Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransition metal ion binding

RNF8 EHMT1 ZNF343 FLG ADAMTS3 RNF207 RPTN GLI2 PRDM2

9.58e-051189339GO:0046914
GeneOntologyMolecularFunctionhistone H3K9 methyltransferase activity

EHMT1 PRDM2

2.04e-0413332GO:0046974
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF343 ZNF384 ZNF41 GLI1 GLI2 ZNF175 GLI3 PRDM2 ZNF837

3.51e-041412339GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF343 ZNF384 ZNF41 GLI1 GLI2 ZNF175 GLI3 PRDM2 ZNF837

4.48e-041459339GO:0000977
GeneOntologyMolecularFunctionzinc ion binding

RNF8 EHMT1 ZNF343 ADAMTS3 RNF207 GLI2 PRDM2

5.31e-04891337GO:0008270
GeneOntologyBiologicalProcessnotochord regression

GLI1 GLI2

2.33e-062322GO:0060032
GeneOntologyBiologicalProcesssmoothened signaling pathway involved in ventral spinal cord interneuron specification

GLI2 GLI3

6.99e-063322GO:0021775
GeneOntologyBiologicalProcesssmoothened signaling pathway involved in spinal cord motor neuron cell fate specification

GLI2 GLI3

6.99e-063322GO:0021776
GeneOntologyBiologicalProcesssmoothened signaling pathway involved in ventral spinal cord patterning

GLI2 GLI3

6.99e-063322GO:0021910
GeneOntologyBiologicalProcesspositive regulation of delayed rectifier potassium channel activity

AKAP6 RNF207

1.40e-054322GO:1902261
GeneOntologyBiologicalProcessproximal/distal pattern formation

GLI1 GLI2 GLI3

2.54e-0537323GO:0009954
GeneOntologyBiologicalProcessventral midline development

GLI1 GLI2

3.48e-056322GO:0007418
GeneOntologyBiologicalProcesssmoothened signaling pathway involved in dorsal/ventral neural tube patterning

GLI2 GLI3

4.87e-057322GO:0060831
GeneOntologyBiologicalProcesscell fate specification involved in pattern specification

GLI2 GLI3

6.49e-058322GO:0060573
GeneOntologyBiologicalProcessventral spinal cord interneuron specification

GLI2 GLI3

6.49e-058322GO:0021521
GeneOntologyBiologicalProcesshindgut morphogenesis

GLI2 GLI3

8.34e-059322GO:0007442
GeneOntologyBiologicalProcesspositive regulation of cation channel activity

AKAP6 RNF207 EDNRA

8.89e-0556323GO:2001259
GeneOntologyBiologicalProcessdigestive tract morphogenesis

GLI1 GLI2 GLI3

1.04e-0459323GO:0048546
GeneOntologyBiologicalProcesshindgut development

GLI2 GLI3

1.04e-0410322GO:0061525
GeneOntologyBiologicalProcessendocrine system development

BMP5 GLI1 GLI2 EDNRA

1.08e-04161324GO:0035270
GeneOntologyBiologicalProcessspinal cord motor neuron cell fate specification

GLI2 GLI3

1.27e-0411322GO:0021520
GeneOntologyBiologicalProcesspositive regulation of voltage-gated potassium channel activity

AKAP6 RNF207

1.27e-0411322GO:1903818
GeneOntologyBiologicalProcessheart development

AKAP6 BMP5 RNF207 GLI1 GLI2 GLI3 EDNRA

1.32e-04757327GO:0007507
GeneOntologyBiologicalProcesspattern specification process

BMP5 RNF207 GLI1 GLI2 GLI3 EDNRA

1.38e-04526326GO:0007389
GeneOntologyBiologicalProcessventral spinal cord interneuron fate commitment

GLI2 GLI3

1.52e-0412322GO:0060579
GeneOntologyBiologicalProcesscell fate commitment involved in pattern specification

GLI2 GLI3

1.52e-0412322GO:0060581
GeneOntologyBiologicalProcessnotochord morphogenesis

GLI1 GLI2

1.52e-0412322GO:0048570
GeneOntologyBiologicalProcessembryonic organ morphogenesis

RNF207 GLI1 GLI2 GLI3 EDNRA

1.91e-04351325GO:0048562
GeneOntologyBiologicalProcessembryonic organ development

BMP5 RNF207 GLI1 GLI2 GLI3 EDNRA

1.96e-04561326GO:0048568
GeneOntologyBiologicalProcessventral spinal cord interneuron differentiation

GLI2 GLI3

2.10e-0414322GO:0021514
GeneOntologyBiologicalProcesspositive regulation of potassium ion transmembrane transporter activity

AKAP6 RNF207

4.35e-0420322GO:1901018
GeneOntologyBiologicalProcessanatomical structure regression

GLI1 GLI2

4.35e-0420322GO:0060033
GeneOntologyBiologicalProcessspinal cord dorsal/ventral patterning

GLI2 GLI3

4.35e-0420322GO:0021513
GeneOntologyBiologicalProcessepithelial tube morphogenesis

BMP5 RNF207 GLI2 GLI3 EDNRA

4.42e-04421325GO:0060562
GeneOntologyBiologicalProcesspositive regulation of ion transmembrane transporter activity

AKAP6 RNF207 EDNRA

4.53e-0497323GO:0032414
GeneOntologyBiologicalProcessregulation of delayed rectifier potassium channel activity

AKAP6 RNF207

4.81e-0421322GO:1902259
GeneOntologyBiologicalProcessspinal cord patterning

GLI2 GLI3

5.28e-0422322GO:0021511
GeneOntologyBiologicalProcessregulation of smoothened signaling pathway

GLI1 GLI2 GLI3

5.71e-04105323GO:0008589
GeneOntologyBiologicalProcessdorsal/ventral pattern formation

GLI1 GLI2 GLI3

6.03e-04107323GO:0009953
GeneOntologyBiologicalProcesspositive regulation of transporter activity

AKAP6 RNF207 EDNRA

6.03e-04107323GO:0032411
GeneOntologyBiologicalProcessnotochord development

GLI1 GLI2

6.30e-0424322GO:0030903
GeneOntologyBiologicalProcessdorsal/ventral neural tube patterning

GLI2 GLI3

6.84e-0425322GO:0021904
GeneOntologyBiologicalProcessembryonic morphogenesis

BMP5 RNF207 GLI1 GLI2 GLI3 EDNRA

7.02e-04713326GO:0048598
GeneOntologyBiologicalProcessregionalization

RNF207 GLI1 GLI2 GLI3 EDNRA

7.86e-04478325GO:0003002
GeneOntologyBiologicalProcessnegative regulation of chondrocyte differentiation

GLI2 GLI3

7.99e-0427322GO:0032331
GeneOntologyBiologicalProcessmorphogenesis of an epithelial fold

BMP5 GLI2

9.22e-0429322GO:0060571
GeneOntologyBiologicalProcessepidermal cell differentiation

FLG EXPH5 GLI1 GLI2

9.34e-04284324GO:0009913
GeneOntologyBiologicalProcessear development

BMP5 GLI2 GLI3 EDNRA

9.46e-04285324GO:0043583
GeneOntologyBiologicalProcessaxon guidance

MYOT GLI2 GLI3 EDNRA

9.46e-04285324GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

MYOT GLI2 GLI3 EDNRA

9.59e-04286324GO:0097485
GeneOntologyBiologicalProcessregulation of cation channel activity

AKAP6 RNF207 EDNRA

1.26e-03138323GO:2001257
GeneOntologyBiologicalProcessembryo development

EHMT1 BMP5 ADAMTS3 RNF207 GLI1 GLI2 GLI3 EDNRA

1.27e-031437328GO:0009790
GeneOntologyBiologicalProcesspharyngeal system development

BMP5 EDNRA

1.27e-0334322GO:0060037
GeneOntologyBiologicalProcessembryonic digestive tract development

GLI2 GLI3

1.34e-0335322GO:0048566
GeneOntologyBiologicalProcessregulation of organ growth

AKAP6 ANKRD62 GLI1

1.40e-03143323GO:0046620
GeneOntologyBiologicalProcessnegative regulation of cartilage development

GLI2 GLI3

1.42e-0336322GO:0061037
GeneOntologyBiologicalProcessepithelium development

FLG BMP5 RNF207 EXPH5 GLI1 GLI2 GLI3 EDNRA

1.46e-031469328GO:0060429
GeneOntologyBiologicalProcesscardiac muscle tissue development

AKAP6 BMP5 GLI1 EDNRA

1.57e-03327324GO:0048738
GeneOntologyBiologicalProcessodontogenesis

GLI2 GLI3 EDNRA

1.63e-03151323GO:0042476
GeneOntologyBiologicalProcessdigestive tract development

GLI1 GLI2 GLI3

1.66e-03152323GO:0048565
GeneOntologyBiologicalProcessspinal cord motor neuron differentiation

GLI2 GLI3

1.84e-0341322GO:0021522
GeneOntologyBiologicalProcessregulation of membrane repolarization

AKAP6 RNF207

1.84e-0341322GO:0060306
GeneOntologyBiologicalProcessinterstrand cross-link repair

RNF8 MCM9

1.93e-0342322GO:0036297
GeneOntologyBiologicalProcessneuron fate specification

GLI2 GLI3

1.93e-0342322GO:0048665
GeneOntologyBiologicalProcesspositive regulation of potassium ion transmembrane transport

AKAP6 RNF207

1.93e-0342322GO:1901381
GeneOntologyBiologicalProcessnegative regulation of smoothened signaling pathway

GLI2 GLI3

1.93e-0342322GO:0045879
GeneOntologyBiologicalProcessepithelial cell differentiation

FLG BMP5 EXPH5 GLI1 GLI2 EDNRA

1.96e-03870326GO:0030855
GeneOntologyBiologicalProcessstriated muscle tissue development

AKAP6 BMP5 GLI1 EDNRA

1.99e-03349324GO:0014706
GeneOntologyBiologicalProcessin utero embryonic development

BMP5 ADAMTS3 GLI2 GLI3 EDNRA

2.09e-03596325GO:0001701
GeneOntologyBiologicalProcessdigestive system development

GLI1 GLI2 GLI3

2.18e-03167323GO:0055123
GeneOntologyBiologicalProcessneural tube patterning

GLI2 GLI3

2.21e-0345322GO:0021532
GeneOntologyBiologicalProcesspituitary gland development

GLI1 GLI2

2.21e-0345322GO:0021983
GeneOntologyBiologicalProcesspositive regulation of cation transmembrane transport

AKAP6 RNF207 EDNRA

2.45e-03174323GO:1904064
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

BMP5 RNF207 GLI2 GLI3 EDNRA

2.46e-03619325GO:0002009
GeneOntologyBiologicalProcessdevelopmental growth

AKAP6 ANKRD62 GLI1 GLI2 GLI3 EDNRA

2.47e-03911326GO:0048589
GeneOntologyBiologicalProcesspositive regulation of release of sequestered calcium ion into cytosol

AKAP6 EDNRA

2.52e-0348322GO:0051281
GeneOntologyBiologicalProcessprotein kinase A signaling

AKAP6 EDNRA

2.52e-0348322GO:0010737
GeneOntologyBiologicalProcesscerebellar cortex morphogenesis

GLI1 GLI2

2.52e-0348322GO:0021696
GeneOntologyBiologicalProcesssmoothened signaling pathway

GLI1 GLI2 GLI3

2.53e-03176323GO:0007224
GeneOntologyBiologicalProcessgland morphogenesis

GLI1 GLI2 GLI3

2.61e-03178323GO:0022612
GeneOntologyCellularComponentGLI-SUFU complex

GLI1 GLI2 GLI3

1.30e-084323GO:1990788
GeneOntologyCellularComponentciliary tip

GLI1 GLI2 GLI3

5.38e-0548323GO:0097542
GeneOntologyCellularComponentciliary base

GLI1 GLI2 GLI3

8.55e-0556323GO:0097546
MousePhenoabnormal basisphenoid bone morphology

ADAMTS3 GLI2 GLI3 EDNRA

2.48e-0657244MP:0000106
MousePhenoabnormal fibrous joint morphology

EHMT1 BMP5 GLI2 GLI3 EDNRA

2.86e-06135245MP:0030878
MousePhenowide sagittal suture

GLI3 EDNRA

8.47e-063242MP:0030353
MousePhenoabnormal ear position

BMP5 GLI3 EDNRA

1.42e-0528243MP:0000023
MousePhenoabnormal sphenoid bone morphology

ADAMTS3 GLI2 GLI3 EDNRA

1.92e-0595244MP:0000104
MousePhenoabnormal right lung accessory lobe morphology

GLI2 GLI3

2.82e-055242MP:0009571
MousePhenoabnormal joint morphology

EHMT1 BMP5 ADAMTS3 GLI2 GLI3 EDNRA

4.40e-05397246MP:0002932
MousePhenoabnormal basicranium morphology

ADAMTS3 GLI2 GLI3 EDNRA

5.29e-05123244MP:0010029
MousePhenoabnormal ear shape

BMP5 EDNRA

5.90e-057242MP:0000022
MousePhenoshort ulna

BMP5 GLI2 GLI3

6.43e-0546243MP:0004359
MousePhenoabnormal palatine bone morphology

GLI2 GLI3 EDNRA

6.43e-0546243MP:0005249
MousePhenodecreased ulna size

BMP5 GLI2 GLI3

6.43e-0546243MP:0030900
MousePhenomalocclusion

EHMT1 PEAK1 EDNRA

6.86e-0547243MP:0000120
MousePhenoshort humerus

BMP5 GLI2 GLI3

7.31e-0548243MP:0004351
MousePhenoabnormal lambdoid suture morphology

GLI3 EDNRA

7.86e-058242MP:0003841
MousePhenoabnormal temporomandibular joint morphology

GLI2 EDNRA

7.86e-058242MP:0011210
MousePhenoectopic ovary

BMP5 GLI3

7.86e-058242MP:0011727
MousePhenoabnormal fibula morphology

BMP5 GLI2 GLI3

8.77e-0551243MP:0002187
MousePhenoabnormal facial morphology

TRPM6 EHMT1 BMP5 PEAK1 ADAMTS3 GLI2 GLI3 EDNRA

9.00e-05910248MP:0003743
MousePhenomisaligned teeth

EHMT1 PEAK1 EDNRA

9.30e-0552243MP:0030540
MousePhenoabnormal maxilla morphology

BMP5 GLI2 GLI3 EDNRA

9.78e-05144244MP:0000455
MousePhenoabsent tympanic ring

GLI2 EDNRA

1.01e-049242MP:0003138
MousePhenosmall mandibular condyloid process

GLI2 EDNRA

1.01e-049242MP:0030258
MousePhenoabnormal metopic suture morphology

EHMT1 GLI3

1.26e-0410242MP:0003842
MousePhenoabnormal ovary topology

BMP5 GLI3

1.26e-0410242MP:0020491
MousePhenoabnormal tooth morphology

EHMT1 PEAK1 GLI2 GLI3 EDNRA

1.76e-04318245MP:0002100
MousePhenoabnormal dental arch morphology

EHMT1 PEAK1 GLI2 GLI3 EDNRA

1.78e-04319245MP:0030254
MousePhenoabnormal intervertebral disk morphology

BMP5 GLI2 GLI3

1.98e-0467243MP:0004173
MousePhenoabnormal cranial suture morphology

EHMT1 GLI3 EDNRA

1.98e-0467243MP:0002835
MousePhenoabnormal vertebral arch morphology

TRPM6 BMP5 ADAMTS3 GLI3

2.03e-04174244MP:0004599
MousePhenoabnormal jaw morphology

EHMT1 BMP5 PEAK1 GLI2 GLI3 EDNRA

2.17e-04530246MP:0000454
MousePhenoabnormal craniofacial suture morphology

EHMT1 GLI3 EDNRA

2.26e-0470243MP:0030229
MousePhenoabnormal symphysis morphology

BMP5 GLI2 GLI3

2.35e-0471243MP:0030877
MousePhenoabnormal sagittal suture morphology

GLI3 EDNRA

2.54e-0414242MP:0003843
MousePhenocraniofacial phenotype

AKAP6 TRPM6 EHMT1 BMP5 PEAK1 ADAMTS3 GLI2 GLI3 EDNRA

2.75e-041372249MP:0005382
MousePhenoabnormal craniofacial morphology

AKAP6 TRPM6 EHMT1 BMP5 PEAK1 ADAMTS3 GLI2 GLI3 EDNRA

2.75e-041372249MP:0000428
MousePhenoabnormal cranium morphology

EHMT1 BMP5 PEAK1 ADAMTS3 GLI2 GLI3 EDNRA

3.17e-04813247MP:0000438
MousePhenoabnormal craniofacial bone morphology

EHMT1 BMP5 PEAK1 ADAMTS3 GLI2 GLI3 EDNRA

3.52e-04827247MP:0002116
MousePhenoabnormal angiogenesis

BMP5 PEAK1 ADAMTS3 GLI3 EDNRA

3.64e-04372245MP:0000260
MousePhenoabnormal mandibular condyloid process morphology

GLI2 EDNRA

3.78e-0417242MP:0004595
MousePhenoabnormal head morphology

TRPM6 EHMT1 BMP5 PEAK1 ADAMTS3 GLI2 GLI3 EDNRA

3.81e-041120248MP:0000432
MousePhenoabnormal ulna morphology

BMP5 GLI2 GLI3

3.87e-0484243MP:0005108
MousePhenoabnormal viscerocranium morphology

EHMT1 BMP5 PEAK1 GLI2 GLI3 EDNRA

3.97e-04593246MP:0005274
MousePhenoabnormal cartilaginous joint morphology

BMP5 GLI2 GLI3

4.00e-0485243MP:0030875
MousePhenobowed radius

GLI2 GLI3

4.25e-0418242MP:0004374
MousePhenoabnormal orbit morphology

GLI3 EDNRA

4.25e-0418242MP:0010030
MousePhenolowered ear position

BMP5 EDNRA

4.25e-0418242MP:0000024
MousePhenoabnormal axial skeleton morphology

TRPM6 EHMT1 BMP5 PEAK1 TOPORS ADAMTS3 GLI2 GLI3 EDNRA

4.34e-041458249MP:0002114
MousePhenobasisphenoid bone foramen

ADAMTS3 GLI3

4.75e-0419242MP:0004463
MousePhenoabnormal forelimb stylopod morphology

BMP5 GLI2 GLI3

5.05e-0492243MP:0003854
MousePhenoabnormal humerus morphology

BMP5 GLI2 GLI3

5.05e-0492243MP:0005296
MousePhenoabnormal middle ear morphology

ADAMTS3 GLI2 EDNRA

5.05e-0492243MP:0000049
MousePhenoreduced cerebellar foliation

GLI2 GLI3

5.27e-0420242MP:0009719
MousePhenoabnormal optic chiasm morphology

ADAMTS3 GLI3

5.27e-0420242MP:0009770
MousePhenoshort fibula

GLI2 GLI3

5.27e-0420242MP:0002765
MousePhenoabnormal forelimb zeugopod morphology

BMP5 GLI2 GLI3

6.83e-04102243MP:0003855
MousePhenoabnormal mandibular ramus morphology

GLI2 EDNRA

6.99e-0423242MP:0010150
MousePhenodecreased lung weight

GLI2 GLI3

6.99e-0423242MP:0005631
MousePhenoshort facial bone

BMP5 GLI2 EDNRA

7.23e-04104243MP:0030384
MousePhenoabnormal mouth morphology

EHMT1 PEAK1 ADAMTS3 GLI2 GLI3 EDNRA

7.60e-04670246MP:0000452
MousePhenowide cranial sutures

GLI3 EDNRA

7.62e-0424242MP:0030029
MousePhenosmall mandible

BMP5 GLI2 EDNRA

9.92e-04116243MP:0004592
MousePhenoabnormal palatine bone horizontal plate morphology

GLI2 GLI3

1.04e-0328242MP:0004537
MousePhenoabnormal neurocranium morphology

ADAMTS3 GLI2 GLI3 EDNRA

1.05e-03269244MP:0000074
MousePhenoabnormal ear morphology

BMP5 ADAMTS3 GLI2 GLI3 EDNRA

1.05e-03470245MP:0002102
MousePhenoabnormal outer ear morphology

BMP5 GLI3 EDNRA

1.07e-03119243MP:0002177
MousePhenoabnormal laryngeal cartilage morphology

BMP5 GLI3

1.11e-0329242MP:0002256
MousePhenospontaneous chromosome breakage

RNF8 MCM9

1.11e-0329242MP:0004029
MousePhenoshort sternum

GLI2 GLI3

1.11e-0329242MP:0004321
MousePhenoshort femur

BMP5 GLI2 GLI3

1.29e-03127243MP:0003109
MousePhenoneoplasm

RNF8 PEAK1 TOPORS ADAMTS3 PRDM2 MCM9

1.34e-03747246MP:0002006
MousePhenodecreased fibroblast proliferation

RNF8 TOPORS MCM9

1.35e-03129243MP:0011704
MousePhenodecreased femur size

BMP5 GLI2 GLI3

1.38e-03130243MP:0030825
MousePhenoabnormal lung lobe morphology

GLI2 GLI3

1.44e-0333242MP:0010975
MousePhenoabnormal tympanic ring morphology

GLI2 EDNRA

1.44e-0333242MP:0000030
MousePhenoabnormal artery development

BMP5 ADAMTS3 EDNRA

1.47e-03133243MP:0003410
MousePhenoshort snout

TRPM6 BMP5 EDNRA

1.57e-03136243MP:0000445
MousePhenoincreased gland tumor incidence

RNF8 PRDM2 MCM9

1.67e-03139243MP:0010288
MousePhenoabnormal hyoid bone morphology

BMP5 EDNRA

1.72e-0336242MP:0003056
MousePhenoabnormal vertebral column morphology

TRPM6 BMP5 TOPORS ADAMTS3 GLI2 GLI3

1.75e-03787246MP:0004703
MousePhenoincreased tumor incidence

RNF8 TOPORS ADAMTS3 PRDM2 MCM9

1.80e-03530245MP:0002020
MousePhenosmall snout

TRPM6 BMP5 EDNRA

1.85e-03144243MP:0030190
MousePhenoabnormal vascular development

BMP5 PEAK1 ADAMTS3 GLI3 EDNRA

1.98e-03542245MP:0000259
MousePhenoshort maxilla

BMP5 GLI2

2.01e-0339242MP:0000097
MousePhenoabnormal palate morphology

ADAMTS3 GLI2 GLI3 EDNRA

2.02e-03321244MP:0003755
MousePhenoabnormal vertebrae morphology

TRPM6 BMP5 ADAMTS3 GLI2 GLI3

2.05e-03546245MP:0000137
Domain-

ZNF343 ZNF384 ZNF41 GLI1 GLI2 ZNF175 GLI3 PRDM2 ZNF837

1.85e-066793393.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

ZNF343 ZNF384 ZNF41 GLI1 GLI2 ZNF175 GLI3 PRDM2 ZNF837

2.22e-06694339IPR013087
DomainZINC_FINGER_C2H2_2

ZNF343 ZNF384 ZNF41 GLI1 GLI2 ZNF175 GLI3 PRDM2 ZNF837

5.47e-06775339PS50157
DomainZINC_FINGER_C2H2_1

ZNF343 ZNF384 ZNF41 GLI1 GLI2 ZNF175 GLI3 PRDM2 ZNF837

5.59e-06777339PS00028
DomainZnf_C2H2-like

ZNF343 ZNF384 ZNF41 GLI1 GLI2 ZNF175 GLI3 PRDM2 ZNF837

6.80e-06796339IPR015880
DomainZnf_C2H2

ZNF343 ZNF384 ZNF41 GLI1 GLI2 ZNF175 GLI3 PRDM2 ZNF837

7.45e-06805339IPR007087
DomainZnF_C2H2

ZNF343 ZNF384 ZNF41 GLI1 GLI2 ZNF175 GLI3 PRDM2 ZNF837

7.67e-06808339SM00355
Domainzf-C2H2

ZNF343 ZNF384 ZNF41 GLI1 GLI2 ZNF175 PRDM2 ZNF837

2.10e-05693338PF00096
DomainS100_CABP

FLG RPTN

1.03e-0327332PS00303
DomainS_100

FLG RPTN

1.03e-0327332PF01023
DomainS_100

FLG RPTN

1.11e-0328332SM01394
DomainS100_Ca-bd_sub

FLG RPTN

1.11e-0328332IPR013787
DomainS100/CaBP-9k_CS

FLG RPTN

1.11e-0328332IPR001751
DomainSET

EHMT1 PRDM2

2.38e-0341332PF00856
DomainZnf_RING_CS

RNF8 TOPORS RNF207

2.94e-03163333IPR017907
DomainSET

EHMT1 PRDM2

2.98e-0346332SM00317
DomainZnf_C3HC4_RING-type

RNF8 TOPORS RNF207

3.42e-03172333IPR018957
DomainSET_dom

EHMT1 PRDM2

3.52e-0350332IPR001214
DomainSET

EHMT1 PRDM2

3.52e-0350332PS50280
Domainzf-C3HC4

RNF8 TOPORS RNF207

7.04e-03223333PF00097
DomainAnk

EHMT1 ANKRD62 ABTB2

7.48e-03228333PF00023
Domain-

RNF8 TOPORS RNF207 EXPH5

7.77e-034493343.30.40.10
DomainZnf_RING/FYVE/PHD

RNF8 TOPORS RNF207 EXPH5

8.38e-03459334IPR013083
Domain-

EHMT1 ANKRD62 ABTB2

9.41e-032483331.25.40.20
DomainANK

EHMT1 ANKRD62 ABTB2

9.72e-03251333SM00248
DomainANK_REPEAT

EHMT1 ANKRD62 ABTB2

9.93e-03253333PS50088
DomainAnkyrin_rpt-contain_dom

EHMT1 ANKRD62 ABTB2

1.00e-02254333IPR020683
DomainANK_REP_REGION

EHMT1 ANKRD62 ABTB2

1.00e-02254333PS50297
DomainAnkyrin_rpt

EHMT1 ANKRD62 ABTB2

1.09e-02262333IPR002110
DomainZF_RING_1

RNF8 TOPORS RNF207

1.45e-02291333PS00518
DomainZF_RING_2

RNF8 TOPORS RNF207

1.54e-02298333PS50089
DomainRING

RNF8 TOPORS RNF207

1.64e-02305333SM00184
PathwayREACTOME_GLI_PROTEINS_BIND_PROMOTERS_OF_HH_RESPONSIVE_GENES_TO_PROMOTE_TRANSCRIPTION

GLI1 GLI2 GLI3

1.72e-077253M27501
PathwayKEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY

GLI1 GLI2 GLI3

1.77e-0614253M47414
PathwayBIOCARTA_SHH_PATHWAY

GLI1 GLI2 GLI3

2.21e-0615253MM1498
PathwayKEGG_HEDGEHOG_SIGNALING_PATHWAY

BMP5 GLI1 GLI2 GLI3

2.65e-0656254M1053
PathwayWP_HEDGEHOG_SIGNALING_WP47

GLI1 GLI2 GLI3

2.72e-0616253M39675
PathwayBIOCARTA_SHH_PATHWAY

GLI1 GLI2 GLI3

2.72e-0616253M11792
PathwayWP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM

BMP5 GLI1 GLI2 GLI3

3.51e-0660254M40048
PathwayWP_HEDGEHOG_SIGNALING_PATHWAY

GLI1 GLI2 GLI3

7.42e-0622253MM15924
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY

GLI1 GLI2 GLI3

1.75e-0529253M47372
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY

GLI1 GLI2 GLI3

1.75e-0529253M47377
PathwayWP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1

GLI1 GLI2 GLI3

2.14e-0531253M39522
PathwayWP_HEDGEHOG_SIGNALING_WP4249

GLI1 GLI2 GLI3

5.80e-0543253M39706
PathwayPID_HEDGEHOG_GLI_PATHWAY

GLI1 GLI2 GLI3

8.08e-0548253M219
PathwayKEGG_BASAL_CELL_CARCINOMA

GLI1 GLI2 GLI3

1.22e-0455253M17807
PathwayREACTOME_HEDGEHOG_ON_STATE

GLI1 GLI2 GLI3

3.84e-0481253MM15225
PathwayREACTOME_HEDGEHOG_ON_STATE

GLI1 GLI2 GLI3

4.58e-0486253M27497
PathwayREACTOME_HEDGEHOG_OFF_STATE

GLI1 GLI2 GLI3

8.20e-04105253MM15206
PathwayREACTOME_HEDGEHOG_OFF_STATE

GLI1 GLI2 GLI3

1.01e-03113253M27471
PathwayWP_DOPAMINERGIC_NEUROGENESIS

GLI1 GLI2

1.27e-0330252M39580
PathwayWP_DOPAMINERGIC_NEUROGENESIS

GLI1 GLI2

1.27e-0330252MM15831
PathwayREACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT

GLI2 GLI3

1.36e-0331252M27805
PathwayWP_HAIR_FOLLICLE_DEVELOPMENT_ORGANOGENESIS_STAGE_2_OF_3

GLI1 GLI2

1.45e-0332252M40041
PathwayREACTOME_SIGNALING_BY_HEDGEHOG

GLI1 GLI2 GLI3

1.77e-03137253MM15182
PathwayREACTOME_SIGNALING_BY_HEDGEHOG

GLI1 GLI2 GLI3

2.29e-03150253M27440
PathwayWP_CILIOPATHIES

TOPORS GLI2 GLI3

4.07e-03184253M39880
Pubmed

Fuzzy modeling reveals a dynamic self-sustaining network of the GLI transcription factors controlling important metabolic regulators in adult mouse hepatocytes.

GLI1 GLI2 GLI3

7.78e-10333326010061
Pubmed

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene.

GLI1 GLI2 GLI3

7.78e-1033338387379
Pubmed

Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.

GLI1 GLI2 GLI3

7.78e-10333316571352
Pubmed

Gli family members are differentially expressed during the mitotic phase of spermatogenesis.

GLI1 GLI2 GLI3

7.78e-1033339178901
Pubmed

Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers.

GLI1 GLI2 GLI3

7.78e-1033338378770
Pubmed

Different expression patterns of Gli1-3 in mouse embryonic maxillofacial development.

GLI1 GLI2 GLI3

7.78e-10333322178118
Pubmed

Cloning and sequencing of the mouse Gli2 gene: localization to the Dominant hemimelia critical region.

GLI1 GLI2 GLI3

3.11e-0943339027508
Pubmed

Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina.

GLI1 GLI2 GLI3

3.11e-09433322281533
Pubmed

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.

GLI1 GLI2 GLI3

3.11e-0943339006072
Pubmed

Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.

GLI1 GLI2 GLI3

3.11e-09433327793025
Pubmed

Expression profile of Gli family members and Shh in normal and mutant mouse limb development.

GLI1 GLI2 GLI3

3.11e-0943339438426
Pubmed

Anorectal malformations caused by defects in sonic hedgehog signaling.

GLI1 GLI2 GLI3

3.11e-09433311485934
Pubmed

Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development.

GLI1 GLI2 GLI3

3.11e-0943338150204
Pubmed

Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1.

GLI1 GLI2 GLI3

3.11e-09433310531011
Pubmed

Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization.

BMP5 GLI1 GLI2 GLI3

7.04e-092433412403705
Pubmed

SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factors.

GLI1 GLI2 GLI3

7.77e-09533320711444
Pubmed

Functional compensation in Hedgehog signaling during mouse prostate development.

GLI1 GLI2 GLI3

7.77e-09533316707121
Pubmed

Identification of a suppressive mechanism for Hedgehog signaling through a novel interaction of Gli with 14-3-3.

GLI1 GLI2 GLI3

7.77e-09533319996099
Pubmed

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro.

GLI1 GLI2 GLI3

7.77e-0953339118802
Pubmed

Evidence for the involvement of the Gli gene family in embryonic mouse lung development.

GLI1 GLI2 GLI3

7.77e-0953339268579
Pubmed

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation.

GLI1 GLI2 GLI3

7.77e-09533316611981
Pubmed

Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning.

GLI1 GLI2 GLI3

7.77e-09533315315762
Pubmed

Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli.

GLI1 GLI2 GLI3

7.77e-09533310564661
Pubmed

Sonic hedgehog signals to multiple prostate stromal stem cells that replenish distinct stromal subtypes during regeneration.

GLI1 GLI2 GLI3

7.77e-09533324218555
Pubmed

Gli regulation by the opposing activities of fused and suppressor of fused.

GLI1 GLI2 GLI3

7.77e-09533310806483
Pubmed

p53 modulates the activity of the GLI1 oncogene through interactions with the shared coactivator TAF9.

GLI1 GLI2 GLI3

7.77e-09533326282181
Pubmed

Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma.

GLI1 GLI2 GLI3

7.77e-09533319593328
Pubmed

Gli1 is a target of Sonic hedgehog that induces ventral neural tube development.

GLI1 GLI2 GLI3

7.77e-0953339216996
Pubmed

Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling.

GLI1 GLI2 GLI3

7.77e-09533326120032
Pubmed

Expression pattern of Irx1 and Irx2 during mouse digit development.

GLI1 GLI2 GLI3

7.77e-09533311472848
Pubmed

Expression of the mouse Fgf15 gene is directly initiated by Sonic hedgehog signaling in the diencephalon and midbrain.

GLI1 GLI2 GLI3

7.77e-09533315614767
Pubmed

Nerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells.

GLI1 GLI2 GLI3

1.55e-08633321549329
Pubmed

Expression of sonic hedgehog signaling molecules in normal, hyperplastic and carcinomatous endometrium.

GLI1 GLI2 GLI3

1.55e-08633319432668
Pubmed

RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.

GLI1 GLI2 GLI3

1.55e-08633333895473
Pubmed

Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.

GLI1 GLI2 GLI3

1.55e-08633314681189
Pubmed

Titration of GLI3 repressor activity by sonic hedgehog signaling is critical for maintaining multiple adult neural stem cell and astrocyte functions.

GLI1 GLI2 GLI3

1.55e-08633324174682
Pubmed

Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling.

GLI1 GLI2 GLI3

1.55e-08633317202190
Pubmed

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function.

GLI1 GLI2 GLI3

1.55e-08633316254602
Pubmed

Coordinated translocation of mammalian Gli proteins and suppressor of fused to the primary cilium.

GLI1 GLI2 GLI3

1.55e-08633321209912
Pubmed

Targeted disruption of Sonic Hedgehog in the mouse adrenal leads to adrenocortical hypoplasia.

GLI1 GLI2 GLI3

1.55e-08633319536807
Pubmed

A novel gene, GliH1, with homology to the Gli zinc finger domain not required for mouse development.

GLI1 GLI2 GLI3

1.55e-08633312385751
Pubmed

Phosphorylation of Ci/Gli by Fused Family Kinases Promotes Hedgehog Signaling.

GLI1 GLI2 GLI3

1.55e-08633331279575
Pubmed

Irx1 and Irx2 expression in early lung development.

GLI1 GLI2 GLI3

1.55e-08633311472847
Pubmed

Physical and functional interactions between Zic and Gli proteins.

GLI1 GLI2 GLI3

1.55e-08633311238441
Pubmed

Hedgehog regulates Norrie disease protein to drive neural progenitor self-renewal.

GLI1 GLI2 GLI3

2.72e-08733323201751
Pubmed

FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine.

GLI1 GLI2 GLI3

2.72e-08733319049965
Pubmed

Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice.

GLI1 GLI2 GLI3

2.72e-0873339152005
Pubmed

A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus.

GLI1 GLI2 GLI3

2.72e-08733321653639
Pubmed

Differential activities of Sonic hedgehog mediated by Gli transcription factors define distinct neuronal subtypes in the dorsal thalamus.

GLI1 GLI2 GLI3

2.72e-08733314568100
Pubmed

Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line.

GLI1 GLI2 GLI3

2.72e-08733328799057
Pubmed

The GLI-Kruppel family of human genes.

GLI1 GLI2 GLI3

2.72e-0873332850480
Pubmed

Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus.

GLI1 GLI2 GLI3

2.72e-0873339731531
Pubmed

Analysis of the Sonic Hedgehog signaling pathway in normal and abnormal bladder development.

GLI1 GLI2 GLI3

2.72e-08733323308271
Pubmed

Sonic hedgehog regulates discrete populations of astrocytes in the adult mouse forebrain.

GLI1 GLI2 GLI3

2.72e-08733320943901
Pubmed

Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3.

GLI1 GLI2 GLI3

2.72e-08733312435627
Pubmed

Gli3-mediated repression of Hedgehog targets is required for normal mammary development.

GLI1 GLI2 GLI3

2.72e-08733316914490
Pubmed

Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube.

GLI1 GLI2 GLI3

4.34e-08833322265416
Pubmed

Expression of hedgehog signalling components in adult mouse testis.

GLI1 GLI2 GLI3

4.34e-08833316958114
Pubmed

Morphogenesis.

GLI1 GLI2 GLI3

4.34e-0883339988217
Pubmed

The transcription factor Gli3 promotes B cell development in fetal liver through repression of Shh.

GLI1 GLI2 GLI3

4.34e-08833328533268
Pubmed

Spatiotemporal expression of sonic hedgehog signalling molecules in the embryonic mesencephalic dopaminergic neurons.

GLI1 GLI2 GLI3

4.34e-08833334767969
Pubmed

Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1.

GLI1 GLI2 GLI3

4.34e-08833310529434
Pubmed

Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation.

GLI1 GLI2 GLI3

4.34e-08833312221011
Pubmed

Gli1 is not required for Pdgfralpha expression during mouse embryonic development.

GLI1 GLI2 GLI3

4.34e-08833315811134
Pubmed

GLI transcriptional repression is inert prior to Hedgehog pathway activation.

GLI1 GLI2 GLI3

4.34e-08833335145123
Pubmed

Unique functions of Sonic hedgehog signaling during external genitalia development.

GLI1 GLI2 GLI3

4.34e-08833311684660
Pubmed

Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity.

GLI1 GLI2 GLI3

4.34e-08833310631181
Pubmed

Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline.

GLI1 GLI2 GLI3

6.51e-08933327802276
Pubmed

Distinct expression patterns of Hedgehog signaling components in mouse gustatory system during postnatal tongue development and adult homeostasis.

GLI1 GLI2 GLI3

6.51e-08933338848388
Pubmed

Identification of GLI Mutations in Patients With Hirschsprung Disease That Disrupt Enteric Nervous System Development in Mice.

GLI1 GLI2 GLI3

6.51e-08933326261006
Pubmed

Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.

GLI1 GLI2 GLI3

6.51e-08933323249739
Pubmed

Sonic Hedgehog mediator Gli2 regulates bladder mesenchymal patterning.

GLI1 GLI2 GLI3

6.51e-08933318710724
Pubmed

Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia.

GLI1 GLI2 GLI3

6.51e-08933325083987
Pubmed

Opposing gradients of Gli repressor and activators mediate Shh signaling along the dorsoventral axis of the inner ear.

GLI1 GLI2 GLI3

6.51e-08933317395647
Pubmed

Gli3 null mice display glandular overgrowth of the developing stomach.

GLI1 GLI2 GLI3

6.51e-08933316247775
Pubmed

Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities.

GLI1 GLI2 GLI3

6.51e-08933315315763
Pubmed

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.

GLI1 GLI2 GLI3

6.51e-08933310725236
Pubmed

New Insights into Development of Female Reproductive Tract-Hedgehog-Signal Response in Wolffian Tissues Directly Contributes to Uterus Development.

GLI1 GLI2 GLI3

6.51e-08933333530552
Pubmed

The loss of Hh responsiveness by a non-ciliary Gli2 variant.

GLI1 GLI2 GLI3

6.51e-08933325834022
Pubmed

Regulation of Calvarial Osteogenesis by Concomitant De-repression of GLI3 and Activation of IHH Targets.

GLI1 GLI2 GLI3

6.51e-08933329311969
Pubmed

The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis.

GLI1 GLI2 GLI3

6.51e-08933311748155
Pubmed

The Shh signalling pathway in early tooth development.

GLI1 GLI2 GLI3

9.30e-081033310512189
Pubmed

Patched1 patterns Fibroblast growth factor 10 and Forkhead box F1 expression during pulmonary branch formation.

GLI1 GLI2 GLI3

9.30e-081033328939119
Pubmed

The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling.

GLI1 GLI2 GLI3

9.30e-081033319549984
Pubmed

Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation.

GLI1 GLI2 GLI3

9.30e-081033316284117
Pubmed

Increasing Sufu gene dosage reveals its unorthodox role in promoting polydactyly and medulloblastoma tumorigenesis.

GLI1 GLI2 GLI3

9.30e-081033338358805
Pubmed

CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA.

GLI1 GLI2 GLI3

9.30e-081033318298960
Pubmed

Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification.

GLI1 GLI2 GLI3

9.30e-081033312812795
Pubmed

Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development.

GLI1 GLI2 GLI3

9.30e-081033315496441
Pubmed

Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction.

GLI1 GLI2 GLI3

9.30e-081033314602680
Pubmed

Fusion of lung lobes and vessels in mouse embryos heterozygous for the forkhead box f1 targeted allele.

GLI1 GLI2 GLI3

9.30e-081033311943666
Pubmed

Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1.

GLI1 GLI2 GLI3

9.30e-08103339247260
Pubmed

Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling.

GLI1 GLI2 GLI3

9.30e-081033327849569
Pubmed

Synovial joint formation during mouse limb skeletogenesis: roles of Indian hedgehog signaling.

GLI1 GLI2 GLI3

9.30e-081033318083924
Pubmed

Gli1 can rescue the in vivo function of Gli2.

GLI1 GLI2 GLI3

9.30e-081033311748151
Pubmed

Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth.

GLI1 GLI2 GLI3

1.28e-071133315668330
Pubmed

Complementary Gli activity mediates early patterning of the mouse visual system.

GLI1 GLI2 GLI3

1.28e-071133316342201
Pubmed

GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis.

GLI1 GLI2 GLI3

1.28e-071133316396903
Pubmed

Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation.

GLI1 GLI2 GLI3

1.28e-071133336252002
Pubmed

Role of Indian hedgehog signaling in palatal osteogenesis.

GLI1 GLI2 GLI3

1.28e-071133321364421
InteractionZIC2 interactions

GLI1 GLI2 GLI3

3.20e-0539323int:ZIC2
InteractionSTK36 interactions

GLI1 GLI2 GLI3

4.93e-0545323int:STK36
InteractionZFP37 interactions

GLI1 GLI2 GLI3

6.38e-0549323int:ZFP37
InteractionZNF667 interactions

GLI1 GLI2 GLI3

8.07e-0553323int:ZNF667
InteractionZNF287 interactions

GLI1 GLI2 GLI3

1.17e-0460323int:ZNF287
InteractionLHX5 interactions

GLI1 GLI2

1.33e-0411322int:LHX5
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF343 ZNF384 ZNF41 GLI1 GLI2 ZNF175 GLI3 ZNF837

6.75e-0671827828
GeneFamilyEF-hand domain containing|S100 fused type protein family

FLG RPTN

4.49e-0572721350
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

EHMT1 PRDM2

1.17e-0334272487
GeneFamilyAnkyrin repeat domain containing

EHMT1 ANKRD62 ABTB2

5.46e-03242273403
GeneFamilyRing finger proteins

RNF8 TOPORS RNF207

7.77e-0327527358
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#3_top-relative-expression-ranked_1000

BMP5 ADAMTS3 ABTB2 EDNRA

3.27e-05118334gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k3
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200

BMP5 GLI1 GLI2 EDNRA

7.72e-05147334gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200

BMP5 GLI1 GLI2 EDNRA

9.01e-05153334gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500

ADAMTS3 GLI1 GLI2 EDNRA

1.76e-04182334gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500

BMP5 ADAMTS3 GLI1 GLI2 EDNRA

2.08e-04356335gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

BMP5 GLI1 GLI2 GLI3 EDNRA

2.22e-04361335gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500

BMP5 ADAMTS3 GLI1 GLI2 EDNRA

2.30e-04364335gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

BMP5 GLI1 GLI2 GLI3 EDNRA

2.58e-04373335gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000

ADAMTS3 GLI2 ABTB2 GLI3 EDNRA

2.71e-04377335gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k2
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000

BMP5 TOPORS GLI2 ZNF175 ABTB2 GLI3 EDNRA

2.74e-04849337gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_500

BMP5 ADAMTS3 ABTB2 GLI3 EDNRA

3.17e-04390335gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#1_top-relative-expression-ranked_500

BMP5 GLI1 GLI3

3.78e-0491333gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_1000

BMP5 ADAMTS3 EDNRA MCM9

4.22e-04229334gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k1
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMP5 ADAMTS3 GLI1 ZNF175

8.67e-06177334e65c0568dc5852108e9802273499bc7cf88fafab
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BMP5 GLI2 GLI3 EDNRA

1.08e-05187334a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

BMP5 PEAK1 GLI1 EDNRA

1.10e-051883343f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BMP5 ADAMTS3 GLI1 EDNRA

1.12e-051893343169476f98b7385706cb618c9ad64ae83a290ef0
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

ZNF343 ADAMTS3 GLI2 GLI3

1.15e-051903347dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellASK440-Mesenchymal-Fibroblast|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

BMP5 GLI2 GLI3 EDNRA

1.17e-05191334387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCellASK440-Mesenchymal|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

BMP5 GLI2 GLI3 EDNRA

1.17e-05191334f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMP5 GLI2 GLI3 EDNRA

1.19e-05192334d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BMP5 ADAMTS3 GLI2 EDNRA

1.22e-05193334fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BMP5 GLI1 GLI2 EDNRA

1.22e-05193334b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BMP5 GLI2 GLI3 EDNRA

1.24e-0519433435f132cc38ac133be01834ed0946188aa0757eb4
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BMP5 GLI2 GLI3 EDNRA

1.24e-05194334b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BMP5 GLI2 GLI3 EDNRA

1.27e-051953340e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellPCW_07-8.5-Mesenchymal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BMP5 GLI2 GLI3 EDNRA

1.29e-051963348e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BMP5 GLI2 GLI3 EDNRA

1.32e-0519733473a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BMP5 GLI2 GLI3 EDNRA

1.35e-0519833421cf4d81386761d09d0f6829c01c198e5524176d
ToppCellPCW_10-12-Mesenchymal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BMP5 GLI2 GLI3 EDNRA

1.37e-05199334a09292de4c4447b8eee55d401808e43b817321cc
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

BMP5 PEAK1 ADAMTS3 EDNRA

1.37e-0519933430d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

BMP5 GLI2 GLI3 EDNRA

1.37e-051993344bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

BMP5 GLI1 GLI2 EDNRA

1.40e-05200334ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Entopeduncular / BrainAtlas - Mouse McCarroll V32

BMP5 GLI1 EDNRA

8.18e-05114333108cc5b04cc7c59310eb55dc2c44ae2b8e0b05e4
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)|Hippocampus / BrainAtlas - Mouse McCarroll V32

GLI1 GLI2 GLI3

9.76e-051213338334a6b2ced1d6a4808458d6d4232d1b688ba28a
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

GLI1 GLI2 GLI3

9.76e-051213334b33eeed7b70da120133b14d42c104d2461d52dc
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

GLI1 GLI2 GLI3

9.76e-05121333a33e4ae0b0efb702db1b646ac0486e3b6ce48457
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-6|TCGA-Bladder / Sample_Type by Project: Shred V9

ANKRD62 FLG RPTN

1.13e-04127333d61b71572eab8a850ee8ce54323fb247525006e5
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADAMTS3 RNF207 GSG1L2

1.26e-04132333ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TRPM6 PEAK1 KLRC1

1.50e-04140333a88dbe7bf3e1419e360ab0b8cf24681d3424c3a7
ToppCellmild_COVID-19_(asymptomatic)-NK_CD56bright|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

FSIP2 KLRC1 ABTB2

1.88e-041513332470162f4b56bc505db166a6eb0fa54847759df8
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BMP5 GLI2 EDNRA

1.88e-0415133332d35906f4b2bd46b173e87f2dec972eb5da87b3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PEAK1 GSG1L2 GLI2

2.03e-0415533382e602f31981c6b48abff2a04b2ab5d26d4462a2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PEAK1 GSG1L2 GLI2

2.03e-04155333979c1d53b435a82c57d16707eed8ba7346326866
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ADAMTS3 ABTB2

2.11e-041573332c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

BMP5 PEAK1 EDNRA

2.23e-041603330293b244c063a62819690bf22bbc2681f8d15252
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYOT KLRC1 GLI1

2.23e-041603338e2b51d7b42e0b6e62641efdbbc73d31561d6a3e
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

BMP5 PEAK1 EDNRA

2.23e-041603333eaae86fa08f7651021316f8e5811bf48055591e
ToppCellnormal_Lung-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

ZNF384 EXPH5 ABTB2

2.27e-04161333283012858e575c70d09950de53da041509f59bfa
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF343 GLI2 EDNRA

2.27e-04161333a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF343 GLI2 EDNRA

2.27e-0416133308920a716f6ec62538e361211455a30ad726d7be
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AKAP6 TRPM6 ZNF384

2.52e-04167333774f3264318b002d0df5d06d41d645366038d0bf
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

TRPM6 RNF207 ABTB2

2.71e-04171333ce290930385cac35dbd21a5e91cf0f93cf3e99f8
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMP5 ADAMTS3 GLI1

2.80e-04173333f8e3dded726bb3a6c24bfedf8c6732bb46262308
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AKAP6 GLI2 EDNRA

2.90e-04175333d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AKAP6 GLI2 EDNRA

2.90e-04175333454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellNasal_Brush-Epithelial-Basal_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

BMP5 ADAMTS3 EDNRA

2.95e-04176333fc5787946f5a10056d326d070620575ae4081836
ToppCellNasal_Brush-Epithelial-Basal_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

BMP5 ADAMTS3 EDNRA

2.95e-041763335daaba0853afe7d20d4635169ccd4f96e735b938
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

BMP5 GLI2 EDNRA

2.99e-04177333cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

BMP5 GLI2 EDNRA

2.99e-04177333db222faaecbe5600da39277243c4e7e764eb63c9
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 BMP5 EDNRA

2.99e-04177333dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 BMP5 EDNRA

3.04e-04178333416f85e51f45ec7949451fd47611a84e33e87245
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 BMP5 EDNRA

3.09e-041793338da6863edc756540bb097cc7221c1408640d9bb4
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PEAK1 GLI1 EDNRA

3.09e-04179333948c2a01ec7a626c68281e6e796a9f0527a88591
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 BMP5 EDNRA

3.09e-04179333f39c13c99a07d009cc677e363ffe089089c64916
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BMP5 ADAMTS3 GLI2

3.15e-0418033308ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Dendritic_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS3 EXPH5 GLI3

3.15e-041803335b7d2336ed09d07f6b8dd91c1fa9c5ade633c104
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS3 EXPH5 GLI3

3.15e-04180333d33bb00f2b7d07dda9015cb8eafd742c2b2e9ace
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BMP5 ADAMTS3 GLI2

3.15e-041803339b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BMP5 ADAMTS3 GLI2

3.20e-041813339e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP5 PEAK1 EDNRA

3.25e-04182333dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP5 PEAK1 EDNRA

3.25e-04182333c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellPSB-critical-LOC-Epithelial-Squamous|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FLG RPTN ABTB2

3.30e-041833332cf798a2371c61322484ea16fdfae0acfa94f102
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLI1 GLI2 GLI3

3.30e-0418333399bb4ceb92f6467f2359a42ab2cff6df18825a30
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANKRD62 ADAMTS3 EXPH5

3.30e-041833331645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLI1 GLI2 ABTB2

3.30e-041833337eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellfacs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 BMP5 EDNRA

3.30e-041833338d45dff06a199b1369576657f7f9dc0249c5f841
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 GLI1 EDNRA

3.30e-041833338de4b616a06be03e1cb6ae6a9ce6bf06485629d3
ToppCellfacs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 BMP5 EDNRA

3.30e-04183333421265fa15d5a028cb567bb0904e670473ef102b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANKRD62 ADAMTS3 EXPH5

3.35e-0418433334e316ad8e7b8667cd8ad61397281802a252744f
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

BMP5 GLI1 GLI3

3.35e-04184333235890e8b424f4386b6ea52d173d20a00898df73
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMP5 GLI2 GLI3

3.35e-04184333c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMP5 GLI2 EDNRA

3.41e-041853337092436b4db90289516ed130ade596e3021cffaf
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLG RPTN ABTB2

3.41e-04185333f3fbc3096f85397a959cee17c3c4fcf2d511f3d5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMP5 GLI2 EDNRA

3.41e-04185333a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2|TCGA-Kidney / Sample_Type by Project: Shred V9

PEAK1 GLI2 EDNRA

3.46e-041863331e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

BMP5 RNF207 GLI1

3.46e-04186333cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

GLI2 GLI3 EDNRA

3.46e-04186333cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 BMP5 EDNRA

3.52e-04187333f1e9877d859369b862d4a559ec9ab9be74a67a96
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 BMP5 EDNRA

3.52e-041873333ffbd50b49059dcd3e23c5ac01901e4352142446
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

BMP5 GLI1 EDNRA

3.57e-04188333ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS3 GLI2 GLI3

3.57e-04188333ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 MYOT EDNRA

3.57e-04188333d534ed9870405a3c1075962308f72b460aed17bf
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

AKAP6 BMP5 GLI3

3.63e-04189333203c80030df08ae112f9ae4043709f455d87ce89
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMP5 GLI2 GLI3

3.63e-0418933371397e993a77d70b2eeede240bdfc7660b558987
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKAP6 GLI2 EDNRA

3.63e-041893332cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMP5 GLI2 GLI3

3.63e-041893334eea4759520c312bd17a681034d8074e47093d2b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BMP5 ADAMTS3 GLI2

3.63e-04189333a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BMP5 ADAMTS3 GLI2

3.63e-041893332a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ADAMTS3 ABTB2

3.63e-0418933390aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKAP6 GLI2 EDNRA

3.63e-04189333127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLI1 GLI2 ABTB2

3.63e-0418933345e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ADAMTS3 ABTB2

3.68e-041903334836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS3 GLI2 GLI3

3.68e-04190333efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMP5 GLI2 GLI3

3.74e-0419133339092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellBL-critical-LOC-Epithelial-Squamous|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FLG RPTN ABTB2

3.74e-041913333f9b8c4fb72ae6f3167b187e6715c4dcb3159f98
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

TOPORS RPTN GPRASP2

3.74e-04191333b5328733da3d3d77c4f6fc5e2ba2035f8898f172
ToppCellCOVID-19-kidney-vSMC/Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

AKAP6 GLI2 EDNRA

3.74e-04191333fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 MYOT EDNRA

3.74e-04191333f932980baa032748857cb367a55c37dd975c693e
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

GLI2 GLI3 EDNRA

3.74e-0419133378c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GLI2 GLI3 EDNRA

3.74e-041913337b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLI1 GLI2 ABTB2

3.74e-04191333b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BMP5 GLI2 EDNRA

3.74e-041913336688cee34beee4f151ac17fccbc9c26a9aad72e1
DrugJK184

GLI1 GLI2

1.15e-054322ctd:C525593
DrugSANT-1 compound

GLI1 GLI2

1.15e-054322ctd:C468919
Drug1,4-diaminocyclohexane

GLI1 GLI2

1.15e-054322ctd:C088969
DrugLDE225

GLI1 GLI2

1.91e-055322ctd:C561435
Diseaseprimary bacterial infectious disease (implicated_via_orthology)

GLI1 GLI2 GLI3

7.93e-089303DOID:0050338 (implicated_via_orthology)
DiseaseGastrointestinal Stromal Sarcoma

GLI1 GLI2 GLI3

1.49e-0547303C3179349
DiseaseGastrointestinal Stromal Tumors

GLI1 GLI2 GLI3

1.80e-0550303C0238198
Diseasepre-malignant neoplasm (biomarker_via_orthology)

GLI1 GLI3

1.35e-0417302DOID:0060071 (biomarker_via_orthology)
Diseaseurate measurement, bone density

AKAP6 TRPM6 FSIP2 PEAK1 GLI2

3.69e-04619305EFO_0003923, EFO_0004531
DiseaseCongenital small ears

BMP5 EDNRA

7.99e-0441302C0152423
DiseaseAcute Promyelocytic Leukemia

GLI1 GLI2

1.01e-0346302C0023487

Protein segments in the cluster

PeptideGeneStartEntry
RSNSNQNFHTHERER

ANKRD62

541

A6NC57
DQNNHNTDRSSHKDS

EDNRA

411

P25101
RHEQAQDSSRHSASQ

FLG

2766

P20930
HNNSSLNTRTQKARH

KLRC1

101

P26715
TEKQQAQNGSRHSQH

GSG1L2

236

A8MUP6
AFSNASDRAKHQNRT

GLI3

586

P10071
SDRAKHQNRTHSNEK

GLI3

591

P10071
RNSAHTLNQASSRSH

KIF12

216

Q96FN5
HTANAAHQRQNSSNN

FSIP2

361

Q5CZC0
GNVKTNANHSNNHRI

PEAK1

41

Q9H792
NANHSNNHRIRNTGN

PEAK1

46

Q9H792
HVSNQKSNSISQRHQ

EXPH5

1686

Q8NEV8
AFSNASDRAKHQNRT

GLI1

341

P08151
SDRAKHQNRTHSNEK

GLI1

346

P08151
NASDRAKHQNRTHSN

GLI2

546

P10070
ASQQQRSDLNHSEHH

ADAMTS3

336

O15072
RKNQNRNKSSSHQDS

BMP5

321

P22003
HANAAKHTQDSARVN

EHMT1

66

Q9H9B1
DKNSNSNHRRRTADA

PRDM2

1506

Q13029
TSRKHSAQHKNNRDD

MCM9

726

Q9NXL9
DTRQHSSAHSNQDKK

RSBN1L

826

Q6PCB5
THDDSRNNAASARNN

RNF207

566

Q6ZRF8
NKASHNRTRALQSHS

PNKD

31

Q8N490
HHEQKASNSSASQRS

RNF8

231

O76064
ESNTRSRHRAKHQTN

GPRASP2

251

Q96D09
KSNSQALNSSAQQHR

ABTB2

36

Q8N961
QESSSSSHHDAKNQQ

AKAP6

346

Q13023
NQRSNLSRHQRTHSS

ZNF837

401

Q96EG3
FSQKSNLSRHQRTHS

ZNF343

306

Q6P1L6
QLSNLQSHRRQHNKD

ZNF384

386

Q8TF68
KHQRHSSGNRNESAE

TRPM6

546

Q9BX84
TLNSHNHNRNSATKN

ZNF41

241

P51814
DSRSQSRSGHDQKNH

TOPORS

601

Q9NS56
QDRDSHHNQSERQDK

RPTN

176

Q6XPR3
NNRSNFNKHQTTHTR

ZNF175

681

Q9Y473
GAQDSQQHNSEHARL

MYOT

206

Q9UBF9