Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

1.78e-07431419GO:0004984
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR12D3 OR2W1 OR7G1 FZD10 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

8.82e-068844110GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR12D3 OR2W1 OR7G1 FZD10 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 CNTFR LILRB4 OR1D2

1.11e-0513534112GO:0004888
GeneOntologyMolecularFunctionodorant binding

OR12D3 OR12D2 OR12D1 OR6N2

1.32e-04127414GO:0005549
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

8.67e-08432399GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

1.62e-07465399GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

2.31e-07485399GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

4.42e-07524399GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

6.33e-07547399GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

1.06e-06582399GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

6.20e-06722399GO:0051606
GeneOntologyBiologicalProcesssensory perception

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

1.38e-041072399GO:0007600
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR12D3 OR2W1 OR7G1 FZD10 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

2.02e-0413953910GO:0007186
DomainOlfact_rcpt

OR12D3 OR2W1 OR7G1 OR12D2 OR6N2 OR51B6 OR1D2

1.49e-05393397IPR000725
DomainProC_N

NOXRED1 STEAP3

8.86e-057392IPR028939
DomainF420_oxidored

NOXRED1 STEAP3

8.86e-057392PF03807
DomainGPCR_Rhodpsn_7TM

OR12D3 OR2W1 OR7G1 OR12D2 OR6N2 OR51B6 OR1D2

4.19e-04670397IPR017452
Domain7tm_1

OR12D3 OR2W1 OR7G1 OR12D2 OR6N2 OR51B6 OR1D2

4.46e-04677397PF00001
DomainG_PROTEIN_RECEP_F1_1

OR12D3 OR2W1 OR7G1 OR12D2 OR6N2 OR51B6 OR1D2

4.78e-04685397PS00237
DomainG_PROTEIN_RECEP_F1_2

OR12D3 OR2W1 OR7G1 OR12D2 OR6N2 OR51B6 OR1D2

5.04e-04691397PS50262
DomainGPCR_Rhodpsn

OR12D3 OR2W1 OR7G1 OR12D2 OR6N2 OR51B6 OR1D2

5.08e-04692397IPR000276
DomainCytokine_IL1-like

ADARB1 FGF19

2.56e-0336392IPR008996
DomainF-box-like

FBXO15 FBXW5

3.80e-0344392PF12937
DomainFBOX

FBXO15 FBXW5

5.27e-0352392SM00256
DomainF-box

FBXO15 FBXW5

8.62e-0367392PF00646
DomainFBOX

FBXO15 FBXW5

9.90e-0372392PS50181
DomainF-box_dom

FBXO15 FBXW5

1.07e-0275392IPR001810
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR12D3 OR2W1 OR7G1 OR12D2 OR6N2 OR51B6 OR51J1 OR1D2

1.36e-06417298M4072
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR12D3 OR2W1 OR7G1 OR12D2 OR6N2 OR51B6 OR1D2

1.07e-05389297M14091
PathwayREACTOME_SENSORY_PERCEPTION

OR12D3 OR2W1 OR7G1 OR12D2 OR6N2 OR51B6 OR51J1 OR1D2

3.03e-05636298M41834
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR2W1 OR7G1 OR1D2

3.91e-0470293MM14984
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

1.95e-1034041911875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

1.95e-1034041911802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

2.11e-1034341932295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR12D3 OR2W1 OR7G1 OR12D2 OR12D1 OR6N2 OR51B6 OR51J1 OR1D2

2.28e-1034641914611657
Pubmed

Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex.

OR12D3 OR12D2 OR12D1

4.31e-071341314506126
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR2W1 OR7G1 OR12D2 OR12D1

1.80e-067441415081110
Pubmed

Personal receptor repertoires: olfaction as a model.

OR12D2 OR12D1 OR51J1

1.25e-053841322908908
Pubmed

Novel function of beta-arrestin2 in the nucleus of mature spermatozoa.

RCC1 OR1D2

2.84e-05741216820410
Pubmed

The human olfactory receptor gene family.

OR12D3 OR2W1 OR7G1 OR12D2 OR6N2 OR1D2

3.90e-0554141614983052
Pubmed

Common variation contributes to the genetic architecture of social communication traits.

OR12D3 OR2W1

6.07e-051041224047820
Pubmed

Complex transcription and splicing of odorant receptor genes.

OR12D3 OR12D2

7.41e-051141212637542
Pubmed

Early molecular events during retinoic acid induced differentiation of neuromesodermal progenitors.

NT5E FGF19

8.88e-051241227793834
Pubmed

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

OR51B6 OR51J1

1.41e-041541211121057
Pubmed

The ULK1-FBXW5-SEC23B nexus controls autophagy.

FBXO15 FBXW5

2.54e-042041230596474
Pubmed

Foxg1 deletion impairs the development of the epithalamus.

FZD10 FGF19

4.67e-042741229394901
Pubmed

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.

ZMYM3 BRWD1

5.39e-042941221834987
Pubmed

The DNA sequence and analysis of human chromosome 6.

OR12D3 OR2W1 TBC1D22B OR12D2 LRP11

7.93e-0462241514574404
Pubmed

Novel Cul3 binding proteins function to remodel E3 ligase complexes.

FBXW5 BRWD1

1.03e-034041225011449
Pubmed

A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis.

FBXO15 BRWD1

1.08e-034141223509962
Pubmed

A family of mammalian F-box proteins.

FBXO15 FBXW5

1.13e-034241210531037
Pubmed

High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.

OR12D3 OR2W1 OR12D2

1.16e-0317541319851445
Cytoband6p22.2-p21.31

OR12D2 OR12D1

7.77e-0654126p22.2-p21.31
CytobandEnsembl 112 genes in cytogenetic band chr6p22

OR12D3 OR2W1 OR12D2 OR12D1

3.60e-04378414chr6p22
Cytoband19p13.2

OR7G1 ZNF560 ZNF700

1.14e-0322941319p13.2
GeneFamilyOlfactory receptors, family 12

OR12D3 OR12D2 OR12D1

6.08e-093343160
GeneFamilyOlfactory receptors, family 51

OR51B6 OR51J1

3.09e-0344342164

Protein segments in the cluster

PeptideGeneStartEntry
FCGAYFTFAISHEGH

RCC1

246

P18754
TLSANGYFHLHTRFC

PCDHB1

171

Q9Y5F3
YSTGGCLHTCSRYHF

LRP11

301

Q86VZ4
GALLFCGFIIYDTHS

TMBIM4

186

Q9HC24
GTYRCFSSHGFSHYL

LILRB4

191

Q8NHJ6
HGYIHIGSFSFSVLS

KIAA1109

66

Q2LD37
RGFFHSACGSLYAAV

SLC43A1

456

O75387
LIFGGYDHSHFSGSL

CTSE

231

P14091
LHLSFSHSGYQFASC

FBXW5

96

Q969U6
GHGACFSQAYFIHTL

OR51B6

91

Q9H340
YSSLHGFILLGFSNH

OR2W1

6

Q9Y3N9
SCAAGHVFGPLYSHL

OR51J1

116

Q9H342
HLYTSGPHGLSSCFL

FGF19

46

O95750
SFLGCISQLHFFHSL

OR12D2

91

P58182
TSHGYHLFCALLTGF

PAQR6

221

Q6TCH4
HLFCALLTGFLFASH

PAQR6

226

Q6TCH4
YFSSIILGSLYHGDH

ADARB1

581

P78563
SQHYFLFIGTLSCHP

RICTOR

656

Q6R327
SFLGCITQLHFFHFL

OR12D3

91

Q9UGF7
SFLGCISQLHFFHFL

OR12D1

91

P0DN82
CGCHLSVFSLFYGTA

OR7G1

241

Q8NGA0
GCLLQTYFFHSLGAS

OR6N2

96

Q8NGY6
EYGCHGHLRFFLCSL

FZD10

76

Q9ULW2
YLCSASNLFGTDHLH

IGSF10

1721

Q6WRI0
YTHFLSSFTCGLAGA

SLC25A30

201

Q5SVS4
LHVDLHSGGVFYLCG

FBXO15

356

Q8NCQ5
LHGLELGHSGLYACF

CNTFR

76

P26992
FACTDSHGHLLIFGF

BRWD1

531

Q9NSI6
LFLGTYICSGSLIHH

PRSS46P

61

E5RG02
FLDYFQTSHLGHSGL

SLFN13

701

Q68D06
DHLTHLYCASFGISL

NOXRED1

331

Q6NXP6
CASHLGAVSLFYGTL

OR1D2

241

P34982
LTHYHSLASFTFGCG

SESN1

206

Q9Y6P5
GFSHFHLYVCAAFLI

TBC1D22B

436

Q9NU19
PSYHHGSCLLSVFNL

PKDCC

426

Q504Y2
ISLSFHLGKLCHGLY

PPP4R4

311

Q6NUP7
GSHCHGSFSLIFLSL

NT5E

551

P21589
FCGKAFHSFSLYLIH

ZNF700

226

Q9H0M5
GLLSFFCAALHALYS

STEAP3

306

Q658P3
ASHLASHGFFCLRFT

TEX30

51

Q5JUR7
LNYGSSLCFHGRTFS

ZNF544

251

Q6NX49
GIHLSCHYCHSLFSG

ZMYM3

586

Q14202
HCGKAFISYPSLFGH

ZNF560

436

Q96MR9