
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL3A1 HSPG2 FN1 LAMA1 CELA2B HMCN2 CTSZ	7.82e-07	175	100	7	28071719
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	COL3A1 FN1 LAMA1 VCAN	9.16e-07	26	100	4	34189436
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	HSPG2 FRAS1 FN1 LAMA1	1.45e-06	29	100	4	22613833
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ENGASE HSPG2 FRAS1 ABL1 POMGNT1 CUL9 LARS2 TBC1D9 FAT1 KMT2D ZNF276 WDFY3 CTSZ IGSF3	3.43e-06	1105	100	14	35748872
Pubmed	SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix.	COL3A1 HSPG2 FN1	3.74e-06	11	100	3	2745554
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	COL3A1 HSPG2 FN1 GSN HMCN2 VCAN	4.25e-06	146	100	6	27068509
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL3A1 HSPG2 FN1 F12 VCAN CTSZ	5.57e-06	153	100	6	25037231
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	COL3A1 HSPG2 GALNT2 FN1 LAMA1 GSN VCAN	7.84e-06	248	100	7	24006456
Pubmed	Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.	HSPG2 FN1 GSN LRP1	8.00e-06	44	100	4	31273033
Pubmed	Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin-like domains.	CD22 SIGLEC1	8.18e-06	2	100	2	7925291
Pubmed	Human plasma gelsolin binds to fibronectin.	FN1 GSN	8.18e-06	2	100	2	6092370
Pubmed	A heart segmental defect in the anterior-posterior axis of a transgenic mutant mouse.	FN1 VCAN	8.18e-06	2	100	2	9188753
Pubmed	Differential deposition of basement membrane components during formation of the caudal neural tube in the mouse embryo.	HSPG2 FN1	8.18e-06	2	100	2	3665768
Pubmed	Glucose-induced fibronectin and collagen type III expression in renal fibroblasts can occur independent of TGF-beta1.	COL3A1 FN1	8.18e-06	2	100	2	12631068
Pubmed	[Association of single nucleotide polymorphisms of CSPG2 and HSPG2 genes with intracranial aneurysm in ethnic Han Chinese population].	HSPG2 VCAN	8.18e-06	2	100	2	23568740
Pubmed	Versican V2 isoform enhances angiogenesis by regulating endothelial cell activities and fibronectin expression.	FN1 VCAN	8.18e-06	2	100	2	23201264
Pubmed	Siglec-1 and -2 as potential biomarkers in autoimmune disease.	CD22 SIGLEC1	8.18e-06	2	100	2	26752092
Pubmed	The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.	FN1 LRP1	8.18e-06	2	100	2	11867643
Pubmed	Mycobacterium tuberculosis malate synthase is a laminin-binding adhesin.	FN1 LAMA1	8.18e-06	2	100	2	16677310
Pubmed	LRP1 is required for novobiocin-mediated fibronectin turnover.	FN1 LRP1	8.18e-06	2	100	2	30061663
Pubmed	Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression.	FN1 LAMA1	8.18e-06	2	100	2	25885552
Pubmed	The intracranial aneurysm susceptibility genes HSPG2 and CSPG2 are not associated with abdominal aortic aneurysm.	HSPG2 VCAN	8.18e-06	2	100	2	20053631
Pubmed	Membrane-type MMPs are indispensable for placental labyrinth formation and development.	COL3A1 HSPG2 FN1	8.20e-06	14	100	3	20858856
Pubmed	Molecular determinants of epithelial mesenchymal transition in mouse placenta and trophoblast stem cell.	COL3A1 FN1 VCAN	8.20e-06	14	100	3	37414855
Pubmed	Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.	HSPG2 FN1 LAMA1	1.26e-05	16	100	3	17948866
Pubmed	Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.	HSPG2 FRAS1 LAMA1	1.26e-05	16	100	3	16880404
Pubmed	Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.	ACADL RGS12 ELMO1 TBC1D9 GSN CNTNAP2 CNTNAP4 CTSZ	1.36e-05	376	100	8	24154525
Pubmed	A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).	COL3A1 HSPG2 FN1 F12 IFNGR1 VCAN	1.70e-05	186	100	6	20673868
Pubmed	Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.	COL3A1 HSPG2 FN1 F12 IFNGR1 VCAN	1.70e-05	186	100	6	20452482
Pubmed	Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs.	COL3A1 HSPG2 FN1	1.82e-05	18	100	3	12571105
Pubmed	ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.	COL3A1 FN1 LAMA1	1.82e-05	18	100	3	39040056
Pubmed	Topographical variation in the distributions of versican, aggrecan and perlecan in the foetal human spine reflects their diverse functional roles in spinal development.	HSPG2 VCAN	2.45e-05	3	100	2	19669783
Pubmed	The extracellular matrix is a novel attribute of endothelial progenitors and of hypoxic mature endothelial cells.	FN1 LAMA1	2.45e-05	3	100	2	22919069
Pubmed	Heterologously overexpressed, affinity-purified human meprin alpha is functionally active and cleaves components of the basement membrane in vitro.	LAMA1 MEP1A	2.45e-05	3	100	2	10620696
Pubmed	Immunohistochemical localization of syndecan-1 in the dental follicle of postnatal mouse teeth.	HSPG2 FN1	2.45e-05	3	100	2	17608588
Pubmed	Angioinhibitory action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association.	HSPG2 FN1	2.45e-05	3	100	2	19553700
Pubmed	siRNA targeting NBS1 or XIAP increases radiation sensitivity of human cancer cells independent of TP53 status.	XIAP NBN	2.45e-05	3	100	2	16972754
Pubmed	Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily.	CD22 SIGLEC1	2.45e-05	3	100	2	7533044
Pubmed	An old enzyme with a new function: purification and characterization of a distinct matrix-degrading metalloproteinase in rat kidney cortex and its identification as meprin.	FN1 MEP1A	2.45e-05	3	100	2	8063866
Pubmed	Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D.	FAT1 KMT2D	2.45e-05	3	100	2	31123786
Pubmed	Processing of procollagen III by meprins: new players in extracellular matrix assembly?	COL3A1 MEP1A	2.45e-05	3	100	2	20631730
Pubmed	Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.	COL3A1 FN1 MUC17 CTSZ	3.16e-05	62	100	4	28344315
Pubmed	Transforming growth factor-β signaling in myogenic cells regulates vascular morphogenesis, differentiation, and matrix synthesis.	COL3A1 FN1 VCAN	3.41e-05	22	100	3	21979435
Pubmed	Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.	HSPG2 FN1 VCAN	3.92e-05	23	100	3	30814516
Pubmed	Localization of types I and III collagen and fibronectin in the developing mouse palatal shelves.	COL3A1 FN1	4.89e-05	4	100	2	8984825
Pubmed	Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation.	ACACB ACADL	4.89e-05	4	100	2	30043753
Pubmed	Activation of expression of genes coding for extracellular matrix proteins in Tat-producing glioblastoma cells.	COL3A1 FN1	4.89e-05	4	100	2	1409674
Pubmed	[Genetic study for diabetic microvascular complications--recent advances and future perspectives].	ACACB ELMO1	4.89e-05	4	100	2	23156397
Pubmed	Critical Roles of the Histone Methyltransferase MLL4/KMT2D in Murine Hepatic Steatosis Directed by ABL1 and PPARγ2.	ABL1 KMT2D	4.89e-05	4	100	2	27806304
Pubmed	Ultrastructural localization of microfibrillar fibulin-1 and fibulin-2 during heart development indicates a switch in molecular associations.	FN1 VCAN	4.89e-05	4	100	2	9676579
Pubmed	Expression of CD 73 (ecto-5'-nucleotidase) in 165 glioblastomas by immunohistochemistry and electronmicroscopic histochemistry.	FN1 LAMA1	4.89e-05	4	100	2	10470109
Pubmed	Identification of a linkage group including the Bcg gene by restriction fragment length polymorphism analysis.	FN1 CRYBA1	4.89e-05	4	100	2	2901325
Pubmed	The extracellular matrix proteins laminin and fibronectin contain binding domains for human plasminogen and tissue plasminogen activator.	FN1 LAMA1	4.89e-05	4	100	2	8360181
Pubmed	Gelsolin deficiency blocks podosome assembly and produces increased bone mass and strength.	GSN PIK3C2A	4.89e-05	4	100	2	10684249
Pubmed	Association analysis of genes involved in the maintenance of the integrity of the extracellular matrix with intracranial aneurysms in a Japanese cohort.	HSPG2 VCAN	4.89e-05	4	100	2	19506372
Pubmed	Tissue transglutaminase mediates the pro-malignant effects of oncostatin M receptor over-expression in cervical squamous cell carcinoma.	FN1 OSMR	4.89e-05	4	100	2	23765377
Pubmed	Colocalization of TGF-beta 1 and collagen I and III, fibronectin and glycosaminoglycans during lung branching morphogenesis.	COL3A1 FN1	4.89e-05	4	100	2	2209468
Pubmed	Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis.	HSPG2 FN1 LAMA1	5.07e-05	25	100	3	19373938
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	PCSK2 PLA2G3 CUL9 RGS12 SPTBN5	5.83e-05	142	100	5	19851296
Pubmed	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	PCSK2 PLA2G3 CUL9 RGS12 SPTBN5	6.03e-05	143	100	5	20198315
Pubmed	The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes.	FN1 LAMA1	8.14e-05	5	100	2	28092265
Pubmed	Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis.	COL3A1 FN1	8.14e-05	5	100	2	10995453
Pubmed	Immunohistochemical localization of Pax2 and associated proteins in the developing kidney of mice with renal hypoplasia.	FN1 LAMA1	8.14e-05	5	100	2	11511678
Pubmed	The N-terminal globular domain of the laminin alpha1 chain binds to alpha1beta1 and alpha2beta1 integrins and to the heparan sulfate-containing domains of perlecan.	HSPG2 LAMA1	8.14e-05	5	100	2	9688542
Pubmed	Caspr3 and caspr4, two novel members of the caspr family are expressed in the nervous system and interact with PDZ domains.	CNTNAP2 CNTNAP4	8.14e-05	5	100	2	12093160
Pubmed	Spatial and temporal changes in chondroitin sulfate distribution in the sclerotome play an essential role in the formation of migration patterns of mouse neural crest cells.	HSPG2 FN1	8.14e-05	5	100	2	9915576
Pubmed	Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake.	HSPG2 LRP1	8.14e-05	5	100	2	21289173
Pubmed	Disruption of the talin gene arrests mouse development at the gastrulation stage.	HSPG2 FN1	8.14e-05	5	100	2	11084655
Pubmed	Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan.	HSPG2 FN1	8.14e-05	5	100	2	11493006
Pubmed	Extracellular matrix protein expression during mouse detrusor development.	COL3A1 FN1	8.14e-05	5	100	2	12592609
Pubmed	COL3A1, CXCL8, VCAN, THBS2, and COL1A2 are correlated with the onset of biliary atresia.	COL3A1 VCAN	8.14e-05	5	100	2	36930067
Pubmed	Interactions of the amino-terminal noncollagenous (NC1) domain of type VII collagen with extracellular matrix components. A potential role in epidermal-dermal adherence in human skin.	FN1 LAMA1	8.14e-05	5	100	2	9169408
Pubmed	Expression of Nephronectin in the Descemet's membrane of mouse corneas during development and adult homeostasis.	HSPG2 LAMA1	8.14e-05	5	100	2	38246333
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	DGKZ BTBD9 GSN CYFIP1 LRP1 SEPTIN7	9.00e-05	251	100	6	27507650
Pubmed	Functional analysis of secreted and transmembrane proteins critical to mouse development.	FN1 LAMA1 FAT1	9.78e-05	31	100	3	11431694
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	HSPG2 FN1 F12 FCGBP LRP1 C1S	1.02e-04	257	100	6	16335952
Pubmed	Characterization of molecules binding to the 70K N-terminal region of fibronectin by IFAST purification coupled with mass spectrometry.	FN1 GSN C1S	1.08e-04	32	100	3	23750785
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	COL3A1 HSPG2 FN1 VCAN	1.14e-04	86	100	4	28327460
Pubmed	MLL4 is required after implantation, whereas MLL3 becomes essential during late gestation.	FN1 LAMA1 KMT2D	1.18e-04	33	100	3	32439762
Pubmed	Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly.	PCSK2 CNTRL	1.22e-04	6	100	2	15337773
Pubmed	Absence of post-phosphoryl modification in dystroglycanopathy mouse models and wild-type tissues expressing non-laminin binding form of α-dystroglycan.	LAMA1 POMGNT1	1.22e-04	6	100	2	22270369
Pubmed	Differential expression of glycosaminoglycans and proteoglycans in the migratory pathway of the primordial germ cells of the mouse.	HSPG2 VCAN	1.22e-04	6	100	2	12122449
Pubmed	The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.	HSPG2 FN1	1.22e-04	6	100	2	11956183
Pubmed	Over-expression of the chondroitin sulphate proteoglycan versican is associated with defective neural crest migration in the Pax3 mutant mouse (splotch).	HSPG2 VCAN	1.22e-04	6	100	2	9486530
Pubmed	Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.	HSPG2 LAMA1	1.22e-04	6	100	2	15668394
Pubmed	The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells.	CUL9 XIAP	1.22e-04	6	100	2	25028717
Pubmed	Influenza Vaccination Induces NK-Cell-Mediated Type-II IFN Response that Regulates Humoral Immunity in an IL-6-Dependent Manner.	IFNGR1 SIGLEC1	1.22e-04	6	100	2	30811982
Pubmed	Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.	FN1 LAMA1	1.22e-04	6	100	2	28348210
Pubmed	STING-Licensed Macrophages Prime Type I IFN Production by Plasmacytoid Dendritic Cells in the Bone Marrow during Severe Plasmodium yoelii Malaria.	IFNGR1 SIGLEC1	1.22e-04	6	100	2	27792766
Pubmed	Promotion of tumor cell migration by extracellular matrix proteins in human pancreatic cancer.	COL3A1 FN1	1.22e-04	6	100	2	19893454
Pubmed	Biochemical dissection of Anosmin-1 interaction with FGFR1 and components of the extracellular matrix.	FN1 LAMA1	1.22e-04	6	100	2	20874775
Pubmed	Galnt1 is required for normal heart valve development and cardiac function.	GALNT2 FN1 VCAN	1.54e-04	36	100	3	25615642
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	DGKZ BTBD9 GSN CYFIP1 PPP1R9B SEPTIN7	1.66e-04	281	100	6	28706196
Pubmed	Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.	COL3A1 FN1 LAMA1	1.67e-04	37	100	3	34323105
Interaction	PRELP interactions	HSPG2 FRAS1 FN1 CUL9 SEZ6L2	4.45e-07	32	98	5	int:PRELP
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 ADAMTSL3 HMCN2 SIGLEC1 CEACAM20	4.27e-04	161	71	5	593
GeneFamily	Adenosine receptors\|V-set domain containing	IGSF8 BTN3A3 VCAN SIGLEC1 IGSF3	4.51e-04	163	71	5	590
GeneFamily	Immunoglobulin like domain containing	HSPG2 ADAMTSL3 HMCN2 CEACAM20 IGSF3	9.69e-04	193	71	5	594
GeneFamily	Laminin subunits	LAMB4 LAMA1	9.78e-04	12	71	2	626
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SEZ6L2 VCAN C1S	1.46e-03	57	71	3	1179
Coexpression	RUBENSTEIN_SKELETAL_MUSCLE_FAP_CELLS	COL3A1 HSPG2 FN1 GSN VCAN LRP1 C1S FHL1	4.08e-07	179	99	8	M41745
Coexpression	JOHNSTONE_PARVB_TARGETS_3_UP	FRAS1 FN1 LGR4 POMGNT1 SEZ6L2 TBC1D9 GSN BTN3A3 LRP1 C1S OSMR	7.54e-07	433	99	11	M2240
Coexpression	HALLMARK_COAGULATION	FN1 F12 GSN MEP1A PROZ LRP1 C1S	9.57e-07	138	99	7	M5946
Coexpression	NABA_MATRISOME	COL3A1 HSPG2 LAMB4 FRAS1 FN1 LAMA1 HPSE2 CELA2B ADAMTSL3 F12 MEP1A KY HMCN2 MUC17 VCAN CTSZ	1.45e-06	1026	99	16	M5889
Coexpression	VERRECCHIA_EARLY_RESPONSE_TO_TGFB1	COL3A1 HSPG2 FN1 VCAN LRP1	1.90e-06	54	99	5	M4737
Coexpression	NABA_MATRISOME	COL3A1 HSPG2 FRAS1 FN1 LAMA1 HPSE2 CELA2B ADAMTSL3 F12 MEP1A KY HMCN2 MUC17 VCAN CTSZ	5.64e-06	1008	99	15	MM17056
Coexpression	WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP	COL3A1 FN1 MEP1A IFNGR1 BTN3A3 C1S	6.74e-06	121	99	6	M8475
Coexpression	NABA_MATRISOME_PRIMARY_METASTATIC_LUNG_TUMOR	COL3A1 HSPG2 FN1 LAMA1	9.16e-06	35	99	4	MM17054
Coexpression	NABA_CORE_MATRISOME	COL3A1 HSPG2 LAMB4 FRAS1 FN1 LAMA1 HMCN2 VCAN	9.95e-06	275	99	8	M5884
Coexpression	GSE27786_LIN_NEG_VS_MONO_MAC_DN	PLA2G3 ADAMTSL3 KMT2D CYFIP1 SEPTIN7 CHAC1 ATG16L2	1.12e-05	200	99	7	M4798
Coexpression	PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP	COL3A1 HSPG2 FN1 CYFIP1 C1S WDFY3 OSMR	1.58e-05	211	99	7	M12225
Coexpression	IGLESIAS_E2F_TARGETS_UP	COL3A1 ACADL GSN CYFIP1 SEPTIN7 CTSZ	1.82e-05	144	99	6	M1484
Coexpression	IGLESIAS_E2F_TARGETS_UP	COL3A1 ACADL GSN CYFIP1 SEPTIN7 CTSZ	2.13e-05	148	99	6	MM1010
Coexpression	NABA_ECM_REGULATORS	HPSE2 CELA2B ADAMTSL3 F12 MEP1A KY CTSZ	3.41e-05	238	99	7	M3468
Coexpression	NABA_ECM_REGULATORS	HPSE2 CELA2B ADAMTSL3 F12 MEP1A KY CTSZ	3.79e-05	242	99	7	MM17062
Coexpression	MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP	HSPG2 GALNT2 FN1 GSN VCAN FHL1	4.34e-05	168	99	6	M1124
Coexpression	FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	COL3A1 NBN GSN IFNGR1 FAT1 PIK3C2A VCAN C1S WDFY3 FHL1	5.84e-05	568	99	10	M4023
Coexpression	VERRECCHIA_RESPONSE_TO_TGFB1_C2	COL3A1 FN1 LRP1	6.62e-05	21	99	3	M4767
Coexpression	MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP	HSPG2 GALNT2 FN1 GSN VCAN FHL1	6.77e-05	182	99	6	MM993
Coexpression	NABA_CORE_MATRISOME	COL3A1 HSPG2 FRAS1 FN1 LAMA1 HMCN2 VCAN	7.56e-05	270	99	7	MM17057
Coexpression	POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN	COL3A1 CYFIP1 VCAN C1S	8.47e-05	61	99	4	M8510
Coexpression	HEBERT_MATRISOME_TNBC_LUNG_METASTASIS	COL3A1 HSPG2 LAMA1	8.76e-05	23	99	3	M48001
Coexpression	MOOTHA_FFA_OXYDATION	ACADL NBN CPT2	9.99e-05	24	99	3	M15531
Coexpression	GSE42021_TREG_VS_TCONV_PLN_UP	NBN LARS2 ADAMTSL3 BTN3A3 C1S OSMR	1.14e-04	200	99	6	M9572
Coexpression	RUBENSTEIN_SKELETAL_MUSCLE_FBN1_FAP_CELLS	COL3A1 FN1 GSN VCAN LRP1 C1S FHL1	1.15e-04	289	99	7	M41750
Coexpression	DESCARTES_FETAL_THYMUS_STROMAL_CELLS	COL3A1 ADAMTSL3 VCAN LRP1 C1S	1.75e-04	137	99	5	M40313
Coexpression	NABA_MATRISOME_METASTATIC_LUNG_LYMPH_NODE_METASTASIS	COL3A1 FN1 LAMA1	1.78e-04	29	99	3	MM17055
Coexpression	TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_DN	COL3A1 FN1 BTN3A3 VCAN	1.80e-04	74	99	4	M13547
Coexpression	HEBERT_MATRISOME_TNBC_LUNG_METASTASIS_TUMOR_CELL_DERIVED	COL3A1 LAMA1	2.10e-04	6	99	2	M48000
Coexpression	RODWELL_AGING_KIDNEY_NO_BLOOD_UP	COL3A1 FN1 CYFIP1 C1S OSMR FHL1	2.11e-04	224	99	6	M9893
Coexpression	WEST_ADRENOCORTICAL_TUMOR_DN	PCSK2 AMT MID2 ADAMTSL3 METTL9 VCAN LRP1 C1S FHL1	2.27e-04	546	99	9	M3837
Coexpression	MENON_FETAL_KIDNEY_3_STROMAL_CELLS	COL3A1 FN1 VCAN SEPTIN7	2.55e-04	81	99	4	M39253
Coexpression	GSE7509_FCGRIIB_VS_TNFA_IL1B_IL6_PGE_STIM_DC_DN	STAB2 ARID4A CNTRL DGKZ ZNF276	3.01e-04	154	99	5	M6824
Coexpression	GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_UP	ACADL CPT2 USP44 CLPTM1 LSM4	3.10e-04	155	99	5	M358
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500	COL3A1 FN1 LAMA1 HPSE2 VCAN LRP1	3.11e-05	130	98	6	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	COL3A1 HSPG2 FN1 ADAMTSL3 GSN FAT1 VCAN LRP1 OSMR FHL1	4.00e-05	445	98	10	GSM777043_500
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000	PCSK2 FN1 MID2 LAMA1 HPSE2 ADARB1 GSN MEP1A VCAN C1S WDFY3 OSMR FHL1 SHISA3	6.89e-05	905	98	14	gudmap_kidney_P0_JuxtaGlom_Ren1_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_k-means-cluster#3_top-relative-expression-ranked_100	GSN EHF OSMR	8.75e-05	19	98	3	gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_100_k3
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL3A1 FN1 HPSE2 ELMO1 VCAN CNTNAP2 LRP1 FHL1 SHISA3	5.30e-10	194	99	9	8c37bedb23285735ff3828db3889897fada8c95d
ToppCell	Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	COL3A1 HSPG2 FN1 GSN VCAN LRP1 C1S OSMR FHL1	6.63e-10	199	99	9	40de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL3A1 FN1 LAMA1 ADARB1 VCAN LRP1 C1S OSMR FHL1	6.63e-10	199	99	9	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 FN1 ADAMTSL3 GSN VCAN LRP1 C1S FHL1 SHISA3	6.93e-10	200	99	9	6f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 FN1 ADAMTSL3 GSN VCAN LRP1 C1S FHL1 SHISA3	6.93e-10	200	99	9	3a164e3971bcd62b148b813171c103adb81f972e
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL3A1 FN1 ADARB1 GSN IFNGR1 LRP1 C1S FHL1	7.36e-09	181	99	8	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL3A1 FN1 ADARB1 GSN IFNGR1 LRP1 C1S FHL1	8.37e-09	184	99	8	924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL3A1 PCSK2 FN1 HPSE2 ELMO1 VCAN CNTNAP2 SHISA3	1.08e-08	190	99	8	7986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL3A1 FN1 ADARB1 GSN VCAN LRP1 FHL1 SHISA3	1.12e-08	191	99	8	a05e9a7eb137d804570dd7d8905975d735738767
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FN1 ADAMTSL3 GSN LRP1 C1S OSMR SHISA3	1.17e-08	192	99	8	853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCell	PND14-Mesenchymal-Mesenchymal_structural\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FN1 ADARB1 GSN VCAN LRP1 C1S FHL1	1.17e-08	192	99	8	25492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FN1 ADAMTSL3 GSN LRP1 C1S OSMR SHISA3	1.17e-08	192	99	8	d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FN1 ADARB1 GSN VCAN LRP1 C1S FHL1	1.17e-08	192	99	8	de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 HSPG2 GSN VCAN LRP1 C1S IGSF3 SHISA3	1.17e-08	192	99	8	011634a24b0c61d9b463fe755502edbc5cd70b7a
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FN1 ADAMTSL3 GSN LRP1 C1S OSMR SHISA3	1.17e-08	192	99	8	49281626ecad0456fdbded2378b7028d7b589686
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF8 COL3A1 HSPG2 FN1 GSN VCAN LRP1 C1S	1.17e-08	192	99	8	2d9e2262f1342fe17735f21f733c029d1275e955
ToppCell	ILEUM-inflamed-(8)_Smooth_muscle_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	COL3A1 LAMB4 FN1 HPSE2 ADAMTSL3 FAT1 C1S FHL1	1.22e-08	193	99	8	084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 GSN LRP1 C1S FHL1 IGSF3	1.22e-08	193	99	8	eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FN1 ADAMTSL3 GSN VCAN LRP1 C1S FHL1	1.22e-08	193	99	8	160691b671710be10220803d788c2c961c236af1
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF8 COL3A1 HSPG2 FN1 GSN VCAN LRP1 C1S	1.22e-08	193	99	8	45b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	COL3A1 FN1 LGR4 GSN HMCN2 VCAN LRP1 C1S	1.27e-08	194	99	8	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	COL3A1 FN1 LGR4 ADAMTSL3 GSN VCAN LRP1 C1S	1.32e-08	195	99	8	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 FN1 HPSE2 VCAN LRP1 C1S FHL1 SHISA3	1.54e-08	199	99	8	84545ced0c792bc77980a50d65e484eab648d47e
ToppCell	ILEUM-non-inflamed-(8)_Fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	COL3A1 FN1 ARID4A HPSE2 VCAN LRP1 C1S FHL1	1.54e-08	199	99	8	d9d7f36b4b5592b7855448730044c90997b55499
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL3A1 FN1 ADAMTSL3 GSN KY VCAN LRP1 FHL1	1.54e-08	199	99	8	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL3A1 FN1 LAMA1 VCAN LRP1 C1S OSMR FHL1	1.60e-08	200	99	8	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 FN1 HPSE2 VCAN LRP1 C1S FHL1 SHISA3	1.60e-08	200	99	8	3dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL3A1 FN1 ADAMTSL3 ADARB1 ELMO1 VCAN LRP1 FHL1	1.60e-08	200	99	8	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL3A1 FN1 ADAMTSL3 ADARB1 ELMO1 VCAN LRP1 FHL1	1.60e-08	200	99	8	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL3A1 FRAS1 FN1 ADAMTSL3 ADARB1 ELMO1 LRP1 FHL1	1.60e-08	200	99	8	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 FN1 HPSE2 VCAN LRP1 C1S FHL1 SHISA3	1.60e-08	200	99	8	ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FN1 ADARB1 GSN CNTNAP2 LRP1 C1S FHL1	8.10e-08	163	99	7	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	COL3A1 FN1 ADARB1 ELMO1 GSN LRP1 FHL1	8.45e-08	164	99	7	519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL3A1 FN1 ADARB1 GSN IFNGR1 LRP1 FHL1	1.27e-07	174	99	7	3c47d069bd836599a8d40eae485c23d4d3487517
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 FN1 GSN VCAN C1S FHL1 SHISA3	1.65e-07	181	99	7	e1ae9ada60ec89e7a7cde9c231c1a099ed2ffecc
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	COL3A1 FN1 ADARB1 ELMO1 GSN LRP1 FHL1	1.72e-07	182	99	7	ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 FN1 ADAMTSL3 GSN VCAN LRP1 C1S	1.72e-07	182	99	7	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FN1 LGR4 ADAMTSL3 GSN HMCN2 VCAN LRP1	1.92e-07	185	99	7	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL3A1 FN1 ADARB1 GSN IFNGR1 LRP1 FHL1	1.92e-07	185	99	7	46460e74cc613df9043f5404e7342aa13cc34873
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABL1 FN1 VCAN LRP1 C1S OSMR FHL1	1.99e-07	186	99	7	f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL3A1 FN1 ADARB1 GSN IFNGR1 LRP1 FHL1	1.99e-07	186	99	7	88e6246172d816806a498a5c1f38e699f2f5d7c2
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic\|GI_large-bowel / Manually curated celltypes from each tissue	FN1 FCGBP VCAN LRP1 SIGLEC1 WDFY3 CTSZ	2.14e-07	188	99	7	d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_large-bowel / Manually curated celltypes from each tissue	FN1 FCGBP VCAN LRP1 SIGLEC1 WDFY3 CTSZ	2.14e-07	188	99	7	0bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 GSN LRP1 FHL1 IGSF3	2.14e-07	188	99	7	7191087d8754f5e8700e3d744cd920ee26db1e57
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	COL3A1 FN1 GSN HMCN2 VCAN LRP1 FHL1	2.14e-07	188	99	7	409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 GSN LRP1 C1S FHL1	2.22e-07	189	99	7	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 FN1 HPSE2 ADARB1 ELMO1 CNTNAP2 FHL1	2.22e-07	189	99	7	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	HSPG2 FN1 ELMO1 KIAA1671 PIK3C2A VCAN OSMR	2.22e-07	189	99	7	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FN1 ADARB1 GSN LRP1 C1S FHL1	2.22e-07	189	99	7	324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 LAMA1 LGR4 ADAMTSL3 RGS12 FCGBP UGT2B7	2.30e-07	190	99	7	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 GSN VCAN LRP1 C1S	2.30e-07	190	99	7	bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 GSN VCAN LRP1 C1S	2.30e-07	190	99	7	e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 GSN VCAN LRP1 C1S	2.30e-07	190	99	7	ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 LAMA1 LGR4 ADAMTSL3 RGS12 FCGBP UGT2B7	2.30e-07	190	99	7	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 ADARB1 VCAN LRP1 C1S OSMR FHL1	2.30e-07	190	99	7	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 GSN LRP1 C1S FHL1	2.30e-07	190	99	7	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	COL3A1 FN1 HPSE2 ADAMTSL3 ADARB1 VCAN FHL1	2.30e-07	190	99	7	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 GSN LRP1 C1S FHL1	2.30e-07	190	99	7	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 GSN LRP1 C1S FHL1	2.30e-07	190	99	7	47077579496c5340e99f61499427a3a36b566da3
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 ADARB1 VCAN LRP1 C1S OSMR FHL1	2.38e-07	191	99	7	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 HSPG2 GSN LRP1 C1S IGSF3 SHISA3	2.38e-07	191	99	7	2b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FRAS1 FN1 GSN VCAN LRP1 C1S	2.38e-07	191	99	7	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 FN1 ADARB1 GSN LRP1 C1S FHL1	2.38e-07	191	99	7	094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 GSN LRP1 C1S FHL1	2.38e-07	191	99	7	a57cf0519d749febc0b69fe0b098b7ba53d63258
ToppCell	(2)_Fibroblasts-(21)_Fibro-2\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	IGSF8 COL3A1 PCSK2 FN1 GSN LRP1 FHL1	2.38e-07	191	99	7	5ee353c79055c08e8a3e2b43a0345bceb09f3890
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 FN1 ADARB1 GSN LRP1 C1S FHL1	2.38e-07	191	99	7	80484d39f34703a33b9bac09826b7a526e883cab
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 GSN LRP1 C1S FHL1	2.38e-07	191	99	7	19c67a812b8ce97472d316acd15aeefe8736000d
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 FN1 ADARB1 GSN LRP1 C1S FHL1	2.38e-07	191	99	7	5c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 ADAMTSL3 GSN VCAN LRP1 C1S FHL1	2.47e-07	192	99	7	5e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 HSPG2 GSN HMCN2 LRP1 C1S IGSF3	2.47e-07	192	99	7	29bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 HSPG2 GSN HMCN2 LRP1 C1S IGSF3	2.47e-07	192	99	7	cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 FN1 LARS2 GSN FAT1 VCAN C1S	2.47e-07	192	99	7	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 ADAMTSL3 GSN VCAN LRP1 C1S FHL1	2.47e-07	192	99	7	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL3A1 FN1 HPSE2 ELMO1 CNTNAP2 FHL1 SHISA3	2.56e-07	193	99	7	9f69edc97b868d23998abc98928a2e89a885ef8a
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF8 COL3A1 HSPG2 GSN VCAN LRP1 C1S	2.56e-07	193	99	7	49600db68ed65cafc67bd45a285b364e4f5f88af
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FN1 ADARB1 GSN LRP1 C1S FHL1	2.56e-07	193	99	7	4c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FN1 ADARB1 GSN LRP1 C1S FHL1	2.56e-07	193	99	7	ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FN1 ADARB1 GSN VCAN FHL1 SHISA3	2.56e-07	193	99	7	8d05805295c5d3aa93aeb38be5fbefa81e1be1f0
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FN1 ADARB1 GSN VCAN FHL1 SHISA3	2.56e-07	193	99	7	1b2cc627b2aa002b442358bd1188d470e67ce7d9
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 HSPG2 GSN LRP1 C1S IGSF3 SHISA3	2.56e-07	193	99	7	e27885a9e1a2a3e165c5366d4cfcda05c5454483
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 ADAMTSL3 GSN VCAN LRP1 C1S FHL1	2.56e-07	193	99	7	25248b8e65d558b1a96a87c93e3e5b4c0ba168fe
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 ADAMTSL3 GSN VCAN LRP1 C1S FHL1	2.56e-07	193	99	7	f1f1097204e07a7bed416425b8256942038a734f
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	COL3A1 FN1 LGR4 ADAMTSL3 GSN VCAN C1S	2.65e-07	194	99	7	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 ADAMTSL3 GSN VCAN STK33 LRP1 C1S	2.65e-07	194	99	7	bbc625b4cc53bb7d6254fde287258e51f9171572
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FN1 HPSE2 ADARB1 ELMO1 VCAN CNTNAP2 FHL1	2.65e-07	194	99	7	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	facs-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 ADAMTSL3 GSN VCAN STK33 LRP1 C1S	2.65e-07	194	99	7	fcd5e9238d299c41f0bf9693b56cd8c900d2112b
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	COL3A1 FN1 LGR4 ADAMTSL3 GSN VCAN C1S	2.65e-07	194	99	7	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	HSPG2 FN1 ELMO1 GSN KIAA1671 PIK3C2A OSMR	2.65e-07	194	99	7	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 VCAN LRP1 C1S FHL1	2.65e-07	194	99	7	ee6b5fb4e993a4c0dc556091b8fefd56bdc70d8f
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL3A1 FN1 HPSE2 ELMO1 CNTNAP2 FHL1 SHISA3	2.65e-07	194	99	7	71d3c7448b1734de54187f902f65649f9283bd4c
ToppCell	Mesenchymal_cells-Arteriolar_fibro.\|World / Lineage and Cell class	COL3A1 HSPG2 FN1 GSN HMCN2 LRP1 FHL1	2.65e-07	194	99	7	c1e8923a50b4138a1e4c054c0c17b7f7122aa8a9
ToppCell	RA\|World / Chamber and Cluster_Paper	FRAS1 FN1 LGR4 ADAMTSL3 GSN FAT1 VCAN	2.65e-07	194	99	7	08f0afbb68a63150fbe107a5337299081c3f69e4
ToppCell	facs-Heart-RA-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 ADAMTSL3 GSN VCAN LRP1 C1S IGSF3	2.65e-07	194	99	7	bc945450b350f597c3ff910d3a14a533d90086a8
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 ADAMTSL3 GSN VCAN STK33 LRP1 C1S	2.65e-07	194	99	7	6afc21c5fec30ab8e373e3e46ab7866204c805b6
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HSPG2 FN1 VCAN LRP1 C1S FHL1	2.74e-07	195	99	7	841fde528ecb293e07b5e00e499d1e9f0b0dce14
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FN1 ADARB1 GSN VCAN C1S FHL1	2.74e-07	195	99	7	cbe518b465b4ef32797ae6b608219207c08493df
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FN1 ADARB1 GSN VCAN FHL1 SHISA3	2.74e-07	195	99	7	b616ee6f1d878935d293c8e0a8bbc5b4385301f0
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 ADAMTSL3 GSN VCAN LRP1 C1S IGSF3	2.74e-07	195	99	7	690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCell	PND03-Mesenchymal-Mesenchymal_structural\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 FN1 ADARB1 GSN VCAN C1S FHL1	2.74e-07	195	99	7	136b06b0931a69b1241101f68c01c44c70365fd9
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	COL3A1 FN1 LGR4 GSN HMCN2 VCAN LRP1	2.74e-07	195	99	7	a78b605b49acd8c9d68716266ca269dafcd910b9
Computational	Serine proteases.	CELA2B F12 PROZ C1S	7.10e-05	39	62	4	MODULE_109
Drug	Verteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A	GALNT2 FN1 LGR4 IFNGR1 FAT1 ZNF276 CLPTM1 IGSF3	3.61e-07	155	98	8	6817_DN
Drug	Liothyronine [6893-02-3]; Up 200; 6.2uM; MCF7; HT_HG-U133A	FRAS1 STAB2 FN1 CUL9 RGS12 SPTBN5 L3MBTL1 CD22	2.29e-06	198	98	8	3324_UP
Drug	Methylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; MCF7; HT_HG-U133A	FN1 CUL9 RGS12 ELMO1 GSN SPTBN5 CNTNAP2 WDFY3	2.38e-06	199	98	8	3333_UP
Drug	Paclitaxel	COL3A1 FRAS1 FN1 ACADL XIAP GSN PIK3C2A VCAN EHF FSHR C1S OSMR FHL1	1.29e-05	720	98	13	ctd:D017239
Drug	rottlerin; Up 200; 10uM; MCF7; HT_HG-U133A_EA	ITFG2 CUL9 RGS12 BTN3A3 L3MBTL1 CTSZ CHAC1	1.84e-05	190	98	7	914_UP
Drug	Amitryptiline hydrochloride [549-18-8]; Up 200; 12.8uM; PC3; HT_HG-U133A	AMT STAB2 ADARB1 RGS12 VCAN CNTNAP2 OSMR	1.97e-05	192	98	7	6353_UP
Drug	Clozapine [5786-21-0]; Up 200; 12.2uM; PC3; HT_HG-U133A	FN1 PLA2G3 ZNF343 TASL ADARB1 RGS12 L3MBTL1	2.04e-05	193	98	7	4670_UP
Drug	Kaempferol [520-18-3]; Down 200; 14uM; PC3; HT_HG-U133A	MID2 ITFG2 CPT2 CD22 EHF FHL1 CTSZ	2.04e-05	193	98	7	5839_DN
Drug	poly(3-hydroxybutyrate-co-3-hydroxyvalerate	HSPG2 FN1 C1S	2.14e-05	13	98	3	CID000107801
Drug	wortmannin from Penicillium funiculosum; Up 200; 0.01uM; PC3; HT_HG-U133A	COL3A1 ITFG2 ARID4A ZNF343 SPTBN5 LRP1 SIGLEC1	2.17e-05	195	98	7	4467_UP
Drug	Napelline [5008-52-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A	COL3A1 LAMB4 GSN SPTBN5 CD22 VCAN FHL1	2.25e-05	196	98	7	6084_UP
Drug	Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	FRAS1 FN1 ADAMTSL3 TASL RGS12 BTN3A3 FHL1	2.32e-05	197	98	7	3577_UP
Drug	Sotalol hydrochloride [959-24-0]; Down 200; 13uM; PC3; HT_HG-U133A	HSPG2 ITFG2 CPT2 LARS2 ADARB1 TBC1D9 L3MBTL1	2.32e-05	197	98	7	4079_DN
Drug	Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; PC3; HT_HG-U133A	COL3A1 HSPG2 PLA2G3 SPTBN5 L3MBTL1 VCAN SEPTIN7	2.32e-05	197	98	7	4618_UP
Drug	Vitexin [3681-93-4]; Up 200; 9.2uM; MCF7; HT_HG-U133A	LAMB4 FN1 ACACB CNTRL GSN CNTNAP2 WDFY3	2.32e-05	197	98	7	2810_UP
Drug	Ronidazole [7681-76-7]; Up 200; 20uM; MCF7; HT_HG-U133A	STAB2 FN1 RGS12 L3MBTL1 CD22 CNTNAP2 FHL1	2.40e-05	198	98	7	3557_UP
Drug	Chlorhexidine [55-56-1]; Up 200; 8uM; PC3; HT_HG-U133A	TASL RGS12 ZNF276 L3MBTL1 VCAN EHF CTSZ	2.40e-05	198	98	7	6302_UP
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A	LAMB4 AMT FN1 ITFG2 CNTNAP2 SIGLEC1 CTSZ	2.56e-05	200	98	7	5570_UP
Drug	LMWH	COL3A1 HSPG2 LAMB4 FN1 LAMA1 F12 PROZ PIK3C2A VCAN LRP1 C1S LRP2BP	2.78e-05	663	98	12	CID000000772
Drug	ezetimibe	PCSK2 NBN PIK3C2A LRP1 UGT2B7 LRP2BP	4.22e-05	147	98	6	CID000150311
Drug	methdilazine	NBN PROZ	5.49e-05	3	98	2	CID000014676
Drug	Bezafibrate	FN1 ACACB ACADL BTBD9 CPT2 VCAN UGT2B7	6.05e-05	229	98	7	ctd:D001629
Drug	Verteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A	FN1 LGR4 SEZ6L2 FAT1 CLPTM1 IGSF3	7.01e-05	161	98	6	3556_DN
Drug	kalinin	HSPG2 LAMB4 FN1 LAMA1	9.30e-05	55	98	4	CID000032518
Drug	palladium nitrate	VCAN SIGLEC1	1.09e-04	4	98	2	CID000024932
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	ACACB ITFG2 ADARB1 SPTBN5 L3MBTL1 ANKRA2	1.42e-04	183	98	6	5599_UP
Drug	retinoic acid; Down 200; 1uM; HL60; HT_HG-U133A	GALNT2 ITFG2 L3MBTL1 VCAN FHL1 CHAC1	1.59e-04	187	98	6	2671_DN
Drug	Rescinnamin [24815-24-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A	ACACB PLA2G3 ELMO1 L3MBTL1 VCAN CHAC1	1.64e-04	188	98	6	4386_UP
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	AMT STAB2 ITFG2 ADARB1 VCAN CNTNAP2	1.64e-04	188	98	6	5596_UP
Drug	LY 294002; Down 200; 10uM; HL60; HT_HG-U133A	FN1 ITFG2 VCAN WDFY3 FHL1 CHAC1	1.64e-04	188	98	6	6186_DN
Drug	Hymecromone	FN1 VCAN UGT2B7	1.66e-04	25	98	3	ctd:D006923
Drug	ghavamiol	VCAN C1S SIGLEC1	1.66e-04	25	98	3	CID005288390
Drug	Piperine [94-62-2]; Down 200; 14uM; PC3; HT_HG-U133A	ITFG2 TASL L3MBTL1 VCAN CNTNAP2 CHAC1	1.79e-04	191	98	6	4247_DN
Drug	Digitoxigenin [143-62-4]; Down 200; 10.6uM; PC3; HT_HG-U133A	HSPG2 NBN ANKRA2 WDFY3 OSMR IGSF3	1.79e-04	191	98	6	4217_DN
Drug	AC1NOOVE	CD22 SIGLEC1	1.82e-04	5	98	2	CID005116706
Drug	3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A	TASL ADARB1 BTN3A3 CD22 VCAN SEPTIN7	1.84e-04	192	98	6	5624_UP
Drug	Pipenzolate bromide [125-51-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A	ITFG2 CUL9 ADARB1 GSN VCAN FHL1	1.84e-04	192	98	6	3460_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	AMT PLA2G3 ADARB1 CNTNAP2 WDFY3 FHL1	1.84e-04	192	98	6	3332_UP
Drug	rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	AMT ITFG2 CNTRL CUL9 RGS12 ANKRA2	1.89e-04	193	98	6	921_UP
Drug	Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; PC3; HT_HG-U133A	HSPG2 ACACB MID2 VCAN OSMR IGSF3	1.95e-04	194	98	6	4219_DN
Drug	Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; PC3; HT_HG-U133A	COL3A1 FN1 ADARB1 KMT2D VCAN C1S	1.95e-04	194	98	6	6696_UP
Drug	Guanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; PC3; HT_HG-U133A	PCSK2 HSPG2 FN1 ZNF343 L3MBTL1 CLPTM1	1.95e-04	194	98	6	4660_UP
Drug	Hydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; PC3; HT_HG-U133A	AMT ITFG2 TBC1D9 VCAN LRP1 SEPTIN7	1.95e-04	194	98	6	6660_DN
Drug	Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A	COL3A1 FRAS1 ACACB CUL9 RGS12 CHAC1	1.95e-04	194	98	6	3285_UP
Drug	Metaraminol bitartrate [33402-03-8]; Down 200; 8.6uM; PC3; HT_HG-U133A	STAB2 L3MBTL1 CD22 VCAN CNTNAP2 SEPTIN7	2.00e-04	195	98	6	3669_DN
Drug	Ethotoin [86-35-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A	COL3A1 LAMB4 FN1 RGS12 LRP1 FHL1	2.00e-04	195	98	6	6052_UP
Drug	Gentamicine sulfate [1405-41-0]; Down 200; 2.6uM; MCF7; HT_HG-U133A	ENGASE ARID4A CNTRL CUL9 RGS12 FHL1	2.00e-04	195	98	6	2245_DN
Drug	carbamazepine; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	AMT STAB2 ACACB ITFG2 RGS12 L3MBTL1	2.00e-04	195	98	6	919_UP
Drug	Xamoterol hemifumarate [73210-73-8]; Up 200; 5uM; MCF7; HT_HG-U133A	ZNF343 ADAMTSL3 GSN VCAN FHL1 CHAC1	2.00e-04	195	98	6	3401_UP
Drug	Spironolactone [52-01-7]; Up 200; 9.6uM; PC3; HT_HG-U133A	HSPG2 ACACB CIAO3 LRP1 WDFY3 CTSZ	2.00e-04	195	98	6	2064_UP
Drug	Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; HL60; HT_HG-U133A	AMT TBC1D9 KMT2D LRP1 WDFY3 FHL1	2.00e-04	195	98	6	2333_UP
Drug	Liothyronine [6893-02-3]; Down 200; 6.2uM; MCF7; HT_HG-U133A	ENGASE AMT ITFG2 CNTRL ZNF276 OSMR	2.00e-04	195	98	6	4947_DN
Drug	acetonitrile	FAT1 PROZ CIAO3 IGSF3	2.01e-04	67	98	4	CID000006342
Drug	Retrorsine [480-54-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A	FN1 ACACB GSN BTN3A3 L3MBTL1 CD22	2.06e-04	196	98	6	2784_UP
Drug	Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; PC3; HT_HG-U133A	ACACB ZNF343 ADARB1 LRP1 WDFY3 OSMR	2.06e-04	196	98	6	4587_DN
Drug	rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A	STAB2 TASL PROZ VCAN EHF WDFY3	2.06e-04	196	98	6	5593_UP
Drug	Clioquinol [130-26-7]; Down 200; 13uM; PC3; HT_HG-U133A	AMT ITFG2 CNTRL VCAN CNTNAP2 WDFY3	2.06e-04	196	98	6	4663_DN
Drug	Mesoridazine besylate [32672-69-8]; Down 200; 7.4uM; PC3; HT_HG-U133A	ENGASE ACACB ITFG2 CUL9 CPT2 CHAC1	2.06e-04	196	98	6	7256_DN
Drug	Sulindac [38194-50-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A	AMT FN1 CUL9 VCAN WDFY3 SEPTIN7	2.11e-04	197	98	6	5528_UP
Drug	Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; PC3; HT_HG-U133A	ITFG2 CUL9 CPT2 VCAN CNTNAP2 CTSZ	2.11e-04	197	98	6	3752_DN
Drug	Hymecromone [90-33-5]; Up 200; 22.8uM; HL60; HT_HG-U133A	SPTBN5 KMT2D ZNF276 L3MBTL1 CNTNAP2 LRP1	2.11e-04	197	98	6	3045_UP
Drug	Myricetin [529-44-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A	ITFG2 CNTRL ADARB1 RGS12 GSN FHL1	2.11e-04	197	98	6	3270_DN
Drug	Clonidine hydrochloride [4205-91-8]; Up 200; 15uM; PC3; HT_HG-U133A	HSPG2 TASL RGS12 L3MBTL1 VCAN LRP1	2.11e-04	197	98	6	4478_UP
Drug	Acyclovir [59277-89-3]; Up 200; 17.8uM; MCF7; HT_HG-U133A	COL3A1 FN1 TASL ADARB1 GSN FHL1	2.11e-04	197	98	6	1543_UP
Drug	Dacarbazine [4342-03-4]; Up 200; 22uM; PC3; HT_HG-U133A	COL3A1 HSPG2 ACACB SPTBN5 CD22 CTSZ	2.11e-04	197	98	6	4480_UP
Drug	(d,l)-Tetrahydroberberine [522-97-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A	HSPG2 ACACB CNTRL CUL9 F12 WDFY3	2.11e-04	197	98	6	4138_UP
Drug	Thioproperazine dimesylate [2347-80-0]; Down 200; 6.2uM; PC3; HT_HG-U133A	AMT ITFG2 CPT2 TBC1D9 WDFY3 OSMR	2.11e-04	197	98	6	5791_DN
Drug	3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A	LAMB4 STAB2 RGS12 VCAN FHL1 CHAC1	2.11e-04	197	98	6	4764_UP
Drug	Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; HL60; HT_HG-U133A	GALNT2 ACACB ADARB1 F12 TBC1D9 VCAN	2.11e-04	197	98	6	2205_DN
Drug	Pridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; PC3; HT_HG-U133A	FN1 ACACB TASL RGS12 L3MBTL1 VCAN	2.11e-04	197	98	6	5860_UP
Drug	Sulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A	LAMB4 CUL9 RGS12 ELMO1 L3MBTL1 CTSZ	2.11e-04	197	98	6	3616_UP
Drug	2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A	ITFG2 PLA2G3 GSN CD22 CNTNAP2 FHL1	2.11e-04	197	98	6	5600_DN
Drug	LY 294002; Down 200; 10uM; HL60; HT_HG-U133A	FN1 CPT2 CIAO3 VCAN CTSZ CHAC1	2.11e-04	197	98	6	1180_DN
Drug	Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A	HSPG2 ADAMTSL3 F12 RGS12 GSN EHF	2.11e-04	197	98	6	4690_UP
Drug	3-nitropropionic acid; Down 200; 10uM; PC3; HT_HG-U133A	COL3A1 CUL9 CPT2 TASL ADARB1 ZNF276	2.11e-04	197	98	6	6372_DN
Drug	(R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A	AMT STAB2 FN1 CUL9 OSMR FHL1	2.17e-04	198	98	6	6096_DN
Drug	Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A	FN1 HPSE2 TASL ELMO1 L3MBTL1 CD22	2.17e-04	198	98	6	3624_UP
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HG-U133A	AMT GALNT2 CNTRL LARS2 ADARB1 MED23	2.17e-04	198	98	6	762_UP
Drug	(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; MCF7; HT_HG-U133A	COL3A1 ACACB CUL9 PROZ OSMR CTSZ	2.17e-04	198	98	6	3384_UP
Drug	vinblastine sulfate; Down 200; 0.1uM; MCF7; HT_HG-U133A	ITFG2 CNTRL LGR4 RGS12 VCAN WDFY3	2.17e-04	198	98	6	7517_DN
Drug	Etofenamate [30544-47-9]; Up 200; 10.8uM; MCF7; HT_HG-U133A	ITFG2 PLA2G3 CUL9 TASL RGS12 CTSZ	2.17e-04	198	98	6	7327_UP
Drug	Pentolinium bitartrate [52-62-0]; Down 200; 7.4uM; MCF7; HT_HG-U133A	HSPG2 STAB2 ITFG2 PLA2G3 POMGNT1 CUL9	2.17e-04	198	98	6	2305_DN
Drug	Bacitracin [1405-87-4]; Up 200; 2.8uM; HL60; HT_HG-U133A	FN1 LGR4 RGS12 L3MBTL1 CIAO3 FHL1	2.17e-04	198	98	6	3109_UP
Drug	Betonicine [515-25-3]; Down 200; 25.2uM; MCF7; HT_HG-U133A	AMT STAB2 ACACB ADAMTSL3 RGS12 SEPTIN7	2.17e-04	198	98	6	3642_DN
Drug	Nitrofurantoin [67-20-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A	STAB2 ITFG2 CUL9 RGS12 GSN OSMR	2.17e-04	198	98	6	2303_DN
Drug	Austricine [10180-88-8]; Up 200; 14.2uM; HL60; HT_HG-U133A	ACACB ITFG2 PLA2G3 NBN ANKRA2 SEPTIN7	2.17e-04	198	98	6	2157_UP
Drug	Nafcillin sodium salt monohydrate [7177-50-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A	HSPG2 ACACB PLA2G3 CNTRL PROZ VCAN	2.17e-04	198	98	6	4103_UP
Drug	Ethamsylate [2624-44-4]; Down 200; 15.2uM; PC3; HT_HG-U133A	HSPG2 ACACB ITFG2 ZNF276 VCAN LRP1	2.17e-04	198	98	6	4576_DN
Drug	Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; MCF7; HT_HG-U133A	AMT HPSE2 CD22 CNTNAP2 OSMR CTSZ	2.17e-04	198	98	6	3550_UP
Drug	ICI 182,780; Up 200; 0.01uM; PC3; HT_HG-U133A	PCSK2 ITFG2 CUL9 SPTBN5 PROZ LRP2BP	2.17e-04	198	98	6	4462_UP
Drug	Rimexolone [49697-38-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A	COL3A1 CUL9 RGS12 L3MBTL1 CNTNAP2 CTSZ	2.23e-04	199	98	6	3516_UP
Drug	Gliquidone [33342-05-1]; Up 200; 7.6uM; MCF7; HT_HG-U133A	CUL9 HPSE2 RGS12 L3MBTL1 LRP1 SIGLEC1	2.23e-04	199	98	6	6505_UP
Drug	Oxaprozin [21256-18-8]; Up 200; 13.6uM; PC3; HT_HG-U133A	COL3A1 FRAS1 HPSE2 RGS12 TBC1D9 SPTBN5	2.23e-04	199	98	6	3794_UP
Drug	Bumetanide [28395-03-1]; Up 200; 11uM; MCF7; HT_HG-U133A	STAB2 SPTBN5 BTN3A3 L3MBTL1 OSMR SEPTIN7	2.23e-04	199	98	6	5542_UP
Drug	Chlorambucil [305-03-3]; Down 200; 13.2uM; PC3; HT_HG-U133A	ITFG2 CUL9 TBC1D9 CNTNAP2 CTSZ CHAC1	2.23e-04	199	98	6	4523_DN
Drug	Rolitetracycline [751-97-3]; Up 200; 7.6uM; PC3; HT_HG-U133A	LAMB4 TASL RGS12 L3MBTL1 VCAN CNTNAP2	2.23e-04	199	98	6	6731_UP
Drug	Heliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A	ACACB ADARB1 ELMO1 BTN3A3 KMT2D L3MBTL1	2.23e-04	199	98	6	3615_UP
Drug	Berberine chloride [633-65-8]; Up 200; 10.8uM; MCF7; HT_HG-U133A	PLA2G3 CNTRL TASL PROZ FHL1 CHAC1	2.23e-04	199	98	6	6791_UP
Drug	tetraethylenepentamine pentahydrochloride; Down 200; 100uM; PC3; HG-U133A	COL3A1 FN1 ITFG2 PROZ L3MBTL1 SIGLEC1	2.23e-04	199	98	6	457_DN
Drug	Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; HL60; HT_HG-U133A	HPSE2 RGS12 SPTBN5 L3MBTL1 CNTNAP2 SEPTIN7	2.23e-04	199	98	6	3032_UP
Disease	Schizophrenia	COL3A1 LAMA1 BTBD9 LARS2 ADAMTSL3 ADARB1 RGS12 GSN CYFIP1 CNTNAP2 LRP1 PPP1R9B SEPTIN7	6.48e-06	883	97	13	C0036341
Disease	cadherin-15 measurement	GALNT2 F12	2.22e-04	7	97	2	EFO_0020211
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP2 CNTNAP4	2.96e-04	8	97	2	DOID:0060308 (implicated_via_orthology)
Disease	Aortic Valve Insufficiency	COL3A1 FN1	5.77e-04	11	97	2	C0003504
Disease	intracranial aneurysm (is_implicated_in)	KMT2D VCAN	6.91e-04	12	97	2	DOID:10941 (is_implicated_in)
Disease	platelet component distribution width	COL3A1 USP49 GALNT2 ELMO1 CYFIP1 LSM4 PPP1R9B SIGLEC1 CTSZ	8.63e-04	755	97	9	EFO_0007984
Disease	autism spectrum disorder (is_implicated_in)	CYFIP1 CNTNAP2	1.25e-03	16	97	2	DOID:0060041 (is_implicated_in)
Disease	migraine without aura, susceptibility to, 4	HPSE2 LRP1	1.25e-03	16	97	2	MONDO_0011847
Disease	family history of Alzheimer’s disease	CLPTM1 CNTNAP2 CEACAM20	1.67e-03	71	97	3	EFO_0009268
Disease	myocardial infarction (biomarker_via_orthology)	COL3A1 FN1 GSN VCAN	1.95e-03	160	97	4	DOID:5844 (biomarker_via_orthology)
Disease	stem Cell Growth Factor beta measurement	STAB2 F12 CNTNAP2	1.96e-03	75	97	3	EFO_0008292
Disease	partial thromboplastin time	F12 C1S	2.82e-03	24	97	2	EFO_0004310
Disease	Ureteral obstruction	COL3A1 FN1	2.82e-03	24	97	2	C0041956
Disease	migraine disorder, diastolic blood pressure	ARID4A HPSE2	3.05e-03	25	97	2	EFO_0006336, MONDO_0005277
Disease	Left Ventricular Hypertrophy	COL3A1 FN1	3.05e-03	25	97	2	C0149721
Disease	cigarettes per day measurement	DGKZ ADARB1 RGS12 FSHR MED23 SHISA3	3.28e-03	438	97	6	EFO_0006525

Protein segments in the cluster

Peptide	Gene	Start	Entry
GTHNDTWQCQGYFTA	ABHD13	296	Q7L211
FHSGGQWCEQVEIAD	CNTRL	46	Q7Z7A1
ETASGFVAQTGVHWC	LINC00596	51	Q86U02
EVCDGWSLANHEYFA	ELMO1	36	Q92556
CAAVNAVAWCYSGSH	ATG16L2	591	Q8NAA4
YHQGGCDNIDSGAVW	ARID4A	351	P29374
GCENFTSGRHYWEVE	BTN3A3	386	O00478
TETCDYGWHKFQGQC	VCAN	3166	P13611
SCEGGNDLSVWDYAH	CTSZ	131	Q9UBR2
QNSVAYDCVQLHGGW	ACADL	376	P28330
LTWEHDGIYNCTASN	CEACAM20	406	Q6UY09
NYCEHGGECSQSWST	CNTNAP4	556	Q9C0A0
DCGVDVNEYDWNGGT	ANKRA2	236	Q9H9E1
VNFTGCNLTWQGADH	CEP78	181	Q5JTW2
GVGYAVHDNWIGCNV	CPT2	611	P23786
VHDNWIGCNVSSYPG	CPT2	616	P23786
GYVVDWCDHTQDVLG	OSMR	556	Q99650
CESQSGYVWNALVHT	PGBD4	281	Q96DM1
NCVVAGSAHAQVTWY	HSPG2	2071	P98160
ADSQFGHCFSWGENR	ACACB	696	O00763
EFTVEQCFGDGLHWA	CYFIP1	1146	Q7L576
FQSESCDDNGYHWDT	FAT1	4371	Q14517
CSAAGQVYEHGEQWS	FRAS1	221	Q86XX4
QVYEHGEQWSENACT	FRAS1	226	Q86XX4
VHEAGSQYGTWTEQC	KIAA1671	1531	Q9BY89
VWDAGHYTCEALNQA	HMCN2	2141	Q8NDA2
HEGYWEGSCSTAGCQ	KY	621	Q8NBH2
SYANETVCWVHVGDS	LRP1	236	Q07954
YECHNAGGNQEWALT	GALNT2	471	Q10471
DGYSECHDFWVNANS	L3MBTL1	341	Q9Y468
CWVHDDLNQVDVGSY	PIK3C2A	456	O00443
QFWGGLSQESHEQCI	MED23	46	Q9ULK4
AAGGRKENHQWYVCN	METTL9	46	Q9H1A3
YWHSEACGNGNLESQ	LRP2BP	196	Q9P2M1
WSDCGTQSAHSDYAD	LGR4	896	Q9BXB1
STVDAVTWQHCYIDG	HPSE2	326	Q8WWQ2
GSRSYTQAGVQWCNH	ADARB1	466	P78563
CAWDGQTYIIDHNRT	ITFG2	326	Q969R8
DAQSWCEGQGGHLVF	PKD1L2	51	Q7Z442
SGGITYQDQPWHADC	FHL1	171	Q13642
SPQDTGNYSCHVEEW	IGSF3	1071	O75054
QAGDAGTYHCTAAEW	IGSF8	261	Q969P0
DIFQHDTYCGDVWNT	CCDC127	211	Q96BQ5
NGQWYHTCGGSLIAN	CELA2B	51	P08218
HEAGSEFWADGTCSQ	FCGBP	2016	Q9Y6R7
NNGCGCWANGTYHEA	FCGBP	4406	Q9Y6R7
DGHLWCSTTSNYEQD	FN1	381	P02751
CNVSSGFFGGQWHEI	EHF	31	Q9NZC4
EDHEGCTWGVAYQVQ	CHAC1	86	Q9BUX1
GAWIGYEHTSFCGQQ	CRYBA1	71	P05813
YHCAGNGSWVNEVLG	C1S	401	P09871
LGYNHNGEWCEAQTK	ABL1	91	P00519
NGETYNGHLVSCDNW	LSM4	21	Q9Y4Z0
VTGAHCEECTVGYWG	LAMB4	481	A4D0S4
ASCGHMSQWVDDGGY	CUL9	2201	Q8IWT3
GCSHLGQSYADRDVW	COL3A1	31	P02461
CSYWADVINFDGHVV	CNTNAP2	181	Q9UHC6
DLHYWLGNECSQDES	GSN	111	P06396
CGRQLSGGWVQHCYE	ENGASE	556	Q8NFI3
GEHIWFETNVSGDFC	DGKZ	96	Q13574
NYAIDWQTGAGCDAA	FSHR	431	P23945
SEGHLYVVSNAGCWE	AMT	136	P48728
DWDSGYTCHQLGSGA	BTBD9	456	Q96Q07
QTHSNCRDYWVDTNG	ERVFC1	91	P60507
VQHSGAYWCQGTNSV	CD22	651	P20273
SQYCVSAEGVLHVWG	IFNGR1	211	P15260
TTETHWYSGETCNQG	MUC17	4371	Q685J3
ETTLCQVAGWGHQFE	F12	496	P00748
SAHDYSQQCDIWSIG	STK33	296	Q9BYT3
ANEQVDEHGCSWRSG	LARS2	216	Q15031
GGFTVNNWTEECTHL	NBN	136	O60934
CISAWNDQGYEHTAE	POMGNT1	421	Q8WZA1
GHWGYDAEVGCQACN	LAMA1	1031	P25391
DGCWSEVGDQHVGQN	MEP1A	126	Q16819
AQQSGEYCHGWVDVQ	SHISA3	21	A0PJX4
CLHNGSCQDSIWGYT	PROZ	96	P22891
SYSPGQDCVWGVHVQ	SEZ6L2	546	Q6UXD5
AAYGALCAHETAWGS	PLA2G3	81	Q9NZ20
EVDGFTATCANHQAW	SPTBN5	1216	Q9NRC6
LYTHWLQGTDSECAG	CIAO3	441	Q9H6Q4
WTSGENSDGCYEHFA	CLPTM1	136	O96005
QQYSHVSCWFENAEG	ZNF343	156	Q6P1L6
CHAAVDRWQYGDSAV	XIAP	66	P98170
SCAGTYIHVWSINGN	WDFY3	3186	Q8IZQ1
WQCGHTSDQDSYTDS	RGS12	546	O14924
IHWSCASYNEQVAGE	TASL	16	Q9HAI6
QYPWGVAEVENGEHC	SEPTIN7	266	Q16181
AEHLTSCYWGGSSNA	TBC1D9	836	Q6ZT07
SCYWGGSSNALDRHD	TBC1D9	841	Q6ZT07
YNTEGGFWVHCNDSK	USP49	621	Q70CQ1
VWGCDQGHDYTMDTS	ZNF276	231	Q8N554
GWRGVHCDNATTEDN	STAB2	1421	Q8WWQ8
AWSDAGVYTCQAENG	SIGLEC1	296	Q9BZZ2
LCEAWAFGQSHQTGV	TMEM201	286	Q5SNT2
GWTPLHEACNYGNTV	SLF1	841	Q9BQI6
ANLCEWTDYGNTFSH	ZNF790	586	Q6PG37
FSGHDGAVNAVCWSQ	WDR27	551	A2RRH5
AGNIFIDSGCHYWEV	MID2	581	Q9UJV3
GNCGKVLVWAAEYSH	UGT2B7	21	P16662
CYNSEGGFWVHCNDS	USP44	641	Q9H0E7
VWSQCSVSCGEGYHS	ADAMTSL3	1491	P82987
GAASPGFHCEWQNSY	KMT2D	1481	O14686
YWGEAQSLCQAVDEH	PPP1R9B	726	Q96SB3
TDDWFNSHGTRCAGE	PCSK2	201	P16519