Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	inositol 1,4,5-trisphosphate-gated calcium channel activity	ITPR1 ITPR2	7.73e-05	3	102	2	GO:0005220
GeneOntologyMolecularFunction	purine-rich negative regulatory element binding	ELK3 PURG	1.54e-04	4	102	2	GO:0032422
GeneOntologyMolecularFunction	alkylglycerophosphoethanolamine phosphodiesterase activity	GNA11 GNAQ	2.56e-04	5	102	2	GO:0047391
GeneOntologyMolecularFunction	G-protein beta/gamma-subunit complex binding	GNA14 GNA11 GNAQ	2.74e-04	25	102	3	GO:0031683
GeneOntologyBiologicalProcess	phospholipase C-activating dopamine receptor signaling pathway	GNA14 GNA11 GNAQ	9.94e-06	9	103	3	GO:0060158
GeneOntologyBiologicalProcess	entrainment of circadian clock	RBM4B SIK1 GNA11 GNAQ	1.45e-05	30	103	4	GO:0009649
GeneOntologyBiologicalProcess	ion channel modulating, G protein-coupled receptor signaling pathway	ITPR1 GNA11 GNAQ	2.57e-05	12	103	3	GO:0099105
GeneOntologyBiologicalProcess	phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	ITPR1 GNA11 GNAQ	3.34e-05	13	103	3	GO:0007207
HumanPheno	Choroidal melanoma	SF3B1 GNA11 GNAQ	2.94e-06	5	35	3	HP:0012054
HumanPheno	Ciliary body melanoma	SF3B1 GNA11 GNAQ	2.94e-06	5	35	3	HP:0012055
HumanPheno	Iris melanoma	SF3B1 GNA11 GNAQ	2.94e-06	5	35	3	HP:0011524
HumanPheno	Abnormal visual accommodation	SF3B1 GNA11 GNAQ	2.94e-06	5	35	3	HP:0030800
HumanPheno	Inferior lens subluxation	SF3B1 GNA11 GNAQ	2.94e-06	5	35	3	HP:0008494
HumanPheno	Abnormal ciliary body morphology	SF3B1 GNA11 GNAQ	5.86e-06	6	35	3	HP:0012776
HumanPheno	Uveal melanoma	SF3B1 GNA11 GNAQ	1.63e-05	8	35	3	HP:0007716
HumanPheno	Lens subluxation	SF3B1 GNA11 GNAQ	1.28e-04	15	35	3	HP:0001132
HumanPheno	Mydriasis	SF3B1 GNA11 GNAQ	1.57e-04	16	35	3	HP:0011499
HumanPheno	Vitreous hemorrhage	SF3B1 GNA11 GNAQ	2.26e-04	18	35	3	HP:0007902
Domain	ETS_DOMAIN_1	FLI1 ERG ETV3 ETV4 ETV3L ELK1 ELK3	1.45e-10	28	104	7	PS00345
Domain	ETS_DOMAIN_2	FLI1 ERG ETV3 ETV4 ETV3L ELK1 ELK3	1.45e-10	28	104	7	PS00346
Domain	ETS	FLI1 ERG ETV3 ETV4 ETV3L ELK1 ELK3	1.45e-10	28	104	7	SM00413
Domain	Ets_dom	FLI1 ERG ETV3 ETV4 ETV3L ELK1 ELK3	1.45e-10	28	104	7	IPR000418
Domain	ETS_DOMAIN_3	FLI1 ERG ETV3 ETV4 ETV3L ELK1 ELK3	1.45e-10	28	104	7	PS50061
Domain	Ets	FLI1 ERG ETV3 ETV4 ETV3L ELK1 ELK3	1.45e-10	28	104	7	PF00178
Domain	Gprotein_alpha_Q	GNA14 GNA11 GNAQ	6.68e-07	4	104	3	IPR000654
Domain	ETV3	ETV3 ETV3L	3.07e-05	2	104	2	IPR032929
Domain	Cadherin_tail	PCDHA9 PCDHA13 PCDHA12 PCDHGA8	5.20e-05	37	104	4	PF15974
Domain	Cadherin_CBD	PCDHA9 PCDHA13 PCDHA12 PCDHGA8	5.20e-05	37	104	4	IPR031904
Domain	LY	LRP1 ROS1 SORL1	7.27e-05	15	104	3	SM00135
Domain	LDLR_classB_rpt	LRP1 ROS1 SORL1	7.27e-05	15	104	3	IPR000033
Domain	G-alpha	GNA14 GNA11 GNAQ	8.91e-05	16	104	3	PF00503
Domain	GproteinA_insert	GNA14 GNA11 GNAQ	8.91e-05	16	104	3	IPR011025
Domain	-	GNA14 GNA11 GNAQ	8.91e-05	16	104	3	1.10.400.10
Domain	G_alpha	GNA14 GNA11 GNAQ	8.91e-05	16	104	3	SM00275
Domain	InsP3_rcpt-bd	ITPR1 ITPR2	9.18e-05	3	104	2	IPR000493
Domain	SSDP_DNA-bd	SSBP2 SSBP4	9.18e-05	3	104	2	IPR008116
Domain	Gprotein_alpha_su	GNA14 GNA11 GNAQ	1.08e-04	17	104	3	IPR001019
Domain	-	FLI1 ERG ETV3 ETV4 ETV3L ELK1 ELK3	2.18e-04	218	104	7	1.10.10.10
Domain	Cadherin_CS	PCDHA9 PCDHA13 PCDHA12 PCDH15 PCDHGA8	3.59e-04	109	104	5	IPR020894
Domain	WHTH_DNA-bd_dom	FLI1 ERG ETV3 ETV4 ETV3L ELK1 ELK3	4.11e-04	242	104	7	IPR011991
Domain	CADHERIN_1	PCDHA9 PCDHA13 PCDHA12 PCDH15 PCDHGA8	4.24e-04	113	104	5	PS00232
Domain	Cadherin	PCDHA9 PCDHA13 PCDHA12 PCDH15 PCDHGA8	4.24e-04	113	104	5	PF00028
Domain	CADHERIN_2	PCDHA9 PCDHA13 PCDHA12 PCDH15 PCDHGA8	4.41e-04	114	104	5	PS50268
Domain	-	PCDHA9 PCDHA13 PCDHA12 PCDH15 PCDHGA8	4.41e-04	114	104	5	2.60.40.60
Domain	RIH_assoc	ITPR1 ITPR2	4.54e-04	6	104	2	PF08454
Domain	RIH_assoc-dom	ITPR1 ITPR2	4.54e-04	6	104	2	IPR013662
Domain	RIH_dom	ITPR1 ITPR2	4.54e-04	6	104	2	IPR000699
Domain	Ins145_P3_rcpt	ITPR1 ITPR2	4.54e-04	6	104	2	IPR014821
Domain	Ryanodine_recept-rel	ITPR1 ITPR2	4.54e-04	6	104	2	IPR015925
Domain	-	ITPR1 ITPR2	4.54e-04	6	104	2	1.25.10.30
Domain	RYDR_ITPR	ITPR1 ITPR2	4.54e-04	6	104	2	PF01365
Domain	Ins145_P3_rec	ITPR1 ITPR2	4.54e-04	6	104	2	PF08709
Domain	CA	PCDHA9 PCDHA13 PCDHA12 PCDH15 PCDHGA8	4.59e-04	115	104	5	SM00112
Domain	Cadherin_2	PCDHA9 PCDHA13 PCDHA12 PCDHGA8	4.73e-04	65	104	4	PF08266
Domain	Cadherin_N	PCDHA9 PCDHA13 PCDHA12 PCDHGA8	4.73e-04	65	104	4	IPR013164
Domain	Cadherin-like	PCDHA9 PCDHA13 PCDHA12 PCDH15 PCDHGA8	4.78e-04	116	104	5	IPR015919
Domain	Cadherin	PCDHA9 PCDHA13 PCDHA12 PCDH15 PCDHGA8	5.17e-04	118	104	5	IPR002126
Domain	P-loop_NTPase	DNAH3 HS6ST2 DDX60 RNF213 MYO1B PFKFB4 GNA14 TJP1 MYO3B GNA11 GNAQ SEPTIN7 DNAH9	8.53e-04	848	104	13	IPR027417
Domain	-	LRP1 ROS1 SORL1	1.33e-03	39	104	3	2.120.10.30
Domain	MIR	ITPR1 ITPR2	1.34e-03	10	104	2	PS50919
Domain	MIR	ITPR1 ITPR2	1.34e-03	10	104	2	PF02815
Domain	MIR	ITPR1 ITPR2	1.34e-03	10	104	2	SM00472
Domain	MIR_motif	ITPR1 ITPR2	1.34e-03	10	104	2	IPR016093
Domain	PNT	FLI1 ERG	1.63e-03	11	104	2	PS51433
Domain	Pointed_dom	FLI1 ERG	1.63e-03	11	104	2	IPR003118
Domain	SAM_PNT	FLI1 ERG	1.63e-03	11	104	2	PF02198
Domain	SAM_PNT	FLI1 ERG	1.63e-03	11	104	2	SM00251
Domain	Sulfotransfer_2	HS6ST2 CHST9	1.95e-03	12	104	2	PF03567
Domain	Sulfotransferase	HS6ST2 CHST9	1.95e-03	12	104	2	IPR005331
Domain	Quinoprot_gluc/sorb_DH	OLFM4 LRP1	1.95e-03	12	104	2	IPR011041
Domain	6-blade_b-propeller_TolB-like	LRP1 ROS1 SORL1	2.14e-03	46	104	3	IPR011042
Domain	OLF	OLFML2B OLFM4	2.30e-03	13	104	2	PS51132
Domain	Olfac-like_dom	OLFML2B OLFM4	2.30e-03	13	104	2	IPR003112
Domain	OLF	OLFML2B OLFM4	2.30e-03	13	104	2	SM00284
Domain	OLF	OLFML2B OLFM4	2.30e-03	13	104	2	PF02191
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH9	2.68e-03	14	104	2	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH9	2.68e-03	14	104	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH9	2.68e-03	14	104	2	IPR013602
Domain	DHC_N2	DNAH3 DNAH9	2.68e-03	14	104	2	PF08393
Domain	MT	DNAH3 DNAH9	2.68e-03	14	104	2	PF12777
Domain	AAA_8	DNAH3 DNAH9	2.68e-03	14	104	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH3 DNAH9	2.68e-03	14	104	2	IPR011704
Domain	Ldl_recept_b	LRP1 SORL1	2.68e-03	14	104	2	PF00058
Domain	LDLRB	LRP1 SORL1	2.68e-03	14	104	2	PS51120
Domain	AAA_5	DNAH3 DNAH9	2.68e-03	14	104	2	PF07728
Domain	DHC_fam	DNAH3 DNAH9	3.08e-03	15	104	2	IPR026983
Domain	Dynein_heavy_dom	DNAH3 DNAH9	3.08e-03	15	104	2	IPR004273
Domain	Dynein_heavy	DNAH3 DNAH9	3.08e-03	15	104	2	PF03028
Pathway	WP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA	ITPR1 GNA14 GNA11 GNAQ	4.04e-06	22	71	4	M39795
Pathway	KEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY	ITPR1 ITPR2 GNA14 GNA11 GNAQ	4.99e-06	50	71	5	M47951
Pathway	PID_S1P_S1P2_PATHWAY	GNA14 GNA11 ELK1 GNAQ	5.82e-06	24	71	4	M268
Pathway	REACTOME_ACETYLCHOLINE_REGULATES_INSULIN_SECRETION	GNA14 GNA11 GNAQ	6.73e-06	8	71	3	MM15032
Pathway	REACTOME_FATTY_ACIDS_BOUND_TO_GPR40_FFAR1_REGULATE_INSULIN_SECRETION	GNA14 GNA11 GNAQ	6.73e-06	8	71	3	M27356
Pathway	REACTOME_FATTY_ACIDS_BOUND_TO_GPR40_FFAR1_REGULATE_INSULIN_SECRETION	GNA14 GNA11 GNAQ	6.73e-06	8	71	3	MM15100
Pathway	REACTOME_G_PROTEIN_MEDIATED_EVENTS	ITPR1 ITPR2 GNA14 GNA11 GNAQ	7.33e-06	54	71	5	M26911
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	ITPR1 ITPR2 GNA14 GNA11 GNAQ	1.34e-05	61	71	5	MM15071
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY	ITPR1 ITPR2 GNAQ	1.43e-05	10	71	3	M47661
Pathway	REACTOME_ACETYLCHOLINE_REGULATES_INSULIN_SECRETION	GNA14 GNA11 GNAQ	1.43e-05	10	71	3	M1825
Pathway	REACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION	GNA14 GNA11 GNAQ	1.96e-05	11	71	3	M27317
Pathway	REACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION	GNA14 GNA11 GNAQ	1.96e-05	11	71	3	MM15035
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY	ITPR1 ITPR2 GNAQ	1.96e-05	11	71	3	M49033
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	ITPR1 ITPR2 GNA14 GNA11 GNAQ	3.03e-05	72	71	5	MM14631
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY	ITPR1 ITPR2 GNAQ	3.38e-05	13	71	3	M47656
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	ITPR1 ITPR2 GNA14 GNA11 GNAQ	4.46e-05	78	71	5	M1921
Pathway	PID_THROMBIN_PAR4_PATHWAY	GNA14 GNA11 GNAQ	5.33e-05	15	71	3	M138
Pathway	REACTOME_OPIOID_SIGNALLING	ITPR1 ITPR2 GNA14 GNA11 GNAQ	8.86e-05	90	71	5	M6467
Pathway	KEGG_GAP_JUNCTION	ITPR1 ITPR2 TJP1 GNA11 GNAQ	8.86e-05	90	71	5	M4013
Pathway	WP_SEROTONIN_RECEPTOR_2_AND_ELKSRFGATA4_SIGNALING	ITPR1 ELK1 GNAQ	1.31e-04	20	71	3	M39485
Pathway	KEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR2 GNAQ	1.31e-04	20	71	3	M47688
Pathway	KEGG_MEDICUS_REFERENCE_GNRH_GNRHR_PLCB_PKC_SIGNALING_PATHWAY	GNA11 ELK1 GNAQ	1.53e-04	21	71	3	M47638
Pathway	PID_S1P_META_PATHWAY	GNA14 GNA11 GNAQ	1.53e-04	21	71	3	M155
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR2 GNAQ	1.53e-04	21	71	3	M47689
Pathway	KEGG_GNRH_SIGNALING_PATHWAY	ITPR1 ITPR2 GNA11 ELK1 GNAQ	1.53e-04	101	71	5	M1979
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR2 GNAQ	1.76e-04	22	71	3	M47690
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR2 GNAQ	1.76e-04	22	71	3	M47675
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR2 GNAQ	2.02e-04	23	71	3	M47676
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	ITPR1 ITPR2 GNA14 GNA11 GNAQ	2.09e-04	108	71	5	M17034
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNA14 GNA11 GNAQ	2.30e-04	24	71	3	M13115
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNA14 GNA11 GNAQ	2.30e-04	24	71	3	MM15088
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNA14 GNA11 GNAQ	2.30e-04	24	71	3	M18308
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNA14 GNA11 GNAQ	2.30e-04	24	71	3	MM14794
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY	ITPR1 ITPR2	2.48e-04	5	71	2	M49000
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNA14 GNA11 GNAQ	2.60e-04	25	71	3	MM15056
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNA14 GNA11 GNAQ	2.60e-04	25	71	3	M811
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	ERBB4 ITPR1 ITPR2 GNA14 GNA11 GNAQ	2.70e-04	178	71	6	M2890
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY	GNA11 GNAQ	3.70e-04	6	71	2	M47548
Pathway	KEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY	ITPR1 ITPR2	3.70e-04	6	71	2	M47960
Pathway	PID_S1P_S1P3_PATHWAY	GNA14 GNA11 GNAQ	4.07e-04	29	71	3	M55
Pathway	KEGG_LONG_TERM_DEPRESSION	ITPR1 ITPR2 GNA11 GNAQ	4.22e-04	70	71	4	M8232
Pathway	WP_ALZHEIMERS_DISEASE	ITPR1 ITPR2 LRP1 GNAQ	5.21e-04	74	71	4	MM15962
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNA14 GNA11 GNAQ	5.47e-04	32	71	3	M861
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNA14 GNA11 GNAQ	5.47e-04	32	71	3	MM15148
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNA14 GNA11 GNAQ	5.99e-04	33	71	3	MM15020
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNA14 GNA11 GNAQ	5.99e-04	33	71	3	M9379
Pathway	PID_ARF6_PATHWAY	GNA14 GNA11 GNAQ	7.14e-04	35	71	3	M86
Pathway	WP_SEROTONIN_HTR1_GROUP_AND_FOS_PATHWAY	ITPR1 ELK1 GNAQ	8.41e-04	37	71	3	M42558
Pathway	KEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY	ITPR1 ITPR2	8.80e-04	9	71	2	M47852
Pathway	KEGG_MEDICUS_REFERENCE_LPA_GNAQ_11_RHOA_SIGNALING_PATHWAY	GNA11 GNAQ	8.80e-04	9	71	2	M47732
Pathway	REACTOME_COOPERATION_OF_PDCL_PHLP1_AND_TRIC_CCT_IN_G_PROTEIN_BETA_FOLDING	GNA14 GNA11 GNAQ	9.10e-04	38	71	3	M27656
Pathway	REACTOME_G_PROTEIN_MEDIATED_EVENTS	GNA14 GNA11 GNAQ	9.82e-04	39	71	3	MM14496
Pathway	REACTOME_CHAPERONIN_MEDIATED_PROTEIN_FOLDING	GNA14 GNA11 GNAQ	9.82e-04	39	71	3	MM15003
Pathway	PID_ER_NONGENOMIC_PATHWAY	GNA14 GNA11 GNAQ	1.06e-03	40	71	3	M41
Pathway	WP_G_PROTEIN_SIGNALING_PATHWAYS	ITPR1 GNA14 GNA11 GNAQ	1.09e-03	90	71	4	MM15882
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS	DSP TJP1	1.10e-03	10	71	2	MM14956
Pathway	WP_G_PROTEIN_SIGNALING	ITPR1 GNA14 GNA11 GNAQ	1.14e-03	91	71	4	M39426
Pathway	PID_THROMBIN_PAR1_PATHWAY	GNA14 GNA11 GNAQ	1.31e-03	43	71	3	M238
Pathway	KEGG_MEDICUS_REFERENCE_KISS1_KISS1R_PLCB_PKC_SIGNALING_PATHWAY	GNA11 GNAQ	1.34e-03	11	71	2	M47637
Pathway	REACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION	ITPR1 ITPR2	1.34e-03	11	71	2	M27466
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS	DSP TJP1	1.34e-03	11	71	2	M9990
Pathway	WP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS	ITPR1 ITPR2 GNAQ	1.40e-03	44	71	3	M39845
Pathway	KEGG_MEDICUS_REFERENCE_TRH_TRHR_PLCB_PKC_SIGNALING_PATHWAY	GNA11 GNAQ	1.60e-03	12	71	2	M47649
Pathway	WP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING	ITPR1 GNAQ	1.88e-03	13	71	2	M39589
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR2	1.88e-03	13	71	2	M47696
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR2	1.88e-03	13	71	2	M47751
Pathway	REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS	ITPR1 ITPR2	1.88e-03	13	71	2	MM14553
Pathway	WP_ALZHEIMERS_DISEASE	PSMB5 KLC4 ITPR1 ITPR2 LRP1 GNAQ	1.99e-03	261	71	6	M42565
Pathway	REACTOME_METABOLISM_OF_CARBOHYDRATES	GPC1 FUT10 HS6ST2 CHST9 PFKFB4 NUP188	2.40e-03	271	71	6	MM15406
Pathway	KEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY	ERBB4 ITPR1 ITPR2	2.66e-03	55	71	3	M47952
Pathway	KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	ITPR1 ITPR2 GNA11 GNAQ	2.68e-03	115	71	4	M9387
Pathway	PID_TXA2PATHWAY	GNA14 GNA11 GNAQ	2.80e-03	56	71	3	M99
Pathway	WP_ID_SIGNALING	ELK1 ELK3	2.87e-03	16	71	2	M39359
Pathway	REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS	ITPR1 ITPR2	2.87e-03	16	71	2	M26945
Pathway	REACTOME_METABOLISM_OF_CARBOHYDRATES	GPC1 FUT10 HS6ST2 CHST9 PFKFB4 NUP188	3.25e-03	288	71	6	M16864
Pubmed	ETS-family genes in pancreatic development.	FLI1 ERG ETV3 ETV4 ELK1 ELK3	2.94e-10	29	105	6	17907201
Pubmed	Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle.	ITPR1 ITPR2 GNA14 GNA11 GNAQ	6.68e-10	15	105	5	28578927
Pubmed	ETS-dependent regulation of a distal Gata4 cardiac enhancer.	FLI1 ERG ETV3 ETV4 ELK3	9.25e-09	24	105	5	22056786
Pubmed	Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.	FLI1 ERG ETV3 ELK1 ELK3	2.55e-08	29	105	5	26097038
Pubmed	High frequency of GNA14, GNAQ, and GNA11 mutations in cherry hemangioma: a histopathological and molecular study of 85 cases indicating GNA14 as the most commonly mutated gene in vascular neoplasms.	GNA14 GNA11 GNAQ	2.67e-08	3	105	3	31189994
Pubmed	Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo.	FLI1 ERG ETV4	1.07e-07	4	105	3	20517297
Pubmed	Promiscuous coupling of receptors to Gq class alpha subunits and effector proteins in pancreatic and submandibular gland cells.	GNA14 GNA11 GNAQ	1.07e-07	4	105	3	9765251
Pubmed	Genomic Profiling of Metastatic Uveal Melanoma Shows Frequent Coexisting BAP1 or SF3B1 and GNAQ/GNA11 Mutations and Correlation With Prognosis.	SF3B1 GNA11 GNAQ	1.07e-07	4	105	3	35212356
Pubmed	Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice.	GNA14 GNA11 GNAQ	1.07e-07	4	105	3	9687499
Pubmed	Comparative analysis of the GNAQ, GNA11, SF3B1, and EIF1AX driver mutations in melanoma and across the cancer spectrum.	SF3B1 GNA11 GNAQ	1.07e-07	4	105	3	27089234
Pubmed	Loss of gq/11 genes does not abolish melanopsin phototransduction.	GNA14 GNA11 GNAQ	2.66e-07	5	105	3	24870805
Pubmed	Chromosome 3 status combined with BAP1 and EIF1AX mutation profiles are associated with metastasis in uveal melanoma.	SF3B1 GNA11 GNAQ	2.66e-07	5	105	3	24970262
Pubmed	An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion.	ITPR1 GNA11 GNAQ	2.66e-07	5	105	3	26075576
Pubmed	Using siRNA to define functional interactions between melanopsin and multiple G Protein partners.	GNA14 GNA11 GNAQ	5.31e-07	6	105	3	24958088
Pubmed	A novel zinc finger gene is fused to EWS in small round cell tumor.	FLI1 ERG ETV4	5.31e-07	6	105	3	10949935
Pubmed	Mutations of GNAQ, GNA11, SF3B1, EIF1AX, PLCB4 and CYSLTR in Uveal Melanoma in Chinese Patients.	SF3B1 GNA11 GNAQ	5.31e-07	6	105	3	31614358
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	DSP VPS13C PSMB5 RNF213 MYO1B SF3B1 TJP1 NUP188	1.46e-06	264	105	8	32814769
Pubmed	Protease-activated receptors in hemostasis, thrombosis and vascular biology.	GNA14 GNA11 GNAQ	2.22e-06	9	105	3	16102047
Pubmed	Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11, its physiologic regulator.	GNA14 GNA11 GNAQ	2.22e-06	9	105	3	1322796
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CFAP47 ATRN LAMB4 DNAH3 DSP VPS13C NEXMIF RNF213 ITPR2 MYO3B NUP188 DOP1B	2.39e-06	736	105	12	29676528
Pubmed	Analysis of G protein alpha subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach.	GNA14 GNA11 GNAQ	3.16e-06	10	105	3	8588930
Pubmed	Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.	PCDHA9 PCDHA13 PCDHA12	4.33e-06	11	105	3	9655502
Pubmed	Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2.	FLI1 ERG ELK3	7.48e-06	13	105	3	25802403
Pubmed	GNAQ and GNA11 mutations occur in 9.5% of mucosal melanoma and are associated with poor prognosis.	GNA11 GNAQ	9.03e-06	2	105	2	27498141
Pubmed	The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan.	GNA11 GNAQ	9.03e-06	2	105	2	28248732
Pubmed	Uveal Melanoma: GNAQ and GNA11 Mutations in a Greek Population.	GNA11 GNAQ	9.03e-06	2	105	2	28982892
Pubmed	Mutations in GNA11 in uveal melanoma.	GNA11 GNAQ	9.03e-06	2	105	2	21083380
Pubmed	Activation of Gq/11 in the mouse corpus luteum is required for parturition.	GNA11 GNAQ	9.03e-06	2	105	2	25495873
Pubmed	ERG and FLI1 protein expression in epithelioid sarcoma.	FLI1 ERG	9.03e-06	2	105	2	24072183
Pubmed	GNAQ and GNA11 mutations in uveal melanoma.	GNA11 GNAQ	9.03e-06	2	105	2	25304237
Pubmed	Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes.	GNA11 GNAQ	9.03e-06	2	105	2	28301547
Pubmed	Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation.	GNA11 GNAQ	9.03e-06	2	105	2	16847339
Pubmed	Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology.	GNA11 GNAQ	9.03e-06	2	105	2	29570931
Pubmed	Muscarinic inhibition of calcium current and M current in Galpha q-deficient mice.	GNA11 GNAQ	9.03e-06	2	105	2	10818132
Pubmed	Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis.	GNA11 GNAQ	9.03e-06	2	105	2	26272756
Pubmed	NK2 receptor-mediated detrusor muscle contraction involves Gq/11-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathway.	GNA11 GNAQ	9.03e-06	2	105	2	31461351
Pubmed	Synergistic Role of Endothelial ERG and FLI1 in Mediating Pulmonary Vascular Homeostasis.	FLI1 ERG	9.03e-06	2	105	2	28248553
Pubmed	Ultradeep sequencing detects GNAQ and GNA11 mutations in cell-free DNA from plasma of patients with uveal melanoma.	GNA11 GNAQ	9.03e-06	2	105	2	23634288
Pubmed	Frequent GNAQ and GNA14 Mutations in Hepatic Small Vessel Neoplasm.	GNA14 GNAQ	9.03e-06	2	105	2	29975248
Pubmed	Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism.	GNA11 GNAQ	9.03e-06	2	105	2	26368812
Pubmed	Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to cholecystokinin are mediated by a transient receptor potential-like current.	GNA11 GNAQ	9.03e-06	2	105	2	17482476
Pubmed	Molecular genetic testing of uveal melanoma from routinely processed and stained cytology specimens.	GNA11 GNAQ	9.03e-06	2	105	2	21945171
Pubmed	Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations.	GNA11 GNAQ	9.03e-06	2	105	2	24141786
Pubmed	An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.	ITPR1 ITPR2	9.03e-06	2	105	2	18708078
Pubmed	Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association.	GNA11 GNAQ	9.03e-06	2	105	2	9175863
Pubmed	Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.	ITPR1 ITPR2	9.03e-06	2	105	2	15201137
Pubmed	Recurrent GNA14 mutations in anastomosing haemangiomas.	GNA14 GNAQ	9.03e-06	2	105	2	29574926
Pubmed	The ethnic profile of patients with birthmarks reveals interaction of germline and postzygotic genetics.	GNA11 GNAQ	9.03e-06	2	105	2	28083870
Pubmed	Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.	ITPR1 ITPR2	9.03e-06	2	105	2	23582047
Pubmed	Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation.	GNA11 GNAQ	9.03e-06	2	105	2	37102682
Pubmed	Gq/11-Dependent Changes in the Murine Ovarian Transcriptome at the End of Gestation.	GNA11 GNAQ	9.03e-06	2	105	2	26843449
Pubmed	Direct targeting of Gαq and Gα11 oncoproteins in cancer cells.	GNA11 GNAQ	9.03e-06	2	105	2	30890659
Pubmed	Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways.	GNA11 GNAQ	9.03e-06	2	105	2	7492305
Pubmed	Reduced trabecular bone mass and strength in mice overexpressing Gα11 protein in cells of the osteoblast lineage.	GNA11 GNAQ	9.03e-06	2	105	2	24308950
Pubmed	The Ets family member Erg gene is expressed in mesodermal tissues and neural crests at fundamental steps during mouse embryogenesis.	FLI1 ERG	9.03e-06	2	105	2	10704859
Pubmed	Gαq and Gα11 contribute to the maintenance of cellular electrophysiology and Ca2+ handling in ventricular cardiomyocytes.	GNA11 GNAQ	9.03e-06	2	105	2	22562663
Pubmed	Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transition.	FLI1 ERG	9.03e-06	2	105	2	30500808
Pubmed	Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage.	FLI1 ERG	9.03e-06	2	105	2	19666492
Pubmed	Transdifferentiation of erythroblasts to megakaryocytes using FLI1 and ERG transcription factors.	FLI1 ERG	9.03e-06	2	105	2	26063314
Pubmed	Functional specificity of G alpha q and G alpha 11 in the cholinergic and glutamatergic modulation of potassium currents and excitability in hippocampal neurons.	GNA11 GNAQ	9.03e-06	2	105	2	11826096
Pubmed	Blue nevi and variants: an update.	GNA11 GNAQ	9.03e-06	2	105	2	21366456
Pubmed	In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations.	GNA11 GNAQ	9.03e-06	2	105	2	35580369
Pubmed	Gonadotropin and gonadal steroid release in response to a gonadotropin-releasing hormone agonist in Gqalpha and G11alpha knockout mice.	GNA11 GNAQ	9.03e-06	2	105	2	9607776
Pubmed	Reverse Phenotyping in Patients with Skin Capillary Malformations and Mosaic GNAQ or GNA11 Mutations Defines a Clinical Spectrum with Genotype-Phenotype Correlation.	GNA11 GNAQ	9.03e-06	2	105	2	31726051
Pubmed	Papillary Hemangioma Harbors Somatic GNA11 and GNAQ Mutations.	GNA11 GNAQ	9.03e-06	2	105	2	37750536
Pubmed	G(alpha)q-deficient mice lack metabotropic glutamate receptor-dependent long-term depression but show normal long-term potentiation in the hippocampal CA1 region.	GNA11 GNAQ	9.03e-06	2	105	2	11438569
Pubmed	GNAQ/GNA11 Mosaicism Is Associated with Abnormal Serum Calcium Indices and Microvascular Neurocalcification.	GNA11 GNAQ	9.03e-06	2	105	2	37802294
Pubmed	Mosaic Activating Mutations in GNA11 and GNAQ Are Associated with Phakomatosis Pigmentovascularis and Extensive Dermal Melanocytosis.	GNA11 GNAQ	9.03e-06	2	105	2	26778290
Pubmed	Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors.	GNA11 GNAQ	9.03e-06	2	105	2	26628681
Pubmed	Skeletal Muscle-Specific Activation of Gq Signaling Maintains Glucose Homeostasis.	GNA11 GNAQ	9.03e-06	2	105	2	30936140
Pubmed	The time-course of agonist-induced solubilization of trimeric G(q)alpha/G(11)alpha proteins resolved by two-dimensional electrophoresis.	GNA11 GNAQ	9.03e-06	2	105	2	17552882
Pubmed	Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins.	FLI1 ERG	9.03e-06	2	105	2	33275876
Pubmed	Patient survival in uveal melanoma is not affected by oncogenic mutations in GNAQ and GNA11.	GNA11 GNAQ	9.03e-06	2	105	2	23778528
Pubmed	High throughput mass spectrometry-based mutation profiling of primary uveal melanoma.	GNA11 GNAQ	9.03e-06	2	105	2	22977135
Pubmed	An experimental strategy to probe Gq contribution to signal transduction in living cells.	GNA11 GNAQ	9.03e-06	2	105	2	33639168
Pubmed	GNAQ and GNA11 mutant nonuveal melanoma: a subtype distinct from both cutaneous and uveal melanoma.	GNA11 GNAQ	9.03e-06	2	105	2	32064597
Pubmed	Mutational analysis of GNAQ and GNA11 to aid therapy management of a choroidal melanoma metastatic to the contralateral orbit.	GNA11 GNAQ	9.03e-06	2	105	2	23572068
Pubmed	Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations.	GNA11 GNAQ	9.03e-06	2	105	2	31173078
Pubmed	Low mutational burden of eight genes involved in the MAPK/ERK, PI3K/AKT, and GNAQ/11 pathways in female genital tract primary melanomas.	GNA11 GNAQ	9.03e-06	2	105	2	25695059
Pubmed	Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.	ITPR1 ITPR2	9.03e-06	2	105	2	19120126
Pubmed	Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.	GNA11 GNAQ	9.03e-06	2	105	2	29209985
Pubmed	ERG and FLI1 are useful immunohistochemical markers in phosphaturic mesenchymal tumors.	FLI1 ERG	9.03e-06	2	105	2	26122367
Pubmed	Group I metabotropic glutamate receptor signaling via Galpha q/Galpha 11 secures the induction of long-term potentiation in the hippocampal area CA1.	GNA11 GNAQ	9.03e-06	2	105	2	12351712
Pubmed	Dipeptidyl-peptidase 4 and attractin expression is increased in circulating blood monocytes of obese human subjects.	ATRN DPP4	9.03e-06	2	105	2	20198559
Pubmed	Cardiac remodeling in Gαq and Gα11 knockout mice.	GNA11 GNAQ	9.03e-06	2	105	2	26476043
Pubmed	Tumor-suppressive miRNA-135a inhibits breast cancer cell proliferation by targeting ELK1 and ELK3 oncogenes.	ELK1 ELK3	9.03e-06	2	105	2	29892795
Pubmed	GNA14 and GNAQ somatic mutations cause spinal and intracranial extra-axial cavernous hemangiomas.	GNA14 GNAQ	9.03e-06	2	105	2	38917801
Pubmed	Early-onset hypertension associated with extensive cutaneous capillary malformations harboring postzygotic variants in GNAQ and GNA11.	GNA11 GNAQ	9.03e-06	2	105	2	36440997
Pubmed	Loss of Gq/11 family G proteins in the nervous system causes pituitary somatotroph hypoplasia and dwarfism in mice.	GNA11 GNAQ	9.03e-06	2	105	2	15713647
Pubmed	Distinct roles of Galpha(q) and Galpha11 for Purkinje cell signaling and motor behavior.	GNA11 GNAQ	9.03e-06	2	105	2	15175381
Pubmed	GNAQ and GNA11 mutations in melanocytomas of the central nervous system.	GNA11 GNAQ	9.03e-06	2	105	2	22307269
Pubmed	Oncogenic GNAQ and GNA11 mutations in uveal melanoma in Chinese.	GNA11 GNAQ	9.03e-06	2	105	2	25280020
Pubmed	Function of PEA3 Ets transcription factors in mammary gland development and oncogenesis.	FLI1 ETV4 ELK3	9.50e-06	14	105	3	14635793
Pubmed	Mechanism of GTP hydrolysis by G-protein alpha subunits.	GNA14 GNA11 GNAQ	1.18e-05	15	105	3	7937899
Pubmed	Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1).	GNA14 GNA11 GNAQ	1.18e-05	15	105	3	11118617
Pubmed	Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.	PCDHA9 PCDHA13 PCDHA12	1.18e-05	15	105	3	15640798
Pubmed	Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.	PCDHA9 PCDHA13 PCDHA12	1.76e-05	17	105	3	29911975
Pubmed	CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.	PCDHA9 PCDHA13 PCDHA12	2.11e-05	18	105	3	15570159
Pubmed	TIF1gamma controls erythroid cell fate by regulating transcription elongation.	SSBP2 SUPT16H SSBP4	2.11e-05	18	105	3	20603019
Pubmed	Genomic organization of the family of CNR cadherin genes in mice and humans.	PCDHA9 PCDHA13 PCDHA12	2.11e-05	18	105	3	10662547
Cytoband	5q31	PCDHA9 PCDHA13 PCDHA12 PCDHGA8	1.47e-04	115	105	4	5q31
Cytoband	9q21	GNA14 GNAQ	2.81e-04	11	105	2	9q21
Cytoband	Ensembl 112 genes in cytogenetic band chr1q23	OLFML2B ETV3 SLAMF1 ETV3L	1.85e-03	226	105	4	chr1q23
Cytoband	1q25.1	CENPL ACBD6	2.77e-03	34	105	2	1q25.1
GeneFamily	ETS transcription factor family	FLI1 ERG ETV3 ETV4 ETV3L ELK1 ELK3	7.74e-12	28	67	7	534
GeneFamily	Inositol 1,4,5-triphosphate receptors\|Protein phosphatase 1 regulatory subunits	ITPR1 ITPR2	4.05e-05	3	67	2	297
GeneFamily	Clustered protocadherins	PCDHA9 PCDHA13 PCDHA12 PCDHGA8	9.26e-05	64	67	4	20
GeneFamily	Dyneins, axonemal	DNAH3 DNAH9	1.77e-03	17	67	2	536
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	FLI1 ERG ITPR1 ITPR2 GNA14 SLCO2A1 PCDH15 ELK3 DOCK6	7.14e-10	189	105	9	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FLI1 ERG SLC45A4 GNA14 SLCO2A1 MEDAG DOCK6	2.30e-07	179	105	7	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB4 ERBB4 NEXMIF STK32B ETV4 SSBP2 MYO3B	2.77e-07	184	105	7	d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB4 ERBB4 HS6ST2 STK32B ME3 ITPR1 MYO3B	3.32e-07	189	105	7	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ERG FRYL SLC45A4 GNA14 TJP1 SLCO2A1 DOCK6	3.44e-07	190	105	7	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	FLI1 ERG GNA14 SLCO2A1 ELK3 GNAQ ARHGEF3	3.44e-07	190	105	7	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP47 DNAH3 CHST9 ROPN1L GNA14 PLPP2 DNAH9	3.96e-07	194	105	7	958e648138676d46698090b4046cb484083ae449
ToppCell	facs-Lung-ENDOMUCIN-18m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERG GOLM2 TJP1 SLCO2A1 ELK3 GNAQ ARHGEF3	4.24e-07	196	105	7	f6df26ab9eebae893768a4f70a064ce9f60da93c
ToppCell	facs-Lung-ENDOMUCIN\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERG GOLM2 TJP1 SLCO2A1 ELK3 GNAQ ARHGEF3	4.24e-07	196	105	7	69f03546c42c942ab8ac8746167c8d44d574b4c6
ToppCell	facs-Lung-18m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLI1 ERG TJP1 SLCO2A1 ELK3 GNAQ ARHGEF3	4.70e-07	199	105	7	c11e0044d3cc37f6bb26df033ad4448b419addfc
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLI1 ERG RNF213 TJP1 ELK3 ARHGEF3 DOCK6	4.86e-07	200	105	7	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	Biopsy_Control_(H.)-Epithelial-Ciliated\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CFAP47 DNAH3 CHST9 ROPN1L PLPP2 AGBL2 DNAH9	4.86e-07	200	105	7	9ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLI1 ERG RNF213 MYO1B KBTBD2 PICALM ELK3	4.86e-07	200	105	7	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLI1 ERG RNF213 TJP1 ELK3 ARHGEF3 DOCK6	4.86e-07	200	105	7	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLI1 ERG RNF213 TJP1 ELK3 ARHGEF3 DOCK6	4.86e-07	200	105	7	a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCell	LPS_IL1RA_TNF-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLI1 ERG RNF213 TJP1 ELK3 ARHGEF3 DOCK6	4.86e-07	200	105	7	d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	CFAP47 DNAH3 DSP CHST9 ROPN1L DNAH9	1.58e-06	151	105	6	8216462e723fec2797387929dde095370947e10a
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Brinp3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	OLFML2B ETV4 ATP6AP1L ME3 SEPTIN7 ARHGAP8	2.47e-06	163	105	6	b0aa4a620bd58011225b42ea6dda04e3101ba342
ToppCell	pdx-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ATRN DPP4 CHST9 KLC4 ARHGEF3 KLB	3.84e-06	176	105	6	1e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 NEXMIF MYO1B SLC45A4 ITPR1 MYO3B	4.23e-06	179	105	6	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	CFAP47 DNAH3 CHST9 ROPN1L AGBL2 DNAH9	4.66e-06	182	105	6	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	CFAP47 DNAH3 CHST9 ROPN1L AGBL2 DNAH9	4.66e-06	182	105	6	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 HS6ST2 STK32B ITPR1 ITPR2 MYO3B	4.81e-06	183	105	6	31ab55d5f3639f5964541d5eae23044dbda3356e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 HS6ST2 STK32B ITPR1 TCAIM MYO3B	4.96e-06	184	105	6	e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ERG SLC45A4 GNA14 TJP1 SLCO2A1 DOCK6	4.96e-06	184	105	6	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	ERBB4 DSP HS6ST2 NEXMIF ROS1 ARHGAP8	5.12e-06	185	105	6	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IFT172 MYO1B ITPR2 PLPP2 TREH ARHGAP8	5.12e-06	185	105	6	686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 HS6ST2 STK32B ITPR1 ITPR2 MYO3B	5.12e-06	185	105	6	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	CFAP47 DNAH3 CHST9 ROPN1L AGBL2 DNAH9	5.12e-06	185	105	6	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	VPS13C RNF213 FRYL TUBGCP4 ITPR2 DOP1B	5.28e-06	186	105	6	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 HS6ST2 STK32B ITPR1 ITPR2 MYO3B	5.44e-06	187	105	6	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 ERG DDX60 RNF213 ELK3 ARHGEF3	5.44e-06	187	105	6	f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	FLI1 ERG GNA14 SLCO2A1 PCDH15 DOCK6	5.44e-06	187	105	6	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	CFAP47 DNAH3 CHST9 ROPN1L AGBL2 DNAH9	5.61e-06	188	105	6	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	ERG SLC45A4 GNA14 TJP1 SLCO2A1 DOCK6	5.61e-06	188	105	6	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 HS6ST2 STK32B ITPR1 TCAIM MYO3B	5.61e-06	188	105	6	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	ERBB4 HS6ST2 MYO1B ME3 ITPR1 ARHGEF3	5.61e-06	188	105	6	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DSP HS6ST2 CHST9 TMEM62 SLCO2A1 SORL1	5.78e-06	189	105	6	5d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP47 DNAH3 CHST9 ROPN1L PLPP2 DNAH9	5.78e-06	189	105	6	dc440015949a768188c67661b6be63b1ead1a0f0
ToppCell	Control-Epithelial-Ciliated\|Control / Disease state, Lineage and Cell class	CFAP47 DNAH3 CHST9 ROPN1L PLPP2 DNAH9	5.78e-06	189	105	6	c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB4 ERBB4 NEXMIF STK32B ETV4 SSBP2	5.78e-06	189	105	6	e059be2965cca70ff5576df055d0af1775b76e00
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FLI1 ERG ITPR2 GNA14 SLCO2A1 PCDH15	5.78e-06	189	105	6	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 HS6ST2 MYO1B ME3 ITPR1 ARHGEF3	5.78e-06	189	105	6	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	FLI1 ERG ITPR2 GNA14 SLCO2A1 PCDH15	5.78e-06	189	105	6	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 HS6ST2 MYO1B ME3 ITPR1 ARHGEF3	5.78e-06	189	105	6	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 DSP OLFML2B SSBP2 LRP1 MEDAG	5.78e-06	189	105	6	2a5fda73d38bdc23cf47e5335ffd4e086e990245
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	CFAP47 DNAH3 CHST9 ROPN1L AGBL2 DNAH9	5.78e-06	189	105	6	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 HS6ST2 STK32B ME3 ITPR1 MYO3B	5.96e-06	190	105	6	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	CFAP47 DNAH3 CHST9 ROPN1L PLPP2 DNAH9	6.14e-06	191	105	6	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 HS6ST2 STK32B ITPR1 TCAIM MYO3B	6.14e-06	191	105	6	963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	VPS13C RNF213 FRYL UBE4A EDRF1 DOP1B	6.14e-06	191	105	6	9454f642c3621370fa23640b631301346b300950
ToppCell	ASK428-Epithelial-Ciliated\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH3 CHST9 ROPN1L PLPP2 AGBL2 DNAH9	6.14e-06	191	105	6	0c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	FLI1 ERG GNA14 SLCO2A1 ELK3 DOCK6	6.14e-06	191	105	6	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	Control-Epithelial\|Control / Condition, Lineage and Cell class	CFAP47 DNAH3 CHST9 ROPN1L PLPP2 DNAH9	6.14e-06	191	105	6	6228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	FLI1 ERG ITPR2 GNA14 SLCO2A1 PCDH15	6.33e-06	192	105	6	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ERG GNA14 SLCO2A1 ELK3 ARHGEF3 DOCK6	6.33e-06	192	105	6	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	LPS-IL1RA+antiTNF-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 ERG TJP1 ELK3 ARHGEF3 DOCK6	6.33e-06	192	105	6	04f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 ERG TJP1 ELK3 ARHGEF3 DOCK6	6.33e-06	192	105	6	c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	FLI1 ERG GNA14 SLCO2A1 ELK3 DOCK6	6.33e-06	192	105	6	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	COPD-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP47 DNAH3 CHST9 ROPN1L GNA14 DNAH9	6.33e-06	192	105	6	eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 ERG TJP1 ELK3 ARHGEF3 DOCK6	6.52e-06	193	105	6	e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	FLI1 ERG GNA14 SLCO2A1 PCDH15 GNAQ	6.52e-06	193	105	6	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	LPS-antiTNF-Endothelial-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 ERG TJP1 ELK3 ARHGEF3 DOCK6	6.52e-06	193	105	6	02f633b016ab19bfa65bfd0cf32f000549a62148
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 ERG TJP1 ELK3 ARHGEF3 DOCK6	6.52e-06	193	105	6	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	LPS-antiTNF-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 ERG TJP1 ELK3 ARHGEF3 DOCK6	6.52e-06	193	105	6	5122b1ffba42de190061be34ecdc6176f84e56a3
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLI1 ERG TFPI2 SLCO2A1 ELK3 ARHGEF3	6.52e-06	193	105	6	0f2967afbbf4e538b63f985c0acc2e5d9aab7589
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ERG GNA14 SLCO2A1 MEDAG ELK3	6.52e-06	193	105	6	1f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ERG GNA14 SLCO2A1 ELK3 DOCK6	6.72e-06	194	105	6	f76808666fb875fc787751cbfd924d9be20a8192
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 ERG TJP1 ELK3 ARHGEF3 DOCK6	6.72e-06	194	105	6	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 ERG TJP1 ELK3 ARHGEF3 DOCK6	6.72e-06	194	105	6	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	wk_15-18-Epithelial-Proximal_epithelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CFAP47 DNAH3 CHST9 ROPN1L PLPP2 DNAH9	6.72e-06	194	105	6	b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 ERBB4 DSP CHST9 PLPP2 MYO3B	6.72e-06	194	105	6	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ERG GNA14 SLCO2A1 ELK3 DOCK6	6.72e-06	194	105	6	f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ERG GNA14 SLCO2A1 ELK3 DOCK6	6.72e-06	194	105	6	a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	CFAP47 DNAH3 ERBB4 ROPN1L GNA14 DNAH9	6.92e-06	195	105	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Ciliated\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CFAP47 DNAH3 CHST9 ROPN1L PLPP2 DNAH9	6.92e-06	195	105	6	cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERG GOLM2 TJP1 SLCO2A1 ELK3 GNAQ	6.92e-06	195	105	6	52b2bbf12e5f86c493f6634697aeb23a68cc916d
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERG GOLM2 TJP1 SLCO2A1 ELK3 GNAQ	6.92e-06	195	105	6	e5f14f6015ea5e6fa065f906ad22157e3de15c68
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERG GOLM2 TJP1 SLCO2A1 ELK3 GNAQ	6.92e-06	195	105	6	5b84fd5be31386eb1d6048bbf28626032361842e
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	CFAP47 DNAH3 ERBB4 ROPN1L GNA14 DNAH9	6.92e-06	195	105	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATRN HS6ST2 MYO1B ME3 ITPR1 MYO3B	6.92e-06	195	105	6	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ERG GNA14 SLCO2A1 ELK3 DOCK6	7.12e-06	196	105	6	8ad8efb631164b46f0c082572270188e5ead20bf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ERG GNA14 SLCO2A1 ELK3 DOCK6	7.12e-06	196	105	6	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSP IFT172 OLFM4 ETV4 PLPP2 ARHGAP8	7.12e-06	196	105	6	97324c9e93f833e1f218e81fb53066d44c6892df
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ERG GNA14 SLCO2A1 ELK3 DOCK6	7.12e-06	196	105	6	9606ea7e42f707e69ea891b3521037613b9675f5
ToppCell	COVID-19-kidney-VWF+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	FLI1 ERG GNA14 SLCO2A1 ELK3 DOCK6	7.12e-06	196	105	6	b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	CFAP47 DNAH3 ERBB4 GNA14 PLPP2 DNAH9	7.12e-06	196	105	6	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	COVID-19-lung-Capillary_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FLI1 ERG GNA14 SLCO2A1 PCDH15 DOCK6	7.12e-06	196	105	6	ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ERG PICALM GNA14 MEDAG ELK3	7.12e-06	196	105	6	e224338490691d92c1f70b57112fabdcc92b06a9
ToppCell	AT2_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	DPP4 DSP HS6ST2 MYO1B SLCO2A1 ROS1	7.33e-06	197	105	6	5e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH3 IFT172 CHST9 ROPN1L DNAH9	7.33e-06	197	105	6	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ERG GNA14 SLCO2A1 ELK3 DOCK6	7.33e-06	197	105	6	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH3 IFT172 CHST9 ROPN1L DNAH9	7.33e-06	197	105	6	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ERG GNA14 SLCO2A1 ELK3 DOCK6	7.33e-06	197	105	6	0f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell	COVID-19-lung-Capillary_1\|lung / Disease (COVID-19 only), tissue and cell type	FLI1 ERG GNA14 SLCO2A1 PCDH15 DOCK6	7.33e-06	197	105	6	7e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH3 IFT172 CHST9 ROPN1L DNAH9	7.33e-06	197	105	6	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH3 IFT172 CHST9 ROPN1L DNAH9	7.33e-06	197	105	6	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	wk_20-22-Epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DSP CHST9 ROPN1L PLPP2 DNAH9	7.33e-06	197	105	6	468071c1911cdf8e8806a78dbceb95379e28ae91
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ERG GNA14 SLCO2A1 ELK3 DOCK6	7.33e-06	197	105	6	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLI1 ERG MYO1B SLCO2A1 ELK3 DOCK6	7.33e-06	197	105	6	b18f2c14d6720f6ae8520c0800356f4a57393ad3
Drug	Flutamide [13311-84-7]; Up 200; 14.4uM; PC3; HT_HG-U133A	MYO1B SSBP2 LRP1 NUP188 SEPTIN7 DOCK6 EDRF1 PURG	4.00e-06	199	105	8	4539_UP
Disease	Malignant melanoma of iris	SF3B1 GNA11 GNAQ	4.11e-07	5	103	3	C0346373
Disease	Malignant melanoma of choroid	SF3B1 GNA11 GNAQ	4.11e-07	5	103	3	C0346388
Disease	Uveal melanoma	SF3B1 GNA11 GNAQ	2.28e-06	8	103	3	C0220633
Disease	Ewings sarcoma	FLI1 ERG ETV4	2.28e-06	8	103	3	C0553580
Disease	obesity (implicated_via_orthology)	SEC16B ETV4 ITPR1 ITPR2 GNA14 GNA11 GNAQ	1.08e-05	215	103	7	DOID:9970 (implicated_via_orthology)
Disease	Hypoxic Brain Damage	ITPR1 ITPR2	1.21e-05	2	103	2	C1140716
Disease	Anoxic Encephalopathy	ITPR1 ITPR2	1.21e-05	2	103	2	C0003132
Disease	Brain Hypoxia	ITPR1 ITPR2	1.21e-05	2	103	2	C1527348
Disease	Phakomatosis cesioflammea	GNA11 GNAQ	1.21e-05	2	103	2	C3838883
Disease	Anoxia of brain	ITPR1 ITPR2	1.21e-05	2	103	2	C0995195
Disease	Congenital hemangioma	GNA11 GNAQ	1.21e-05	2	103	2	C0235753
Disease	Port-wine stain with oculocutaneous melanosis	GNA11 GNAQ	1.21e-05	2	103	2	C1274879
Disease	Extra-osseous Ewing's sarcoma	FLI1 ERG	7.21e-05	4	103	2	C0279980
Disease	neutrophil count	EYA4 PCDHA9 ERG OLFML2B ETV3 PCDHA13 PCDHA12 MYO1B SLAMF1 SLC45A4 ITPR2 POLI SSBP4 AGBL2 DOCK6	8.98e-05	1382	103	15	EFO_0004833
Disease	Hypoplastic Left Heart Syndrome	PCDHA9 PCDHA13	1.20e-04	5	103	2	C0152101
Disease	1,5 anhydroglucitol measurement	PCDHA9 PCDHA13 PCDHA12	1.41e-04	29	103	3	EFO_0008009
Disease	multiple sclerosis	FLI1 ERG ETV3 SLAMF1 ETV3L ITPR1 IL22RA2 ARHGEF3 AGBL2	2.39e-04	594	103	9	MONDO_0005301
Disease	melanoma	ERBB4 TFPI2 MYO1B GNA11 ROS1 GNAQ	2.40e-04	248	103	6	C0025202
Disease	visceral adipose tissue measurement	SEC16B ERBB4 SSBP2 PHF2 MYO3B ARHGEF3 AGBL2 PURG	2.89e-04	481	103	8	EFO_0004765
Disease	N-acetylneuraminate measurement	SLC45A4 ARHGEF3	3.33e-04	8	103	2	EFO_0020022
Disease	Malignant neoplasm of breast	GPC1 ERBB4 TFPI2 ETV4 TRMT11 PFKFB4 SLAMF1 ATP6AP1L ELK3 DNAH9 PURG SORL1	3.70e-04	1074	103	12	C0006142
Disease	Cutaneous Melanoma	ERBB4 GNA11 GNAQ	4.00e-04	41	103	3	C0151779
Disease	Mental deterioration	PICALM SORL1	4.28e-04	9	103	2	C0234985
Disease	Mild cognitive disorder	PICALM SORL1	4.28e-04	9	103	2	C1270972
Disease	susceptibility to urinary tract infection measurement	SEC16B ERBB4 GOLM2 TUBGCP4	5.68e-04	108	103	4	EFO_0008413
Disease	trimethyllysine measurement	IL22RA2 GNAQ	6.50e-04	11	103	2	EFO_0009134
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ITPR1 ITPR2	7.78e-04	12	103	2	DOID:1441 (implicated_via_orthology)
Disease	Colorectal Carcinoma	DNAH3 EYA4 TFPI2 MYO1B ADAM29 SLCO2A1 LRP1 EDRF1 SORL1	7.98e-04	702	103	9	C0009402
Disease	breast carcinoma	SEC16B ERBB4 ADAM29 CHST9 SSBP2 PFKFB4 ATP6AP1L ITPR1 ROPN1L GNAQ SSBP4	8.70e-04	1019	103	11	EFO_0000305
Disease	hypoxanthine mesurement	FUT10 ERBB4	1.07e-03	14	103	2	EFO_0010500
Disease	trimethylamine-N-oxide measurement	ITPR2 UBE3C	1.07e-03	14	103	2	EFO_0010541
Disease	Impaired cognition	PICALM SORL1	1.07e-03	14	103	2	C0338656
Disease	neutrophil count, basophil count	PCDHA9 PCDHA13 PCDHA12 SLC45A4 SSBP4	1.15e-03	224	103	5	EFO_0004833, EFO_0005090
Disease	B-cell acute lymphoblastic leukemia	ERG ELK3	1.23e-03	15	103	2	EFO_0000094
Disease	Alzheimer disease, gastroesophageal reflux disease	EYA4 ERG PICALM SSBP4 SORL1	1.25e-03	228	103	5	EFO_0003948, MONDO_0004975
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	TLR6 TJP1	1.59e-03	17	103	2	DOID:8677 (biomarker_via_orthology)
Disease	mean arterial pressure	ERG RNF213 SIK1 ASB15 ROPN1L GNA11 ARHGEF3	1.86e-03	499	103	7	EFO_0006340
Disease	hippocampal tail volume	DPP4 ATP6AP1L	1.99e-03	19	103	2	EFO_0009398

Protein segments in the cluster

Peptide	Gene	Start	Entry
LDSIKNYYRKYSAVR	TMEM62	151	Q0P6H9
IDNYLYIRYERNDSK	ADAM29	206	Q9UKF5
YEDRYALAIFLNYRK	ERBB4	111	Q15303
NYDKLSRALRYYYDK	ELK1	56	P19419
RYYKERLLYLEEGQK	ARHGEF3	311	Q9NR81
NYDKLSRALRYYYDK	ERG	361	P11308
NYDKLSRALRYYYNK	ETV3	86	P41162
RYILFKEYDLYGQEL	ASB15	571	Q8WXK1
KQYEAARLEYDAYRT	ARFIP2	226	P53365
LKYLLLTYYDANKRD	ANKRD36B	36	Q8N2N9
SREQLLYLYARYKQV	ACBD6	61	Q9BR61
NYDKLSRSLRYYYEK	ETV4	391	P43268
DYDLKYCYVDRNKRT	RAVER2	91	Q9HCJ3
YKNYYSLVLDRALDR	PCDHA9	401	Q9Y5H5
YYRLVTRKYLDRENV	PCDHGA8	401	Q9Y5G5
DRRREYQLSDSTKYY	GNAQ	146	P50148
KADLEVLTYYRYQLN	ITPR2	721	Q14571
GKYEAVERYYQRALA	KLC4	351	Q9NSK0
YLLKNYDRFHYLLDN	MGAT3	486	Q09327
EDRDVLSYYRYQLNL	ITPR1	726	Q14643
FRDLYSELRLYYRGA	GPC1	141	P35052
YNKAIDYYLKALRSL	EDRF1	936	Q3B7T1
RYYLRKLNLDGSNYT	LRP1	3036	Q07954
NKYRLADDLYRYDVD	ATRN	526	O75882
DYRYRSYSSVIEKAL	DOP1B	11	Q9Y3R5
SYKVRLVLYGERYND	DDX60	971	Q8IY21
YLYLDKIYCLLSVRN	EFCAB9	11	A8MZ26
LEFALRDQDKYRYRY	PFKFB4	346	Q16877
LESDYEYEYLLALRL	FRYL	2011	O94915
RAKYVTYQYDLELDR	KBTBD2	546	Q8IY47
TDYLKNTYRLKLYSL	DPP4	46	P27487
DLAQLLLRLDYNKYY	TUBGCP4	641	Q9UGJ1
KNVSIEDYYELLYRV	IL22RA2	191	Q969J5
AGEAYLVYTDRLYSR	PLPP2	71	O43688
YKRYRVRSYEAVAAA	RBM4B	221	Q9BQ04
RLSSYIKRYVELTNY	MEDAG	86	Q5VYS4
YILDLQDRNTASKYY	IFT172	901	Q9UG01
YKNYYSLVLDSALDR	PCDHA13	401	Q9Y5I0
IYTAVKLNREVRDYY	PCDH15	771	Q96QU1
LAFRYRRVKELYNTY	EYA4	481	O95677
TYELKDRVTYFDRNY	DOCK6	1831	Q96HP0
YKFSYSNLKEYSRLL	CENPL	81	Q8N0S6
LERYYYYLTNGIRKD	DNAH3	231	Q8TD57
YIRRLDSDDRLYEAY	FUT10	336	Q6P4F1
ARYIELLTRSGDYYR	DSP	1001	P15924
DRRREYQLSDSAKYY	GNA11	146	P29992
NYDKLSRALRYYYDK	FLI1	331	Q01543
YEYELTLRTDLYTNK	AGBL2	286	Q5U5Z8
YDKLSRALRYYYDKN	ELK3	56	P41970
YYERQQSDLDKYIIL	ME3	96	Q16798
ALEDDRLRKYYLGKY	KLB	896	Q86Z14
ELYSYAKDLFLQRYQ	HS6ST2	486	Q96MM7
LGRRQNDSLDKYYYA	LAMB4	241	A4D0S4
KSRYEDLKYIYNQLR	DNAH9	256	Q9NYC9
YDKLSRALRYYYNKR	ETV3L	91	Q6ZN32
DRTYKLSCRILYQYL	CGRRF1	201	Q99675
YSYYLDNRLKDERIS	POLI	621	Q9UNA4
ILLKSRYDVRAYYVE	CFAP47	2296	Q6ZTR5
LYLSERYAELYRRQQ	IER5L	46	Q5T953
YKNYYSLVLDSALDR	PCDHA12	401	Q9UN75
LKTDYIERDNRKYYL	PURG	171	Q9UJV8
DYRKNNTYLVKRLEY	GOLM2	146	Q6P4E1
YDRRREYQLSDSAKY	GNA14	141	O95837
RNLLYEYAREGYSAL	SARS2	41	Q9NP81
RYSEFELLRSYLLVY	SNX4	106	O95219
SQAREKLALYVYEYL	SSBP2	16	P81877
ILYAVRKSIYRYDLA	SORL1	761	Q92673
RANLRQYGLEKYYLD	TRMT11	271	Q7Z4G4
YYSLLDVFYNRLLKS	TCAIM	341	Q8N3R3
EFVDYYYSTNRKRVL	PHF2	176	O75151
RAKRKVRYSEDYLYD	NEXMIF	481	Q5QGS0
YLGDRYKFYLENLTL	SLAMF1	91	Q13291
AIYYLLLERLKEYRN	SIK1B	336	A0A0B4J2F2
AIYYLLLERLKEYRN	SIK1	336	P57059
YYNRAFTRNIIKYDL	OLFML2B	576	Q68BL8
DKDAYYRRVKRLYSN	SUPT16H	6	Q9Y5B9
DGRLLEYYRLYNTLD	OLFM4	296	Q6UX06
EYYRLYNTLDDLLLY	OLFM4	301	Q6UX06
SRLYARYFQGDLKLY	PDK3	331	Q15120
DLTRTERQLIYDFYY	CHST9	416	Q7L1S5
RYSRYLNEKAVSYRQ	PICALM	126	Q13492
KYLDNYDLSVRVIYV	SLC45A4	581	Q5BKX6
YYDNDALRDRYLGLQ	SLCO2A1	596	Q92959
LRARRLYQLAYDTYQ	GH2	41	P01242
RYLVYGDEYKALRDA	RNF213	4326	Q63HN8
KTFSYVYRYLARLDS	ROPN1L	166	Q96C74
YENYRSRKLAAVTYN	SEPTIN7	306	Q16181
RIYNDDKNTYIRYEL	SF3B1	1286	O75533
QAREKLALYVYEYLL	SSBP4	16	Q9BWG4
LKYLEDNRILTYQYG	TREH	436	O43280
RQSQALILKIADYYY	NUP188	116	Q5SRE5
DDLIFKLAYYEIRYQ	VPS13C	3376	Q709C8
ARDIYKNDYYRKRGE	ROS1	2106	P08922
IYGERLYETSYRLSK	GTF3C4	211	Q9UKN8
FQVYKLLYASRLADY	SEC16B	626	Q96JE7
LSYILLDLRNYYIKE	TLR6	171	Q9Y2C9
HQRLLEYLKYTLDQY	ARHGAP8	51	P85298
DEEYYRKQLSYFDRR	TJP1	1351	Q07157
YICELALALEYLQRY	STK32B	126	Q9NY57
RALLLRYYYDRYTQS	TFPI2	46	P48307
YAYLDILLYFTRQKD	UBE4A	291	Q14139
AYDLARRAIYQATYR	PSMB5	211	P28074
IYLRYLDQQYDLIAS	ATP6AP1L	171	Q52LC2
KELYLIRYNNYDRAV	TMLHE	326	Q9NVH6
TIRRNYIYEDAYDKL	UBE3C	726	Q15386
YYARDALAKNLYSRL	MYO1B	346	O43795
HQLQKRYADLLIYTY	MYO3B	361	Q8WXR4