| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | SUMO-modified protein reader activity | 8.58e-06 | 2 | 59 | 2 | GO:0140037 | |
| GeneOntologyMolecularFunction | cobalt ion binding | 2.38e-04 | 8 | 59 | 2 | GO:0050897 | |
| GeneOntologyMolecularFunction | complement component C3b binding | 5.56e-04 | 12 | 59 | 2 | GO:0001851 | |
| Domain | VWF_dom | 2.99e-04 | 42 | 58 | 3 | IPR001007 | |
| Domain | TIL | 6.13e-04 | 12 | 58 | 2 | PF01826 | |
| Domain | C8 | 6.13e-04 | 12 | 58 | 2 | PF08742 | |
| Domain | Unchr_dom_Cys-rich | 7.23e-04 | 13 | 58 | 2 | IPR014853 | |
| Domain | C8 | 7.23e-04 | 13 | 58 | 2 | SM00832 | |
| Domain | TIL_dom | 8.42e-04 | 14 | 58 | 2 | IPR002919 | |
| Domain | VWD | 1.11e-03 | 16 | 58 | 2 | SM00216 | |
| Domain | VWF_type-D | 1.11e-03 | 16 | 58 | 2 | IPR001846 | |
| Domain | VWFD | 1.11e-03 | 16 | 58 | 2 | PS51233 | |
| Domain | VWD | 1.11e-03 | 16 | 58 | 2 | PF00094 | |
| Domain | VWC_out | 1.57e-03 | 19 | 58 | 2 | SM00215 | |
| Domain | CT | 2.10e-03 | 22 | 58 | 2 | SM00041 | |
| Domain | Cys_knot_C | 2.72e-03 | 25 | 58 | 2 | IPR006207 | |
| Domain | CTCK_2 | 2.72e-03 | 25 | 58 | 2 | PS01225 | |
| Domain | VWC | 3.40e-03 | 28 | 58 | 2 | PF00093 | |
| Domain | FHA | 4.16e-03 | 31 | 58 | 2 | PF00498 | |
| Domain | TYR_PHOSPHATASE_DUAL | 4.99e-03 | 34 | 58 | 2 | PS50054 | |
| Domain | TYR_PHOSPHATASE_DUAL_dom | 5.28e-03 | 35 | 58 | 2 | IPR020422 | |
| Domain | DSPc | 5.28e-03 | 35 | 58 | 2 | SM00195 | |
| Domain | FHA_dom | 5.58e-03 | 36 | 58 | 2 | IPR000253 | |
| Domain | VWFC_1 | 5.58e-03 | 36 | 58 | 2 | PS01208 | |
| Domain | - | 5.58e-03 | 36 | 58 | 2 | 2.60.200.20 | |
| Domain | VWC | 6.20e-03 | 38 | 58 | 2 | SM00214 | |
| Domain | VWFC_2 | 6.20e-03 | 38 | 58 | 2 | PS50184 | |
| Domain | Dual-sp_phosphatase_cat-dom | 7.19e-03 | 41 | 58 | 2 | IPR000340 | |
| Domain | DSPc | 7.19e-03 | 41 | 58 | 2 | PF00782 | |
| Domain | Sushi | 1.14e-02 | 52 | 58 | 2 | PF00084 | |
| Domain | SMAD_FHA_domain | 1.14e-02 | 52 | 58 | 2 | IPR008984 | |
| Pubmed | 3.92e-07 | 87 | 59 | 5 | 12465718 | ||
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 32636836 | ||
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 21832009 | ||
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 10525530 | ||
| Pubmed | Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis. | 2.83e-06 | 2 | 59 | 2 | 10684855 | |
| Pubmed | Molecular cloning of a human serum protein structurally related to complement factor H. | 2.83e-06 | 2 | 59 | 2 | 1711047 | |
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 17942542 | ||
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 33651882 | ||
| Pubmed | A sumoylation site in PML/RARA is essential for leukemic transformation. | 2.83e-06 | 2 | 59 | 2 | 15710327 | |
| Pubmed | PML/TRIM19-Dependent Inhibition of Retroviral Reverse-Transcription by Daxx. | 2.83e-06 | 2 | 59 | 2 | 26566030 | |
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 18480450 | ||
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 15252119 | ||
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 15350595 | ||
| Pubmed | Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner. | 8.48e-06 | 3 | 59 | 2 | 31879127 | |
| Pubmed | Regulation of Pax3 transcriptional activity by SUMO-1-modified PML. | 8.48e-06 | 3 | 59 | 2 | 11244500 | |
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 23221561 | ||
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 11971979 | ||
| Pubmed | ST5 Positively Regulates Osteoclastogenesis via Src/Syk/calcium Signaling Pathways. | 8.48e-06 | 3 | 59 | 2 | 31707778 | |
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 26057166 | ||
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 31273197 | ||
| Pubmed | A novel hierarchical prognostic model of AML solely based on molecular mutations. | 8.48e-06 | 3 | 59 | 2 | 22915647 | |
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 12595526 | ||
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 15116119 | ||
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 26468536 | ||
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 20097304 | ||
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 28341773 | ||
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 30060604 | ||
| Pubmed | Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres. | 8.48e-06 | 3 | 59 | 2 | 28358373 | |
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 25497731 | ||
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 30292834 | ||
| Pubmed | Daxx-beta and Daxx-gamma, two novel splice variants of the transcriptional co-repressor Daxx. | 8.48e-06 | 3 | 59 | 2 | 21482821 | |
| Pubmed | C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation. | 8.48e-06 | 3 | 59 | 2 | 23728178 | |
| Pubmed | 8.48e-06 | 3 | 59 | 2 | 17419608 | ||
| Pubmed | A central chaperone-like role for 14-3-3 proteins in human cells. | 1.39e-05 | 861 | 59 | 9 | 36931259 | |
| Pubmed | 1.69e-05 | 4 | 59 | 2 | 24333077 | ||
| Pubmed | 1.69e-05 | 4 | 59 | 2 | 28851805 | ||
| Pubmed | 1.69e-05 | 4 | 59 | 2 | 12150977 | ||
| Pubmed | Coactivator-mediated estrogen response in human squamous cell carcinoma lines. | 1.69e-05 | 4 | 59 | 2 | 17400812 | |
| Pubmed | 1.69e-05 | 4 | 59 | 2 | 2115127 | ||
| Pubmed | Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs). | 1.69e-05 | 4 | 59 | 2 | 10545115 | |
| Pubmed | Daxx silencing sensitizes cells to multiple apoptotic pathways. | 1.69e-05 | 4 | 59 | 2 | 14517282 | |
| Pubmed | 1.69e-05 | 4 | 59 | 2 | 11948183 | ||
| Pubmed | 1.69e-05 | 4 | 59 | 2 | 17360386 | ||
| Pubmed | 1.69e-05 | 4 | 59 | 2 | 14985366 | ||
| Pubmed | Complement factor H and related proteins: an expanding family of complement-regulatory proteins? | 2.82e-05 | 5 | 59 | 2 | 8172644 | |
| Pubmed | Factor H-related proteins determine complement-activating surfaces. | 2.82e-05 | 5 | 59 | 2 | 25979655 | |
| Pubmed | Identification and sequence analysis of four complement factor H-related transcripts in mouse liver. | 2.82e-05 | 5 | 59 | 2 | 1689298 | |
| Pubmed | Sequestration and inhibition of Daxx-mediated transcriptional repression by PML. | 2.82e-05 | 5 | 59 | 2 | 10669754 | |
| Pubmed | ZIP kinase triggers apoptosis from nuclear PML oncogenic domains. | 2.82e-05 | 5 | 59 | 2 | 12917339 | |
| Pubmed | Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation. | 2.82e-05 | 5 | 59 | 2 | 10882117 | |
| Pubmed | A radiation hybrid map of complement factor H and factor H-related genes. | 2.82e-05 | 5 | 59 | 2 | 10380701 | |
| Pubmed | DAXX-dependent supply of soluble (H3.3-H4) dimers to PML bodies pending deposition into chromatin. | 4.23e-05 | 6 | 59 | 2 | 23222847 | |
| Pubmed | Dimerization of complement factor H-related proteins modulates complement activation in vivo. | 4.23e-05 | 6 | 59 | 2 | 23487775 | |
| Pubmed | 4.23e-05 | 6 | 59 | 2 | 27196323 | ||
| Pubmed | 4.23e-05 | 6 | 59 | 2 | 21474068 | ||
| Pubmed | 4.23e-05 | 6 | 59 | 2 | 12529400 | ||
| Pubmed | 4.23e-05 | 6 | 59 | 2 | 17438673 | ||
| Pubmed | 5.91e-05 | 7 | 59 | 2 | 16606617 | ||
| Pubmed | 5.91e-05 | 7 | 59 | 2 | 17081986 | ||
| Pubmed | 5.91e-05 | 7 | 59 | 2 | 15788656 | ||
| Pubmed | SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes. | 5.91e-05 | 7 | 59 | 2 | 21779164 | |
| Pubmed | Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations. | 6.21e-05 | 125 | 59 | 4 | 32891193 | |
| Pubmed | 7.87e-05 | 8 | 59 | 2 | 20972456 | ||
| Pubmed | Role of PML and PML-RARalpha in Mad-mediated transcriptional repression. | 7.87e-05 | 8 | 59 | 2 | 11430826 | |
| Pubmed | SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies. | 7.87e-05 | 8 | 59 | 2 | 27211601 | |
| Pubmed | 1.01e-04 | 9 | 59 | 2 | 18296443 | ||
| Pubmed | 1.01e-04 | 9 | 59 | 2 | 20059470 | ||
| Pubmed | Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins. | 1.01e-04 | 9 | 59 | 2 | 24637324 | |
| Pubmed | 1.26e-04 | 10 | 59 | 2 | 9373037 | ||
| Pubmed | 1.26e-04 | 10 | 59 | 2 | 18691969 | ||
| Pubmed | Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells. | 1.26e-04 | 10 | 59 | 2 | 24051437 | |
| Pubmed | 1.26e-04 | 10 | 59 | 2 | 15001550 | ||
| Pubmed | 1.26e-04 | 10 | 59 | 2 | 21840486 | ||
| Pubmed | Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. | 1.54e-04 | 11 | 59 | 2 | 38616920 | |
| Pubmed | 1.74e-04 | 486 | 59 | 6 | 20936779 | ||
| Pubmed | Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia. | 2.18e-04 | 13 | 59 | 2 | 35263589 | |
| Pubmed | Mapping of the syndecan genes in the mouse: linkage with members of the myc gene family. | 2.18e-04 | 13 | 59 | 2 | 7959737 | |
| Pubmed | Sequence and expression of murine type I hair keratins mHa2 and mHa3. | 2.54e-04 | 14 | 59 | 2 | 7514534 | |
| Pubmed | 2.54e-04 | 14 | 59 | 2 | 16452088 | ||
| Pubmed | Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer. | 2.75e-04 | 184 | 59 | 4 | 32908313 | |
| Pubmed | 2.93e-04 | 15 | 59 | 2 | 36305765 | ||
| Pubmed | 2.93e-04 | 15 | 59 | 2 | 10087197 | ||
| Pubmed | YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. | 4.25e-04 | 18 | 59 | 2 | 29249464 | |
| Pubmed | 4.75e-04 | 19 | 59 | 2 | 20660734 | ||
| Pubmed | Daxx Inhibits HIV-1 Reverse Transcription and Uncoating in a SUMO-Dependent Manner. | 4.75e-04 | 19 | 59 | 2 | 32545337 | |
| Pubmed | New genetic associations detected in a host response study to hepatitis B vaccine. | 4.78e-04 | 824 | 59 | 7 | 20237496 | |
| Pubmed | Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability. | 4.80e-04 | 588 | 59 | 6 | 38580884 | |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | 5.34e-04 | 1105 | 59 | 8 | 35748872 | |
| Pubmed | TRIM E3 ligases interfere with early and late stages of the retroviral life cycle. | 5.82e-04 | 21 | 59 | 2 | 18248090 | |
| Pubmed | 6.38e-04 | 407 | 59 | 5 | 12693553 | ||
| Pubmed | 6.69e-04 | 233 | 59 | 4 | 29518331 | ||
| Pubmed | Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. | CFAP20DC PHLDB1 ERV3-1 POLG SRC KIAA1328 CDC14B DENND2B CLBA1 | 8.59e-04 | 1489 | 59 | 9 | 28611215 |
| Pubmed | Identification of proximal SUMO-dependent interactors using SUMO-ID. | 9.42e-04 | 444 | 59 | 5 | 34795231 | |
| Pubmed | Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. | 1.04e-03 | 28 | 59 | 2 | 18587394 | |
| Pubmed | 1.27e-03 | 31 | 59 | 2 | 26618355 | ||
| Pubmed | Multiple genes encoding zinc finger domains are expressed in human T cells. | 1.27e-03 | 31 | 59 | 2 | 2288909 | |
| Pubmed | TBX1 is required for normal stria vascularis and semicircular canal development. | 1.27e-03 | 31 | 59 | 2 | 31550482 | |
| Pubmed | 1.27e-03 | 31 | 59 | 2 | 21441570 | ||
| Pubmed | 1.27e-03 | 31 | 59 | 2 | 21072187 | ||
| Pubmed | 1.36e-03 | 32 | 59 | 2 | 30532072 | ||
| Disease | C3 glomerulopathy | 1.26e-04 | 9 | 56 | 2 | C4087273 | |
| Disease | myelodysplastic syndrome (implicated_via_orthology) | 3.66e-04 | 15 | 56 | 2 | DOID:0050908 (implicated_via_orthology) | |
| Disease | ulcerative colitis | 4.35e-04 | 335 | 56 | 5 | EFO_0000729 | |
| Disease | Glioblastoma | 4.62e-04 | 79 | 56 | 3 | C0017636 | |
| Disease | SLAM family member 7 measurement | 4.72e-04 | 17 | 56 | 2 | EFO_0008287 | |
| Disease | glycerol measurement | 1.12e-03 | 26 | 56 | 2 | EFO_0010115 | |
| Disease | complement factor H-related protein 2 measurement | 1.39e-03 | 29 | 56 | 2 | EFO_0600055 | |
| Disease | Age related macular degeneration | 1.49e-03 | 30 | 56 | 2 | C0242383 | |
| Disease | Unipolar Depression | 1.49e-03 | 259 | 56 | 4 | C0041696 | |
| Disease | Complement deficiency disease | 1.80e-03 | 33 | 56 | 2 | C0272242 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| IPLEPDCKTSTCNSV | 186 | Q14264 | |
| PCSRRCSSTSPGVKK | 16 | O60729 | |
| KRDVPCDNVSSCPSS | 361 | P28799 | |
| SAIEGLSSTRPCCSK | 551 | P51828 | |
| CTTLTSKPCSRAITP | 226 | Q96MC9 | |
| CPSVVPSPCSSEKTF | 206 | P78524 | |
| RPGTCKTSVATQCDP | 716 | Q9UER7 | |
| PSTPGKCTSDLQRTQ | 681 | Q8IXJ9 | |
| TPGSTGKRVSTCPFC | 866 | Q6IQ32 | |
| TASCPTPKVQSRCSS | 281 | Q9NQX3 | |
| CSSSPSLPRSCKEIK | 31 | Q8WWA0 | |
| SSCSFETCPRPTEKQ | 501 | Q6WCQ1 | |
| SLTETLCPPKGRQTS | 116 | Q7Z3D4 | |
| SGSCPPTKFQCRTSG | 51 | Q9NPF0 | |
| KSCPRPASVCSSGVN | 16 | Q14532 | |
| SQGLPKTICPLCNTT | 581 | Q9Y6V0 | |
| TPPKCRSTISAEKCG | 136 | P36980 | |
| PSSISCAQTPCIPKE | 1006 | Q14005 | |
| SSCPVTNEIKPPSCL | 631 | Q5W0B1 | |
| TSDIPRTPVLGCCIS | 1066 | P54098 | |
| LCCETPKGCPVTSTS | 3616 | P98088 | |
| DGSSPSCVPRLCSLT | 31 | Q86VP3 | |
| KIPSETTTCNCESPG | 261 | Q86T90 | |
| TTTCNCESPGRKPAV | 266 | Q86T90 | |
| TPKQCQPSDTVCASV | 41 | O94772 | |
| QSAPESSCPCRGSVK | 191 | Q8IZJ4 | |
| SSCPCRGSVKNQPSE | 196 | Q8IZJ4 | |
| GSPLTERKVSIPSCC | 1651 | Q4AC94 | |
| CEGKSTLVPTCISQP | 136 | Q9BY84 | |
| KPVCFVPTCSESSPS | 111 | P60014 | |
| TLPATQCPDGKSVTC | 71 | P01877 | |
| TPQQQKCRESCSSPS | 1201 | Q7Z589 | |
| VTISSGSCCKPTPQL | 201 | Q3SXM5 | |
| VTTFTGEPNTCPRCS | 116 | P52943 | |
| TPPKCRSTDTSCVNP | 136 | Q03591 | |
| SVSSKNGTVCLSPPC | 201 | P09326 | |
| NGTVCLSPPCTLARS | 206 | P09326 | |
| SSTPVNLVSCDGRCP | 2856 | Q6ZRI0 | |
| CHRLTTVCPTSKPQT | 241 | P12931 | |
| FKPSLDQQRSCPTCT | 226 | Q06033 | |
| TPTLTSIYCRGCSKP | 196 | P29590 | |
| ECRSSTSPCGTSKSP | 986 | O75376 | |
| QTKSPVPLTCPSSCV | 331 | Q9H156 | |
| SCQCKLPSSEPLSRT | 161 | Q14714 | |
| VPRPPCRSKLTSCSS | 816 | Q9P2P6 | |
| CSSPGGTPASKSRLC | 91 | Q9BVR0 | |
| SPTGRRCGSCQKTPE | 481 | Q6ZVT6 | |
| RTTSAPKECSSHQPC | 111 | Q96F83 | |
| DTSCLQRTIKPLSCP | 111 | Q96LM1 | |
| KPSTTPTSRCGFCNR | 451 | Q9UM82 | |
| RKTLPGITPCESSVC | 96 | P17024 | |
| PFKCPTCRKETSATG | 51 | O60858 | |
| CSTIIPSSKNPHRCT | 26 | Q9BX84 | |
| CPCGKSTSQIPDLNT | 131 | Q9ULM2 | |
| ESEQKCPPCLTSLSQ | 626 | Q9Y5Y9 | |
| SPCQSPCVQRKLSSG | 551 | Q86UU1 | |
| SSPVPSKRTCSNCSK | 126 | Q5SVZ6 | |
| CFSTSKVPRCVNTQP | 601 | P35442 | |
| SPCSKTCRSGSLLPG | 346 | Q9C0I4 | |
| SVQCVPKATCPSSRP | 56 | Q9UI38 | |
| RSLQIPQCPTTCEKS | 1066 | P01266 | |
| PQCPTTCEKSRTSGL | 1071 | P01266 | |
| PALSTQKAQPCETCS | 76 | P17021 | |
| ACTTVTDSKGCQPQP | 401 | Q9HCK0 | |
| LATSSQELKCPTPGC | 896 | Q9UL68 |