Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

DDX12P CHD9 RECQL BTAF1 DHX30 MCM9 NAV2

7.43e-051271607GO:0008094
GeneOntologyMolecularFunctionDNA helicase activity

DDX12P RECQL DHX30 MCM9 NAV2

1.39e-04621605GO:0003678
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN8A

1.72e-04141603GO:0031402
GeneOntologyMolecularFunctionhelicase activity

DDX12P CHD9 RECQL BTAF1 DHX30 MCM9 NAV2

2.88e-041581607GO:0004386
GeneOntologyBiologicalProcesscognition

EPHB2 NRG1 MAP1A ADCY1 MFSD2A NRXN3 NRXN2 SCN2A EIF2AK4 MME ADGRF1 TNR CNR1

2.54e-0542315913GO:0050890
GeneOntologyBiologicalProcesslearning or memory

EPHB2 NRG1 MAP1A ADCY1 NRXN3 NRXN2 SCN2A EIF2AK4 MME ADGRF1 TNR CNR1

3.37e-0537315912GO:0007611
GeneOntologyCellularComponentGolgi-associated vesicle

AFTPH AP1S3 PCLO SORT1 BNIP1 AP1G1 DOP1A

2.69e-051141597GO:0005798
GeneOntologyCellularComponentsynaptic membrane

EPHB2 GABRP NRG1 ITGB4 ADCY1 PTPRT NRXN3 NRXN2 SCN1A SCN2A SCN8A UNC13C GRIN3A EPB41L1 CNR1

4.05e-0558315915GO:0097060
GeneOntologyCellularComponentaxon initial segment

MAP1A SCN1A SCN2A SCN8A

6.60e-05291594GO:0043194
GeneOntologyCellularComponentcell-cell contact zone

AKAP6 XIRP1 DSC2 PECAM1 SCN1A SCN2A

8.26e-05941596GO:0044291
GeneOntologyCellularComponentAP-1 adaptor complex

AFTPH AP1S3 AP1G1

9.03e-05121593GO:0030121
GeneOntologyCellularComponentpresynapse

EPHB2 NRG1 PCLO ADCY1 MADD SLC17A5 NRXN3 CLCN4 CLCN5 NRXN2 AP1G1 SCN1A SCN2A SCN8A UNC13C MME GRIN3A CNR1

1.44e-0488615918GO:0098793
GeneOntologyCellularComponentglutamatergic synapse

EPHB2 NRG1 PCLO DVL3 ITGB4 ADCY1 PTPRT ADD2 SORT1 SLC17A5 NRXN3 NRXN2 SCN2A SCN8A GRIN3A TNR CNR1

1.68e-0481715917GO:0098978
GeneOntologyCellularComponentintercalated disc

AKAP6 XIRP1 DSC2 SCN1A SCN2A

1.69e-04681595GO:0014704
GeneOntologyCellularComponenttrans-Golgi network transport vesicle

AFTPH AP1S3 SORT1 AP1G1

2.38e-04401594GO:0030140
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A SCN8A

2.72e-04171593GO:0001518
GeneOntologyCellularComponentpresynaptic membrane

EPHB2 NRG1 NRXN3 NRXN2 SCN1A SCN2A SCN8A UNC13C CNR1

2.79e-042771599GO:0042734
GeneOntologyCellularComponentclathrin coat of trans-Golgi network vesicle

AFTPH AP1S3 AP1G1

3.24e-04181593GO:0030130
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A SCN8A

4.48e-04201593GO:0033268
GeneOntologyCellularComponenttrans-Golgi network

AFTPH AP1S3 PCLO AP1G1 DNAAF6 MME VPS53 RIC1 DOP1A

5.74e-043061599GO:0005802
GeneOntologyCellularComponenttrans-Golgi network transport vesicle membrane

AFTPH AP1S3 AP1G1

5.98e-04221593GO:0012510
GeneOntologyCellularComponentneuron to neuron synapse

EPHB2 NRG1 MAP1A PCLO ADCY1 PTPRT ADD2 SORT1 SCN8A GRIN3A TNR EPB41L1

6.79e-0452315912GO:0098984
GeneOntologyCellularComponentpresynaptic active zone

NRG1 PCLO NRXN3 NRXN2 SCN8A UNC13C

7.42e-041411596GO:0048786
GeneOntologyCellularComponentlysosomal membrane

DAGLB AP1S3 WDR81 SORT1 SLC17A5 CLCN4 CLCN5 ABCB9 AP1G1 DEPDC5 ABCC10

8.41e-0446215911GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

DAGLB AP1S3 WDR81 SORT1 SLC17A5 CLCN4 CLCN5 ABCB9 AP1G1 DEPDC5 ABCC10

8.41e-0446215911GO:0098852
GeneOntologyCellularComponenttranscription factor TFIIIC complex

GTF3C1 GTF3C2

8.45e-0461592GO:0000127
GeneOntologyCellularComponentinterphotoreceptor matrix

RBP3 VCAN

8.45e-0461592GO:0033165
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN2A SCN8A

1.36e-03291593GO:0034706
GeneOntologyCellularComponentclathrin adaptor complex

AFTPH AP1S3 AP1G1

1.66e-03311593GO:0030131
GeneOntologyCellularComponenttrans-Golgi network membrane

AFTPH AP1S3 AP1G1 VPS53 RIC1

1.67e-031121595GO:0032588
GeneOntologyCellularComponentvesicle coat

AFTPH AP1S3 SEC24A AP1G1

1.70e-03671594GO:0030120
GeneOntologyCellularComponentvacuolar membrane

DAGLB AP1S3 WDR81 SORT1 SLC17A5 CLCN4 CLCN5 ABCB9 AP1G1 DEPDC5 ABCC10

1.77e-0350715911GO:0005774
GeneOntologyCellularComponentRNA polymerase III transcription regulator complex

GTF3C1 GTF3C2

2.00e-0391592GO:0090576
GeneOntologyCellularComponenttransport vesicle

AFTPH AP1S3 SEC24A MADD SORT1 SLC17A5 CLCN4 CLCN5 AP1G1 UNC13C MME

2.12e-0351915911GO:0030133
GeneOntologyCellularComponentGolgi apparatus subcompartment

AFTPH AP1S3 PCLO SORT1 AP1G1 DNAAF6 MME VPS53 RIC1 DOP1A

2.13e-0344315910GO:0098791
GeneOntologyCellularComponentperineuronal net

VCAN TNR

2.49e-03101592GO:0072534
GeneOntologyCellularComponentpresynaptic active zone membrane

NRG1 NRXN3 NRXN2 SCN8A

2.97e-03781594GO:0048787
GeneOntologyCellularComponentclathrin vesicle coat

AFTPH AP1S3 AP1G1

3.00e-03381593GO:0030125
GeneOntologyCellularComponentperisynaptic extracellular matrix

VCAN TNR

3.02e-03111592GO:0098966
GeneOntologyCellularComponentasymmetric synapse

NRG1 MAP1A PCLO ADCY1 PTPRT ADD2 SORT1 SCN8A GRIN3A EPB41L1

3.62e-0347715910GO:0032279
GeneOntologyCellularComponentlysosome

DAGLB AP1S3 WDR81 SORT1 SLC17A5 CLCN4 CLCN5 ABCB9 AP1G1 VCAN GZMH DEPDC5 SDC4 ABCC10

3.66e-0381115914GO:0005764
GeneOntologyCellularComponentlytic vacuole

DAGLB AP1S3 WDR81 SORT1 SLC17A5 CLCN4 CLCN5 ABCB9 AP1G1 VCAN GZMH DEPDC5 SDC4 ABCC10

3.66e-0381115914GO:0000323
GeneOntologyCellularComponentvacuole

DAGLB AP1S3 WDR81 SORT1 SLC17A5 CLCN4 CLCN5 ABCB9 AP1G1 VCAN GZMH OSBPL7 DEPDC5 SDC4 ABCC10

4.19e-0391315915GO:0005773
GeneOntologyCellularComponentsynapse-associated extracellular matrix

VCAN TNR

4.24e-03131592GO:0099535
GeneOntologyCellularComponentparallel fiber to Purkinje cell synapse

PCLO SCN8A UNC13C

4.26e-03431593GO:0098688
GeneOntologyCellularComponentmain axon

MAP1A SCN1A SCN2A SCN8A

4.77e-03891594GO:0044304
GeneOntologyCellularComponentnuclear membrane

AKAP6 ITGB4 SORT1 NPAP1 OSBPL7 PHLPP1 TMPO NUP153

5.35e-033491598GO:0031965
DomainNa_trans_cytopl

SCN1A SCN2A SCN8A

1.12e-0561563PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN8A

1.12e-0561563IPR024583
DomainSyndecan

NRXN3 NRXN2 SDC4

1.95e-0571563PF01034
DomainSyndecan/Neurexin_dom

NRXN3 NRXN2 SDC4

1.95e-0571563IPR027789
DomainNa_channel_asu

SCN1A SCN2A SCN8A

6.57e-05101563IPR001696
DomainNa_trans_assoc

SCN1A SCN2A SCN8A

6.57e-05101563IPR010526
DomainNa_trans_assoc

SCN1A SCN2A SCN8A

6.57e-05101563PF06512
DomainNeurexin-like

NRXN3 NRXN2 SDC4

1.94e-04141563IPR003585
Domain4.1m

NRXN3 NRXN2 SDC4

1.94e-04141563SM00294
DomainDishevelled_C-dom

DVL2 DVL3

2.07e-0431562IPR024580
DomainDsh_C

DVL2 DVL3

2.07e-0431562PF12316
Domain4_1_CTD

EPB41L1 EPB41L2

4.11e-0441562PF05902
DomainDishevelled

DVL2 DVL3

4.11e-0441562PF02377
DomainSAB

EPB41L1 EPB41L2

4.11e-0441562PF04382
DomainDsh/Dvl-rel

DVL2 DVL3

4.11e-0441562IPR015506
DomainBand_4.1_C

EPB41L1 EPB41L2

4.11e-0441562IPR008379
DomainSAB_dom

EPB41L1 EPB41L2

4.11e-0441562IPR007477
DomainDishevelled_fam

DVL2 DVL3

4.11e-0441562IPR008339
DomainDishevelled_protein_dom

DVL2 DVL3

4.11e-0441562IPR003351
DomainConA-like_dom

ITGB4 ADGRG4 PTPRT RYR3 COL24A1 NRXN3 NRXN2 MID1

5.17e-042191568IPR013320
DomainDEP

DVL2 DVL3 DEPDC5

7.83e-04221563PF00610
DomainDEP

DVL2 DVL3 DEPDC5

7.83e-04221563PS50186
DomainSEA

MUC16 MUC17 ADGRF1

7.83e-04221563PF01390
DomainDEP

DVL2 DVL3 DEPDC5

7.83e-04221563SM00049
DomainDEP_dom

DVL2 DVL3 DEPDC5

8.95e-04231563IPR000591
DomainSEA

MUC16 MUC17 ADGRF1

8.95e-04231563PS50024
DomainSEA_dom

MUC16 MUC17 ADGRF1

8.95e-04231563IPR000082
DomainUbiquitin-rel_dom

FRMPD1 USP24 DVL2 DVL3 MIDN EPB41L1 EPB41L2

9.12e-041841567IPR029071
DomainAAA

DNAH7 ABCA10 ABCB9 MCM9 NAV2 ABCC10

1.33e-031441566SM00382
DomainAAA+_ATPase

DNAH7 ABCA10 ABCB9 MCM9 NAV2 ABCC10

1.33e-031441566IPR003593
DomainZnf_MYM

ZMYM2 ZMYM1

1.42e-0371562IPR010507
DomainDIX

DVL2 DVL3

1.42e-0371562PF00778
Domainzf-FCS

ZMYM2 ZMYM1

1.42e-0371562PF06467
DomainDIX

DVL2 DVL3

1.42e-0371562IPR001158
DomainDIX

DVL2 DVL3

1.42e-0371562PS50841
DomainDAX

DVL2 DVL3

1.42e-0371562SM00021
DomainPDZ

LNX2 PCLO FRMPD1 DVL2 DVL3 TIAM2

1.70e-031511566PS50106
DomainPDZ

LNX2 PCLO FRMPD1 DVL2 DVL3 TIAM2

1.76e-031521566IPR001478
DomainEGF_2

EPHB2 NRG1 ITGB4 NRXN3 NRXN2 MUC17 VCAN TNR

1.76e-032651568PS01186
DomainTRASH_dom

ZMYM2 ZMYM1

1.88e-0381562IPR011017
DomainTRASH

ZMYM2 ZMYM1

1.88e-0381562SM00746
DomainHATC_C_dom

ZBED4 ZMYM1

1.88e-0381562IPR008906
DomainDimer_Tnp_hAT

ZBED4 ZMYM1

1.88e-0381562PF05699
DomainCalx_beta

FRAS1 ITGB4

1.88e-0381562SM00237
DomainCalx_beta

FRAS1 ITGB4

2.40e-0391562IPR003644
DomainCl-channel_core

CLCN4 CLCN5

2.40e-0391562IPR014743
Domain-

CLCN4 CLCN5

2.40e-03915621.10.3080.10
DomainVoltage_CLC

CLCN4 CLCN5

2.40e-0391562PF00654
DomainCl-channel_volt-gated

CLCN4 CLCN5

2.40e-0391562IPR001807
DomainCalx-beta

FRAS1 ITGB4

2.40e-0391562PF03160
DomainFERM_N

FRMPD1 EPB41L1 EPB41L2

2.59e-03331563IPR018979
DomainFERM_N

FRMPD1 EPB41L1 EPB41L2

2.59e-03331563PF09379
DomainIon_trans_dom

KCNB2 RYR3 SCN1A SCN2A SCN8A

2.70e-031141565IPR005821
DomainIon_trans

KCNB2 RYR3 SCN1A SCN2A SCN8A

2.70e-031141565PF00520
DomainEGF

NRG1 FRAS1 NRXN3 NRXN2 MUC17 VCAN TNR

3.65e-032351567SM00181
DomainLAM_G_DOMAIN

COL24A1 NRXN3 NRXN2

3.89e-03381563PS50025
Domain-

MBNL1 ZFP36L1 MBNL3

4.50e-034015634.10.1000.10
DomainLaminin_G_2

COL24A1 NRXN3 NRXN2

4.50e-03401563PF02210
DomainEGF-like_dom

NRG1 FRAS1 NRXN3 NRXN2 MUC17 VCAN TNR

4.99e-032491567IPR000742
DomainFA

EPB41L1 EPB41L2

5.09e-03131562PF08736
DomainFERM-adjacent

EPB41L1 EPB41L2

5.09e-03131562IPR014847
DomainFA

EPB41L1 EPB41L2

5.09e-03131562SM01195
DomainABC_transporter_CS

ABCA10 ABCB9 ABCC10

5.17e-03421563IPR017871
DomainEGF_1

NRG1 ITGB4 NRXN3 NRXN2 MUC17 VCAN TNR

5.67e-032551567PS00022
DomainSEA

MUC16 MUC17

5.91e-03141562SM00200
DomainEGF-like_CS

NRG1 ITGB4 NRXN3 NRXN2 MUC17 VCAN TNR

6.42e-032611567IPR013032
DomainPDZ

LNX2 FRMPD1 DVL2 DVL3 TIAM2

6.64e-031411565PF00595
DomainFERM_M

FRMPD1 EPB41L1 EPB41L2

6.67e-03461563PF00373
Domain-

MUC16 MUC17

6.78e-031515623.30.70.960
DomainZnF_C3H1

MBNL1 ZFP36L1 MBNL3

7.51e-03481563SM00356
DomainABC_tran

ABCA10 ABCB9 ABCC10

7.51e-03481563PF00005
DomainHEAT

PPP4R1 BTAF1 GCN1

7.51e-03481563PF02985
DomainABC_TRANSPORTER_2

ABCA10 ABCB9 ABCC10

7.51e-03481563PS50893
DomainCBS

CLCN4 CLCN5

7.70e-03161562SM00116
DomainARM-type_fold

PPP4R1 DOCK8 USP24 BTAF1 RYR3 THADA AP1G1 GCN1

7.74e-033391568IPR016024
Domainzf-CCCH

MBNL1 ZFP36L1 MBNL3

7.95e-03491563PF00642
Domain-

FRMPD1 EPB41L1 EPB41L2

7.95e-034915631.20.80.10
DomainABC_TRANSPORTER_1

ABCA10 ABCB9 ABCC10

7.95e-03491563PS00211
DomainFERM_central

FRMPD1 EPB41L1 EPB41L2

7.95e-03491563IPR019748
DomainFERM_domain

FRMPD1 EPB41L1 EPB41L2

7.95e-03491563IPR000299
DomainPDZ

LNX2 FRMPD1 DVL2 DVL3 TIAM2

8.10e-031481565SM00228
Domain-

ADGRG4 COL24A1 NRXN3 NRXN2

8.28e-039515642.60.120.200
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PPP4R1 MIA3 SEC24A RALGAPB KIAA1549 PTPRT ADD2 MADD FAN1 SORT1 CEP350 TMF1 PHLPP1 TMPO ANKRD28 EIF2AK4 MPHOSPH9 IK MAPK9 GCN1 CNOT1 EPB41L1 NUP153

6.05e-1010491602327880917
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

NRG1 NCKAP1 CHD9 RECQL CEP76 RYR3 MIDN GTF3C1 NAV2 TMPO ANKRD28 EIF2AK4 IK CNOT1 WNK4 RIC1

1.47e-094971601636774506
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

HIVEP2 ARHGEF28 AFTPH DSC2 NCKAP1 SEC24A RALGAPB DNAH7 MADD CEP350 ZFP36L1 KIAA1217 NAV2 AKAP11 MPHOSPH9 WNK4 EPB41L1 EPB41L2 DOP1A

1.92e-088611601936931259
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AKAP6 HECTD4 KIAA1549 RNF40 TIAM2 NRXN3 GTF3C2 NRXN2 NAV2 AKAP11 HMGXB3 DEPDC5 EIF2AK4 CNOT1 RAD21

2.63e-085291601514621295
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PPP4R1 FRAS1 MIA3 ARHGEF28 RALGAPB BTAF1 MADD PARP4 GTF3C1 AP1G1 MID1 ANKRD28 PLCB3 EIF2AK4 EPB41L1 RIC1

6.24e-086501601638777146
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NCKAP1 USP24 RECQL DHX30 IARS2 GTF3C1 BYSL ANKRD28 ATIC IK GCN1 CNOT1 NUP153 EPB41L2 SON RAD21

6.64e-086531601622586326
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A SCN8A

9.56e-083160332845893
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A SCN8A

9.56e-083160328518218
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A SCN8A

9.56e-083160317928448
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

AKAP6 DMTF1 MIA3 MBNL1 FRMPD1 ITGB4 AKAP12 TIAM2 MADD AP1G1 VCAN MYPN AEBP2 HMGXB3 CEP295 EIF2AK4 ZMYM1 IK CNOT1 NUP153

1.46e-0710841602011544199
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ATMIN FRAS1 HIVEP2 RARG HECTD4 RNF40 BTAF1 ITGB4 TIAM2 MADD DHX30 THADA ZBED4 SCN8A NAV2 HMGXB3 DEPDC5 GCN1 ABCC10 RIC1

1.99e-0711051602035748872
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

AFTPH MAP1A DVL2 ZMYM2 BTAF1 AKAP12 DHX30 IARS2 KIAA1217 TMPO ANKRD28 PRR14L ATIC GCN1 NUP153 EPB41L2 SON RAD21

3.44e-079341601833916271
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN8A

3.81e-074160317537961
Pubmed

Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins.

NRXN3 NRXN2 GRIN3A

3.81e-074160314983056
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN8A

3.81e-074160335031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN8A

3.81e-074160329578003
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A SCN8A

3.81e-074160321156207
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

MIA3 SEC24A DVL2 DVL3 KIAA1549 KCNB2 KIAA1217 GCN1 CNOT1 NUP153

4.34e-072631601034702444
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

AFTPH USP24 ZMYM2 ITGB4 GTF3C1 GTF3C2 MYPN NAV2 TMF1 EPB41L1 NUP153 EPB41L2 SON

6.61e-075031601316964243
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

EPHB2 ATMIN PPP4R1 OR2F2 ARHGEF28 MBNL1 RALGAPB DHX30 MFSD2A PRDM10 ZBED4 MCM9 PTAR1 NPAP1 AEBP2 PHLPP1 DEPDC5 EIF2AK4 ATIC GCN1 CNOT1

8.57e-0713271602132694731
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

PCLO TMEM132B PARP4 GTF3C1 ZBED4 GZMH SCN8A TMPO CEP295 PLCB3 ATIC MAPK9 TNR CNOT1 EPB41L2

1.75e-067361601529676528
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

DAGLB MIA3 DSC2 NCKAP1 USP24 DVL2 BTAF1 SORT1 THADA BNIP1 AP1G1 BYSL TMPO ATIC GCN1 VPS53 NUP153

1.81e-069421601731073040
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN8A

1.89e-066160323652591
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

SEC24A HECTD4 USP24 PARP4 AP1G1 AKAP11 EIF2AK4 VPS53

2.28e-06183160831932471
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

NCKAP1 FRMPD1 DVL2 ZMYM2 RECQL BTAF1 E4F1 SORT1 IARS2 PRDM10 GTF3C1 GTF3C2 NFIL3 TMF1 ANKRD28 MAPK9

2.41e-068571601625609649
Pubmed

A human MAP kinase interactome.

HIVEP2 MAP1A ZMYM2 ITGB4 MADD CEP350 NAV2 MPHOSPH9 MAPK9 GCN1 NUP153 EPB41L2

2.88e-064861601220936779
Pubmed

The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.

MAP1A NCKAP1 SEC24A RECQL DHX30 PARP4 GTF3C1 AKAP11 PLCB3 CNOT1

2.92e-063251601036168628
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PCLO MBNL1 CHD9 ABCB9 PHLPP1 GCN1

3.20e-0687160612465718
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A SCN8A

3.30e-067160325818041
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

DSC2 CCDC30 SEC24A MUC16 DNAH7 AKAP12 CEP350 IARS2 THADA TMF1 TMPO ANKRD28 MPHOSPH9 GCN1 EPB41L2

3.38e-067771601535844135
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

USP24 DVL2 DVL3 ZMYM2 RNF40 GTF3C1 GTF3C2 TMF1 ANKRD28 GCN1 CNOT1

4.15e-064181601134709266
Pubmed

Myocardial Angiopoietin-1 Controls Atrial Chamber Morphogenesis by Spatiotemporal Degradation of Cardiac Jelly.

NRG1 PECAM1 ADAMTS5 VCAN

4.27e-0624160429791855
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

BTAF1 ITGB4 DHX30 PARP4 TMPO EIF2AK4 GCN1 CNOT1

4.73e-06202160833005030
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

FRAS1 MIA3 AFTPH DSC2 RALGAPB KIAA1549 PDHX AKAP12 ADD2 DHX30 IARS2 THADA BNIP1 GTF3C2 BYSL TMPO ANKRD28 AKAP11 EPB41L1 EPB41L2 RAD21

5.09e-0614871602133957083
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

DSC2 NCKAP1 SEC24A USP24 DVL2 AKAP12 ADD2 TMPO MPHOSPH9 GCN1 CNOT1 EPB41L1 NUP153 EPB41L2

5.54e-067081601439231216
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

PPP4R1 AFTPH SEC24A DVL2 DVL3 WDR81 MADD CEP350 RIMKLB AP1G1 ZFP36L1 KIAA1217 MYPN BYSL MPHOSPH9 IK CNOT1

6.55e-0610381601726673895
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

MIA3 LNX2 NCKAP1 DOCK8 RALGAPB KIAA1549 ANKRD28 CEP295 MPHOSPH9 CNOT1 RAD21

7.65e-064461601124255178
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A SCN8A

7.87e-069160316382098
Pubmed

Anchoring and scaffold proteins for kinases and phosphatases.

AKAP6 AKAP12 AKAP11

7.87e-06916039238861
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN8A

7.87e-069160315746173
Pubmed

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.

EPHB2 NRXN3 NRXN2

7.87e-06916039707552
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MAP1A NCKAP1 DOCK8 PCLO RBP3 KIAA1549 PDHX ADD2 MADD DHX30 NRXN2 AP1G1 KIAA1217 VCAN SCN2A TMPO TNR CNOT1 EPB41L1 EPB41L2

1.01e-0514311602037142655
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

AKAP6 RALGAPB NRXN2 NAV2 PHLPP1 ANKRD28 AKAP11 GCN1

1.04e-05225160812168954
Pubmed

AKAP mediated signal transduction.

AKAP6 AKAP12 AKAP11

1.12e-0510160311807172
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

NCKAP1 ZMYM2 SORT1 PRDM10 GTF3C2 AP1G1 TMPO ANKRD28 IK CNOT1 EPB41L2 RAD21

1.20e-055601601235241646
Pubmed

Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.

DVL2 DVL3 MADD FAN1 TMF1 TMPO ANKRD28

1.31e-05167160725659891
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

MIA3 DSC2 SEC24A DVL2 DVL3 AKAP12 BNIP1 TMF1 TMPO PRR14L GCN1 NUP153

1.38e-055681601237774976
Pubmed

Zinc transporter Slc39a8 is essential for cardiac ventricular compaction.

PECAM1 ADAMTS5 VCAN

1.53e-0511160329337306
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ATMIN MIA3 HIVEP2 ZBTB20 MBNL1 RALGAPB FRMPD1 HECTD4 CHD9 BTAF1 ADCY1 THADA GTF3C1 KIAA1217 EIF2AK4 MME CNOT1 EPB41L1 RIC1 DOP1A

1.79e-0514891602028611215
Pubmed

Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican.

PECAM1 ADAMTS5 VCAN

2.04e-0512160332648916
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN8A

2.04e-0512160330175250
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ATMIN FRAS1 NCKAP1 RALGAPB FRMPD1 MADD DHX30 ZBED4 EPB41L1 SON

2.07e-054071601012693553
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

2.10e-052160237901435
Pubmed

Common variants of NRG1 and ITGB4 confer risk of Hirschsprung disease in Han Chinese population.

NRG1 ITGB4

2.10e-052160232418639
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

2.10e-052160226410685
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

2.10e-052160210827969
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

2.10e-052160219694741
Pubmed

Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.

SCN2A SCN8A

2.10e-052160235348308
Pubmed

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.

SCN2A SCN8A

2.10e-052160215760941
Pubmed

Identification and functional characterization of a voltage-gated chloride channel and its novel splice variant in taste bud cells.

CLCN4 CLCN5

2.10e-052160216129671
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

2.10e-05216021317301
Pubmed

Novel treatment option for MUC16-positive malignancies with the targeted TRAIL-based fusion protein Meso-TR3.

TNFSF10 MUC16

2.10e-052160224447304
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

2.10e-052160231439038
Pubmed

TRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis.

TNFSF10 MID1

2.10e-052160230732588
Pubmed

The expression pattern of CD10 and CD31 identifies fine fibrovascular stroma of grade 1-endometrial endometrioid carcinomas in cytology.

PECAM1 MME

2.10e-052160234689374
Pubmed

Genetic analysis of disheveled 2 and disheveled 3 in human neural tube defects.

DVL2 DVL3

2.10e-052160222892949
Pubmed

Pericellular versican regulates the fibroblast-myofibroblast transition: a role for ADAMTS5 protease-mediated proteolysis.

ADAMTS5 VCAN

2.10e-052160221828051
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

2.10e-052160231943325
Pubmed

Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis.

ADAMTS5 SDC4

2.10e-052160219684582
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

2.10e-052160215249644
Pubmed

The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression.

EPB41L1 EPB41L2

2.10e-052160219225127
Pubmed

Neuronal neprilysin overexpression is associated with attenuation of Abeta-related spatial memory deficit.

ZBTB20 MME

2.10e-052160217008108
Pubmed

ADAMTS5 Is a Critical Regulator of Virus-Specific T Cell Immunity.

ADAMTS5 VCAN

2.10e-052160227855162
Pubmed

Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.

SCN2A SCN8A

2.10e-052160218601978
Pubmed

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.

SCN2A SCN8A

2.10e-052160219465131
Pubmed

Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy.

MBNL1 MBNL3

2.10e-052160210970838
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

2.10e-052160230693367
Pubmed

Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.

CLCN4 CLCN5

2.10e-052160216034421
Pubmed

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

SCN2A SCN8A

2.10e-052160223735284
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

2.10e-052160229649454
Pubmed

MADD knock-down enhances doxorubicin and TRAIL induced apoptosis in breast cancer cells.

TNFSF10 MADD

2.10e-052160223457619
Pubmed

Tiam-Rac signaling mediates trans-endocytosis of ephrin receptor EphB2 and is important for cell repulsion.

EPHB2 TIAM2

2.10e-052160227597758
Pubmed

Membrane metallo-endopeptidase is dispensable for repair after nerve injury.

NRG1 MME

2.10e-052160231339187
Pubmed

Interactions between adaptor protein-1 of the clathrin coat and microtubules via type 1a microtubule-associated proteins.

MAP1A AP1G1

2.10e-052160211418592
Pubmed

Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-gamma.

RARG CNR1

2.10e-052160220410309
Pubmed

Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice.

ZBTB20 MME

2.10e-052160219228952
Pubmed

Planar polarization of node cells determines the rotational axis of node cilia.

DVL2 DVL3

2.10e-052160220098415
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

2.10e-052160233096315
Pubmed

Disheveled proteins promote cell growth and tumorigenicity in ALK-positive anaplastic large cell lymphoma.

DVL2 DVL3

2.10e-052160223022960
Pubmed

Sodium channel expression within chronic multiple sclerosis plaques.

SCN2A SCN8A

2.10e-052160217805013
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

2.10e-052160226311622
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

2.10e-052160233411788
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

2.10e-052160221377452
Pubmed

ARE-binding protein ZFP36L1 interacts with CNOT1 to directly repress translation via a deadenylation-independent mechanism.

ZFP36L1 CNOT1

2.10e-052160232311426
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

2.10e-052160237665666
Pubmed

Nav1.1-Overexpressing Interneuron Transplants Restore Brain Rhythms and Cognition in a Mouse Model of Alzheimer's Disease.

ZBTB20 SCN1A

2.10e-052160229551491
Pubmed

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

SCN1A SCN8A

2.10e-052160217881658
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

MIA3 MAP1A NCKAP1 PCLO USP24 DVL2 DVL3 KCNB2 PDHX MADD SCN1A KIAA1217 ANKRD28 GCN1 CNOT1 EPB41L1 EPB41L2

2.16e-0511391601736417873
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

MIA3 ADD2 CEP350 TMF1 AKAP11 MPHOSPH9 CNOT1 VPS53

2.29e-05251160829778605
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN8A

2.64e-0513160315123669
InteractionFBXO22 interactions

NRG1 NCKAP1 CHD9 RECQL CEP76 RYR3 MIDN GTF3C1 NAV2 PHLPP1 TMPO ANKRD28 EIF2AK4 IK CNOT1 WNK4 RIC1

1.13e-0654015717int:FBXO22
InteractionYWHAQ interactions

HIVEP2 ARHGEF28 AFTPH ZBTB17 DSC2 NCKAP1 SEC24A HECTD4 DVL2 DNAH7 ITGB4 CEP350 IARS2 ZFP36L1 USP42 NAV2 TMPO AKAP11 MPHOSPH9 GCN1 WNK4 EPB41L1 EPB41L2 DOP1A

6.00e-06111815724int:YWHAQ
InteractionSDC2 interactions

EPHB2 ITGB4 PRDM10 GTF3C1 GTF3C2 TMPO SDC4 EPB41L1

1.66e-051431578int:SDC2
InteractionSCN4B interactions

SCN1A SCN2A SCN8A

2.52e-0581573int:SCN4B
InteractionYWHAG interactions

LNX2 HIVEP2 ARHGEF28 AFTPH DSC2 NCKAP1 SEC24A RALGAPB HECTD4 USP24 DVL2 DNAH7 CEP350 IARS2 ZFP36L1 OSBPL7 NAV2 AKAP11 MPHOSPH9 ATIC EPB41L1 EPB41L2 DOP1A SON

3.65e-05124815724int:YWHAG
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A SCN8A

1.56e-05910531203
GeneFamilyDishevelled segment polarity proteins|PDZ domain containing

DVL2 DVL3

1.99e-0441052505
GeneFamilyErythrocyte membrane protein band 4.1|FERM domain containing

EPB41L1 EPB41L2

1.99e-0441052951
GeneFamilyPDZ domain containing

LNX2 PCLO FRMPD1 DVL2 DVL3 TIAM2

2.60e-0415210561220
GeneFamilyZinc fingers MYM-type

ZMYM2 ZMYM1

4.94e-046105286
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

AKAP6 AKAP12 AKAP11

6.23e-04291053396
GeneFamilyChloride voltage-gated channels

CLCN4 CLCN5

1.46e-03101052302
GeneFamilyFibronectin type III domain containing

EPHB2 ITGB4 PTPRT MID1 TNR

2.42e-031601055555
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

FRMPD1 EPB41L1 EPB41L2

3.06e-035010531293
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

EPHB2 NRG1 HIVEP2 ZBTB20 NCKAP1 SEC24A MBNL1 USP24 ZMYM2 CHD9 BTAF1 CEP350 GTF3C2 MID1 PHLPP1 ANKRD28 AKAP11 MPHOSPH9 NUP153 SON

2.97e-0785616020M4500
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

DOCK8 USP24 CEP350 PRDM10 GTF3C1 DEPDC5 PRR14L RIC1 RAD21

1.72e-061801609M8239
CoexpressionSESTO_RESPONSE_TO_UV_C5

PPP4R1 ITGB4 GTF3C2 MME SDC4

8.91e-06461605M1470
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

AKAP6 MIA3 AP1S3 PCLO KIAA1549 TMEM132B ADCY1 PTPRT NRXN3 CLCN4 NRXN2 SCN1A VCAN SCN2A SCN8A GRIN3A VPS53 EPB41L1 CNR1 DOP1A

1.43e-05110616020M39071
CoexpressionGSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_3H_UP

HIVEP2 KCNB2 MFSD2A BNIP1 USP42 MUC17 POC1B GRIN3A

2.13e-051881608M6167
CoexpressionGSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_DN

EPHB2 PPP4R1 PCLO PTPRT NRXN2 SCN1A DNAI4 PRR14L

2.66e-051941608M8864
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBGABA

PCLO ADAMTS5 TMEM132B ADCY1 PTPRT NRXN3 NRXN2 NFIL3 SCN1A SCN2A SCN8A GRIN3A EPB41L1 CNR1 DOP1A

2.84e-0570316015M39070
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

ZBTB20 CEP350 ANKRD28 AKAP11 MPHOSPH9 MME FASTKD3

2.89e-051431607M9149
CoexpressionGSE21379_TFH_VS_NON_TFH_CD4_TCELL_DN

HIVEP2 RBP3 DNAH7 CLCN5 USP42 PCDHB1 CEACAM20 EPB41L1

3.31e-052001608M7508
CoexpressionLAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX

ZBTB20 ARHGEF28 DOCK8 MBNL1 NRXN3 KIAA1217 ADGRF1

4.27e-051521607M39239
CoexpressionLIN_SILENCED_BY_TUMOR_MICROENVIRONMENT

GABRP DSC2 MUC16 SLC17A5 ADGRF1 EPB41L1

5.12e-051071606M19768
CoexpressionGSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN

DMTF1 CHD9 PRDM10 OSBPL7 NAV2 DEPDC5 SON

7.45e-051661607M6826
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

DMTF1 HIVEP2 USP24 CHD9 CEP350 ZBED4 PHLPP1 NUP153 DOP1A

9.97e-053001609M8702
CoexpressionXIE_TRASTUZUMAB_CARDIOTOXICITY_CIRCRNA_GENES

AKAP6 AFTPH PECAM1 BTAF1

1.03e-04401604MM17488
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

DMTF1 HIVEP2 DOCK8 PECAM1 MBNL1 RALGAPB HECTD4 USP24 BTAF1 CEP350 ZFP36L1 USP42 GZMH PTAR1 TMF1 ANKRD28 AKAP11 IK CNOT1 NUP153 SON RAD21

1.12e-04149216022M40023
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

NRG1 HIVEP2 SEC24A MBNL1 USP24 ZMYM2 CHD9 CEP350 MID1 PHLPP1 NUP153

1.44e-0446616011M13522
CoexpressionGSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP

USP24 MADD MIDN ZBED4 USP42 NFIL3 PHLPP1

1.73e-041901607M3289
CoexpressionHEVNER_CORTICAL_PLATE_POSTMITOTIC_NEURONS

PCLO KIAA1549 MADD NFIL3 SCN8A MAPK9

1.93e-041361606MM407
CoexpressionCHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN

DMTF1 ZBTB20 AP1S3 CCDC30 TNFSF10 PCLO AKAP12 PARP4 NRXN3 DNAI4

2.10e-0440716010M2214
CoexpressionACEVEDO_LIVER_CANCER_WITH_H3K9ME3_UP

OR2F2 OR2F1 NRXN3 GTF3C2 VCAN MME

2.17e-041391606M6754
CoexpressionTIEN_INTESTINE_PROBIOTICS_2HR_DN

PPP4R1 RECQL CEP76 PDHX CLCN4

2.19e-04891605M8916
CoexpressionIVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR

AKAP6 TNFSF10 RALGAPB DVL3 KIAA1549 ITGB4 SLC17A5 MIDN GZMH SCN8A BYSL CNOT1

2.22e-0457416012M8215
CoexpressionGSE22601_DOUBLE_NEGATIVE_VS_IMMATURE_CD4_SP_THYMOCYTE_DN

DVL2 CALML6 AKAP12 BICDL1 BYSL ATIC EPB41L2

2.22e-041981607M6228
CoexpressionGSE36009_WT_VS_NLRP10_KO_DC_LPS_STIM_UP

TNFSF10 PARP4 CLCN4 ZFP36L1 TMPO DNAI4 EPB41L2

2.29e-041991607M8769
CoexpressionGSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN

AFTPH TNFSF10 CHD9 SLC17A5 TMF1 CNOT1 SON

2.29e-041991607M5799
CoexpressionGSE14308_NAIVE_CD4_TCELL_VS_NATURAL_TREG_DN

AP1S3 CHD9 MCM9 ZMYM1 MAPK9 EPB41L2 RAD21

2.36e-042001607M3394
CoexpressionGSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_DN

RARG PECAM1 USP24 ZMYM2 AKAP12 MADD ABCB9

2.36e-042001607M7186
CoexpressionGSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN

ZBTB20 RARG USP24 ZMYM2 PARP4 PHLPP1 SDC4

2.36e-042001607M9765
CoexpressionGSE29164_DAY3_VS_DAY7_CD8_TCELL_TREATED_MELANOMA_DN

GABRP PECAM1 SORT1 OSBPL7 TMPO ATIC RIC1

2.36e-042001607M8494
CoexpressionGSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_UP

MIA3 RALGAPB AKAP12 MIDN NFIL3 AEBP2 PHLPP1

2.36e-042001607M8705
CoexpressionGSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_3H_DN

WDR81 AKAP12 MFSD2A PRDM10 AEBP2 PLCB3 MAPK9

2.36e-042001607M6414
CoexpressionHALLMARK_APICAL_JUNCTION

PECAM1 ADAMTS5 ITGB4 NRXN2 VCAN WNK4 EPB41L2

2.36e-042001607M5915
CoexpressionGSE20366_TREG_VS_NAIVE_CD4_TCELL_UP

SEC24A DNAH7 TMF1 PHLPP1 DNAI4 SDC4 MBNL3

2.36e-042001607M4347
CoexpressionGSE7460_TREG_VS_TCONV_ACT_UP

TNFSF10 SEC24A DNAH7 ZFP36L1 PTAR1 FES SDC4

2.36e-042001607M5690
CoexpressionNAKAYA_MYELOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN

AKAP6 ZBTB17 MAP1A RALGAPB BNIP1 CLCN5 MID1 NUP153

2.46e-042671608M41130
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

DMTF1 SEC24A PCLO USP24 CHD9 CEP76 ZNF711 GTF3C1 NRXN2 USP42 AEBP2 TMPO DEPDC5 CEP295 EIF2AK4 SON RAD21

1.75e-0659515517Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

EPHB2 NRG1 LNX2 ZBTB20 AFTPH MAP1A TNFSF10 PCLO DVL2 ZMYM2 CEP76 SORT1 MFSD2A RIMKLB NRXN2 NAV2 PHLPP1 DNAI4 CEP295 MPHOSPH9 CEACAM20

1.09e-0598915521Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

ZBTB20 SEC24A USP24 ZMYM2 CHD9 ZNF711 GTF3C1 USP42 TMPO DEPDC5 CEP295 EIF2AK4 ZMYM1 EPB41L1 SON RAD21

1.53e-0562915516Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

EPHB2 MAP1A AP1S3 ZMYM2 KIAA1549 CHD9 CEP76 MADD DHX30 ZNF711 MFSD2A IARS2 RIMKLB ZBED4 MID1 SCN8A PHLPP1 DNAI4 CEP295 ZMYM1 CNR1

3.04e-05106015521facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

EPHB2 NRG1 LNX2 ZBTB20 AFTPH MAP1A PCLO BTAF1 MADD CEP350 MFSD2A RIMKLB NRXN3 NRXN2 MID1 TMF1 PHLPP1 ANKRD28 MME DOP1A

3.29e-0598315520Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_1000

ZBTB20 ADAMTS5 PTPRT NRXN3 SCN2A TNR

5.49e-05911556gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

EPHB2 MAP1A AP1S3 TNFSF10 ZMYM2 KIAA1549 CHD9 CEP76 ADD2 MADD DHX30 ZNF711 MFSD2A IARS2 RIMKLB NRXN3 ZBED4 MID1 SCN8A PHLPP1 DNAI4 CEP295 ZMYM1 CNR1

9.29e-05141415524facebase_RNAseq_e10.5_Emin_MedNas_2500
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO ADCY1 NRXN3 NRXN2 SCN1A SCN2A SCN8A UNC13C CNR1

2.94e-081891609f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 PCLO ADCY1 MADD NRXN3 NRXN2 SCN1A SCN2A SCN8A

3.52e-081931609be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 ARHGEF28 CCDC30 PCLO DNAH7 BICDL1 CLCN5 MME EPB41L1

3.52e-08193160982e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 PCLO ADCY1 MADD NRXN3 NRXN2 SCN1A SCN2A SCN8A

3.52e-0819316090c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 PCLO ADCY1 MADD NRXN3 NRXN2 SCN1A SCN2A SCN8A

3.52e-0819316098689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO ADCY1 NRXN3 NRXN2 SCN1A SCN2A SCN8A UNC13C CNR1

3.52e-0819316095fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 ARHGEF28 CCDC30 PCLO DNAH7 BICDL1 CLCN5 SDC4 EPB41L1

3.68e-0819416095eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ARHGEF28 DSC2 NCKAP1 MUC16 ADCY1 PTPRT RYR3 MYPN MME

3.84e-081951609d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ARHGEF28 DSC2 NCKAP1 MUC16 ADCY1 PTPRT RYR3 MYPN MME

3.84e-08195160919853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PPP4R1 GABRP ARHGEF28 NCKAP1 MUC16 KIAA1217 ADGRF1 SDC4 EPB41L1

4.38e-081981609a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARHGEF28 NCKAP1 PCLO MUC16 ITGB4 KIAA1217 ADGRF1 SDC4 EPB41L1

4.78e-082001609ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 HIVEP2 PCLO PTPRT RYR3 COL24A1 NRXN3 UNC13C

1.84e-07169160812bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

HIVEP2 RALGAPB NRXN2 VCAN MME IK SDC4 EPB41L1

2.74e-071781608edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 FRAS1 ARHGEF28 KIAA1549 SLC22A24 DNAH7 BICDL1 SLC13A1

3.38e-0718316086878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

GABRP ARHGEF28 MUC16 ITGB4 MUC17 SCN2A EPB41L1 MGAM2

3.38e-07183160815d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG1 ADCY1 NRXN3 SCN1A SCN2A SCN8A UNC13C CNR1

3.99e-0718716087b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 FRAS1 ARHGEF28 PCLO BICDL1 SLC13A1 SCN2A EPB41L1

3.99e-071871608d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 AP1S3 TNFSF10 DNAH7 RIMKLB MIDN VCAN SDC4

5.07e-071931608ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 ARHGEF28 CCDC30 PCLO DNAH7 BICDL1 CLCN5 EPB41L1

5.07e-0719316083866667dd221612589ae50f5c52f73a183a49ce6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GABRP ARHGEF28 AP1S3 DNAH7 PARP4 DNAI4 ADGRF1 EPB41L1

5.27e-071941608e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 ARHGEF28 CCDC30 PCLO DNAH7 BICDL1 CLCN5 EPB41L1

5.27e-07194160893c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 ARHGEF28 CCDC30 PCLO DNAH7 BICDL1 CLCN5 EPB41L1

5.48e-0719516086477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 ARHGEF28 CCDC30 PCLO DNAH7 BICDL1 CLCN5 EPB41L1

5.70e-0719616086ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ARHGEF28 NCKAP1 PCLO ITGB4 KIAA1217 ADGRF1 SDC4 EPB41L1

6.63e-07200160897f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellKidney-Tubules|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.

ZBTB20 BICDL1 CLCN5 NAV2 ADGRF1 SDC4 WNK4 EPB41L1

6.63e-0720016080726456906e078244a9cff35aee8c5bce4566fb1
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 DSC2 PCLO MUC16 ITGB4 ADD2 BICDL1

2.58e-061681607e870d2e69316406f45112ed0bf324b24f902a99e
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 DSC2 PCLO MUC16 ITGB4 ADD2 BICDL1

2.58e-061681607403aba73a0f9ffb32252288d075fad8a588ca440
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 PCLO KIAA1549 SLC22A24 BICDL1 SLC13A1 MME

3.78e-06178160723a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO ADCY1 NRXN3 SCN1A SCN2A UNC13C CNR1

4.07e-061801607f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRAS1 ARHGEF28 PCLO BICDL1 SLC13A1 SCN2A EPB41L1

4.37e-0618216079d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

NRG1 TNFSF10 DOCK8 KIAA1549 SLC22A24 BICDL1 SLC13A1

4.70e-06184160751ed1ebfdef45149541917c66cbacad87072e51f
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

GABRP ARHGEF28 MUC16 ITGB4 MUC17 ADGRF1 MGAM2

4.70e-061841607d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO ADCY1 NRXN3 SCN1A SCN2A SCN8A CNR1

4.70e-0618416077d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO ADCY1 NRXN3 NRXN2 SCN2A UNC13C CNR1

5.04e-061861607d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC30 USP24 ZMYM2 ADAMTS5 SLC17A5 AEBP2 ZMYM1

5.41e-0618816076468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC30 USP24 ZMYM2 ADAMTS5 SLC17A5 AEBP2 ZMYM1

5.41e-0618816077a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

AKAP6 ARHGEF28 MBNL1 RYR3 SORT1 MID1 UNC13C

5.41e-06188160734e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC30 USP24 ZMYM2 ADAMTS5 SLC17A5 AEBP2 ZMYM1

5.41e-0618816079cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

AKAP6 ARHGEF28 MBNL1 RYR3 SORT1 MID1 UNC13C

5.60e-0618916076b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 GABRP AP1S3 DNAH7 NAV2 ADGRF1 EPB41L1

5.80e-0619016073fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 GABRP AP1S3 DNAH7 NAV2 ADGRF1 EPB41L1

6.00e-0619116075a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 GABRP AP1S3 DNAH7 NAV2 ADGRF1 EPB41L1

6.00e-06191160755ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRG1 FRMPD1 PTPRT SCN1A VCAN UNC13C GRIN3A

6.21e-06192160763d1b3efe93e5ff939278ebe40bacb38218ea09b
ToppCellControl-B_naive-11|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TMPO DNAAF6 UNC13C FASTKD3 ADGRF1 EPB41L2

6.38e-061261606319a4c325e0e5c14bb49a143b8924c554f834cc0
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 MBNL1 USP24 CHD9 CEP350 MID1 TMF1

6.43e-06193160706b65110db974f4ef90d3511ff34428976a52c9c
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 MBNL1 USP24 CHD9 CEP350 MID1 TMF1

6.43e-0619316079c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellClub_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

GABRP DSC2 TNFSF10 MUC16 SLC5A5 ZFP36L1 ADGRF1

6.43e-0619316076582c0367052b9d10fb629c383ee0c55872afd2d
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 MBNL1 USP24 CHD9 CEP350 MID1 TMF1

6.43e-061931607a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 GABRP FRAS1 AP1S3 VCAN ADGRF1 EPB41L1

6.43e-061931607263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 GABRP FRAS1 AP1S3 VCAN ADGRF1 EPB41L1

6.43e-06193160780e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 GABRP FRAS1 AP1S3 VCAN ADGRF1 EPB41L1

6.43e-061931607b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 MBNL1 USP24 CHD9 CEP350 MID1 TMF1

6.43e-061931607b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellRA|World / Chamber and Cluster_Paper

FRAS1 HIVEP2 AKAP12 COL24A1 VCAN MID1 NAV2

6.65e-06194160708f0afbb68a63150fbe107a5337299081c3f69e4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GABRP USP24 ABCA10 CLCN5 SCN2A UNC13C WNK4

6.87e-061951607a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FMO4 MAP1A PCLO TIAM2 RYR3 COL24A1

6.98e-0612816062cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

MAP1A CCDC30 MUC16 DNAH7 PTPRT DNAI4 IK

7.11e-061961607de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 ARHGEF28 SORT1 SCN2A UNC13C ADGRF1 EPB41L1

7.11e-061961607c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GABRP NCKAP1 MUC16 ITGB4 AKAP12 KIAA1217 ADGRF1

7.11e-0619616073e99a367b7d817e1f1221450fcec20ad7a7c7a2a
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GABRP NCKAP1 MUC16 ITGB4 AKAP12 KIAA1217 ADGRF1

7.11e-0619616071efacc37bbfbd05b5d4db3dd10f6d9a238d23e31
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 ARHGEF28 PCLO DNAH7 BICDL1 CLCN5 EPB41L1

7.11e-061961607eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 FRAS1 AP1S3 TNFSF10 DNAH7 SCN2A EPB41L1

7.35e-0619716077e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellSevere_COVID-19-Epithelial-transitional_Epi|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

GABRP NCKAP1 MUC16 ITGB4 AKAP12 KIAA1217 ADGRF1

7.35e-0619716075ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GABRP NCKAP1 MUC16 ITGB4 AKAP12 KIAA1217 ADGRF1

7.35e-06197160708b371309cd790b171ed76cabc7d910e71cd2835
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

GABRP NCKAP1 MUC16 ITGB4 AKAP12 KIAA1217 ADGRF1

7.35e-0619716079f49feee38647bbf964974aac96fa75602186b5c
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HIVEP2 PCLO TMEM132B NRXN3 SCN1A SCN2A SCN8A

7.59e-061981607c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellAT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

NCKAP1 MFSD2A BICDL1 ZFP36L1 SCN1A SDC4 CNR1

7.59e-061981607893036558a9ad86b57f9e735df35812e9d18739e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

USP24 PTPRT SCN1A KIAA1217 VCAN SCN2A TNR

7.85e-06199160719a97e27a4758e794ce7246d295e112b47931a48
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PCLO HECTD4 ADD2 MADD NRXN3 SCN2A AKAP11

7.85e-061991607f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCellNS-control-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NCKAP1 TNFSF10 MUC16 ITGB4 KIAA1217 ADGRF1 SDC4

8.11e-062001607d014959891893b6d3854a471fba1dc50c6625a0a
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA10 ADGRG4 AKAP12 VCAN NAV2 MME EPB41L2

8.11e-0620016073dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD8-positive,_alpha-beta_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NCKAP1 MUC16 ZBED4 DNAI4 ANKRD28 AKAP11

9.88e-0613616069d7080f695de4ef183e3dbdc18ba464a3b8e3469
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

PECAM1 MUC16 ADGRG4 PTPRT NRXN3 OR6Y1

1.12e-05139160664c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ADCY1 ZNF711 COL24A1 ADGRF1 WNK4

1.26e-051421606759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellPBMC-Control-cDC_2|Control / Compartment, Disease Groups and Clusters

MUC16 SLC5A5 NRXN3 GZMH SCN8A DNAAF6

1.93e-0515316064ee37266b0054f276c7a73ab9220f681b9d74c71
ToppCellPBMC-Mild-cDC_3|Mild / Compartment, Disease Groups and Clusters

KIAA1549 ADCY1 FAN1 KIAA1217 DNAAF6 MME

2.31e-0515816065fefab4831687cd8dd45f5cc84f681398069c3be
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZBTB20 ADAMTS5 SLC5A5 UNC13C MME GRIN3A

2.48e-051601606dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZBTB20 DSC2 SLC5A5 UNC13C MME GRIN3A

2.57e-051611606bf70be1de418615b5442ec684552551edaf1f072
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FRAS1 AP1S3 KCNB2 TIAM2 SORT1 SCN2A

2.57e-051611606ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AP1S3 RYR3 PARP4 BICDL1 RIMKLB VCAN

2.85e-0516416061cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellBasal_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

EPHB2 NRG1 FRAS1 DSC2 ITGB4 UNC13C

3.06e-051661606aea2ae12e4746149ebc6da063ef694381c098f80
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

CCDC30 MUC16 DNAH7 DNAI4 DNAAF6 ADGRF1

3.16e-05167160626cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAGLB FRAS1 MUC16 ADAMTS5 BICDL1 UNC13C

3.16e-0516716067abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAGLB FRAS1 MUC16 ADAMTS5 BICDL1 UNC13C

3.16e-051671606d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCellFetal_29-31_weeks-Epithelial-basal_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NRG1 FRAS1 ITGB4 NRXN3 KIAA1217 ADGRF1

3.27e-0516816066521bead9789d626b86cbd08692c621c5a5aef33
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRG1 FRAS1 ARHGEF28 DNAH7 AKAP12 EPB41L1

3.27e-051681606a086c306be430adf0632ba53e98cd8014d2de330
ToppCellFetal_29-31_weeks-Epithelial-basal_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NRG1 FRAS1 ITGB4 NRXN3 KIAA1217 ADGRF1

3.38e-051691606c3ee781735a9288ce1822b230d39bb91c1415589
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATMIN MIA3 ARHGEF28 TNFSF10 DOCK8 USP42

3.49e-05170160607b561cd9c528bc8444c9385e1de621eee7b697e
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP1A ADAMTS5 RYR3 VCAN MYPN GRIN3A

3.61e-05171160682de2885c8ce4fb7776da6a0207b3355c0910121
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP1A ADAMTS5 RYR3 VCAN MYPN GRIN3A

3.61e-05171160609e653973962fb884878089d281f0947f7a285f6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 NRG1 AP1S3 TNFSF10 BICDL1 SDC4

3.73e-0517216060c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRG1 LNX2 SLC22A24 MID1 UNC13C GRIN3A

3.73e-05172160692e76cbf4807704790f42cf2507e92f85cd3bc92
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 NRG1 AP1S3 TNFSF10 BICDL1 SDC4

3.73e-051721606eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell3'_v3-blood-Mast|blood / Manually curated celltypes from each tissue

AP1S3 KIAA1549 AKAP12 RYR3 UNC13C MME

3.73e-051721606e7a46bbeff749ca59b9f1357409ce1ad59dd22dd
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 PCLO RYR3 NRXN3 ZFP36L1 SDC4

3.85e-05173160666f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 PCLO RYR3 NRXN3 ZFP36L1 SDC4

3.85e-051731606649b08a409095592cccf31883be69c754411280d
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 PCLO KIAA1549 PTPRT AKAP11 DOP1A

3.98e-051741606f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRG1 KIAA1549 KCNB2 PTPRT UNC13C MME

3.98e-051741606b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRG1 LNX2 SLC22A24 MID1 UNC13C GRIN3A

3.98e-0517416062947e5906b172d149412fa4e77476fce4ea695d2
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRG1 LNX2 KCNB2 SLC22A24 PTPRT UNC13C

4.10e-05175160606af6629766e2054e6995e8cdb3907658fec49d3
ToppCellCiliated_cells-A-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

AKAP6 MAP1A CCDC30 DNAH7 NPAP1 DNAI4

4.24e-0517616061c364155f46b9a7c995bdc2cc2333c437cd90f5b
DiseaseIntellectual Disability

AKAP6 HIVEP2 DOCK8 ZMYM2 PDHX MFSD2A NRXN2 SCN1A SCN8A ATIC VPS53 EPB41L1

5.66e-0644715812C3714756
DiseaseNeurodevelopmental Disorders

NCKAP1 DOCK8 DHX30 SCN1A SCN2A SCN8A

1.11e-05931586C1535926
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A SCN8A

1.76e-05101583DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A SCN8A

1.76e-05101583DOID:0080422 (implicated_via_orthology)
Diseasefocal epilepsy (implicated_via_orthology)

DEPDC5 CNR1

2.85e-0521582DOID:2234 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A SCN8A

3.20e-05121583DOID:0060170 (implicated_via_orthology)
Diseasecoronary aneurysm

COL24A1 NRXN3 NAV2 GRIN3A

3.64e-05351584EFO_1000881
DiseaseSchizoaffective disorder-bipolar type

PCLO NRXN3 RAD21

8.01e-05161583EFO_0009965
DiseaseBenign familial infantile epilepsy

SCN2A SCN8A

8.52e-0531582cv:C5575231
DiseaseDent disease (implicated_via_orthology)

CLCN4 CLCN5

8.52e-0531582DOID:0050699 (implicated_via_orthology)
Diseasemyotonic disease (implicated_via_orthology)

MBNL1 MBNL3

8.52e-0531582DOID:450 (implicated_via_orthology)
Diseasethyroxine measurement, triiodothyronine measurement

EPHB2 TIAM2 ABCB9

9.69e-05171583EFO_0005130, EFO_0008392
DiseaseProfound Mental Retardation

DOCK8 ZMYM2 PDHX MFSD2A SCN1A SCN8A

1.07e-041391586C0020796
DiseaseMental Retardation, Psychosocial

DOCK8 ZMYM2 PDHX MFSD2A SCN1A SCN8A

1.07e-041391586C0025363
DiseaseMental deficiency

DOCK8 ZMYM2 PDHX MFSD2A SCN1A SCN8A

1.07e-041391586C0917816
Diseasehair colour measurement

NRG1 FRAS1 ZBTB17 MBNL1 AKAP12 THADA ZFP36L1 POC1B FES UNC13C EPB41L1 EPB41L2

1.26e-0461515812EFO_0007822
Diseasecleft lip

AKAP6 ARHGEF28 MUC16 THADA SLC13A1 ZFP36L1 ABCC10 MGAM2

1.55e-042841588EFO_0003959
Diseaseosteoarthritis (biomarker_via_orthology)

TNFSF10 PECAM1 ADAMTS5

1.87e-04211583DOID:8398 (biomarker_via_orthology)
Diseaseapolipoprotein A 1 measurement

DAGLB XIRP1 ARHGEF28 MAP1A MBNL1 MADD ABCB9 ZFP36L1 MUC17 FES ANKRD28 PLCB3 CNOT1 VPS53

1.98e-0484815814EFO_0004614
DiseaseEtat Marbre

NRG1 SCN1A CNR1

2.47e-04231583C0266487
Diseaseepilepsy (implicated_via_orthology)

SLC13A1 SCN1A SCN2A SCN8A UNC13C DEPDC5

2.55e-041631586DOID:1826 (implicated_via_orthology)
Diseasemyotonic dystrophy type 2 (implicated_via_orthology)

MBNL1 MBNL3

2.82e-0451582DOID:0050759 (implicated_via_orthology)
Diseaseprostate carcinoma, type 2 diabetes mellitus

AKAP6 MBNL1 THADA OSBPL7

2.86e-04591584EFO_0001663, MONDO_0005148
Diseaseinflammatory bowel disease (implicated_via_orthology)

NFIL3 EPB41L1 EPB41L2

3.18e-04251583DOID:0050589 (implicated_via_orthology)
DiseaseCoronary Arteriosclerosis

MIA3 PECAM1 HECTD4 SORT1

4.16e-04651584C0010054
DiseaseCoronary Artery Disease

MIA3 PECAM1 HECTD4 SORT1

4.16e-04651584C1956346
Diseasemyotonic dystrophy type 1 (implicated_via_orthology)

MBNL1 MBNL3

4.21e-0461582DOID:11722 (implicated_via_orthology)
DiseaseFamilial benign neonatal epilepsy

SCN2A SCN8A

4.21e-0461582C0220669
DiseaseMovement Disorders

NRG1 SCN1A CNR1

4.97e-04291583C0026650
Diseasecongenital heart disease (implicated_via_orthology)

CHD9 RNF40 USP42 SON

5.22e-04691584DOID:1682 (implicated_via_orthology)
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

5.88e-0471582C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

5.88e-0471582C0751057
DiseaseGoiter

SLC5A5 CLCN5

5.88e-0471582C0018021
Diseaseosteopetrosis (implicated_via_orthology)

CLCN4 CLCN5

5.88e-0471582DOID:13533 (implicated_via_orthology)
Diseaseneuropsychological test

KCNB2 BICDL1 NRXN3 KIAA1217 AEBP2 UNC13C

6.95e-041971586EFO_0003926
DiseaseAttached earlobe

HIVEP2 KIAA1217

7.81e-0481582HP_0009907
DiseaseS-6-hydroxywarfarin measurement

LNX2 PCLO CHD9 BTAF1 KCNB2 TIAM2 NAV2 GRIN3A

8.63e-043681588EFO_0803326
DiseaseFebrile Convulsions

SCN1A SCN2A

1.00e-0391582C0009952
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A

1.00e-0391582C3502809
Diseaseamino acid measurement

EPHB2 OR2F2 ARHGEF28 OR2F1 DNAH7 RYR3 COL24A1 VCAN MCM9 UNC13C MGAM2

1.11e-0367815811EFO_0005134
Diseasecreativity measurement

NRG1 EPB41L2

1.25e-03101582EFO_0010650
Diseaseautism spectrum disorder (implicated_via_orthology)

CHD9 NRXN3 NRXN2 SCN1A SCN2A

1.39e-031521585DOID:0060041 (implicated_via_orthology)
Diseasenevus count, cutaneous melanoma

MIA3 DOCK8 AKAP12 ZFP36L1

1.47e-03911584EFO_0000389, EFO_0004632
Diseasefibrinogen measurement, tissue plasminogen activator measurement

HECTD4 CHD9 ZFP36L1

1.81e-03451583EFO_0004623, EFO_0004791
DiseaseMalignant neoplasm of salivary gland

ITGB4 VCAN SON

1.81e-03451583C0220636
DiseaseMalignant neoplasm of breast

AKAP6 GABRP NRG1 XIRP1 RARG TNFSF10 FRMPD1 DVL3 RECQL AKAP12 SLC5A5 MME FASTKD3 DOP1A

1.97e-03107415814C0006142
DiseaseSalivary Gland Neoplasms

ITGB4 VCAN SON

2.06e-03471583C0036095
DiseaseCardiotoxicity

NRG1 RARG

2.14e-03131582C0876994
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A

2.14e-03131582C0751122
DiseaseMental Retardation, X-Linked Nonsyndromic

ZNF711 CLCN4

2.14e-03131582C3501611
Diseaseocular hypertension, response to triamcinolone acetonide

CHD9 ITGB4 COL24A1

2.32e-03491583EFO_0006954, EFO_1001069
Diseasetyrosine measurement

NRG1 AP1G1 ZFP36L1 DEPDC5

2.40e-031041584EFO_0005058
Diseasegamma-glutamylglutamate measurement

EIF2AK4 ABCC10

2.49e-03141582EFO_0021137
Diseasegallstones

DAGLB AP1S3 POC1B NUP153

2.75e-031081584EFO_0004210
DiseaseMMR-related febrile seizures

SCN1A SCN2A

2.86e-03151582EFO_0006519
Diseaseunipolar depression, cognitive function measurement

ADAMTS5 PTAR1

2.86e-03151582EFO_0003761, EFO_0008354
Diseasesevere acute respiratory syndrome, COVID-19

EPHB2 ARHGEF28 COL24A1 CLCN5 KIAA1217 AEBP2 UNC13C TNR

2.91e-034471588EFO_0000694, MONDO_0100096
DiseaseIschemic stroke, fibrinogen measurement

HECTD4 CHD9 ZFP36L1

3.22e-03551583EFO_0004623, HP_0002140
DiseasePontoneocerebellar hypoplasia

PCLO VPS53

3.25e-03161582cv:C1261175
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

3.25e-03161582C0393706
Diseasetestosterone measurement

DAGLB MIA3 ZBTB20 MAP1A TNFSF10 MBNL1 WDR81 SLC22A24 THADA GTF3C2 ZFP36L1 MYPN MCM9 MME ABCC10

3.62e-03127515815EFO_0004908
DiseaseCannabis Dependence

NRG1 CNR1

3.68e-03171582C0006870
DiseaseAstrocytosis

ITGB4 TNR

3.68e-03171582C3887640
DiseaseGliosis

ITGB4 TNR

3.68e-03171582C0017639
Diseasebalding measurement

ZBTB20 DOCK8 MBNL1 AKAP12 COL24A1 THADA GTF3C1 OSBPL7 FES RIC1 EPB41L2

3.70e-0379215811EFO_0007825
Diseaseresponse to platinum based chemotherapy

ADCY1 NRXN3

4.12e-03181582EFO_0004647
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

4.12e-03181582HP_0002373
Diseasecoronary artery disease

DAGLB MIA3 HIVEP2 ZBTB20 CCDC30 DOCK8 PECAM1 HECTD4 KCNB2 AKAP12 THADA KIAA1217 FES ABCC10

5.04e-03119415814EFO_0001645
Diseasesystolic blood pressure, alcohol drinking

HECTD4 POC1B FES ABCC10

5.05e-031281584EFO_0004329, EFO_0006335
Diseasetea consumption measurement

MIA3 HECTD4 KCNB2 NRXN3

5.19e-031291584EFO_0010091
Diseaseparental longevity

PCLO HECTD4 RYR3 CEP350 FES TMF1 PHLPP1 ANKRD28

5.29e-034941588EFO_0007796

Protein segments in the cluster

PeptideGeneStartEntry
TSAETKVLEMETTVE

RNF40

266

O75150
SEDSISSTIMDVDST

AEBP2

221

Q6ZN18
ITQLMEETTTEKTSL

VCAN

1161

P13611
SIATTHLMDQSVTEV

VCAN

2781

P13611
ISAAVLNMEESVTIS

EIF2AK4

1381

Q9P2K8
EVTTNHSVMEELTSV

ABCA10

101

Q8WWZ4
VSNSTMEDVISIADN

ADGRF1

366

Q5T601
STTINVPTSNEMETE

ADGRG4

1896

Q8IZF6
ATLSSTESTASEMQE

AKAP12

641

Q02952
AEETTEMVSAVSQLT

AKAP12

996

Q02952
ETATEMLTSELQTQA

AKAP12

1566

Q02952
TSKEIISSEMLATSI

AFTPH

111

Q6ULP2
MISTSETIIDINGTV

ADAMTS5

791

Q9UNA0
ITRESASEMISTIEA

CEACAM20

351

Q6UY09
ASEMISTIEAELNSS

CEACAM20

356

Q6UY09
SMSTLATTLQEVLLT

GZMH

151

P20718
TVEMLVSSASAELTL

ANKRD28

871

O15084
HTIVNETLESMTSLE

AKAP11

881

Q9UKA4
ESLATETMTAAVTNV

AKAP11

1686

Q9UKA4
LMVEAVSTSVQDSSV

DOP1A

226

Q5JWR5
VESASVTSQLEIEAM

DOP1A

1166

Q5JWR5
VLTQDSMTVEDVETL

CLCN4

611

P51793
ASTIDASVTSNEIEM

CEP76

516

Q8TAP6
TIDVTDFLSMTQQDS

DHX30

201

Q7L2E3
SSITDSTMSLNIITV

DVL3

236

Q92997
STSLLSEIEQSMEAE

BICDL1

341

Q6ZP65
QTTTDMTERLSAEQI

CALML6

21

Q8TD86
NDQSFEVTMTATTEV

DMTF1

81

Q9Y222
VTDSTMSLNIITVTL

DVL2

256

O14641
SAMSTATVTVNVEDQ

DSC2

451

Q02487
LSVETQSTSSEEMVP

RARG

61

P13631
DMLVSTTTSNLLLES

RAD21

181

O60216
STLSLTQSELEHISM

RIC1

1236

Q4ADV7
ESILSESHSVIVMSS

NRG1

361

Q02297
SLSAETMIEVLISDV

PCDHB1

431

Q9Y5F3
LEESSISLMSSVVAD

KIAA1549

456

Q9HCM3
STESFIMEDVVDSSL

ARHGEF28

801

Q8N1W1
TVITIQASNSTELDM

AP1G1

731

O43747
EDSDMLQEVSTVSQT

AP1S3

136

Q96PC3
LTSSSTLTEILEAMK

DEPDC5

1171

O75140
ISSMSTEQTLASDTD

MAPK9

396

P45984
LSTSLTEEMASTDLD

MUC16

1461

Q8WXI7
SDLINTSIASSTMDV

MUC16

2371

Q8WXI7
VTAMSEITTNRLTAT

MUC16

2826

Q8WXI7
MNSVSEDTIKEVTSS

MUC16

3886

Q8WXI7
VVTTSTREQAIVSMS

MUC16

3981

Q8WXI7
SSEITRIEMESTFSL

MUC16

6641

Q8WXI7
SVLTESAKMTITTQT

MUC16

7611

Q8WXI7
TMETEAIQLSENTAV

MUC16

8926

Q8WXI7
SSEITRIEMESTSTL

MUC16

8986

Q8WXI7
STMSQDISTEVITRL

MUC16

9051

Q8WXI7
VTTDTEKLEMTNVVT

MUC16

9216

Q8WXI7
METSISEETSSATEK

MUC16

9291

Q8WXI7
MSLDISDEVVTRLST

MUC16

9636

Q8WXI7
LVSSFTQTEAMLVSV

ABCC10

1201

Q5T3U5
SITTETISTTMENSL

EPB41L1

746

Q9H4G0
EDSMEISVTDGLTVT

FRAS1

1681

Q86XX4
LVLASSSTVVMQDES

MAP1A

2781

P78559
VMIRSSSQDSEVSTV

MADD

1186

Q8WXG6
LDTKSTMVIDATVTT

MGAM2

2346

Q2M2H8
DEMVSVEQTSSSSLN

LNX2

6

Q8N448
EMVTISDASQRTEIS

EPB41L2

876

O43491
ESVSVVTVMRDSSES

HMGXB3

261

Q12766
LAAVEETLMDSTTAT

EPHB2

16

P29323
ISASLQTITMESLTA

PCLO

3161

Q9Y6V0
QTITMESLTAETIDS

PCLO

3166

Q9Y6V0
LITVTMSSDSRVVDD

PDHX

466

O00330
MQTSESTKSELVTVT

PECAM1

216

P16284
MVLNSALTEVSEDST

NFIL3

26

Q16649
ITMKTSVIEFTETSA

FMO4

296

P31512
MSTVNISITNEEDVV

MME

331

P08473
ETTATTLLADMATTI

NRXN2

1351

Q9P2S2
LTIIETTKDSLSMTS

NRXN3

1371

Q9Y4C0
SVNTVDEENTVMVAS

MPHOSPH9

396

Q99550
DEENTVMVASASVSQ

MPHOSPH9

401

Q99550
SSDVQEMILSSATAD

GCN1

2506

Q92616
IAETIMASSNESLVV

TMPO

281

P42167
VMDILSFDSTTTTET

POC1B

361

Q8TC44
ETVVTTDLLTQAMTE

PRDM10

891

Q9NQV6
DTSSNEVTIMVSSIV

OR2F1

191

Q13607
DTSSNEAAIMVSSIV

OR2F2

191

O95006
SSTLSQEVSDLVEMI

PARP4

256

Q9UKK3
EFRTMVSTTELQKTT

PARP4

1106

Q9UKK3
MSTEEILTVSVVNQS

HECTD4

3206

Q9Y4D8
SIVVMESSFQITEET

ITGB4

76

P16144
VDSLVEMLVETSDLS

NCKAP1

526

Q9Y2A7
LSSDADVTVSILTMN

GRIN3A

246

Q8TCU5
TDTPLNETDTTITVM

PTPRT

596

O14522
LTMFISTEQTERDSA

MFSD2A

181

Q8NA29
SSEVNATEEMSTLVN

PLCB3

581

Q01970
LDMIDTITSVAEATE

ADCY1

376

Q08828
TITSVAEATEVDLNM

ADCY1

381

Q08828
NIQTQTEESELSTMT

ATMIN

646

O43313
TEESELSTMTTEPVL

ATMIN

651

O43313
EESMSSVETRTLIKS

CHD9

2061

Q3L8U1
TEVIVDMKSTSSIDS

KCNB2

591

Q92953
FMDDITTIVNVVTSE

DOCK8

1016

Q8NF50
LELDDLTASTNSIMT

BTAF1

481

O14981
TMSLQDVLTDLSAES

DAGLB

376

Q8NCG7
ETMETKSVIDSRVSS

FRMPD1

926

Q5SYB0
TVLTQDSMTVEDVET

CLCN5

666

P51795
MSTDLEEVVSSILNV

DNAH7

3816

Q8WXX0
METTISDILESEVVN

CCDC30

691

Q5VVM6
LSMTQSETTSDQSDI

CEP350

2036

Q5VT06
NLIDTTTSMHSVEVS

DDX12P

416

Q92771
IAKVTMSVSTDTSAE

CNR1

456

P21554
ADSTMIDTNDNTVTV

MBNL1

206

Q9NR56
TDASMIEASDNTVTI

MBNL3

201

Q9NUK0
STTEKNSETSSLMDI

DNAI4

361

Q5VTH9
TEQATVTMVSSEDIE

E4F1

746

Q66K89
MESQNVDFESVSSVT

DNAAF6

16

Q9NQM4
MEEPELTLISTTDTS

CEP295

2396

Q9C0D2
LTLISTTDTSIAEMD

CEP295

2401

Q9C0D2
ESEDVSNKVSMSSTV

SDC4

121

P31431
ISSLMVTSLTEVASN

SLC13A1

476

Q9BZW2
SVALVDMVDSNTTLE

SLC17A5

61

Q9NRA2
TEKQTEVETVMSEVS

BYSL

156

Q13895
TLDIASISSISESNM

GABRP

66

O00591
LEEEGTETAQMLTVT

LRRC72

271

A6NJI9
KIMTSDEVSETSTLV

PRR14L

236

Q5THK1
SCTSEITTSLSEEML

OSBPL7

426

Q9BZF2
VSTMLVVSSEDSTLS

MUC17

3171

Q685J3
TSVTDELAVATEMVF

FES

311

P07332
DTVTLEDAITVVSVM

MCM9

586

Q9NXL9
SVMQALESLTETQVS

MIDN

116

Q504T8
NSNVSMVDLTSVTLE

FAN1

81

Q9Y2M0
TSVLSEDNSIQTMIT

SORT1

416

Q99523
SEEAMQSLVTSSRTI

BNIP1

156

Q12981
DAATETVTTAMSQEN

THADA

1746

Q6YHU6
SVSNSSVILENTMED

PPP4R1

371

Q8TF05
SLISQTVIDSSVMEQ

PTAR1

246

Q7Z6K3
DSMSELVVSEIFVSQ

TMEM132B

401

Q14DG7
TVSSLDEMVVSVQAN

TMEM132B

726

Q14DG7
TEETLTTELVRSTMK

SLC22A24

311

Q8N4F4
ETSMILDSEKTSETA

MIA3

781

Q5JRA6
AVQMSVEESLTDTQL

SEC24A

786

O95486
TIIETTKDSLSMTSE

NRXN3

366

Q9HDB5
SSEEVLSFISTMETL

FASTKD3

111

Q14CZ7
TLETTFDTNVTTEMS

NAV2

776

Q8IVL1
MITETTVQVLSSGEV

KIAA1217

1386

Q5T5P2
IEMLQSEETSSTSQL

IARS2

916

Q9NSE4
ILEDKTETMTNSSIT

NPAP1

381

Q9NZP6
MTTIILEVDNHTVTT

OR6Y1

1

Q8NGX8
ENSITEKTDLTMSTA

SCN1A

1966

P35498
ISRLTSDTTMVSDLV

ABCB9

286

Q9NP78
IVSEGDTETTTNSEM

AKAP6

1366

Q13023
LSQMTTSADTDVDTS

ADD2

666

P35612
SVSQELSETILTMVA

CNOT1

661

A5YKK6
EMITEEDTQTNFSLS

COL24A1

336

Q17RW2
MASVSALTEELDSIT

RECQL

1

P46063
IDVKTTMESISNTST

TMF1

201

P82094
MTTTLVSATIFDLSE

ZFP36L1

1

Q07352
MNDSIVSTSDIRSVL

USP42

386

Q9H9J4
SMDFSTVVSEEDLVT

RBP3

356

P10745
QTETENTETVDSGMS

UNC13C

616

Q8NB66
LEMSRTNTENIETST

TIAM2

466

Q8IVF5
STSINAMAAVTVEDL

SLC5A5

356

Q92911
VDTLVESSTNVEMIL

RYR3

3896

Q15413
TERVSMATASSQVLI

MID1

336

O15344
SIASILTNTMEELEE

SCN2A

706

Q99250
DLMVTASSETSISLI

TNR

691

Q92752
MSVVTNTLVEELEES

SCN8A

701

Q9UQD0
MEAQTTLTTNDIVIS

IK

266

Q13123
MSLLSVVSTASETSE

RIMKLB

316

Q9ULI2
RALTLTVVSESAETM

NUP153

756

P49790
TEMQSSESKDTSLET

ATIC

156

P31939
ELMTEISTGVETTAN

RALGAPB

1361

Q86X10
MDTFSTVISSSIQLL

VPS53

591

Q5VIR6
SNEVEMDSTVITVSN

ZBTB20

436

Q9HC78
VSSDALDTELLTMTD

ZMYM2

941

Q9UBW7
GSEVSVVTVDDMVTL

ZBTB17

651

Q13105
RVAIQTMEVSDFTST

USP24

1316

Q9UPU5
EISSELSTSEMSSEV

PHLPP1

1476

O60346
VKTSSEMTSAEASVE

GTF3C2

36

Q8WUA4
MNTDVLQDTVSSVTA

ZMYM1

361

Q5SVZ6
MILRTSEETISTVQE

TNFSF10

91

P50591
ELLTTVSLASMQEES

GTF3C1

451

Q12789
TMVSEEVLVTNSDTE

ZNF711

156

Q9Y462
LELGVSMTSVDDTET

HIVEP2

1856

P31629
TVLMSSTTVTEQAEP

XIRP1

1781

Q702N8
ATETTVLMSQTEADL

WNK4

6

Q96J92
TSELSTMTVSQSLEV

SON

661

P18583
SLTTQDTEHDMVIST

SON

1631

P18583
LTLSDTVLSMETVVA

WDR81

1181

Q562E7
SVSVVSSEEISSDMS

ZBED4

226

O75132
TVRTQETDVVEMTTQ

GARIN5B

591

Q8N5Q1
MQDDSIEASTSISQL

MYPN

1

Q86TC9