Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoxidoreductase activity

NQO2 POR CYP27C1 CYP21A2 BCO1 DNAJC10

1.03e-04766216GO:0016491
GeneOntologyMolecularFunctioncysteine-type endopeptidase inhibitor activity involved in apoptotic process

BIRC2 BIRC3

2.87e-0424212GO:0043027
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

POR CYP27C1 CYP21A2

1.06e-03194213GO:0016705
GeneOntologyMolecularFunctioncysteine-type endopeptidase regulator activity involved in apoptotic process

BIRC2 BIRC3

1.46e-0354212GO:0043028
GeneOntologyMolecularFunctionflavin adenine dinucleotide binding

NQO2 POR

4.34e-0394212GO:0050660
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H

NQO2 POR

4.43e-0395212GO:0016651
GeneOntologyMolecularFunctiondioxygenase activity

POR BCO1

4.71e-0398212GO:0051213
GeneOntologyMolecularFunctionmonooxygenase activity

CYP27C1 CYP21A2

6.43e-03115212GO:0004497
GeneOntologyMolecularFunctionubiquitin protein ligase activity

BIRC2 BIRC3 TRIM48

6.65e-03372213GO:0061630
GeneOntologyMolecularFunctiontransition metal ion binding

NQO2 BIRC2 CYP27C1 CYP21A2 TRIM48

6.78e-031189215GO:0046914
GeneOntologyMolecularFunctionelectron transfer activity

NQO2 POR

7.44e-03124212GO:0009055
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

BIRC2 BIRC3 TRIM48

8.01e-03398213GO:0061659
GeneOntologyMolecularFunctionheme binding

CYP27C1 CYP21A2

1.13e-02154212GO:0020037
GeneOntologyMolecularFunctioncarboxylic ester hydrolase activity

NDST3 ABHD16A

1.17e-02157212GO:0052689
GeneOntologyMolecularFunctionprotein-folding chaperone binding

BIRC2 DNAJC10

1.23e-02161212GO:0051087
GeneOntologyMolecularFunctiontetrapyrrole binding

CYP27C1 CYP21A2

1.27e-02164212GO:0046906
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

BIRC2 BIRC3 TRIM48

1.28e-02473213GO:0004842
GeneOntologyMolecularFunctioniron ion binding

CYP27C1 CYP21A2

1.30e-02166212GO:0005506
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

BIRC2 BIRC3 TRIM48

1.58e-02512213GO:0019787
GeneOntologyMolecularFunctionextracellular matrix structural constituent

MUC5AC TINAG

1.65e-02188212GO:0005201
GeneOntologyMolecularFunctionaminoacyltransferase activity

BIRC2 BIRC3 TRIM48

1.75e-02532213GO:0016755
GeneOntologyBiologicalProcessregulation of hormone levels

POR CYP27C1 CHD7 CYP21A2 GALR1 BCO1

4.61e-05684216GO:0010817
GeneOntologyBiologicalProcessregulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

BIRC2 BIRC3

1.17e-0416212GO:0070424
GeneOntologyBiologicalProcesshormone metabolic process

POR CYP27C1 CYP21A2 BCO1

1.80e-04286214GO:0042445
GeneOntologyBiologicalProcesspositive regulation of protein polyubiquitination

BIRC2 BIRC3

1.86e-0420212GO:1902916
GeneOntologyBiologicalProcessregulation of RIG-I signaling pathway

BIRC2 BIRC3

2.05e-0421212GO:0039535
GeneOntologyBiologicalProcessretinal metabolic process

CYP27C1 BCO1

2.05e-0421212GO:0042574
GeneOntologyBiologicalProcessnegative regulation of necroptotic process

BIRC2 BIRC3

2.69e-0424212GO:0060546
GeneOntologyBiologicalProcessnegative regulation of programmed necrotic cell death

BIRC2 BIRC3

3.16e-0426212GO:0062099
GeneOntologyBiologicalProcessRIG-I signaling pathway

BIRC2 BIRC3

4.22e-0430212GO:0039529
GeneOntologyBiologicalProcessnucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

BIRC2 BIRC3

4.22e-0430212GO:0035872
GeneOntologyBiologicalProcessregulation of protein polyubiquitination

BIRC2 BIRC3

4.81e-0432212GO:1902914
GeneOntologyBiologicalProcessregulation of necroptotic process

BIRC2 BIRC3

6.44e-0437212GO:0060544
GeneOntologyBiologicalProcessregulation of toll-like receptor signaling pathway

BIRC2 BIRC3

7.52e-0440212GO:0034121
GeneOntologyBiologicalProcessolefinic compound metabolic process

CYP27C1 CYP21A2 BCO1

7.74e-04180213GO:0120254
GeneOntologyBiologicalProcessregulation of programmed necrotic cell death

BIRC2 BIRC3

8.69e-0443212GO:0062098
GeneOntologyBiologicalProcessregulation of reactive oxygen species metabolic process

NQO2 BIRC2 BIRC3

8.78e-04188213GO:2000377
GeneOntologyBiologicalProcessnecroptotic process

BIRC2 BIRC3

1.32e-0353212GO:0070266
GeneOntologyBiologicalProcessretinol metabolic process

CYP27C1 BCO1

1.32e-0353212GO:0042572
MousePhenoaorta coarctation

CHD7 BRD2

1.08e-0413172MP:0003387
MousePhenoabnormal common carotid artery morphology

CHD7 BRD2

1.08e-0413172MP:0012729
MousePhenointerrupted aortic arch, type b

CHD7 BRD2

1.65e-0416172MP:0011659
MousePhenoabnormal middle ear morphology

MUC5B CHD7 BRD2

1.75e-0492173MP:0000049
MousePhenoabnormal epithalamus morphology

CHD7 BRD2

2.35e-0419172MP:0000840
MousePhenoincreased circulating glucagon level

G6PC3 BRD2

2.61e-0420172MP:0002712
MousePhenoabnormal circulating cholesterol level

G6PC3 NDST3 POR CHD7 BRD2 BCO1

2.89e-04823176MP:0000180
MousePhenodecreased magnesium level

ABHD16A CHD7

3.17e-0422172MP:0031658
MousePhenodecreased circulating magnesium level

ABHD16A CHD7

3.17e-0422172MP:0010093
MousePhenoabnormal cholesterol level

G6PC3 NDST3 POR CHD7 BRD2 BCO1

3.83e-04867176MP:0003947
MousePhenoabnormal sterol level

G6PC3 NDST3 POR CHD7 BRD2 BCO1

4.15e-04880176MP:0012224
MousePhenoabnormal cardiac outflow tract development

POR CHD7 BRD2

5.31e-04134173MP:0006126
MousePhenoabnormal vagus nerve morphology

CHD7 BRD2

5.54e-0429172MP:0001074
MousePhenoabnormal secretory circumventricular organ morphology

CHD7 BRD2

5.54e-0429172MP:0013563
MousePhenoabnormal cholesterol homeostasis

G6PC3 NDST3 POR CHD7 BRD2 BCO1

5.78e-04936176MP:0005278
MousePhenodecreased leukocyte cell number

G6PC3 NDST3 BIRC2 BIRC3 CHD7 GALR1 BRD2

6.05e-041342177MP:0000221
MousePhenoincreased susceptibility to otitis media

MUC5B CHD7

6.34e-0431172MP:0001850
MousePhenoabnormal circumventricular organ morphology

CHD7 BRD2

6.34e-0431172MP:0013562
MousePhenoear inflammation

MUC5B CHD7

1.06e-0340172MP:0001849
MousePhenoabnormal circulating glucagon level

G6PC3 BRD2

1.06e-0340172MP:0002695
MousePhenoabnormal lymphocyte morphology

NQO2 NDST3 BIRC2 BIRC3 CHD7 GALR1 BRD2

1.11e-031483177MP:0002619
MousePhenointerrupted aortic arch

CHD7 BRD2

1.11e-0341172MP:0004157
MousePhenodecreased circulating cholesterol level

G6PC3 NDST3 POR CHD7

1.14e-03397174MP:0005179
MousePhenointerrupted aorta

CHD7 BRD2

1.22e-0343172MP:0010544
MousePhenoabnormal carotid artery morphology

CHD7 BRD2

1.28e-0344172MP:0004181
MousePhenoabnormal myocardium layer morphology

POR FHOD3 CHD7 BRD2

1.33e-03414174MP:0005329
MousePhenodecreased cholesterol level

G6PC3 NDST3 POR CHD7

1.38e-03418174MP:0003983
MousePhenodecreased sterol level

G6PC3 NDST3 POR CHD7

1.41e-03421174MP:0012225
MousePhenoabnormal heart layer morphology

POR FHOD3 CHD7 BRD2

1.43e-03422174MP:0010545
MousePhenoabnormal magnesium level

ABHD16A CHD7

1.58e-0349172MP:0020883
MousePhenoabnormal circulating magnesium level

ABHD16A CHD7

1.58e-0349172MP:0001771
MousePhenoabnormal magnesium ion homeostasis

ABHD16A CHD7

1.65e-0350172MP:0011979
MousePhenoabnormal immune serum protein physiology

BIRC2 MUC5AC BIRC3 ABHD16A MUC5B BRD2

1.83e-031165176MP:0002723
MousePhenoabnormal middle ear ossicle morphology

CHD7 BRD2

2.06e-0356172MP:0005105
MousePhenoabnormal subclavian artery morphology

CHD7 BRD2

2.06e-0356172MP:0003395
MousePhenodecreased body length

G6PC3 ABHD16A CHD7 DNAJC10

2.36e-03484174MP:0001258
MousePhenoabnormal fluid regulation

POR FHOD3 MUC5B CHD7 BRD2

2.42e-03826175MP:0001784
MousePhenoabnormal cardiac muscle tissue morphology

POR FHOD3 CHD7 BRD2

2.45e-03489174MP:0010630
MousePhenohepatic steatosis

POR BRD2 BCO1

2.58e-03232173MP:0002628
DomainWxxW_domain

MUC5AC MUC5B

1.80e-056212IPR025155
DomainMucin2_WxxW

MUC5AC MUC5B

1.80e-056212PF13330
DomainBIR

BIRC2 BIRC3

3.36e-058212SM00238
DomainBIR_REPEAT_2

BIRC2 BIRC3

3.36e-058212PS50143
Domain-

BIRC2 BIRC3

3.36e-0582121.10.1170.10
DomainBIR_rpt

BIRC2 BIRC3

3.36e-058212IPR001370
DomainBIR_REPEAT_1

BIRC2 BIRC3

3.36e-058212PS01282
DomainBIR

BIRC2 BIRC3

3.36e-058212PF00653
DomainFlavoprotein-like_dom

NQO2 POR

5.39e-0510212IPR029039
Domain-

NQO2 POR

5.39e-05102123.40.50.360
DomainTIL

MUC5AC MUC5B

7.89e-0512212PF01826
DomainC8

MUC5AC MUC5B

7.89e-0512212PF08742
DomainUnchr_dom_Cys-rich

MUC5AC MUC5B

9.32e-0513212IPR014853
DomainC8

MUC5AC MUC5B

9.32e-0513212SM00832
DomainTIL_dom

MUC5AC MUC5B

1.09e-0414212IPR002919
DomainGlyco_hormone_CN

MUC5AC MUC5B

1.25e-0415212IPR006208
DomainCys_knot

MUC5AC MUC5B

1.25e-0415212PF00007
DomainCARD

BIRC2 BIRC3

1.43e-0416212SM00114
DomainVWFD

MUC5AC MUC5B

1.43e-0416212PS51233
DomainVWD

MUC5AC MUC5B

1.43e-0416212SM00216
DomainVWF_type-D

MUC5AC MUC5B

1.43e-0416212IPR001846
DomainVWD

MUC5AC MUC5B

1.43e-0416212PF00094
DomainCTCK_1

MUC5AC MUC5B

1.82e-0418212PS01185
DomainVWC_out

MUC5AC MUC5B

2.04e-0419212SM00215
DomainCT

MUC5AC MUC5B

2.74e-0422212SM00041
DomainCys_knot_C

MUC5AC MUC5B

3.56e-0425212IPR006207
DomainCTCK_2

MUC5AC MUC5B

3.56e-0425212PS01225
DomainCARD

BIRC2 BIRC3

4.47e-0428212PF00619
DomainVWC

MUC5AC MUC5B

4.47e-0428212PF00093
DomainCARD

BIRC2 BIRC3

5.49e-0431212IPR001315
DomainCARD

BIRC2 BIRC3

6.23e-0433212PS50209
DomainVWFC_1

MUC5AC MUC5B

7.41e-0436212PS01208
DomainVWC

MUC5AC MUC5B

8.26e-0438212SM00214
DomainVWFC_2

MUC5AC MUC5B

8.26e-0438212PS50184
DomainVWF_dom

MUC5AC MUC5B

1.01e-0342212IPR001007
DomainCyt_P450_E_grp-I

CYP27C1 CYP21A2

1.16e-0345212IPR002401
DomainCyt_P450_CS

CYP27C1 CYP21A2

1.60e-0353212IPR017972
DomainCYTOCHROME_P450

CYP27C1 CYP21A2

1.85e-0357212PS00086
Domain-

CYP27C1 CYP21A2

1.92e-03582121.10.630.10
Domainp450

CYP27C1 CYP21A2

1.92e-0358212PF00067
DomainCyt_P450

CYP27C1 CYP21A2

2.05e-0360212IPR001128
DomainZF_RING_1

BIRC2 BIRC3 TRIM48

4.04e-03291213PS00518
DomainZF_RING_2

BIRC2 BIRC3 TRIM48

4.32e-03298213PS50089
DomainRING

BIRC2 BIRC3 TRIM48

4.61e-03305213SM00184
Domain-

BIRC2 BIRC3

4.84e-03932121.10.533.10
DomainDEATH-like_dom

BIRC2 BIRC3

5.47e-0399212IPR011029
DomainZnf_RING

BIRC2 BIRC3 TRIM48

5.55e-03326213IPR001841
Domain-

NDST3 N4BP2L2 EEF2 CHD7

8.78e-037462143.40.50.300
PathwayKEGG_MEDICUS_PATHOGEN_HSV_GD_TO_HVEM_NFKB_SIGNALING_PATHWAY

BIRC2 BIRC3

8.97e-0512172M47600
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC5AC MUC5B

1.63e-0416172M27410
PathwayWP_CLASSICAL_PATHWAY_OF_STEROIDOGENESIS_WITH_GLUCOCORTICOID_AND_MINERALOCORTICOID_METABOLISM

POR CYP21A2

1.63e-0416172M39815
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC5AC MUC5B

1.84e-0417172M27412
PathwayREACTOME_TNF_RECEPTOR_SUPERFAMILY_TNFSF_MEMBERS_MEDIATING_NON_CANONICAL_NF_KB_PATHWAY

BIRC2 BIRC3

1.84e-0417172M27561
PathwayREACTOME_DISEASES_OF_METABOLISM

G6PC3 MUC5AC MUC5B CYP21A2

1.92e-04250174M27554
PathwayREACTOME_TNF_RECEPTOR_SUPERFAMILY_TNFSF_MEMBERS_MEDIATING_NON_CANONICAL_NF_KB_PATHWAY

BIRC2 BIRC3

2.07e-0418172MM15275
PathwaySA_CASPASE_CASCADE

BIRC2 BIRC3

2.31e-0419172M7997
PathwayREACTOME_TICAM1_RIP1_MEDIATED_IKK_COMPLEX_RECRUITMENT

BIRC2 BIRC3

2.31e-0419172M27020
PathwayBIOCARTA_MITOCHONDRIA_PATHWAY

BIRC2 BIRC3

2.31e-0419172M16257
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

NQO2 POR CYP21A2

2.46e-04104173M738
PathwayBIOCARTA_MITOCHONDRIA_PATHWAY

BIRC2 BIRC3

2.84e-0421172MM1484
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC5AC MUC5B

2.84e-0421172MM15706
PathwayBIOCARTA_CASPASE_PATHWAY

BIRC2 BIRC3

3.12e-0422172M17902
PathwayREACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1

BIRC2 BIRC3

3.41e-0423172M1003
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC5AC MUC5B

3.41e-0423172M556
PathwayREACTOME_TNFR1_INDUCED_PROAPOPTOTIC_SIGNALING

BIRC2 BIRC3

3.41e-0423172MM15177
PathwayBIOCARTA_CASPASE_PATHWAY

BIRC2 BIRC3

4.04e-0425172MM1359
PathwayREACTOME_TNFR1_INDUCED_PROAPOPTOTIC_SIGNALING

BIRC2 BIRC3

4.04e-0425172M27435
PathwayREACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1

BIRC2 BIRC3

4.04e-0425172MM15646
PathwayREACTOME_DECTIN_2_FAMILY

MUC5AC MUC5B

4.37e-0426172M27483
PathwayBIOCARTA_DEATH_PATHWAY

BIRC2 BIRC3

5.45e-0429172M14971
PathwayPID_CD40_PATHWAY

BIRC2 BIRC3

6.24e-0431172M45
PathwayREACTOME_RIPK1_MEDIATED_REGULATED_NECROSIS

BIRC2 BIRC3

6.65e-0432172M29666
PathwayREACTOME_TNFR1_INDUCED_NF_KAPPA_B_SIGNALING_PATHWAY

BIRC2 BIRC3

7.07e-0433172M27438
PathwayREACTOME_TNFR1_INDUCED_NF_KAPPA_B_SIGNALING_PATHWAY

BIRC2 BIRC3

7.07e-0433172MM15180
PathwayREACTOME_NOD1_2_SIGNALING_PATHWAY

BIRC2 BIRC3

7.07e-0433172MM14663
PathwayWP_PHOTODYNAMIC_THERAPYINDUCED_NFKB_SURVIVAL_SIGNALING

BIRC2 BIRC3

7.96e-0435172M39529
PathwayREACTOME_RIPK1_MEDIATED_REGULATED_NECROSIS

BIRC2 BIRC3

7.96e-0435172MM15168
PathwayREACTOME_NOD1_2_SIGNALING_PATHWAY

BIRC2 BIRC3

8.42e-0436172M1059
PathwayPID_FAS_PATHWAY

BIRC2 BIRC3

9.38e-0438172M94
PathwayWP_TNFRELATED_WEAK_INDUCER_OF_APOPTOSIS_TWEAK_SIGNALING

BIRC2 BIRC3

1.15e-0342172M39452
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

POR CYP21A2

1.20e-0343172MM15873
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

NDST3 CYP27C1 CYP21A2

1.28e-03183173M39588
PathwayPID_TNF_PATHWAY

BIRC2 BIRC3

1.37e-0346172M128
PathwayREACTOME_REGULATION_OF_TNFR1_SIGNALING

BIRC2 BIRC3

1.43e-0347172MM15179
PathwayREACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS

BIRC2 BIRC3

1.43e-0347172MM14664
PathwayPID_CASPASE_PATHWAY

BIRC2 BIRC3

1.69e-0351172M220
PathwayREACTOME_TNF_SIGNALING

BIRC2 BIRC3

2.03e-0356172MM15453
PathwayREACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS

BIRC2 BIRC3

2.03e-0356172M1074
PathwayBIOCARTA_HIVNEF_PATHWAY

BIRC2 BIRC3

2.03e-0356172M13968
PathwayREACTOME_TNF_SIGNALING

BIRC2 BIRC3

2.10e-0357172M27713
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

NQO2 POR CYP21A2

2.17e-03220173M10320
PathwayREACTOME_REGULATED_NECROSIS

BIRC2 BIRC3

2.25e-0359172M41803
PathwayREACTOME_REGULATED_NECROSIS

BIRC2 BIRC3

2.25e-0359172MM15169
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC5AC MUC5B

2.33e-0360172MM15636
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC5AC MUC5B

2.48e-0362172M546
PathwayKEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY

BIRC2 BIRC3

2.48e-0362172M15569
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

POR CYP27C1

2.48e-0362172M39653
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

POR CYP21A2

2.64e-0364172M5650
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC5AC MUC5B

2.98e-0368172M27303
PathwayPID_P75_NTR_PATHWAY

BIRC2 BIRC3

2.98e-0368172M153
PathwayWP_GLUCOCORTICOID_RECEPTOR_PATHWAY

BIRC2 BIRC3

3.15e-0370172M40042
PathwayWP_IL18_SIGNALING

BIRC3 ABHD16A EEF2

3.99e-03273173M39818
PathwayWP_APOPTOSIS

BIRC2 BIRC3

4.40e-0383172MM15972
PathwayKEGG_SMALL_CELL_LUNG_CANCER

BIRC2 BIRC3

4.50e-0384172M3228
PathwayKEGG_APOPTOSIS

BIRC2 BIRC3

4.82e-0387172M8492
PathwayWP_APOPTOSIS

BIRC2 BIRC3

4.93e-0388172M39654
PathwayWP_TNFALPHA_SIGNALING

BIRC2 BIRC3

5.38e-0392172M39662
PathwayWP_APOPTOSIS_MODULATION_AND_SIGNALING

BIRC2 BIRC3

5.38e-0392172M39664
PathwayWP_SMALL_CELL_LUNG_CANCER

BIRC2 BIRC3

5.84e-0396172M39834
PathwayREACTOME_TNFR2_NON_CANONICAL_NF_KB_PATHWAY

BIRC2 BIRC3

5.96e-0397172MM15268
PathwayREACTOME_TNFR2_NON_CANONICAL_NF_KB_PATHWAY

BIRC2 BIRC3

6.44e-03101172M27552
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

NQO2 CYP21A2

6.95e-03105172MM14842
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC5AC MUC5B

7.47e-03109172MM15164
PathwayREACTOME_MYD88_INDEPENDENT_TLR4_CASCADE

BIRC2 BIRC3

7.47e-03109172M29565
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC5AC MUC5B

7.74e-03111172M27416
PathwayWP_GASTRIN_SIGNALING

BIRC2 BIRC3

8.28e-03115172M39866
PathwayREACTOME_INNATE_IMMUNE_SYSTEM

BIRC2 MUC5AC BIRC3 MUC5B EEF2

8.91e-031128175M1036
PathwayREACTOME_TOLL_LIKE_RECEPTOR_4_TLR4_CASCADE

BIRC2 BIRC3

9.28e-03122172MM14640
PathwayKEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS

BIRC2 BIRC3

1.13e-02135172M15247
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC5AC MUC5B

1.21e-02140172M27484
PathwayREACTOME_DEATH_RECEPTOR_SIGNALING

BIRC2 BIRC3

1.24e-02142172MM15431
PathwayREACTOME_PROGRAMMED_CELL_DEATH

BIRC2 BIRC3

1.24e-02142172MM15178
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC5AC MUC5B

1.26e-02143172M27275
PathwayWP_METAPATHWAY_BIOTRANSFORMATION

NDST3 CYP21A2

1.43e-02153172MM15844
PathwayREACTOME_DEATH_RECEPTOR_SIGNALING

BIRC2 BIRC3

1.45e-02154172M27697
PathwayREACTOME_TOLL_LIKE_RECEPTOR_CASCADES

BIRC2 BIRC3

1.47e-02155172MM14665
PathwayREACTOME_TOLL_LIKE_RECEPTOR_CASCADES

BIRC2 BIRC3

1.75e-02170172M7494
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5AC MUC5B

3.47e-0722127513696
Pubmed

Mucin deficiency causes functional and structural changes of the ocular surface.

MUC5AC MUC5B

3.47e-07221223272068
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5AC MUC5B

3.47e-07221231030254
Pubmed

c-IAP1 and c-IAP2 redundancy differs between T and B cells.

BIRC2 BIRC3

3.47e-07221223799077
Pubmed

Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy.

BIRC2 BIRC3

3.47e-07221231126323
Pubmed

Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.

MUC5AC MUC5B

3.47e-07221227729120
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5AC MUC5B

3.47e-07221234058148
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5AC MUC5B

3.47e-07221237146737
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5AC MUC5B

3.47e-07221223527003
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5AC MUC5B

3.47e-07221214988081
Pubmed

Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are increased after labour in foetal membranes and myometrium and are essential for TNF-α-induced expression of pro-labour mediators.

BIRC2 BIRC3

3.47e-07221225046208
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5AC MUC5B

3.47e-07221216540890
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5AC MUC5B

3.47e-07221215563276
Pubmed

De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

MUC5AC MUC5B

3.47e-07221236111525
Pubmed

Baculoviral inhibitors of apoptosis repeat containing (BIRC) proteins fine-tune TNF-induced nuclear factor κB and c-Jun N-terminal kinase signalling in mouse pancreatic beta cells.

BIRC2 BIRC3

3.47e-07221223250032
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5AC MUC5B

3.47e-07221217621824
Pubmed

Muc5b is required for airway defence.

MUC5AC MUC5B

3.47e-07221224317696
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5AC MUC5B

3.47e-07221227845589
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5AC MUC5B

3.47e-07221222391959
Pubmed

C-Mannosylation of MUC5AC and MUC5B Cys subdomains.

MUC5AC MUC5B

3.47e-07221214718370
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5AC MUC5B

3.47e-07221235776514
Pubmed

The common P450 oxidoreductase variant A503V is not a modifier gene for 21-hydroxylase deficiency.

POR CYP21A2

3.47e-07221218397975
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5AC MUC5B

3.47e-07221227435107
Pubmed

A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes.

BIRC2 BIRC3

3.47e-07221212651874
Pubmed

Self-termination of the terminator.

BIRC2 BIRC3

3.47e-07221219008929
Pubmed

Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors.

BIRC2 BIRC3

3.47e-07221222434933
Pubmed

IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer.

BIRC2 BIRC3

3.47e-07221220651737
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5AC MUC5B

3.47e-07221224327612
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5AC MUC5B

3.47e-07221226871672
Pubmed

Mucin production during prenatal and postnatal murine lung development.

MUC5AC MUC5B

3.47e-07221221653907
Pubmed

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli.

BIRC2 BIRC3

3.47e-07221210797013
Pubmed

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

MUC5AC MUC5B

3.47e-07221236427316
Pubmed

Nuclear cIAP1 overexpression is a tumor stage- and grade-independent predictor of poor prognosis in human bladder cancer patients.

BIRC2 BIRC3

3.47e-07221221795072
Pubmed

Subcellular expression of c-IAP1 and c-IAP2 in colorectal cancers: relationships with clinicopathological features and prognosis.

BIRC2 BIRC3

3.47e-07221214708638
Pubmed

BIRC2-BIRC3 amplification: a potentially druggable feature of a subset of head and neck cancers in patients with Fanconi anemia.

BIRC2 BIRC3

3.47e-07221234997070
Pubmed

Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.

MUC5AC MUC5B

3.47e-07221232348677
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5AC MUC5B

3.47e-07221211587997
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5AC MUC5B

3.47e-07221228607090
Pubmed

Prognostic Significance of the BIRC2-BIRC3 Gene Signature in Head and Neck Squamous Cell Carcinoma.

BIRC2 BIRC3

3.47e-07221235985688
Pubmed

Genomic organization and physical map of the human inhibitors of apoptosis: HIAP1 and HIAP2.

BIRC2 BIRC3

3.47e-0722129892732
Pubmed

Functional evaluation of the role of inhibitor of apoptosis proteins in chronic lymphocytic leukemia.

BIRC2 BIRC3

3.47e-07221215183896
Pubmed

Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2.

BIRC2 BIRC3

3.47e-07221229452637
Pubmed

Role of IAPs in prostate cancer progression: immunohistochemical study in normal and pathological (benign hyperplastic, prostatic intraepithelial neoplasia and cancer) human prostate.

BIRC2 BIRC3

3.47e-07221220078866
Pubmed

Cellular inhibitors of apoptosis (cIAP) 1 and 2 are increased in placenta from obese pregnant women.

BIRC2 BIRC3

3.47e-07221225113061
Pubmed

Degradation of cIAPs contributes to hepatocyte lipoapoptosis.

BIRC2 BIRC3

3.47e-07221224008361
Pubmed

Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.

MUC5AC MUC5B

3.47e-07221224332705
Pubmed

Genomic characterization of the mouse inhibitor of apoptosis protein 1 and 2 genes.

BIRC2 BIRC3

3.47e-0722129441758
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5AC MUC5B

3.47e-07221234656442
Pubmed

Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization.

BIRC2 BIRC3

1.04e-06321229518103
Pubmed

The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation.

BIRC2 BIRC3

1.04e-06321225065467
Pubmed

Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment.

BIRC2 BIRC3

1.04e-06321218784070
Pubmed

Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.

MUC5AC MUC5B

1.04e-06321227776277
Pubmed

Expression of inhibitor of apoptosis proteins in small- and non-small-cell lung carcinoma cells.

BIRC2 BIRC3

1.04e-06321212243753
Pubmed

To fight or die - inhibitor of apoptosis proteins at the crossroad of innate immunity and death.

BIRC2 BIRC3

1.04e-06321220888210
Pubmed

Smac mimetics activate the E3 ligase activity of cIAP1 protein by promoting RING domain dimerization.

BIRC2 BIRC3

1.04e-06321221393245
Pubmed

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.

MUC5AC MUC5B

1.04e-06321234158522
Pubmed

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death.

BIRC2 BIRC3

1.04e-06321215353805
Pubmed

Assignment of human inhibitor of apoptosis protein (IAP) genes xiap, hiap-1, and hiap-2 to chromosomes Xq25 and 11q22-q23 by fluorescence in situ hybridization.

BIRC2 BIRC3

1.04e-0632128938457
Pubmed

GDC-0152 induces apoptosis through down-regulation of IAPs in human leukemia cells and inhibition of PI3K/Akt signaling pathway.

BIRC2 BIRC3

1.04e-06321225273171
Pubmed

Loss of cIAP1 attenuates soleus muscle pathology and improves diaphragm function in mdx mice.

BIRC2 BIRC3

1.04e-06321223184147
Pubmed

Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.

MUC5AC MUC5B

1.04e-06321229604272
Pubmed

High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.

MUC5AC MUC5B

1.04e-06321229286856
Pubmed

Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.

BIRC2 BIRC3

1.04e-06321219464198
Pubmed

Increased Expression of BIRC2, BIRC3, and BIRC5 from the IAP Family in Mesenchymal Stem Cells of the Umbilical Cord Wharton's Jelly (WJSC) in Younger Women Giving Birth Naturally.

BIRC2 BIRC3

1.04e-06321232322338
Pubmed

IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.

MUC5AC MUC5B

1.04e-06321219596978
Pubmed

Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity.

BIRC2 BIRC3

1.04e-06321221447281
Pubmed

Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.

MUC5AC MUC5B

1.04e-06321236675209
Pubmed

cIAP1/2 negatively regulate RANKL-induced osteoclastogenesis through the inhibition of NFATc1 expression.

BIRC2 BIRC3

1.04e-06321223126497
Pubmed

PERK-dependent regulation of IAP translation during ER stress.

BIRC2 BIRC3

1.04e-06321219029953
Pubmed

Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.

MUC5AC MUC5B

1.04e-06321219556605
Pubmed

Future Therapeutic Directions for Smac-Mimetics.

BIRC2 BIRC3

1.04e-06321232053868
Pubmed

Aquaporin 5 expression increases mucin production in lung adenocarcinoma.

MUC5AC MUC5B

1.04e-06321221455588
Pubmed

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.

MUC5AC MUC5B

1.04e-06321229802623
Pubmed

Gas1 is induced during and participates in excitotoxic neuronal death.

BIRC2 BIRC3

1.04e-06321211906213
Pubmed

Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.

MUC5AC MUC5B

1.04e-06321220422702
Pubmed

Expression of inhibitor of apoptosis proteins in B-cell non-Hodgkin and Hodgkin lymphomas.

BIRC2 BIRC3

1.04e-06321216983704
Pubmed

Inhibitor of apoptosis proteins as novel targets in inflammatory processes.

BIRC2 BIRC3

1.04e-06321221817100
Pubmed

MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression.

BIRC2 BIRC3

1.04e-06321219276372
Pubmed

Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells.

BIRC2 BIRC3

1.04e-06321214960576
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5AC MUC5B

1.04e-06321219718741
Pubmed

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases.

BIRC2 BIRC3

2.08e-0642129545235
Pubmed

Catalytic-independent inhibition of cIAP1-mediated RIP1 ubiquitination by EGLN3.

BIRC2 BIRC3

2.08e-06421226612615
Pubmed

Critical role for antiapoptotic Bcl-xL and Mcl-1 in human macrophage survival and cellular IAP1/2 (cIAP1/2) in resistance to HIV-Vpr-induced apoptosis.

BIRC2 BIRC3

2.08e-06421222403404
Pubmed

Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation.

BIRC2 BIRC3

2.08e-06421228647349
Pubmed

Clinical Positioning of the IAP Antagonist Tolinapant (ASTX660) in Colorectal Cancer.

BIRC2 BIRC3

2.08e-06421234389694
Pubmed

Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated protein.

BIRC2 BIRC3

2.08e-06421210753917
Pubmed

TRIM32 protein sensitizes cells to tumor necrosis factor (TNFα)-induced apoptosis via its RING domain-dependent E3 ligase activity against X-linked inhibitor of apoptosis (XIAP).

BIRC2 BIRC3

2.08e-06421221628460
Pubmed

cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation.

BIRC2 BIRC3

2.08e-06421219223549
Pubmed

cIAP1 Localizes to the nuclear compartment and modulates the cell cycle.

BIRC2 BIRC3

2.08e-06421215665297
Pubmed

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes.

BIRC2 BIRC3

2.08e-0642128552191
Pubmed

A novel role for inhibitor of apoptosis (IAP) proteins as regulators of endothelial barrier function by mediating RhoA activation.

BIRC2 BIRC3

2.08e-06421224371121
Pubmed

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.

MUC5AC MUC5B

2.08e-06421231582416
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5AC MUC5B

2.08e-06421223807779
Pubmed

CIAP2 inhibits anigen receptor signaling by targeting Bcl10 for degredation.

BIRC2 BIRC3

2.08e-06421216775419
Pubmed

A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes.

BIRC2 BIRC3

2.08e-06421232028675
Pubmed

Shigella hijacks the glomulin-cIAPs-inflammasome axis to promote inflammation.

BIRC2 BIRC3

2.08e-06421229191979
Pubmed

IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells.

BIRC2 BIRC3

2.08e-06421217069460
Pubmed

Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome.

BIRC2 BIRC3

2.08e-06421222195745
Pubmed

An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1.

BIRC2 BIRC3

2.08e-06421222332634
Pubmed

Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo.

BIRC2 BIRC3

2.08e-06421215798218
Cytoband11q22

BIRC2 BIRC3

1.09e-051121211q22
Cytoband6p21.3

ABHD16A CYP21A2 BRD2

1.97e-042502136p21.3
CytobandEnsembl 112 genes in cytogenetic band chr11q22

BIRC2 BIRC3

1.10e-03107212chr11q22
Cytoband11p15.5

MUC5AC MUC5B

1.33e-0311821211p15.5
CytobandEnsembl 112 genes in cytogenetic band chr6p21

ABHD16A CYP21A2 BRD2

1.50e-03503213chr6p21
CytobandEnsembl 112 genes in cytogenetic band chr11p15

MUC5AC MUC5B

2.71e-02564212chr11p15
GeneFamilyRing finger proteins|Baculoviral IAP repeat containing|Caspase recruitment domain containing

BIRC2 BIRC3

1.33e-058132419
GeneFamilyCD molecules|Mucins

MUC5AC MUC5B

9.95e-0521132648
GeneFamilyWD repeat domain containing|Caspase recruitment domain containing|Apoptosome

BIRC2 BIRC3

2.05e-0430132959
GeneFamilyRing finger proteins

BIRC2 BIRC3 TRIM48

8.89e-0427513358
CoexpressionGALI_TP53_TARGETS_APOPTOTIC_UP

BIRC2 BIRC3

1.71e-058212M16490
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_mem-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BIRC3 EEF2 CHD7 DNAJC10

1.82e-0619221480a71ab3434076803466ccac0df73468889c7dd3
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_mem|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BIRC3 EEF2 CHD7 DNAJC10

1.82e-0619221475ce635d669ff77d1fd54e10467f21d5e5d67b08
ToppCellCOVID-19_Severe-B_cell|COVID-19_Severe / disease group, cell group and cell class

BIRC3 CHD7 GALR1

4.90e-05153213701a7d92ee7b22277c8462742a530347cc6f061a
ToppCellnormal_Pleural_Fluid-B_lymphocytes-Undetermined|normal_Pleural_Fluid / Location, Cell class and cell subclass

BIRC3 EEF2 CHD7

5.60e-051602135744cd30709f38e84f7ec8893dc19d7a288b465a
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC ABHD16A MUC5B

6.03e-05164213911081739174ec68bc0893c804e4276b206bea7d
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC ABHD16A MUC5B

6.03e-05164213c5bfae7e9497185548c243d6f9ebadbcef48ba7f
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC ABHD16A MUC5B

6.03e-0516421376b0ac220b7ca22fbea28a507f01f96ae9f53932
ToppCellPND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POR MUC5AC MUC5B

6.14e-05165213baff639a7046fb5cacb70f341b6d24cef3519f8e
ToppCellPND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POR MUC5AC MUC5B

6.14e-05165213dd4d36ff8efb89fee1fb4c48d1b8f46902119909
ToppCellPND14-Epithelial-Epithelial_Airway-Neurosecretory|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POR MUC5AC MUC5B

6.14e-051652136fdce8b23736409a23884ef3918638ffc067a86f
ToppCellClub-club-2|World / Class top

POR MUC5B BRD2

6.25e-0516621356f11efb6b686b3ee2c34a051f626e3d761b5112
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B DNAJC10

6.47e-05168213b275e951ff7109e36da22fc17bd4516f9b9432c4
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B DNAJC10

6.47e-05168213a0dbe2ee697e29b32aa5f8326445e067ff66c154
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B DNAJC10

6.47e-051682130757a5af953901a8faed5774ffec4755fc9c0a6e
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B CYP21A2

6.59e-051692131a684471dbda42e1470e5a889648666e14f25982
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B CYP21A2

6.59e-05169213db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B CYP21A2

6.59e-0516921397b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B GALR1

7.06e-05173213e4d9a9a781acc531bc81c3fcee24d637e805c8e1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POR MUC5AC MUC5B

7.06e-051732133aa1d28d4814798a772808ed29e1dbbdf92abd03
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC5AC FHOD3 MUC5B

7.06e-05173213464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POR MUC5AC MUC5B

7.06e-05173213e8afef5ae68983eb8d6515b43952636a47e9d3d4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDST3 TINAG BCO1

7.31e-0517521365571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NQO2 TINAG CYP21A2

7.43e-051762131595dbeee336a81e581325d63208ec6262664ee9
ToppCellClub_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MUC5AC MUC5B CYP27C1

7.68e-05178213be64d4be23fb96a4cdd7980c58880fdfe817747f
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NQO2 ABHD16A DNAJC10

7.81e-05179213af03705a783e77f75c44fdfa793cfdccbf9dd91c
ToppCellnormal-na-Lymphocytic_B-B_mem-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

BIRC3 CHD7 DNAJC10

8.21e-05182213ee36ea6cb9a5a08aeb83f2b7a249255f0b1a9870
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC5AC FHOD3 MUC5B

8.21e-051822133f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POR MUC5AC MUC5B

8.34e-05183213514b72a1ae55656934839800513385e19bc240e2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NQO2 TINAG CYP21A2

8.34e-0518321385446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POR MUC5AC MUC5B

8.48e-0518421349eccf72725593a8fb4a529e7985a5c413b3ca6a
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POR MUC5AC MUC5B

8.48e-0518421341164109d9d7bb1c431220e2e85e08dc5f56856d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B DNAJC10

8.48e-0518421301c19a830348ab0b9c02c1546a439de70ee10f97
ToppCellControl-Epithelial_cells-Tuft-like|Control / group, cell type (main and fine annotations)

MUC5AC MUC5B EEF2

8.75e-051862139aaab2e81b7ed6a75ded2c3fb1170590c57b74ba
ToppCellCOVID-19_Severe-B_memory|World / disease group, cell group and cell class

BIRC3 CHD7 DNAJC10

8.89e-05187213f29c71f2505bb64f3010ada491d422b87a6f7db3
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POR MUC5AC CHD7

8.89e-05187213f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B DNAJC10

9.03e-051882135901b276f2379abf486b8285957277e95f08464e
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

N4BP2L2 EEF2 BRD2

9.03e-05188213d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

MUC5AC FHOD3 MUC5B

9.18e-0518921384d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B DNAJC10

9.32e-051902133c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B DNAJC10

9.32e-0519021323f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BIRC3 EEF2 DNAJC10

9.47e-051912138dda37ebf74b587129795f61541cc511ec97a314
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC ABHD16A MUC5B

9.47e-05191213529068029fb461df766135576dd0d8b5980f9bc0
ToppCellT_cells-Central_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

BIRC3 EEF2 CHD7

9.47e-0519121325dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCellhealthy_donor-Lymphocytic-B_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

BIRC3 CHD7 DNAJC10

9.62e-051922137d9e5772b6e531b50ed4e4d6304ef11235f27f37
ToppCellhealthy_donor-Lymphocytic-B_cell-|healthy_donor / Disease condition, Lineage, Cell class and subclass

BIRC3 CHD7 DNAJC10

9.62e-05192213975312f9d6cede4d4f5b737e481e5c73accc8c50
ToppCellClub_cells|World / lung cells shred on cell class, cell subclass, sample id

MUC5AC MUC5B CYP27C1

9.76e-051932139d3165dc5763a07a7d873f497624d9d6528fa2db
ToppCellCOVID_non-vent-Lymphocytic-B_cell-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

BIRC3 EEF2 CHD7

9.76e-0519321391955c3773c9729a96e82f240f06b072367970d9
ToppCellCOVID_non-vent-Lymphocytic-B_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

BIRC3 EEF2 CHD7

9.76e-0519321332d139f922cd19adc1cc1e0e9a828115be9945d6
ToppCellGoblet|World / shred by cell class for turbinate

POR MUC5AC DNAJC10

9.91e-0519421303b62e7cff5e7a6e7bd7d9dda273c74bf9c1f42e
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BIRC3 CHD7 DNAJC10

9.91e-0519421340c7f9bd69a8e843b81972e25a67f591021415dd
ToppCellSevere-CD4+_T|World / Disease group and Cell class

BIRC3 EEF2 CHD7

9.91e-051942132ad888f78765ecfb8d1ea978c75c90fa3030509a
ToppCellCV-Severe-6|Severe / Virus stimulation, Condition and Cluster

POR BIRC2 BIRC3

9.91e-05194213d33be6ed1de907aeea0c2dce09796556b8efdd4e
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BIRC3 CHD7 DNAJC10

1.01e-0419521351e6cfecd66a874673d0b79a295489a358bddfd5
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BIRC3 N4BP2L2 EEF2

1.01e-041952135001e68df2ad5df9dc93ae235f984ffafea6b521
ToppCellEpithelial_cells-Club_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

MUC5AC MUC5B CYP27C1

1.01e-04195213b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BIRC3 N4BP2L2 EEF2

1.01e-0419521307035a5972a78b98e4ab2167e3a5000f9f3b0826
ToppCellSevere-CD4+_T|Severe / Disease group and Cell class

BIRC3 EEF2 CHD7

1.02e-04196213576e0aa2ae146a86201dea21097ffe1c867956e7
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B DNAJC10

1.02e-041962132c3fbfbb08cd327cd97b3fa5a6f83b6d50771fb7
ToppCell(05)_Secretory|World / shred by cell type by condition

MUC5AC BIRC3 MUC5B

1.02e-041962138032c25b51ef96aeba28cc52686a2bd45213453d
ToppCelldistal-Epithelial-Goblet|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC5AC MUC5B BCO1

1.04e-04197213da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC5AC MUC5B BCO1

1.04e-04197213a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BIRC3 N4BP2L2 EEF2

1.04e-041972139373fcd728016b7af1abd7d88c47b7db79eb6a2f
ToppCellCOVID-19_Severe-CD4+_T_naive|COVID-19_Severe / Disease condition and Cell class

BIRC3 EEF2 CHD7

1.04e-04197213ac26672bd2cb3bc9a11206d8da203bafec3931f6
ToppCelldistal-Epithelial-Goblet-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC5AC MUC5B BCO1

1.04e-041972133fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BIRC3 N4BP2L2 EEF2

1.05e-041982134c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BIRC3 N4BP2L2 EEF2

1.05e-04198213239bef79ebaa6e1d8618c670c1050a02362058ee
ToppCellControl-Epithelial_cells-Cycling_epithelial|Control / group, cell type (main and fine annotations)

MUC5AC MUC5B EEF2

1.05e-04198213b43290d2f8ca45b4a21cb6dbdf1b4384897672e0
ToppCelldistal-Epithelial-Mucous-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC5AC MUC5B CYP21A2

1.07e-0419921335fb7bd35e53d8ca189fe8c7744211a5201081f6
ToppCellT_cells-CCR7+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

BIRC3 EEF2 CHD7

1.07e-04199213467820d6abe3024d9d655b9672c2f9cdc1303db3
ToppCellmild-B_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BIRC3 CHD7 DNAJC10

1.08e-04200213222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BIRC3 EEF2 BRD2

1.08e-0420021355f19f990fa02664aa02812f6fc65f93d5e7f382
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CHD7 DNAJC10

4.92e-047021237e34ef782b253c43628d5bb2fe5e0294573d0ef
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-6|TCGA-Cervix / Sample_Type by Project: Shred V9

BIRC2 BIRC3

1.23e-0311121245a8e069369fdc7358135bf2229defbee1ac2600
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-double-positive,_alpha-beta_thymocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC5AC MUC5B

1.46e-0312121225fa58d8e07dab572b2ba8e23c9d1ad3502dfc56
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Non-Seminoma-_Embryonal_Carcinoma|TCGA-Testes / Sample_Type by Project: Shred V9

G6PC3 TRIM48

1.91e-031392126b58d01ce9d9ac23434333f9faf1bb0eef14ba90
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NDST3 GALR1

2.05e-0314421208005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellTCGA-Adrenal|World / Sample_Type by Project: Shred V9

CYP21A2 GALR1

2.08e-03145212522ad2bc90b8ec326fcbc7b2250b09566efeeca2
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BIRC2 CYP27C1

2.11e-03146212cffa91d76606f74553d81150adbb23b003746316
ToppCellClub_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

MUC5AC MUC5B

2.14e-031472125a824c89e4d045af465d7333275f8191fb29b041
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MUC5B TINAG

2.14e-03147212aba44c7057096483c4293a7ebcf8ccc8baed0231
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

G6PC3 BRD2

2.14e-03147212f703cb0330304799d16e457215269c7732c9d5d5
ToppCellCOVID-19_Severe-B_cell|World / disease group, cell group and cell class

CHD7 GALR1

2.20e-031492129a9fcbf7e8a6811958f3fd2d36315e19ab2b1127
ToppCellClub_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MUC5AC MUC5B

2.20e-0314921281c813588bb5efb7b31141a75d387210dcb76094
ToppCellfacs-Aorta-Heart-3m-Epithelial|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDST3 MUC5B

2.25e-03151212bee48137d1f5f27a24571a59c835284651d38538
ToppCellfacs-Aorta-Heart-3m-Epithelial-epithelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDST3 MUC5B

2.25e-031512120de76acd1b204345dce7f33be2a1ed9fbe9e6da0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EEF2 GALR1

2.25e-031512123744e4ed87703a97002e001afd16490d525a5128
ToppCellfacs-Aorta-Heart-3m-Epithelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDST3 MUC5B

2.25e-0315121220b9c8fb966c5d62ff909cc4a4616b109b78cdca
ToppCellP15-Epithelial-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MUC5B TINAG

2.28e-0315221200d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FHOD3 MUC5B

2.28e-031522121b2a39ae159e79f1fb18d6d164bd7acab5299fca
ToppCellfrontal_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

NQO2 NDST3

2.28e-03152212f9c29d4568402ca07a717dbffb3ccc7f35c5fe56
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B CYP21A2

2.31e-03153212edf5d026e8e4c685b7c369d70894741bb2cd568e
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B CYP21A2

2.31e-031532123240d4d690335ba22317b1f3d33f9ea069e93838
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B CYP21A2

2.34e-03154212ec56b7fb88e39041416c384f371c767f3b4e92fa
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

2.37e-0315521262b59cb32b12bd55b19e98786a866d788fc9e4bf
ToppCellGoblet|World / Class top

MUC5B DNAJC10

2.43e-03157212b352aa37d662629db6a9c6def9ee6d7c49a9071c
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

2.43e-03157212c43f2e1ea53b375a7432f17f87cfef3b2261003d
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

BIRC3 GALR1

2.43e-031572127ceae5fe00c91d4feb8c314d3a31f027c03fa56f
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDST3 FHOD3

2.46e-03158212f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDST3 FHOD3

2.46e-031582128c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FHOD3 CYP27C1

2.46e-03158212d78e7e52657dc094430291fec07e9c298be9e584
ComputationalAnti-apoptosis.

BIRC2 BIRC3

2.44e-0417152MODULE_537
DrugT0M

POR BIRC2 BIRC3

1.48e-0712213CID000017116
Drugembelin

G6PC3 BIRC2 BIRC3

2.18e-0628213CID000003218
DrugAkt-I-1 compound

BIRC2 BIRC3

2.43e-063212ctd:C501520
Drugaclacinomycins

BIRC2 BIRC3

2.43e-063212ctd:C011157
DrugCapsaicin

NQO2 POR BIRC2 MUC5AC MUC5B EEF2

3.88e-06488216ctd:D002211
Druggamma-secretase inhibitor I

BIRC2 BIRC3

4.86e-064212CID011754711
DrugAVPW

BIRC2 BIRC3

8.09e-065212CID009549245
DrugNSC-725021

BIRC2 BIRC3

1.21e-056212CID000406741
Drugtephrosin

BIRC2 BIRC3

1.21e-056212ctd:C480848
Drugkamebakaurin

BIRC2 BIRC3

1.21e-056212ctd:C047382
DrugDendroaspis natriuretic peptide

BIRC2 BIRC3

1.21e-056212ctd:C075597
DrugSN 23862

NQO2 POR

1.70e-057212CID000126690
DrugAklavin hydrochloride

BIRC2 BIRC3

1.70e-057212CID000002074
Drugpotassium ferricyanide

G6PC3 NQO2 POR

1.82e-0556213CID000026250
Druggastrin 17

BIRC2 BIRC3

2.26e-058212ctd:C013550
Drugdelta 5-pregnenediol

POR CYP21A2

2.26e-058212CID000094194
Drugthiobenzamide S-oxide

G6PC3 POR

2.26e-058212CID000099495
Drug1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate

BIRC2 BIRC3

2.26e-058212ctd:C477931
Drugisoalloxazine

NQO2 POR BRD2

3.41e-0569213CID005372720
Drugdiethylstilbestrol quinone

NQO2 POR

3.63e-0510212CID003034826
Drugtetronic acid

BIRC2 BIRC3

3.63e-0510212CID000521261
DrugGold

POR BIRC2 BIRC3 EEF2 DNAJC10

3.80e-05432215ctd:D006046
Druganthraquinone-2-sulfonate

NQO2 POR

4.43e-0511212CID000008551
Drugajoene

BIRC2 BIRC3

4.43e-0511212ctd:C048980
DrugSM 164

BIRC2 BIRC3

4.43e-0511212ctd:C533467
Drug5-phenylselenylmethyl-2'-deoxyuridine

BIRC2 BIRC3

4.43e-0511212ctd:C558289
Drug5-methylselenylmethyl-2'-deoxyuridine

BIRC2 BIRC3

4.43e-0511212ctd:C558288
Drug3-methylcholanthrene

G6PC3 NQO2 POR CYP21A2

5.40e-05231214CID000001674
DrugS)-HDAC42

BIRC2 BIRC3

6.28e-0513212CID006918801
Drugcyprodime hydrobromide

MUC5AC BRD2

6.28e-0513212CID005748293
Drug5-hydroxy-2(5H)-furanone

BIRC2 BIRC3

6.28e-0513212CID000021076
DrugBendamustine Hydrochloride

BIRC2 BIRC3

6.28e-0513212ctd:D000069461
Drugent-1,3,6,11-tetrahydroxykaur-16-ene-15-one 3,11-diacetate

BIRC2 BIRC3

7.32e-0514212ctd:C530049
Drugdehydroxymethylepoxyquinomicin

BIRC2 BIRC3

8.45e-0515212ctd:C464444
Druglapachol

NQO2 POR

9.65e-0516212CID000003884
Drug4-methylene-2-octyl-5-oxofuran-3-carboxylic acid

BIRC2 BIRC3

1.09e-0417212ctd:C406734
DrugFlavin-Adenine Dinucleotide

NQO2 POR

1.23e-0418212DB03147
Drugdeca-2,4-dienal

BIRC2 BIRC3

1.37e-0419212CID000016899
DrugAC1L235Y

BIRC2 BIRC3

1.37e-0419212CID000065390
Drugmenadione

NQO2 POR BIRC2 BIRC3

1.48e-04300214CID000004055
Drug3-(4-methylphenylsulfonyl)-2-propenenitrile

BIRC2 MUC5AC BIRC3

1.48e-04113213ctd:C434003
DrugBP-3,6-quinone

NQO2 POR

1.52e-0420212CID000018301
DrugAC1Q7AUJ

G6PC3 POR CYP21A2

1.64e-04117213CID000003303
DrugBP-1,6-quinone

NQO2 POR

1.85e-0422212CID000018300
Drug17 alpha-hydroxy-20 beta-dihydroprogesterone

POR CYP21A2

1.85e-0422212CID000107701
Drughydroxyphenylglycine

EEF2 BRD2

1.85e-0422212CID000067149
Druglonafarnib

BIRC2 BIRC3 EEF2

1.95e-04124213CID000148195
Drughyperforin

POR EEF2

2.03e-0423212ctd:C001654
Drughexobarbital

G6PC3 POR CYP21A2

2.09e-04127213CID000003608
DrugAC1L2LVM

BIRC2 BIRC3

2.21e-0424212CID000023204
Drugepicholesterol

G6PC3 POR ABHD16A CYP27C1 CYP21A2

2.35e-04636215CID000000304
Drugdanthron

BIRC2 BIRC3

2.40e-0425212ctd:C004315
Drugthiobenzamide

G6PC3 POR

2.60e-0426212CID000683563
Druglonafarnib

BIRC2 BIRC3

2.60e-0426212ctd:C115354
DrugNSC400385

BIRC2 BIRC3

2.60e-0426212CID000259185
Drugdiphthamide

EEF2 BRD2

2.80e-0427212CID005460185
Drugtetra-chloride

G6PC3 POR

3.02e-0428212CID000076700
Drugnivalenol

MUC5AC MUC5B

3.02e-0428212ctd:C038405
DrugCB1954

NQO2 POR

3.24e-0429212CID000089105
Drugquebrachitol

BIRC2 BIRC3

3.24e-0429212CID000151108
Drug1'-acetoxychavicol acetate

BIRC2 BIRC3

3.71e-0431212ctd:C047948
Drugthioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA

MUC5AC BIRC3 MUC5B

3.83e-041562131010_UP
DrugCHAPS detergent

NQO2 POR BCO1

3.98e-04158213CID000107670
Drug4-Aminopyridine

BIRC2 BIRC3

4.20e-0433212ctd:D015761
Drugevodiamine

BIRC2 BIRC3

4.47e-0434212ctd:C049639
Drugdibenzothiophene

NQO2 BCO1

4.73e-0435212CID000003023
Drugriboflavin 5'-phosphate

NQO2 POR BRD2

5.01e-04171213CID000000710
Drugaminopyrine

G6PC3 POR CYP21A2

5.01e-04171213CID000006009
DrugCompound 10

BIRC2 BIRC3

5.29e-0437212CID003749170
DrugRo 41-5253

MUC5AC BCO1

5.29e-0437212CID005312120
Drugbendamustine

BIRC2 BIRC3

5.29e-0437212CID000065628
DrugAC1L32JY

NQO2 POR

5.29e-0437212CID000107685
DrugK-K-K

NQO2 POR CYP21A2

5.36e-04175213CID000003823
DrugAC1NR9P8

BIRC2 BIRC3

5.58e-0438212CID005287445
Drugtaurolidine

BIRC2 BIRC3

5.88e-0439212CID000029566
Drugo-phenylphenol

NQO2 POR

5.88e-0439212CID000007017
Drugquinol

NQO2 POR BIRC3

5.91e-04181213CID000000785
Drug1,2-naphthoquinone

NQO2 POR

6.19e-0440212CID000010667
DrugAC1L1GSB

BIRC2 BIRC3

6.19e-0440212CID000003819
DrugHomochlorcyclizine dihydrochloride [1982-36-1]; Up 200; 10.4uM; PC3; HT_HG-U133A

MUC5AC BIRC3 CHD7

6.20e-041842137295_UP
DrugForskolin, from Coleus forskohlii; Up 200; 0.5uM; MCF7; HT_HG-U133A

POR MUC5AC MUC5B

6.30e-041852137055_UP
Drugsulforaphane

NQO2 BIRC2 BIRC3

6.71e-04189213CID000005350
DrugPTBP

BIRC2 BIRC3

6.82e-0442212CID000007393
DrugN,N-dimethylaniline

G6PC3 POR

6.82e-0442212CID000000949
Drug0173570-0000 [211245-44-2]; Up 200; 10uM; MCF7; HT_HG-U133A

BIRC3 MUC5B BCO1

7.13e-041932134712_UP
DrugClotrimazole [23593-75-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A

MUC5AC CHD7 BCO1

7.13e-041932133166_UP
DrugZuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; HL60; HT_HG-U133A

G6PC3 POR BIRC3

7.45e-041962132936_DN
DrugMetronidazole [443-48-1]; Down 200; 23.4uM; PC3; HG-U133A

G6PC3 N4BP2L2 DNAJC10

7.45e-041962131921_DN
DrugFenbufen [36330-85-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A

MUC5AC MUC5B BCO1

7.56e-041972132308_UP
DrugImipenem [74431-23-5]; Up 200; 13.4uM; PC3; HT_HG-U133A

MUC5AC BIRC3 N4BP2L2

7.68e-041982137294_UP
DrugEthambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; HL60; HG-U133A

POR EEF2 DNAJC10

7.68e-041982131981_UP
DrugTN-2

BIRC2 BIRC3

7.83e-0445212CID006852143
DrugAC1L1BJZ

POR GALR1

7.83e-0445212CID000026634
Drug17-hydroxypregnenolone

POR CYP21A2

8.18e-0446212CID000091451
Drugchrysoin

BIRC2 BIRC3

8.18e-0446212CID005464545
Drugethanol

G6PC3 POR MUC5AC EEF2 CYP21A2

8.26e-04837215CID000000702
DrugDEET

POR CYP27C1 CYP21A2

8.37e-04204213ctd:D003671
DrugAC1L1KZZ

BIRC2 BIRC3

8.54e-0447212CID000005725
Drugzerumbone

BIRC2 BIRC3

8.91e-0448212ctd:C403304
DrugAC1NRAJO

BIRC2 BIRC3

8.91e-0448212CID005287929
Diseasecongenital adrenal hyperplasia (is_implicated_in)

POR CYP21A2

7.22e-066212DOID:0050811 (is_implicated_in)
DiseaseCongenital adrenal hyperplasia

POR CYP21A2

1.73e-059212C0001627
Diseasepulmonary fibrosis

MUC5AC MUC5B

2.64e-0511212EFO_0009448
Diseaseaspartate measurement

NDST3 CYP21A2

1.32e-0424212EFO_0010462
Diseasecolorectal cancer (is_marker_for)

BIRC2 BIRC3 EEF2

1.83e-04157213DOID:9256 (is_marker_for)
Diseaselung non-small cell carcinoma (is_marker_for)

BIRC2 BIRC3 EEF2

2.28e-04169213DOID:3908 (is_marker_for)
Diseaseurinary albumin to creatinine ratio

POR CHD7 CYP21A2

2.69e-04179213EFO_0007778
DiseaseCOVID-19 symptoms measurement

MUC5AC MUC5B

2.83e-0435212EFO_0600019
Diseasemetabolite measurement

NQO2 POR CYP21A2 BCO1

5.94e-04560214EFO_0004725
Diseaseurinary metabolite measurement

NQO2 CYP21A2 TRIM48

6.73e-04245213EFO_0005116
Diseaseleukemia

BIRC2 BIRC3

7.00e-0455212C0023418
Diseaseidiopathic pulmonary fibrosis

MUC5AC MUC5B

7.52e-0457212EFO_0000768
Diseasepancreatic ductal carcinoma (is_marker_for)

MUC5AC MUC5B

8.61e-0461212DOID:3587 (is_marker_for)
Diseasecystic fibrosis (is_marker_for)

MUC5AC MUC5B

8.89e-0462212DOID:1485 (is_marker_for)
Diseaseoral squamous cell carcinoma (is_marker_for)

BIRC2 BIRC3

9.18e-0463212DOID:0050866 (is_marker_for)
Diseasecholangiocarcinoma (is_marker_for)

MUC5AC MUC5B

9.47e-0464212DOID:4947 (is_marker_for)
Diseaseinterstitial lung disease

MUC5AC MUC5B

1.04e-0367212EFO_0004244
Diseasecitrate measurement

POR CYP21A2

1.44e-0379212EFO_0010114
Diseaseeosinophil percentage of leukocytes

POR MUC5AC CHD7 CYP21A2

1.72e-03746214EFO_0007991
Diseasehypertrophic cardiomyopathy

FHOD3 TRIM48

1.94e-0392212EFO_0000538
Diseasealbuminuria

CHD7 CYP21A2

2.03e-0394212EFO_0004285

Protein segments in the cluster

PeptideGeneStartEntry
FIPKPWREFCRSWDG

CYP27C1

281

Q4G0S4
FDFRSWPVDFHWEEP

ABHD16A

151

O95870
DDPWVQHAKWFPRCE

BIRC3

306

Q13489
PFHAEVPADWWDKEA

CHD7

1776

Q9P2D1
PKCEWTEWFDVDFPT

MUC5B

1786

Q9HC84
DCLLGSVDEFWWFPH

NDST3

366

O95803
FITWREQFWPAVCEH

POR

216

P16435
AFKWCERPEWIHVDS

G6PC3

231

Q9BUM1
TVWERPHEFWPDRFL

CYP21A2

396

P08686
HPRCTWTKWFDVDFP

MUC5AC

3521

P98088
DCHPLCAWTKWFDVD

MUC5AC

4626

P98088
WKEEPIPCTAHWHFG

NQO2

216

P16083
FCWEQWPDPRHKKAY

GALR1

186

P47211
LFWNEVRPFDWPCKN

FHOD3

896

Q2V2M9
WDVAEARKIWCFGPD

EEF2

641

P13639
NDKEPWLVDFFAPWC

DNAJC10

466

Q8IXB1
RHCPAEWAAEEHWEK

TRIM48

141

Q8IWZ4
DPWVEHAKWFPRCEF

BIRC2

321

Q13490
WKHQFAWPFRQPVDA

BRD2

91

P25440
LKWREDDCWPAEPLF

BCO1

446

Q9HAY6
FCREEKEWPPHTQPW

TINAG

101

Q9UJW2
FHEPETWWKFDPEEL

N4BP2L2

501

Q92802