Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalkaline phosphatase activity

ALPL ALPG

2.18e-046772GO:0004035
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

TAOK2 CKB JAK1 ERVK-6 PHKG2 ERBB3 NEK10 FAM20B ERVK-7 CLP1 NME7 MYLK2

2.36e-049387712GO:0016772
GeneOntologyBiologicalProcessfutile creatine cycle

CKB ALPL

1.30e-052752GO:0140651
GeneOntologyCellularComponentWnt-Frizzled-LRP5/6 complex

LRP6 LRP5

1.33e-045772GO:1990851
DomainTMEM183

TMEM183A TMEM183BP

1.51e-052732IPR026509
DomainLRP5/6

LRP6 LRP5

1.51e-052732IPR017049
DomainAlk_phosphatase

ALPL ALPG

9.00e-054732PF00245
DomainAlkaline_phosphatase_AS

ALPL ALPG

9.00e-054732IPR018299
DomainAlkaline_phosphatase

ALPL ALPG

9.00e-054732IPR001952
DomainalkPPc

ALPL ALPG

9.00e-054732SM00098
DomainALKALINE_PHOSPHATASE

ALPL ALPG

9.00e-054732PS00123
Pubmed

Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6.

CKB A2M LRP6

5.80e-07877316384981
Pubmed

Morphological characteristics of SETD2-mutated locally advanced clear cell renal cell carcinoma: Comparison with BAP1-mutated clear cell renal cell carcinoma.

SETD2 BAP1

4.84e-06277237976977
Pubmed

Evidence against a human cell-specific role for LRP6 in anthrax toxin entry.

LRP6 LRP5

4.84e-06277218350154
Pubmed

Clinical Phenotype and Relevance of LRP5 and LRP6 Variants in Patients With Early-Onset Osteoporosis (EOOP).

LRP6 LRP5

4.84e-06277233118644
Pubmed

Dissecting molecular differences between Wnt coreceptors LRP5 and LRP6.

LRP6 LRP5

4.84e-06277221887268
Pubmed

PAR1&2 driven placenta EVT invasion act via LRP5/6 as coreceptors.

LRP6 LRP5

4.84e-06277233136328
Pubmed

Lack of association of LRP5 and LRP6 polymorphisms with type 2 diabetes mellitus in the Japanese population.

LRP6 LRP5

4.84e-06277218493104
Pubmed

Origination and evolution of a human-specific transmembrane protein gene, c1orf37-dup.

TMEM183A TMEM183BP

4.84e-06277216644869
Pubmed

LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way.

LRP6 LRP5

4.84e-06277215084453
Pubmed

Lrp5 and Lrp6 are required for maintaining self-renewal and differentiation of hematopoietic stem cells.

LRP6 LRP5

4.84e-06277230668923
Pubmed

Characterization of alkaline phosphatase genes expressed in seminoma by cDNA cloning.

ALPL ALPG

4.84e-0627729823315
Pubmed

Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts.

LRP6 LRP5

4.84e-06277222433869
Pubmed

Co-deletion of Lrp5 and Lrp6 in the skeleton severely diminishes bone gain from sclerostin antibody administration.

LRP6 LRP5

4.84e-06277233164872
Pubmed

LRP5/6 directly bind to Frizzled and prevent Frizzled-regulated tumour metastasis.

LRP6 LRP5

4.84e-06277225902418
Pubmed

Wnt-Lrp5 signaling regulates fatty acid metabolism in the osteoblast.

LRP6 LRP5

4.84e-06277225802278
Pubmed

Expression of the sodium-driven chloride bicarbonate exchanger NCBE during prenatal mouse development.

SLC4A10 SLC12A5

4.84e-06277215567717
Pubmed

Adverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators BAP1 and SETD2: a report by MSKCC and the KIRC TCGA research network.

SETD2 BAP1

4.84e-06277223620406
Pubmed

The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta-analysis.

LRP6 LRP5

4.84e-06277230474181
Pubmed

In Adult Skeletal Muscles, the Co-Receptors of Canonical Wnt Signaling, Lrp5 and Lrp6, Determine the Distribution and Size of Fiber Types, and Structure and Function of Neuromuscular Junctions.

LRP6 LRP5

4.84e-06277236552732
Pubmed

Idiopathic Juvenile Osteoporosis: Clinical Experience from a Single Centre and Screening of LRP5 and LRP6 Genes.

LRP6 LRP5

4.84e-06277225783012
Pubmed

Gene targeting approaches in mice: assessing the roles of LRP5 and LRP6 in osteoblasts.

LRP6 LRP5

4.84e-06277219147944
Pubmed

Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.

LRP6 LRP5

4.84e-06277215537447
Pubmed

Distinct roles of LRP5 and LRP6 in Wnt signaling regulation in the retina.

LRP6 LRP5

4.84e-06277233545636
Pubmed

LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin.

LRP6 LRP5

4.84e-06277217335347
Pubmed

Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density.

LRP6 LRP5

4.84e-06277212579474
Pubmed

The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development.

LRP6 LRP5

4.84e-06277219503830
Pubmed

LRP5-/6 gene polymorphisms and its association with risk of abnormal bone mass in postmenopausal women.

LRP6 LRP5

4.84e-06277237202775
Pubmed

Wnt receptors, bone mass, and fractures: gene-wide association analysis of LRP5 and LRP6 polymorphisms with replication.

LRP6 LRP5

4.84e-06277220926594
Pubmed

Common genetic variation of the low-density lipoprotein receptor-related protein 5 and 6 genes determines fracture risk in elderly white men.

LRP6 LRP5

4.84e-06277216355283
Pubmed

Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo.

LRP6 LRP5

4.84e-06277228425175
Pubmed

Canonical Wnt Signaling in CD11c+ APCs Regulates Microbiota-Induced Inflammation and Immune Cell Homeostasis in the Colon.

LRP6 LRP5

1.45e-05377229602775
Pubmed

Genomic alterations as predictors of survival among patients within a combined cohort with clear cell renal cell carcinoma undergoing cytoreductive nephrectomy.

SETD2 BAP1

1.45e-05377228408295
Pubmed

PBRM1, SETD2 and BAP1 - the trinity of 3p in clear cell renal cell carcinoma.

SETD2 BAP1

1.45e-05377236253570
Pubmed

Multivesicular GSK3 sequestration upon Wnt signaling is controlled by p120-catenin/cadherin interaction with LRP5/6.

LRP6 LRP5

1.45e-05377224412065
Pubmed

LRP5 in premature adrenarche and in metabolic characteristics of prepubertal children.

LRP6 LRP5

1.45e-05377218721193
Pubmed

tPA regulates neurite outgrowth by phosphorylation of LRP5/6 in neural progenitor cells.

LRP6 LRP5

1.45e-05377223925701
Pubmed

Structural insight into the mechanisms of Wnt signaling antagonism by Dkk.

LRP6 LRP5

1.45e-05377218524778
Pubmed

Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation.

LRP6 LRP5

1.45e-05377225710911
Pubmed

The structural basis of DKK-mediated inhibition of Wnt/LRP signaling.

LRP6 LRP5

1.45e-05377222589387
Pubmed

Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma.

SETD2 BAP1

1.45e-05377230660076
Pubmed

Wnt co-receptor LRP5/6 overexpression confers protection against hydrogen peroxide-induced neurotoxicity and reduces tau phosphorylation in SH-SY5Y cells.

LRP6 LRP5

1.45e-05377225959626
Pubmed

Opposing Roles of Wnt Inhibitors IGFBP-4 and Dkk1 in Cardiac Ischemia by Differential Targeting of LRP5/6 and β-catenin.

LRP6 LRP5

1.45e-05377227803037
Pubmed

Two structural and functional domains of MESD required for proper folding and trafficking of LRP5/6.

LRP6 LRP5

1.45e-05377221397183
Pubmed

Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6.

LRP6 LRP5

1.45e-05377222000856
Pubmed

The effect of adrenocorticotropic hormone on alpha-2-macroglobulin in osteoblasts derived from human mesenchymal stem cells.

A2M ALPL

1.45e-05377232163666
Pubmed

Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts.

LRP6 LRP5

1.45e-05377218406176
Pubmed

Molecular simulation analysis of the structure complex of C2 domains of DKK family members and β-propeller domains of LRP5/6: explaining why DKK3 does not bind to LRP5/6.

LRP6 LRP5

1.45e-05377224743782
Pubmed

The long non-coding RNA lncFOXO1 suppresses growth of human breast cancer cells through association with BAP1.

FOXO1 BAP1

1.45e-05377228339037
Pubmed

Loss of endothelial glucocorticoid receptor promotes angiogenesis via upregulation of Wnt/β-catenin pathway.

LRP6 LRP5

1.45e-05377233650028
Pubmed

Lrp5 and Lrp6 play compensatory roles in mouse intestinal development.

LRP6 LRP5

1.45e-05377221866564
Pubmed

Genomic aberrations frequently alter chromatin regulatory genes in chordoma.

SETD2 BAP1

1.45e-05377227072194
Pubmed

Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.

LRP6 LRP5

1.45e-05377230664649
Pubmed

Peptide-based mediated disruption of N-cadherin-LRP5/6 interaction promotes Wnt signaling and bone formation.

LRP6 LRP5

1.45e-05377222576936
Pubmed

Integration of Recurrent Somatic Mutations with Clinical Outcomes: A Pooled Analysis of 1049 Patients with Clear Cell Renal Cell Carcinoma.

SETD2 BAP1

1.45e-05377228753773
Pubmed

Investigating the Role of FoxP3 in Renal Cell Carcinoma Metastasis with BAP1 or SEDT2 Mutation.

SETD2 BAP1

1.45e-05377237569676
Pubmed

Depletion of canonical Wnt signaling components has a neuroprotective effect on midbrain dopaminergic neurons in an MPTP-induced mouse model of Parkinson's disease.

LRP6 LRP5

1.45e-05377225009587
Pubmed

Computational analysis of the mutations in BAP1, PBRM1 and SETD2 genes reveals the impaired molecular processes in renal cell carcinoma.

SETD2 BAP1

1.45e-05377226452128
Pubmed

TRAP1 Regulates Wnt/β-Catenin Pathway through LRP5/6 Receptors Expression Modulation.

LRP6 LRP5

1.45e-05377233065966
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

TAOK2 PHF2 SETD2 MDN1 ACAD11 CLPB APLP2 IPO4 CLP1 ANKHD1 EPB41L1 MYLK2 C2CD2L

2.33e-051497771331527615
Pubmed

Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice.

FRY FAM20B LRP5

2.62e-052677333905568
Pubmed

Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors.

LRP6 LRP5

2.89e-05477222696217
Pubmed

Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function.

LRP6 LRP5

2.89e-05477221471202
Pubmed

NSD1-deposited H3K36me2 directs de novo methylation in the mouse male germline and counteracts Polycomb-associated silencing.

SETD2 ALPL

2.89e-05477232929285
Pubmed

Lrp5/6 are required for cerebellar development and for suppressing TH expression in Purkinje cells via β-catenin.

LRP6 LRP5

2.89e-05477226772978
Pubmed

Structural evidence of functional divergence in human alkaline phosphatases.

ALPL ALPG

2.89e-05477212372831
Pubmed

The Wnt-β-Catenin-IL-10 Signaling Axis in Intestinal APCs Protects Mice from Colitis-Associated Colon Cancer in Response to Gut Microbiota.

LRP6 LRP5

2.89e-05477232917787
Pubmed

Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts.

LRP6 LRP5

2.89e-05477229176883
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7

2.89e-05477210469592
Pubmed

Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity.

LRP6 LRP5

2.89e-05477217002572
Pubmed

Oligomerization of Frizzled and LRP5/6 protein initiates intracellular signaling for the canonical WNT/β-catenin pathway.

LRP6 LRP5

2.89e-05477230361437
Pubmed

Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins.

LRP6 LRP5

2.89e-05477215064719
Pubmed

Differential expression of DKK-1 binding receptors on stromal cells and myeloma cells results in their distinct response to secreted DKK-1 in myeloma.

LRP6 LRP5

2.89e-05477220846389
Pubmed

Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism.

LRP6 LRP5

2.89e-05477218502762
Pubmed

Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow.

LRP6 LRP5

2.89e-05477211433302
Pubmed

Aberrant promoter hypermethylation of PBRM1, BAP1, SETD2, KDM6A and other chromatin-modifying genes is absent or rare in clear cell RCC.

SETD2 BAP1

2.89e-05477223644518
Pubmed

Stage-specific expression patterns of alkaline phosphatase during development of the first arch skeleton in inbred C57BL/6 mouse embryos.

ALPL ALPG

2.89e-0547729061447
Pubmed

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor.

LRP6 LRP5

2.89e-05477215908424
Pubmed

Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition.

LRP6 LRP5

2.89e-05477223675479
Pubmed

Shh Plays an Inhibitory Role in Cusp Patterning by Regulation of Sostdc1.

LRP6 LRP5

2.89e-05477230325689
Pubmed

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice.

LRP6 LRP5

2.89e-05477231452509
Pubmed

Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation.

LRP6 LRP5

2.89e-05477218762581
Pubmed

The role of Lrp5/6 in cardiac valve disease: experimental hypercholesterolemia in the ApoE-/- /Lrp5-/- mice.

LRP6 LRP5

2.89e-05477221678468
Pubmed

Critical Endothelial Regulation by LRP5 during Retinal Vascular Development.

LRP6 LRP5

2.89e-05477227031698
Pubmed

Inactivation of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia.

ALPL ALPG

2.89e-0547729056646
Pubmed

Hepatocyte growth factor (Hgf) stimulates low density lipoprotein receptor-related protein (Lrp) 5/6 phosphorylation and promotes canonical Wnt signaling.

LRP6 LRP5

4.82e-05577224692544
Pubmed

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6.

LRP6 LRP5

4.82e-05577211448771
Pubmed

Radiogenomics of clear cell renal cell carcinoma: associations between CT imaging features and mutations.

SETD2 BAP1

4.82e-05577224029645
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7

4.82e-05577212629516
Pubmed

Analysis of association of LRP5, LRP6, SOST, DKK1, and CTNNB1 genes with bone mineral density in a Slovenian population.

LRP6 LRP5

4.82e-05577219898734
Pubmed

Inhibition of the canonical Wnt signaling pathway by apolipoprotein E4 in PC12 cells.

LRP6 LRP5

4.82e-05577216805831
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7

4.82e-05577211401426
Pubmed

β-catenin signaling in murine liver zonation and regeneration: a Wnt-Wnt situation!

LRP6 LRP5

4.82e-05577224700412
Pubmed

TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer.

LRP6 LRP5

4.82e-05577231262711
Pubmed

The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage.

LRP6 LRP5

4.82e-05577219672307
Pubmed

Role and Regulation of p65/β-Catenin Association During Liver Injury and Regeneration: A "Complex" Relationship.

LRP6 LRP5

4.82e-05577228474571
Pubmed

Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation.

LRP6 LRP5

4.82e-05577216513652
Pubmed

Central role of pyrophosphate in acellular cementum formation.

ALPL ALPG

4.82e-05577222675556
Pubmed

Wnt/β-catenin signaling modulates corneal epithelium stratification via inhibition of Bmp4 during mouse development.

LRP6 LRP5

4.82e-05577226443636
Pubmed

Activation/Proliferation-associated Protein 2 (Caprin-2) Positively Regulates CDK14/Cyclin Y-mediated Lipoprotein Receptor-related Protein 5 and 6 (LRP5/6) Constitutive Phosphorylation.

LRP6 LRP5

4.82e-05577227821587
Pubmed

FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin.

FOXO1 LRP5

4.82e-05577222945629
InteractionDKKL1 interactions

MDN1 CELSR2 FAM20B LRP6 LRP5 APLP2

3.60e-06111756int:DKKL1
InteractionCNTN5 interactions

ACAD11 CNTN5

1.37e-052752int:CNTN5
GeneFamilyAlkaline phosphatases

ALPL ALPG

4.48e-0545021072
GeneFamilyLow density lipoprotein receptors

LRP6 LRP5

5.73e-0413502634
GeneFamilyCadherin related

CDH23 CDHR4

9.93e-041750224
GeneFamilyCD molecules|C2-set domain containing|Sialic acid binding Ig like lectins

CD33 SIGLEC1

2.71e-0328502745
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

JAK1 EPB41L1

8.44e-03505021293
GeneFamilyAAA ATPases

MDN1 CLPB

9.44e-0353502413
GeneFamilyLIM domain containing

MICALL1 NRAP

1.16e-02595021218
CoexpressionGSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP

FRY CAPN2 MYO16 EPB41L1 BAP1 ALPG

2.31e-05199756M8119
CoexpressionGSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_UP

RPL10L FOXO1 SETD2 GVINP1 PEPD JADE1

2.38e-05200756M4588
CoexpressionGSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_DN

A2M NRAP CELSR2 MYO16 SEZ6L SLC12A5

2.38e-05200756M3575
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

DOCK2 THEMIS CNTN5 SLC4A10 MYO16

8.25e-0616375519c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

A2M PLXDC1 SIGLEC1 PRLR SLC12A5

1.96e-051957554008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCell10x5'v1-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CKB A2M MYO1E SIGLEC1 SLC12A5

2.01e-05196755e0447ad2efb021b63c7fef000d39b6b21fbe6113
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CKB A2M MYO1E SIGLEC1 SLC12A5

2.01e-051967553bca88eede3dd7368715ced02e3bacd1e3e82cab
ToppCellCaecum-(6)_Macrophage-(61)_LYVE1_Macrophage|Caecum / shred on region, Cell_type, and subtype

A2M CD33 SIGLEC1 NLRC4 SLC12A5

2.11e-05198755e684c3934c163aef4d284b69435832d2c9614f2a
ToppCellCaecum-Macrophage-LYVE1_Macrophage|Caecum / Region, Cell class and subclass

A2M CD33 SIGLEC1 NLRC4 SLC12A5

2.11e-05198755a92c0cacb775aca6bbb302bd9e22c081a112a44d
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

MYO1E CAPN2 FAM20B ANKHD1 SEZ6L

2.16e-05199755fd1d1b95e01719e3d0a17d9d1f29717a47209d32
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PLXDC1 CD33 SIGLEC1 SLC12A5

2.16e-05199755e1066e638af83ba5e89c7cabb8ad00b6bcdee5f4
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Transverse / Region, Cell class and subclass

A2M SIGLEC1 PRLR NLRC4 SLC12A5

2.16e-05199755facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCellTransverse-(6)_Macrophage-(61)_LYVE1_Macrophage|Transverse / shred on region, Cell_type, and subtype

A2M SIGLEC1 PRLR NLRC4 SLC12A5

2.16e-05199755dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 PLXDC1 CD33 SIGLEC1 SLC12A5

2.16e-05199755ca0f6526ba0dcf8789dd3b583291519626427f2f
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

MYO1E CAPN2 FAM20B ANKHD1 SEZ6L

2.16e-0519975591882af9dc7265c9b419f4415cbcf656087a2ab3
ToppCellLung_Parenchyma-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CKB PCSK2 ERBB3 ABCA3 ALPL

2.21e-05200755c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CKB PCSK2 ERBB3 ABCA3 ALPL

2.21e-052007553ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCellParenchyma_Control_(B.)-Epithelial-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CKB PCSK2 ERBB3 ABCA3 ALPL

2.21e-052007559970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCellHippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Hippocampus / BrainAtlas - Mouse McCarroll V32

DOCK2 CD33 SIGLEC1 NLRC4

4.00e-05113754d5f183263cec9922d23cfd38ce9157eef4e58edb
ToppCellHippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

DOCK2 CD33 SIGLEC1 NLRC4

4.00e-051137541df80af2c690dac6bfd3dfd7d0052b66c1ae6ea5
ToppCellHippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

DOCK2 CD33 SIGLEC1 NLRC4

4.00e-05113754177414e4c859b047a4644664c596a3c22199cdf2
ToppCellHippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)|Hippocampus / BrainAtlas - Mouse McCarroll V32

DOCK2 CD33 SIGLEC1 NLRC4

4.00e-051137544b5f545dc02364c5d96a02b0acd68faf1ec4192b
ToppCellHippocampus-Hematopoietic-MACROPHAGE|Hippocampus / BrainAtlas - Mouse McCarroll V32

DOCK2 CD33 SIGLEC1 NLRC4

4.00e-05113754927d1071f0719b778f0c3d358c5f96a6ffac6645
ToppCellnormal_Pleural_Fluid-B_lymphocytes-Plasma_cells|normal_Pleural_Fluid / Location, Cell class and cell subclass

TAOK2 TXNDC15 IPO4 CCDC157

7.32e-051327544e37400ae7375e6986f060234c373194603346f8
ToppCellnormal_Pleural_Fluid-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

TAOK2 TXNDC15 IPO4 CCDC157

1.30e-04153754a156710217ef07c07a80ca6504fa0784d86380fa
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PHKG2 RNF123 CLP1 FAM83C

1.50e-04159754ba82d1f55dd77c4b2183981b76cab1480fba75ad
ToppCellMild-MAIT|Mild / Disease group and Cell class

A2M FRY SLC4A10 IPO4

1.58e-041617540c1a04485708d5302600cdc2d7dac1cb76b4033a
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR2 SUGCT SLC4A10 SIGLEC1

1.65e-041637541eec7f5e5fed05fa21d3f81db588f10605f08ea7
ToppCellBasal_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

CELSR2 PLXDC1 SUGCT GLIS3

1.85e-0416875448089fa2d4a0f31a72405717119b767a92571f01
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

FOXO1 PCSK2 ERBB3 MYO1E

1.90e-04169754a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT19 ABCA3 SUGCT PEPD

1.98e-0417175448fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCellwk_20-22-Mesenchymal-Chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PCSK2 GPR137C CPXM1 SEZ6L

1.98e-04171754d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCelldroplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT19 ABCA3 SUGCT PEPD

1.98e-0417175405fcc72df50a380a913821b5781d9621df37d328
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

A2M PCSK2 FRY MYO1E

1.98e-04171754e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 MIER3 NME7 PRLR

2.07e-04173754e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCellfacs-Large_Intestine-Proximal-3m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 MIER3 NME7 PRLR

2.07e-0417375499532bb768ee35fed939a377acb5215d3f8904bd
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

FOXO1 PCSK2 ERBB3 MYO1E

2.07e-041737546fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCellBronchial_Biopsy-Immune-Luminal_Macrophages|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DOCK2 CD33 SIGLEC1 NLRC4

2.17e-041757541cf99de391552d4f8dbe2ed5b01fc3b8adca61b6
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1|Hippocampus / BrainAtlas - Mouse McCarroll V32

THEMIS PLXDC1 CDH23

2.25e-04707538d6bdf2e773e894a0db39fdff1fafc2474e03fcf
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TAOK2 PHF2 LRP5 C2CD2L

2.31e-04178754c7e890cd02206c516cf1d7692ea7abc8ce746482
ToppCellB_cells-Naive_B_cells_|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

FOXO1 FRY MYO1E APLP2

2.31e-0417875471ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 THEMIS CNTN5 ALPL

2.36e-04179754b35a7f8115c997c390201da01d7cb10b10769aec
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Macrophage|lymph-node_spleen / Manually curated celltypes from each tissue

A2M NRAP SIGLEC1 EPB41L1

2.36e-04179754b4430f633711cecf793e8e76e766a66ff1eff473
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CKB NDST3 PCSK2 GLIS3

2.36e-041797548ce5000088b727783a0619baa16a2cd036d21f54
ToppCellCF-Myeloid-Alveolar_Macrophage|CF / Disease state, Lineage and Cell class

A2M PEPD SIGLEC1 EPB41L1

2.41e-041807546a7c3a3f3a16ca9f109047adaf36f6a2746d6ab9
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-plasma_cell-plasma_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERBB3 JADE1 PRLR ALPL

2.57e-041837540f6799e4f058bed546fe5759502430f4a19635da
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-plasma_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERBB3 JADE1 PRLR ALPL

2.57e-041837548ef5223e46f1fd81a856261248cc77e7c7e72ef6
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CKB PCSK2 ERBB3 ALPL

2.62e-041847547aa245b73e10fd73d292e822de6b72920aa12355
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CKB PCSK2 ERBB3 ALPL

2.68e-041857540149981d3818a6250f32c08456c28e7037c39d91
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

A2M FRY SUGCT GLIS3

2.79e-04187754464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PCSK2 MYO1E CPXM1 SEZ6L

2.79e-041877547e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

SUGCT GLIS3 PRLR EPB41L1

2.79e-04187754d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 CDH23 MYO16 SEZ6L

2.85e-04188754ee572246e0c2f41bdbc29a03edc67b831af95c09
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 CDH23 NLRC4 SEZ6L

2.85e-041887544e27ada1bda88811b73376c8a6136cbfc83bfdb9
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB PCSK2 PRLR SEZ6L

2.85e-04188754a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellControl-Myeloid-Monocytes|Control / group, cell type (main and fine annotations)

DOCK2 CDH23 NLRC4 SEZ6L

2.90e-041897543335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCellfacs-Pancreas-Endocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB PCSK2 PRLR SEZ6L

2.90e-04189754010fdd70e9d0e21b856306a29ff877776a480319
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

A2M FRY MYO1E NT5DC3

2.90e-041897546b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellT_cells-Effector_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

FOXO1 THEMIS PLXDC1 SLC4A10

2.96e-0419075413dc3a0aaa554f63eabac37726bd1f11b66fb3dd
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB PCSK2 PRLR SEZ6L

3.02e-041917543387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB PCSK2 PRLR SEZ6L

3.02e-04191754a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD33 SIGLEC1 NLRC4 SEZ6L

3.08e-0419275422f335e6e75a694cdccafe189b5ee7815ef28c03
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CKB PCSK2 ERBB3 ALPL

3.08e-041927543fc7a661ef39286abfd82ed8ab580011f01cb8fd
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M DOCK2 SIGLEC1 PRLR

3.08e-04192754935a4a36881a9fa4daa02cba96af07f6686ed8d6
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CKB PCSK2 ERBB3 ALPL

3.14e-041937544f4f430d7e1b65e19ca829f55ca93edeb6c1c85d
ToppCellPCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK2 CD33 SIGLEC1 NLRC4

3.14e-04193754c9e3fefa8d68d0e2b954f85ce37813185ff98d84
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

ERBB3 SUGCT LRP6 LRP5

3.14e-04193754503a979328c68b096680b71359a26f02fafdff35
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK2 THEMIS CD33 SLC4A10

3.14e-04193754afdf92ecace145407d57192dde5d0dac0bc37ee9
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLXDC1 CD33 SIGLEC1 SLC12A5

3.21e-04194754abce1e824ce2512741c313a5ec336d12f580b093
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLXDC1 CD33 SIGLEC1 SLC12A5

3.21e-041947546810586080cc893e3270b9c8bee2d95ed78e2893
ToppCellnormal_Lung-Epithelial_cells|normal_Lung / Location, Cell class and cell subclass

CKB ERBB3 ABCA3 ALPL

3.27e-041957547c90d887afde5c4d63352b5171be9987e2dfca58
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M DOCK2 CD33 SIGLEC1

3.27e-04195754c14d730dd5c94247bc09711eaa5a53bd5a5957be
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK2 KLHL5 LRP5 APLP2

3.27e-041957547f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M DOCK2 CD33 SIGLEC1

3.27e-04195754028622b234551b185977fbee10c06851a45456a5
ToppCellControl-Epithelial|Control / Disease state, Lineage and Cell class

CKB ERBB3 ABCA3 ALPL

3.27e-041957541798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK2 ABCA3 PRLR ALPL

3.33e-041967547e5addaa844e66f8160e05858c341866a80aed23
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK2 FRY SLC4A10 SLC12A5

3.33e-04196754676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell(7)_Epithelial-B_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PCSK2 ERBB3 ABCA3 ALPL

3.33e-04196754345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CKB A2M MYO1E SIGLEC1

3.33e-04196754bd2c2de103e28b65ea537c22f71225cb0deef1e0
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CKB A2M MYO1E SIGLEC1

3.33e-04196754072a4150ae521c6589b0f7cd60e975fb33715bf4
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CKB ERBB3 ABCA3 ALPL

3.33e-04196754784459f9f3614ead947aeb61a873dfd4cbe50641
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PLXDC1 SIGLEC1 PRLR SLC12A5

3.33e-04196754e8c4eeb4b6c6d9bccca2adb942d4cfbaab39636c
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M DOCK2 CD33 SIGLEC1

3.40e-04197754759f26753f76af3ae8d8527c4d221206245a3d45
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

A2M PLXDC1 NEK10 MYO16

3.40e-04197754e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

DOCK2 CD33 SIGLEC1 NLRC4

3.40e-04197754a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M DOCK2 CD33 SIGLEC1

3.40e-041977541c0024049db2d2c817a7f503de235b9630b24e33
ToppCellwk_20-22-Epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CKB ERBB3 NEK10 CDHR4

3.40e-04197754468071c1911cdf8e8806a78dbceb95379e28ae91
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M DOCK2 CD33 SIGLEC1

3.40e-04197754b72dc02b76a782f08eb1350ce131b072caec1ab0
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK2 ABCA3 PRLR ALPL

3.40e-04197754bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD33 PEPD CDH23 APLP2

3.40e-04197754280804810041783f1b7704914b62ffefbb0d88f6
ToppCellNS-critical-LOC-Myeloid-Macrophage|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

A2M CD33 PEPD SIGLEC1

3.40e-041977545fb0696376a5501b7c87e0f2f5e4fff3da2903f2
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 CD33 SIGLEC1 NLRC4

3.46e-04198754ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellsevere-Myeloid-CD14_Monocytes_3|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CD33 CAPN2 PEPD APLP2

3.46e-04198754374d7a24e00cd3f435ca980123ab3c6a441c9ad5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRY CNTN5 SLC4A10 SLC12A5

3.46e-041987548ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellMonocytes-Phagocytic_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

MYO1E APLP2 SIGLEC1 NLRC4

3.46e-0419875409009cc966bf1503c3b15dfa079a6c5f6ad1f507
ToppCellIPF-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

A2M FOXO1 MDN1 MYO1E

3.46e-04198754b8bd1ba268480f54451648e01631b615a3401144
ToppCellCOVID-19-Epithelial-AT2,_AT1_cells|COVID-19 / Condition, Lineage and Cell class

ERBB3 ABCA3 LRP6 ALPL

3.46e-041987547e6f089e71e70190ff8486341ab06719d7741467
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK2 FRY SLC4A10 SLC12A5

3.46e-041987540ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellwk_20-22-Hematologic-Myeloid-SPP1+_Mac|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PLXDC1 CD33 SIGLEC1 SLC12A5

3.53e-041997547c19f1b1f4369edd035ca9cdcf4e653771fc4648
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

A2M CD33 APLP2 SIGLEC1

3.53e-04199754b827dd8a249f904a0ff930a6c4d3b00fb7bc6fb1
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERBB3 CELSR2 LRP6 EPB41L1

3.53e-041997545d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCelldistal-1-Epithelial|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CKB ERBB3 ABCA3 ALPL

3.53e-041997549086dbb60863c3da2cc5d0a310f28596a01c52ca
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TAOK2 OXSM NLRC4 C2CD2L

3.53e-041997546dc446a5d183b01bdf227e45bd88d0b3d8b1c56a
Drugiodoacetamide

CKB A2M ERVK-6 CNTN5 CAPN2 PEPD OXSM ALPL

1.62e-07181768CID000003727
DrugCarbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; PC3; HT_HG-U133A

PMPCA SUGCT CAPN2 FAM20B LRP6 EPB41L1 C2CD2L

4.31e-061977677138_DN
Drugmagnesium

TAOK2 CKB RPL10L ERVK-6 PHKG2 CLPB MYO1E KCNJ4 PEPD OXSM SIGLEC1 CLP1 NME7 MYLK2 ALPL ALPG

6.21e-0613257616CID000000888
DiseaseLeukemia, Myelocytic, Acute

JAK1 FOXO1 SETD2 CD33 CAPN2

7.59e-05173745C0023467
Diseaseosteonecrosis (biomarker_via_orthology)

A2M LRP5

1.29e-047742DOID:10159 (biomarker_via_orthology)
Diseasecomplement C1q tumor necrosis factor-related protein 1 measurement

CELSR2 CDH23

4.03e-0412742EFO_0801493
Diseasegranulins measurement

CELSR2 CDH23

4.03e-0412742EFO_0008141
Diseasemonocyte percentage of leukocytes

JAK1 FOXO1 KLHL5 SETD2 PMPCA PEPD CDH23 MYO16

4.88e-04731748EFO_0007989
Diseasemalignant pleural mesothelioma (is_marker_for)

SETD2 BAP1

5.54e-0414742DOID:7474 (is_marker_for)
DiseaseFEV/FEC ratio

RPL10L FOXO1 PHF2 ERBB3 ABCA3 CNTN5 GLIS3 CDH23 MYO16 CDHR4

9.59e-0412287410EFO_0004713
Diseaselymphocyte count

DOCK2 JAK1 SETD2 ERBB3 PLXDC1 CD33 CNTN5 PEPD GLIS3 CDH23 SIGLEC1

1.02e-0314647411EFO_0004587
Diseasehydrocephalus (implicated_via_orthology)

CELSR2 NME7

1.03e-0319742DOID:10908 (implicated_via_orthology)
Diseasecentral corneal thickness

FOXO1 ACAD11 GLIS3 CPXM1 NT5DC3

1.09e-03309745EFO_0005213
Diseaseprogranulin measurement

CELSR2 CDH23

1.39e-0322742EFO_0004625
DiseaseNasopharyngeal carcinoma

ERBB3 BAP1

1.39e-0322742C2931822
Diseasechronotype measurement

PCSK2 RNF123 PMPCA KCNJ4 CNTN5 PRLR MYO16 SLC12A5

1.63e-03882748EFO_0008328
Diseasemonocyte count

FOXO1 KLHL5 SETD2 MYO1E CD33 CNTN5 GLIS3 CDH23 MYO16 MYLK2

1.65e-0313207410EFO_0005091
DiseaseNeurodevelopmental Disorders

PHF2 SETD2 ZC3H4

1.67e-0393743C1535926
Diseasesocial interaction measurement

PHF2 SLC4A10 CLP1

1.72e-0394743EFO_0009592
Diseasepallidum volume

MYLK2 ALPL

1.79e-0325742EFO_0006933
Diseaseinflammatory bowel disease (implicated_via_orthology)

THEMIS EPB41L1

1.79e-0325742DOID:0050589 (implicated_via_orthology)
Diseaseeye morphology measurement

FRY ADAM5 GLIS3 CDH23

2.23e-03218744EFO_0007858
Diseasemyeloid white cell count

SETD2 PMPCA MYO1E CD33 CNTN5 PEPD GLIS3 CDH23

2.38e-03937748EFO_0007988

Protein segments in the cluster

PeptideGeneStartEntry
SAMGLGYEDIDEIAP

SUGCT

146

Q9HAC7
LEEEDVNGYVMPDTH

ERBB3

1151

P21860
DGHLVPPTERSYMEE

ADAM5

396

Q6NVV9
ISGVPIELMDGDAAY

GVINP1

1446

Q7Z2Y8
HELGEPEVRYVAGMH

CPXM1

346

Q96SM3
PGSVLEDEHQGMVHY

ABCA3

1636

Q99758
MERIGLATAGEPYHD

BAP1

211

Q92560
IDPDEGEAGRLEYTM

CELSR2

206

Q9HCU4
DMVALLEHYDHVPGD

CCDC157

51

Q569K6
YSLEGPGVEAFHVDM

CDH23

2546

Q9H251
LLGSVVGTDMDYPHD

CDHR4

461

A6H8M9
PDTGNMEVLHLYGSE

ACAD11

471

Q709F0
EMHGPEGLRVGFYES

A2M

696

P01023
NDGVMGEYEPKIEVH

CNTN5

291

O94779
FALEHGIPTDMGYAV

NDST3

406

O95803
GMVLTVEPGIYFIDH

PEPD

406

P12955
VEEFVEGGPLDLFMH

JAK1

666

P23458
IVHEIDEDSPLYGMG

KCNJ4

261

P48050
YGTISHGIVEVDPML

APLP2

721

Q06481
MGEGAAVLVLEEYEH

OXSM

276

Q9NWU1
YRGMTPGEAEIHFLE

EPB41L1

261

Q9H4G0
SEGEMEEPTVDHYQL

TCTE1

216

Q5JU00
DHRGEIYVPELGMSF

MDN1

1841

Q9NU22
TGGIHMEEAPETYIP

NLRC4

631

Q9NPP4
GMVHLLPGDELYLED

NUDT19

301

A8MXV4
GEDARHEYTMTLGLP

NRAP

1241

Q86VF7
HPYIMTVGCVAGDEE

CKB

66

P12277
DDSEPVYIEMLGHAA

MYO16

1406

Q9Y6X6
SGAAPTVEMDEELHY

CD33

326

P20138
HVEDISGEEYIVFGM

GPR137C

291

Q8N3F9
HVVEFGLDYPEGMAV

LRP5

711

O75197
YIVMELIEGAPLGEH

NEK10

601

Q6ZWH5
TPHEIVLFMEYIEGG

MYLK2

351

Q9H1R3
LEHVVEFGLDYPEGM

LRP6

696

O75581
DQYIPEEDIHGEMDT

MICALL1

676

Q8N3F8
HHPGVTDYMDRLVDE

MIER3

346

Q7Z3K6
VAVLEGPMYAVGGHD

KLHL5

556

Q96PQ7
CSMDETHPGYGKEVD

PHKG2

201

P15735
GLFEPGDMKYEIHRD

ALPG

286

P10696
HNVDYLLGLFEPGDM

ALPL

281

P05186
ETEGLHCEYVAEPVM

ERVK-6

126

Q7LDI9
ETEGLHCEYVAEPVM

ERVK-7

126

P63130
DDLGEGDVHSMVYPP

FOXO1

336

Q12778
LDHEVEGGRGDEQYM

DOCK2

1136

Q92608
GPAATMAVELHYEEG

C2CD2L

396

O14523
LDVDYMTSHVRGGPE

FAM83C

76

Q9BQN1
LPAYGEDGALEHERM

GLIS3

226

Q8NEA6
NEMGHTPLDYAREGE

CLPB

296

Q9H078
VIGEHGDEIQGYVME

FRY

1896

Q5TBA9
VQHILMPDDEGEGEL

FBXO30

351

Q8TB52
MHTIGFGIYEVPEEL

CAPN2

426

P17655
EYDAMLLEHAGEAIP

IPO4

826

Q8TEX9
LLFYPGDGSVEMHDV

NME7

26

Q9Y5B8
GLADGTPIDMDHPYV

SLC12A5

401

Q9H2X9
FPLGGHMVSDEYEQL

RPL10L

46

Q96L21
YTPDRMVLAGVGVEH

PMPCA

246

Q10713
LTIYDGDEVMPHILG

SEZ6L

681

Q9BYH1
GYMEEHGFTEPILVP

PHF2

116

O75151
HKEELDGAGGEEYPM

TMEM183BP

121

Q1AE95
PDEEVIEMYEGSHVP

NT5DC3

181

Q86UY8
EEEEAEPYMHRAGTL

TAOK2

331

Q9UL54
MNHAIETEEGLGIEY

JADE1

186

Q6IE81
GYTPLMEAAREGHEE

ANKHD1

471

Q8IWZ3
GTMGALYIERPADVE

CLP1

161

Q92989
LPLYMEGGFVEVIHD

THEMIS

426

Q8N1K5
HKEELDGAGGEEYPM

TMEM183A

121

Q8IXX5
FGPVHSMEELPGYEE

RNF123

881

Q5XPI4
VYPEETPELGAVMHA

FAM20B

76

O75063
MEDEGTVQLPLEGHY

SLC4A10

1061

Q6U841
AVYLGEEELLHDPMG

TXNDC15

56

Q96J42
REGETLMHECPDYIT

PRLR

66

P16471
RLEIHGAMLEDEGVY

SIGLEC1

1051

Q9BZZ2
LEHEAEMDLGTPTYD

SETD2

2431

Q9BYW2
EMEPGLLGDAEDYGH

ZC3H4

706

Q9UPT8
YAEVEPSGHEKEGFM

PLXDC1

481

Q8IUK5
FIGDYIGMEEHPELQ

MYO1E

741

Q12965
VTIGIMDDGIDYLHP

PCSK2

161

P16519