Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin protein ligase activity

CBLL1 TRAF6 TRIM75 MARCHF8 MARCHF2 NFX1 TRIM77 MARVELD3 TRIM27 ZNF598 MARCHF1

2.69e-073728011GO:0061630
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

CBLL1 TRAF6 TRIM75 MARCHF8 MARCHF2 NFX1 TRIM77 MARVELD3 TRIM27 ZNF598 MARCHF1

5.25e-073988011GO:0061659
GeneOntologyMolecularFunctionzinc ion binding

USP44 TRAF6 TIMP2 TRIM75 MARCHF8 ESR1 ESR2 MARCHF2 MMP23B NFX1 TRIM77 SKI TRIM27 MARCHF1 CXXC1

2.16e-068918015GO:0008270
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

CBLL1 TRAF6 TRIM75 MARCHF8 MARCHF2 NFX1 TRIM77 MARVELD3 TRIM27 ZNF598 MARCHF1

2.82e-064738011GO:0004842
GeneOntologyMolecularFunctiontransition metal ion binding

USP44 TRAF6 TIMP2 CYP4Z1 TRIM75 MARCHF8 ESR1 ESR2 MARCHF2 MMP23B NFX1 CYP4X1 TRIM77 SKI TRIM27 MARCHF1 CXXC1

3.78e-0611898017GO:0046914
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

CBLL1 TRAF6 TRIM75 MARCHF8 MARCHF2 NFX1 TRIM77 MARVELD3 TRIM27 ZNF598 MARCHF1

6.00e-065128011GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

CBLL1 TRAF6 TRIM75 MARCHF8 MARCHF2 NFX1 TRIM77 MARVELD3 TRIM27 ZNF598 MARCHF1

8.62e-065328011GO:0016755
GeneOntologyMolecularFunctionnuclear estrogen receptor activity

ESR1 ESR2

9.46e-054802GO:0030284
GeneOntologyMolecularFunctionanandamide 14,15 epoxidase activity

CYP4Z1 CYP4X1

2.35e-046802GO:0062189
GeneOntologyMolecularFunctionanandamide epoxidase activity

CYP4Z1 CYP4X1

2.35e-046802GO:0062186
GeneOntologyMolecularFunctionacyltransferase activity

CBLL1 TRAF6 TRIM75 MARCHF8 MARCHF2 NFX1 TRIM77 MARVELD3 TRIM27 ZNF598 MARCHF1

2.56e-047758011GO:0016746
GeneOntologyMolecularFunctionpore-forming activity

DEFA1 DEFA3

6.99e-0410802GO:0140911
GeneOntologyMolecularFunctionestrogen response element binding

ESR1 ESR2

8.52e-0411802GO:0034056
GeneOntologyBiologicalProcesspost-translational protein modification

CBLL1 USP44 CTU2 TRAF6 TRIM75 MARCHF8 MARCHF2 NFX1 TRIM77 MARVELD3 USP9Y TRIM27 ZNF598 MARCHF1 ZC3HAV1

1.63e-0510748115GO:0043687
GeneOntologyBiologicalProcessmotor neuron migration

CELSR1 CELSR3 CELSR2

2.57e-0515813GO:0097475
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

CBLL1 USP44 CTU2 TRAF6 TRIM75 MARCHF8 MARCHF2 NFX1 TRIM77 MARVELD3 USP9Y TRIM27 ZNF598 MARCHF1

3.49e-0510098114GO:0070647
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

CBLL1 USP44 CTU2 TRAF6 TRIM75 MARCHF8 MARCHF2 NFX1 TRIM77 MARVELD3 TRIM27 ZNF598 MARCHF1

4.22e-058938113GO:0032446
GeneOntologyBiologicalProcessdefense response to virus

DEFA1 DEFA3 USP44 TRAF6 MARCHF2 TRIM27 DICER1 ZC3HAV1

5.91e-05342818GO:0051607
GeneOntologyBiologicalProcessprotein ubiquitination

CBLL1 USP44 TRAF6 TRIM75 MARCHF8 MARCHF2 NFX1 TRIM77 MARVELD3 TRIM27 ZNF598 MARCHF1

7.35e-058118112GO:0016567
GeneOntologyBiologicalProcessestrogen receptor signaling pathway

DEFA1 DEFA3 ESR1 ESR2

7.44e-0557814GO:0030520
GeneOntologyBiologicalProcessneural tube development

CELSR1 TRAF6 SMO SKI WDPCP SEMA4C

1.44e-04202816GO:0021915
GeneOntologyBiologicalProcesscalcium activated phospholipid scrambling

ANO4 ANO3

1.51e-045812GO:0061588
GeneOntologyBiologicalProcesscalcium activated phosphatidylcholine scrambling

ANO4 ANO3

1.51e-045812GO:0061590
GeneOntologyBiologicalProcesscalcium activated galactosylceramide scrambling

ANO4 ANO3

1.51e-045812GO:0061591
GeneOntologyBiologicalProcessdisruption of plasma membrane integrity in another organism

DEFA1 DEFA3

2.26e-046812GO:0051673
GeneOntologyBiologicalProcessdisruption of cellular anatomical structure in another organism

DEFA1 DEFA3

2.26e-046812GO:0140975
GeneOntologyBiologicalProcessnon-canonical Wnt signaling pathway

CELSR1 CELSR3 CELSR2 FZD10

2.40e-0477814GO:0035567
GeneOntologyBiologicalProcessresponse to virus

DEFA1 DEFA3 USP44 TRAF6 MARCHF2 TRIM27 DICER1 ZC3HAV1

2.63e-04425818GO:0009615
GeneOntologyBiologicalProcessinnate immune response

DEFA1 IL34 DEFA3 USP44 TRAF6 ESR1 MARCHF2 UMOD TRIM77 TRIM27 IL18RAP NPLOC4 ZC3HAV1

3.13e-0410928113GO:0045087
GeneOntologyBiologicalProcessnegative regulation of MHC class II biosynthetic process

MARCHF8 NFX1

3.16e-047812GO:0045347
GeneOntologyBiologicalProcessdefense response to other organism

DEFA1 IL34 DEFA3 USP44 TRAF6 STAB2 ESR1 MARCHF2 UMOD TRIM77 TRIM27 IL18RAP DICER1 NPLOC4 ZC3HAV1

3.39e-0414078115GO:0098542
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen via MHC class II

TRAF6 MARCHF8 MARCHF1

3.79e-0436813GO:0002495
GeneOntologyBiologicalProcessSertoli cell proliferation

ESR1 ESR2

4.20e-048812GO:0060011
GeneOntologyBiologicalProcessantigen processing and presentation of peptide or polysaccharide antigen via MHC class II

TRAF6 MARCHF8 MARCHF1

4.46e-0438813GO:0002504
GeneOntologyBiologicalProcessdefense response to symbiont

DEFA1 IL34 DEFA3 USP44 TRAF6 ESR1 MARCHF2 UMOD TRIM77 TRIM27 IL18RAP DICER1 NPLOC4 ZC3HAV1

4.46e-0412868114GO:0140546
GeneOntologyBiologicalProcessnegative regulation of Schwann cell proliferation

SKI DICER1

5.39e-049812GO:0010626
GeneOntologyCellularComponentGolgi lumen

DEFA1 DEFA3 UMOD GPC5 MUC5AC

6.97e-05109825GO:0005796
HumanPhenoNeuroepithelial neoplasm

MMP23B SMO SKI DICER1 SDHB

4.48e-0592235HP:0030063
HumanPhenoNeuroectodermal neoplasm

MMP23B SMO SKI DICER1 SDHB

4.97e-0594235HP:0030061
HumanPhenoNervous tissue neoplasm

MMP23B SMO SKI DICER1 SDHB

4.97e-0594235HP:0030060
HumanPhenoMalignant neoplasm of the central nervous system

MMP23B SMO SKI DICER1 SDHB

6.39e-0599235HP:0100836
HumanPhenoNeoplasm of the central nervous system

MMP23B SMO SKI DICER1 WDPCP SDHB

1.03e-04178236HP:0100006
HumanPhenoDecreased urinary urate

UMOD MOCS1

1.16e-044232HP:0011935
HumanPhenoNeoplasm of the nervous system

MMP23B SMO SKI DICER1 WDPCP SDHB

1.70e-04195236HP:0004375
HumanPhenoPrimitive neuroectodermal tumor

MMP23B SKI DICER1 SDHB

2.01e-0467234HP:0030065
Domain-

CBLL1 USP44 TRAF6 MARCHF8 MARCHF2 ZFYVE21 SCAF11 TRIM77 TRIM27 ZNF598 MARCHF1 CXXC1

5.07e-0744981123.30.40.10
DomainZnf_RING/FYVE/PHD

CBLL1 USP44 TRAF6 MARCHF8 MARCHF2 ZFYVE21 SCAF11 TRIM77 TRIM27 ZNF598 MARCHF1 CXXC1

6.40e-074598112IPR013083
DomainZnf_RING

CBLL1 TRAF6 MARCHF8 MARCHF2 NFX1 SCAF11 TRIM77 TRIM27 ZNF598 MARCHF1

1.43e-063268110IPR001841
DomainMARCH-like

MARCHF8 MARCHF2 MARCHF1

4.33e-068813IPR033275
DomainGPCR_2_secretin-like

CELSR1 CELSR3 CELSR2 FZD10 SMO

6.13e-0660815IPR000832
DomainGPCR_2-like

CELSR1 CELSR3 CELSR2 FZD10 SMO

6.13e-0660815IPR017981
DomainG_PROTEIN_RECEP_F2_4

CELSR1 CELSR3 CELSR2 FZD10 SMO

6.66e-0661815PS50261
DomainEGF_LAM_2

CELSR1 STAB2 CELSR3 CELSR2

8.26e-0630814PS50027
DomainEGF_LAM_1

CELSR1 STAB2 CELSR3 CELSR2

8.26e-0630814PS01248
DomainRINGv

MARCHF8 MARCHF2 MARCHF1

1.26e-0511813PF12906
DomainGAIN_dom_N

CELSR1 CELSR3 CELSR2

1.26e-0511813IPR032471
DomainZF_RING_CH

MARCHF8 MARCHF2 MARCHF1

1.26e-0511813PS51292
DomainGAIN

CELSR1 CELSR3 CELSR2

1.26e-0511813PF16489
DomainEGF_CA

CELSR1 STAB2 CELSR3 CELSR2 SLIT3 UMOD

1.49e-05122816SM00179
DomainEGF_Lam

CELSR1 STAB2 CELSR3 CELSR2

1.55e-0535814SM00180
DomainEGF-like_Ca-bd_dom

CELSR1 STAB2 CELSR3 CELSR2 SLIT3 UMOD

1.64e-05124816IPR001881
DomainEGF

CELSR1 STAB2 CELSR3 CELSR2 SLIT3 UMOD

1.80e-05126816PF00008
DomainLAM_G_DOMAIN

CELSR1 CELSR3 CELSR2 SLIT3

2.17e-0538814PS50025
DomainLaminin_EGF

CELSR1 STAB2 CELSR3 CELSR2

2.17e-0538814IPR002049
DomainLaminin_G_2

CELSR1 CELSR3 CELSR2 SLIT3

2.66e-0540814PF02210
DomainLamG

CELSR1 CELSR3 CELSR2 SLIT3

3.91e-0544814SM00282
DomainZnf_RING-CH

MARCHF8 MARCHF2 MARCHF1

5.11e-0517813IPR011016
DomainRINGv

MARCHF8 MARCHF2 MARCHF1

5.11e-0517813SM00744
Domainzf-C3HC4

TRAF6 MARCHF8 MARCHF2 NFX1 TRIM77 TRIM27 MARCHF1

5.17e-05223817PF00097
DomainEGF-type_Asp/Asn_hydroxyl_site

CELSR1 CELSR3 CELSR2 SLIT3 UMOD

9.74e-05106815IPR000152
DomainZnf_C3HC4_RING-type

TRAF6 MARCHF8 MARCHF2 TRIM77 TRIM27 MARCHF1

1.02e-04172816IPR018957
DomainLaminin_G

CELSR1 CELSR3 CELSR2 SLIT3

1.17e-0458814IPR001791
DomainHormR

CELSR1 CELSR3 CELSR2

1.69e-0425813SM00008
DomainDefensin_propep

DEFA1 DEFA3

1.84e-045812PF00879
DomainAlpha-defensin

DEFA1 DEFA3

1.84e-045812IPR006081
DomainDefensin_1

DEFA1 DEFA3

1.84e-045812PF00323
DomainAlpha-defensin_pro

DEFA1 DEFA3

1.84e-045812IPR016327
DomainOest_rcpt/oest-rel_rcp

ESR1 ESR2

1.84e-045812IPR024178
DomainDEFENSIN

DEFA1 DEFA3

1.84e-045812PS00269
DomainDefensin_propep

DEFA1 DEFA3

1.84e-045812IPR002366
DomainHRM

CELSR1 CELSR3 CELSR2

2.38e-0428813PF02793
DomainZF_RING_1

CBLL1 TRAF6 NFX1 SCAF11 TRIM77 TRIM27 ZNF598

2.69e-04291817PS00518
DomainZF_RING_2

CBLL1 TRAF6 NFX1 SCAF11 TRIM77 TRIM27 ZNF598

3.11e-04298817PS50089
DomainRING

CBLL1 TRAF6 NFX1 SCAF11 TRIM77 TRIM27 ZNF598

3.58e-04305817SM00184
DomainConA-like_dom

CELSR1 CELSR3 CELSR2 SLIT3 TRIM77 TRIM27

3.79e-04219816IPR013320
DomainAnoct_dimer

ANO4 ANO3

3.85e-047812PF16178
DomainAnoct_dimer

ANO4 ANO3

3.85e-047812IPR032394
DomainGPS

CELSR1 CELSR3 CELSR2

4.27e-0434813SM00303
DomainGPS

CELSR1 CELSR3 CELSR2

4.65e-0435813PF01825
DomainLaminin_EGF

CELSR1 CELSR3 CELSR2

4.65e-0435813PF00053
DomainGPS

CELSR1 CELSR3 CELSR2

5.06e-0436813PS50221
DomainDefensin_beta/alpha

DEFA1 DEFA3

5.11e-048812IPR006080
DomainDEFSN

DEFA1 DEFA3

5.11e-048812SM00048
DomainGPS

CELSR1 CELSR3 CELSR2

5.49e-0437813IPR000203
DomainEGF_3

CELSR1 STAB2 CELSR3 CELSR2 SLIT3 UMOD

5.50e-04235816PS50026
DomainEGF

CELSR1 STAB2 CELSR3 CELSR2 SLIT3 UMOD

5.50e-04235816SM00181
DomainGrowth_fac_rcpt_

CELSR1 STAB2 CELSR2 SLIT3 UMOD

5.86e-04156815IPR009030
DomainR3H

NFX1 NKRF

6.56e-049812SM00393
DomainG_PROTEIN_RECEP_F2_1

CELSR1 CELSR3 CELSR2

6.92e-0440813PS00649
DomainGPCR_2_extracellular_dom

CELSR1 CELSR3 CELSR2

6.92e-0440813IPR001879
DomainG_PROTEIN_RECEP_F2_3

CELSR1 CELSR3 CELSR2

6.92e-0440813PS50227
DomainZnf_RING_CS

CBLL1 TRAF6 SCAF11 TRIM77 TRIM27

7.15e-04163815IPR017907
DomainEGF-like_dom

CELSR1 STAB2 CELSR3 CELSR2 SLIT3 UMOD

7.45e-04249816IPR000742
Domain-

CELSR1 CELSR3 CELSR2 SLIT3

7.75e-04958142.60.120.200
DomainAnoctamin

ANO4 ANO3

8.17e-0410812PF04547
DomainAnoctamin

ANO4 ANO3

8.17e-0410812IPR007632
DomainEGF_1

CELSR1 STAB2 CELSR3 CELSR2 SLIT3 UMOD

8.43e-04255816PS00022
DomainASX_HYDROXYL

CELSR1 CELSR3 CELSR2 UMOD

9.39e-04100814PS00010
DomainEGF-like_CS

CELSR1 STAB2 CELSR3 CELSR2 SLIT3 UMOD

9.51e-04261816IPR013032
Domain-

STAB2 UMOD

9.96e-04118122.40.155.10
DomainGFP-like

STAB2 UMOD

9.96e-0411812IPR023413
DomainR3H

NFX1 NKRF

9.96e-0411812PS51061
DomainFrizzled

FZD10 SMO

9.96e-0411812IPR000539
DomainR3H

NFX1 NKRF

9.96e-0411812PF01424
DomainFrizzled

FZD10 SMO

9.96e-0411812PF01534
Domain-

NFX1 NKRF

9.96e-04118123.30.1370.50
DomainR3H_dom

NFX1 NKRF

9.96e-0411812IPR001374
DomainFrizzled

FZD10 SMO

9.96e-0411812SM01330
DomainEGF_2

CELSR1 STAB2 CELSR3 CELSR2 SLIT3 UMOD

1.03e-03265816PS01186
DomainEGF_3

STAB2 UMOD

1.19e-0312812PF12947
DomainTIL

BMPER MUC5AC

1.19e-0312812PF01826
DomainEGF_dom

STAB2 UMOD

1.19e-0312812IPR024731
DomainC8

BMPER MUC5AC

1.19e-0312812PF08742
DomainG_PROTEIN_RECEP_F2_2

CELSR1 CELSR3 CELSR2

1.33e-0350813PS00650
Domain7tm_2

CELSR1 CELSR3 CELSR2

1.33e-0350813PF00002
DomainUnchr_dom_Cys-rich

BMPER MUC5AC

1.40e-0313812IPR014853
DomainC8

BMPER MUC5AC

1.40e-0313812SM00832
DomainZP_1

ZPLD1 UMOD

1.63e-0314812PS00682
DomainTIL_dom

BMPER MUC5AC

1.63e-0314812IPR002919
DomainZP_2

ZPLD1 UMOD

1.63e-0314812PS51034
DomainZP

ZPLD1 UMOD

1.88e-0315812SM00241
DomainVWD

BMPER MUC5AC

2.14e-0316812SM00216
DomainVWF_type-D

BMPER MUC5AC

2.14e-0316812IPR001846
DomainVWFD

BMPER MUC5AC

2.14e-0316812PS51233
DomainVWD

BMPER MUC5AC

2.14e-0316812PF00094
DomainFrizzled/SFRP

FZD10 SMO

2.14e-0316812IPR015526
DomainZP_dom

ZPLD1 UMOD

2.42e-0317812IPR001507
DomainZona_pellucida

ZPLD1 UMOD

2.42e-0317812PF00100
DomainCTCK_1

SLIT3 MUC5AC

2.72e-0318812PS01185
DomainDSRM

DICER1 NKRF

3.03e-0319812SM00358
Domaindsrm

DICER1 NKRF

3.36e-0320812PF00035
DomainFRI

FZD10 SMO

3.36e-0320812SM00063
Domain-

FZD10 SMO

3.70e-03218121.10.2000.10
DomainCT

SLIT3 MUC5AC

4.06e-0322812SM00041
Pubmed

Human MARCH1, 2, and 8 block Ebola virus envelope glycoprotein cleavage via targeting furin P domain.

MARCHF8 MARCHF2 MARCHF1

1.26e-08382338299743
Pubmed

The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.

CELSR1 CELSR3 CELSR2

1.26e-08382311677057
Pubmed

The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.

CELSR1 CELSR3 CELSR2

5.04e-08482337224017
Pubmed

Intestinal calcium transporter genes are upregulated by estrogens and the reproductive cycle through vitamin D receptor-independent mechanisms.

ESR1 ESR2 TRPV6

5.04e-08482314584880
Pubmed

Developmental expression profiles of Celsr (Flamingo) genes in the mouse.

CELSR1 CELSR3 CELSR2

5.04e-08482311850187
Pubmed

Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues.

CELSR1 CELSR3 CELSR2

4.39e-07782317937400
Pubmed

Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.

CELSR3 CELSR2 SLIT3

1.05e-0698239693030
Pubmed

A dual role for planar cell polarity genes in ciliated cells.

CELSR1 CELSR3 CELSR2

2.06e-061182325024228
Pubmed

Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development.

CELSR1 CELSR3 CELSR2

2.74e-061282311891983
Pubmed

Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice.

CELSR1 CELSR3 CELSR2

2.74e-061282320631168
Pubmed

Mesenchymal Vangl1 and Vangl2 facilitate airway elongation and widening independently of the planar cell polarity complex.

CELSR1 CELSR3 CELSR2

4.51e-061482339225402
Pubmed

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.

CELSR1 CELSR3 CELSR2 FZD10

4.74e-064782433141892
Pubmed

Reduced expression of oestrogen receptor-β is associated with tumour invasion and metastasis in oestrogen receptor-α-negative human papillary thyroid carcinoma.

ESR1 ESR2

5.49e-06282229655286
Pubmed

CpG methylation of the ERalpha and ERbeta genes in breast cancer.

ESR1 ESR2

5.49e-06282215254780
Pubmed

Chronic estradiol treatment reduces platelet responses and protects mice from thromboembolism through the hematopoietic estrogen receptor α.

ESR1 ESR2

5.49e-06282222776819
Pubmed

Neutrophil defensins enhance lung epithelial wound closure and mucin gene expression in vitro.

DEFA1 DEFA3

5.49e-06282212871849
Pubmed

Alleles and haplotypes of the estrogen receptor alpha gene are associated with an increased risk of spontaneous abortion.

ESR1 ESR2

5.49e-06282219200973
Pubmed

Estrogen receptor alpha and beta polymorphisms are associated with semen quality.

ESR1 ESR2

5.49e-06282219959825
Pubmed

Role of estrogen receptor α and β in preserving hippocampal function during aging.

ESR1 ESR2

5.49e-06282223392694
Pubmed

Effects of ERβ and ERα on OVX-induced changes in adiposity and insulin resistance.

ESR1 ESR2

5.49e-06282232053493
Pubmed

Different expression of estrogen receptors alpha and beta in human myometrium and leiomyoma during the proliferative phase of the menstrual cycle and after GnRHa treatment.

ESR1 ESR2

5.49e-06282211826769
Pubmed

Ablation of estrogen receptor alpha or beta eliminates sex differences in mechanical pain threshold in normal and inflamed mice.

ESR1 ESR2

5.49e-06282219285805
Pubmed

Expression of estrogen receptors in the pelvic floor of pre- and post-menopausal women presenting pelvic organ prolapse.

ESR1 ESR2

5.49e-06282222038234
Pubmed

Differential association of juvenile and adult systemic lupus erythematosus with genetic variants of oestrogen receptors alpha and beta.

ESR1 ESR2

5.49e-06282220961965
Pubmed

Polymorphisms in the estrogen receptor beta gene but not estrogen receptor alpha gene affect the risk of developing endometriosis in a Japanese population.

ESR1 ESR2

5.49e-06282215193490
Pubmed

Tamoxifen induces hypercoagulation and alterations in ERα and ERβ dependent on breast cancer sub-phenotype ex vivo.

ESR1 ESR2

5.49e-06282233159119
Pubmed

Phytoestrogens induce differential estrogen receptor alpha- or Beta-mediated responses in transfected breast cancer cells.

ESR1 ESR2

5.49e-06282216118406
Pubmed

Expression of aromatase and estrogen receptors in lumbar motoneurons of mice.

ESR1 ESR2

5.49e-06282228501695
Pubmed

Estradiol-induced proliferation of papillary and follicular thyroid cancer cells is mediated by estrogen receptors alpha and beta.

ESR1 ESR2

5.49e-06282220372779
Pubmed

Human permanent tooth sizes are associated with genes encoding oestrogen receptors.

ESR1 ESR2

5.49e-06282232985343
Pubmed

The distribution of cells containing estrogen receptor-alpha (ERalpha) and ERbeta messenger ribonucleic acid in the preoptic area and hypothalamus of the sheep: comparison of males and females.

ESR1 ESR2

5.49e-06282210919284
Pubmed

Estrogen Receptor Expression in Pancreatic Adenocarcinoma: Time to Reconsider Evidence.

ESR1 ESR2

5.49e-06282234860807
Pubmed

Receptor null mice reveal contrasting roles for estrogen receptor alpha and beta in reproductive tissues.

ESR1 ESR2

5.49e-06282211162937
Pubmed

Estrogen receptor alpha and beta polymorphisms: is there an association with bone mineral density, plasma lipids, and response to postmenopausal hormone therapy?

ESR1 ESR2

5.49e-06282216735942
Pubmed

Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours.

ESR1 ESR2

5.49e-06282216880783
Pubmed

Endogenous estradiol and its association with estrogen receptor gene polymorphisms.

ESR1 ESR2

5.49e-06282216949384
Pubmed

Estrogen receptor genotype and risk of cognitive impairment in elders: findings from the Health ABC study.

ESR1 ESR2

5.49e-06282217889406
Pubmed

Sex steroid hormone polymorphisms, high-density lipoprotein cholesterol, and apolipoprotein A-1 from the Study of Women's Health Across the Nation (SWAN).

ESR1 ESR2

5.49e-06282216949390
Pubmed

The association of bone mineral density with estrogen receptor gene polymorphisms.

ESR1 ESR2

5.49e-06282216949392
Pubmed

Sex differences in exercise-induced physiological myocardial hypertrophy are modulated by oestrogen receptor beta.

ESR1 ESR2

5.49e-06282224654233
Pubmed

Sex-Specific Involvement of Estrogen Receptors in Behavioral Responses to Stress and Psychomotor Activation.

ESR1 ESR2

5.49e-06282230863326
Pubmed

Estrogen receptor α- (ERα), but not ERβ-signaling, is crucially involved in mechanostimulation of bone fracture healing by whole-body vibration.

ESR1 ESR2

5.49e-06282229367057
Pubmed

Immunohistochemical expression of estrogen receptors alpha and beta in lobular neoplasia.

ESR1 ESR2

5.49e-06282217924141
Pubmed

Differential expression of estrogen receptor α and β isoforms in multiple and solitary leiomyomas.

ESR1 ESR2

5.49e-06282226529545
Pubmed

Roles of estrogen receptor α and β in the regulation of proliferation in endometrial carcinoma.

ESR1 ESR2

5.49e-06282232853964
Pubmed

Localization of estrogen and androgen receptors in male reproductive tissues of mice and rats.

ESR1 ESR2

5.49e-06282215278948
Pubmed

Pregnancy and oestrogen regulate sinoatrial node calcium homeostasis and accelerate pacemaking.

ESR1 ESR2

5.49e-06282229800268
Pubmed

The differential fate of mesonephric tubular-derived efferent ductules in estrogen receptor-alpha knockout versus wild-type female mice.

ESR1 ESR2

5.49e-06282211014235
Pubmed

17Beta-estradiol regulation of the mRNA expression of T-type calcium channel subunits: role of estrogen receptor alpha and estrogen receptor beta.

ESR1 ESR2

5.49e-06282219003958
Pubmed

Differential expression patterns and clinical significance of estrogen receptor-α and β in papillary thyroid carcinoma.

ESR1 ESR2

5.49e-06282224884830
Pubmed

Phytoestrogen-mediated inhibition of proliferation of the human T47D breast cancer cells depends on the ERalpha/ERbeta ratio.

ESR1 ESR2

5.49e-06282218955141
Pubmed

Estrogen receptor-beta mediates male-female differences in the development of pressure overload hypertrophy.

ESR1 ESR2

5.49e-06282215374829
Pubmed

Bioassays for estrogenic activity: development and validation of estrogen receptor (ERalpha/ERbeta) and breast cancer proliferation bioassays to measure serum estrogenic activity in clinical studies.

ESR1 ESR2

5.49e-06282219382890
Pubmed

Variants in estrogen receptor alpha gene are associated with phenotypical expression of obsessive-compulsive disorder.

ESR1 ESR2

5.49e-06282220850223
Pubmed

The influence of ESR1 rs9340799 and ESR2 rs1256049 polymorphisms on prostate cancer risk.

ESR1 ESR2

5.49e-06282224859835
Pubmed

Support of a bi-faceted role of estrogen receptor β (ERβ) in ERα-positive breast cancer cells.

ESR1 ESR2

5.49e-06282224192230
Pubmed

Effects of estrogen on the vascular injury response in estrogen receptor alpha, beta (double) knockout mice.

ESR1 ESR2

5.49e-06282211557741
Pubmed

Transgenic models of metabolic bone disease: impact of estrogen receptor deficiency on skeletal metabolism.

ESR1 ESR2

5.49e-06282212952206
Pubmed

Determination of the isoflavone composition and estrogenic activity of commercial dietary supplements based on soy or red clover.

ESR1 ESR2

5.49e-06282226023053
Pubmed

Both estrogen receptor-alpha and -beta are required for sexual differentiation of the anteroventral periventricular area in mice.

ESR1 ESR2

5.49e-06282216239299
Pubmed

Estrogen receptor beta-deficient female mice develop a bladder phenotype resembling human interstitial cystitis.

ESR1 ESR2

5.49e-06282217522255
Pubmed

Ratio of Circulating Estrogen Receptors Beta and Alpha (ERβ/ERα) Indicates Endoscopic Activity in Patients with Crohn's Disease.

ESR1 ESR2

5.49e-06282228823012
Pubmed

Estrogen receptor polymorphisms and the vascular effects of hormone therapy.

ESR1 ESR2

5.49e-06282221106950
Pubmed

Untangling the human estrogen receptor gene structure.

ESR1 ESR2

5.49e-06282212111450
Pubmed

Generation and reproductive phenotypes of mice lacking estrogen receptor beta.

ESR1 ESR2

5.49e-0628229861029
Pubmed

Molecular analysis of the estrogen receptor alpha gene in men with coronary artery disease: association with disease status.

ESR1 ESR2

5.49e-06282212691862
Pubmed

Human Neutrophil Peptides 1-3--early markers in development of colorectal adenomas and carcinomas.

DEFA1 DEFA3

5.49e-06282218957723
Pubmed

Association of promoter methylation of ERα and ERβ with sporadic breast cancer--a study from North India.

ESR1 ESR2

5.49e-06282224833090
Pubmed

Long-Term Neonatal Estrogen Exposure Causes Irreversible Inhibition of LH Pulses by Suppressing Arcuate Kisspeptin Expression via Estrogen Receptors α and β in Female Rodents.

ESR1 ESR2

5.49e-06282228368450
Pubmed

Estrogen receptor beta mediates gender differences in ischemia/reperfusion injury.

ESR1 ESR2

5.49e-06282215698835
Pubmed

The oxidative stress in breast tumors of postmenopausal women is ERα/ERβ ratio dependent.

ESR1 ESR2

5.49e-06282223499841
Pubmed

The ERalpha/ERbeta ratio determines oxidative stress in breast cancer cell lines in response to 17beta-estradiol.

ESR1 ESR2

5.49e-06282222615145
Pubmed

Novel effects of estradiol and estrogen receptor alpha and beta on cognitive function.

ESR1 ESR2

5.49e-06282211074057
Pubmed

Estrogen receptors and gonadal steroids in vulnerability and protection of dopamine neurons in a mouse model of Parkinson's disease.

ESR1 ESR2

5.49e-06282221586296
Pubmed

Effects of low-magnitude high-frequency vibration on osteoblasts are dependent on estrogen receptor α signaling and cytoskeletal remodeling.

ESR1 ESR2

5.49e-06282230093109
Pubmed

Estrogen receptors in breast carcinogenesis and endocrine therapy.

ESR1 ESR2

5.49e-06282225433206
Pubmed

Estrogen receptor null mice: what have we learned and where will they lead us?

ESR1 ESR2

5.49e-06282210368776
Pubmed

Association of estrogen receptor gene polymorphisms with susceptibility to adolescent idiopathic scoliosis.

ESR1 ESR2

5.49e-06282216648749
Pubmed

Differential regulation of proteasome-dependent estrogen receptor alpha and beta turnover in cultured human uterine artery endothelial cells.

ESR1 ESR2

5.49e-06282212727987
Pubmed

Evidence for functional estrogen receptors alpha and beta in human adipose cells: regional specificities and regulation by estrogens.

ESR1 ESR2

5.49e-06282214761887
Pubmed

Expression of estrogen receptor alpha and beta in breast cancers of pre- and post-menopausal women.

ESR1 ESR2

5.49e-06282218752050
Pubmed

Estrogen receptors alpha and beta in choroid plexus epithelial cells in Alzheimer's disease.

ESR1 ESR2

5.49e-06282215082146
Pubmed

Significance of immunohistochemical expression of estrogen receptors alpha and beta in squamous cell carcinoma of the esophagus.

ESR1 ESR2

5.49e-06282217634528
Pubmed

Gonadotropin-positive pituitary tumors accompanied by ovarian tumors in aging female ERbeta-/- mice.

ESR1 ESR2

5.49e-06282220308571
Pubmed

Association of polymorphisms in the estrogen receptors alpha, and beta (ESR1, ESR2) with the occurrence of male infertility and semen parameters.

ESR1 ESR2

5.49e-06282220599614
Pubmed

Sex-dependent association of blood pressure with oestrogen receptor genes ERalpha and ERbeta.

ESR1 ESR2

5.49e-06282215167447
Pubmed

Signal cross-talk between estrogen receptor alpha and beta and the peroxisome proliferator-activated receptor gamma1 in MDA-MB-231 and MCF-7 breast cancer cells.

ESR1 ESR2

5.49e-06282212242035
Pubmed

Peritoneal fluid macrophages in endometriosis: correlation between the expression of estrogen receptors and inflammation.

ESR1 ESR2

5.49e-06282217548071
Pubmed

[Prognostic value of estrogen receptors--ERalpha and ERbeta, in patients with lung cancer].

ESR1 ESR2

5.49e-06282221972702
Pubmed

The role of allelic variation in estrogen receptor genes and major depression in the Nurses Health Study.

ESR1 ESR2

5.49e-06282226169989
Pubmed

A novel shift in estrogen receptor expression occurs as estradiol suppresses inflammation-associated colon tumor formation.

ESR1 ESR2

5.49e-06282223702470
Pubmed

Impaired estrogen signaling underlies regulatory T cell loss-of-function in the chronically inflamed intestine.

ESR1 ESR2

5.49e-06282232632016
Pubmed

Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.

ESR1 ESR2

5.49e-06282216648639
Pubmed

Association between polymorphisms in genes encoding estrogen receptors (ESR1 and ESR2) and excreted bisphenol A levels after orthodontic bracket bonding: a preliminary study.

ESR1 ESR2

5.49e-06282229961922
Pubmed

Smoothened stabilizes and protects TRAF6 from degradation: A novel non-canonical role of smoothened with implications in lymphoma biology.

TRAF6 SMO

5.49e-06282230165192
Pubmed

Associations between estrogen receptor genetic polymorphisms, smoking status, and prostate cancer risk: a case-control study in Japanese men.

ESR1 ESR2

5.49e-06282226251204
Pubmed

Bisphenol A exposure in utero disrupts early oogenesis in the mouse.

ESR1 ESR2

5.49e-06282217222059
Pubmed

Site-specific regulation of oestrogen receptor-alpha and -beta by oestradiol in human adipose tissue.

ESR1 ESR2

5.49e-06282211703424
Pubmed

Estrogen receptor beta gene variant is associated with vascular dementia in elderly women.

ESR1 ESR2

5.49e-06282219473078
Pubmed

3D models of human ERα and ERβ complexed with 5-androsten-3β,17β-diol.

ESR1 ESR2

5.49e-06282222921477
CytobandEnsembl 112 genes in cytogenetic band chr4q32

TRIM75 FSTL5 MARCHF1

1.33e-03120823chr4q32
Cytoband4q32.3

TRIM75 FSTL5

1.70e-03348224q32.3
Cytoband1p33

CYP4Z1 CYP4X1

1.80e-03358221p33
GeneFamilyAdhesion G protein-coupled receptors, subfamily C|CELSR cadherins

CELSR1 CELSR3 CELSR2

4.65e-083663913
GeneFamilyAdhesion G protein-coupled receptors, subfamily C|CELSR cadherins

CELSR1 CELSR3 CELSR2

4.65e-0836631189
GeneFamilyRing finger proteins

CBLL1 TRAF6 TRIM75 MARCHF8 MARCHF2 SCAF11 TRIM77 TRIM27 MARCHF1

6.63e-0727566958
GeneFamilyRing finger proteins|Membrane associated ring-CH-type fingers

MARCHF8 MARCHF2 MARCHF1

7.51e-061166360
GeneFamilyAnoctamins

ANO4 ANO3

5.80e-0410662865
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD10 SMO

7.07e-0411662286
GeneFamilyDefensins, alpha

DEFA1 DEFA3

8.46e-0412662502
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM75 TRIM77 TRIM27

5.06e-039566359
GeneFamilyCytochrome P450 family 4

CYP4Z1 CYP4X1

7.63e-03366621003
ToppCellBronchus_Control_(B.)-Stromal-TX-Mesothelial-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

LPAR4 SLIT3 MMP23B SMO BMPER PRG4

1.84e-0619982660a653100aff31f7f96796ff2ec634798bfb4b0d
ToppCellKidney-Keratinocytes|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.

IL34 ADORA2B CNFN SCEL RFX8 USP9Y

1.89e-0620082641d83faa9f45ee7ea2ab19be8ecc6d2c5ac7fe5d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

USP44 CELSR1 GPC5 MARVELD3 SCEL

8.01e-061488259fe3c0a5904b8e9a0f28130f8d84d4f2a819b06c
ToppCellfacs-Marrow-KLS-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP23B FZD10 BMPER RFX8 NKRF

1.28e-05163825b83a35c4426d66b5734a98fa6c72b345fe462030
ToppCellfacs-Marrow-KLS-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP23B FZD10 BMPER RFX8 NKRF

1.28e-05163825c20ca9b6b4170ebcb0e66eef3e5d8ebff22b1a91
ToppCellfacs-Marrow-KLS-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP23B FZD10 BMPER RFX8 NKRF

1.32e-05164825d2b5f51af7fcffddebe997ee302bacbd85d76852
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP4Z1 ESR1 CYP4X1 ANO3 KCNT1

1.48e-051688254b2d29a7843bf45922038c093ca7ec0600756adc
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 ADORA2B SLIT3 MARCHF1 WDPCP

1.52e-0516982515a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANO4 TRAF6 ASIC1 FSTL5 MARCHF1

1.57e-0517082514aa86a4f526ed6986afcb28c49225522055550c
ToppCellASK440-Epithelial-Transformed_epithelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

CELSR2 CYP4Z1 SLIT3 PRG4 ANO3

1.66e-05172825df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|356C / Donor, Lineage, Cell class and subclass (all cells)

CYP4X1 TRPV6 SMO MUC5AC FAM221B

1.80e-05175825af9c5104c86231cfdb93a0f7d7032379efaa009e
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|356C / Donor, Lineage, Cell class and subclass (all cells)

CYP4X1 TRPV6 SMO MUC5AC FAM221B

1.80e-051758254bfae78ac3a2cb9404382aae96d291504a9cfa14
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CELSR1 CYP4Z1 CYP4X1 GPC5 SCEL

2.29e-0518482529c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA2B TIMP2 SLIT3 MMP23B PRG4

2.41e-05186825ff6ccfdf2509f96caa10281c29a95b432f6c6dcc
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

CELSR1 CYP4Z1 CYP4X1 GPC5 SCEL

2.41e-0518682509d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CELSR1 CYP4Z1 CYP4X1 GPC5 SCEL

2.54e-05188825eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CELSR1 FSTL5 GPC5 MARVELD3 MUC5AC

2.74e-0519182505731ece7867659c662f952812805f947032fe10
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA2B ASIC1 FSTL5 GPC5 SCEL

2.74e-05191825ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA2B ASIC1 FSTL5 GPC5 SCEL

2.74e-05191825478e8341ee03b05501e2233e02cef5f97492c95d
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

USP44 MARCHF8 INTS9 USP9Y DICER1

2.74e-05191825cadb7a9de16f4bb21606de0e25cddd2d748c7f0b
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP2 SLIT3 MMP23B BMPER PRG4

2.81e-05192825853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP2 SLIT3 MMP23B BMPER PRG4

2.81e-05192825d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP2 SLIT3 MMP23B BMPER PRG4

2.81e-0519282549281626ecad0456fdbded2378b7028d7b589686
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CELSR1 FSTL5 GPC5 MARVELD3 MUC5AC

2.88e-05193825aa10924b203c71e65fdbd2b90ba131dbd362d8b1
ToppCellVE-mDC1-|VE / Condition, Cell_class and T cell subcluster

ZNF462 ADORA2B CNFN SMO MARCHF1

2.88e-051938255df6033bc0e4f96a20d526486a8e89c990e21831
ToppCellVE-mDC1|VE / Condition, Cell_class and T cell subcluster

ZNF462 ADORA2B CNFN SMO MARCHF1

2.88e-0519382512b2708db9db8b88365b8ebeb4908f28c50081bb
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-airway_progenitor_early|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CELSR1 FSTL5 GPC5 MARVELD3 MUC5AC

2.88e-05193825de569c6e507856fd3ac2311f246cb597074ed30c
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-airway_progenitor_early|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CELSR1 SINHCAF FSTL5 GPC5 MARVELD3

3.18e-051978254ae08ccb6f1da626c4f0fb0140a2811cb6e31ba1
ToppCellParenchymal-10x3prime_v2-Stromal-Mesofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ESR1 SLIT3 MMP23B RFX8 PRG4

3.25e-051988250cd930e374c2c48d1991b51c025f9801b22ecee7
ToppCellParenchymal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ESR1 SLIT3 MMP23B RFX8 PRG4

3.25e-05198825e0df6d6ff2a9c41d813f84a2a5ee7cb5f6fc3e30
ToppCellCOVID_non-vent-Myeloid-Monocytic-Developing_Neutrophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

DEFA1 DEFA3 OR2W3 CNFN

1.01e-041318245b29f0dc449b9fff5e8bf6365080168f31b7e268
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D231|Adult / Lineage, Cell type, age group and donor

IL34 CELSR3 GPC5 SCEL

1.04e-041328248d30b71776f5f6da55dc78e0c5cb27be460004e3
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp4_Mab21l1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DEFA3 TRAF6 FSTL5 BMPER

1.16e-041368249cf076597e6fd9390850fda259daa13022f15893
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_2|E16.5-samps / Age Group, Lineage, Cell class and subclass

ASIC1 TTC16 ESR1 BMPER

1.23e-0413882405de2cef97c0912fb23f138dd45348f565a14d74
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANO4 ASIC1 FSTL5 MARVELD3

1.65e-0414982410ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CELSR3 SACS SLC25A29 MARCHF1

1.70e-0415082453de595376a9fc92491dfd58ff25938b0bf79903
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CELSR3 SACS SLC25A29 MARCHF1

1.70e-04150824e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Club|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

SPACA4 ESR2 CYP4X1 MUC5AC

2.07e-0415882403281e87780e3bacd089903383c016d03c373bf7
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 STAB2 DOCK9 FNDC8

2.22e-04161824133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 STAB2 DOCK9 FNDC8

2.22e-041618249466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 STAB2 DOCK9 FNDC8

2.22e-04161824cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IL34 ESR1 SLIT3 ANO3

2.28e-0416282468c40d12689cc1b6c797e6e48173f0110f8144e4
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 STAB2 DOCK9 FNDC8

2.28e-0416282496c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IL34 ESR1 SLIT3 ANO3

2.28e-04162824735fa3f77b31a4189e431d05c326403c18cbbffb
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ESR2 DEF6 MMP23B FAM221B

2.44e-041658248b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCell368C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

THAP3 SCEL ZNF598 PRG4

2.44e-041658249d2bdc42c13c8c2a68889bec8612a1ce56f659fa
ToppCellcontrol-Myeloid-pDC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ESR2 DEF6 MMP23B FAM221B

2.44e-04165824243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLIT3 MUC5AC KCNT1 MOCS1

2.44e-041658248a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA2B TRPV6 IL18RAP MOCS1

2.50e-04166824c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA2B TRPV6 IL18RAP MOCS1

2.50e-041668240975fc165bcc7e85f053d9d0244fffe407c23571
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

SMO BMPER ANO3 SEMA4C

2.56e-04167824d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMS22L ESR1 DEF6 IL18RAP

2.61e-0416882493b7138f17aa14a6398c9b4ea7237781a0e19a66
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL34 ESR1 SLIT3 PRG4

2.61e-04168824d19a115365c5415e51c039718d7669de788fcf33
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMS22L ESR1 DEF6 IL18RAP

2.61e-04168824e393553208617a023f1646169c892a87c95db3f5
ToppCelldroplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP2 RFX8 MUC5AC SEMA4C

2.67e-041698247962165cab84af73d20b56eb70b1ed87c94025ef
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP4Z1 ESR1 CYP4X1 KCNT1

2.80e-041718245d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Sncg_(Neuron.Gad1Gad2.Synpr-Sncg)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ZPLD1 ESR2 FNDC8

2.80e-04698239778ec48eceef5bd6f59b5b55ca4a6cc348a1eba
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Sncg_(Neuron.Gad1Gad2.Synpr-Sncg)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ZPLD1 ESR2 FNDC8

2.80e-04698238c4c4e2cd4c319adbe44fa2bcb5bb5cd5d81a2fd
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

TRPV6 SLC25A29 SCEL MUC5AC

2.86e-041728240be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

SLIT3 CCNP BMPER MOCS1

2.92e-04173824fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 DEF6 IL18RAP PRG4

2.99e-041748241c073177c1753e3b91ef8fd9e95230a1d13c82f3
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

IL34 CELSR2 CCNP SLC25A29

2.99e-041748249e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 DEF6 IL18RAP PRG4

2.99e-041748245491ad5c144baf2ef9b1c58eb720c872d14feb15
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SINHCAF MMP23B SLC25A29 BMPER

3.05e-041758241b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 ADORA2B MARCHF8 IL18RAP

3.05e-041758241b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADORA2B MMS22L SACS SLC25A29

3.05e-04175824a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADORA2B MMS22L SACS SLC25A29

3.05e-041758248b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 ADORA2B MARCHF8 IL18RAP

3.05e-04175824a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCellfacs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 STAB2 FNDC8 KCNT1

3.12e-04176824057d2759fdc67176c25802b57a78064d8cc93205
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 STAB2 FNDC8 KCNT1

3.12e-04176824b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CELSR1 ESR2 SLIT3 MARCHF1

3.19e-04177824da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5|TCGA-Skin / Sample_Type by Project: Shred V9

LPAR4 BMPER RFX8 ANO3

3.26e-04178824ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT3 MMP23B SCEL KCNT1

3.26e-041788246d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT3 MMP23B SCEL KCNT1

3.26e-04178824d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCellASK440-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CYP4Z1 SLIT3 PRG4 ANO3

3.26e-0417882486f1741636ed3e85bb4a65f84949b718fc38c290
ToppCelldroplet-Bladder-nan-24m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SACS SLIT3 RFX8 IL18RAP

3.33e-04179824dfd9d29281510d32f1a2e8336d2e58ef496cfd1d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP44 CELSR2 GPC5 SCEL

3.33e-04179824cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CELSR1 PLA2G12B UMOD GPC5

3.33e-04179824815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD10 SMO BMPER MOCS1

3.33e-04179824a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Alox5+_Lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 STAB2 FZD10 PRG4

3.40e-04180824b28363626f4d2a552abde3434cc1df2e2121aba5
ToppCelldroplet-Limb_Muscle-nan-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP2 SLIT3 BMPER PRG4

3.40e-04180824d3d0be136fff5d3e39ecf5a5dbefc1d0d0a6c814
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 STAB2 FZD10 PRG4

3.40e-0418082467b062f2ef7e20f392e00c646f4985c415d40de9
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CELSR1 SLIT3 MARCHF1 ANO3

3.40e-04180824e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6_(Thalamus,_glutamatergic)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

RFX8 USP9Y IL18RAP

3.45e-0474823ef4c9eafc794c7d50aef28b37d21b52d3c511499
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6_(Thalamus,_glutamatergic)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

RFX8 USP9Y IL18RAP

3.45e-04748236ecbdf4186039a031410e09ecd5afa66b6d5e2dc
ToppCellfacs-Kidney-nan-24m-Mesenchymal-kidney_interstitial_fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA2B MMS22L TIMP2 MMP23B

3.47e-04181824c7f5aedcb74c21fb587a95a16d700e2a38a380ee
ToppCellfacs-Kidney-nan-24m-Mesenchymal-kidney_interstitial_fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA2B MMS22L TIMP2 MMP23B

3.47e-041818240ec9621a078d004bbd25a587757d24b5cf162959
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELSR1 STAB2 FNDC8 KCNT1

3.54e-041828242cc434e46985c66fc36de05344a67aa96d90abc9
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO4 TIMP2 ASIC1 FSTL5

3.54e-04182824420a8fd30543e37a66ba0786215d056d308660d0
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELSR1 STAB2 FNDC8 KCNT1

3.54e-041828240cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF142 NFX1 MUC5AC MOCS1

3.54e-04182824818b5155ec81f0059048d6070a108116ecd72e3c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CELSR1 FSTL5 SLIT3 ANO3

3.54e-0418282472e65a23cd36085bc880087d3cae92395de918a1
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELSR1 STAB2 FNDC8 KCNT1

3.54e-041828243e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CELSR1 FSTL5 SLIT3 ANO3

3.54e-0418282405c167158815bf25d509df59ab386e1990712765
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CELSR1 FSTL5 GPC5 MARVELD3

3.62e-04183824c5b10571599dc26476170b54b53f09c23e6b3117
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Late_airway_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CELSR2 TRPV6 GPC5 MARVELD3

3.62e-041838240cea883a8a79fc58abcb26b08bf5db9d3d60f7d4
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

UMOD BMPER RFX8 MOCS1

3.62e-04183824fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL34 ESR1 SLIT3 ANO3

3.69e-04184824c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL34 ESR1 SLIT3 ANO3

3.69e-04184824e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

CYP4Z1 CYP4X1 GPC5 SCEL

3.69e-04184824561592edc3083fad41b91811151b442207c65dd9
Drug4-fluorobenzoyl chloride

DEFA1 DEFA3 ESR1

1.80e-074823CID000067879
DrugP 14

DEFA1 DEFA3 ESR2

1.25e-0513823CID000056603
Drug5-octylphenol

ESR1 ESR2

1.28e-052822ctd:C113977
Drug2-methoxyethoxy)acetic acid

DEFA1 DEFA3

1.28e-052822CID000027642
Drugtetradifon

ESR1 ESR2

1.28e-052822ctd:C005807
Drugetocrylene

ESR1 ESR2

1.28e-052822CID000243274
DrugRaloxifene

ESR1 ESR2

1.28e-052822DB00481
DrugBrn 0187733

ESR1 ESR2

1.28e-052822CID000160446
DrugPHTPP

ESR1 ESR2

1.28e-052822CID011201035
Drugbutolame

ESR1 ESR2

1.28e-052822CID000197608
DrugLY 326315

ESR1 ESR2

1.28e-052822CID009803972
DrugJK 1624F2-1

ESR1 ESR2

1.28e-052822ctd:C113642
Drugoctocrylene

ESR1 ESR2

1.28e-052822ctd:C088673
DrugO-desmethylangolensin

ESR1 ESR2

1.28e-052822ctd:C050052
DrugCHEMBL397775

ESR1 ESR2

1.28e-052822CID010214678
DrugCyclohexanone, 3b

ESR1 ESR2

1.28e-052822CID011370317
DrugCHEMBL234633

ESR1 ESR2

1.28e-052822CID010192968
DrugSureCN14514707

ESR1 ESR2

1.28e-052822CID010192967
Drug(4R)-6-(ethoxymethyl)-4-(4-hydroxyphenyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol

ESR1 ESR2

1.28e-052822CID011175195
Drug(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL

ESR1 ESR2

1.28e-052822DB08020
Drugethyl cinnamate

ESR1 ESR2

1.28e-052822ctd:C451418
Drug(4R)-4-(4-hydroxyphenyl)-6-methylol-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol

ESR1 ESR2

1.28e-052822CID011174414
Drug1,2,5,6-tetramethylnaphthalene

DEFA1 DEFA3

1.28e-052822CID006427081
Drugphytoene

ESR1 ESR2

1.28e-052822ctd:C100185
DrugCHEMBL48352

ESR1 ESR2

1.28e-052822CID011522286
Drugbromophos

ESR1 ESR2

1.28e-052822ctd:C100092
DrugSureCN14514705

ESR1 ESR2

1.28e-052822CID010125414
Drug3,4-dihydroxybenzaldoxime

ESR1 ESR2

1.28e-052822ctd:C053286
DrugTamoxifen

ESR1 ESR2

1.28e-052822DB00675
DrugSureCN14514737

ESR1 ESR2

1.28e-052822CID010149292
Drugdi-(5-methylhexyl)phthalate

ESR1 ESR2

1.28e-052822ctd:C042791
Drug1,4,5-trimethylnaphthalene

DEFA1 DEFA3

1.28e-052822CID000016478
Drugphytofluene

ESR1 ESR2

1.28e-052822ctd:C003140
Drug1x7e

ESR1 ESR2

1.28e-052822CID000656953
Drugsalicylaldoxime

ESR1 ESR2

1.28e-052822ctd:C005704
DrugPyrazolo[1,5-a]pyrimidine, 12d

ESR1 ESR2

1.28e-052822CID016103245
DrugPyrazolo[1,5-a]pyrimidine, 12c

ESR1 ESR2

1.28e-052822CID016103238
DrugSureCN3587271

ESR1 ESR2

1.28e-052822CID011208678
DrugCNP-amino

ESR1 ESR2

1.28e-052822CID000033473
DrugERB 041

ESR1 ESR2

1.28e-052822ctd:C478102
Drug(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL

ESR1 ESR2

1.28e-052822DB07933
Drug4-(4-hydroxyphenyl)-6-methyl-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol

ESR1 ESR2

1.28e-052822CID010125512
Drug2-phenylbenzofuran

ESR1 ESR2

1.28e-052822CID003517936
Drugsteroid C

ESR1 ESR2

1.28e-052822CID000454473
Drugp-sulfobenzyl alcohol

DEFA1 DEFA3

1.28e-052822CID000441138
Drug2z4b

ESR1 ESR2

1.28e-052822CID011197931
Drugdehydroestrone

ESR1 ESR2

1.28e-052822CID000102225
Drug(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL

ESR1 ESR2

1.28e-052822DB07638
Drugprolame

ESR1 ESR2

1.28e-052822CID000127441
Drugbenzohydrol

ESR1 ESR2

1.28e-052822ctd:C020225
Drugparthenocissin A

ESR1 ESR2

1.28e-052822ctd:C549189
DrugCHEBI:428946

ESR1 ESR2

1.28e-052822CID011688293
DrugF ppt

ESR1 ESR2

1.28e-052822CID003035869
DrugSureCN3118249

ESR1 ESR2

1.28e-052822CID011519653
DrugSureCN4017709

ESR1 ESR2

1.28e-052822CID011256602
DrugCHEBI:428959

ESR1 ESR2

1.28e-052822CID011638242
DrugDNC005795

ESR1 ESR2

1.28e-052822CID011638264
Drugtetrahydrodaidzein

ESR1 ESR2

1.28e-052822ctd:C433164
Drugtri-(2-ethylhexyl)trimellitate

ESR1 ESR2

1.28e-052822ctd:C036101
Drug2-chloro-4-phenylphenol

ESR1 ESR2

1.28e-052822ctd:C012257
Drug2,2,4-trimethyl-1,3-pentanediol diisobutyrate

ESR1 ESR2

1.28e-052822ctd:C001508
Drug2-(3-chloro-4-hydroxyphenyl)-2-(4-hydroxyphenyl)propane

ESR1 ESR2

1.28e-052822ctd:C497826
Drug2,2-bis(3-chloro-4-hydroxyphenyl)propane

ESR1 ESR2

1.28e-052822ctd:C497827
Drug1-ethyl-2-(4-hydroxyphenyl)-3H-inden-5-ol

ESR1 ESR2

1.28e-052822CID011615788
DrugSureCN3593776

ESR1 ESR2

1.28e-052822CID009948127
DrugSureCN14047367

ESR1 ESR2

1.28e-052822CID010171723
DrugY134 compound

ESR1 ESR2

1.28e-052822ctd:C518540
DrugTS 108

ESR1 ESR2

1.28e-052822ctd:C482068
DrugEstriol

ESR1 ESR2

1.28e-052822DB04573
DrugEstropipate

ESR1 ESR2

1.28e-052822DB04574
DrugCHEBI:428952

ESR1 ESR2

1.28e-052822CID011674420
Drug6-(4-hydroxyphenyl)-6,6a,7,8,9,10,11,11a-octahydrocyclohepta[c]chromen-2-ol

ESR1 ESR2

1.28e-052822CID010215026
Drug4-(2-chloro-4-(2-piperidin-1-ylethoxy)phenyl)-5-(2,6-dichloro-4-hydroxyphenyl)-2-imidazoline

ESR1 ESR2

1.28e-052822ctd:C496952
Drugindenestrol

ESR1 ESR2

1.28e-052822ctd:C047437
Drug[5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE

ESR1 ESR2

1.28e-052822DB06927
DrugLY2066948

ESR1 ESR2

1.28e-052822CID005327043
DrugSERBA-2

ESR1 ESR2

1.28e-052822CID009925763
DrugSureCN1360427

ESR1 ESR2

1.28e-052822CID011720174
Drug16 alpha-iodoestradiol

ESR1 ESR2

1.28e-052822ctd:C024871
Drug2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid

ESR1 ESR2

3.84e-053822ctd:C101851
DrugCHF 4056

ESR1 ESR2

3.84e-053822ctd:C450419
DrugDiethylstilbestrol

ESR1 ESR2

3.84e-053822DB00255
DrugAC1LGHHD

ESR1 ESR2

3.84e-053822CID000821427
Drugcyanophenphos

ESR1 ESR2

3.84e-053822ctd:C002488
Drug4-ethylbenzoate

DEFA1 DEFA3

3.84e-053822CID000012086
Drug2,4,6-trichlorophenyl-4'-aminophenyl ether

ESR1 ESR2

3.84e-053822ctd:C067259
Drug7alpha-methyl-17alpha-ethynylestradiol

ESR1 ESR2

3.84e-053822ctd:C475050
Drugbromophos-ethyl

ESR1 ESR2

3.84e-053822CID000020965
Drugdihydrobiochanin A

ESR1 ESR2

3.84e-053822CID000439784
DrugEstradiol

ESR1 ESR2

3.84e-053822DB00783
Drugbicyclo(3.3.1)nonane

ESR1 ESR2

3.84e-053822CID000136101
Drugcedrol

ESR1 ESR2

3.84e-053822ctd:C078669
Drugbenzophenone-6

ESR1 ESR2

3.84e-053822CID000008570
Drugdichlofenthion

ESR1 ESR2

3.84e-053822CID000007328
DrugNafoxidine

ESR1 ESR2

3.84e-053822ctd:D009256
DrugLY2066948

ESR1 ESR2

3.84e-053822ctd:C504960
Drugp-tert-amylphenol

ESR1 ESR2

3.84e-053822ctd:C019566
Drug1-(4-nitro-2-(trifluoromethyl)phenyl)-4-(3-(trifluoromethyl)phenyl)piperazine

ESR1 ESR2

3.84e-053822ctd:C562246
DrugChromans

ESR1 ESR2

3.84e-053822ctd:D002839
Drug4-hydroxybenzophenone

ESR1 ESR2

3.84e-053822ctd:C024292
Diseaseprostate carcinoma in situ (implicated_via_orthology)

ESR1 ESR2

6.55e-062762DOID:8634 (implicated_via_orthology)
Diseaseperitonitis (implicated_via_orthology)

ESR1 ESR2

1.96e-053762DOID:8283 (implicated_via_orthology)
DiseaseSubfertility, Female

ESR1 ESR2 SMO

5.14e-0528763C0341869
DiseaseSterility, Postpartum

ESR1 ESR2 SMO

5.14e-0528763C0038279
DiseaseFemale sterility

ESR1 ESR2 SMO

5.14e-0528763C0917730
DiseaseFemale infertility

ESR1 ESR2 SMO

5.14e-0528763C0021361
Diseaseanxiety measurement

MMS22L ESR1 TRPV6 WDPCP

1.78e-04108764EFO_0009863
Diseaserepulsive guidance molecule A measurement

CELSR2 FAM221B

2.33e-049762EFO_0008273
Diseaseinterleukin 12 measurement

ZNF462 SACS NFX1

3.51e-0453763EFO_0004753
DiseaseProstatic Intraepithelial Neoplasias

ESR1 ESR2

3.55e-0411762C0282612
DiseaseOligospermia

ESR1 DICER1

4.25e-0412762C0028960
Diseasesexual dimorphism measurement

ZNF462 ZNF142 ASIC1 ESR1 ESR2 MARCHF2 SLIT3 DEF6 TRIM27 SDHB

5.32e-0411067610EFO_0021796
DiseaseCoronary Arteriosclerosis

TRAF6 ESR1 ESR2

6.39e-0465763C0010054
DiseaseCoronary Artery Disease

TRAF6 ESR1 ESR2

6.39e-0465763C1956346
DiseaseCorneal astigmatism

DOCK9 BMPER NPLOC4

1.05e-0377763EFO_1002040
Diseaseskin hydration measurement

IL34 FZD10

1.33e-0321762EFO_0009586
Diseasein situ carcinoma (is_marker_for)

ESR1 ESR2

1.33e-0321762DOID:8719 (is_marker_for)
Diseaseosteoporosis (biomarker_via_orthology)

ESR1 ESR2

1.46e-0322762DOID:11476 (biomarker_via_orthology)
Diseasechildhood aggressive behaviour measurement

ZPLD1 RFX8 TRIM27

1.59e-0389763EFO_0007663
Diseasesphingomyelin 24:1 measurement

MMS22L CELSR1

1.60e-0323762EFO_0010398
DiseaseCerebral Astrocytoma

ESR1 ESR2

1.89e-0325762C0750935
DiseaseIntracranial Astrocytoma

ESR1 ESR2

1.89e-0325762C0750936
DiseasePilocytic Astrocytoma

ESR1 ESR2

1.89e-0325762C0334583
DiseaseAstrocytoma

ESR1 ESR2

1.89e-0325762C0004114
DiseaseJuvenile Pilocytic Astrocytoma

ESR1 ESR2

1.89e-0325762C0280783
DiseaseDiffuse Astrocytoma

ESR1 ESR2

1.89e-0325762C0280785
DiseaseGrade I Astrocytoma

ESR1 ESR2

1.89e-0325762C1704230
DiseaseSubependymal Giant Cell Astrocytoma

ESR1 ESR2

1.89e-0325762C0205768
DiseaseMixed oligoastrocytoma

ESR1 ESR2

1.89e-0325762C0547065
DiseaseChildhood Cerebral Astrocytoma

ESR1 ESR2

1.89e-0325762C0338070
DiseaseGemistocytic astrocytoma

ESR1 ESR2

2.04e-0326762C0334581
DiseaseProtoplasmic astrocytoma

ESR1 ESR2

2.04e-0326762C0334580
DiseaseFibrillary Astrocytoma

ESR1 ESR2

2.04e-0326762C0334582
DiseaseAnaplastic astrocytoma

ESR1 ESR2

2.20e-0327762C0334579
Diseaseosteoarthritis (is_implicated_in)

ESR1 ESR2

2.37e-0328762DOID:8398 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
CCLVKCLFENVVPMS

ADORA2B

166

P29275
ICLREPCENYMKCVS

CELSR1

1306

Q9NYQ6
ICLREPCENYMRCVS

CELSR2

1231

Q9HCU4
ATDIIMCPVCDKYCP

ANO4

391

Q32M45
ACLFVACKMEECVLP

CCNP

156

Q9H8S5
YREIMKLCENCPSCP

DICER1

186

Q9UPY3
QEICKATEVFMCPLC

ANO3

431

Q9BYT9
MKCIYCPIDTRLNFI

INTS9

441

Q9NV88
ETCIICCYEQRTMGK

VCPKMT

166

Q9H867
CRPKMIKSPYDVACC

IL18RAP

126

O95256
CQACRLRKCYEVGMV

ESR2

201

Q92731
PRTEKRTLCCDMVCF

MARCHF2

131

Q9P0N8
PTCCTRKMEERYQIA

GPC5

66

P78333
KSLPLYLQGMCIVCC

MMS22L

996

Q6ZRQ5
IMYPITLCLATLNCC

LPAR4

291

Q99677
EECKYAMLALNCICP

KCNT1

491

Q5JUK3
SCQACRLRKCYEVGM

ESR1

236

P03372
AVMAYDRCVAICKPL

OR2W3

116

Q7Z3T1
ISVPCKVSQCRCFMF

FAM221B

286

A6H8Z2
CMALVRDECLLPCKD

NPLOC4

391

Q8TAT6
CRDMYECSCPELDQL

GALK2

371

Q01415
LTTEKYECMVCCELV

NFX1

351

Q12986
YECMVCCELVRVTAP

NFX1

356

Q12986
RCCELCKYEFIMETK

MARCHF8

121

Q5T0T0
FKMCLNYEVRVLCCE

MUC5AC

2201

P98088
PFKMCLNYEVRVLCC

MUC5AC

3306

P98088
KMCLNYEVRVLCCET

MUC5AC

3606

P98088
PFKMCLNYEVRVLCC

MUC5AC

4711

P98088
PAMTKCCNQLDVCYD

PLA2G12B

106

Q9BX93
RCCELCKYDFIMETK

MARCHF1

121

Q8TCQ1
LTEKCNLRCQYCMPE

MOCS1

76

Q9NZB8
ECACMDLCKRHYKPV

FSTL5

86

Q8N475
RMIPCKHVFCYDCAI

CBLL1

121

Q75N03
CRVMCEQARLKCSPI

FZD10

106

Q9ULW2
EPMADSCIYECIRNK

WDPCP

311

O95876
PIYCICRKPDINCFM

CXXC1

26

Q9P0U4
VMELLYCSCCKQSSV

IL34

171

Q6ZMJ4
FITDNPCIMCVCLNK

BMPER

61

Q8N8U9
YRSCVTDMCECPVHK

BMPER

581

Q8N8U9
RKNMACYCRIPACIA

DEFA1

61

P59665
RADMCAALCYEILKC

DOCK9

1471

Q9BZ29
RKNMDCYCRIPACIA

DEFA3

61

P59666
YTTMCIKETCRLIPA

CYP4X1

366

Q8N118
RCSVCKMVIYCDQTC

ANKMY2

331

Q8IV38
CCVEVLPDRDGKRCM

DEF6

266

Q9H4E7
QCVICCPMELAKTRL

SLC25A29

106

Q8N8R3
CKYLCTGRACCQMLE

MARVELD3

191

Q96A59
ERKSPYVAVCCIVMA

TMEM167A

51

Q8TBQ9
DNVCLREPCENYMKC

CELSR3

1376

Q9NYQ7
REPCENYMKCVSVLR

CELSR3

1381

Q9NYQ7
PESCNHVFCMTCILK

SCAF11

56

Q99590
KDCVFCELTDSMQCP

SPACA4

21

Q8TDM5
IMKPIHECCYCDIKV

SACS

1391

Q9NZJ4
MGCRCCKIIQSYLFD

C4orf19

1

Q8IY42
QLCYSCRVNMKDLPS

CTU2

461

Q2VPK5
CMICLAAEYPAVKFC

PDCL

201

Q13371
MELKPNTCYCLSVRA

FNDC8

246

Q8TC99
YCEEDQMPICVVCDR

TRIM27

106

P14373
YMLTRCIQACKTNPE

NKRF

201

O15226
RLMKRLCPSSCDFCY

MMP23B

276

O75900
PVADCMKYRSCADCV

SEMA4C

496

Q9C0C4
MKYRSCADCVLARDP

SEMA4C

501

Q9C0C4
QHYMECCPDFKRVCT

PRG4

51

Q92954
SAACIQCLDCRLMYP

SKI

241

P12755
KDQEYCVCEMPCNLT

ASIC1

356

P78348
CVCEMPCNLTRYGKE

ASIC1

361

P78348
CLPCALCQMARELKI

CNFN

96

Q9BYD5
TMCIKECLRLYAPVV

CYP4Z1

366

Q86W10
KPKMYRSIEGCCICR

SINHCAF

6

Q9NP50
SSECFMDLVCPEKCR

SLIT3

496

O75094
CCPVCREISQQMYFK

TRIM77

51

I1YAP6
CVTKLCRADDCPFLM

ZPLD1

296

Q8TCW7
CEVYLCDTMNEKCKP

UMOD

566

P07911
CICEECSVPRCLMYE

RFX8

31

Q6ZV50
IERDMCTYCRKPLGV

SCEL

616

O95171
SKYECPICLMALREA

TRAF6

66

Q9Y4K3
VFCKEDLMVLCPLCT

TRIM75

106

A6NK02
HRYQMGCECKITRCP

TIMP2

146

P16035
ICFTMCCIYRPLKPR

TRPV6

381

Q9H1D0
DVFCYRMKDVNCTCK

STAB2

2286

Q8WWQ8
YQCIKCMVALFSSCP

USP9Y

2386

O00507
LCAVYMPKCENDRVE

SMO

126

Q99835
HPVCYRCSTKMRVLC

ZNF598

46

Q86UK7
RMCFVDPVRQCAECA

ZFYVE21

86

Q9BQ24
TMPAEAKTYRCRDCV

ZNF462

1361

Q96JM2
QPEKPCFRYRCMACL

TTC16

166

Q8NEE8
MADPEVCCFITKILC

ZC3HAV1

1

Q7Z2W4
MPKSCAARQCCNRYS

THAP3

1

Q8WTV1
SLMCEVCAFACKRKY

ZNF142

511

P52746
YRCHTIMNCTRTCPK

SDHB

241

P21912
EILNMEPYCCRETLK

USP44

596

Q9H0E7